Caenorhabditis elegans

12 known processes

sdha-1 (CELE_C03G5.1)

Protein SDHA-1

sdha-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.666
transport GO:0006810 1093 0.444
post embryonic development GO:0009791 2152 0.422
Worm
establishment of localization GO:0051234 1171 0.322
locomotion GO:0040011 1634 0.304
signaling GO:0023052 401 0.265
embryo development ending in birth or egg hatching GO:0009792 2992 0.232
single organism signaling GO:0044700 401 0.209
establishment of localization in cell GO:0051649 318 0.204
single organism transport GO:0044765 447 0.186
single organism reproductive process GO:0044702 1196 0.185
vesicle mediated transport GO:0016192 852 0.174
muscle cell differentiation GO:0042692 171 0.172
regulation of signaling GO:0023051 172 0.165
cellular response to chemical stimulus GO:0070887 129 0.163
response to organic substance GO:0010033 131 0.157
cellular localization GO:0051641 360 0.155
single organism localization GO:1902578 518 0.144
cell development GO:0048468 696 0.138
secretion GO:0046903 147 0.135
cellular nitrogen compound biosynthetic process GO:0044271 192 0.133
positive regulation of cellular process GO:0048522 332 0.131
aging GO:0007568 812 0.131
body morphogenesis GO:0010171 620 0.129
female gamete generation GO:0007292 254 0.120
cell cell signaling GO:0007267 118 0.118
endocytosis GO:0006897 819 0.113
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.110
regulation of biological quality GO:0065008 741 0.110
determination of adult lifespan GO:0008340 812 0.110
multicellular organism reproduction GO:0032504 819 0.108
Worm
gamete generation GO:0007276 461 0.104
actin filament based process GO:0030029 191 0.103
macromolecule localization GO:0033036 771 0.102
protein metabolic process GO:0019538 422 0.102
multicellular organismal aging GO:0010259 812 0.102
muscle structure development GO:0061061 191 0.098
cellular component morphogenesis GO:0032989 318 0.097
response to chemical GO:0042221 356 0.097
cellular response to organic substance GO:0071310 119 0.097
organ development GO:0048513 1102 0.094
nucleobase containing compound metabolic process GO:0006139 406 0.093
head development GO:0060322 1 0.092
ion transport GO:0006811 113 0.091
synaptic transmission GO:0007268 106 0.090
positive regulation of multicellular organismal process GO:0051240 417 0.089
striated muscle cell differentiation GO:0051146 158 0.089
regulation of developmental process GO:0050793 684 0.088
negative regulation of biological process GO:0048519 567 0.087
single organism organelle organization GO:1902589 501 0.085
regulation of multicellular organismal process GO:0051239 726 0.084
germ cell development GO:0007281 351 0.083
positive regulation of macromolecule metabolic process GO:0010604 149 0.083
cellular macromolecule biosynthetic process GO:0034645 247 0.082
macromolecular complex subunit organization GO:0043933 320 0.082
sexual reproduction GO:0019953 546 0.081
cellular biosynthetic process GO:0044249 315 0.081
multicellular organismal reproductive process GO:0048609 815 0.080
Worm
biosynthetic process GO:0009058 323 0.079
actin cytoskeleton organization GO:0030036 184 0.079
organic substance biosynthetic process GO:1901576 323 0.072
positive regulation of locomotion GO:0040017 42 0.072
secretion by cell GO:0032940 138 0.071
positive regulation of intracellular transport GO:0032388 2 0.071
organonitrogen compound metabolic process GO:1901564 151 0.071
response to endogenous stimulus GO:0009719 33 0.071
striated muscle cell development GO:0055002 157 0.070
organelle organization GO:0006996 783 0.070
regulation of cell communication GO:0010646 176 0.069
system process GO:0003008 136 0.069
cellular response to endogenous stimulus GO:0071495 32 0.068
cytoskeleton organization GO:0007010 339 0.068
death GO:0016265 547 0.068
regulation of growth GO:0040008 409 0.067
negative regulation of multicellular organismal process GO:0051241 236 0.066
developmental process involved in reproduction GO:0003006 1165 0.066
maintenance of location GO:0051235 580 0.065
cellular component movement GO:0006928 388 0.063
gene expression GO:0010467 412 0.063
signal transduction GO:0007165 317 0.063
negative regulation of nematode larval development GO:0061064 208 0.063
negative regulation of cellular process GO:0048523 239 0.063
regulation of macromolecule metabolic process GO:0060255 421 0.062
organelle assembly GO:0070925 214 0.062
regulation of metabolic process GO:0019222 478 0.062
skeletal muscle organ development GO:0060538 3 0.061
regulation of cellular localization GO:0060341 42 0.061
phosphorus metabolic process GO:0006793 232 0.061
regulation of locomotion GO:0040012 161 0.060
lipid storage GO:0019915 565 0.059
regulation of response to stimulus GO:0048583 243 0.059
lipid localization GO:0010876 573 0.058
energy derivation by oxidation of organic compounds GO:0015980 14 0.058
Human
localization of cell GO:0051674 313 0.056
cell surface receptor signaling pathway GO:0007166 149 0.055
multi organism reproductive process GO:0044703 867 0.055
Worm
multi multicellular organism process GO:0044706 390 0.054
Worm
phosphate containing compound metabolic process GO:0006796 232 0.054
regulation of transport GO:0051049 91 0.053
response to wounding GO:0009611 4 0.052
myosin filament assembly GO:0031034 138 0.052
genitalia development GO:0048806 741 0.052
regulation of gene expression GO:0010468 366 0.051
developmental growth GO:0048589 412 0.050
heterocycle catabolic process GO:0046700 119 0.050
muscle cell development GO:0055001 158 0.050
multicellular organism growth GO:0035264 385 0.050
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.050
apoptotic process GO:0006915 478 0.049
response to external stimulus GO:0009605 289 0.049
regulation of nematode larval development GO:0061062 260 0.049
muscle contraction GO:0006936 43 0.049
cell migration GO:0016477 306 0.048
regulation of cellular component organization GO:0051128 248 0.048
cellular component assembly involved in morphogenesis GO:0010927 183 0.048
regulation of localization GO:0032879 194 0.047
cell motility GO:0048870 313 0.047
positive regulation of growth GO:0045927 369 0.047
embryonic morphogenesis GO:0048598 152 0.047
memory GO:0007613 3 0.047
macromolecule biosynthetic process GO:0009059 250 0.046
muscle tissue development GO:0060537 1 0.046
protein complex subunit organization GO:0071822 280 0.045
myofibril assembly GO:0030239 154 0.045
growth GO:0040007 562 0.045
regulation of developmental growth GO:0048638 389 0.044
hermaphrodite genitalia development GO:0040035 734 0.044
behavior GO:0007610 527 0.044
Worm
positive regulation of developmental growth GO:0048639 354 0.044
multicellular organismal reproductive behavior GO:0033057 384 0.043
Worm
receptor mediated endocytosis GO:0006898 715 0.042
reproductive behavior GO:0019098 387 0.042
Worm
protein complex biogenesis GO:0070271 186 0.042
cellular catabolic process GO:0044248 199 0.042
regulation of ion transport GO:0043269 39 0.042
macromolecule catabolic process GO:0009057 202 0.041
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.041
programmed cell death GO:0012501 500 0.041
cell cycle process GO:0022402 482 0.041
catabolic process GO:0009056 318 0.040
glycosyl compound catabolic process GO:1901658 79 0.040
cellular response to hormone stimulus GO:0032870 14 0.040
molting cycle GO:0042303 281 0.040
pattern specification process GO:0007389 59 0.040
actomyosin structure organization GO:0031032 154 0.040
cellular response to inorganic substance GO:0071241 3 0.039
protein localization GO:0008104 205 0.038
organic substance catabolic process GO:1901575 294 0.038
single organism intracellular transport GO:1902582 70 0.038
cellular protein metabolic process GO:0044267 279 0.038
cellular protein modification process GO:0006464 207 0.038
negative regulation of metabolic process GO:0009892 240 0.037
tissue development GO:0009888 112 0.037
sex differentiation GO:0007548 909 0.037
macromolecular complex assembly GO:0065003 193 0.036
negative regulation of response to stimulus GO:0048585 73 0.036
cellular amine metabolic process GO:0044106 15 0.035
response to organonitrogen compound GO:0010243 15 0.035
nucleoside phosphate metabolic process GO:0006753 108 0.035
positive regulation of multicellular organism growth GO:0040018 352 0.035
negative regulation of post embryonic development GO:0048581 208 0.035
anatomical structure formation involved in morphogenesis GO:0048646 250 0.034
regulation of primary metabolic process GO:0080090 292 0.033
nucleoside triphosphate catabolic process GO:0009143 72 0.033
macromolecule modification GO:0043412 218 0.032
protein phosphorylation GO:0006468 85 0.032
nucleotide metabolic process GO:0009117 108 0.032
defense response GO:0006952 296 0.032
organophosphate metabolic process GO:0019637 125 0.032
epithelial tube morphogenesis GO:0060562 1 0.032
inductive cell migration GO:0040039 145 0.031
regulation of cellular ketone metabolic process GO:0010565 3 0.031
intracellular signal transduction GO:0035556 96 0.031
neurological system process GO:0050877 53 0.030
peptidyl serine modification GO:0018209 20 0.030
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.030
negative regulation of developmental process GO:0051093 227 0.030
response to organic cyclic compound GO:0014070 10 0.030
response to acid chemical GO:0001101 4 0.029
regulation of molecular function GO:0065009 89 0.029
cellular component biogenesis GO:0044085 297 0.029
inorganic ion transmembrane transport GO:0098660 54 0.029
meiotic cell cycle GO:0051321 335 0.029
protein complex assembly GO:0006461 186 0.028
response to abiotic stimulus GO:0009628 152 0.028
regulation of signal transduction GO:0009966 135 0.028
nucleoside triphosphate metabolic process GO:0009141 87 0.028
g protein coupled receptor signaling pathway GO:0007186 46 0.028
pole plasm assembly GO:0007315 2 0.028
reproductive structure development GO:0048608 850 0.028
heterocycle biosynthetic process GO:0018130 187 0.028
carboxylic acid metabolic process GO:0019752 34 0.028
Human
cellular homeostasis GO:0019725 22 0.028
regulation of cytoplasmic transport GO:1903649 3 0.027
regulation of cellular component size GO:0032535 40 0.027
nucleic acid metabolic process GO:0090304 299 0.027
striated muscle myosin thick filament assembly GO:0071688 138 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.027
phagocytosis GO:0006909 115 0.026
neurotransmitter transport GO:0006836 32 0.026
carbohydrate derivative metabolic process GO:1901135 141 0.026
negative regulation of cellular metabolic process GO:0031324 95 0.026
small molecule metabolic process GO:0044281 186 0.026
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.026
purine nucleotide metabolic process GO:0006163 95 0.025
detection of external stimulus GO:0009581 4 0.025
purine containing compound catabolic process GO:0072523 75 0.025
response to oxygen containing compound GO:1901700 44 0.025
phosphorylation GO:0016310 116 0.025
oviposition GO:0018991 364 0.025
Worm
multi organism reproductive behavior GO:0044705 387 0.025
Worm
regulation of cellular metabolic process GO:0031323 305 0.025
regulation of transcription dna templated GO:0006355 164 0.025
negative regulation of macromolecule metabolic process GO:0010605 229 0.025
aromatic compound biosynthetic process GO:0019438 192 0.025
neuron development GO:0048666 199 0.024
organic cyclic compound biosynthetic process GO:1901362 195 0.024
cellular response to nitrogen compound GO:1901699 24 0.024
regulation of multicellular organism growth GO:0040014 373 0.024
myosin filament organization GO:0031033 138 0.024
sleep GO:0030431 4 0.024
positive regulation of developmental process GO:0051094 408 0.024
purine nucleoside metabolic process GO:0042278 92 0.024
regulation of anatomical structure size GO:0090066 46 0.024
protein catabolic process GO:0030163 162 0.024
response to nitrogen compound GO:1901698 25 0.023
cell death GO:0008219 547 0.023
regulation of reproductive process GO:2000241 66 0.023
regulation of protein localization GO:0032880 50 0.023
regulation of rna metabolic process GO:0051252 173 0.023
apoptotic cell clearance GO:0043277 111 0.023
development of primary sexual characteristics GO:0045137 840 0.023
peptidyl amino acid modification GO:0018193 58 0.023
tube morphogenesis GO:0035239 79 0.022
generation of precursor metabolites and energy GO:0006091 18 0.022
Human
purine ribonucleotide metabolic process GO:0009150 95 0.022
neuron projection development GO:0031175 187 0.022
negative regulation of vulval development GO:0040027 206 0.022
organic substance transport GO:0071702 113 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.022
cellular nitrogen compound catabolic process GO:0044270 119 0.022
organonitrogen compound catabolic process GO:1901565 90 0.022
nucleobase containing compound catabolic process GO:0034655 114 0.022
ion transmembrane transport GO:0034220 91 0.022
protein modification process GO:0036211 207 0.022
transcription dna templated GO:0006351 168 0.022
oogenesis GO:0048477 229 0.021
intracellular transport GO:0046907 77 0.021
regulation of protein metabolic process GO:0051246 81 0.021
amine metabolic process GO:0009308 15 0.021
nucleic acid templated transcription GO:0097659 169 0.021
microtubule based process GO:0007017 182 0.021
regulation of synaptic transmission GO:0050804 34 0.021
organic cyclic compound catabolic process GO:1901361 119 0.021
cellular protein complex assembly GO:0043623 178 0.021
cytosolic calcium ion homeostasis GO:0051480 2 0.021
regulation of calcium ion transport GO:0051924 3 0.020
ribonucleoside triphosphate catabolic process GO:0009203 72 0.020
cation transport GO:0006812 78 0.020
nucleoside phosphate catabolic process GO:1901292 77 0.020
regulation of cellular protein metabolic process GO:0032268 75 0.020
organic acid metabolic process GO:0006082 47 0.020
Human
generation of neurons GO:0048699 235 0.019
vulval development GO:0040025 333 0.019
establishment of spindle localization GO:0051293 51 0.019
ras protein signal transduction GO:0007265 31 0.019
rna metabolic process GO:0016070 228 0.019
positive regulation of gene expression GO:0010628 112 0.019
organonitrogen compound biosynthetic process GO:1901566 44 0.019
negative regulation of signaling GO:0023057 61 0.019
digestive system development GO:0055123 122 0.019
positive regulation of molecular function GO:0044093 61 0.019
single organism biosynthetic process GO:0044711 91 0.019
single organism catabolic process GO:0044712 129 0.019
response to biotic stimulus GO:0009607 101 0.019
regulation of macromolecule biosynthetic process GO:0010556 189 0.018
glycosyl compound metabolic process GO:1901657 100 0.018
rna biosynthetic process GO:0032774 169 0.018
membrane invagination GO:0010324 98 0.018
regulation of post embryonic development GO:0048580 260 0.018
regulation of cellular catabolic process GO:0031329 51 0.018
chromosome organization GO:0051276 104 0.018
regulation of biosynthetic process GO:0009889 189 0.018
ribonucleotide metabolic process GO:0009259 99 0.018
regulation of multicellular organismal development GO:2000026 317 0.018
actin filament based movement GO:0030048 4 0.017
cuticle development GO:0042335 100 0.017
purine nucleoside triphosphate catabolic process GO:0009146 72 0.017
regulation of vulval development GO:0040028 248 0.017
regulation of striated muscle contraction GO:0006942 4 0.017
neuron differentiation GO:0030182 217 0.017
cellular ketone metabolic process GO:0042180 14 0.017
cell division GO:0051301 262 0.017
oxidation reduction process GO:0055114 59 0.017
Human
purine ribonucleoside metabolic process GO:0046128 92 0.017
cell type specific apoptotic process GO:0097285 4 0.017
epidermis development GO:0008544 24 0.017
regulation of intracellular signal transduction GO:1902531 77 0.017
regulation of nucleic acid templated transcription GO:1903506 165 0.017
engulfment of apoptotic cell GO:0043652 94 0.017
cellular protein localization GO:0034613 75 0.016
regulation of cellular biosynthetic process GO:0031326 189 0.016
striated muscle contraction GO:0006941 17 0.016
nucleobase containing compound biosynthetic process GO:0034654 184 0.016
membrane organization GO:0061024 135 0.016
multi organism behavior GO:0051705 389 0.016
Worm
nucleobase containing small molecule metabolic process GO:0055086 115 0.016
muscle system process GO:0003012 43 0.016
anion transport GO:0006820 30 0.016
regulation of cell differentiation GO:0045595 81 0.016
sensory organ morphogenesis GO:0090596 2 0.016
neurogenesis GO:0022008 236 0.016
regulation of gene expression epigenetic GO:0040029 163 0.016
single organism behavior GO:0044708 83 0.016
defense response to other organism GO:0098542 100 0.016
response to extracellular stimulus GO:0009991 38 0.016
dauer larval development GO:0040024 92 0.016
gonad development GO:0008406 840 0.015
nucleoside metabolic process GO:0009116 99 0.015
positive regulation of protein transport GO:0051222 4 0.015
response to external biotic stimulus GO:0043207 101 0.015
regulation of cell morphogenesis GO:0022604 40 0.015
cellular response to organonitrogen compound GO:0071417 14 0.015
cellular amino acid metabolic process GO:0006520 15 0.015
carbohydrate derivative catabolic process GO:1901136 82 0.015
regulation of catalytic activity GO:0050790 78 0.015
cellular protein catabolic process GO:0044257 37 0.015
purine nucleotide catabolic process GO:0006195 75 0.015
response to nutrient levels GO:0031667 35 0.015
fertilization GO:0009566 63 0.015
reproductive system development GO:0061458 850 0.014
regulation of nitrogen compound metabolic process GO:0051171 222 0.014
nervous system development GO:0007399 253 0.014
Human
regulation of nucleocytoplasmic transport GO:0046822 3 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
calcium ion transport GO:0006816 16 0.014
aromatic compound catabolic process GO:0019439 116 0.014
apical junction assembly GO:0043297 1 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
eating behavior GO:0042755 59 0.014
gene silencing by rna GO:0031047 143 0.014
cation transmembrane transport GO:0098655 59 0.014
nucleoside catabolic process GO:0009164 78 0.013
ribonucleotide catabolic process GO:0009261 75 0.013
ribonucleoside catabolic process GO:0042454 77 0.013
positive regulation of transport GO:0051050 32 0.013
cellular macromolecular complex assembly GO:0034622 184 0.013
cellular response to stress GO:0033554 162 0.013
posttranscriptional gene silencing by rna GO:0035194 143 0.013
metal ion transport GO:0030001 49 0.013
cellular macromolecule localization GO:0070727 75 0.013
gene silencing GO:0016458 143 0.013
establishment of mitotic spindle localization GO:0040001 41 0.013
chromatin remodeling GO:0006338 2 0.013
oxoacid metabolic process GO:0043436 47 0.013
Human
transmembrane transport GO:0055085 110 0.013
negative regulation of gene expression GO:0010629 217 0.012
tube development GO:0035295 126 0.012
determination of left right symmetry GO:0007368 9 0.012
oocyte differentiation GO:0009994 45 0.012
regulation of cell development GO:0060284 49 0.012
spindle localization GO:0051653 51 0.012
defense response to gram negative bacterium GO:0050829 64 0.012
innate immune response GO:0045087 190 0.012
post embryonic organ development GO:0048569 336 0.012
negative regulation of cellular biosynthetic process GO:0031327 65 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.012
regulation of response to wounding GO:1903034 1 0.012
neuromuscular junction development GO:0007528 2 0.012
regulation of system process GO:0044057 27 0.012
response to inorganic substance GO:0010035 50 0.012
axon development GO:0061564 163 0.012
hormone metabolic process GO:0042445 3 0.012
establishment of mitotic spindle orientation GO:0000132 28 0.012
single organism membrane organization GO:0044802 35 0.012
meiotic nuclear division GO:0007126 300 0.012
regulation of cell cycle process GO:0010564 145 0.012
regulation of cell size GO:0008361 30 0.012
cytoplasmic transport GO:0016482 23 0.012
cell morphogenesis GO:0000902 163 0.012
regulation of lipid metabolic process GO:0019216 4 0.012
ribonucleoside triphosphate metabolic process GO:0009199 87 0.011
cellular component assembly GO:0022607 293 0.011
small gtpase mediated signal transduction GO:0007264 32 0.011
regulation of phosphorylation GO:0042325 45 0.011
negative regulation of cellular component organization GO:0051129 33 0.011
purine nucleoside triphosphate metabolic process GO:0009144 87 0.011
positive regulation of metabolic process GO:0009893 187 0.011
negative regulation of signal transduction GO:0009968 60 0.011
ion homeostasis GO:0050801 21 0.011
nucleotide catabolic process GO:0009166 77 0.011
regulation of organelle organization GO:0033043 164 0.011
cytokinesis GO:0000910 80 0.011
cell cycle GO:0007049 526 0.011
muscle fiber development GO:0048747 2 0.011
cellular response to unfolded protein GO:0034620 71 0.011
positive regulation of cellular metabolic process GO:0031325 178 0.011
regulation of multi organism process GO:0043900 69 0.011
response to other organism GO:0051707 101 0.011
carboxylic acid catabolic process GO:0046395 3 0.011
positive regulation of biosynthetic process GO:0009891 109 0.011
detection of abiotic stimulus GO:0009582 4 0.011
ribose phosphate metabolic process GO:0019693 99 0.011
regulation of protein targeting GO:1903533 3 0.011
collagen and cuticulin based cuticle development GO:0040002 99 0.011
phagocytosis engulfment GO:0006911 98 0.011
negative regulation of cell communication GO:0010648 61 0.010
regulation of lipid transport GO:0032368 4 0.010
posttranscriptional gene silencing GO:0016441 143 0.010
developmental maturation GO:0021700 26 0.010
transcription from rna polymerase ii promoter GO:0006366 149 0.010
regulation of cell cycle GO:0051726 194 0.010
cellular macromolecule catabolic process GO:0044265 73 0.010
divalent inorganic cation transport GO:0072511 17 0.010

sdha-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.014
Human
disease of cellular proliferation DOID:14566 0 0.014
Human
organ system cancer DOID:0050686 0 0.014
Human
disease of anatomical entity DOID:7 0 0.012
Human
nervous system disease DOID:863 0 0.011