Caenorhabditis elegans

41 known processes

pkd-2 (CELE_Y73F8A.1)

Protein PKD-2

pkd-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism reproductive process GO:0044702 1196 0.320
Mouse
locomotion GO:0040011 1634 0.285
sexual reproduction GO:0019953 546 0.277
establishment of localization GO:0051234 1171 0.277
transport GO:0006810 1093 0.267
post embryonic development GO:0009791 2152 0.263
embryo development GO:0009790 3052 0.217
Human Zebrafish Mouse
multi organism reproductive process GO:0044703 867 0.208
mating behavior GO:0007617 32 0.206
multicellular organism reproduction GO:0032504 819 0.192
organ development GO:0048513 1102 0.163
Human Zebrafish Mouse
single organism transport GO:0044765 447 0.157
determination of adult lifespan GO:0008340 812 0.151
establishment of localization in cell GO:0051649 318 0.145
Human Mouse
multi organism reproductive behavior GO:0044705 387 0.140
multicellular organismal reproductive process GO:0048609 815 0.132
negative regulation of biological process GO:0048519 567 0.130
Human Mouse
developmental process involved in reproduction GO:0003006 1165 0.127
Mouse
single organism localization GO:1902578 518 0.125
vesicle mediated transport GO:0016192 852 0.121
organelle organization GO:0006996 783 0.113
multi multicellular organism process GO:0044706 390 0.111
cell cycle GO:0007049 526 0.111
Human Mouse
embryo development ending in birth or egg hatching GO:0009792 2992 0.110
Human Mouse
macromolecule localization GO:0033036 771 0.107
Human
hermaphrodite genitalia development GO:0040035 734 0.106
aging GO:0007568 812 0.105
multicellular organismal aging GO:0010259 812 0.102
cell development GO:0048468 696 0.100
single organism organelle organization GO:1902589 501 0.099
development of primary sexual characteristics GO:0045137 840 0.098
multicellular organismal reproductive behavior GO:0033057 384 0.092
regulation of growth GO:0040008 409 0.090
reproductive behavior GO:0019098 387 0.088
regulation of biological quality GO:0065008 741 0.087
Human Mouse
behavior GO:0007610 527 0.086
cellular localization GO:0051641 360 0.084
Human Mouse
receptor mediated endocytosis GO:0006898 715 0.081
multi organism behavior GO:0051705 389 0.080
gonad development GO:0008406 840 0.077
signal transduction GO:0007165 317 0.076
Human Zebrafish Mouse
endocytosis GO:0006897 819 0.075
reproductive structure development GO:0048608 850 0.072
Mouse
reproductive system development GO:0061458 850 0.072
Mouse
cytoskeleton organization GO:0007010 339 0.067
cellular component movement GO:0006928 388 0.066
microtubule based process GO:0007017 182 0.066
regulation of macromolecule metabolic process GO:0060255 421 0.065
Human Zebrafish Mouse
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.064
maintenance of location GO:0051235 580 0.062
Human Mouse
oviposition GO:0018991 364 0.062
regulation of developmental process GO:0050793 684 0.062
genitalia development GO:0048806 741 0.062
lipid localization GO:0010876 573 0.061
regulation of cytoplasmic transport GO:1903649 3 0.059
Human
single organism signaling GO:0044700 401 0.059
Human Zebrafish Mouse
lipid storage GO:0019915 565 0.059
regulation of metabolic process GO:0019222 478 0.058
Human Zebrafish Mouse
growth GO:0040007 562 0.057
sex differentiation GO:0007548 909 0.057
cell cycle process GO:0022402 482 0.054
Human Mouse
positive regulation of developmental process GO:0051094 408 0.053
protein localization GO:0008104 205 0.053
Human
regulation of multicellular organismal process GO:0051239 726 0.053
Zebrafish
cellular component biogenesis GO:0044085 297 0.052
body morphogenesis GO:0010171 620 0.052
protein complex subunit organization GO:0071822 280 0.051
regulation of developmental growth GO:0048638 389 0.050
organelle assembly GO:0070925 214 0.050
signaling GO:0023052 401 0.050
Human Zebrafish Mouse
gamete generation GO:0007276 461 0.050
protein metabolic process GO:0019538 422 0.049
Human
multicellular organism growth GO:0035264 385 0.049
response to chemical GO:0042221 356 0.048
Human Mouse
positive regulation of developmental growth GO:0048639 354 0.048
cellular protein localization GO:0034613 75 0.048
Human
cilium assembly GO:0042384 28 0.048
nucleic acid metabolic process GO:0090304 299 0.048
Human
single organism cellular localization GO:1902580 72 0.047
Human
gene expression GO:0010467 412 0.046
Human Mouse
positive regulation of multicellular organism growth GO:0040018 352 0.045
positive regulation of growth GO:0045927 369 0.044
head development GO:0060322 1 0.044
regulation of multicellular organism growth GO:0040014 373 0.044
developmental growth GO:0048589 412 0.044
regulation of cellular component organization GO:0051128 248 0.043
system process GO:0003008 136 0.042
Zebrafish Mouse
cellular component assembly GO:0022607 293 0.042
mating GO:0007618 34 0.041
regulation of primary metabolic process GO:0080090 292 0.041
Human Mouse
intraciliary transport GO:0042073 12 0.040
molting cycle GO:0042303 281 0.040
regulation of transcription dna templated GO:0006355 164 0.040
Human
macromolecule catabolic process GO:0009057 202 0.040
fertilization GO:0009566 63 0.040
cellular component assembly involved in morphogenesis GO:0010927 183 0.038
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.038
regulation of nucleocytoplasmic transport GO:0046822 3 0.036
Human
cell motility GO:0048870 313 0.035
negative regulation of macromolecule metabolic process GO:0010605 229 0.034
cell part morphogenesis GO:0032990 152 0.034
secretion by cell GO:0032940 138 0.034
organelle fission GO:0048285 363 0.034
mitotic cell cycle process GO:1903047 194 0.034
Human
regulation of gene expression GO:0010468 366 0.034
Human Mouse
regulation of cell cycle GO:0051726 194 0.033
Human Mouse
single fertilization GO:0007338 61 0.033
regulation of locomotion GO:0040012 161 0.033
negative regulation of cellular process GO:0048523 239 0.033
Human Mouse
cellular protein metabolic process GO:0044267 279 0.033
Human
localization of cell GO:0051674 313 0.033
sensory perception of chemical stimulus GO:0007606 15 0.032
Mouse
organic substance biosynthetic process GO:1901576 323 0.031
Human Zebrafish
generation of neurons GO:0048699 235 0.031
positive regulation of multicellular organismal process GO:0051240 417 0.031
cell death GO:0008219 547 0.030
intracellular transport GO:0046907 77 0.029
Human Mouse
rna metabolic process GO:0016070 228 0.028
Human
membrane organization GO:0061024 135 0.028
regulation of nucleic acid templated transcription GO:1903506 165 0.027
Human
negative regulation of metabolic process GO:0009892 240 0.027
cilium morphogenesis GO:0060271 33 0.027
regulation of rna metabolic process GO:0051252 173 0.026
Human
cellular response to abiotic stimulus GO:0071214 4 0.026
Human Mouse
adult behavior GO:0030534 3 0.026
macromolecular complex subunit organization GO:0043933 320 0.026
regulation of nitrogen compound metabolic process GO:0051171 222 0.026
Human Mouse
death GO:0016265 547 0.026
macromolecule modification GO:0043412 218 0.026
Human
cellular component morphogenesis GO:0032989 318 0.026
secretion GO:0046903 147 0.025
protein modification process GO:0036211 207 0.025
Human
regulation of organelle organization GO:0033043 164 0.025
negative regulation of gene expression GO:0010629 217 0.025
programmed cell death GO:0012501 500 0.025
catabolic process GO:0009056 318 0.024
germ cell development GO:0007281 351 0.024
microtubule based movement GO:0007018 33 0.024
biosynthetic process GO:0009058 323 0.024
Human Zebrafish Mouse
apoptotic process GO:0006915 478 0.024
protein localization to organelle GO:0033365 37 0.024
Human
neuron projection development GO:0031175 187 0.024
macromolecule biosynthetic process GO:0009059 250 0.024
Human Zebrafish
regulation of nematode larval development GO:0061062 260 0.024
epithelial tube morphogenesis GO:0060562 1 0.023
Human Zebrafish Mouse
cellular nitrogen compound biosynthetic process GO:0044271 192 0.023
Human Mouse
neuron development GO:0048666 199 0.023
cellular catabolic process GO:0044248 199 0.023
vulval development GO:0040025 333 0.023
establishment or maintenance of cell polarity GO:0007163 63 0.023
regulation of localization GO:0032879 194 0.023
Human Mouse
nervous system development GO:0007399 253 0.023
Human
regulation of cell cycle process GO:0010564 145 0.023
Human
nucleobase containing compound biosynthetic process GO:0034654 184 0.022
Human
regulation of post embryonic development GO:0048580 260 0.022
cellular biosynthetic process GO:0044249 315 0.022
Human Mouse
phosphate containing compound metabolic process GO:0006796 232 0.022
Human Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.021
Human
regulation of macromolecule biosynthetic process GO:0010556 189 0.021
Human Zebrafish
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.021
Human
negative regulation of nematode larval development GO:0061064 208 0.021
negative regulation of post embryonic development GO:0048581 208 0.021
oogenesis GO:0048477 229 0.021
single organism intracellular transport GO:1902582 70 0.021
Human Mouse
single organism behavior GO:0044708 83 0.021
cell migration GO:0016477 306 0.020
regulation of protein import into nucleus GO:0042306 3 0.020
Human
heterocycle biosynthetic process GO:0018130 187 0.020
Human
neuron differentiation GO:0030182 217 0.020
cellular macromolecule biosynthetic process GO:0034645 247 0.020
Human
establishment of cell polarity GO:0030010 46 0.020
ion transport GO:0006811 113 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.020
Human Mouse
meiotic cell cycle GO:0051321 335 0.019
response to abiotic stimulus GO:0009628 152 0.019
Human Mouse
cilium organization GO:0044782 32 0.019
regulation of cell motility GO:2000145 57 0.019
taxis GO:0042330 128 0.019
organelle localization GO:0051640 127 0.019
small molecule metabolic process GO:0044281 186 0.019
Mouse
cellular macromolecule localization GO:0070727 75 0.019
Human
protein complex assembly GO:0006461 186 0.019
cell projection morphogenesis GO:0048858 148 0.019
nucleobase containing compound metabolic process GO:0006139 406 0.019
Human Mouse
cell division GO:0051301 262 0.018
cell projection organization GO:0030030 231 0.018
aromatic compound biosynthetic process GO:0019438 192 0.018
Human
cellular protein modification process GO:0006464 207 0.018
Human
organic substance catabolic process GO:1901575 294 0.018
regulation of biosynthetic process GO:0009889 189 0.018
Human Zebrafish Mouse
protein catabolic process GO:0030163 162 0.018
protein complex biogenesis GO:0070271 186 0.018
organophosphate metabolic process GO:0019637 125 0.018
Mouse
regulation of protein targeting GO:1903533 3 0.017
Human
regulation of protein localization GO:0032880 50 0.017
Human
intracellular signal transduction GO:0035556 96 0.017
Human Zebrafish Mouse
male mating behavior GO:0060179 26 0.017
regulation of multicellular organismal development GO:2000026 317 0.017
anatomical structure formation involved in morphogenesis GO:0048646 250 0.017
establishment of organelle localization GO:0051656 123 0.017
negative regulation of developmental process GO:0051093 227 0.016
positive regulation of cellular process GO:0048522 332 0.016
Human Mouse
nucleic acid templated transcription GO:0097659 169 0.016
Human
regulation of gene expression epigenetic GO:0040029 163 0.016
phosphorus metabolic process GO:0006793 232 0.016
Human Mouse
axonogenesis GO:0007409 102 0.016
organic cyclic compound catabolic process GO:1901361 119 0.016
meiotic nuclear division GO:0007126 300 0.016
muscle contraction GO:0006936 43 0.016
Zebrafish
cellular macromolecular complex assembly GO:0034622 184 0.016
macromolecular complex assembly GO:0065003 193 0.016
regulation of cellular metabolic process GO:0031323 305 0.015
Human Mouse
mitotic spindle organization GO:0007052 81 0.015
spindle organization GO:0007051 92 0.015
regulation of response to stimulus GO:0048583 243 0.015
Human
gene silencing GO:0016458 143 0.015
regulation of mitotic cell cycle GO:0007346 76 0.015
Human
negative regulation of response to stimulus GO:0048585 73 0.015
gene silencing by rna GO:0031047 143 0.015
pattern specification process GO:0007389 59 0.015
Human Zebrafish Mouse
posttranscriptional gene silencing by rna GO:0035194 143 0.015
heterocycle catabolic process GO:0046700 119 0.015
lipid metabolic process GO:0006629 77 0.015
posttranscriptional regulation of gene expression GO:0010608 166 0.015
response to external stimulus GO:0009605 289 0.015
Mouse
axon development GO:0061564 163 0.015
cellular nitrogen compound catabolic process GO:0044270 119 0.014
dauer larval development GO:0040024 92 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.014
ribonucleoside triphosphate metabolic process GO:0009199 87 0.014
regulation of signal transduction GO:0009966 135 0.014
Human
rna interference GO:0016246 137 0.014
post embryonic organ development GO:0048569 336 0.014
organic substance transport GO:0071702 113 0.014
Human
response to wounding GO:0009611 4 0.014
male sex differentiation GO:0046661 86 0.014
regulation of striated muscle contraction GO:0006942 4 0.014
Zebrafish
posttranscriptional gene silencing GO:0016441 143 0.014
rna localization GO:0006403 3 0.014
turning behavior involved in mating GO:0034607 12 0.014
male anatomical structure morphogenesis GO:0090598 78 0.014
cell morphogenesis GO:0000902 163 0.013
regulation of vulval development GO:0040028 248 0.013
ribose phosphate metabolic process GO:0019693 99 0.013
Mouse
myosin filament assembly GO:0031034 138 0.013
oxoacid metabolic process GO:0043436 47 0.013
negative regulation of multicellular organismal process GO:0051241 236 0.013
chemosensory behavior GO:0007635 33 0.013
establishment of spindle localization GO:0051293 51 0.013
neurogenesis GO:0022008 236 0.013
striated muscle cell differentiation GO:0051146 158 0.013
cellular response to stress GO:0033554 162 0.013
Human Mouse
female gamete generation GO:0007292 254 0.013
protein phosphorylation GO:0006468 85 0.013
Human
negative regulation of rna metabolic process GO:0051253 53 0.013
actin cytoskeleton organization GO:0030036 184 0.013
cation transport GO:0006812 78 0.013
regulation of protein metabolic process GO:0051246 81 0.013
Human
regulation of axon extension GO:0030516 20 0.013
tube development GO:0035295 126 0.013
Human Zebrafish Mouse
negative regulation of gene expression epigenetic GO:0045814 2 0.013
organonitrogen compound metabolic process GO:1901564 151 0.013
Mouse
cytoskeleton dependent intracellular transport GO:0030705 19 0.012
microtubule based transport GO:0010970 19 0.012
nonmotile primary cilium assembly GO:0035058 18 0.012
oocyte axis specification GO:0007309 2 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.012
myosin filament organization GO:0031033 138 0.012
regulation of rna biosynthetic process GO:2001141 165 0.012
Human
regulation of lipid metabolic process GO:0019216 4 0.012
nucleobase containing compound catabolic process GO:0034655 114 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
regulation of cell proliferation GO:0042127 105 0.012
Human
single organism catabolic process GO:0044712 129 0.012
digestive system development GO:0055123 122 0.012
single organism membrane organization GO:0044802 35 0.012
cellular macromolecule catabolic process GO:0044265 73 0.012
ribonucleoprotein complex assembly GO:0022618 4 0.012
striated muscle myosin thick filament assembly GO:0071688 138 0.012
muscle tissue development GO:0060537 1 0.012
Human
negative regulation of vulval development GO:0040027 206 0.012
olfactory behavior GO:0042048 27 0.012
regulation of cell communication GO:0010646 176 0.012
Human
oocyte construction GO:0007308 2 0.012
organic cyclic compound biosynthetic process GO:1901362 195 0.011
Human
regulation of exocytosis GO:0017157 1 0.011
pigmentation GO:0043473 2 0.011
cell morphogenesis involved in differentiation GO:0000904 112 0.011
nucleotide metabolic process GO:0009117 108 0.011
Mouse
cellular lipid metabolic process GO:0044255 40 0.011
cellular protein complex assembly GO:0043623 178 0.011
muscle cell development GO:0055001 158 0.011
aromatic compound catabolic process GO:0019439 116 0.011
mitotic nuclear division GO:0007067 89 0.011
axonal fasciculation GO:0007413 79 0.011
purine nucleoside triphosphate metabolic process GO:0009144 87 0.011
organic acid metabolic process GO:0006082 47 0.011
regulation of reproductive process GO:2000241 66 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.011
epithelial cell proliferation GO:0050673 1 0.011
negative regulation of response to external stimulus GO:0032102 3 0.011
regulation of meiosis GO:0040020 94 0.011
regulation of signaling GO:0023051 172 0.010
Human
adult locomotory behavior GO:0008344 1 0.010
regulation of synapse assembly GO:0051963 2 0.010
cell proliferation GO:0008283 116 0.010
Human
purine ribonucleotide metabolic process GO:0009150 95 0.010
Mouse
nucleoside metabolic process GO:0009116 99 0.010
tissue development GO:0009888 112 0.010
Human Zebrafish Mouse
single organism membrane fusion GO:0044801 13 0.010
regeneration GO:0031099 4 0.010
regulation of cellular localization GO:0060341 42 0.010
Human
purine ribonucleoside metabolic process GO:0046128 92 0.010
exocytosis GO:0006887 15 0.010
developmental cell growth GO:0048588 39 0.010
carboxylic acid metabolic process GO:0019752 34 0.010
cellular protein catabolic process GO:0044257 37 0.010
protein oligomerization GO:0051259 4 0.010

pkd-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013