Caenorhabditis elegans

44 known processes

klc-1 (CELE_M7.2)

Protein KLC-1

klc-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic cell cycle GO:0051321 335 0.905
meiotic cell cycle process GO:1903046 170 0.709
meiotic chromosome segregation GO:0045132 139 0.689
embryo development ending in birth or egg hatching GO:0009792 2992 0.644
post embryonic development GO:0009791 2152 0.641
Worm
transport GO:0006810 1093 0.591
Worm
locomotion GO:0040011 1634 0.587
Worm
embryo development GO:0009790 3052 0.580
meiotic nuclear division GO:0007126 300 0.563
developmental process involved in reproduction GO:0003006 1165 0.532
single organism reproductive process GO:0044702 1196 0.504
single organism organelle organization GO:1902589 501 0.424
organelle organization GO:0006996 783 0.317
protein complex subunit organization GO:0071822 280 0.296
apoptotic process GO:0006915 478 0.295
cell cycle GO:0007049 526 0.292
chromosome segregation GO:0007059 180 0.288
endocytosis GO:0006897 819 0.270
vesicle mediated transport GO:0016192 852 0.263
Worm
cell cycle process GO:0022402 482 0.223
regulation of cell cycle GO:0051726 194 0.220
sexual reproduction GO:0019953 546 0.206
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.204
body morphogenesis GO:0010171 620 0.201
receptor mediated endocytosis GO:0006898 715 0.185
multicellular organism reproduction GO:0032504 819 0.176
gamete generation GO:0007276 461 0.162
germ cell development GO:0007281 351 0.157
growth GO:0040007 562 0.147
Worm
multicellular organismal reproductive process GO:0048609 815 0.144
establishment of localization GO:0051234 1171 0.141
cell development GO:0048468 696 0.132
Worm
macromolecular complex subunit organization GO:0043933 320 0.113
development of primary sexual characteristics GO:0045137 840 0.111
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.108
regulation of developmental process GO:0050793 684 0.105
signal transduction GO:0007165 317 0.098
organelle fission GO:0048285 363 0.097
genitalia development GO:0048806 741 0.097
death GO:0016265 547 0.094
reproductive system development GO:0061458 850 0.093
programmed cell death GO:0012501 500 0.090
cellular localization GO:0051641 360 0.089
cytoskeleton organization GO:0007010 339 0.089
single organism signaling GO:0044700 401 0.088
Worm
cell death GO:0008219 547 0.084
multicellular organismal reproductive behavior GO:0033057 384 0.082
cell division GO:0051301 262 0.082
molting cycle GO:0042303 281 0.080
behavior GO:0007610 527 0.079
multicellular organism growth GO:0035264 385 0.079
multi organism reproductive process GO:0044703 867 0.077
regulation of growth GO:0040008 409 0.077
reproductive behavior GO:0019098 387 0.073
oviposition GO:0018991 364 0.073
signaling GO:0023052 401 0.073
Worm
hermaphrodite genitalia development GO:0040035 734 0.073
organ development GO:0048513 1102 0.067
endomembrane system organization GO:0010256 22 0.067
positive regulation of macromolecule metabolic process GO:0010604 149 0.066
sex differentiation GO:0007548 909 0.064
head development GO:0060322 1 0.064
single organism localization GO:1902578 518 0.063
cell cell signaling GO:0007267 118 0.063
Worm
reproductive structure development GO:0048608 850 0.063
regulation of biological quality GO:0065008 741 0.060
positive regulation of cellular metabolic process GO:0031325 178 0.060
maintenance of location GO:0051235 580 0.060
cellular component morphogenesis GO:0032989 318 0.060
Worm
positive regulation of multicellular organismal process GO:0051240 417 0.058
multi organism behavior GO:0051705 389 0.058
lipid storage GO:0019915 565 0.056
positive regulation of cellular process GO:0048522 332 0.055
cellular component biogenesis GO:0044085 297 0.055
phosphorus metabolic process GO:0006793 232 0.055
nucleobase containing compound metabolic process GO:0006139 406 0.054
chromosome organization GO:0051276 104 0.052
lipid localization GO:0010876 573 0.052
macromolecule localization GO:0033036 771 0.051
gonad development GO:0008406 840 0.051
developmental growth GO:0048589 412 0.050
Worm
protein complex assembly GO:0006461 186 0.050
phosphate containing compound metabolic process GO:0006796 232 0.050
regulation of developmental growth GO:0048638 389 0.048
regulation of primary metabolic process GO:0080090 292 0.048
cellular protein modification process GO:0006464 207 0.047
cellular macromolecule localization GO:0070727 75 0.047
macromolecule modification GO:0043412 218 0.046
oogenesis GO:0048477 229 0.045
striated muscle cell differentiation GO:0051146 158 0.042
multi organism reproductive behavior GO:0044705 387 0.041
cellular response to stress GO:0033554 162 0.040
determination of adult lifespan GO:0008340 812 0.039
regulation of multicellular organism growth GO:0040014 373 0.039
regulation of organelle organization GO:0033043 164 0.038
actin filament based process GO:0030029 191 0.037
response to abiotic stimulus GO:0009628 152 0.037
anatomical structure formation involved in morphogenesis GO:0048646 250 0.036
regulation of cellular component organization GO:0051128 248 0.036
protein metabolic process GO:0019538 422 0.036
multi multicellular organism process GO:0044706 390 0.035
protein phosphorylation GO:0006468 85 0.035
positive regulation of multicellular organism growth GO:0040018 352 0.035
synaptic transmission GO:0007268 106 0.035
Worm
regulation of epithelial cell proliferation GO:0050678 1 0.034
actin cytoskeleton organization GO:0030036 184 0.034
cellular component assembly GO:0022607 293 0.034
cellular macromolecular complex assembly GO:0034622 184 0.033
macromolecular complex assembly GO:0065003 193 0.033
positive regulation of growth GO:0045927 369 0.032
positive regulation of developmental growth GO:0048639 354 0.032
aging GO:0007568 812 0.031
muscle cell differentiation GO:0042692 171 0.031
nucleic acid metabolic process GO:0090304 299 0.031
cellular component assembly involved in morphogenesis GO:0010927 183 0.031
catabolic process GO:0009056 318 0.030
cellular component movement GO:0006928 388 0.030
positive regulation of metabolic process GO:0009893 187 0.030
striated muscle cell development GO:0055002 157 0.029
macromolecule catabolic process GO:0009057 202 0.029
regulation of cell cycle process GO:0010564 145 0.029
regulation of multicellular organismal process GO:0051239 726 0.029
protein complex biogenesis GO:0070271 186 0.029
phosphorylation GO:0016310 116 0.028
pronuclear migration GO:0035046 51 0.028
regulation of chromosome organization GO:0033044 20 0.027
cell motility GO:0048870 313 0.027
regulation of response to stimulus GO:0048583 243 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.026
multicellular organismal aging GO:0010259 812 0.026
cell migration GO:0016477 306 0.026
localization of cell GO:0051674 313 0.026
cellular protein localization GO:0034613 75 0.025
single organism transport GO:0044765 447 0.024
Worm
inductive cell migration GO:0040039 145 0.024
regulation of cytoplasmic transport GO:1903649 3 0.024
establishment of localization in cell GO:0051649 318 0.024
regulation of cell division GO:0051302 142 0.024
regulation of metabolic process GO:0019222 478 0.023
muscle cell development GO:0055001 158 0.023
microtubule based process GO:0007017 182 0.023
regulation of cell communication GO:0010646 176 0.022
cellular protein complex assembly GO:0043623 178 0.022
dna metabolic process GO:0006259 74 0.021
single organism behavior GO:0044708 83 0.021
intracellular signal transduction GO:0035556 96 0.021
synaptic vesicle transport GO:0048489 21 0.021
Worm
myosin filament organization GO:0031033 138 0.020
hermaphrodite germ line sex determination GO:0040021 48 0.020
regulation of phosphate metabolic process GO:0019220 81 0.020
myofibril assembly GO:0030239 154 0.020
regulation of programmed cell death GO:0043067 50 0.020
mitotic cell cycle process GO:1903047 194 0.020
cell surface receptor signaling pathway GO:0007166 149 0.019
dna recombination GO:0006310 19 0.019
positive regulation of developmental process GO:0051094 408 0.019
immune response GO:0006955 192 0.018
single fertilization GO:0007338 61 0.018
response to oxygen containing compound GO:1901700 44 0.018
actomyosin structure organization GO:0031032 154 0.018
positive regulation of cell death GO:0010942 38 0.018
sex determination GO:0007530 60 0.018
positive regulation of chromosome segregation GO:0051984 1 0.018
regulation of signal transduction GO:0009966 135 0.017
organic substance catabolic process GO:1901575 294 0.017
regulation of cell death GO:0010941 65 0.017
myosin filament assembly GO:0031034 138 0.017
regulation of cell proliferation GO:0042127 105 0.017
positive regulation of cellular component organization GO:0051130 34 0.016
canonical wnt signaling pathway GO:0060070 3 0.016
protein modification process GO:0036211 207 0.016
striated muscle myosin thick filament assembly GO:0071688 138 0.016
germ line sex determination GO:0018992 51 0.016
cellular response to endogenous stimulus GO:0071495 32 0.016
muscle structure development GO:0061061 191 0.016
regulation of meiotic cell cycle GO:0051445 136 0.016
protein localization GO:0008104 205 0.015
regulation of cellular metabolic process GO:0031323 305 0.015
double strand break repair GO:0006302 5 0.015
regulation of macromolecule metabolic process GO:0060255 421 0.015
establishment of nucleus localization GO:0040023 55 0.015
organelle localization GO:0051640 127 0.014
negative regulation of cellular process GO:0048523 239 0.014
gene silencing by rna GO:0031047 143 0.014
female gamete generation GO:0007292 254 0.014
regulation of mesoderm development GO:2000380 2 0.014
aromatic compound biosynthetic process GO:0019438 192 0.014
regulation of gene expression GO:0010468 366 0.013
nucleic acid templated transcription GO:0097659 169 0.013
organelle assembly GO:0070925 214 0.013
cellular macromolecule catabolic process GO:0044265 73 0.013
generation of neurons GO:0048699 235 0.013
Worm
cell type specific apoptotic process GO:0097285 4 0.013
cellular protein metabolic process GO:0044267 279 0.013
neuromuscular junction development GO:0007528 2 0.013
rna metabolic process GO:0016070 228 0.013
membrane organization GO:0061024 135 0.013
cellular macromolecule biosynthetic process GO:0034645 247 0.013
cellular response to abiotic stimulus GO:0071214 4 0.013
chromosome organization involved in meiosis GO:0070192 25 0.013
positive regulation of cellular protein catabolic process GO:1903364 3 0.013
organic substance transport GO:0071702 113 0.012
negative regulation of biological process GO:0048519 567 0.012
protein oligomerization GO:0051259 4 0.012
nervous system development GO:0007399 253 0.012
Worm
positive regulation of epithelial cell proliferation GO:0050679 1 0.012
cytoskeleton dependent cytokinesis GO:0061640 35 0.012
positive regulation of proteasomal protein catabolic process GO:1901800 1 0.012
cellular biosynthetic process GO:0044249 315 0.012
regulation of molecular function GO:0065009 89 0.012
response to external stimulus GO:0009605 289 0.012
regulation of anatomical structure morphogenesis GO:0022603 51 0.012
regulation of signaling GO:0023051 172 0.012
amine metabolic process GO:0009308 15 0.011
cellular catabolic process GO:0044248 199 0.011
regulation of rna biosynthetic process GO:2001141 165 0.011
regulation of protein targeting GO:1903533 3 0.011
positive regulation of mitotic sister chromatid separation GO:1901970 1 0.011
cell proliferation GO:0008283 116 0.011
heterocycle biosynthetic process GO:0018130 187 0.011
single organism membrane organization GO:0044802 35 0.011
homeostatic process GO:0042592 51 0.011
biosynthetic process GO:0009058 323 0.011
vesicle localization GO:0051648 24 0.011
Worm
innate immune response GO:0045087 190 0.011
cellular response to chemical stimulus GO:0070887 129 0.010
regulation of nucleocytoplasmic transport GO:0046822 3 0.010
negative regulation of multicellular organismal process GO:0051241 236 0.010
secretion by cell GO:0032940 138 0.010
negative regulation of cell cycle GO:0045786 53 0.010

klc-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.029
cancer DOID:162 0 0.022
organ system cancer DOID:0050686 0 0.022