Caenorhabditis elegans

46 known processes

pbo-4 (CELE_K09C8.1)

Protein PBO-4

pbo-4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.449
Worm
embryo development GO:0009790 3052 0.359
Mouse Worm
multicellular organism reproduction GO:0032504 819 0.355
developmental process involved in reproduction GO:0003006 1165 0.323
single organism reproductive process GO:0044702 1196 0.318
post embryonic development GO:0009791 2152 0.290
Worm
organ development GO:0048513 1102 0.263
Mouse
monovalent inorganic cation homeostasis GO:0055067 6 0.245
locomotion GO:0040011 1634 0.229
Worm
gamete generation GO:0007276 461 0.223
response to external stimulus GO:0009605 289 0.220
nervous system development GO:0007399 253 0.212
multicellular organismal reproductive process GO:0048609 815 0.202
multicellular organismal aging GO:0010259 812 0.199
Worm
regulation of developmental growth GO:0048638 389 0.196
Worm
sexual reproduction GO:0019953 546 0.188
macromolecule localization GO:0033036 771 0.181
Mouse Worm
reproductive system development GO:0061458 850 0.179
sex differentiation GO:0007548 909 0.164
aging GO:0007568 812 0.163
Worm
organelle organization GO:0006996 783 0.161
mitotic nuclear division GO:0007067 89 0.154
innate immune response GO:0045087 190 0.147
positive regulation of multicellular organismal process GO:0051240 417 0.145
multi organism reproductive process GO:0044703 867 0.142
response to other organism GO:0051707 101 0.141
growth GO:0040007 562 0.141
germ cell development GO:0007281 351 0.140
gonad development GO:0008406 840 0.138
establishment of localization in cell GO:0051649 318 0.133
establishment of localization GO:0051234 1171 0.130
Human Zebrafish Mouse Worm
behavior GO:0007610 527 0.123
Worm
single organism signaling GO:0044700 401 0.119
development of primary sexual characteristics GO:0045137 840 0.117
transport GO:0006810 1093 0.115
Human Zebrafish Mouse Worm
multicellular organismal reproductive behavior GO:0033057 384 0.113
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.110
regulation of biological quality GO:0065008 741 0.106
positive regulation of developmental process GO:0051094 408 0.103
Worm
multicellular organism growth GO:0035264 385 0.103
Worm
regulation of signaling GO:0023051 172 0.099
regulation of cell communication GO:0010646 176 0.094
cellular component movement GO:0006928 388 0.092
hermaphrodite genitalia development GO:0040035 734 0.092
regulation of multicellular organismal process GO:0051239 726 0.089
digestive tract morphogenesis GO:0048546 76 0.087
multi multicellular organism process GO:0044706 390 0.085
positive regulation of developmental growth GO:0048639 354 0.085
Worm
single organism organelle organization GO:1902589 501 0.083
multi organism reproductive behavior GO:0044705 387 0.083
cell development GO:0048468 696 0.080
Mouse
negative regulation of macromolecule metabolic process GO:0010605 229 0.079
organic substance catabolic process GO:1901575 294 0.079
reproductive structure development GO:0048608 850 0.079
neurogenesis GO:0022008 236 0.078
response to biotic stimulus GO:0009607 101 0.078
negative regulation of biological process GO:0048519 567 0.078
positive regulation of biosynthetic process GO:0009891 109 0.076
positive regulation of growth GO:0045927 369 0.076
Worm
developmental growth GO:0048589 412 0.075
Worm
maintenance of location GO:0051235 580 0.075
Worm
positive regulation of multicellular organism growth GO:0040018 352 0.072
Worm
receptor mediated endocytosis GO:0006898 715 0.071
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.071
lipid storage GO:0019915 565 0.070
Worm
genitalia development GO:0048806 741 0.070
protein metabolic process GO:0019538 422 0.069
signaling GO:0023052 401 0.067
oviposition GO:0018991 364 0.064
single organism transport GO:0044765 447 0.064
Human Zebrafish Mouse Worm
lipid localization GO:0010876 573 0.063
Worm
digestive tract development GO:0048565 122 0.062
single organism behavior GO:0044708 83 0.061
sodium ion transmembrane transport GO:0035725 8 0.061
Human Zebrafish Mouse Worm
cell migration GO:0016477 306 0.060
regulation of developmental process GO:0050793 684 0.058
Worm
defense response to other organism GO:0098542 100 0.058
localization of cell GO:0051674 313 0.058
cell fate commitment GO:0045165 139 0.057
cell cell signaling GO:0007267 118 0.057
regulation of multicellular organism growth GO:0040014 373 0.057
Worm
cell division GO:0051301 262 0.054
chromosome organization GO:0051276 104 0.053
tube development GO:0035295 126 0.053
cellular protein metabolic process GO:0044267 279 0.051
regulation of growth GO:0040008 409 0.051
Worm
cellular response to stress GO:0033554 162 0.051
oogenesis GO:0048477 229 0.050
single organism localization GO:1902578 518 0.050
Human Zebrafish Mouse Worm
defense response GO:0006952 296 0.050
organonitrogen compound metabolic process GO:1901564 151 0.049
cell cycle GO:0007049 526 0.048
reproductive behavior GO:0019098 387 0.047
organic substance transport GO:0071702 113 0.046
Worm
regulation of primary metabolic process GO:0080090 292 0.046
phosphorus metabolic process GO:0006793 232 0.046
generation of neurons GO:0048699 235 0.045
cell morphogenesis GO:0000902 163 0.044
intracellular transport GO:0046907 77 0.044
neuron differentiation GO:0030182 217 0.043
cell surface receptor signaling pathway GO:0007166 149 0.043
organic substance biosynthetic process GO:1901576 323 0.042
female gamete generation GO:0007292 254 0.042
synaptic transmission GO:0007268 106 0.042
cellular component morphogenesis GO:0032989 318 0.042
response to external biotic stimulus GO:0043207 101 0.041
negative regulation of metabolic process GO:0009892 240 0.041
cell death GO:0008219 547 0.041
endocytosis GO:0006897 819 0.041
gene expression GO:0010467 412 0.040
response to organic substance GO:0010033 131 0.040
cellular component biogenesis GO:0044085 297 0.040
negative regulation of gene expression GO:0010629 217 0.039
regulation of protein metabolic process GO:0051246 81 0.039
multi organism behavior GO:0051705 389 0.038
meiotic cell cycle GO:0051321 335 0.038
cell motility GO:0048870 313 0.038
cellular component assembly GO:0022607 293 0.038
single organism intracellular transport GO:1902582 70 0.037
death GO:0016265 547 0.037
body morphogenesis GO:0010171 620 0.037
Worm
chromosome segregation GO:0007059 180 0.036
regulation of cellular metabolic process GO:0031323 305 0.036
catabolic process GO:0009056 318 0.036
determination of adult lifespan GO:0008340 812 0.035
Worm
regulation of multicellular organismal development GO:2000026 317 0.034
apoptotic process GO:0006915 478 0.034
digestive system development GO:0055123 122 0.034
response to wounding GO:0009611 4 0.034
signal transduction GO:0007165 317 0.033
programmed cell death GO:0012501 500 0.033
ion transmembrane transport GO:0034220 91 0.033
Human Zebrafish Mouse Worm
ion transport GO:0006811 113 0.033
Human Zebrafish Mouse Worm
mitotic cell cycle process GO:1903047 194 0.032
positive regulation of cellular process GO:0048522 332 0.032
vesicle mediated transport GO:0016192 852 0.031
protein modification process GO:0036211 207 0.031
biosynthetic process GO:0009058 323 0.030
negative regulation of response to stimulus GO:0048585 73 0.030
meiotic nuclear division GO:0007126 300 0.030
regulation of signal transduction GO:0009966 135 0.030
regulation of organelle organization GO:0033043 164 0.029
chromatin modification GO:0016568 32 0.029
regulation of behavior GO:0050795 97 0.029
Worm
macromolecular complex subunit organization GO:0043933 320 0.029
negative regulation of multicellular organismal process GO:0051241 236 0.029
phosphorylation GO:0016310 116 0.029
cytoskeleton organization GO:0007010 339 0.029
negative regulation of cellular component organization GO:0051129 33 0.028
response to chemical GO:0042221 356 0.028
defense response to bacterium GO:0042742 86 0.026
neuron projection development GO:0031175 187 0.026
regulation of apoptotic signaling pathway GO:2001233 1 0.026
regulation of macromolecule metabolic process GO:0060255 421 0.026
regulation of nitrogen compound metabolic process GO:0051171 222 0.026
skeletal muscle organ development GO:0060538 3 0.026
regulation of gene expression epigenetic GO:0040029 163 0.025
lipid metabolic process GO:0006629 77 0.025
cellular response to organic substance GO:0071310 119 0.025
cation transport GO:0006812 78 0.025
Human Zebrafish Mouse Worm
intracellular signal transduction GO:0035556 96 0.025
organelle fission GO:0048285 363 0.025
defense response to gram negative bacterium GO:0050829 64 0.025
organ morphogenesis GO:0009887 67 0.025
actomyosin structure organization GO:0031032 154 0.024
system process GO:0003008 136 0.024
macromolecule modification GO:0043412 218 0.024
negative regulation of cell cycle GO:0045786 53 0.024
ion homeostasis GO:0050801 21 0.024
regulation of biosynthetic process GO:0009889 189 0.024
positive regulation of signaling GO:0023056 66 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.024
regulation of transport GO:0051049 91 0.023
Worm
phosphate containing compound metabolic process GO:0006796 232 0.023
feeding behavior GO:0007631 70 0.023
Worm
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.022
transmembrane transport GO:0055085 110 0.022
Human Zebrafish Mouse Worm
protein complex biogenesis GO:0070271 186 0.022
cell cycle process GO:0022402 482 0.022
regulation of cellular component organization GO:0051128 248 0.022
regulation of lipid biosynthetic process GO:0046890 1 0.022
regulation of metabolic process GO:0019222 478 0.022
regulation of gene expression GO:0010468 366 0.021
posttranscriptional regulation of gene expression GO:0010608 166 0.021
cell proliferation GO:0008283 116 0.021
negative regulation of gene expression epigenetic GO:0045814 2 0.021
muscle organ development GO:0007517 26 0.021
immune response GO:0006955 192 0.020
response to topologically incorrect protein GO:0035966 82 0.020
membrane organization GO:0061024 135 0.020
cellular response to abiotic stimulus GO:0071214 4 0.020
cellular protein complex assembly GO:0043623 178 0.020
organic cyclic compound catabolic process GO:1901361 119 0.020
regulation of mitotic cell cycle GO:0007346 76 0.020
single organism biosynthetic process GO:0044711 91 0.020
nuclear envelope reassembly GO:0031468 4 0.020
inactivation of mapkkk activity GO:0051390 2 0.019
negative regulation of neurogenesis GO:0050768 4 0.019
regulation of cellular localization GO:0060341 42 0.019
taxis GO:0042330 128 0.019
nucleobase containing compound metabolic process GO:0006139 406 0.019
negative regulation of signal transduction GO:0009968 60 0.018
positive regulation of metabolic process GO:0009893 187 0.018
cation homeostasis GO:0055080 20 0.018
regulation of locomotion GO:0040012 161 0.018
adult behavior GO:0030534 3 0.018
actin cytoskeleton organization GO:0030036 184 0.018
small molecule metabolic process GO:0044281 186 0.018
anatomical structure formation involved in morphogenesis GO:0048646 250 0.018
response to bacterium GO:0009617 86 0.018
chromatin organization GO:0006325 32 0.018
meiotic cell cycle process GO:1903046 170 0.017
cellular biosynthetic process GO:0044249 315 0.017
cellular localization GO:0051641 360 0.017
learning or memory GO:0007611 27 0.017
negative regulation of cell communication GO:0010648 61 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.017
nucleus organization GO:0006997 38 0.017
transcription from rna polymerase ii promoter GO:0006366 149 0.017
positive regulation of cell communication GO:0010647 69 0.017
neurological system process GO:0050877 53 0.017
organelle assembly GO:0070925 214 0.016
aromatic compound catabolic process GO:0019439 116 0.016
striated muscle cell differentiation GO:0051146 158 0.016
Mouse
cellular amine metabolic process GO:0044106 15 0.016
regulation of cell cycle GO:0051726 194 0.016
macromolecular complex assembly GO:0065003 193 0.016
positive regulation of molecular function GO:0044093 61 0.016
actin filament based process GO:0030029 191 0.016
tissue development GO:0009888 112 0.016
Mouse
negative regulation of signaling GO:0023057 61 0.016
enzyme linked receptor protein signaling pathway GO:0007167 50 0.016
cellular macromolecular complex assembly GO:0034622 184 0.016
protein localization GO:0008104 205 0.016
Mouse
myosin filament assembly GO:0031034 138 0.016
regulation of cellular component movement GO:0051270 62 0.015
positive regulation of nucleic acid templated transcription GO:1903508 102 0.015
protein complex assembly GO:0006461 186 0.015
positive regulation of cellular metabolic process GO:0031325 178 0.015
heterocycle biosynthetic process GO:0018130 187 0.015
muscle structure development GO:0061061 191 0.015
Mouse
cell projection morphogenesis GO:0048858 148 0.015
cellular response to chemical stimulus GO:0070887 129 0.015
response to abiotic stimulus GO:0009628 152 0.015
Human Zebrafish Mouse
regulation of intracellular signal transduction GO:1902531 77 0.015
amine metabolic process GO:0009308 15 0.015
negative regulation of cellular metabolic process GO:0031324 95 0.015
microtubule based process GO:0007017 182 0.015
gastrulation GO:0007369 58 0.015
cellular catabolic process GO:0044248 199 0.015
epithelial cell proliferation GO:0050673 1 0.014
cellular protein localization GO:0034613 75 0.014
muscle tissue development GO:0060537 1 0.014
Mouse
macromolecule catabolic process GO:0009057 202 0.014
sodium ion transport GO:0006814 10 0.014
Human Zebrafish Mouse Worm
rna biosynthetic process GO:0032774 169 0.014
heterocycle catabolic process GO:0046700 119 0.014
posttranscriptional gene silencing by rna GO:0035194 143 0.014
negative regulation of cellular process GO:0048523 239 0.014
protein complex subunit organization GO:0071822 280 0.014
muscle cell differentiation GO:0042692 171 0.014
Mouse
striated muscle myosin thick filament assembly GO:0071688 138 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.014
regulation of cellular protein metabolic process GO:0032268 75 0.014
cellular homeostasis GO:0019725 22 0.014
negative regulation of rna biosynthetic process GO:1902679 53 0.014
tissue morphogenesis GO:0048729 65 0.013
negative regulation of developmental process GO:0051093 227 0.013
protein catabolic process GO:0030163 162 0.013
posttranscriptional gene silencing GO:0016441 143 0.013
gene silencing GO:0016458 143 0.013
er nucleus signaling pathway GO:0006984 66 0.013
regulation of post embryonic development GO:0048580 260 0.013
negative regulation of post embryonic development GO:0048581 208 0.013
regulation of cellular ph GO:0030641 4 0.013
cell projection organization GO:0030030 231 0.013
cytoplasmic transport GO:0016482 23 0.012
single organism catabolic process GO:0044712 129 0.012
cellular protein modification process GO:0006464 207 0.012
mitotic nuclear envelope reassembly GO:0007084 3 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.012
regulation of lipid metabolic process GO:0019216 4 0.012
muscle organ morphogenesis GO:0048644 4 0.012
positive regulation of protein metabolic process GO:0051247 45 0.012
homeostatic process GO:0042592 51 0.012
male mating behavior GO:0060179 26 0.012
positive regulation of rna metabolic process GO:0051254 103 0.012
positive regulation of cellular biosynthetic process GO:0031328 109 0.012
regulation of protein kinase activity GO:0045859 28 0.012
positive regulation of macromolecule metabolic process GO:0010604 149 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
collagen and cuticulin based cuticle development GO:0040002 99 0.012
neuron development GO:0048666 199 0.012
regulation of cytoskeleton organization GO:0051493 41 0.012
cuticle development GO:0042335 100 0.012
regulation of localization GO:0032879 194 0.011
Worm
head development GO:0060322 1 0.011
myosin filament organization GO:0031033 138 0.011
cellular nitrogen compound catabolic process GO:0044270 119 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
sensory organ morphogenesis GO:0090596 2 0.011
adult locomotory behavior GO:0008344 1 0.011
intraspecies interaction between organisms GO:0051703 3 0.011
secretion by cell GO:0032940 138 0.011
regulation of cellular biosynthetic process GO:0031326 189 0.011
regulation of programmed cell death GO:0043067 50 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
nucleic acid templated transcription GO:0097659 169 0.011
hormone transport GO:0009914 2 0.010
protein oligomerization GO:0051259 4 0.010
cation transmembrane transport GO:0098655 59 0.010
Human Zebrafish Mouse Worm
regulation of ph GO:0006885 6 0.010
regulation of nematode larval development GO:0061062 260 0.010
negative regulation of cellular biosynthetic process GO:0031327 65 0.010
protein modification by small protein conjugation or removal GO:0070647 40 0.010
internal peptidyl lysine acetylation GO:0018393 3 0.010
cellular protein complex localization GO:0034629 3 0.010
peptidyl lysine acetylation GO:0018394 3 0.010
organelle localization GO:0051640 127 0.010

pbo-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.014
congenital muscular dystrophy DOID:0050557 0 0.014
muscular disease DOID:0080000 0 0.014
muscular dystrophy DOID:9884 0 0.014
disease of anatomical entity DOID:7 0 0.014
musculoskeletal system disease DOID:17 0 0.014
muscle tissue disease DOID:66 0 0.014