Caenorhabditis elegans

84 known processes

let-70 (CELE_M7.1)

Protein LET-70

let-70 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.817
post embryonic development GO:0009791 2152 0.805
sexual reproduction GO:0019953 546 0.720
locomotion GO:0040011 1634 0.649
multicellular organism reproduction GO:0032504 819 0.593
developmental process involved in reproduction GO:0003006 1165 0.572
organ development GO:0048513 1102 0.542
gonad development GO:0008406 840 0.534
germ cell development GO:0007281 351 0.533
programmed cell death GO:0012501 500 0.481
single organism reproductive process GO:0044702 1196 0.460
establishment of localization GO:0051234 1171 0.453
Worm
sex differentiation GO:0007548 909 0.400
death GO:0016265 547 0.392
cell death GO:0008219 547 0.383
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.357
cell migration GO:0016477 306 0.356
gamete generation GO:0007276 461 0.355
regulation of multicellular organismal process GO:0051239 726 0.349
Fly
apoptotic process GO:0006915 478 0.344
development of primary sexual characteristics GO:0045137 840 0.328
cellular component movement GO:0006928 388 0.326
multicellular organismal reproductive process GO:0048609 815 0.309
regulation of developmental process GO:0050793 684 0.304
Fly
cell cycle GO:0007049 526 0.300
negative regulation of vulval development GO:0040027 206 0.297
regulation of macromolecule metabolic process GO:0060255 421 0.291
Fly
vulval development GO:0040025 333 0.291
embryo development GO:0009790 3052 0.285
regulation of multicellular organismal development GO:2000026 317 0.278
Fly
regulation of vulval development GO:0040028 248 0.261
meiotic cell cycle GO:0051321 335 0.253
regulation of nematode larval development GO:0061062 260 0.251
hermaphrodite genitalia development GO:0040035 734 0.247
regulation of post embryonic development GO:0048580 260 0.246
receptor mediated endocytosis GO:0006898 715 0.244
Worm
regulation of primary metabolic process GO:0080090 292 0.238
post embryonic organ development GO:0048569 336 0.235
regulation of signaling GO:0023051 172 0.224
reproductive system development GO:0061458 850 0.224
regulation of cell differentiation GO:0045595 81 0.224
Fly
protein modification process GO:0036211 207 0.223
negative regulation of nematode larval development GO:0061064 208 0.216
multicellular organismal aging GO:0010259 812 0.214
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.213
positive regulation of multicellular organismal process GO:0051240 417 0.211
growth GO:0040007 562 0.206
determination of adult lifespan GO:0008340 812 0.201
meiotic nuclear division GO:0007126 300 0.200
rna metabolic process GO:0016070 228 0.187
response to chemical GO:0042221 356 0.183
chromosome organization GO:0051276 104 0.176
Fly
cellular protein modification process GO:0006464 207 0.173
positive regulation of metabolic process GO:0009893 187 0.171
phosphate containing compound metabolic process GO:0006796 232 0.165
female gamete generation GO:0007292 254 0.161
Fly
transport GO:0006810 1093 0.160
Worm
nervous system development GO:0007399 253 0.158
Fly
mitotic cell cycle process GO:1903047 194 0.150
Fly
positive regulation of developmental process GO:0051094 408 0.143
positive regulation of cellular process GO:0048522 332 0.140
cell motility GO:0048870 313 0.139
organelle fission GO:0048285 363 0.139
multicellular organism growth GO:0035264 385 0.139
cellular protein metabolic process GO:0044267 279 0.132
oviposition GO:0018991 364 0.131
regulation of cellular metabolic process GO:0031323 305 0.131
multi organism reproductive process GO:0044703 867 0.129
meiotic cell cycle process GO:1903046 170 0.126
developmental growth GO:0048589 412 0.125
phosphorus metabolic process GO:0006793 232 0.124
regulation of growth GO:0040008 409 0.120
cellular response to chemical stimulus GO:0070887 129 0.119
reproductive structure development GO:0048608 850 0.113
genitalia development GO:0048806 741 0.112
organelle organization GO:0006996 783 0.111
aromatic compound biosynthetic process GO:0019438 192 0.109
aging GO:0007568 812 0.109
cell morphogenesis GO:0000902 163 0.106
negative regulation of multicellular organismal process GO:0051241 236 0.106
positive regulation of growth GO:0045927 369 0.100
regulation of signal transduction GO:0009966 135 0.100
organic substance biosynthetic process GO:1901576 323 0.097
regulation of cell communication GO:0010646 176 0.095
heterocycle biosynthetic process GO:0018130 187 0.095
macromolecule localization GO:0033036 771 0.094
Worm
regulation of biological quality GO:0065008 741 0.094
Worm Fly
negative regulation of biological process GO:0048519 567 0.093
Fly
regulation of rna metabolic process GO:0051252 173 0.092
behavior GO:0007610 527 0.092
signal transduction GO:0007165 317 0.091
regulation of gene expression GO:0010468 366 0.089
Fly
endocytosis GO:0006897 819 0.087
Worm
regulation of nitrogen compound metabolic process GO:0051171 222 0.086
single organism signaling GO:0044700 401 0.086
cellular component morphogenesis GO:0032989 318 0.085
nucleic acid templated transcription GO:0097659 169 0.085
protein metabolic process GO:0019538 422 0.084
tissue development GO:0009888 112 0.084
negative regulation of post embryonic development GO:0048581 208 0.084
regulation of response to stimulus GO:0048583 243 0.084
multicellular organismal reproductive behavior GO:0033057 384 0.083
negative regulation of developmental process GO:0051093 227 0.083
Fly
regulation of biosynthetic process GO:0009889 189 0.083
glycosyl compound metabolic process GO:1901657 100 0.082
nucleic acid metabolic process GO:0090304 299 0.081
generation of neurons GO:0048699 235 0.080
Fly
regulation of multicellular organism growth GO:0040014 373 0.078
rna biosynthetic process GO:0032774 169 0.078
response to wounding GO:0009611 4 0.077
cellular localization GO:0051641 360 0.076
macromolecule biosynthetic process GO:0009059 250 0.076
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.075
maintenance of location GO:0051235 580 0.075
Worm
single organism organelle organization GO:1902589 501 0.073
Fly
regulation of metabolic process GO:0019222 478 0.072
Fly
positive regulation of developmental growth GO:0048639 354 0.072
nucleobase containing compound biosynthetic process GO:0034654 184 0.071
response to external stimulus GO:0009605 289 0.071
negative regulation of macromolecule metabolic process GO:0010605 229 0.070
regulation of rna biosynthetic process GO:2001141 165 0.070
macromolecule modification GO:0043412 218 0.070
cell projection morphogenesis GO:0048858 148 0.069
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.069
neuron differentiation GO:0030182 217 0.067
Fly
organophosphate metabolic process GO:0019637 125 0.067
oxoacid metabolic process GO:0043436 47 0.065
regulation of phosphate metabolic process GO:0019220 81 0.064
transcription dna templated GO:0006351 168 0.064
positive regulation of phosphate metabolic process GO:0045937 56 0.062
positive regulation of multicellular organism growth GO:0040018 352 0.062
negative regulation of transcription dna templated GO:0045892 53 0.062
response to organic substance GO:0010033 131 0.062
body morphogenesis GO:0010171 620 0.061
neurogenesis GO:0022008 236 0.061
Fly
transcription from rna polymerase ii promoter GO:0006366 149 0.061
single organism transport GO:0044765 447 0.059
cellular catabolic process GO:0044248 199 0.058
localization of cell GO:0051674 313 0.057
lipid storage GO:0019915 565 0.056
Worm
regulation of cellular component organization GO:0051128 248 0.055
regulation of gene expression epigenetic GO:0040029 163 0.054
cellular response to dna damage stimulus GO:0006974 41 0.054
organic substance catabolic process GO:1901575 294 0.054
protein complex subunit organization GO:0071822 280 0.053
positive regulation of cellular metabolic process GO:0031325 178 0.052
carboxylic acid metabolic process GO:0019752 34 0.052
regulation of cellular component movement GO:0051270 62 0.050
taxis GO:0042330 128 0.050
positive regulation of response to stimulus GO:0048584 55 0.049
oogenesis GO:0048477 229 0.049
Fly
biosynthetic process GO:0009058 323 0.049
regulation of cellular biosynthetic process GO:0031326 189 0.049
actin filament based process GO:0030029 191 0.048
axon development GO:0061564 163 0.048
muscle tissue development GO:0060537 1 0.048
negative regulation of nucleic acid templated transcription GO:1903507 53 0.048
lipid localization GO:0010876 573 0.047
Worm
nucleotide metabolic process GO:0009117 108 0.047
regulation of phosphorus metabolic process GO:0051174 81 0.047
small molecule metabolic process GO:0044281 186 0.047
protein phosphorylation GO:0006468 85 0.046
negative regulation of metabolic process GO:0009892 240 0.046
nucleobase containing small molecule metabolic process GO:0055086 115 0.045
posttranscriptional regulation of gene expression GO:0010608 166 0.045
Fly
regulation of intracellular signal transduction GO:1902531 77 0.045
intracellular signal transduction GO:0035556 96 0.045
cell cycle process GO:0022402 482 0.045
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.044
organonitrogen compound metabolic process GO:1901564 151 0.044
nucleoside metabolic process GO:0009116 99 0.044
regulation of molecular function GO:0065009 89 0.044
positive regulation of cellular biosynthetic process GO:0031328 109 0.044
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.043
regulation of macromolecule biosynthetic process GO:0010556 189 0.043
single organism localization GO:1902578 518 0.043
positive regulation of macromolecule metabolic process GO:0010604 149 0.043
organic acid metabolic process GO:0006082 47 0.042
ribose phosphate metabolic process GO:0019693 99 0.041
ribonucleotide metabolic process GO:0009259 99 0.041
purine containing compound metabolic process GO:0072521 95 0.040
axonogenesis GO:0007409 102 0.040
cellular response to stress GO:0033554 162 0.039
regulation of developmental growth GO:0048638 389 0.039
establishment of localization in cell GO:0051649 318 0.039
ribonucleoside metabolic process GO:0009119 98 0.038
cytoskeleton organization GO:0007010 339 0.038
organic cyclic compound biosynthetic process GO:1901362 195 0.038
cell proliferation GO:0008283 116 0.037
neuron projection development GO:0031175 187 0.037
skeletal muscle organ development GO:0060538 3 0.037
multi organism reproductive behavior GO:0044705 387 0.037
meiotic chromosome segregation GO:0045132 139 0.037
cellular response to organic substance GO:0071310 119 0.037
gene expression GO:0010467 412 0.037
Fly
cellular amino acid metabolic process GO:0006520 15 0.036
regulation of purine nucleotide metabolic process GO:1900542 37 0.036
chemotaxis GO:0006935 120 0.036
negative regulation of biosynthetic process GO:0009890 65 0.036
signal transduction by phosphorylation GO:0023014 31 0.036
regulation of nucleoside metabolic process GO:0009118 37 0.036
cell projection organization GO:0030030 231 0.035
positive regulation of phosphorus metabolic process GO:0010562 56 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.035
phosphorylation GO:0016310 116 0.035
reproductive behavior GO:0019098 387 0.034
nucleoside triphosphate metabolic process GO:0009141 87 0.034
phagocytosis GO:0006909 115 0.034
cell part morphogenesis GO:0032990 152 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.033
gene silencing by rna GO:0031047 143 0.033
cell development GO:0048468 696 0.033
neuron projection morphogenesis GO:0048812 114 0.032
response to abiotic stimulus GO:0009628 152 0.032
regulation of catalytic activity GO:0050790 78 0.032
purine ribonucleoside metabolic process GO:0046128 92 0.032
intracellular receptor signaling pathway GO:0030522 2 0.031
regulation of protein metabolic process GO:0051246 81 0.031
regulation of cell cycle GO:0051726 194 0.031
regulation of response to wounding GO:1903034 1 0.031
catabolic process GO:0009056 318 0.031
regulation of cellular protein metabolic process GO:0032268 75 0.030
regulation of cell division GO:0051302 142 0.030
chemical homeostasis GO:0048878 29 0.030
carbohydrate derivative metabolic process GO:1901135 141 0.029
muscle structure development GO:0061061 191 0.029
positive regulation of phosphorylation GO:0042327 27 0.029
positive regulation of catalytic activity GO:0043085 59 0.029
protein catabolic process GO:0030163 162 0.029
cellular nitrogen compound biosynthetic process GO:0044271 192 0.029
purine nucleotide metabolic process GO:0006163 95 0.029
negative regulation of gene expression GO:0010629 217 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.029
regulation of cellular catabolic process GO:0031329 51 0.029
establishment of organelle localization GO:0051656 123 0.028
positive regulation of cell cycle GO:0045787 55 0.028
secretion by cell GO:0032940 138 0.028
peptidyl amino acid modification GO:0018193 58 0.028
macromolecular complex subunit organization GO:0043933 320 0.028
multi organism behavior GO:0051705 389 0.028
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.028
negative regulation of rna biosynthetic process GO:1902679 53 0.027
regulation of behavior GO:0050795 97 0.027
regulation of apoptotic signaling pathway GO:2001233 1 0.027
ribonucleoside triphosphate metabolic process GO:0009199 87 0.027
vesicle mediated transport GO:0016192 852 0.027
Worm
regulation of locomotion GO:0040012 161 0.027
cell division GO:0051301 262 0.026
Fly
neuron development GO:0048666 199 0.026
Fly
rna localization GO:0006403 3 0.026
guanosine containing compound metabolic process GO:1901068 49 0.026
negative regulation of cellular process GO:0048523 239 0.026
Fly
cellular macromolecule biosynthetic process GO:0034645 247 0.026
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.026
regulation of transcription dna templated GO:0006355 164 0.025
protein localization GO:0008104 205 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.025
positive regulation of signal transduction GO:0009967 40 0.025
signaling GO:0023052 401 0.025
homeostatic process GO:0042592 51 0.025
posttranscriptional gene silencing GO:0016441 143 0.025
nucleoside triphosphate catabolic process GO:0009143 72 0.024
nucleoside phosphate metabolic process GO:0006753 108 0.023
apoptotic cell clearance GO:0043277 111 0.022
regulation of meiotic cell cycle GO:0051445 136 0.022
phagocytosis engulfment GO:0006911 98 0.022
negative regulation of cellular biosynthetic process GO:0031327 65 0.022
purine nucleoside catabolic process GO:0006152 75 0.022
positive regulation of protein metabolic process GO:0051247 45 0.022
peptidyl serine phosphorylation GO:0018105 20 0.022
mapk cascade GO:0000165 31 0.022
cellular homeostasis GO:0019725 22 0.022
positive regulation of nucleic acid templated transcription GO:1903508 102 0.022
response to temperature stimulus GO:0009266 66 0.021
regulation of nucleotide metabolic process GO:0006140 37 0.021
epithelium development GO:0060429 68 0.021
negative regulation of cellular metabolic process GO:0031324 95 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
cellular component biogenesis GO:0044085 297 0.021
positive regulation of cell communication GO:0010647 69 0.021
positive regulation of transcription dna templated GO:0045893 102 0.020
purine ribonucleotide metabolic process GO:0009150 95 0.020
gene silencing GO:0016458 143 0.020
engulfment of apoptotic cell GO:0043652 94 0.020
organic cyclic compound catabolic process GO:1901361 119 0.019
positive regulation of biosynthetic process GO:0009891 109 0.019
immune response GO:0006955 192 0.019
secretion GO:0046903 147 0.019
cellular response to abiotic stimulus GO:0071214 4 0.019
cellular biosynthetic process GO:0044249 315 0.019
cellular macromolecule localization GO:0070727 75 0.019
positive regulation of signaling GO:0023056 66 0.019
defense response GO:0006952 296 0.019
purine nucleoside metabolic process GO:0042278 92 0.018
negative regulation of cell cycle GO:0045786 53 0.018
positive regulation of intracellular signal transduction GO:1902533 24 0.018
male gamete generation GO:0048232 41 0.018
Fly
nucleoside phosphate catabolic process GO:1901292 77 0.018
actin cytoskeleton organization GO:0030036 184 0.018
single organism catabolic process GO:0044712 129 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.017
cell surface receptor signaling pathway GO:0007166 149 0.017
cytokinesis GO:0000910 80 0.017
multi multicellular organism process GO:0044706 390 0.017
amine metabolic process GO:0009308 15 0.017
purine ribonucleoside catabolic process GO:0046130 75 0.017
ribosome biogenesis GO:0042254 4 0.017
nucleobase containing compound catabolic process GO:0034655 114 0.017
cell morphogenesis involved in differentiation GO:0000904 112 0.016
organonitrogen compound catabolic process GO:1901565 90 0.016
ribonucleotide catabolic process GO:0009261 75 0.016
negative regulation of neurogenesis GO:0050768 4 0.016
cell type specific apoptotic process GO:0097285 4 0.016
muscle cell differentiation GO:0042692 171 0.016
organic substance transport GO:0071702 113 0.016
spermatogenesis GO:0007283 41 0.016
Fly
chromosome segregation GO:0007059 180 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
cellular macromolecular complex assembly GO:0034622 184 0.016
membrane invagination GO:0010324 98 0.015
purine nucleoside triphosphate catabolic process GO:0009146 72 0.015
ion homeostasis GO:0050801 21 0.015
regulation of neurogenesis GO:0050767 40 0.015
Fly
cellular nitrogen compound catabolic process GO:0044270 119 0.015
posttranscriptional gene silencing by rna GO:0035194 143 0.015
peptidyl serine modification GO:0018209 20 0.015
response to oxygen containing compound GO:1901700 44 0.015
positive regulation of protein modification process GO:0031401 29 0.015
regulation of phosphorylation GO:0042325 45 0.015
ribonucleoside catabolic process GO:0042454 77 0.015
ras protein signal transduction GO:0007265 31 0.014
regulation of mitotic cell cycle GO:0007346 76 0.014
head development GO:0060322 1 0.014
purine nucleoside triphosphate metabolic process GO:0009144 87 0.014
tube development GO:0035295 126 0.014
positive regulation of molecular function GO:0044093 61 0.014
muscle organ development GO:0007517 26 0.014
oocyte axis specification GO:0007309 2 0.014
cell fate commitment GO:0045165 139 0.014
small gtpase mediated signal transduction GO:0007264 32 0.014
rna interference GO:0016246 137 0.014
regulation of cell migration GO:0030334 55 0.013
regulation of localization GO:0032879 194 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
neuron projection guidance GO:0097485 82 0.013
cellular macromolecule catabolic process GO:0044265 73 0.013
regulation of nucleic acid templated transcription GO:1903506 165 0.013
aromatic compound catabolic process GO:0019439 116 0.013
regulation of cellular response to stress GO:0080135 19 0.013
nucleobase containing compound metabolic process GO:0006139 406 0.013
striated muscle cell differentiation GO:0051146 158 0.013
regulation of purine nucleotide catabolic process GO:0033121 35 0.013
nucleoside catabolic process GO:0009164 78 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.013
atp metabolic process GO:0046034 42 0.013
positive regulation of cell migration GO:0030335 3 0.012
cellular response to endogenous stimulus GO:0071495 32 0.012
glycosyl compound catabolic process GO:1901658 79 0.012
monocarboxylic acid metabolic process GO:0032787 22 0.012
modification dependent protein catabolic process GO:0019941 32 0.012
anatomical structure formation involved in morphogenesis GO:0048646 250 0.012
muscle cell development GO:0055001 158 0.012
single organism biosynthetic process GO:0044711 91 0.012
regulation of gtp catabolic process GO:0033124 32 0.012
molting cycle GO:0042303 281 0.012
response to heat GO:0009408 50 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.012
microtubule based process GO:0007017 182 0.012
female meiotic division GO:0007143 17 0.011
detection of external stimulus GO:0009581 4 0.011
regulation of cell proliferation GO:0042127 105 0.011
cellular amine metabolic process GO:0044106 15 0.011
oocyte construction GO:0007308 2 0.011
positive regulation of nucleotide metabolic process GO:0045981 28 0.011
positive regulation of nucleoside metabolic process GO:0045979 28 0.011
negative regulation of cell communication GO:0010648 61 0.011
pattern specification process GO:0007389 59 0.011
cellular response to oxygen containing compound GO:1901701 21 0.011
cytoskeleton dependent cytokinesis GO:0061640 35 0.011
positive regulation of cellular protein catabolic process GO:1903364 3 0.010
cellular protein localization GO:0034613 75 0.010
negative regulation of response to stimulus GO:0048585 73 0.010
oocyte differentiation GO:0009994 45 0.010
cellular protein catabolic process GO:0044257 37 0.010

let-70 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org