Caenorhabditis elegans

65 known processes

smc-3 (CELE_Y47D3A.26)

Protein SMC-3

smc-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hermaphrodite genitalia development GO:0040035 734 0.857
reproductive system development GO:0061458 850 0.824
embryo development ending in birth or egg hatching GO:0009792 2992 0.809
gene expression GO:0010467 412 0.781
regulation of vulval development GO:0040028 248 0.677
nucleobase containing compound metabolic process GO:0006139 406 0.647
rna metabolic process GO:0016070 228 0.638
organ development GO:0048513 1102 0.631
genitalia development GO:0048806 741 0.620
cellular nitrogen compound biosynthetic process GO:0044271 192 0.612
post embryonic organ development GO:0048569 336 0.589
embryo development GO:0009790 3052 0.581
mitotic sister chromatid segregation GO:0000070 38 0.580
Yeast Zebrafish
cell cycle process GO:0022402 482 0.540
post embryonic development GO:0009791 2152 0.539
developmental process involved in reproduction GO:0003006 1165 0.520
gonad development GO:0008406 840 0.519
development of primary sexual characteristics GO:0045137 840 0.518
mitotic cell cycle process GO:1903047 194 0.488
Human Yeast Zebrafish
negative regulation of vulval development GO:0040027 206 0.487
negative regulation of biological process GO:0048519 567 0.484
Human
sex differentiation GO:0007548 909 0.476
single organism reproductive process GO:0044702 1196 0.470
regulation of cell cycle process GO:0010564 145 0.455
Human
vulval development GO:0040025 333 0.452
transcription dna templated GO:0006351 168 0.426
regulation of meiotic cell cycle GO:0051445 136 0.381
reproductive structure development GO:0048608 850 0.367
regulation of gene expression GO:0010468 366 0.360
single organism organelle organization GO:1902589 501 0.359
regulation of transcription dna templated GO:0006355 164 0.351
chromosome organization GO:0051276 104 0.350
rrna metabolic process GO:0016072 3 0.344
regulation of nematode larval development GO:0061062 260 0.341
organic substance biosynthetic process GO:1901576 323 0.336
Human
sister chromatid segregation GO:0000819 46 0.336
Yeast Zebrafish
mitotic nuclear division GO:0007067 89 0.316
Yeast Zebrafish
regulation of metabolic process GO:0019222 478 0.311
Human
nucleic acid templated transcription GO:0097659 169 0.302
cellular macromolecule biosynthetic process GO:0034645 247 0.285
Human
regulation of biosynthetic process GO:0009889 189 0.280
Human
protein complex subunit organization GO:0071822 280 0.273
Human
organic cyclic compound biosynthetic process GO:1901362 195 0.260
locomotion GO:0040011 1634 0.253
nucleobase containing compound biosynthetic process GO:0034654 184 0.250
heterocycle biosynthetic process GO:0018130 187 0.248
regulation of mitotic cell cycle GO:0007346 76 0.245
establishment of localization GO:0051234 1171 0.245
cellular catabolic process GO:0044248 199 0.241
regulation of nuclear division GO:0051783 115 0.241
negative regulation of gene expression GO:0010629 217 0.229
cell cycle GO:0007049 526 0.227
nucleic acid metabolic process GO:0090304 299 0.219
apoptotic process GO:0006915 478 0.198
regulation of cellular component organization GO:0051128 248 0.194
regulation of cell cycle GO:0051726 194 0.191
Human
protein modification process GO:0036211 207 0.185
regulation of rna biosynthetic process GO:2001141 165 0.183
multicellular organism reproduction GO:0032504 819 0.181
regulation of organelle organization GO:0033043 164 0.177
regulation of post embryonic development GO:0048580 260 0.163
body morphogenesis GO:0010171 620 0.162
transcription from rna polymerase ii promoter GO:0006366 149 0.161
regulation of nucleic acid templated transcription GO:1903506 165 0.161
chromosome segregation GO:0007059 180 0.159
organelle organization GO:0006996 783 0.159
regulation of macromolecule metabolic process GO:0060255 421 0.157
Human
cellular biosynthetic process GO:0044249 315 0.157
Human
multicellular organismal reproductive process GO:0048609 815 0.157
negative regulation of nematode larval development GO:0061064 208 0.156
regulation of mitosis GO:0007088 18 0.155
meiotic cell cycle GO:0051321 335 0.151
Human Yeast
aromatic compound biosynthetic process GO:0019438 192 0.150
rna biosynthetic process GO:0032774 169 0.149
meiotic nuclear division GO:0007126 300 0.148
Human Yeast
negative regulation of post embryonic development GO:0048581 208 0.145
regulation of gene expression epigenetic GO:0040029 163 0.142
cellular protein modification process GO:0006464 207 0.140
regulation of cell division GO:0051302 142 0.137
macromolecular complex assembly GO:0065003 193 0.136
receptor mediated endocytosis GO:0006898 715 0.136
microtubule cytoskeleton organization involved in mitosis GO:1902850 12 0.135
catabolic process GO:0009056 318 0.130
regulation of developmental process GO:0050793 684 0.129
ribonucleoprotein complex assembly GO:0022618 4 0.127
cellular protein metabolic process GO:0044267 279 0.124
single organism localization GO:1902578 518 0.124
negative regulation of metabolic process GO:0009892 240 0.123
Human
regulation of meiosis GO:0040020 94 0.123
negative regulation of macromolecule metabolic process GO:0010605 229 0.121
Human
positive regulation of nematode larval development GO:0061063 54 0.117
macromolecular complex subunit organization GO:0043933 320 0.115
Human
ribosome biogenesis GO:0042254 4 0.114
meiotic cell cycle process GO:1903046 170 0.112
Yeast
dna metabolic process GO:0006259 74 0.109
regulation of chromosome organization GO:0033044 20 0.107
regulation of rna metabolic process GO:0051252 173 0.106
positive regulation of vulval development GO:0040026 52 0.104
gamete generation GO:0007276 461 0.101
microtubule based process GO:0007017 182 0.101
Human
endocytosis GO:0006897 819 0.098
protein complex assembly GO:0006461 186 0.097
nucleus organization GO:0006997 38 0.096
biosynthetic process GO:0009058 323 0.096
Human
oviposition GO:0018991 364 0.095
macromolecule biosynthetic process GO:0009059 250 0.090
Human
inductive cell migration GO:0040039 145 0.090
multicellular organismal reproductive behavior GO:0033057 384 0.088
gene silencing GO:0016458 143 0.088
cytoskeleton organization GO:0007010 339 0.087
Human
cellular component biogenesis GO:0044085 297 0.087
Yeast
transport GO:0006810 1093 0.085
regulation of multicellular organismal process GO:0051239 726 0.082
multi organism reproductive process GO:0044703 867 0.080
Yeast
macromolecule catabolic process GO:0009057 202 0.079
positive regulation of rna biosynthetic process GO:1902680 102 0.074
macromolecule localization GO:0033036 771 0.073
cellular macromolecular complex assembly GO:0034622 184 0.073
cell migration GO:0016477 306 0.070
protein complex biogenesis GO:0070271 186 0.070
cell development GO:0048468 696 0.068
Yeast
positive regulation of transcription dna templated GO:0045893 102 0.068
posttranscriptional gene silencing GO:0016441 143 0.068
positive regulation of cellular process GO:0048522 332 0.068
vesicle mediated transport GO:0016192 852 0.066
positive regulation of gene expression GO:0010628 112 0.066
histone modification GO:0016570 30 0.066
nervous system development GO:0007399 253 0.066
negative regulation of cellular process GO:0048523 239 0.065
Human
regulation of biological quality GO:0065008 741 0.065
organic substance catabolic process GO:1901575 294 0.064
positive regulation of growth GO:0045927 369 0.063
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.062
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.062
spindle organization GO:0007051 92 0.062
Human
cell motility GO:0048870 313 0.062
rrna processing GO:0006364 3 0.061
maintenance of location GO:0051235 580 0.060
nucleobase containing compound catabolic process GO:0034655 114 0.060
cell division GO:0051301 262 0.060
negative regulation of cellular biosynthetic process GO:0031327 65 0.059
Human
establishment of organelle localization GO:0051656 123 0.059
signal transduction GO:0007165 317 0.058
Human
single organism cellular localization GO:1902580 72 0.058
regulation of cellular metabolic process GO:0031323 305 0.058
Human
lipid storage GO:0019915 565 0.058
rna processing GO:0006396 34 0.056
regulation of multicellular organismal development GO:2000026 317 0.056
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.056
macromolecule modification GO:0043412 218 0.055
protein metabolic process GO:0019538 422 0.055
maintenance of protein location in cell GO:0032507 12 0.055
proteolysis GO:0006508 61 0.054
posttranscriptional gene silencing by rna GO:0035194 143 0.053
positive regulation of multicellular organismal process GO:0051240 417 0.053
signaling GO:0023052 401 0.053
Human
sexual reproduction GO:0019953 546 0.053
Yeast
organelle localization GO:0051640 127 0.053
regulation of multicellular organism growth GO:0040014 373 0.052
reproductive behavior GO:0019098 387 0.052
mrna metabolic process GO:0016071 31 0.051
developmental growth GO:0048589 412 0.051
negative regulation of cell cycle GO:0045786 53 0.050
Human
lipid localization GO:0010876 573 0.050
multicellular organismal aging GO:0010259 812 0.049
establishment of localization in cell GO:0051649 318 0.049
dna conformation change GO:0071103 11 0.048
regulation of developmental growth GO:0048638 389 0.046
cellular macromolecule catabolic process GO:0044265 73 0.045
digestive tract development GO:0048565 122 0.045
cell cycle phase transition GO:0044770 19 0.044
regulation of nitrogen compound metabolic process GO:0051171 222 0.044
Human
neurogenesis GO:0022008 236 0.044
rna interference GO:0016246 137 0.044
cellular localization GO:0051641 360 0.044
negative regulation of cellular metabolic process GO:0031324 95 0.044
Human
positive regulation of developmental process GO:0051094 408 0.044
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.043
positive regulation of multicellular organism growth GO:0040018 352 0.043
programmed cell death GO:0012501 500 0.043
mitotic cell cycle phase transition GO:0044772 13 0.042
organelle assembly GO:0070925 214 0.042
single organism transport GO:0044765 447 0.042
cellular component assembly GO:0022607 293 0.042
Yeast
negative regulation of transcription dna templated GO:0045892 53 0.042
negative regulation of nucleic acid templated transcription GO:1903507 53 0.040
cellular response to abiotic stimulus GO:0071214 4 0.040
regulation of growth GO:0040008 409 0.039
microtubule anchoring GO:0034453 8 0.039
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.039
spindle localization GO:0051653 51 0.038
multi organism behavior GO:0051705 389 0.037
cuticle development GO:0042335 100 0.037
cellular macromolecule localization GO:0070727 75 0.037
multi multicellular organism process GO:0044706 390 0.037
cellular protein catabolic process GO:0044257 37 0.036
cell proliferation GO:0008283 116 0.036
germ cell development GO:0007281 351 0.036
positive regulation of rna metabolic process GO:0051254 103 0.036
organelle fission GO:0048285 363 0.035
Human Yeast Zebrafish
mitotic spindle organization GO:0007052 81 0.035
Human
protein localization GO:0008104 205 0.034
multicellular organism growth GO:0035264 385 0.034
cell death GO:0008219 547 0.034
single fertilization GO:0007338 61 0.034
single organism catabolic process GO:0044712 129 0.034
positive regulation of nucleic acid templated transcription GO:1903508 102 0.033
response to abiotic stimulus GO:0009628 152 0.033
posttranscriptional regulation of gene expression GO:0010608 166 0.033
localization of cell GO:0051674 313 0.032
maintenance of protein location GO:0045185 15 0.031
positive regulation of metabolic process GO:0009893 187 0.031
negative regulation of developmental process GO:0051093 227 0.031
aging GO:0007568 812 0.031
gene silencing by rna GO:0031047 143 0.031
embryonic body morphogenesis GO:0010172 49 0.030
death GO:0016265 547 0.030
determination of adult lifespan GO:0008340 812 0.029
positive regulation of developmental growth GO:0048639 354 0.029
ncrna metabolic process GO:0034660 14 0.029
dna templated transcription elongation GO:0006354 1 0.029
small gtpase mediated signal transduction GO:0007264 32 0.028
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.028
Human
dna duplex unwinding GO:0032508 3 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.027
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.027
ribonucleoside monophosphate metabolic process GO:0009161 45 0.027
negative regulation of mitotic cell cycle GO:0045930 42 0.027
regulation of chromosome segregation GO:0051983 20 0.026
multi organism reproductive behavior GO:0044705 387 0.026
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.026
Human
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.026
Human
ras protein signal transduction GO:0007265 31 0.025
organic cyclic compound catabolic process GO:1901361 119 0.024
chromatin modification GO:0016568 32 0.024
behavior GO:0007610 527 0.023
molting cycle GO:0042303 281 0.023
regulation of primary metabolic process GO:0080090 292 0.023
Human
heterocycle catabolic process GO:0046700 119 0.023
membrane organization GO:0061024 135 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.022
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 9 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.021
chromatin assembly or disassembly GO:0006333 1 0.021
innate immune response GO:0045087 190 0.021
rna localization GO:0006403 3 0.020
regulation of cellular biosynthetic process GO:0031326 189 0.020
Human
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.020
cellular component movement GO:0006928 388 0.020
spindle assembly GO:0051225 8 0.020
modification dependent macromolecule catabolic process GO:0043632 32 0.020
regulation of cell communication GO:0010646 176 0.020
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.020
Human
spindle assembly involved in mitosis GO:0090307 6 0.020
cellular protein complex assembly GO:0043623 178 0.019
negative regulation of multicellular organismal process GO:0051241 236 0.019
dna geometric change GO:0032392 3 0.019
small molecule metabolic process GO:0044281 186 0.019
nuclear pore organization GO:0006999 2 0.019
negative regulation of biosynthetic process GO:0009890 65 0.018
Human
embryonic morphogenesis GO:0048598 152 0.018
single organism biosynthetic process GO:0044711 91 0.018
Human
positive regulation of post embryonic development GO:0048582 54 0.018
positive regulation of molecular function GO:0044093 61 0.018
maintenance of location in cell GO:0051651 12 0.017
intracellular signal transduction GO:0035556 96 0.017
positive regulation of cellular protein catabolic process GO:1903364 3 0.017
positive regulation of cellular metabolic process GO:0031325 178 0.017
cellular response to stress GO:0033554 162 0.017
Yeast
chromatin organization GO:0006325 32 0.016
internal peptidyl lysine acetylation GO:0018393 3 0.016
ribonucleoprotein complex biogenesis GO:0022613 8 0.016
attachment of spindle microtubules to kinetochore GO:0008608 8 0.016
response to external biotic stimulus GO:0043207 101 0.016
chromatin remodeling GO:0006338 2 0.016
mitotic sister chromatid separation GO:0051306 13 0.016
oogenesis GO:0048477 229 0.016
positive regulation of chromosome organization GO:2001252 2 0.015
dna packaging GO:0006323 7 0.015
regulation of programmed cell death GO:0043067 50 0.015
protein modification by small protein conjugation or removal GO:0070647 40 0.015
growth GO:0040007 562 0.015
regulation of cell death GO:0010941 65 0.015
regulation of macromolecule biosynthetic process GO:0010556 189 0.015
Human
fertilization GO:0009566 63 0.015
negative regulation of cellular component organization GO:0051129 33 0.015
negative regulation of response to stimulus GO:0048585 73 0.015
chromatin assembly GO:0031497 1 0.014
positive regulation of cell death GO:0010942 38 0.014
mrna catabolic process GO:0006402 16 0.014
negative regulation of cell cycle process GO:0010948 12 0.014
Human
rna catabolic process GO:0006401 21 0.014
cell fate commitment GO:0045165 139 0.014
anatomical structure formation involved in morphogenesis GO:0048646 250 0.014
Yeast
dna repair GO:0006281 23 0.014
Yeast
g1 s transition of mitotic cell cycle GO:0000082 2 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.014
Human
cellular nitrogen compound catabolic process GO:0044270 119 0.013
female gamete generation GO:0007292 254 0.013
positive regulation of macromolecule metabolic process GO:0010604 149 0.013
regulation of atp catabolic process GO:1903289 3 0.013
atp metabolic process GO:0046034 42 0.013
regulation of cytoskeleton organization GO:0051493 41 0.013
defense response GO:0006952 296 0.013
mitotic g2 m transition checkpoint GO:0044818 1 0.013
actin filament based process GO:0030029 191 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.013
Human
negative regulation of rna biosynthetic process GO:1902679 53 0.013
regulation of small gtpase mediated signal transduction GO:0051056 41 0.013
response to external stimulus GO:0009605 289 0.012
regulation of chromatin modification GO:1903308 2 0.012
single organism signaling GO:0044700 401 0.012
Human
cell cycle g1 s phase transition GO:0044843 2 0.012
pronuclear migration GO:0035046 51 0.012
regulation of intracellular signal transduction GO:1902531 77 0.012
aromatic compound catabolic process GO:0019439 116 0.012
regulation of protein targeting GO:1903533 3 0.012
modification dependent protein catabolic process GO:0019941 32 0.012
phosphate containing compound metabolic process GO:0006796 232 0.012
system process GO:0003008 136 0.012
rna polyadenylation GO:0043631 3 0.011
feminization of hermaphroditic germ line GO:0040022 34 0.011
meiosis i GO:0007127 19 0.011
Yeast
male gamete generation GO:0048232 41 0.011
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.011
regulation of cell proliferation GO:0042127 105 0.011
regulation of nucleocytoplasmic transport GO:0046822 3 0.011
regulation of ras protein signal transduction GO:0046578 41 0.011
negative regulation of cellular protein catabolic process GO:1903363 4 0.011
cell surface receptor signaling pathway GO:0007166 149 0.011
regulation of protein import into nucleus GO:0042306 3 0.011
regulation of protein catabolic process GO:0042176 13 0.011
covalent chromatin modification GO:0016569 30 0.011
germ line sex determination GO:0018992 51 0.011
negative regulation of catabolic process GO:0009895 9 0.011
positive regulation of biosynthetic process GO:0009891 109 0.011
protein modification by small protein conjugation GO:0032446 31 0.011
regulation of chromatin organization GO:1902275 2 0.011
digestive system development GO:0055123 122 0.011
regulation of signaling GO:0023051 172 0.011
positive regulation of catalytic activity GO:0043085 59 0.011
regulation of catabolic process GO:0009894 57 0.011
positive regulation of apoptotic process GO:0043065 17 0.011
positive regulation of catabolic process GO:0009896 38 0.011
positive regulation of cellular biosynthetic process GO:0031328 109 0.010
nitrogen compound transport GO:0071705 49 0.010
phosphorylation GO:0016310 116 0.010
hermaphrodite germ line sex determination GO:0040021 48 0.010
positive regulation of protein transport GO:0051222 4 0.010
regulation of apoptotic signaling pathway GO:2001233 1 0.010

smc-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
disease of cellular proliferation DOID:14566 0 0.017
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012