Caenorhabditis elegans

56 known processes

icd-1 (CELE_C56C10.8)

Protein ICD-1

icd-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.975
embryo development ending in birth or egg hatching GO:0009792 2992 0.968
establishment of localization GO:0051234 1171 0.875
cell death GO:0008219 547 0.852
transport GO:0006810 1093 0.830
endocytosis GO:0006897 819 0.824
multicellular organismal reproductive process GO:0048609 815 0.823
Fly
sexual reproduction GO:0019953 546 0.822
Fly
cell migration GO:0016477 306 0.814
developmental process involved in reproduction GO:0003006 1165 0.782
hermaphrodite genitalia development GO:0040035 734 0.772
multicellular organism reproduction GO:0032504 819 0.766
Fly
organelle organization GO:0006996 783 0.753
cell motility GO:0048870 313 0.698
single organism reproductive process GO:0044702 1196 0.681
gonad development GO:0008406 840 0.668
cellular component movement GO:0006928 388 0.621
vesicle mediated transport GO:0016192 852 0.610
post embryonic development GO:0009791 2152 0.596
locomotion GO:0040011 1634 0.593
female gamete generation GO:0007292 254 0.592
Fly
reproductive system development GO:0061458 850 0.587
inductive cell migration GO:0040039 145 0.577
sex differentiation GO:0007548 909 0.576
oocyte construction GO:0007308 2 0.541
Fly
receptor mediated endocytosis GO:0006898 715 0.538
gamete generation GO:0007276 461 0.538
Fly
reproductive structure development GO:0048608 850 0.528
development of primary sexual characteristics GO:0045137 840 0.516
apoptotic process GO:0006915 478 0.505
localization of cell GO:0051674 313 0.493
ribosome biogenesis GO:0042254 4 0.490
death GO:0016265 547 0.483
oogenesis GO:0048477 229 0.480
Fly
gene expression GO:0010467 412 0.477
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.469
Fly
multicellular organismal aging GO:0010259 812 0.460
cell cycle GO:0007049 526 0.451
genitalia development GO:0048806 741 0.424
aging GO:0007568 812 0.413
organ development GO:0048513 1102 0.409
regulation of gene expression GO:0010468 366 0.404
oocyte axis specification GO:0007309 2 0.396
Fly
negative regulation of biological process GO:0048519 567 0.380
determination of adult lifespan GO:0008340 812 0.374
regulation of cellular biosynthetic process GO:0031326 189 0.372
protein metabolic process GO:0019538 422 0.369
cellular component assembly GO:0022607 293 0.365
Fly
positive regulation of cellular biosynthetic process GO:0031328 109 0.364
regulation of metabolic process GO:0019222 478 0.357
positive regulation of cellular process GO:0048522 332 0.350
protein complex subunit organization GO:0071822 280 0.330
positive regulation of metabolic process GO:0009893 187 0.315
organic substance biosynthetic process GO:1901576 323 0.309
multi organism reproductive process GO:0044703 867 0.308
Fly
regulation of macromolecule metabolic process GO:0060255 421 0.302
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.292
positive regulation of macromolecule metabolic process GO:0010604 149 0.289
cellular localization GO:0051641 360 0.283
Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.279
single organism organelle organization GO:1902589 501 0.273
signaling GO:0023052 401 0.273
regulation of multicellular organismal process GO:0051239 726 0.264
Fly
nervous system development GO:0007399 253 0.262
positive regulation of biosynthetic process GO:0009891 109 0.249
cellular nitrogen compound biosynthetic process GO:0044271 192 0.247
cellular protein metabolic process GO:0044267 279 0.236
meiotic cell cycle GO:0051321 335 0.226
positive regulation of cellular metabolic process GO:0031325 178 0.225
cellular biosynthetic process GO:0044249 315 0.223
positive regulation of nucleic acid templated transcription GO:1903508 102 0.221
biosynthetic process GO:0009058 323 0.209
cellular component biogenesis GO:0044085 297 0.208
Fly
mitotic cell cycle process GO:1903047 194 0.206
programmed cell death GO:0012501 500 0.204
cellular macromolecule biosynthetic process GO:0034645 247 0.203
organelle assembly GO:0070925 214 0.203
cell development GO:0048468 696 0.203
Fly
single fertilization GO:0007338 61 0.201
oocyte development GO:0048599 44 0.200
Fly
meiotic nuclear division GO:0007126 300 0.199
pole plasm assembly GO:0007315 2 0.193
Fly
body morphogenesis GO:0010171 620 0.192
germ cell development GO:0007281 351 0.188
Fly
macromolecular complex subunit organization GO:0043933 320 0.184
regulation of signaling GO:0023051 172 0.182
positive regulation of rna biosynthetic process GO:1902680 102 0.181
phosphorus metabolic process GO:0006793 232 0.175
nucleic acid metabolic process GO:0090304 299 0.172
nucleic acid templated transcription GO:0097659 169 0.171
positive regulation of transcription dna templated GO:0045893 102 0.168
regulation of nitrogen compound metabolic process GO:0051171 222 0.167
organelle fission GO:0048285 363 0.167
microtubule based process GO:0007017 182 0.164
neurogenesis GO:0022008 236 0.164
cell cycle process GO:0022402 482 0.157
positive regulation of gene expression GO:0010628 112 0.150
protein catabolic process GO:0030163 162 0.148
cellular protein modification process GO:0006464 207 0.147
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.131
growth GO:0040007 562 0.131
negative regulation of cellular process GO:0048523 239 0.131
meiotic chromosome segregation GO:0045132 139 0.131
regulation of cell cycle GO:0051726 194 0.129
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.129
regulation of cellular metabolic process GO:0031323 305 0.128
positive regulation of rna metabolic process GO:0051254 103 0.126
macromolecule localization GO:0033036 771 0.125
Fly
protein modification process GO:0036211 207 0.124
ribonucleoprotein complex assembly GO:0022618 4 0.124
rna metabolic process GO:0016070 228 0.123
nucleobase containing compound metabolic process GO:0006139 406 0.121
heterocycle biosynthetic process GO:0018130 187 0.121
multicellular organismal reproductive behavior GO:0033057 384 0.121
regulation of developmental process GO:0050793 684 0.121
Fly
regulation of rna biosynthetic process GO:2001141 165 0.120
regulation of primary metabolic process GO:0080090 292 0.118
cytoskeleton organization GO:0007010 339 0.115
protein complex assembly GO:0006461 186 0.115
macromolecule biosynthetic process GO:0009059 250 0.113
chromosome organization GO:0051276 104 0.111
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.106
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.105
phosphate containing compound metabolic process GO:0006796 232 0.104
single organism transport GO:0044765 447 0.103
establishment of localization in cell GO:0051649 318 0.103
rna biosynthetic process GO:0032774 169 0.102
protein phosphorylation GO:0006468 85 0.102
fertilization GO:0009566 63 0.100
organic cyclic compound biosynthetic process GO:1901362 195 0.100
macromolecular complex assembly GO:0065003 193 0.099
regulation of meiotic cell cycle GO:0051445 136 0.099
macromolecule modification GO:0043412 218 0.097
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.097
male gamete generation GO:0048232 41 0.097
response to external stimulus GO:0009605 289 0.096
positive regulation of developmental growth GO:0048639 354 0.095
phosphorylation GO:0016310 116 0.095
response to abiotic stimulus GO:0009628 152 0.094
regulation of biological quality GO:0065008 741 0.093
negative regulation of metabolic process GO:0009892 240 0.092
oocyte differentiation GO:0009994 45 0.091
Fly
lipid localization GO:0010876 573 0.090
regulation of catalytic activity GO:0050790 78 0.090
nucleobase containing compound biosynthetic process GO:0034654 184 0.088
transcription dna templated GO:0006351 168 0.086
single organism signaling GO:0044700 401 0.085
meiotic cell cycle process GO:1903046 170 0.084
regulation of cellular component organization GO:0051128 248 0.083
Fly
anatomical structure formation involved in morphogenesis GO:0048646 250 0.083
developmental growth GO:0048589 412 0.081
regulation of macromolecule biosynthetic process GO:0010556 189 0.081
positive regulation of growth GO:0045927 369 0.081
regulation of growth GO:0040008 409 0.078
regulation of response to stimulus GO:0048583 243 0.078
spermatogenesis GO:0007283 41 0.077
cellular macromolecular complex assembly GO:0034622 184 0.075
dauer larval development GO:0040024 92 0.075
regulation of cell differentiation GO:0045595 81 0.074
Fly
positive regulation of multicellular organismal process GO:0051240 417 0.073
maintenance of location GO:0051235 580 0.072
generation of neurons GO:0048699 235 0.072
molting cycle GO:0042303 281 0.071
regulation of biosynthetic process GO:0009889 189 0.071
cellular component morphogenesis GO:0032989 318 0.070
rna localization GO:0006403 3 0.070
Fly
lipid storage GO:0019915 565 0.070
positive regulation of developmental process GO:0051094 408 0.070
negative regulation of macromolecule metabolic process GO:0010605 229 0.068
intracellular signal transduction GO:0035556 96 0.068
regulation of localization GO:0032879 194 0.066
Fly
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.063
signal transduction GO:0007165 317 0.062
regulation of apoptotic process GO:0042981 36 0.060
regulation of signal transduction GO:0009966 135 0.060
centrosomal and pronuclear rotation GO:0035047 6 0.060
negative regulation of gene expression GO:0010629 217 0.060
regulation of nucleic acid templated transcription GO:1903506 165 0.059
regulation of multicellular organism growth GO:0040014 373 0.058
catabolic process GO:0009056 318 0.057
positive regulation of multicellular organism growth GO:0040018 352 0.057
pronuclear migration GO:0035046 51 0.057
regulation of developmental growth GO:0048638 389 0.056
response to chemical GO:0042221 356 0.056
cell proliferation GO:0008283 116 0.055
single organism localization GO:1902578 518 0.054
Fly
aromatic compound biosynthetic process GO:0019438 192 0.054
taxis GO:0042330 128 0.054
spindle organization GO:0007051 92 0.053
transcription from rna polymerase ii promoter GO:0006366 149 0.053
multicellular organism growth GO:0035264 385 0.053
oviposition GO:0018991 364 0.052
regulation of cell division GO:0051302 142 0.051
regulation of cell proliferation GO:0042127 105 0.051
protein complex biogenesis GO:0070271 186 0.051
behavior GO:0007610 527 0.051
regulation of transcription dna templated GO:0006355 164 0.050
cellular response to stress GO:0033554 162 0.049
establishment or maintenance of cell polarity GO:0007163 63 0.048
tissue development GO:0009888 112 0.047
cell division GO:0051301 262 0.046
regulation of rna metabolic process GO:0051252 173 0.046
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.046
regulation of protein metabolic process GO:0051246 81 0.045
regulation of apoptotic signaling pathway GO:2001233 1 0.045
muscle cell differentiation GO:0042692 171 0.044
cellular protein complex assembly GO:0043623 178 0.044
positive regulation of signal transduction GO:0009967 40 0.044
negative regulation of apoptotic process GO:0043066 17 0.043
regulation of cell communication GO:0010646 176 0.042
cell morphogenesis GO:0000902 163 0.041
cellular macromolecule localization GO:0070727 75 0.041
Fly
regulation of cellular protein metabolic process GO:0032268 75 0.040
actin cytoskeleton organization GO:0030036 184 0.040
protein localization GO:0008104 205 0.039
Fly
neuron differentiation GO:0030182 217 0.039
single organism cellular localization GO:1902580 72 0.039
Fly
axis specification GO:0009798 23 0.039
Fly
phagocytosis GO:0006909 115 0.038
muscle structure development GO:0061061 191 0.038
gene silencing by rna GO:0031047 143 0.038
response to wounding GO:0009611 4 0.037
organic substance catabolic process GO:1901575 294 0.037
mitotic nuclear division GO:0007067 89 0.035
regulation of nucleocytoplasmic transport GO:0046822 3 0.034
cellular ketone metabolic process GO:0042180 14 0.034
cell type specific apoptotic process GO:0097285 4 0.033
posttranscriptional gene silencing by rna GO:0035194 143 0.033
defense response GO:0006952 296 0.033
cell projection organization GO:0030030 231 0.033
negative regulation of transcription dna templated GO:0045892 53 0.033
peptidyl amino acid modification GO:0018193 58 0.032
multi organism behavior GO:0051705 389 0.032
reproductive behavior GO:0019098 387 0.032
chemotaxis GO:0006935 120 0.032
regulation of phosphate metabolic process GO:0019220 81 0.032
nucleotide metabolic process GO:0009117 108 0.031
positive regulation of phosphate metabolic process GO:0045937 56 0.031
striated muscle cell development GO:0055002 157 0.030
regulation of cell death GO:0010941 65 0.029
posttranscriptional regulation of gene expression GO:0010608 166 0.029
small molecule metabolic process GO:0044281 186 0.029
head development GO:0060322 1 0.029
macromolecule catabolic process GO:0009057 202 0.028
negative regulation of cellular metabolic process GO:0031324 95 0.028
mitotic spindle organization GO:0007052 81 0.028
muscle cell development GO:0055001 158 0.028
single organism biosynthetic process GO:0044711 91 0.028
response to temperature stimulus GO:0009266 66 0.028
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.028
muscle tissue development GO:0060537 1 0.027
response to organic substance GO:0010033 131 0.027
regulation of meiosis GO:0040020 94 0.027
regulation of programmed cell death GO:0043067 50 0.027
membrane organization GO:0061024 135 0.026
regulation of epithelial cell proliferation GO:0050678 1 0.026
rrna metabolic process GO:0016072 3 0.026
positive regulation of molecular function GO:0044093 61 0.026
chromosome segregation GO:0007059 180 0.025
organonitrogen compound metabolic process GO:1901564 151 0.025
cellular catabolic process GO:0044248 199 0.025
regulation of gene expression epigenetic GO:0040029 163 0.025
single organism intracellular transport GO:1902582 70 0.025
cellular component assembly involved in morphogenesis GO:0010927 183 0.024
protein refolding GO:0042026 1 0.024
positive regulation of cell communication GO:0010647 69 0.024
regulation of protein localization GO:0032880 50 0.024
Fly
intracellular transport GO:0046907 77 0.024
actomyosin structure organization GO:0031032 154 0.024
regulation of intracellular signal transduction GO:1902531 77 0.024
developmental maturation GO:0021700 26 0.023
Fly
multi multicellular organism process GO:0044706 390 0.023
organic substance transport GO:0071702 113 0.023
neuron development GO:0048666 199 0.023
purine nucleoside metabolic process GO:0042278 92 0.023
digestive tract morphogenesis GO:0048546 76 0.023
negative regulation of cell communication GO:0010648 61 0.022
cell part morphogenesis GO:0032990 152 0.022
regulation of mitotic cell cycle GO:0007346 76 0.022
establishment of organelle localization GO:0051656 123 0.022
regulation of multicellular organismal development GO:2000026 317 0.022
Fly
rna interference GO:0016246 137 0.022
organophosphate metabolic process GO:0019637 125 0.022
negative regulation of cell death GO:0060548 21 0.021
phagocytosis engulfment GO:0006911 98 0.021
mating GO:0007618 34 0.021
posttranscriptional gene silencing GO:0016441 143 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
positive regulation of response to stimulus GO:0048584 55 0.021
cellular response to chemical stimulus GO:0070887 129 0.021
actin filament based process GO:0030029 191 0.021
regulation of molecular function GO:0065009 89 0.021
cell maturation GO:0048469 26 0.021
Fly
cell surface receptor signaling pathway GO:0007166 149 0.020
chromatin organization GO:0006325 32 0.020
skeletal muscle organ development GO:0060538 3 0.020
positive regulation of ras protein signal transduction GO:0046579 7 0.020
organ morphogenesis GO:0009887 67 0.020
regulation of response to wounding GO:1903034 1 0.020
purine containing compound metabolic process GO:0072521 95 0.020
translation GO:0006412 37 0.020
oxoacid metabolic process GO:0043436 47 0.019
regionalization GO:0003002 31 0.019
Fly
protein transmembrane transport GO:0071806 4 0.019
negative regulation of response to stimulus GO:0048585 73 0.019
negative regulation of signaling GO:0023057 61 0.019
protein targeting to mitochondrion GO:0006626 2 0.019
neuron projection guidance GO:0097485 82 0.019
cellular protein localization GO:0034613 75 0.019
cellular response to organic substance GO:0071310 119 0.019
regulation of phosphorus metabolic process GO:0051174 81 0.019
purine nucleotide metabolic process GO:0006163 95 0.019
multi organism reproductive behavior GO:0044705 387 0.019
myofibril assembly GO:0030239 154 0.019
proteolysis GO:0006508 61 0.019
male sex differentiation GO:0046661 86 0.018
cellular amino acid metabolic process GO:0006520 15 0.018
organic acid metabolic process GO:0006082 47 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.018
signal transduction by phosphorylation GO:0023014 31 0.018
negative regulation of rna metabolic process GO:0051253 53 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.018
immune response GO:0006955 192 0.018
positive regulation of phosphorus metabolic process GO:0010562 56 0.018
gene silencing GO:0016458 143 0.017
single organism catabolic process GO:0044712 129 0.017
purine nucleoside triphosphate catabolic process GO:0009146 72 0.017
cellular response to abiotic stimulus GO:0071214 4 0.017
regulation of cell cycle process GO:0010564 145 0.017
negative regulation of programmed cell death GO:0043069 19 0.017
intracellular receptor signaling pathway GO:0030522 2 0.017
positive regulation of cell migration GO:0030335 3 0.016
collagen and cuticulin based cuticle development GO:0040002 99 0.016
response to hermaphrodite contact GO:0034606 10 0.016
negative regulation of signal transduction GO:0009968 60 0.016
striated muscle myosin thick filament assembly GO:0071688 138 0.016
negative regulation of cellular biosynthetic process GO:0031327 65 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
myosin filament organization GO:0031033 138 0.016
anterior posterior axis specification GO:0009948 17 0.016
Fly
negative regulation of mitotic cell cycle GO:0045930 42 0.016
regulation of transport GO:0051049 91 0.016
regulation of organ morphogenesis GO:2000027 4 0.015
hermaphrodite germ line sex determination GO:0040021 48 0.015
rrna processing GO:0006364 3 0.015
cellular amine metabolic process GO:0044106 15 0.015
cell projection morphogenesis GO:0048858 148 0.015
nucleobase containing small molecule metabolic process GO:0055086 115 0.015
mating behavior GO:0007617 32 0.015
establishment of protein localization to mitochondrion GO:0072655 2 0.015
negative regulation of biosynthetic process GO:0009890 65 0.015
neuron projection development GO:0031175 187 0.015
positive regulation of signaling GO:0023056 66 0.015
mitochondrion organization GO:0007005 20 0.014
regulation of organelle organization GO:0033043 164 0.014
purine nucleoside triphosphate metabolic process GO:0009144 87 0.014
cell morphogenesis involved in differentiation GO:0000904 112 0.014
nucleoside phosphate metabolic process GO:0006753 108 0.014
embryonic pattern specification GO:0009880 21 0.014
Fly
system process GO:0003008 136 0.014
positive regulation of catalytic activity GO:0043085 59 0.014
myosin filament assembly GO:0031034 138 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.014
vulval development GO:0040025 333 0.014
response to topologically incorrect protein GO:0035966 82 0.014
cell fate commitment GO:0045165 139 0.014
amine metabolic process GO:0009308 15 0.014
oxidation reduction process GO:0055114 59 0.014
response to external biotic stimulus GO:0043207 101 0.014
response to heat GO:0009408 50 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.013
small gtpase mediated signal transduction GO:0007264 32 0.013
organelle localization GO:0051640 127 0.013
ribose phosphate metabolic process GO:0019693 99 0.013
positive regulation of protein metabolic process GO:0051247 45 0.013
nucleoside triphosphate metabolic process GO:0009141 87 0.013
cuticle development GO:0042335 100 0.013
cellular macromolecule catabolic process GO:0044265 73 0.013
regulation of cellular component movement GO:0051270 62 0.013
single organism behavior GO:0044708 83 0.013
epithelial cell proliferation GO:0050673 1 0.013
embryonic morphogenesis GO:0048598 152 0.013
response to other organism GO:0051707 101 0.012
epithelium development GO:0060429 68 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.012
purine ribonucleotide metabolic process GO:0009150 95 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
protein oligomerization GO:0051259 4 0.012
regulation of protein targeting GO:1903533 3 0.012
histone modification GO:0016570 30 0.012
modification dependent protein catabolic process GO:0019941 32 0.012
membrane invagination GO:0010324 98 0.012
nucleoside metabolic process GO:0009116 99 0.012
positive regulation of epithelial cell proliferation GO:0050679 1 0.011
axonogenesis GO:0007409 102 0.011
regulation of hydrolase activity GO:0051336 45 0.011
regulation of cell development GO:0060284 49 0.011
Fly
negative regulation of neurogenesis GO:0050768 4 0.011
cellular nitrogen compound catabolic process GO:0044270 119 0.011
apoptotic cell clearance GO:0043277 111 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.011
chromatin remodeling GO:0006338 2 0.011
negative regulation of cell cycle GO:0045786 53 0.011
establishment of nucleus localization GO:0040023 55 0.011
regulation of response to stress GO:0080134 28 0.011
response to biotic stimulus GO:0009607 101 0.011
axon development GO:0061564 163 0.011
digestive tract development GO:0048565 122 0.011
carbohydrate derivative metabolic process GO:1901135 141 0.010
innate immune response GO:0045087 190 0.010
glycosyl compound metabolic process GO:1901657 100 0.010
negative regulation of developmental process GO:0051093 227 0.010
dna templated transcription initiation GO:0006352 3 0.010
response to bacterium GO:0009617 86 0.010
regulation of protein import into nucleus GO:0042306 3 0.010
ribonucleoside metabolic process GO:0009119 98 0.010
protein targeting GO:0006605 10 0.010
cell cycle g1 s phase transition GO:0044843 2 0.010
small molecule biosynthetic process GO:0044283 38 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
carboxylic acid metabolic process GO:0019752 34 0.010
axon guidance GO:0007411 82 0.010

icd-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.011