Caenorhabditis elegans

16 known processes

lig-1 (CELE_C29A12.3)

Protein LIG-1

lig-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of vulval development GO:0040028 248 0.750
negative regulation of vulval development GO:0040027 206 0.712
vulval development GO:0040025 333 0.483
embryo development GO:0009790 3052 0.317
post embryonic organ development GO:0048569 336 0.303
organ development GO:0048513 1102 0.287
cell development GO:0048468 696 0.230
transport GO:0006810 1093 0.221
regulation of nematode larval development GO:0061062 260 0.220
gene expression GO:0010467 412 0.220
nucleus organization GO:0006997 38 0.218
embryo development ending in birth or egg hatching GO:0009792 2992 0.199
post embryonic development GO:0009791 2152 0.193
sex differentiation GO:0007548 909 0.188
cell cycle GO:0007049 526 0.175
establishment of localization GO:0051234 1171 0.172
meiotic cell cycle process GO:1903046 170 0.171
regulation of post embryonic development GO:0048580 260 0.167
cell cycle process GO:0022402 482 0.166
meiotic cell cycle GO:0051321 335 0.166
cell fate commitment GO:0045165 139 0.153
protein complex biogenesis GO:0070271 186 0.151
regulation of developmental process GO:0050793 684 0.146
macromolecular complex subunit organization GO:0043933 320 0.144
macromolecule localization GO:0033036 771 0.142
protein complex subunit organization GO:0071822 280 0.139
meiotic nuclear division GO:0007126 300 0.118
generation of neurons GO:0048699 235 0.117
multicellular organismal reproductive process GO:0048609 815 0.117
single organism organelle organization GO:1902589 501 0.112
organelle organization GO:0006996 783 0.110
single organism reproductive process GO:0044702 1196 0.109
multi organism reproductive process GO:0044703 867 0.106
vesicle mediated transport GO:0016192 852 0.104
negative regulation of biological process GO:0048519 567 0.099
regulation of multicellular organismal development GO:2000026 317 0.097
macromolecular complex assembly GO:0065003 193 0.095
multicellular organism reproduction GO:0032504 819 0.094
negative regulation of nematode larval development GO:0061064 208 0.092
body morphogenesis GO:0010171 620 0.092
negative regulation of macromolecule metabolic process GO:0010605 229 0.091
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.090
negative regulation of post embryonic development GO:0048581 208 0.089
cellular nitrogen compound biosynthetic process GO:0044271 192 0.084
protein complex assembly GO:0006461 186 0.083
cellular component biogenesis GO:0044085 297 0.082
positive regulation of vulval development GO:0040026 52 0.080
negative regulation of developmental process GO:0051093 227 0.078
gonad development GO:0008406 840 0.077
cytoskeleton organization GO:0007010 339 0.077
oviposition GO:0018991 364 0.074
single organism localization GO:1902578 518 0.074
negative regulation of gene expression GO:0010629 217 0.073
regulation of biological quality GO:0065008 741 0.072
organelle assembly GO:0070925 214 0.070
death GO:0016265 547 0.069
rna biosynthetic process GO:0032774 169 0.069
cellular component assembly GO:0022607 293 0.068
aromatic compound biosynthetic process GO:0019438 192 0.067
mitotic cell cycle process GO:1903047 194 0.067
biosynthetic process GO:0009058 323 0.066
Mouse
maintenance of location GO:0051235 580 0.065
negative regulation of metabolic process GO:0009892 240 0.065
microtubule based process GO:0007017 182 0.062
regulation of multicellular organismal process GO:0051239 726 0.061
endocytosis GO:0006897 819 0.060
cell division GO:0051301 262 0.058
aging GO:0007568 812 0.057
anatomical structure formation involved in morphogenesis GO:0048646 250 0.055
negative regulation of multicellular organismal process GO:0051241 236 0.055
lipid storage GO:0019915 565 0.055
actin filament based process GO:0030029 191 0.054
determination of adult lifespan GO:0008340 812 0.053
lipid localization GO:0010876 573 0.053
regulation of macromolecule metabolic process GO:0060255 421 0.053
development of primary sexual characteristics GO:0045137 840 0.052
positive regulation of nematode larval development GO:0061063 54 0.051
dna duplex unwinding GO:0032508 3 0.051
apoptotic cell clearance GO:0043277 111 0.049
negative regulation of cellular process GO:0048523 239 0.049
negative regulation of gene expression epigenetic GO:0045814 2 0.049
neurogenesis GO:0022008 236 0.048
regulation of gene expression GO:0010468 366 0.048
neuron projection development GO:0031175 187 0.048
cell projection organization GO:0030030 231 0.047
gamete generation GO:0007276 461 0.047
receptor mediated endocytosis GO:0006898 715 0.045
nucleic acid metabolic process GO:0090304 299 0.045
Human Mouse
organic substance biosynthetic process GO:1901576 323 0.044
Mouse
multi multicellular organism process GO:0044706 390 0.044
multicellular organismal reproductive behavior GO:0033057 384 0.044
regulation of cell cycle GO:0051726 194 0.043
reproductive structure development GO:0048608 850 0.043
dna geometric change GO:0032392 3 0.042
germ cell development GO:0007281 351 0.042
small molecule metabolic process GO:0044281 186 0.041
multi organism reproductive behavior GO:0044705 387 0.041
meiotic chromosome segregation GO:0045132 139 0.041
reproductive system development GO:0061458 850 0.040
cellular localization GO:0051641 360 0.039
reproductive behavior GO:0019098 387 0.038
chromosome organization GO:0051276 104 0.038
axon development GO:0061564 163 0.038
tube morphogenesis GO:0035239 79 0.038
phagocytosis GO:0006909 115 0.037
neuron development GO:0048666 199 0.037
regulation of nucleic acid templated transcription GO:1903506 165 0.037
developmental process involved in reproduction GO:0003006 1165 0.036
g1 s transition of mitotic cell cycle GO:0000082 2 0.035
regulation of gene expression epigenetic GO:0040029 163 0.035
chromosome segregation GO:0007059 180 0.035
actin cytoskeleton organization GO:0030036 184 0.034
positive regulation of neurogenesis GO:0050769 4 0.034
membrane invagination GO:0010324 98 0.034
single organism transport GO:0044765 447 0.033
genitalia development GO:0048806 741 0.032
cell cycle phase transition GO:0044770 19 0.032
organelle fission GO:0048285 363 0.032
apoptotic process GO:0006915 478 0.031
chromatin modification GO:0016568 32 0.031
base excision repair GO:0006284 4 0.031
regulation of rna metabolic process GO:0051252 173 0.030
regulation of rna biosynthetic process GO:2001141 165 0.030
meiosis i GO:0007127 19 0.030
cellular protein complex assembly GO:0043623 178 0.029
membrane organization GO:0061024 135 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.029
multi organism behavior GO:0051705 389 0.029
female gamete generation GO:0007292 254 0.029
behavior GO:0007610 527 0.029
inductive cell migration GO:0040039 145 0.028
negative regulation of nucleic acid templated transcription GO:1903507 53 0.028
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.028
nervous system development GO:0007399 253 0.028
locomotion GO:0040011 1634 0.028
canonical wnt signaling pathway GO:0060070 3 0.028
phagocytosis engulfment GO:0006911 98 0.028
macromolecule biosynthetic process GO:0009059 250 0.027
Mouse
negative regulation of transcription dna templated GO:0045892 53 0.027
cell migration GO:0016477 306 0.026
negative regulation of cellular metabolic process GO:0031324 95 0.026
cellular component morphogenesis GO:0032989 318 0.026
regulation of cell cycle process GO:0010564 145 0.026
regulation of cellular component organization GO:0051128 248 0.025
muscle structure development GO:0061061 191 0.025
rna metabolic process GO:0016070 228 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.025
organonitrogen compound metabolic process GO:1901564 151 0.025
carbohydrate metabolic process GO:0005975 34 0.025
oogenesis GO:0048477 229 0.025
negative regulation of cell cycle g2 m phase transition GO:1902750 1 0.025
cellular ketone metabolic process GO:0042180 14 0.025
multicellular organism growth GO:0035264 385 0.024
neuron differentiation GO:0030182 217 0.024
regulation of primary metabolic process GO:0080090 292 0.024
cellular macromolecular complex assembly GO:0034622 184 0.024
regulation of mitotic cell cycle GO:0007346 76 0.024
establishment of localization in cell GO:0051649 318 0.024
regulation of organelle organization GO:0033043 164 0.023
covalent chromatin modification GO:0016569 30 0.023
protein metabolic process GO:0019538 422 0.023
negative regulation of biosynthetic process GO:0009890 65 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.023
engulfment of apoptotic cell GO:0043652 94 0.022
rna interference GO:0016246 137 0.022
negative regulation of cell cycle GO:0045786 53 0.022
cellular component assembly involved in morphogenesis GO:0010927 183 0.022
striated muscle myosin thick filament assembly GO:0071688 138 0.022
posttranscriptional regulation of gene expression GO:0010608 166 0.022
sexual reproduction GO:0019953 546 0.022
purine ribonucleoside metabolic process GO:0046128 92 0.022
nucleobase containing compound metabolic process GO:0006139 406 0.022
Human Mouse
myosin filament organization GO:0031033 138 0.021
localization of cell GO:0051674 313 0.021
negative regulation of cellular biosynthetic process GO:0031327 65 0.021
positive regulation of developmental growth GO:0048639 354 0.021
sensory organ morphogenesis GO:0090596 2 0.021
developmental growth GO:0048589 412 0.021
regulation of cellular metabolic process GO:0031323 305 0.021
single organism catabolic process GO:0044712 129 0.021
macromolecule modification GO:0043412 218 0.021
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.020
heterocycle biosynthetic process GO:0018130 187 0.020
negative regulation of rna biosynthetic process GO:1902679 53 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.020
cell cycle g1 s phase transition GO:0044843 2 0.020
myosin filament assembly GO:0031034 138 0.020
nucleobase containing compound biosynthetic process GO:0034654 184 0.020
transcription dna templated GO:0006351 168 0.020
signal transduction GO:0007165 317 0.020
kinetochore assembly GO:0051382 5 0.020
positive regulation of multicellular organismal process GO:0051240 417 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.020
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.019
regulation of multicellular organism growth GO:0040014 373 0.019
small gtpase mediated signal transduction GO:0007264 32 0.019
internal peptidyl lysine acetylation GO:0018393 3 0.019
digestive tract morphogenesis GO:0048546 76 0.019
cellular biosynthetic process GO:0044249 315 0.019
Mouse
response to chemical GO:0042221 356 0.019
Mouse
positive regulation of rna biosynthetic process GO:1902680 102 0.019
hermaphrodite genitalia development GO:0040035 734 0.019
positive regulation of cellular process GO:0048522 332 0.018
multicellular organismal aging GO:0010259 812 0.018
growth GO:0040007 562 0.018
striated muscle cell development GO:0055002 157 0.018
transcription from rna polymerase ii promoter GO:0006366 149 0.018
centriole assembly GO:0098534 5 0.018
dna metabolic process GO:0006259 74 0.018
Human Mouse
establishment of nucleus localization GO:0040023 55 0.018
head development GO:0060322 1 0.018
regulation of transcription dna templated GO:0006355 164 0.017
oxoacid metabolic process GO:0043436 47 0.017
positive regulation of developmental process GO:0051094 408 0.017
muscle cell differentiation GO:0042692 171 0.017
muscle cell development GO:0055001 158 0.017
regulation of nucleocytoplasmic transport GO:0046822 3 0.017
phosphate containing compound metabolic process GO:0006796 232 0.017
mitotic spindle organization GO:0007052 81 0.017
protein modification process GO:0036211 207 0.017
tissue development GO:0009888 112 0.017
dna replication checkpoint GO:0000076 1 0.017
posttranscriptional gene silencing by rna GO:0035194 143 0.017
cellular macromolecule biosynthetic process GO:0034645 247 0.017
Mouse
regulation of cell cycle phase transition GO:1901987 13 0.017
protein oligomerization GO:0051259 4 0.016
posttranscriptional gene silencing GO:0016441 143 0.016
programmed cell death GO:0012501 500 0.016
regulation of developmental growth GO:0048638 389 0.016
actomyosin structure organization GO:0031032 154 0.016
positive regulation of growth GO:0045927 369 0.016
striated muscle cell differentiation GO:0051146 158 0.016
cellular response to chemical stimulus GO:0070887 129 0.016
single organism signaling GO:0044700 401 0.016
cell death GO:0008219 547 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
intracellular transport GO:0046907 77 0.016
cellular nitrogen compound catabolic process GO:0044270 119 0.016
nuclear pore organization GO:0006999 2 0.016
regulation of cellular biosynthetic process GO:0031326 189 0.016
signaling GO:0023052 401 0.016
amine metabolic process GO:0009308 15 0.015
regulation of biosynthetic process GO:0009889 189 0.015
regulation of protein metabolic process GO:0051246 81 0.015
chromatin remodeling GO:0006338 2 0.015
cell cycle g2 m phase transition GO:0044839 1 0.015
regulation of neuron differentiation GO:0045664 40 0.015
purine nucleoside monophosphate metabolic process GO:0009126 43 0.015
cellular amine metabolic process GO:0044106 15 0.014
histone modification GO:0016570 30 0.014
axonal fasciculation GO:0007413 79 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 5 0.014
somatic muscle development GO:0007525 1 0.014
actin filament based movement GO:0030048 4 0.014
peptidyl lysine acetylation GO:0018394 3 0.014
negative regulation of neurogenesis GO:0050768 4 0.014
positive regulation of chromosome organization GO:2001252 2 0.014
gene silencing GO:0016458 143 0.013
organic substance catabolic process GO:1901575 294 0.013
regulation of macromolecule biosynthetic process GO:0010556 189 0.013
organic cyclic compound biosynthetic process GO:1901362 195 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
cytokinesis GO:0000910 80 0.013
cellular catabolic process GO:0044248 199 0.013
neuron recognition GO:0008038 83 0.013
positive regulation of embryonic development GO:0040019 3 0.013
protein localization GO:0008104 205 0.013
myofibril assembly GO:0030239 154 0.013
ribonucleotide metabolic process GO:0009259 99 0.013
carboxylic acid metabolic process GO:0019752 34 0.013
gastrulation GO:0007369 58 0.013
digestive system development GO:0055123 122 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.013
cell type specific apoptotic process GO:0097285 4 0.013
reciprocal meiotic recombination GO:0007131 11 0.013
ribonucleoside monophosphate metabolic process GO:0009161 45 0.013
cellular protein metabolic process GO:0044267 279 0.013
hatching GO:0035188 48 0.013
gene silencing by rna GO:0031047 143 0.013
regulation of epithelial cell differentiation GO:0030856 4 0.012
negative regulation of rna metabolic process GO:0051253 53 0.012
purine nucleoside catabolic process GO:0006152 75 0.012
response to oxygen containing compound GO:1901700 44 0.012
Mouse
meiosis ii GO:0007135 16 0.012
spindle organization GO:0007051 92 0.012
regulation of growth GO:0040008 409 0.012
positive regulation of multicellular organism growth GO:0040018 352 0.012
negative regulation of cell cycle process GO:0010948 12 0.012
oocyte construction GO:0007308 2 0.012
neuromuscular junction development GO:0007528 2 0.012
organelle localization GO:0051640 127 0.012
regulation of metabolic process GO:0019222 478 0.012
regulation of g1 s transition of mitotic cell cycle GO:2000045 1 0.012
mitotic spindle stabilization GO:0043148 2 0.012
positive regulation of intracellular transport GO:0032388 2 0.012
cellular response to abiotic stimulus GO:0071214 4 0.012
regulation of response to stimulus GO:0048583 243 0.012
single organism biosynthetic process GO:0044711 91 0.011
internal protein amino acid acetylation GO:0006475 3 0.011
male anatomical structure morphogenesis GO:0090598 78 0.011
centromere complex assembly GO:0034508 5 0.011
positive regulation of cellular biosynthetic process GO:0031328 109 0.011
mitotic g2 m transition checkpoint GO:0044818 1 0.011
purine ribonucleotide metabolic process GO:0009150 95 0.011
catabolic process GO:0009056 318 0.011
aromatic compound catabolic process GO:0019439 116 0.011
positive regulation of nucleic acid templated transcription GO:1903508 102 0.011
intracellular signal transduction GO:0035556 96 0.011
positive regulation of epithelial cell proliferation GO:0050679 1 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.011
cell recognition GO:0008037 85 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.010
regulation of protein stability GO:0031647 3 0.010
proximal distal pattern formation GO:0009954 6 0.010
cellular response to organic substance GO:0071310 119 0.010
response to wounding GO:0009611 4 0.010
nematode male tail tip morphogenesis GO:0045138 77 0.010
dna topological change GO:0006265 1 0.010
cell cell signaling GO:0007267 118 0.010
regulation of cell cycle g1 s phase transition GO:1902806 1 0.010
regulation of nitrogen compound metabolic process GO:0051171 222 0.010
axonogenesis GO:0007409 102 0.010
mitotic cell cycle phase transition GO:0044772 13 0.010
positive regulation of chromosome segregation GO:0051984 1 0.010
cell substrate adhesion GO:0031589 1 0.010

lig-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
cancer DOID:162 0 0.023
disease of cellular proliferation DOID:14566 0 0.023
organ system cancer DOID:0050686 0 0.023
gastrointestinal system cancer DOID:3119 0 0.019
large intestine cancer DOID:5672 0 0.013
intestinal cancer DOID:10155 0 0.013
nervous system disease DOID:863 0 0.013