Caenorhabditis elegans

21 known processes

his-42 (CELE_F08G2.3)

Protein HIS-42

his-42 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
digestive tract development GO:0048565 122 0.983
pharynx development GO:0060465 51 0.977
meiotic cell cycle process GO:1903046 170 0.961
meiotic cell cycle GO:0051321 335 0.940
reproductive system development GO:0061458 850 0.933
Worm
reproductive structure development GO:0048608 850 0.923
Worm
digestive system development GO:0055123 122 0.906
genitalia development GO:0048806 741 0.896
Worm
hermaphrodite genitalia development GO:0040035 734 0.892
Worm
embryo development ending in birth or egg hatching GO:0009792 2992 0.873
development of primary sexual characteristics GO:0045137 840 0.860
Worm
sexual reproduction GO:0019953 546 0.817
gonad development GO:0008406 840 0.814
Worm
organ development GO:0048513 1102 0.804
Worm
sex differentiation GO:0007548 909 0.800
Worm
embryo development GO:0009790 3052 0.790
multicellular organism reproduction GO:0032504 819 0.783
tube development GO:0035295 126 0.761
post embryonic development GO:0009791 2152 0.746
single organism reproductive process GO:0044702 1196 0.696
Worm
developmental process involved in reproduction GO:0003006 1165 0.653
Worm
multicellular organismal reproductive behavior GO:0033057 384 0.604
defense response GO:0006952 296 0.592
multicellular organismal reproductive process GO:0048609 815 0.590
locomotion GO:0040011 1634 0.573
Worm
organelle organization GO:0006996 783 0.546
multi organism reproductive process GO:0044703 867 0.490
dna repair GO:0006281 23 0.484
negative regulation of gene expression epigenetic GO:0045814 2 0.473
oviposition GO:0018991 364 0.453
dna metabolic process GO:0006259 74 0.420
gene expression GO:0010467 412 0.416
negative regulation of cellular process GO:0048523 239 0.412
rna biosynthetic process GO:0032774 169 0.397
single organism organelle organization GO:1902589 501 0.377
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.368
macromolecule biosynthetic process GO:0009059 250 0.361
transcription dna templated GO:0006351 168 0.354
cell cycle process GO:0022402 482 0.353
nucleobase containing compound metabolic process GO:0006139 406 0.351
innate immune response GO:0045087 190 0.349
cell cycle GO:0007049 526 0.336
mitotic sister chromatid segregation GO:0000070 38 0.323
nucleic acid metabolic process GO:0090304 299 0.323
nucleic acid templated transcription GO:0097659 169 0.319
heterocycle biosynthetic process GO:0018130 187 0.318
chromosome organization GO:0051276 104 0.306
nucleobase containing compound biosynthetic process GO:0034654 184 0.297
regulation of macromolecule metabolic process GO:0060255 421 0.296
cellular response to dna damage stimulus GO:0006974 41 0.269
rna metabolic process GO:0016070 228 0.265
cellular nitrogen compound biosynthetic process GO:0044271 192 0.260
negative regulation of metabolic process GO:0009892 240 0.257
cellular macromolecule biosynthetic process GO:0034645 247 0.249
negative regulation of macromolecule metabolic process GO:0010605 229 0.230
gene silencing GO:0016458 143 0.228
aromatic compound biosynthetic process GO:0019438 192 0.222
mitotic nuclear division GO:0007067 89 0.216
cellular biosynthetic process GO:0044249 315 0.215
regulation of gene expression GO:0010468 366 0.214
negative regulation of biosynthetic process GO:0009890 65 0.200
negative regulation of gene expression GO:0010629 217 0.199
organic cyclic compound biosynthetic process GO:1901362 195 0.198
aging GO:0007568 812 0.197
Worm
meiotic nuclear division GO:0007126 300 0.197
negative regulation of biological process GO:0048519 567 0.194
multi organism reproductive behavior GO:0044705 387 0.193
negative regulation of nucleic acid templated transcription GO:1903507 53 0.186
anatomical structure formation involved in morphogenesis GO:0048646 250 0.186
body morphogenesis GO:0010171 620 0.179
regulation of rna metabolic process GO:0051252 173 0.173
cellular protein metabolic process GO:0044267 279 0.173
biosynthetic process GO:0009058 323 0.172
negative regulation of transcription dna templated GO:0045892 53 0.172
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.169
determination of adult lifespan GO:0008340 812 0.167
Worm
regulation of metabolic process GO:0019222 478 0.166
regulation of cellular metabolic process GO:0031323 305 0.165
cellular response to stress GO:0033554 162 0.165
organic substance biosynthetic process GO:1901576 323 0.164
meiotic chromosome segregation GO:0045132 139 0.162
fertilization GO:0009566 63 0.144
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.144
macromolecular complex subunit organization GO:0043933 320 0.142
single organism transport GO:0044765 447 0.141
histone modification GO:0016570 30 0.137
regulation of primary metabolic process GO:0080090 292 0.136
negative regulation of cellular metabolic process GO:0031324 95 0.135
cellular component biogenesis GO:0044085 297 0.134
multi multicellular organism process GO:0044706 390 0.133
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.131
establishment of localization GO:0051234 1171 0.129
transport GO:0006810 1093 0.126
regulation of organelle organization GO:0033043 164 0.124
gamete generation GO:0007276 461 0.124
negative regulation of cellular catabolic process GO:0031330 9 0.123
regulation of cellular component organization GO:0051128 248 0.122
multicellular organismal aging GO:0010259 812 0.120
Worm
cell division GO:0051301 262 0.117
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.117
cellular component assembly GO:0022607 293 0.116
macromolecule localization GO:0033036 771 0.114
multi organism behavior GO:0051705 389 0.113
programmed cell death GO:0012501 500 0.109
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.103
cellular component assembly involved in morphogenesis GO:0010927 183 0.102
regulation of chromosome organization GO:0033044 20 0.098
organelle fission GO:0048285 363 0.098
regulation of macromolecule biosynthetic process GO:0010556 189 0.098
endocytosis GO:0006897 819 0.097
regulation of rna biosynthetic process GO:2001141 165 0.097
organelle assembly GO:0070925 214 0.093
protein complex subunit organization GO:0071822 280 0.093
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.091
protein metabolic process GO:0019538 422 0.090
regulation of nucleic acid templated transcription GO:1903506 165 0.090
cellular protein modification process GO:0006464 207 0.089
reproductive behavior GO:0019098 387 0.088
cellular component morphogenesis GO:0032989 318 0.088
macromolecule catabolic process GO:0009057 202 0.088
regulation of transcription dna templated GO:0006355 164 0.086
germ cell development GO:0007281 351 0.086
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.086
nucleus organization GO:0006997 38 0.082
modification dependent macromolecule catabolic process GO:0043632 32 0.082
sister chromatid segregation GO:0000819 46 0.082
negative regulation of cell cycle GO:0045786 53 0.081
mitotic cell cycle process GO:1903047 194 0.081
cellular localization GO:0051641 360 0.081
regulation of biological quality GO:0065008 741 0.081
regulation of cell cycle process GO:0010564 145 0.081
regulation of cell division GO:0051302 142 0.081
single organism localization GO:1902578 518 0.080
maintenance of location GO:0051235 580 0.080
regulation of nitrogen compound metabolic process GO:0051171 222 0.079
negative regulation of cellular biosynthetic process GO:0031327 65 0.079
actomyosin structure organization GO:0031032 154 0.078
receptor mediated endocytosis GO:0006898 715 0.078
cytoskeleton organization GO:0007010 339 0.076
regulation of cellular biosynthetic process GO:0031326 189 0.076
vesicle mediated transport GO:0016192 852 0.076
regulation of cell cycle GO:0051726 194 0.075
negative regulation of rna biosynthetic process GO:1902679 53 0.073
pronuclear migration GO:0035046 51 0.072
regulation of gene expression epigenetic GO:0040029 163 0.071
apoptotic process GO:0006915 478 0.071
chromatin assembly or disassembly GO:0006333 1 0.069
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 5 0.069
lipid storage GO:0019915 565 0.066
mitotic sister chromatid separation GO:0051306 13 0.065
single organism catabolic process GO:0044712 129 0.065
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.064
spindle checkpoint GO:0031577 4 0.063
lipid localization GO:0010876 573 0.062
establishment of localization in cell GO:0051649 318 0.058
cell death GO:0008219 547 0.058
behavior GO:0007610 527 0.058
positive regulation of cellular process GO:0048522 332 0.056
regulation of cellular catabolic process GO:0031329 51 0.056
regulation of sister chromatid segregation GO:0033045 16 0.056
negative regulation of nuclear division GO:0051784 6 0.055
myofibril assembly GO:0030239 154 0.053
metaphase anaphase transition of mitotic cell cycle GO:0007091 10 0.053
proteolysis GO:0006508 61 0.053
muscle structure development GO:0061061 191 0.052
secretion GO:0046903 147 0.052
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.051
female gamete generation GO:0007292 254 0.051
regulation of protein metabolic process GO:0051246 81 0.051
cell development GO:0048468 696 0.051
metaphase anaphase transition of cell cycle GO:0044784 15 0.050
oogenesis GO:0048477 229 0.050
proteasomal protein catabolic process GO:0010498 20 0.049
catabolic process GO:0009056 318 0.049
macromolecule modification GO:0043412 218 0.049
modification dependent protein catabolic process GO:0019941 32 0.047
striated muscle cell development GO:0055002 157 0.045
cellular catabolic process GO:0044248 199 0.045
oocyte axis specification GO:0007309 2 0.045
muscle cell differentiation GO:0042692 171 0.044
death GO:0016265 547 0.043
regulation of cellular protein metabolic process GO:0032268 75 0.043
negative regulation of mitotic metaphase anaphase transition GO:0045841 4 0.043
secretion by cell GO:0032940 138 0.042
positive regulation of macromolecule metabolic process GO:0010604 149 0.040
regulation of mitotic sister chromatid segregation GO:0033047 16 0.039
ubiquitin dependent protein catabolic process GO:0006511 32 0.039
single fertilization GO:0007338 61 0.037
negative regulation of organelle organization GO:0010639 20 0.037
regulation of meiotic cell cycle GO:0051445 136 0.037
protein modification process GO:0036211 207 0.037
myosin filament assembly GO:0031034 138 0.037
muscle cell development GO:0055001 158 0.037
negative regulation of catabolic process GO:0009895 9 0.036
organic substance catabolic process GO:1901575 294 0.035
positive regulation of metabolic process GO:0009893 187 0.035
regulation of catabolic process GO:0009894 57 0.035
chromatin organization GO:0006325 32 0.035
cellular protein catabolic process GO:0044257 37 0.034
chromosome segregation GO:0007059 180 0.034
regulation of mitotic cell cycle GO:0007346 76 0.034
regulation of biosynthetic process GO:0009889 189 0.034
transcription from rna polymerase ii promoter GO:0006366 149 0.033
covalent chromatin modification GO:0016569 30 0.033
regulation of protein catabolic process GO:0042176 13 0.033
cellular macromolecular complex assembly GO:0034622 184 0.033
protein complex assembly GO:0006461 186 0.033
vulval development GO:0040025 333 0.033
negative regulation of rna metabolic process GO:0051253 53 0.032
macromolecular complex assembly GO:0065003 193 0.032
striated muscle myosin thick filament assembly GO:0071688 138 0.032
cellular protein complex assembly GO:0043623 178 0.032
protein complex biogenesis GO:0070271 186 0.031
cell cycle phase transition GO:0044770 19 0.031
striated muscle cell differentiation GO:0051146 158 0.030
chromatin modification GO:0016568 32 0.030
negative regulation of chromosome segregation GO:0051985 4 0.029
immune response GO:0006955 192 0.029
actin filament based process GO:0030029 191 0.028
regulation of nuclear division GO:0051783 115 0.028
cellular macromolecule catabolic process GO:0044265 73 0.026
actin cytoskeleton organization GO:0030036 184 0.026
response to wounding GO:0009611 4 0.026
myosin filament organization GO:0031033 138 0.026
negative regulation of mitotic sister chromatid segregation GO:0033048 4 0.025
mitotic cell cycle phase transition GO:0044772 13 0.024
negative regulation of protein metabolic process GO:0051248 27 0.024
regulation of vulval development GO:0040028 248 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 20 0.023
negative regulation of cellular component organization GO:0051129 33 0.023
positive regulation of developmental growth GO:0048639 354 0.022
negative regulation of nematode larval development GO:0061064 208 0.021
synaptic growth at neuromuscular junction GO:0051124 1 0.021
regulation of developmental growth GO:0048638 389 0.019
oocyte differentiation GO:0009994 45 0.019
negative regulation of cellular protein metabolic process GO:0032269 27 0.019
negative regulation of cellular protein catabolic process GO:1903363 4 0.019
regulation of apoptotic signaling pathway GO:2001233 1 0.018
positive regulation of multicellular organism growth GO:0040018 352 0.018
positive regulation of cellular biosynthetic process GO:0031328 109 0.018
posttranscriptional gene silencing GO:0016441 143 0.018
oocyte construction GO:0007308 2 0.017
growth GO:0040007 562 0.017
organelle localization GO:0051640 127 0.017
regulation of multicellular organism growth GO:0040014 373 0.017
molting cycle GO:0042303 281 0.016
posttranscriptional regulation of gene expression GO:0010608 166 0.016
oocyte development GO:0048599 44 0.015
nucleotide excision repair GO:0006289 6 0.015
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 4 0.015
mitotic cell cycle checkpoint GO:0007093 5 0.015
ribosome biogenesis GO:0042254 4 0.015
regulation of growth GO:0040008 409 0.015
multicellular organism growth GO:0035264 385 0.015
regulation of mitotic metaphase anaphase transition GO:0030071 5 0.015
positive regulation of developmental process GO:0051094 408 0.015
sensory organ morphogenesis GO:0090596 2 0.015
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 4 0.015
regulation of chromosome segregation GO:0051983 20 0.014
rna interference GO:0016246 137 0.014
regulation of developmental process GO:0050793 684 0.014
negative regulation of multicellular organismal process GO:0051241 236 0.014
positive regulation of cellular metabolic process GO:0031325 178 0.014
negative regulation of cell cycle phase transition GO:1901988 6 0.014
single organism signaling GO:0044700 401 0.014
positive regulation of growth GO:0045927 369 0.014
negative regulation of proteasomal protein catabolic process GO:1901799 4 0.014
posttranscriptional gene silencing by rna GO:0035194 143 0.014
negative regulation of mitosis GO:0045839 4 0.014
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 10 0.013
protein oligomerization GO:0051259 4 0.013
regulation of multicellular organismal process GO:0051239 726 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.013
negative regulation of developmental process GO:0051093 227 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 5 0.013
regulation of meiosis GO:0040020 94 0.013
developmental growth GO:0048589 412 0.013
positive regulation of gene expression GO:0010628 112 0.013
chromosome separation GO:0051304 19 0.013
neuromuscular junction development GO:0007528 2 0.013
defense response to bacterium GO:0042742 86 0.012
nervous system development GO:0007399 253 0.012
inductive cell migration GO:0040039 145 0.012
regulation of synapse assembly GO:0051963 2 0.012
negative regulation of protein catabolic process GO:0042177 4 0.012
cell type specific apoptotic process GO:0097285 4 0.011
defense response to gram negative bacterium GO:0050829 64 0.011
signaling GO:0023052 401 0.011
regulation of nematode larval development GO:0061062 260 0.011
positive regulation of transcription dna templated GO:0045893 102 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 5 0.011
microtubule based process GO:0007017 182 0.011
pole plasm assembly GO:0007315 2 0.011
small molecule metabolic process GO:0044281 186 0.011
negative regulation of post embryonic development GO:0048581 208 0.010

his-42 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021