Caenorhabditis elegans

28 known processes

unc-50 (CELE_T07A5.2)

Protein UNC-50

unc-50 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2152 0.405
gene expression GO:0010467 412 0.319
embryo development ending in birth or egg hatching GO:0009792 2992 0.317
locomotion GO:0040011 1634 0.292
embryo development GO:0009790 3052 0.256
localization of cell GO:0051674 313 0.226
regulation of primary metabolic process GO:0080090 292 0.225
endocytosis GO:0006897 819 0.220
single organism organelle organization GO:1902589 501 0.219
cell motility GO:0048870 313 0.217
organelle organization GO:0006996 783 0.211
cell cycle GO:0007049 526 0.210
establishment of localization GO:0051234 1171 0.202
positive regulation of nucleic acid templated transcription GO:1903508 102 0.184
regulation of rna biosynthetic process GO:2001141 165 0.182
regulation of macromolecule metabolic process GO:0060255 421 0.181
cellular component movement GO:0006928 388 0.179
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.174
cell development GO:0048468 696 0.172
macromolecule biosynthetic process GO:0009059 250 0.170
protein metabolic process GO:0019538 422 0.169
signal transduction GO:0007165 317 0.166
biosynthetic process GO:0009058 323 0.157
transport GO:0006810 1093 0.157
organ development GO:0048513 1102 0.154
negative regulation of biological process GO:0048519 567 0.152
axonogenesis GO:0007409 102 0.152
nervous system development GO:0007399 253 0.150
regulation of developmental process GO:0050793 684 0.148
cell projection organization GO:0030030 231 0.147
mitotic spindle organization GO:0007052 81 0.146
cell cycle process GO:0022402 482 0.142
multicellular organism reproduction GO:0032504 819 0.137
multi organism reproductive process GO:0044703 867 0.133
cellular component biogenesis GO:0044085 297 0.132
behavior GO:0007610 527 0.131
developmental process involved in reproduction GO:0003006 1165 0.127
regulation of macromolecule biosynthetic process GO:0010556 189 0.127
vesicle mediated transport GO:0016192 852 0.126
regulation of cellular metabolic process GO:0031323 305 0.126
single organism transport GO:0044765 447 0.123
growth GO:0040007 562 0.123
head development GO:0060322 1 0.118
signaling GO:0023052 401 0.117
regulation of multicellular organismal development GO:2000026 317 0.116
cytoskeleton organization GO:0007010 339 0.116
single organism reproductive process GO:0044702 1196 0.115
nucleobase containing compound metabolic process GO:0006139 406 0.114
cell migration GO:0016477 306 0.112
cellular macromolecule biosynthetic process GO:0034645 247 0.111
regulation of transcription dna templated GO:0006355 164 0.106
cellular biosynthetic process GO:0044249 315 0.104
receptor mediated endocytosis GO:0006898 715 0.103
organic substance biosynthetic process GO:1901576 323 0.102
lamellipodium organization GO:0097581 2 0.101
regulation of cellular biosynthetic process GO:0031326 189 0.101
response to external stimulus GO:0009605 289 0.099
regulation of vulval development GO:0040028 248 0.099
cell morphogenesis GO:0000902 163 0.099
rna metabolic process GO:0016070 228 0.099
body morphogenesis GO:0010171 620 0.098
macromolecule localization GO:0033036 771 0.098
neuron projection development GO:0031175 187 0.097
nucleic acid templated transcription GO:0097659 169 0.096
oviposition GO:0018991 364 0.094
mitotic cell cycle process GO:1903047 194 0.094
regulation of biosynthetic process GO:0009889 189 0.094
regulation of multicellular organismal process GO:0051239 726 0.092
regulation of locomotion GO:0040012 161 0.092
tissue development GO:0009888 112 0.092
positive regulation of macromolecule metabolic process GO:0010604 149 0.092
regulation of gene expression GO:0010468 366 0.089
cellular localization GO:0051641 360 0.089
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.089
sexual reproduction GO:0019953 546 0.089
cellular component assembly GO:0022607 293 0.089
aromatic compound biosynthetic process GO:0019438 192 0.085
chromosome organization GO:0051276 104 0.085
regulation of nucleic acid templated transcription GO:1903506 165 0.084
neurogenesis GO:0022008 236 0.083
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.082
regulation of cellular component organization GO:0051128 248 0.082
vulval development GO:0040025 333 0.082
rna biosynthetic process GO:0032774 169 0.081
regulation of nematode larval development GO:0061062 260 0.081
multicellular organismal reproductive process GO:0048609 815 0.079
organelle fission GO:0048285 363 0.079
protein complex subunit organization GO:0071822 280 0.078
oogenesis GO:0048477 229 0.078
transcription dna templated GO:0006351 168 0.076
development of primary sexual characteristics GO:0045137 840 0.076
positive regulation of metabolic process GO:0009893 187 0.076
positive regulation of cellular metabolic process GO:0031325 178 0.075
reproductive system development GO:0061458 850 0.075
regulation of developmental growth GO:0048638 389 0.075
phosphorus metabolic process GO:0006793 232 0.075
nucleic acid metabolic process GO:0090304 299 0.073
cell part morphogenesis GO:0032990 152 0.073
cellular protein metabolic process GO:0044267 279 0.072
multicellular organismal reproductive behavior GO:0033057 384 0.071
heterocycle biosynthetic process GO:0018130 187 0.071
generation of neurons GO:0048699 235 0.071
lipid localization GO:0010876 573 0.071
tube development GO:0035295 126 0.070
single organism localization GO:1902578 518 0.070
maintenance of location GO:0051235 580 0.069
regulation of nitrogen compound metabolic process GO:0051171 222 0.069
nucleobase containing compound biosynthetic process GO:0034654 184 0.067
multicellular organism growth GO:0035264 385 0.067
regulation of biological quality GO:0065008 741 0.066
positive regulation of gene expression GO:0010628 112 0.066
lipid storage GO:0019915 565 0.066
regulation of rna metabolic process GO:0051252 173 0.066
positive regulation of cellular biosynthetic process GO:0031328 109 0.065
negative regulation of cellular process GO:0048523 239 0.065
protein localization GO:0008104 205 0.065
regulation of cell motility GO:2000145 57 0.065
negative regulation of macromolecule metabolic process GO:0010605 229 0.064
gonad development GO:0008406 840 0.064
macromolecular complex subunit organization GO:0043933 320 0.064
epithelium development GO:0060429 68 0.063
organic cyclic compound biosynthetic process GO:1901362 195 0.063
aging GO:0007568 812 0.063
developmental growth GO:0048589 412 0.063
mitotic nuclear division GO:0007067 89 0.062
axon development GO:0061564 163 0.062
multicellular organismal aging GO:0010259 812 0.062
neuron differentiation GO:0030182 217 0.061
regulation of cellular component movement GO:0051270 62 0.061
cell death GO:0008219 547 0.061
regulation of growth GO:0040008 409 0.061
positive regulation of transcription dna templated GO:0045893 102 0.061
germ cell development GO:0007281 351 0.061
response to chemical GO:0042221 356 0.060
positive regulation of developmental growth GO:0048639 354 0.059
apoptotic cell clearance GO:0043277 111 0.059
meiotic cell cycle GO:0051321 335 0.059
phagocytosis GO:0006909 115 0.058
positive regulation of rna biosynthetic process GO:1902680 102 0.058
regulation of signaling GO:0023051 172 0.057
cellular response to organic substance GO:0071310 119 0.056
cellular catabolic process GO:0044248 199 0.056
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.055
cell morphogenesis involved in differentiation GO:0000904 112 0.055
cellular macromolecular complex assembly GO:0034622 184 0.055
protein modification process GO:0036211 207 0.054
positive regulation of multicellular organism growth GO:0040018 352 0.054
reproductive structure development GO:0048608 850 0.054
post embryonic organ development GO:0048569 336 0.053
regulation of cell cycle GO:0051726 194 0.052
cellular component morphogenesis GO:0032989 318 0.052
genitalia development GO:0048806 741 0.052
heterocycle catabolic process GO:0046700 119 0.052
spindle organization GO:0007051 92 0.052
cellular nitrogen compound biosynthetic process GO:0044271 192 0.052
defense response GO:0006952 296 0.052
gamete generation GO:0007276 461 0.052
cellular protein modification process GO:0006464 207 0.051
regulation of multicellular organism growth GO:0040014 373 0.051
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.050
regulation of metabolic process GO:0019222 478 0.050
reproductive behavior GO:0019098 387 0.050
establishment of localization in cell GO:0051649 318 0.050
organic substance catabolic process GO:1901575 294 0.049
cell projection morphogenesis GO:0048858 148 0.048
digestive system development GO:0055123 122 0.048
meiotic cell cycle process GO:1903046 170 0.048
sensory organ morphogenesis GO:0090596 2 0.046
secretion by cell GO:0032940 138 0.046
positive regulation of rna metabolic process GO:0051254 103 0.046
meiotic nuclear division GO:0007126 300 0.045
cellular protein complex assembly GO:0043623 178 0.044
catabolic process GO:0009056 318 0.044
macromolecule modification GO:0043412 218 0.044
macromolecular complex assembly GO:0065003 193 0.044
negative regulation of metabolic process GO:0009892 240 0.043
transcription from rna polymerase ii promoter GO:0006366 149 0.043
organelle assembly GO:0070925 214 0.043
regulation of response to stimulus GO:0048583 243 0.043
anatomical structure formation involved in morphogenesis GO:0048646 250 0.042
programmed cell death GO:0012501 500 0.042
negative regulation of gene expression GO:0010629 217 0.042
multi multicellular organism process GO:0044706 390 0.042
positive regulation of growth GO:0045927 369 0.041
phosphate containing compound metabolic process GO:0006796 232 0.041
aromatic compound catabolic process GO:0019439 116 0.041
negative regulation of developmental process GO:0051093 227 0.041
hermaphrodite genitalia development GO:0040035 734 0.041
embryonic morphogenesis GO:0048598 152 0.040
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.040
small molecule metabolic process GO:0044281 186 0.040
determination of adult lifespan GO:0008340 812 0.040
regulation of post embryonic development GO:0048580 260 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.039
apoptotic process GO:0006915 478 0.039
purine containing compound metabolic process GO:0072521 95 0.038
regulation of catalytic activity GO:0050790 78 0.038
establishment of spindle localization GO:0051293 51 0.038
regulation of cell division GO:0051302 142 0.038
positive regulation of cellular process GO:0048522 332 0.037
actin filament based process GO:0030029 191 0.037
negative regulation of multicellular organismal process GO:0051241 236 0.037
intracellular signal transduction GO:0035556 96 0.036
protein complex assembly GO:0006461 186 0.036
cellular nitrogen compound catabolic process GO:0044270 119 0.036
purine nucleoside metabolic process GO:0042278 92 0.035
regulation of cell migration GO:0030334 55 0.035
inductive cell migration GO:0040039 145 0.035
establishment of mitotic spindle localization GO:0040001 41 0.035
organelle localization GO:0051640 127 0.035
regulation of gene expression epigenetic GO:0040029 163 0.035
sex differentiation GO:0007548 909 0.034
neuron development GO:0048666 199 0.034
cell division GO:0051301 262 0.034
establishment of organelle localization GO:0051656 123 0.033
spindle localization GO:0051653 51 0.033
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.033
carbohydrate derivative metabolic process GO:1901135 141 0.033
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.033
positive regulation of developmental process GO:0051094 408 0.033
purine nucleoside catabolic process GO:0006152 75 0.032
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.032
muscle tissue development GO:0060537 1 0.032
organic cyclic compound catabolic process GO:1901361 119 0.032
single organism signaling GO:0044700 401 0.032
multi organism reproductive behavior GO:0044705 387 0.031
tissue morphogenesis GO:0048729 65 0.031
ribosome biogenesis GO:0042254 4 0.030
positive regulation of multicellular organismal process GO:0051240 417 0.030
positive regulation of biosynthetic process GO:0009891 109 0.030
female gamete generation GO:0007292 254 0.029
secretion GO:0046903 147 0.029
neuron projection morphogenesis GO:0048812 114 0.029
positive regulation of cell projection organization GO:0031346 4 0.029
regulation of molecular function GO:0065009 89 0.029
membrane organization GO:0061024 135 0.029
positive regulation of catalytic activity GO:0043085 59 0.028
organonitrogen compound metabolic process GO:1901564 151 0.028
digestive tract morphogenesis GO:0048546 76 0.028
protein complex biogenesis GO:0070271 186 0.028
regulation of cell communication GO:0010646 176 0.028
single organism cellular localization GO:1902580 72 0.028
nucleoside phosphate metabolic process GO:0006753 108 0.027
regulation of localization GO:0032879 194 0.027
axon guidance GO:0007411 82 0.027
nucleotide metabolic process GO:0009117 108 0.027
ribonucleoprotein complex assembly GO:0022618 4 0.026
epithelial cell proliferation GO:0050673 1 0.026
intracellular transport GO:0046907 77 0.026
organonitrogen compound catabolic process GO:1901565 90 0.026
organophosphate metabolic process GO:0019637 125 0.025
regulation of phosphorus metabolic process GO:0051174 81 0.025
positive regulation of neuron differentiation GO:0045666 4 0.025
protein phosphorylation GO:0006468 85 0.025
dauer larval development GO:0040024 92 0.025
pattern specification process GO:0007389 59 0.025
cell adhesion GO:0007155 21 0.025
purine ribonucleotide catabolic process GO:0009154 75 0.025
multi organism behavior GO:0051705 389 0.024
single organism intracellular transport GO:1902582 70 0.024
golgi vesicle transport GO:0048193 3 0.024
engulfment of apoptotic cell GO:0043652 94 0.024
death GO:0016265 547 0.024
epithelial tube morphogenesis GO:0060562 1 0.024
regulation of organelle organization GO:0033043 164 0.023
cell substrate adhesion GO:0031589 1 0.023
macromolecule catabolic process GO:0009057 202 0.023
cell projection assembly GO:0030031 35 0.023
negative regulation of cellular metabolic process GO:0031324 95 0.023
regulation of signal transduction GO:0009966 135 0.023
gtp catabolic process GO:0006184 46 0.022
lamellipodium assembly GO:0030032 2 0.022
cell proliferation GO:0008283 116 0.022
regulation of cell cycle process GO:0010564 145 0.022
synaptic growth at neuromuscular junction GO:0051124 1 0.022
regulation of lamellipodium assembly GO:0010591 1 0.021
immune response GO:0006955 192 0.021
molting cycle GO:0042303 281 0.021
digestive tract development GO:0048565 122 0.021
membrane invagination GO:0010324 98 0.021
actin cytoskeleton organization GO:0030036 184 0.021
cell surface receptor signaling pathway GO:0007166 149 0.021
organ morphogenesis GO:0009887 67 0.020
ribonucleoside triphosphate metabolic process GO:0009199 87 0.020
regulation of cell projection assembly GO:0060491 3 0.020
regulation of meiosis GO:0040020 94 0.020
peptidyl serine modification GO:0018209 20 0.020
purine ribonucleoside metabolic process GO:0046128 92 0.020
chemotaxis GO:0006935 120 0.019
organophosphate catabolic process GO:0046434 81 0.019
cilium morphogenesis GO:0060271 33 0.019
regulation of cell differentiation GO:0045595 81 0.019
regulation of cell proliferation GO:0042127 105 0.019
peptidyl amino acid modification GO:0018193 58 0.019
axonal fasciculation GO:0007413 79 0.019
dna metabolic process GO:0006259 74 0.019
single organism catabolic process GO:0044712 129 0.019
ribonucleotide catabolic process GO:0009261 75 0.019
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.019
positive regulation of neurogenesis GO:0050769 4 0.019
cell fate commitment GO:0045165 139 0.019
cell type specific apoptotic process GO:0097285 4 0.019
guanosine containing compound catabolic process GO:1901069 48 0.019
purine containing compound catabolic process GO:0072523 75 0.018
fertilization GO:0009566 63 0.018
nucleoside triphosphate metabolic process GO:0009141 87 0.018
phagocytosis engulfment GO:0006911 98 0.018
cellular component assembly involved in morphogenesis GO:0010927 183 0.018
response to biotic stimulus GO:0009607 101 0.018
posttranscriptional gene silencing by rna GO:0035194 143 0.018
filopodium assembly GO:0046847 2 0.018
organic acid metabolic process GO:0006082 47 0.018
nucleobase containing compound catabolic process GO:0034655 114 0.018
muscle structure development GO:0061061 191 0.018
regulation of phosphate metabolic process GO:0019220 81 0.018
regulation of cytoskeleton organization GO:0051493 41 0.018
system process GO:0003008 136 0.017
positive regulation of molecular function GO:0044093 61 0.017
regulation of protein metabolic process GO:0051246 81 0.017
regulation of intracellular signal transduction GO:1902531 77 0.017
striated muscle cell differentiation GO:0051146 158 0.017
muscle cell differentiation GO:0042692 171 0.017
meiotic chromosome segregation GO:0045132 139 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.017
posttranscriptional gene silencing GO:0016441 143 0.017
canonical wnt signaling pathway GO:0060070 3 0.017
ribonucleoside metabolic process GO:0009119 98 0.017
defense response to other organism GO:0098542 100 0.016
neuromuscular junction development GO:0007528 2 0.016
neuron recognition GO:0008038 83 0.016
negative regulation of neurogenesis GO:0050768 4 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.016
regulation of cytoplasmic transport GO:1903649 3 0.016
ribonucleotide metabolic process GO:0009259 99 0.016
nucleus organization GO:0006997 38 0.016
organic substance transport GO:0071702 113 0.015
posttranscriptional regulation of gene expression GO:0010608 166 0.015
ras protein signal transduction GO:0007265 31 0.015
taxis GO:0042330 128 0.015
negative regulation of nematode larval development GO:0061064 208 0.015
muscle cell development GO:0055001 158 0.015
small gtpase mediated signal transduction GO:0007264 32 0.015
biological adhesion GO:0022610 21 0.015
ribonucleoside catabolic process GO:0042454 77 0.015
response to external biotic stimulus GO:0043207 101 0.015
neuron projection guidance GO:0097485 82 0.014
striated muscle cell development GO:0055002 157 0.014
nucleotide catabolic process GO:0009166 77 0.014
phosphorylation GO:0016310 116 0.014
regulation of translation GO:0006417 19 0.014
purine nucleoside triphosphate metabolic process GO:0009144 87 0.014
regulation of epithelial cell proliferation GO:0050678 1 0.014
purine ribonucleotide metabolic process GO:0009150 95 0.014
nucleoside metabolic process GO:0009116 99 0.014
response to abiotic stimulus GO:0009628 152 0.014
glycosyl compound metabolic process GO:1901657 100 0.014
guanosine containing compound metabolic process GO:1901068 49 0.014
regulation of organ morphogenesis GO:2000027 4 0.014
purine nucleoside triphosphate catabolic process GO:0009146 72 0.013
axon extension GO:0048675 37 0.013
single fertilization GO:0007338 61 0.013
carbohydrate derivative catabolic process GO:1901136 82 0.013
rho protein signal transduction GO:0007266 2 0.013
localization within membrane GO:0051668 2 0.013
gene silencing by rna GO:0031047 143 0.013
tube morphogenesis GO:0035239 79 0.013
defense response to bacterium GO:0042742 86 0.013
striated muscle myosin thick filament assembly GO:0071688 138 0.013
ribose phosphate metabolic process GO:0019693 99 0.013
gene silencing GO:0016458 143 0.013
regulation of actin filament based process GO:0032970 22 0.012
gastrulation GO:0007369 58 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.012
rna interference GO:0016246 137 0.012
cell matrix adhesion GO:0007160 1 0.012
collagen and cuticulin based cuticle development GO:0040002 99 0.012
protein oligomerization GO:0051259 4 0.012
regulation of axonogenesis GO:0050770 24 0.012
ribonucleoside triphosphate catabolic process GO:0009203 72 0.012
negative regulation of rna biosynthetic process GO:1902679 53 0.012
positive regulation of signal transduction GO:0009967 40 0.012
regulation of cellular protein metabolic process GO:0032268 75 0.012
glycosyl compound catabolic process GO:1901658 79 0.012
negative regulation of post embryonic development GO:0048581 208 0.012
cellular macromolecule localization GO:0070727 75 0.012
gtp metabolic process GO:0046039 46 0.012
regeneration GO:0031099 4 0.012
myofibril assembly GO:0030239 154 0.012
nucleoside triphosphate catabolic process GO:0009143 72 0.012
nucleoside phosphate catabolic process GO:1901292 77 0.012
synaptic vesicle recycling GO:0036465 3 0.012
cell cycle g1 s phase transition GO:0044843 2 0.012
nucleobase containing small molecule metabolic process GO:0055086 115 0.012
muscle fiber development GO:0048747 2 0.011
negative regulation of gene expression epigenetic GO:0045814 2 0.011
oxoacid metabolic process GO:0043436 47 0.011
myosin filament organization GO:0031033 138 0.011
cellular protein localization GO:0034613 75 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.011
regulation of cell morphogenesis GO:0022604 40 0.011
regulation of axon extension GO:0030516 20 0.011
negative regulation of signal transduction GO:0009968 60 0.011
regulation of protein kinase activity GO:0045859 28 0.011
establishment or maintenance of cell polarity GO:0007163 63 0.011
single organism carbohydrate metabolic process GO:0044723 29 0.011
positive regulation of hydrolase activity GO:0051345 38 0.011
regulation of lamellipodium organization GO:1902743 1 0.011
g1 s transition of mitotic cell cycle GO:0000082 2 0.011
purine ribonucleoside catabolic process GO:0046130 75 0.011
positive regulation of vulval development GO:0040026 52 0.011
vesicle organization GO:0016050 15 0.011
regulation of calcium ion transport GO:0051924 3 0.011
neuron apoptotic process GO:0051402 4 0.011
regulation of meiotic cell cycle GO:0051445 136 0.010
chromatin assembly or disassembly GO:0006333 1 0.010
response to wounding GO:0009611 4 0.010
response to other organism GO:0051707 101 0.010
regulation of phosphorylation GO:0042325 45 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
negative regulation of cellular biosynthetic process GO:0031327 65 0.010
single organism behavior GO:0044708 83 0.010

unc-50 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012