Caenorhabditis elegans

38 known processes

che-12 (CELE_B0024.8)

Protein CHE-12

che-12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
locomotion GO:0040011 1634 0.172
cellular component movement GO:0006928 388 0.145
response to chemical GO:0042221 356 0.123
cell part morphogenesis GO:0032990 152 0.121
embryo development GO:0009790 3052 0.116
embryo development ending in birth or egg hatching GO:0009792 2992 0.111
establishment of localization GO:0051234 1171 0.100
multicellular organismal reproductive process GO:0048609 815 0.095
organelle organization GO:0006996 783 0.093
transport GO:0006810 1093 0.081
cell development GO:0048468 696 0.080
macromolecule localization GO:0033036 771 0.079
multi organism reproductive process GO:0044703 867 0.078
positive regulation of cellular process GO:0048522 332 0.077
single organism reproductive process GO:0044702 1196 0.076
head development GO:0060322 1 0.075
single organism localization GO:1902578 518 0.075
regulation of biological quality GO:0065008 741 0.072
regulation of multicellular organismal process GO:0051239 726 0.071
apoptotic process GO:0006915 478 0.065
lipid storage GO:0019915 565 0.064
behavior GO:0007610 527 0.062
hermaphrodite genitalia development GO:0040035 734 0.062
protein catabolic process GO:0030163 162 0.062
lipid localization GO:0010876 573 0.060
maintenance of location GO:0051235 580 0.060
single organism transport GO:0044765 447 0.059
growth GO:0040007 562 0.059
reproductive system development GO:0061458 850 0.059
development of primary sexual characteristics GO:0045137 840 0.058
signal transduction GO:0007165 317 0.058
developmental process involved in reproduction GO:0003006 1165 0.055
neuron development GO:0048666 199 0.055
cell projection organization GO:0030030 231 0.055
death GO:0016265 547 0.053
regulation of developmental process GO:0050793 684 0.052
regulation of growth GO:0040008 409 0.052
multicellular organismal aging GO:0010259 812 0.052
sexual reproduction GO:0019953 546 0.050
macromolecule catabolic process GO:0009057 202 0.050
sex differentiation GO:0007548 909 0.049
receptor mediated endocytosis GO:0006898 715 0.049
single organism organelle organization GO:1902589 501 0.048
reproductive structure development GO:0048608 850 0.047
nucleobase containing compound metabolic process GO:0006139 406 0.047
protein metabolic process GO:0019538 422 0.046
organic substance catabolic process GO:1901575 294 0.046
signaling GO:0023052 401 0.045
response to external stimulus GO:0009605 289 0.045
positive regulation of developmental process GO:0051094 408 0.045
axonogenesis GO:0007409 102 0.045
cell death GO:0008219 547 0.044
aging GO:0007568 812 0.043
localization of cell GO:0051674 313 0.043
regulation of localization GO:0032879 194 0.043
programmed cell death GO:0012501 500 0.043
positive regulation of multicellular organism growth GO:0040018 352 0.042
axon development GO:0061564 163 0.042
organ development GO:0048513 1102 0.040
protein localization GO:0008104 205 0.040
negative regulation of biological process GO:0048519 567 0.040
gonad development GO:0008406 840 0.040
cell migration GO:0016477 306 0.039
regulation of metabolic process GO:0019222 478 0.038
regulation of response to stimulus GO:0048583 243 0.038
catabolic process GO:0009056 318 0.038
cellular component morphogenesis GO:0032989 318 0.038
determination of adult lifespan GO:0008340 812 0.038
guanosine containing compound catabolic process GO:1901069 48 0.037
multicellular organism growth GO:0035264 385 0.037
multicellular organism reproduction GO:0032504 819 0.037
organelle assembly GO:0070925 214 0.037
genitalia development GO:0048806 741 0.036
multi organism behavior GO:0051705 389 0.036
post embryonic development GO:0009791 2152 0.036
cell motility GO:0048870 313 0.036
regulation of signaling GO:0023051 172 0.036
cytoskeleton organization GO:0007010 339 0.035
immune response GO:0006955 192 0.035
regulation of multicellular organismal development GO:2000026 317 0.035
single organism signaling GO:0044700 401 0.035
developmental growth GO:0048589 412 0.035
positive regulation of multicellular organismal process GO:0051240 417 0.035
regulation of cell communication GO:0010646 176 0.034
phosphorus metabolic process GO:0006793 232 0.033
positive regulation of developmental growth GO:0048639 354 0.033
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.033
regulation of multicellular organism growth GO:0040014 373 0.033
phosphate containing compound metabolic process GO:0006796 232 0.033
nervous system development GO:0007399 253 0.032
neuron differentiation GO:0030182 217 0.032
macromolecular complex subunit organization GO:0043933 320 0.032
cell cycle process GO:0022402 482 0.032
regulation of developmental growth GO:0048638 389 0.032
cellular component assembly GO:0022607 293 0.031
multi organism reproductive behavior GO:0044705 387 0.031
generation of neurons GO:0048699 235 0.031
cellular protein metabolic process GO:0044267 279 0.031
transcription from rna polymerase ii promoter GO:0006366 149 0.031
reproductive behavior GO:0019098 387 0.031
rna biosynthetic process GO:0032774 169 0.031
multi multicellular organism process GO:0044706 390 0.030
regulation of primary metabolic process GO:0080090 292 0.030
sensory organ morphogenesis GO:0090596 2 0.030
defense response GO:0006952 296 0.029
organic cyclic compound catabolic process GO:1901361 119 0.029
cellular component biogenesis GO:0044085 297 0.029
establishment of localization in cell GO:0051649 318 0.029
secretion GO:0046903 147 0.029
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.028
negative regulation of metabolic process GO:0009892 240 0.028
regulation of cellular metabolic process GO:0031323 305 0.028
cellular localization GO:0051641 360 0.028
cell cell signaling GO:0007267 118 0.028
body morphogenesis GO:0010171 620 0.027
negative regulation of cellular process GO:0048523 239 0.027
neuron projection development GO:0031175 187 0.027
macromolecular complex assembly GO:0065003 193 0.027
vesicle mediated transport GO:0016192 852 0.027
cellular component assembly involved in morphogenesis GO:0010927 183 0.027
neurogenesis GO:0022008 236 0.027
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.027
gamete generation GO:0007276 461 0.026
cell projection morphogenesis GO:0048858 148 0.026
gene expression GO:0010467 412 0.026
positive regulation of post embryonic development GO:0048582 54 0.026
regulation of gene expression GO:0010468 366 0.026
multicellular organismal reproductive behavior GO:0033057 384 0.026
glycosyl compound metabolic process GO:1901657 100 0.025
cilium morphogenesis GO:0060271 33 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.025
macromolecule biosynthetic process GO:0009059 250 0.025
macromolecule modification GO:0043412 218 0.024
cellular biosynthetic process GO:0044249 315 0.024
negative regulation of macromolecule metabolic process GO:0010605 229 0.024
organonitrogen compound metabolic process GO:1901564 151 0.024
oviposition GO:0018991 364 0.024
cellular protein modification process GO:0006464 207 0.024
small molecule metabolic process GO:0044281 186 0.024
nucleic acid metabolic process GO:0090304 299 0.024
positive regulation of neuron differentiation GO:0045666 4 0.023
negative regulation of gene expression GO:0010629 217 0.023
carbohydrate derivative metabolic process GO:1901135 141 0.023
protein modification process GO:0036211 207 0.023
epithelial cell proliferation GO:0050673 1 0.023
regulation of macromolecule metabolic process GO:0060255 421 0.023
cellular catabolic process GO:0044248 199 0.023
regulation of nitrogen compound metabolic process GO:0051171 222 0.023
cellular nitrogen compound biosynthetic process GO:0044271 192 0.022
purine nucleoside metabolic process GO:0042278 92 0.022
positive regulation of metabolic process GO:0009893 187 0.022
negative regulation of developmental process GO:0051093 227 0.022
oogenesis GO:0048477 229 0.021
protein complex subunit organization GO:0071822 280 0.021
positive regulation of gtpase activity GO:0043547 28 0.021
positive regulation of cellular metabolic process GO:0031325 178 0.021
response to wounding GO:0009611 4 0.021
negative regulation of multicellular organismal process GO:0051241 236 0.021
regulation of signal transduction GO:0009966 135 0.021
regulation of biosynthetic process GO:0009889 189 0.021
regulation of organelle organization GO:0033043 164 0.021
actin cytoskeleton organization GO:0030036 184 0.021
microtubule based process GO:0007017 182 0.021
molting cycle GO:0042303 281 0.020
organic acid metabolic process GO:0006082 47 0.020
rna metabolic process GO:0016070 228 0.020
ribonucleoside triphosphate metabolic process GO:0009199 87 0.020
nucleoside triphosphate metabolic process GO:0009141 87 0.020
cell division GO:0051301 262 0.020
anatomical structure formation involved in morphogenesis GO:0048646 250 0.020
cell cycle GO:0007049 526 0.020
nucleotide metabolic process GO:0009117 108 0.020
epithelial tube morphogenesis GO:0060562 1 0.020
secretion by cell GO:0032940 138 0.019
response to organic substance GO:0010033 131 0.019
carboxylic acid metabolic process GO:0019752 34 0.019
regulation of nematode larval development GO:0061062 260 0.019
regulation of post embryonic development GO:0048580 260 0.019
ribonucleotide metabolic process GO:0009259 99 0.019
muscle organ morphogenesis GO:0048644 4 0.019
regulation of nucleic acid templated transcription GO:1903506 165 0.019
endocytosis GO:0006897 819 0.019
regulation of transcription dna templated GO:0006355 164 0.019
purine nucleoside triphosphate catabolic process GO:0009146 72 0.019
protein complex biogenesis GO:0070271 186 0.019
ribose phosphate metabolic process GO:0019693 99 0.019
vulval development GO:0040025 333 0.019
organelle fission GO:0048285 363 0.019
response to abiotic stimulus GO:0009628 152 0.019
regulation of cytoplasmic transport GO:1903649 3 0.019
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.019
regulation of cellular component organization GO:0051128 248 0.019
positive regulation of growth GO:0045927 369 0.019
regulation of cell cycle GO:0051726 194 0.018
regulation of cytoskeleton organization GO:0051493 41 0.018
nucleobase containing compound catabolic process GO:0034655 114 0.018
regulation of macromolecule biosynthetic process GO:0010556 189 0.018
neuron projection morphogenesis GO:0048812 114 0.018
striated muscle myosin thick filament assembly GO:0071688 138 0.018
response to biotic stimulus GO:0009607 101 0.018
regulation of transport GO:0051049 91 0.018
transmembrane transport GO:0055085 110 0.018
purine ribonucleoside metabolic process GO:0046128 92 0.018
regulation of organ morphogenesis GO:2000027 4 0.018
nucleoside metabolic process GO:0009116 99 0.018
organic substance biosynthetic process GO:1901576 323 0.018
organophosphate catabolic process GO:0046434 81 0.018
cation transport GO:0006812 78 0.017
purine nucleoside triphosphate metabolic process GO:0009144 87 0.017
oxoacid metabolic process GO:0043436 47 0.017
single organism behavior GO:0044708 83 0.017
nucleoside triphosphate catabolic process GO:0009143 72 0.017
positive regulation of gene expression GO:0010628 112 0.017
single organism catabolic process GO:0044712 129 0.017
nucleoside phosphate metabolic process GO:0006753 108 0.017
neuromuscular junction development GO:0007528 2 0.017
response to temperature stimulus GO:0009266 66 0.017
cell morphogenesis GO:0000902 163 0.017
cellular response to chemical stimulus GO:0070887 129 0.017
protein complex assembly GO:0006461 186 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.017
intracellular signal transduction GO:0035556 96 0.017
lipid metabolic process GO:0006629 77 0.016
defense response to bacterium GO:0042742 86 0.016
olfactory behavior GO:0042048 27 0.016
myosin filament organization GO:0031033 138 0.016
heterocycle catabolic process GO:0046700 119 0.016
regulation of intracellular signal transduction GO:1902531 77 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.016
regulation of rna metabolic process GO:0051252 173 0.016
cellular macromolecule biosynthetic process GO:0034645 247 0.016
regulation of cell cycle process GO:0010564 145 0.016
actin filament based process GO:0030029 191 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.015
response to external biotic stimulus GO:0043207 101 0.015
regulation of cellular biosynthetic process GO:0031326 189 0.015
cellular nitrogen compound catabolic process GO:0044270 119 0.015
heterocycle biosynthetic process GO:0018130 187 0.015
regulation of nucleoside metabolic process GO:0009118 37 0.015
striated muscle cell development GO:0055002 157 0.015
muscle structure development GO:0061061 191 0.015
taxis GO:0042330 128 0.015
purine containing compound catabolic process GO:0072523 75 0.015
regulation of epithelial cell proliferation GO:0050678 1 0.015
regulation of cell proliferation GO:0042127 105 0.015
regulation of lipid metabolic process GO:0019216 4 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.015
meiotic cell cycle GO:0051321 335 0.015
biosynthetic process GO:0009058 323 0.015
ion transport GO:0006811 113 0.015
nucleoside catabolic process GO:0009164 78 0.015
regulation of cation channel activity GO:2001257 3 0.015
negative regulation of neurogenesis GO:0050768 4 0.015
organic cyclic compound biosynthetic process GO:1901362 195 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.015
regulation of apoptotic signaling pathway GO:2001233 1 0.015
system process GO:0003008 136 0.015
regulation of locomotion GO:0040012 161 0.014
aromatic compound catabolic process GO:0019439 116 0.014
cellular amino acid metabolic process GO:0006520 15 0.014
ras protein signal transduction GO:0007265 31 0.014
microtubule based movement GO:0007018 33 0.014
nucleic acid templated transcription GO:0097659 169 0.014
aromatic compound biosynthetic process GO:0019438 192 0.014
carbohydrate derivative catabolic process GO:1901136 82 0.014
response to other organism GO:0051707 101 0.014
purine nucleotide catabolic process GO:0006195 75 0.014
rna interference GO:0016246 137 0.014
germ cell development GO:0007281 351 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.014
purine ribonucleotide metabolic process GO:0009150 95 0.014
regeneration GO:0031099 4 0.014
organophosphate metabolic process GO:0019637 125 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.014
cell proliferation GO:0008283 116 0.014
cellular macromolecular complex assembly GO:0034622 184 0.014
organonitrogen compound catabolic process GO:1901565 90 0.014
cell type specific apoptotic process GO:0097285 4 0.014
purine containing compound metabolic process GO:0072521 95 0.014
response to acid chemical GO:0001101 4 0.014
protein oligomerization GO:0051259 4 0.014
nucleoside phosphate catabolic process GO:1901292 77 0.014
post embryonic organ development GO:0048569 336 0.014
response to bacterium GO:0009617 86 0.014
positive regulation of phosphate metabolic process GO:0045937 56 0.013
canonical wnt signaling pathway GO:0060070 3 0.013
myosin filament assembly GO:0031034 138 0.013
axon guidance GO:0007411 82 0.013
myofibril assembly GO:0030239 154 0.013
protein phosphorylation GO:0006468 85 0.013
posttranscriptional gene silencing by rna GO:0035194 143 0.013
posttranscriptional regulation of gene expression GO:0010608 166 0.013
glycosyl compound catabolic process GO:1901658 79 0.013
regulation of molecular function GO:0065009 89 0.013
nucleotide catabolic process GO:0009166 77 0.013
regulation of phosphorus metabolic process GO:0051174 81 0.013
nucleobase containing compound biosynthetic process GO:0034654 184 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
positive regulation of epithelial cell proliferation GO:0050679 1 0.013
posttranscriptional gene silencing GO:0016441 143 0.013
positive regulation of rna biosynthetic process GO:1902680 102 0.013
female gamete generation GO:0007292 254 0.013
cellular amine metabolic process GO:0044106 15 0.013
purine ribonucleoside catabolic process GO:0046130 75 0.013
neurotransmitter transport GO:0006836 32 0.012
purine nucleotide metabolic process GO:0006163 95 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
small gtpase mediated signal transduction GO:0007264 32 0.012
positive regulation of molecular function GO:0044093 61 0.012
regulation of purine nucleotide catabolic process GO:0033121 35 0.012
cell recognition GO:0008037 85 0.012
ribonucleoside metabolic process GO:0009119 98 0.012
regulation of nucleocytoplasmic transport GO:0046822 3 0.012
regulation of behavior GO:0050795 97 0.012
regulation of phosphate metabolic process GO:0019220 81 0.012
positive regulation of catabolic process GO:0009896 38 0.012
innate immune response GO:0045087 190 0.012
regulation of gene expression epigenetic GO:0040029 163 0.012
adult behavior GO:0030534 3 0.012
bmp signaling pathway GO:0030509 3 0.012
amine metabolic process GO:0009308 15 0.012
regulation of response to wounding GO:1903034 1 0.012
ribonucleoside catabolic process GO:0042454 77 0.012
nucleobase containing small molecule metabolic process GO:0055086 115 0.012
inorganic ion transmembrane transport GO:0098660 54 0.012
actomyosin structure organization GO:0031032 154 0.012
mating GO:0007618 34 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.012
neuron recognition GO:0008038 83 0.012
regulation of vulval development GO:0040028 248 0.012
cellular protein complex assembly GO:0043623 178 0.012
gtp metabolic process GO:0046039 46 0.012
cell morphogenesis involved in differentiation GO:0000904 112 0.012
ribonucleotide catabolic process GO:0009261 75 0.012
transcription dna templated GO:0006351 168 0.012
positive regulation of protein transport GO:0051222 4 0.011
phosphorylation GO:0016310 116 0.011
regulation of cell differentiation GO:0045595 81 0.011
cellular response to stress GO:0033554 162 0.011
gene silencing by rna GO:0031047 143 0.011
male mating behavior GO:0060179 26 0.011
regulation of protein targeting GO:1903533 3 0.011
neuron projection guidance GO:0097485 82 0.011
ribonucleoside triphosphate catabolic process GO:0009203 72 0.011
regulation of small gtpase mediated signal transduction GO:0051056 41 0.011
cellular response to inorganic substance GO:0071241 3 0.011
chromosome organization GO:0051276 104 0.011
regulation of catabolic process GO:0009894 57 0.011
striated muscle cell differentiation GO:0051146 158 0.011
response to osmotic stress GO:0006970 29 0.011
collagen and cuticulin based cuticle development GO:0040002 99 0.011
regulation of cellular component movement GO:0051270 62 0.011
axonal fasciculation GO:0007413 79 0.011
regulation of protein localization GO:0032880 50 0.011
purine nucleoside catabolic process GO:0006152 75 0.011
single organism biosynthetic process GO:0044711 91 0.011
positive regulation of cellular catabolic process GO:0031331 35 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
positive regulation of catalytic activity GO:0043085 59 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
intracellular transport GO:0046907 77 0.011
negative regulation of cell communication GO:0010648 61 0.010
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.010
cuticle development GO:0042335 100 0.010
muscle cell development GO:0055001 158 0.010
defense response to other organism GO:0098542 100 0.010
cellular response to abiotic stimulus GO:0071214 4 0.010
positive regulation of nematode larval development GO:0061063 54 0.010
positive regulation of intracellular transport GO:0032388 2 0.010
regulation of protein import into nucleus GO:0042306 3 0.010
negative regulation of signal transduction GO:0009968 60 0.010
gtp catabolic process GO:0006184 46 0.010
cellular lipid metabolic process GO:0044255 40 0.010
positive regulation of macromolecule metabolic process GO:0010604 149 0.010
gene silencing GO:0016458 143 0.010
phagocytosis GO:0006909 115 0.010
positive regulation of gtp catabolic process GO:0033126 28 0.010
positive regulation of signaling GO:0023056 66 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.010
response to inorganic substance GO:0010035 50 0.010
mating behavior GO:0007617 32 0.010
negative regulation of post embryonic development GO:0048581 208 0.010
positive regulation of phosphorus metabolic process GO:0010562 56 0.010

che-12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.011
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010