Caenorhabditis elegans

69 known processes

gcy-28 (CELE_T01A4.1)

Protein GCY-28

gcy-28 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vesicle mediated transport GO:0016192 852 0.213
establishment of localization GO:0051234 1171 0.208
post embryonic development GO:0009791 2152 0.205
Worm
cell development GO:0048468 696 0.193
Mouse Worm
embryo development ending in birth or egg hatching GO:0009792 2992 0.182
Worm
transport GO:0006810 1093 0.171
determination of adult lifespan GO:0008340 812 0.165
Worm
female gamete generation GO:0007292 254 0.164
Mouse
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.163
Mouse
organ development GO:0048513 1102 0.162
Mouse
embryo development GO:0009790 3052 0.157
Worm
multicellular organismal reproductive process GO:0048609 815 0.155
Mouse
single organism organelle organization GO:1902589 501 0.153
sexual reproduction GO:0019953 546 0.152
Mouse
endocytosis GO:0006897 819 0.150
death GO:0016265 547 0.150
multicellular organismal aging GO:0010259 812 0.149
Worm
aging GO:0007568 812 0.148
Worm
regulation of developmental process GO:0050793 684 0.144
Mouse Worm
signaling GO:0023052 401 0.143
Human Mouse Rat Worm
regulation of multicellular organismal process GO:0051239 726 0.141
Mouse Worm
synaptic transmission GO:0007268 106 0.139
programmed cell death GO:0012501 500 0.138
multicellular organism reproduction GO:0032504 819 0.126
Mouse
cell death GO:0008219 547 0.121
behavior GO:0007610 527 0.119
oviposition GO:0018991 364 0.119
regulation of biological quality GO:0065008 741 0.117
Worm
multi organism reproductive process GO:0044703 867 0.117
Mouse
negative regulation of biological process GO:0048519 567 0.116
Mouse Rat
germ cell development GO:0007281 351 0.114
Mouse
oogenesis GO:0048477 229 0.113
Mouse
reproductive system development GO:0061458 850 0.109
single organism localization GO:1902578 518 0.109
macromolecule localization GO:0033036 771 0.109
organelle organization GO:0006996 783 0.108
apoptotic process GO:0006915 478 0.107
gamete generation GO:0007276 461 0.104
Mouse
positive regulation of multicellular organismal process GO:0051240 417 0.103
system process GO:0003008 136 0.099
single organism signaling GO:0044700 401 0.097
Human Mouse Rat Worm
receptor mediated endocytosis GO:0006898 715 0.096
cell cycle GO:0007049 526 0.094
Mouse
locomotion GO:0040011 1634 0.092
protein metabolic process GO:0019538 422 0.089
cytoskeleton organization GO:0007010 339 0.089
single organism transport GO:0044765 447 0.087
single organism reproductive process GO:0044702 1196 0.087
Mouse
nervous system development GO:0007399 253 0.086
Worm
development of primary sexual characteristics GO:0045137 840 0.085
regulation of macromolecule metabolic process GO:0060255 421 0.082
multi organism reproductive behavior GO:0044705 387 0.082
catabolic process GO:0009056 318 0.080
signal transduction GO:0007165 317 0.079
Human Mouse Rat Worm
g protein coupled receptor signaling pathway GO:0007186 46 0.079
body morphogenesis GO:0010171 620 0.079
cellular component morphogenesis GO:0032989 318 0.079
Worm
regulation of signaling GO:0023051 172 0.077
Worm
positive regulation of developmental process GO:0051094 408 0.077
gonad development GO:0008406 840 0.077
lipid localization GO:0010876 573 0.077
reproductive behavior GO:0019098 387 0.076
maintenance of location GO:0051235 580 0.075
phosphorus metabolic process GO:0006793 232 0.074
regulation of metabolic process GO:0019222 478 0.073
Rat
secretion GO:0046903 147 0.073
negative regulation of developmental process GO:0051093 227 0.072
Mouse
regulation of response to stimulus GO:0048583 243 0.072
Worm
multicellular organism growth GO:0035264 385 0.071
regulation of cation channel activity GO:2001257 3 0.071
sex differentiation GO:0007548 909 0.071
regulation of growth GO:0040008 409 0.069
Worm
multicellular organismal reproductive behavior GO:0033057 384 0.069
multi multicellular organism process GO:0044706 390 0.069
lipid storage GO:0019915 565 0.068
response to organic substance GO:0010033 131 0.068
Human Worm
regulation of synaptic transmission GO:0050804 34 0.067
genitalia development GO:0048806 741 0.066
regulation of multicellular organism growth GO:0040014 373 0.066
growth GO:0040007 562 0.065
Worm
multi organism behavior GO:0051705 389 0.065
positive regulation of growth GO:0045927 369 0.065
macromolecule modification GO:0043412 218 0.064
cell cycle process GO:0022402 482 0.063
cellular protein metabolic process GO:0044267 279 0.063
cell projection organization GO:0030030 231 0.061
Worm
response to chemical GO:0042221 356 0.061
neuron development GO:0048666 199 0.060
Worm
macromolecular complex subunit organization GO:0043933 320 0.059
cellular component assembly involved in morphogenesis GO:0010927 183 0.059
phosphate containing compound metabolic process GO:0006796 232 0.059
biosynthetic process GO:0009058 323 0.059
organic substance catabolic process GO:1901575 294 0.058
positive regulation of developmental growth GO:0048639 354 0.058
response to external stimulus GO:0009605 289 0.057
regulation of cell differentiation GO:0045595 81 0.057
Mouse Worm
protein modification process GO:0036211 207 0.057
reproductive structure development GO:0048608 850 0.056
hermaphrodite genitalia development GO:0040035 734 0.055
anatomical structure formation involved in morphogenesis GO:0048646 250 0.055
developmental process involved in reproduction GO:0003006 1165 0.054
Mouse
protein complex subunit organization GO:0071822 280 0.054
ion transport GO:0006811 113 0.054
cellular component biogenesis GO:0044085 297 0.052
negative regulation of cellular process GO:0048523 239 0.052
Mouse Rat
regulation of signal transduction GO:0009966 135 0.051
Worm
organic substance biosynthetic process GO:1901576 323 0.049
regulation of transport GO:0051049 91 0.048
striated muscle cell development GO:0055002 157 0.048
regulation of localization GO:0032879 194 0.048
cellular macromolecular complex assembly GO:0034622 184 0.047
pattern specification process GO:0007389 59 0.046
actin cytoskeleton organization GO:0030036 184 0.045
establishment of localization in cell GO:0051649 318 0.045
embryonic morphogenesis GO:0048598 152 0.045
negative regulation of multicellular organismal process GO:0051241 236 0.044
Mouse
striated muscle cell differentiation GO:0051146 158 0.044
cellular protein modification process GO:0006464 207 0.044
feeding behavior GO:0007631 70 0.043
regulation of neuromuscular synaptic transmission GO:1900073 1 0.043
cell division GO:0051301 262 0.043
small molecule metabolic process GO:0044281 186 0.042
actin filament based process GO:0030029 191 0.042
muscle cell differentiation GO:0042692 171 0.041
regulation of reproductive process GO:2000241 66 0.041
Mouse
phosphorylation GO:0016310 116 0.040
cell surface receptor signaling pathway GO:0007166 149 0.040
Human Rat Worm
striated muscle myosin thick filament assembly GO:0071688 138 0.039
nucleobase containing compound biosynthetic process GO:0034654 184 0.039
regulation of primary metabolic process GO:0080090 292 0.039
Rat
taxis GO:0042330 128 0.039
muscle cell development GO:0055001 158 0.039
secretion by cell GO:0032940 138 0.039
myofibril assembly GO:0030239 154 0.039
eating behavior GO:0042755 59 0.038
regulation of multi organism process GO:0043900 69 0.038
Mouse
regulation of developmental growth GO:0048638 389 0.037
Worm
macromolecular complex assembly GO:0065003 193 0.037
pharyngeal pumping GO:0043050 58 0.037
regulation of feeding behavior GO:0060259 38 0.037
regulation of secretion GO:0051046 29 0.036
regulation of multicellular organismal development GO:2000026 317 0.036
Worm
cellular component assembly GO:0022607 293 0.036
developmental growth GO:0048589 412 0.036
Worm
gene expression GO:0010467 412 0.036
dauer larval development GO:0040024 92 0.035
Worm
aromatic compound biosynthetic process GO:0019438 192 0.035
regulation of cellular component organization GO:0051128 248 0.035
Worm
negative regulation of macromolecule metabolic process GO:0010605 229 0.035
head development GO:0060322 1 0.035
regulation of cell development GO:0060284 49 0.035
Mouse Worm
cellular localization GO:0051641 360 0.035
regulation of ion transport GO:0043269 39 0.034
defecation rhythm GO:0035882 3 0.034
neuron projection development GO:0031175 187 0.034
Worm
negative regulation of metabolic process GO:0009892 240 0.034
transmembrane transport GO:0055085 110 0.034
neuron projection morphogenesis GO:0048812 114 0.033
Worm
protein complex assembly GO:0006461 186 0.033
response to wounding GO:0009611 4 0.032
molting cycle GO:0042303 281 0.032
generation of neurons GO:0048699 235 0.032
Worm
organonitrogen compound metabolic process GO:1901564 151 0.032
myosin filament assembly GO:0031034 138 0.031
positive regulation of cellular process GO:0048522 332 0.031
Rat Worm
organelle localization GO:0051640 127 0.031
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.031
localization of cell GO:0051674 313 0.031
regulation of phosphate metabolic process GO:0019220 81 0.030
Rat
nucleobase containing compound metabolic process GO:0006139 406 0.029
cellular macromolecule biosynthetic process GO:0034645 247 0.029
regulation of cell communication GO:0010646 176 0.029
Worm
ion transmembrane transport GO:0034220 91 0.029
actomyosin structure organization GO:0031032 154 0.029
regulation of gene expression GO:0010468 366 0.029
cell projection morphogenesis GO:0048858 148 0.029
Worm
rna metabolic process GO:0016070 228 0.029
muscle structure development GO:0061061 191 0.029
neurogenesis GO:0022008 236 0.029
Worm
organelle assembly GO:0070925 214 0.029
cellular nitrogen compound biosynthetic process GO:0044271 192 0.029
protein catabolic process GO:0030163 162 0.028
oocyte development GO:0048599 44 0.028
Mouse
cellular component movement GO:0006928 388 0.028
macromolecule biosynthetic process GO:0009059 250 0.028
regulation of cell division GO:0051302 142 0.028
regulation of cell cycle GO:0051726 194 0.028
Mouse
heterocycle biosynthetic process GO:0018130 187 0.028
response to abiotic stimulus GO:0009628 152 0.027
calcium mediated signaling GO:0019722 3 0.027
intracellular signal transduction GO:0035556 96 0.027
Rat
regulation of neurotransmitter levels GO:0001505 36 0.027
regulation of organelle organization GO:0033043 164 0.027
organelle fission GO:0048285 363 0.027
cell migration GO:0016477 306 0.027
regulation of behavior GO:0050795 97 0.027
cellular response to stress GO:0033554 162 0.026
negative regulation of response to stimulus GO:0048585 73 0.026
cellular response to organic substance GO:0071310 119 0.026
Human Worm
oxoacid metabolic process GO:0043436 47 0.026
regulation of intracellular signal transduction GO:1902531 77 0.026
negative regulation of ion transmembrane transporter activity GO:0032413 3 0.026
muscle tissue development GO:0060537 1 0.026
cellular protein complex assembly GO:0043623 178 0.025
vulval development GO:0040025 333 0.025
neuron differentiation GO:0030182 217 0.025
Worm
positive regulation of multicellular organism growth GO:0040018 352 0.025
defense response GO:0006952 296 0.025
carboxylic acid metabolic process GO:0019752 34 0.025
response to other organism GO:0051707 101 0.024
regulation of cytoplasmic transport GO:1903649 3 0.024
myosin filament organization GO:0031033 138 0.024
neurotransmitter transport GO:0006836 32 0.024
positive regulation of neurogenesis GO:0050769 4 0.024
carbohydrate derivative metabolic process GO:1901135 141 0.023
regulation of rna metabolic process GO:0051252 173 0.023
post embryonic organ development GO:0048569 336 0.023
nucleic acid metabolic process GO:0090304 299 0.023
axon development GO:0061564 163 0.022
Worm
negative regulation of cation channel activity GO:2001258 2 0.022
cell maturation GO:0048469 26 0.022
Mouse
transcription dna templated GO:0006351 168 0.022
protein phosphorylation GO:0006468 85 0.022
regulation of response to wounding GO:1903034 1 0.022
cell type specific apoptotic process GO:0097285 4 0.022
cell motility GO:0048870 313 0.022
regulation of cell cycle process GO:0010564 145 0.022
cellular biosynthetic process GO:0044249 315 0.022
regulation of transcription dna templated GO:0006355 164 0.021
regulation of lipid metabolic process GO:0019216 4 0.021
positive regulation of signaling GO:0023056 66 0.021
Worm
regulation of nitrogen compound metabolic process GO:0051171 222 0.021
Rat
regulation of cellular ketone metabolic process GO:0010565 3 0.021
membrane organization GO:0061024 135 0.020
macromolecule catabolic process GO:0009057 202 0.020
organic acid metabolic process GO:0006082 47 0.020
organic substance transport GO:0071702 113 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
regulation of post embryonic development GO:0048580 260 0.020
immune response GO:0006955 192 0.020
negative regulation of ion transport GO:0043271 7 0.020
response to biotic stimulus GO:0009607 101 0.019
excretion GO:0007588 49 0.019
cell cell signaling GO:0007267 118 0.019
nucleic acid templated transcription GO:0097659 169 0.019
meiotic cell cycle GO:0051321 335 0.019
Mouse
meiotic nuclear division GO:0007126 300 0.019
negative regulation of transporter activity GO:0032410 3 0.019
cellular ketone metabolic process GO:0042180 14 0.019
regulation of nematode larval development GO:0061062 260 0.019
positive regulation of response to stimulus GO:0048584 55 0.019
Worm
regulation of nucleic acid templated transcription GO:1903506 165 0.018
negative regulation of ion transmembrane transport GO:0034766 3 0.018
response to external biotic stimulus GO:0043207 101 0.018
cellular amino acid metabolic process GO:0006520 15 0.018
regulation of cellular metabolic process GO:0031323 305 0.018
Rat
single organism catabolic process GO:0044712 129 0.018
regulation of gene expression epigenetic GO:0040029 163 0.018
cell proliferation GO:0008283 116 0.018
Rat
phagocytosis GO:0006909 115 0.018
nitrogen compound transport GO:0071705 49 0.018
regulation of locomotion GO:0040012 161 0.018
sensory organ morphogenesis GO:0090596 2 0.017
positive regulation of transport GO:0051050 32 0.017
protein complex biogenesis GO:0070271 186 0.017
rna interference GO:0016246 137 0.017
negative regulation of transmembrane transport GO:0034763 3 0.017
negative regulation of signaling GO:0023057 61 0.017
gene silencing by rna GO:0031047 143 0.017
cellular catabolic process GO:0044248 199 0.017
posttranscriptional gene silencing GO:0016441 143 0.017
positive regulation of cell communication GO:0010647 69 0.017
Worm
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
regulation of nervous system development GO:0051960 41 0.016
Worm
negative regulation of gene expression GO:0010629 217 0.016
regulation of protein metabolic process GO:0051246 81 0.016
regulation of molecular function GO:0065009 89 0.016
regulation of macromolecule biosynthetic process GO:0010556 189 0.016
ribose phosphate metabolic process GO:0019693 99 0.016
cell morphogenesis GO:0000902 163 0.016
Worm
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.016
Rat
regulation of oviposition GO:0046662 43 0.016
positive regulation of locomotion GO:0040017 42 0.016
negative regulation of cellular metabolic process GO:0031324 95 0.016
innate immune response GO:0045087 190 0.016
defense response to other organism GO:0098542 100 0.016
rna biosynthetic process GO:0032774 169 0.016
amine metabolic process GO:0009308 15 0.016
developmental maturation GO:0021700 26 0.016
Mouse
posttranscriptional gene silencing by rna GO:0035194 143 0.015
purine ribonucleotide metabolic process GO:0009150 95 0.015
positive regulation of cell migration GO:0030335 3 0.015
memory GO:0007613 3 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.015
regulation of vulval development GO:0040028 248 0.015
establishment of organelle localization GO:0051656 123 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.015
purine nucleotide metabolic process GO:0006163 95 0.015
regulation of neurogenesis GO:0050767 40 0.015
Worm
cell morphogenesis involved in differentiation GO:0000904 112 0.015
Worm
negative regulation of nematode larval development GO:0061064 208 0.015
heterocycle catabolic process GO:0046700 119 0.015
response to bacterium GO:0009617 86 0.015
neurological system process GO:0050877 53 0.015
phagocytosis engulfment GO:0006911 98 0.015
posttranscriptional regulation of gene expression GO:0010608 166 0.015
regulation of cellular protein metabolic process GO:0032268 75 0.015
gene silencing GO:0016458 143 0.014
glycosyl compound catabolic process GO:1901658 79 0.014
establishment of vesicle localization GO:0051650 23 0.014
cognition GO:0050890 27 0.014
Worm
epithelium development GO:0060429 68 0.014
protein localization GO:0008104 205 0.014
negative regulation of signal transduction GO:0009968 60 0.014
regulation of anatomical structure size GO:0090066 46 0.014
Worm
ribonucleotide catabolic process GO:0009261 75 0.014
intercellular transport GO:0010496 1 0.014
regulation of rna biosynthetic process GO:2001141 165 0.014
long term memory GO:0007616 2 0.013
neuromuscular junction development GO:0007528 2 0.013
cuticle development GO:0042335 100 0.013
neurotransmitter secretion GO:0007269 26 0.013
apoptotic cell clearance GO:0043277 111 0.013
cellular nitrogen compound catabolic process GO:0044270 119 0.013
regulation of apoptotic signaling pathway GO:2001233 1 0.013
nucleoside phosphate metabolic process GO:0006753 108 0.013
regeneration GO:0031099 4 0.013
ribonucleotide metabolic process GO:0009259 99 0.013
defecation GO:0030421 47 0.013
regulation of phosphorylation GO:0042325 45 0.013
synaptic vesicle transport GO:0048489 21 0.013
negative regulation of cell communication GO:0010648 61 0.013
epithelial tube morphogenesis GO:0060562 1 0.013
negative regulation of post embryonic development GO:0048581 208 0.013
cellular amine metabolic process GO:0044106 15 0.013
regulation of cell motility GO:2000145 57 0.013
inductive cell migration GO:0040039 145 0.013
negative regulation of neurogenesis GO:0050768 4 0.012
regulation of hormone secretion GO:0046883 2 0.012
single fertilization GO:0007338 61 0.012
regulation of phosphorus metabolic process GO:0051174 81 0.012
Rat
mitotic cell cycle process GO:1903047 194 0.012
single organism biosynthetic process GO:0044711 91 0.012
cell substrate adhesion GO:0031589 1 0.012
engulfment of apoptotic cell GO:0043652 94 0.012
cell part morphogenesis GO:0032990 152 0.012
Worm
nucleobase containing small molecule metabolic process GO:0055086 115 0.012
rna localization GO:0006403 3 0.012
nucleoside metabolic process GO:0009116 99 0.012
regulation of cellular biosynthetic process GO:0031326 189 0.012
Rat
positive regulation of vulval development GO:0040026 52 0.012
regulation of meiosis GO:0040020 94 0.012
single organism behavior GO:0044708 83 0.012
organophosphate metabolic process GO:0019637 125 0.012
intracellular transport GO:0046907 77 0.012
organic cyclic compound biosynthetic process GO:1901362 195 0.012
cation transport GO:0006812 78 0.012
lipid metabolic process GO:0006629 77 0.012
positive regulation of secretion by cell GO:1903532 14 0.012
collagen and cuticulin based cuticle development GO:0040002 99 0.012
spindle organization GO:0007051 92 0.012
nucleotide metabolic process GO:0009117 108 0.012
chemotaxis GO:0006935 120 0.012
regulation of cell proliferation GO:0042127 105 0.012
Rat
positive regulation of secretion GO:0051047 17 0.011
regulation of ion transmembrane transport GO:0034765 19 0.011
regulation of cell migration GO:0030334 55 0.011
fertilization GO:0009566 63 0.011
microtubule based process GO:0007017 182 0.011
regulation of cell death GO:0010941 65 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
learning or memory GO:0007611 27 0.011
Worm
positive regulation of neuron differentiation GO:0045666 4 0.011
adult behavior GO:0030534 3 0.011
positive regulation of intracellular transport GO:0032388 2 0.011
negative regulation of vulval development GO:0040027 206 0.011
regulation of nuclear division GO:0051783 115 0.011
membrane invagination GO:0010324 98 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.011
Rat
regulation of biosynthetic process GO:0009889 189 0.011
Rat
negative regulation of gene expression epigenetic GO:0045814 2 0.011
regulation of defecation rhythm GO:2000746 3 0.011
cytosolic calcium ion homeostasis GO:0051480 2 0.011
purine containing compound catabolic process GO:0072523 75 0.011
positive regulation of cellular metabolic process GO:0031325 178 0.011
Rat
axonogenesis GO:0007409 102 0.011
Worm
organic cyclic compound catabolic process GO:1901361 119 0.011
regulation of calcium ion transport GO:0051924 3 0.011
regulation of catalytic activity GO:0050790 78 0.011
regulation of cellular component size GO:0032535 40 0.011
Worm
regulation of system process GO:0044057 27 0.011
ribonucleoside metabolic process GO:0009119 98 0.011
positive regulation of synaptic transmission GO:0050806 24 0.010
mitotic nuclear division GO:0007067 89 0.010
peptidyl serine modification GO:0018209 20 0.010
purine ribonucleoside catabolic process GO:0046130 75 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.010
response to inorganic substance GO:0010035 50 0.010
hormone transport GO:0009914 2 0.010
metal ion transport GO:0030001 49 0.010
signal transduction by phosphorylation GO:0023014 31 0.010
homeostatic process GO:0042592 51 0.010
neuropeptide signaling pathway GO:0007218 13 0.010
regulation of oocyte maturation GO:1900193 7 0.010
Mouse
muscle fiber development GO:0048747 2 0.010
enzyme linked receptor protein signaling pathway GO:0007167 50 0.010
Human Worm

gcy-28 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
Human
nervous system disease DOID:863 0 0.012