Caenorhabditis elegans

24 known processes

knl-2 (CELE_K06A5.4)

Protein KNL-2

knl-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.690
meiotic cell cycle GO:0051321 335 0.646
Worm
cell cycle GO:0007049 526 0.633
Worm
reproductive system development GO:0061458 850 0.559
Worm
embryo development GO:0009790 3052 0.559
sex differentiation GO:0007548 909 0.531
Worm
meiotic cell cycle process GO:1903046 170 0.412
single organism organelle organization GO:1902589 501 0.412
developmental process involved in reproduction GO:0003006 1165 0.283
Worm
meiotic nuclear division GO:0007126 300 0.282
Worm
apoptotic process GO:0006915 478 0.269
cell cycle process GO:0022402 482 0.269
Worm
gonad development GO:0008406 840 0.266
Worm
chromosome segregation GO:0007059 180 0.263
reproductive structure development GO:0048608 850 0.249
Worm
meiotic chromosome segregation GO:0045132 139 0.226
cellular localization GO:0051641 360 0.221
hermaphrodite genitalia development GO:0040035 734 0.219
Worm
organelle fission GO:0048285 363 0.194
Worm
regulation of microtubule cytoskeleton organization GO:0070507 21 0.189
cellular component assembly GO:0022607 293 0.171
chromosome organization involved in meiosis GO:0070192 25 0.170
nucleobase containing compound metabolic process GO:0006139 406 0.169
establishment of localization GO:0051234 1171 0.157
organelle organization GO:0006996 783 0.153
organic substance biosynthetic process GO:1901576 323 0.151
chromosome organization GO:0051276 104 0.150
programmed cell death GO:0012501 500 0.148
regulation of organelle organization GO:0033043 164 0.142
Worm
single organism reproductive process GO:0044702 1196 0.133
Worm
organ development GO:0048513 1102 0.129
Worm
cytoskeleton organization GO:0007010 339 0.128
nucleic acid metabolic process GO:0090304 299 0.128
cell death GO:0008219 547 0.125
macromolecule localization GO:0033036 771 0.118
locomotion GO:0040011 1634 0.111
development of primary sexual characteristics GO:0045137 840 0.098
Worm
oviposition GO:0018991 364 0.093
regulation of nitrogen compound metabolic process GO:0051171 222 0.091
mitotic nuclear division GO:0007067 89 0.089
macromolecular complex subunit organization GO:0043933 320 0.084
establishment of localization in cell GO:0051649 318 0.083
genitalia development GO:0048806 741 0.082
Worm
organelle assembly GO:0070925 214 0.081
regulation of macromolecule biosynthetic process GO:0010556 189 0.081
multi organism reproductive process GO:0044703 867 0.080
maintenance of location GO:0051235 580 0.078
multicellular organismal reproductive process GO:0048609 815 0.074
protein localization GO:0008104 205 0.072
protein metabolic process GO:0019538 422 0.069
multicellular organism reproduction GO:0032504 819 0.069
polar body extrusion after meiotic divisions GO:0040038 14 0.068
dna metabolic process GO:0006259 74 0.068
mitotic cell cycle process GO:1903047 194 0.067
regulation of cellular component organization GO:0051128 248 0.066
Worm
multicellular organismal reproductive behavior GO:0033057 384 0.065
body morphogenesis GO:0010171 620 0.063
rna localization GO:0006403 3 0.063
gamete generation GO:0007276 461 0.062
protein complex biogenesis GO:0070271 186 0.060
chromatin organization GO:0006325 32 0.060
neuron projection morphogenesis GO:0048812 114 0.060
regulation of chromosome organization GO:0033044 20 0.059
negative regulation of gene expression GO:0010629 217 0.059
lipid storage GO:0019915 565 0.059
single fertilization GO:0007338 61 0.059
single organism localization GO:1902578 518 0.058
microtubule based process GO:0007017 182 0.058
cell morphogenesis GO:0000902 163 0.058
transport GO:0006810 1093 0.057
cellular component biogenesis GO:0044085 297 0.057
membrane organization GO:0061024 135 0.056
sexual reproduction GO:0019953 546 0.056
aromatic compound biosynthetic process GO:0019438 192 0.056
lipid localization GO:0010876 573 0.055
organic substance transport GO:0071702 113 0.055
regulation of biological quality GO:0065008 741 0.054
negative regulation of biological process GO:0048519 567 0.052
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.050
cell division GO:0051301 262 0.050
Worm
organelle localization GO:0051640 127 0.048
maintenance of protein location in cell GO:0032507 12 0.047
cellular component morphogenesis GO:0032989 318 0.046
death GO:0016265 547 0.046
intracellular receptor signaling pathway GO:0030522 2 0.046
sister chromatid segregation GO:0000819 46 0.046
cell motility GO:0048870 313 0.046
spindle assembly GO:0051225 8 0.045
mitotic sister chromatid segregation GO:0000070 38 0.045
cell migration GO:0016477 306 0.044
establishment of organelle localization GO:0051656 123 0.044
maintenance of protein location GO:0045185 15 0.044
regulation of cell division GO:0051302 142 0.043
Worm
phosphate containing compound metabolic process GO:0006796 232 0.043
microtubule polymerization or depolymerization GO:0031109 22 0.043
cellular macromolecule biosynthetic process GO:0034645 247 0.042
regulation of cellular metabolic process GO:0031323 305 0.042
cellular protein metabolic process GO:0044267 279 0.041
cellular protein localization GO:0034613 75 0.039
protein complex subunit organization GO:0071822 280 0.039
organic substance catabolic process GO:1901575 294 0.039
vesicle mediated transport GO:0016192 852 0.038
cell development GO:0048468 696 0.038
actin filament based process GO:0030029 191 0.038
endocytosis GO:0006897 819 0.037
regulation of cell cycle process GO:0010564 145 0.037
Worm
protein complex assembly GO:0006461 186 0.037
regulation of gene expression GO:0010468 366 0.036
inductive cell migration GO:0040039 145 0.035
cellular biosynthetic process GO:0044249 315 0.035
germ cell development GO:0007281 351 0.035
phosphorus metabolic process GO:0006793 232 0.035
cellular nitrogen compound biosynthetic process GO:0044271 192 0.035
regulation of cytoplasmic transport GO:1903649 3 0.034
catabolic process GO:0009056 318 0.034
transcription dna templated GO:0006351 168 0.034
regulation of biosynthetic process GO:0009889 189 0.033
nucleic acid templated transcription GO:0097659 169 0.033
behavior GO:0007610 527 0.033
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.033
regulation of metabolic process GO:0019222 478 0.033
rna metabolic process GO:0016070 228 0.032
multi organism reproductive behavior GO:0044705 387 0.032
dna packaging GO:0006323 7 0.032
positive regulation of developmental growth GO:0048639 354 0.032
Worm
regulation of cellular biosynthetic process GO:0031326 189 0.032
intracellular signal transduction GO:0035556 96 0.030
organic cyclic compound biosynthetic process GO:1901362 195 0.029
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.029
multi organism behavior GO:0051705 389 0.028
cellular protein modification process GO:0006464 207 0.028
posttranscriptional regulation of gene expression GO:0010608 166 0.027
cellular protein complex assembly GO:0043623 178 0.027
negative regulation of gene expression epigenetic GO:0045814 2 0.027
canonical wnt signaling pathway GO:0060070 3 0.026
regulation of nucleocytoplasmic transport GO:0046822 3 0.026
single organism transport GO:0044765 447 0.025
spindle assembly involved in mitosis GO:0090307 6 0.025
regulation of phosphate metabolic process GO:0019220 81 0.025
gene silencing GO:0016458 143 0.025
regulation of primary metabolic process GO:0080090 292 0.025
multicellular organismal aging GO:0010259 812 0.025
posttranscriptional gene silencing by rna GO:0035194 143 0.025
neuron differentiation GO:0030182 217 0.024
cellular nitrogen compound catabolic process GO:0044270 119 0.023
regulation of developmental process GO:0050793 684 0.023
Worm
regulation of developmental growth GO:0048638 389 0.023
Worm
cellular macromolecule localization GO:0070727 75 0.023
regulation of transcription dna templated GO:0006355 164 0.023
single organism signaling GO:0044700 401 0.023
cellular component movement GO:0006928 388 0.022
post embryonic development GO:0009791 2152 0.022
macromolecule biosynthetic process GO:0009059 250 0.022
organonitrogen compound metabolic process GO:1901564 151 0.022
multi multicellular organism process GO:0044706 390 0.022
regulation of protein localization GO:0032880 50 0.021
nuclear migration GO:0007097 54 0.021
regulation of microtubule based process GO:0032886 21 0.021
regulation of apoptotic signaling pathway GO:2001233 1 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.020
posttranscriptional gene silencing GO:0016441 143 0.020
regulation of gene expression epigenetic GO:0040029 163 0.020
regulation of response to stimulus GO:0048583 243 0.020
cellular macromolecular complex assembly GO:0034622 184 0.019
meiotic cytokinesis GO:0033206 15 0.019
female gamete generation GO:0007292 254 0.019
localization of cell GO:0051674 313 0.019
determination of adult lifespan GO:0008340 812 0.019
attachment of mitotic spindle microtubules to kinetochore GO:0051315 6 0.019
regulation of growth GO:0040008 409 0.019
Worm
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.019
Worm
receptor mediated endocytosis GO:0006898 715 0.019
cell type specific apoptotic process GO:0097285 4 0.019
vulval development GO:0040025 333 0.018
Worm
negative regulation of cellular component organization GO:0051129 33 0.018
cell projection organization GO:0030030 231 0.018
multicellular organism growth GO:0035264 385 0.018
Worm
negative regulation of metabolic process GO:0009892 240 0.018
negative regulation of macromolecule metabolic process GO:0010605 229 0.018
regulation of nucleic acid templated transcription GO:1903506 165 0.018
ras protein signal transduction GO:0007265 31 0.017
carboxylic acid metabolic process GO:0019752 34 0.017
cellular catabolic process GO:0044248 199 0.017
chromatin assembly or disassembly GO:0006333 1 0.017
growth GO:0040007 562 0.017
Worm
small molecule metabolic process GO:0044281 186 0.016
aging GO:0007568 812 0.016
regulation of localization GO:0032879 194 0.016
generation of neurons GO:0048699 235 0.016
regulation of cell death GO:0010941 65 0.016
macromolecule modification GO:0043412 218 0.016
chromatin modification GO:0016568 32 0.016
response to chemical GO:0042221 356 0.016
anatomical structure formation involved in morphogenesis GO:0048646 250 0.016
nucleus organization GO:0006997 38 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.015
positive regulation of multicellular organismal process GO:0051240 417 0.015
Worm
macromolecular complex assembly GO:0065003 193 0.015
rna interference GO:0016246 137 0.015
positive regulation of developmental process GO:0051094 408 0.014
Worm
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.014
actomyosin structure organization GO:0031032 154 0.014
oocyte axis specification GO:0007309 2 0.014
reproductive behavior GO:0019098 387 0.014
regulation of chromatin modification GO:1903308 2 0.014
cellular response to stress GO:0033554 162 0.014
neuron projection development GO:0031175 187 0.014
covalent chromatin modification GO:0016569 30 0.014
microtubule cytoskeleton organization involved in mitosis GO:1902850 12 0.014
positive regulation of signaling GO:0023056 66 0.014
regulation of cellular localization GO:0060341 42 0.013
regulation of mitotic spindle organization GO:0060236 3 0.013
male sex differentiation GO:0046661 86 0.013
cell morphogenesis involved in differentiation GO:0000904 112 0.013
cell part morphogenesis GO:0032990 152 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
secretion by cell GO:0032940 138 0.013
regulation of cell cycle GO:0051726 194 0.012
Worm
biosynthetic process GO:0009058 323 0.012
male anatomical structure morphogenesis GO:0090598 78 0.012
chromatin assembly GO:0031497 1 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
protein polymerization GO:0051258 26 0.012
organic acid metabolic process GO:0006082 47 0.012
heterocycle biosynthetic process GO:0018130 187 0.012
transmembrane transport GO:0055085 110 0.012
small gtpase mediated signal transduction GO:0007264 32 0.012
cytoskeleton dependent cytokinesis GO:0061640 35 0.012
rna transport GO:0050658 3 0.012
positive regulation of multicellular organism growth GO:0040018 352 0.012
Worm
oocyte construction GO:0007308 2 0.012
regulation of molecular function GO:0065009 89 0.012
peptidyl amino acid modification GO:0018193 58 0.012
regulation of programmed cell death GO:0043067 50 0.012
actin cytoskeleton organization GO:0030036 184 0.012
nucleotide catabolic process GO:0009166 77 0.012
fertilization GO:0009566 63 0.012
muscle cell differentiation GO:0042692 171 0.012
gene silencing by rna GO:0031047 143 0.012
phagocytosis GO:0006909 115 0.012
system process GO:0003008 136 0.011
organic cyclic compound catabolic process GO:1901361 119 0.011
regulation of multicellular organism growth GO:0040014 373 0.011
Worm
cellular amine metabolic process GO:0044106 15 0.011
cytokinetic process GO:0032506 10 0.011
negative regulation of developmental process GO:0051093 227 0.011
protein modification process GO:0036211 207 0.011
epithelial cell morphogenesis GO:0003382 2 0.011
regulation of cell development GO:0060284 49 0.011
developmental growth GO:0048589 412 0.011
Worm
signal transduction GO:0007165 317 0.011
positive regulation of growth GO:0045927 369 0.011
Worm
nucleobase containing compound catabolic process GO:0034655 114 0.011
amine metabolic process GO:0009308 15 0.011
single organism cellular localization GO:1902580 72 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.011
regulation of intracellular signal transduction GO:1902531 77 0.010
regulation of rna biosynthetic process GO:2001141 165 0.010
cellular response to abiotic stimulus GO:0071214 4 0.010
positive regulation of phosphate metabolic process GO:0045937 56 0.010
regulation of cellular protein metabolic process GO:0032268 75 0.010
regulation of rna metabolic process GO:0051252 173 0.010
myosin filament organization GO:0031033 138 0.010
positive regulation of rna biosynthetic process GO:1902680 102 0.010
microtubule anchoring GO:0034453 8 0.010

knl-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012