Caenorhabditis elegans

102 known processes

gen-1 (CELE_T12A2.8)

Protein GEN-1

gen-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organ development GO:0048513 1102 0.316
negative regulation of post embryonic development GO:0048581 208 0.306
sex differentiation GO:0007548 909 0.296
rna metabolic process GO:0016070 228 0.287
gonad development GO:0008406 840 0.265
negative regulation of vulval development GO:0040027 206 0.262
establishment of localization GO:0051234 1171 0.259
nucleic acid templated transcription GO:0097659 169 0.251
vesicle mediated transport GO:0016192 852 0.239
multicellular organismal reproductive process GO:0048609 815 0.194
cell death GO:0008219 547 0.192
post embryonic organ development GO:0048569 336 0.192
negative regulation of nematode larval development GO:0061064 208 0.182
embryo development GO:0009790 3052 0.180
locomotion GO:0040011 1634 0.172
embryo development ending in birth or egg hatching GO:0009792 2992 0.166
genitalia development GO:0048806 741 0.162
multicellular organism reproduction GO:0032504 819 0.158
endocytosis GO:0006897 819 0.151
reproductive structure development GO:0048608 850 0.151
transport GO:0006810 1093 0.148
negative regulation of biological process GO:0048519 567 0.143
regulation of vulval development GO:0040028 248 0.135
negative regulation of multicellular organismal process GO:0051241 236 0.126
reproductive system development GO:0061458 850 0.122
development of primary sexual characteristics GO:0045137 840 0.121
cell development GO:0048468 696 0.119
negative regulation of developmental process GO:0051093 227 0.119
regulation of nematode larval development GO:0061062 260 0.115
vulval development GO:0040025 333 0.115
phosphorus metabolic process GO:0006793 232 0.113
nucleobase containing compound metabolic process GO:0006139 406 0.111
regulation of nitrogen compound metabolic process GO:0051171 222 0.110
regulation of macromolecule metabolic process GO:0060255 421 0.105
phosphate containing compound metabolic process GO:0006796 232 0.105
dna metabolic process GO:0006259 74 0.102
regulation of post embryonic development GO:0048580 260 0.101
germ cell development GO:0007281 351 0.100
organic substance biosynthetic process GO:1901576 323 0.100
cellular response to stress GO:0033554 162 0.099
multicellular organismal aging GO:0010259 812 0.094
macromolecular complex assembly GO:0065003 193 0.091
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.090
regulation of rna metabolic process GO:0051252 173 0.089
regulation of multicellular organismal process GO:0051239 726 0.087
purine ribonucleoside catabolic process GO:0046130 75 0.083
negative regulation of gene expression GO:0010629 217 0.082
behavior GO:0007610 527 0.079
gene expression GO:0010467 412 0.078
cellular nitrogen compound biosynthetic process GO:0044271 192 0.076
regulation of developmental growth GO:0048638 389 0.075
transcription from rna polymerase ii promoter GO:0006366 149 0.073
determination of adult lifespan GO:0008340 812 0.072
cellular macromolecule biosynthetic process GO:0034645 247 0.071
single organism reproductive process GO:0044702 1196 0.071
death GO:0016265 547 0.070
purine ribonucleotide metabolic process GO:0009150 95 0.070
macromolecular complex subunit organization GO:0043933 320 0.070
meiotic nuclear division GO:0007126 300 0.069
hermaphrodite genitalia development GO:0040035 734 0.068
response to abiotic stimulus GO:0009628 152 0.067
Fly
negative regulation of metabolic process GO:0009892 240 0.066
macromolecule biosynthetic process GO:0009059 250 0.066
programmed cell death GO:0012501 500 0.066
positive regulation of cellular metabolic process GO:0031325 178 0.065
regulation of gene expression GO:0010468 366 0.064
regulation of cell cycle GO:0051726 194 0.064
regulation of multicellular organismal development GO:2000026 317 0.061
regulation of transcription dna templated GO:0006355 164 0.061
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.061
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.060
multi organism reproductive process GO:0044703 867 0.059
regulation of biological quality GO:0065008 741 0.059
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.058
lipid localization GO:0010876 573 0.057
sexual reproduction GO:0019953 546 0.057
macromolecule localization GO:0033036 771 0.056
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.056
nucleic acid metabolic process GO:0090304 299 0.056
regulation of cell cycle process GO:0010564 145 0.056
developmental process involved in reproduction GO:0003006 1165 0.056
lipid storage GO:0019915 565 0.054
purine nucleoside metabolic process GO:0042278 92 0.054
organonitrogen compound metabolic process GO:1901564 151 0.054
growth GO:0040007 562 0.054
maintenance of location GO:0051235 580 0.052
cellular component movement GO:0006928 388 0.051
cellular response to dna damage stimulus GO:0006974 41 0.051
regulation of growth GO:0040008 409 0.051
purine nucleotide catabolic process GO:0006195 75 0.051
organelle organization GO:0006996 783 0.049
rna interference GO:0016246 137 0.048
aging GO:0007568 812 0.046
posttranscriptional gene silencing by rna GO:0035194 143 0.046
positive regulation of epithelial cell proliferation GO:0050679 1 0.045
gene silencing GO:0016458 143 0.044
positive regulation of macromolecule metabolic process GO:0010604 149 0.044
positive regulation of cellular process GO:0048522 332 0.044
receptor mediated endocytosis GO:0006898 715 0.043
posttranscriptional gene silencing GO:0016441 143 0.043
developmental growth GO:0048589 412 0.042
cellular biosynthetic process GO:0044249 315 0.042
nucleobase containing small molecule metabolic process GO:0055086 115 0.041
neuron development GO:0048666 199 0.041
regulation of metabolic process GO:0019222 478 0.041
purine containing compound catabolic process GO:0072523 75 0.041
multicellular organism growth GO:0035264 385 0.041
glycosyl compound metabolic process GO:1901657 100 0.040
regulation of meiotic cell cycle GO:0051445 136 0.040
regulation of primary metabolic process GO:0080090 292 0.040
tube morphogenesis GO:0035239 79 0.040
cell migration GO:0016477 306 0.040
meiotic cell cycle GO:0051321 335 0.039
post embryonic development GO:0009791 2152 0.038
regulation of macromolecule biosynthetic process GO:0010556 189 0.038
establishment of localization in cell GO:0051649 318 0.038
regulation of response to stimulus GO:0048583 243 0.037
heterocycle biosynthetic process GO:0018130 187 0.037
reproductive behavior GO:0019098 387 0.037
mapk cascade GO:0000165 31 0.037
regulation of developmental process GO:0050793 684 0.036
positive regulation of multicellular organism growth GO:0040018 352 0.036
regulation of cell proliferation GO:0042127 105 0.036
negative regulation of macromolecule metabolic process GO:0010605 229 0.036
multicellular organismal reproductive behavior GO:0033057 384 0.036
nucleoside phosphate catabolic process GO:1901292 77 0.035
small molecule metabolic process GO:0044281 186 0.034
protein modification process GO:0036211 207 0.034
positive regulation of developmental process GO:0051094 408 0.034
biosynthetic process GO:0009058 323 0.034
cellular component assembly GO:0022607 293 0.033
organic substance catabolic process GO:1901575 294 0.033
multi organism reproductive behavior GO:0044705 387 0.032
transcription dna templated GO:0006351 168 0.032
multi multicellular organism process GO:0044706 390 0.032
organonitrogen compound catabolic process GO:1901565 90 0.032
regulation of multicellular organism growth GO:0040014 373 0.031
nucleobase containing compound biosynthetic process GO:0034654 184 0.031
localization of cell GO:0051674 313 0.031
cellular macromolecular complex assembly GO:0034622 184 0.031
cellular component biogenesis GO:0044085 297 0.031
nucleoside triphosphate metabolic process GO:0009141 87 0.031
organic cyclic compound biosynthetic process GO:1901362 195 0.031
positive regulation of metabolic process GO:0009893 187 0.031
positive regulation of multicellular organismal process GO:0051240 417 0.030
cell motility GO:0048870 313 0.030
single organism transport GO:0044765 447 0.030
regulation of behavior GO:0050795 97 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.030
regulation of cellular metabolic process GO:0031323 305 0.029
aromatic compound biosynthetic process GO:0019438 192 0.029
multi organism behavior GO:0051705 389 0.029
ribonucleoside metabolic process GO:0009119 98 0.029
regulation of rna biosynthetic process GO:2001141 165 0.029
cellular protein modification process GO:0006464 207 0.029
nucleotide metabolic process GO:0009117 108 0.029
purine containing compound metabolic process GO:0072521 95 0.028
ribonucleoside catabolic process GO:0042454 77 0.028
cell proliferation GO:0008283 116 0.028
oviposition GO:0018991 364 0.028
nucleoside monophosphate metabolic process GO:0009123 46 0.028
nucleoside metabolic process GO:0009116 99 0.028
nervous system development GO:0007399 253 0.028
regulation of nucleic acid templated transcription GO:1903506 165 0.028
neurogenesis GO:0022008 236 0.027
macromolecule modification GO:0043412 218 0.027
ribonucleoside triphosphate metabolic process GO:0009199 87 0.027
response to temperature stimulus GO:0009266 66 0.027
positive regulation of growth GO:0045927 369 0.027
ribonucleoside triphosphate catabolic process GO:0009203 72 0.027
rna biosynthetic process GO:0032774 169 0.026
cell cycle process GO:0022402 482 0.026
nucleobase containing compound catabolic process GO:0034655 114 0.026
regulation of biosynthetic process GO:0009889 189 0.025
digestive tract development GO:0048565 122 0.025
nucleoside catabolic process GO:0009164 78 0.024
generation of neurons GO:0048699 235 0.024
glycosyl compound catabolic process GO:1901658 79 0.024
nucleoside phosphate metabolic process GO:0006753 108 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.024
regulation of localization GO:0032879 194 0.023
nucleotide catabolic process GO:0009166 77 0.023
body morphogenesis GO:0010171 620 0.023
regulation of cell communication GO:0010646 176 0.022
gamete generation GO:0007276 461 0.022
positive regulation of developmental growth GO:0048639 354 0.022
purine nucleoside catabolic process GO:0006152 75 0.022
positive regulation of rna metabolic process GO:0051254 103 0.022
protein metabolic process GO:0019538 422 0.022
muscle tissue development GO:0060537 1 0.022
posttranscriptional regulation of gene expression GO:0010608 166 0.022
purine nucleotide metabolic process GO:0006163 95 0.021
regulation of cell differentiation GO:0045595 81 0.021
single organism organelle organization GO:1902589 501 0.021
organ morphogenesis GO:0009887 67 0.021
organophosphate metabolic process GO:0019637 125 0.021
gene silencing by rna GO:0031047 143 0.020
apoptotic process GO:0006915 478 0.020
regulation of molecular function GO:0065009 89 0.020
regulation of gene expression epigenetic GO:0040029 163 0.020
negative regulation of neurogenesis GO:0050768 4 0.020
neuron differentiation GO:0030182 217 0.020
single organism catabolic process GO:0044712 129 0.020
carbohydrate derivative metabolic process GO:1901135 141 0.019
ribonucleoside monophosphate catabolic process GO:0009158 28 0.019
positive regulation of gene expression GO:0010628 112 0.019
ribonucleoside monophosphate metabolic process GO:0009161 45 0.019
cellular component morphogenesis GO:0032989 318 0.019
single organism carbohydrate metabolic process GO:0044723 29 0.018
negative regulation of response to stimulus GO:0048585 73 0.018
muscle structure development GO:0061061 191 0.018
aromatic compound catabolic process GO:0019439 116 0.018
purine ribonucleoside metabolic process GO:0046128 92 0.018
ribonucleotide catabolic process GO:0009261 75 0.018
single organism localization GO:1902578 518 0.018
carbohydrate derivative catabolic process GO:1901136 82 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.017
purine nucleoside monophosphate catabolic process GO:0009128 28 0.017
canonical wnt signaling pathway GO:0060070 3 0.017
ribonucleotide metabolic process GO:0009259 99 0.016
positive regulation of cellular biosynthetic process GO:0031328 109 0.016
positive regulation of cellular protein catabolic process GO:1903364 3 0.016
organophosphate catabolic process GO:0046434 81 0.016
signaling GO:0023052 401 0.016
positive regulation of molecular function GO:0044093 61 0.016
cellular protein metabolic process GO:0044267 279 0.016
cellular ketone metabolic process GO:0042180 14 0.016
inductive cell migration GO:0040039 145 0.016
oogenesis GO:0048477 229 0.016
negative regulation of cellular metabolic process GO:0031324 95 0.016
cell division GO:0051301 262 0.016
positive regulation of protein metabolic process GO:0051247 45 0.016
digestive system development GO:0055123 122 0.016
negative regulation of cell cycle GO:0045786 53 0.015
regulation of cell death GO:0010941 65 0.015
regulation of apoptotic signaling pathway GO:2001233 1 0.015
negative regulation of cellular biosynthetic process GO:0031327 65 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.015
response to wounding GO:0009611 4 0.015
negative regulation of cellular process GO:0048523 239 0.015
regulation of locomotion GO:0040012 161 0.014
positive regulation of protein modification process GO:0031401 29 0.014
regulation of signaling GO:0023051 172 0.014
heterocycle catabolic process GO:0046700 119 0.014
cell type specific apoptotic process GO:0097285 4 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.014
atp catabolic process GO:0006200 27 0.013
purine nucleoside monophosphate metabolic process GO:0009126 43 0.013
dendrite development GO:0016358 42 0.013
nucleoside triphosphate catabolic process GO:0009143 72 0.013
positive regulation of catalytic activity GO:0043085 59 0.013
organic cyclic compound catabolic process GO:1901361 119 0.013
negative regulation of cell communication GO:0010648 61 0.012
response to chemical GO:0042221 356 0.012
negative regulation of mitotic cell cycle GO:0045930 42 0.012
regulation of epithelial cell proliferation GO:0050678 1 0.012
negative regulation of organ growth GO:0046621 1 0.012
regulation of cellular component organization GO:0051128 248 0.012
cellular catabolic process GO:0044248 199 0.012
negative regulation of bmp signaling pathway GO:0030514 1 0.011
response to organic substance GO:0010033 131 0.011
homeostatic process GO:0042592 51 0.011
organelle fission GO:0048285 363 0.011
positive regulation of biosynthetic process GO:0009891 109 0.011
atp metabolic process GO:0046034 42 0.011
purine ribonucleotide catabolic process GO:0009154 75 0.011
myofibril assembly GO:0030239 154 0.010
regulation of vesicle mediated transport GO:0060627 27 0.010
feeding behavior GO:0007631 70 0.010
neuron projection morphogenesis GO:0048812 114 0.010
neuron projection development GO:0031175 187 0.010
positive regulation of proteasomal protein catabolic process GO:1901800 1 0.010
cell part morphogenesis GO:0032990 152 0.010
carboxylic acid metabolic process GO:0019752 34 0.010
regulation of reproductive process GO:2000241 66 0.010
defense response GO:0006952 296 0.010
deoxyribonucleotide biosynthetic process GO:0009263 1 0.010

gen-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
disease of anatomical entity DOID:7 0 0.010
nervous system disease DOID:863 0 0.010