Caenorhabditis elegans

46 known processes

sun-1 (CELE_F57B1.2)

Protein SUN-1

sun-1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.984
embryo development GO:0009790 3052 0.919
post embryonic development GO:0009791 2152 0.862
regulation of vulval development GO:0040028 248 0.763
multicellular organism reproduction GO:0032504 819 0.725
single organism reproductive process GO:0044702 1196 0.693
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.675
developmental process involved in reproduction GO:0003006 1165 0.673
locomotion GO:0040011 1634 0.659
multicellular organismal reproductive process GO:0048609 815 0.620
regulation of primary metabolic process GO:0080090 292 0.584
oogenesis GO:0048477 229 0.574
meiotic cell cycle process GO:1903046 170 0.565
cell cycle GO:0007049 526 0.556
protein modification process GO:0036211 207 0.549
germ cell development GO:0007281 351 0.523
sexual reproduction GO:0019953 546 0.514
meiotic nuclear division GO:0007126 300 0.493
cell cycle process GO:0022402 482 0.473
organelle organization GO:0006996 783 0.462
meiotic chromosome segregation GO:0045132 139 0.460
meiotic cell cycle GO:0051321 335 0.456
gamete generation GO:0007276 461 0.425
sex differentiation GO:0007548 909 0.424
vulval development GO:0040025 333 0.415
cell development GO:0048468 696 0.401
multicellular organismal reproductive behavior GO:0033057 384 0.373
cellular component assembly GO:0022607 293 0.365
oviposition GO:0018991 364 0.362
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.347
cellular protein metabolic process GO:0044267 279 0.300
female gamete generation GO:0007292 254 0.290
cellular nitrogen compound biosynthetic process GO:0044271 192 0.288
negative regulation of nematode larval development GO:0061064 208 0.286
protein metabolic process GO:0019538 422 0.284
regulation of cellular metabolic process GO:0031323 305 0.280
gonad development GO:0008406 840 0.261
reproductive behavior GO:0019098 387 0.260
organelle fission GO:0048285 363 0.260
multi organism reproductive behavior GO:0044705 387 0.255
nucleobase containing compound biosynthetic process GO:0034654 184 0.248
cell fate commitment GO:0045165 139 0.244
regulation of multicellular organismal development GO:2000026 317 0.241
gene expression GO:0010467 412 0.240
regulation of rna biosynthetic process GO:2001141 165 0.236
multi organism reproductive process GO:0044703 867 0.230
determination of adult lifespan GO:0008340 812 0.227
organic substance biosynthetic process GO:1901576 323 0.227
cellular component morphogenesis GO:0032989 318 0.215
macromolecule modification GO:0043412 218 0.214
cellular macromolecule biosynthetic process GO:0034645 247 0.212
negative regulation of vulval development GO:0040027 206 0.208
chromosome segregation GO:0007059 180 0.203
single organism organelle organization GO:1902589 501 0.198
positive regulation of growth GO:0045927 369 0.197
regulation of post embryonic development GO:0048580 260 0.196
cellular component biogenesis GO:0044085 297 0.189
chromosome organization GO:0051276 104 0.186
regulation of multicellular organismal process GO:0051239 726 0.184
oocyte differentiation GO:0009994 45 0.184
macromolecular complex subunit organization GO:0043933 320 0.183
regulation of developmental growth GO:0048638 389 0.180
regulation of nitrogen compound metabolic process GO:0051171 222 0.177
development of primary sexual characteristics GO:0045137 840 0.177
reproductive structure development GO:0048608 850 0.174
reproductive system development GO:0061458 850 0.174
hermaphrodite genitalia development GO:0040035 734 0.168
organ development GO:0048513 1102 0.163
negative regulation of multicellular organismal process GO:0051241 236 0.162
post embryonic organ development GO:0048569 336 0.157
negative regulation of post embryonic development GO:0048581 208 0.157
genitalia development GO:0048806 741 0.157
biosynthetic process GO:0009058 323 0.155
actin filament based process GO:0030029 191 0.154
protein complex subunit organization GO:0071822 280 0.151
organelle localization GO:0051640 127 0.149
regulation of meiotic cell cycle GO:0051445 136 0.142
regulation of cell division GO:0051302 142 0.142
single organism signaling GO:0044700 401 0.139
rna metabolic process GO:0016070 228 0.138
behavior GO:0007610 527 0.136
negative regulation of biological process GO:0048519 567 0.136
multi multicellular organism process GO:0044706 390 0.135
regulation of nematode larval development GO:0061062 260 0.134
multi organism behavior GO:0051705 389 0.133
vesicle mediated transport GO:0016192 852 0.133
anatomical structure formation involved in morphogenesis GO:0048646 250 0.133
heterocycle biosynthetic process GO:0018130 187 0.132
regulation of multicellular organism growth GO:0040014 373 0.128
positive regulation of developmental growth GO:0048639 354 0.128
aging GO:0007568 812 0.127
endocytosis GO:0006897 819 0.127
death GO:0016265 547 0.126
single organism localization GO:1902578 518 0.125
nucleic acid metabolic process GO:0090304 299 0.125
positive regulation of multicellular organismal process GO:0051240 417 0.124
oocyte development GO:0048599 44 0.124
macromolecular complex assembly GO:0065003 193 0.119
regulation of nucleic acid templated transcription GO:1903506 165 0.118
catabolic process GO:0009056 318 0.117
stem cell proliferation GO:0072089 9 0.116
nucleobase containing compound metabolic process GO:0006139 406 0.111
sister chromatid segregation GO:0000819 46 0.109
regulation of biological quality GO:0065008 741 0.108
regulation of transcription dna templated GO:0006355 164 0.107
microtubule based process GO:0007017 182 0.107
establishment of localization GO:0051234 1171 0.106
regulation of meiosis GO:0040020 94 0.105
organelle assembly GO:0070925 214 0.105
macromolecule localization GO:0033036 771 0.105
cellular biosynthetic process GO:0044249 315 0.104
regulation of macromolecule metabolic process GO:0060255 421 0.103
chromosome organization involved in meiosis GO:0070192 25 0.102
cellular protein complex assembly GO:0043623 178 0.102
establishment of localization in cell GO:0051649 318 0.102
cellular localization GO:0051641 360 0.101
positive regulation of developmental process GO:0051094 408 0.101
regulation of metabolic process GO:0019222 478 0.100
multicellular organismal aging GO:0010259 812 0.100
regulation of mitotic cell cycle GO:0007346 76 0.099
macromolecule biosynthetic process GO:0009059 250 0.096
regulation of growth GO:0040008 409 0.094
growth GO:0040007 562 0.094
programmed cell death GO:0012501 500 0.093
positive regulation of macromolecule metabolic process GO:0010604 149 0.092
positive regulation of multicellular organism growth GO:0040018 352 0.092
regulation of rna metabolic process GO:0051252 173 0.091
regulation of gene expression GO:0010468 366 0.091
cell death GO:0008219 547 0.090
cytoskeleton organization GO:0007010 339 0.090
negative regulation of developmental process GO:0051093 227 0.089
aromatic compound biosynthetic process GO:0019438 192 0.089
cell cell signaling GO:0007267 118 0.088
regulation of biosynthetic process GO:0009889 189 0.088
regulation of developmental process GO:0050793 684 0.088
transport GO:0006810 1093 0.087
negative regulation of cellular process GO:0048523 239 0.087
cell division GO:0051301 262 0.081
protein complex biogenesis GO:0070271 186 0.080
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.077
multicellular organism growth GO:0035264 385 0.074
regulation of nuclear division GO:0051783 115 0.072
rna biosynthetic process GO:0032774 169 0.072
cell surface receptor signaling pathway GO:0007166 149 0.071
phosphate containing compound metabolic process GO:0006796 232 0.069
positive regulation of cellular process GO:0048522 332 0.069
developmental growth GO:0048589 412 0.069
apoptotic process GO:0006915 478 0.068
cell proliferation GO:0008283 116 0.068
negative regulation of transcription dna templated GO:0045892 53 0.067
transcription dna templated GO:0006351 168 0.067
regulation of response to stimulus GO:0048583 243 0.067
striated muscle cell differentiation GO:0051146 158 0.066
single organism transport GO:0044765 447 0.066
negative regulation of gene expression GO:0010629 217 0.065
response to abiotic stimulus GO:0009628 152 0.064
negative regulation of metabolic process GO:0009892 240 0.064
signal transduction GO:0007165 317 0.063
neuroblast proliferation GO:0007405 9 0.063
regulation of cell cycle GO:0051726 194 0.063
muscle tissue development GO:0060537 1 0.062
receptor mediated endocytosis GO:0006898 715 0.062
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.062
maintenance of location GO:0051235 580 0.061
lipid storage GO:0019915 565 0.061
cellular macromolecular complex assembly GO:0034622 184 0.060
striated muscle cell development GO:0055002 157 0.060
cellular protein modification process GO:0006464 207 0.060
regulation of organelle organization GO:0033043 164 0.058
protein complex assembly GO:0006461 186 0.056
positive regulation of chromosome segregation GO:0051984 1 0.056
defense response GO:0006952 296 0.054
regulation of cellular biosynthetic process GO:0031326 189 0.054
generation of neurons GO:0048699 235 0.054
secretion by cell GO:0032940 138 0.053
response to chemical GO:0042221 356 0.053
macromolecule catabolic process GO:0009057 202 0.053
signaling GO:0023052 401 0.053
muscle cell development GO:0055001 158 0.052
regulation of signal transduction GO:0009966 135 0.052
muscle structure development GO:0061061 191 0.052
actin cytoskeleton organization GO:0030036 184 0.051
cellular component assembly involved in morphogenesis GO:0010927 183 0.051
synapsis GO:0007129 10 0.051
striated muscle myosin thick filament assembly GO:0071688 138 0.050
myofibril assembly GO:0030239 154 0.050
regulation of cell cycle process GO:0010564 145 0.049
negative regulation of macromolecule metabolic process GO:0010605 229 0.049
spindle organization GO:0007051 92 0.049
covalent chromatin modification GO:0016569 30 0.049
actomyosin structure organization GO:0031032 154 0.048
regulation of chromosome organization GO:0033044 20 0.047
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.047
regulation of macromolecule biosynthetic process GO:0010556 189 0.045
mitotic spindle organization GO:0007052 81 0.045
body morphogenesis GO:0010171 620 0.045
lipid localization GO:0010876 573 0.044
mrna metabolic process GO:0016071 31 0.044
pattern specification process GO:0007389 59 0.044
small molecule metabolic process GO:0044281 186 0.043
neural precursor cell proliferation GO:0061351 9 0.041
neuron projection guidance GO:0097485 82 0.041
muscle cell differentiation GO:0042692 171 0.040
cytoskeleton dependent cytokinesis GO:0061640 35 0.039
synaptic transmission GO:0007268 106 0.038
nervous system development GO:0007399 253 0.038
spermatogenesis GO:0007283 41 0.037
neuron development GO:0048666 199 0.037
tube morphogenesis GO:0035239 79 0.037
positive regulation of metabolic process GO:0009893 187 0.037
regulation of mitotic metaphase anaphase transition GO:0030071 5 0.037
tissue development GO:0009888 112 0.036
negative regulation of cell cycle GO:0045786 53 0.036
posttranscriptional regulation of gene expression GO:0010608 166 0.036
transcription from rna polymerase ii promoter GO:0006366 149 0.036
tube development GO:0035295 126 0.036
myosin filament organization GO:0031033 138 0.035
cellular response to abiotic stimulus GO:0071214 4 0.035
axon development GO:0061564 163 0.034
mitotic nuclear division GO:0007067 89 0.034
primary mirna processing GO:0031053 3 0.034
tissue morphogenesis GO:0048729 65 0.034
nucleic acid templated transcription GO:0097659 169 0.033
mitotic cell cycle process GO:1903047 194 0.033
negative regulation of rna biosynthetic process GO:1902679 53 0.033
cell projection organization GO:0030030 231 0.033
neuronal stem cell division GO:0036445 9 0.032
male gamete generation GO:0048232 41 0.032
fertilization GO:0009566 63 0.031
head development GO:0060322 1 0.031
cell recognition GO:0008037 85 0.031
organic cyclic compound biosynthetic process GO:1901362 195 0.030
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.030
myosin filament assembly GO:0031034 138 0.029
regulation of organ morphogenesis GO:2000027 4 0.029
sensory organ morphogenesis GO:0090596 2 0.029
chromatin organization GO:0006325 32 0.029
phosphorylation GO:0016310 116 0.029
cellular nitrogen compound catabolic process GO:0044270 119 0.029
cellular catabolic process GO:0044248 199 0.029
mitotic sister chromatid segregation GO:0000070 38 0.029
hatching GO:0035188 48 0.028
protein catabolic process GO:0030163 162 0.028
dna metabolic process GO:0006259 74 0.028
negative regulation of cellular metabolic process GO:0031324 95 0.028
protein localization GO:0008104 205 0.028
oxoacid metabolic process GO:0043436 47 0.028
gene silencing GO:0016458 143 0.027
positive regulation of mitotic sister chromatid separation GO:1901970 1 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.027
regulation of cell communication GO:0010646 176 0.027
asymmetric neuroblast division GO:0055059 8 0.027
organonitrogen compound metabolic process GO:1901564 151 0.027
negative regulation of signaling GO:0023057 61 0.026
establishment of cell polarity GO:0030010 46 0.026
axonogenesis GO:0007409 102 0.026
regulation of mitosis GO:0007088 18 0.026
cytokinesis GO:0000910 80 0.025
regulation of chromosome segregation GO:0051983 20 0.025
response to organic substance GO:0010033 131 0.025
somatic stem cell division GO:0048103 9 0.024
cell morphogenesis GO:0000902 163 0.024
histone modification GO:0016570 30 0.024
positive regulation of rna biosynthetic process GO:1902680 102 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.024
rna localization GO:0006403 3 0.024
negative regulation of biosynthetic process GO:0009890 65 0.024
positive regulation of cell cycle GO:0045787 55 0.024
cellular response to organic substance GO:0071310 119 0.023
neuron projection development GO:0031175 187 0.023
negative regulation of mitotic cell cycle GO:0045930 42 0.023
regulation of cellular ketone metabolic process GO:0010565 3 0.023
neuron projection morphogenesis GO:0048812 114 0.022
meiotic cytokinesis GO:0033206 15 0.022
neuron differentiation GO:0030182 217 0.022
neuron recognition GO:0008038 83 0.022
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.022
cellular ketone metabolic process GO:0042180 14 0.022
secretion GO:0046903 147 0.022
establishment of organelle localization GO:0051656 123 0.022
organic substance catabolic process GO:1901575 294 0.022
regulation of lipid metabolic process GO:0019216 4 0.021
digestive tract development GO:0048565 122 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.021
spindle assembly GO:0051225 8 0.021
translation GO:0006412 37 0.021
rna processing GO:0006396 34 0.021
negative regulation of nucleic acid templated transcription GO:1903507 53 0.021
defense response to bacterium GO:0042742 86 0.020
cell motility GO:0048870 313 0.020
negative regulation of signal transduction GO:0009968 60 0.020
regulation of protein metabolic process GO:0051246 81 0.020
regulation of signaling GO:0023051 172 0.020
regulation of cellular component organization GO:0051128 248 0.020
chromosome localization GO:0050000 10 0.019
organic acid metabolic process GO:0006082 47 0.019
positive regulation of rna metabolic process GO:0051254 103 0.019
synaptonemal complex organization GO:0070193 8 0.019
stem cell division GO:0017145 18 0.019
protein phosphorylation GO:0006468 85 0.019
positive regulation of cell projection organization GO:0031346 4 0.018
positive regulation of nucleic acid templated transcription GO:1903508 102 0.018
cellular protein localization GO:0034613 75 0.018
dna recombination GO:0006310 19 0.018
cellular macromolecule catabolic process GO:0044265 73 0.018
negative regulation of neurogenesis GO:0050768 4 0.018
positive regulation of neuron differentiation GO:0045666 4 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.018
system process GO:0003008 136 0.018
intracellular signal transduction GO:0035556 96 0.018
regulation of synaptic plasticity GO:0048167 1 0.018
cellular component movement GO:0006928 388 0.018
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.018
regulation of gene expression epigenetic GO:0040029 163 0.017
neurogenesis GO:0022008 236 0.017
asymmetric stem cell division GO:0098722 8 0.017
oocyte axis specification GO:0007309 2 0.017
oocyte construction GO:0007308 2 0.017
establishment or maintenance of cell polarity GO:0007163 63 0.017
mitotic cell cycle phase transition GO:0044772 13 0.017
neurological system process GO:0050877 53 0.017
aromatic compound catabolic process GO:0019439 116 0.016
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 35 0.016
regulation of sister chromatid segregation GO:0033045 16 0.016
meiosis i GO:0007127 19 0.016
regulation of cellular protein metabolic process GO:0032268 75 0.016
regulation of intracellular signal transduction GO:1902531 77 0.016
cell type specific apoptotic process GO:0097285 4 0.016
cell part morphogenesis GO:0032990 152 0.016
positive regulation of biosynthetic process GO:0009891 109 0.016
female meiotic division GO:0007143 17 0.016
synaptonemal complex assembly GO:0007130 6 0.016
polar body extrusion after meiotic divisions GO:0040038 14 0.015
positive regulation of chromosome organization GO:2001252 2 0.015
response to wounding GO:0009611 4 0.015
metaphase anaphase transition of mitotic cell cycle GO:0007091 10 0.015
nucleus localization GO:0051647 55 0.015
single organism catabolic process GO:0044712 129 0.015
response to temperature stimulus GO:0009266 66 0.015
negative regulation of protein metabolic process GO:0051248 27 0.015
axonal fasciculation GO:0007413 79 0.015
positive regulation of meiotic cell cycle GO:0051446 47 0.015
mitotic sister chromatid separation GO:0051306 13 0.014
neuromuscular junction development GO:0007528 2 0.014
protein oligomerization GO:0051259 4 0.014
response to external stimulus GO:0009605 289 0.014
chromosome separation GO:0051304 19 0.014
regulation of cell proliferation GO:0042127 105 0.014
response to bacterium GO:0009617 86 0.014
chromatin assembly or disassembly GO:0006333 1 0.014
phosphorus metabolic process GO:0006793 232 0.014
cell cycle phase transition GO:0044770 19 0.014
digestive system development GO:0055123 122 0.013
regulation of mitotic sister chromatid segregation GO:0033047 16 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.013
single organism biosynthetic process GO:0044711 91 0.013
peptidyl serine modification GO:0018209 20 0.013
regulation of synapse assembly GO:0051963 2 0.013
cellular macromolecule localization GO:0070727 75 0.013
response to other organism GO:0051707 101 0.013
spindle localization GO:0051653 51 0.013
cellular amino acid metabolic process GO:0006520 15 0.013
synapse organization GO:0050808 24 0.013
lipid metabolic process GO:0006629 77 0.012
regulation of cytoplasmic transport GO:1903649 3 0.012
mrna processing GO:0006397 13 0.012
lipid biosynthetic process GO:0008610 28 0.012
pronuclear migration GO:0035046 51 0.012
establishment of spindle localization GO:0051293 51 0.012
chemosensory behavior GO:0007635 33 0.012
gene silencing by rna GO:0031047 143 0.012
response to biotic stimulus GO:0009607 101 0.012
somatic muscle development GO:0007525 1 0.012
metaphase plate congression GO:0051310 5 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
regulation of reproductive process GO:2000241 66 0.012
regulation of apoptotic signaling pathway GO:2001233 1 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
organic substance transport GO:0071702 113 0.012
peptidyl serine phosphorylation GO:0018105 20 0.012
negative regulation of cellular protein metabolic process GO:0032269 27 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
metaphase anaphase transition of cell cycle GO:0044784 15 0.011
negative regulation of response to stimulus GO:0048585 73 0.011
positive regulation of proteasomal protein catabolic process GO:1901800 1 0.011
carbohydrate derivative metabolic process GO:1901135 141 0.011
regulation of filopodium assembly GO:0051489 2 0.011
cell migration GO:0016477 306 0.011
cognition GO:0050890 27 0.011
cell projection morphogenesis GO:0048858 148 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.011
molting cycle GO:0042303 281 0.011
rna interference GO:0016246 137 0.010
negative regulation of rna metabolic process GO:0051253 53 0.010
posttranscriptional gene silencing GO:0016441 143 0.010
axis specification GO:0009798 23 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010
negative regulation of organelle organization GO:0010639 20 0.010
heterocycle catabolic process GO:0046700 119 0.010
phagocytosis GO:0006909 115 0.010
neuron apoptotic process GO:0051402 4 0.010
negative regulation of cell communication GO:0010648 61 0.010
regulation of translation GO:0006417 19 0.010

sun-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013
spinocerebellar degeneration DOID:2478 0 0.010
central nervous system disease DOID:331 0 0.010
neurodegenerative disease DOID:1289 0 0.010
nervous system disease DOID:863 0 0.010