Caenorhabditis elegans

144 known processes

ire-1 (CELE_C41C4.4)

Protein IRE-1

ire-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.887
embryo development GO:0009790 3052 0.754
regulation of metabolic process GO:0019222 478 0.503
organelle organization GO:0006996 783 0.495
Human
post embryonic development GO:0009791 2152 0.481
negative regulation of biological process GO:0048519 567 0.434
Human Mouse
protein complex subunit organization GO:0071822 280 0.420
locomotion GO:0040011 1634 0.360
transport GO:0006810 1093 0.328
positive regulation of cellular process GO:0048522 332 0.292
vesicle mediated transport GO:0016192 852 0.278
nucleobase containing compound metabolic process GO:0006139 406 0.272
cellular catabolic process GO:0044248 199 0.251
Human
regulation of macromolecule metabolic process GO:0060255 421 0.249
endocytosis GO:0006897 819 0.241
behavior GO:0007610 527 0.226
organ development GO:0048513 1102 0.223
regulation of cell cycle GO:0051726 194 0.213
Mouse
regulation of primary metabolic process GO:0080090 292 0.209
establishment of localization GO:0051234 1171 0.206
cellular response to stress GO:0033554 162 0.198
catabolic process GO:0009056 318 0.198
Human
positive regulation of cellular metabolic process GO:0031325 178 0.188
protein metabolic process GO:0019538 422 0.185
Human Mouse
macromolecular complex subunit organization GO:0043933 320 0.184
developmental growth GO:0048589 412 0.181
negative regulation of cellular process GO:0048523 239 0.179
Human Mouse
sex differentiation GO:0007548 909 0.175
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.175
positive regulation of developmental process GO:0051094 408 0.173
cellular protein complex assembly GO:0043623 178 0.173
regulation of nitrogen compound metabolic process GO:0051171 222 0.172
cellular protein modification process GO:0006464 207 0.171
Human Mouse
regulation of cellular biosynthetic process GO:0031326 189 0.166
single organism catabolic process GO:0044712 129 0.166
phosphorus metabolic process GO:0006793 232 0.162
Human Mouse
reproductive structure development GO:0048608 850 0.160
transcription dna templated GO:0006351 168 0.153
genitalia development GO:0048806 741 0.149
regulation of gene expression epigenetic GO:0040029 163 0.143
nucleic acid metabolic process GO:0090304 299 0.141
multi organism reproductive process GO:0044703 867 0.140
defense response GO:0006952 296 0.138
death GO:0016265 547 0.137
body morphogenesis GO:0010171 620 0.136
nervous system development GO:0007399 253 0.132
aging GO:0007568 812 0.131
rna metabolic process GO:0016070 228 0.131
neurogenesis GO:0022008 236 0.128
positive regulation of cellular biosynthetic process GO:0031328 109 0.126
cellular macromolecule biosynthetic process GO:0034645 247 0.125
macromolecule catabolic process GO:0009057 202 0.124
Human
positive regulation of multicellular organism growth GO:0040018 352 0.122
cellular component biogenesis GO:0044085 297 0.119
immune response GO:0006955 192 0.117
gene expression GO:0010467 412 0.115
reproductive system development GO:0061458 850 0.114
macromolecule modification GO:0043412 218 0.111
Human Mouse
macromolecule localization GO:0033036 771 0.110
negative regulation of gene expression GO:0010629 217 0.108
Human
organic substance biosynthetic process GO:1901576 323 0.106
phosphate containing compound metabolic process GO:0006796 232 0.105
Human Mouse
cell cycle process GO:0022402 482 0.105
Mouse
chromosome organization GO:0051276 104 0.104
Human
cell development GO:0048468 696 0.104
positive regulation of multicellular organismal process GO:0051240 417 0.104
cell type specific apoptotic process GO:0097285 4 0.103
response to chemical GO:0042221 356 0.100
single organism signaling GO:0044700 401 0.099
regulation of growth GO:0040008 409 0.099
response to external stimulus GO:0009605 289 0.098
regulation of multicellular organismal process GO:0051239 726 0.098
positive regulation of metabolic process GO:0009893 187 0.092
cellular nitrogen compound catabolic process GO:0044270 119 0.091
Human
biosynthetic process GO:0009058 323 0.090
determination of adult lifespan GO:0008340 812 0.089
actomyosin structure organization GO:0031032 154 0.088
gonad development GO:0008406 840 0.087
regulation of biological quality GO:0065008 741 0.087
single organism reproductive process GO:0044702 1196 0.086
growth GO:0040007 562 0.086
protein localization GO:0008104 205 0.084
hermaphrodite genitalia development GO:0040035 734 0.084
organic substance catabolic process GO:1901575 294 0.083
Human
cellular component morphogenesis GO:0032989 318 0.083
organelle assembly GO:0070925 214 0.082
protein complex assembly GO:0006461 186 0.080
posttranscriptional regulation of gene expression GO:0010608 166 0.080
lipid metabolic process GO:0006629 77 0.079
protein modification process GO:0036211 207 0.078
Human Mouse
multicellular organism reproduction GO:0032504 819 0.078
small molecule metabolic process GO:0044281 186 0.077
positive regulation of macromolecule metabolic process GO:0010604 149 0.077
positive regulation of developmental growth GO:0048639 354 0.076
macromolecular complex assembly GO:0065003 193 0.075
response to organic substance GO:0010033 131 0.075
regulation of cellular component organization GO:0051128 248 0.074
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.073
multicellular organismal aging GO:0010259 812 0.073
single organism localization GO:1902578 518 0.071
mitotic sister chromatid segregation GO:0000070 38 0.069
regulation of gene expression GO:0010468 366 0.069
single organism organelle organization GO:1902589 501 0.068
Human
lipid localization GO:0010876 573 0.067
protein complex biogenesis GO:0070271 186 0.065
gene silencing GO:0016458 143 0.065
positive regulation of biosynthetic process GO:0009891 109 0.065
aromatic compound catabolic process GO:0019439 116 0.064
Human
cell cycle GO:0007049 526 0.064
Mouse
aromatic compound biosynthetic process GO:0019438 192 0.064
regulation of protein metabolic process GO:0051246 81 0.063
receptor mediated endocytosis GO:0006898 715 0.062
cellular component assembly GO:0022607 293 0.061
regulation of cell differentiation GO:0045595 81 0.060
lipid storage GO:0019915 565 0.059
positive regulation of growth GO:0045927 369 0.058
anatomical structure formation involved in morphogenesis GO:0048646 250 0.057
maintenance of location GO:0051235 580 0.056
cellular protein metabolic process GO:0044267 279 0.056
Human Mouse
secretion by cell GO:0032940 138 0.055
development of primary sexual characteristics GO:0045137 840 0.054
myofibril assembly GO:0030239 154 0.054
multicellular organismal reproductive process GO:0048609 815 0.054
single organism transport GO:0044765 447 0.054
regulation of developmental process GO:0050793 684 0.053
cellular macromolecule catabolic process GO:0044265 73 0.052
Human
regulation of signaling GO:0023051 172 0.052
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.052
intracellular signal transduction GO:0035556 96 0.050
regulation of cellular metabolic process GO:0031323 305 0.050
negative regulation of developmental process GO:0051093 227 0.050
nucleobase containing compound catabolic process GO:0034655 114 0.049
Human
regulation of multicellular organismal development GO:2000026 317 0.049
generation of neurons GO:0048699 235 0.049
developmental process involved in reproduction GO:0003006 1165 0.049
multi organism reproductive behavior GO:0044705 387 0.049
cellular response to chemical stimulus GO:0070887 129 0.048
intracellular receptor signaling pathway GO:0030522 2 0.048
positive regulation of rna metabolic process GO:0051254 103 0.047
microtubule based process GO:0007017 182 0.046
carbohydrate derivative catabolic process GO:1901136 82 0.045
positive regulation of nucleic acid templated transcription GO:1903508 102 0.045
positive regulation of gene expression GO:0010628 112 0.045
membrane organization GO:0061024 135 0.045
striated muscle cell development GO:0055002 157 0.044
negative regulation of metabolic process GO:0009892 240 0.043
Human
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.043
programmed cell death GO:0012501 500 0.042
cellular biosynthetic process GO:0044249 315 0.042
striated muscle myosin thick filament assembly GO:0071688 138 0.042
cellular component assembly involved in morphogenesis GO:0010927 183 0.041
establishment of localization in cell GO:0051649 318 0.041
regulation of cell division GO:0051302 142 0.041
apoptotic process GO:0006915 478 0.041
regulation of developmental growth GO:0048638 389 0.041
multicellular organism growth GO:0035264 385 0.041
muscle structure development GO:0061061 191 0.040
regulation of multicellular organism growth GO:0040014 373 0.040
cellular localization GO:0051641 360 0.039
muscle cell differentiation GO:0042692 171 0.039
neuron development GO:0048666 199 0.039
regulation of macromolecule biosynthetic process GO:0010556 189 0.039
cell death GO:0008219 547 0.038
reproductive behavior GO:0019098 387 0.038
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.037
heterocycle catabolic process GO:0046700 119 0.037
Human
organonitrogen compound metabolic process GO:1901564 151 0.037
negative regulation of macromolecule metabolic process GO:0010605 229 0.037
Human
purine ribonucleoside metabolic process GO:0046128 92 0.037
regulation of cell communication GO:0010646 176 0.037
multicellular organismal reproductive behavior GO:0033057 384 0.036
purine nucleoside metabolic process GO:0042278 92 0.036
protein catabolic process GO:0030163 162 0.035
localization of cell GO:0051674 313 0.035
molting cycle GO:0042303 281 0.035
rna localization GO:0006403 3 0.035
myosin filament organization GO:0031033 138 0.035
nucleobase containing compound biosynthetic process GO:0034654 184 0.034
actin cytoskeleton organization GO:0030036 184 0.034
multi multicellular organism process GO:0044706 390 0.034
muscle cell development GO:0055001 158 0.034
gene silencing by rna GO:0031047 143 0.034
cytoskeleton organization GO:0007010 339 0.033
cellular macromolecular complex assembly GO:0034622 184 0.033
response to wounding GO:0009611 4 0.033
meiotic nuclear division GO:0007126 300 0.033
rna interference GO:0016246 137 0.033
response to abiotic stimulus GO:0009628 152 0.033
dna metabolic process GO:0006259 74 0.032
Human
modification dependent macromolecule catabolic process GO:0043632 32 0.032
regulation of cellular protein metabolic process GO:0032268 75 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.032
modification dependent protein catabolic process GO:0019941 32 0.031
regulation of biosynthetic process GO:0009889 189 0.031
organophosphate metabolic process GO:0019637 125 0.030
cellular component movement GO:0006928 388 0.030
myosin filament assembly GO:0031034 138 0.030
positive regulation of neurogenesis GO:0050769 4 0.030
response to external biotic stimulus GO:0043207 101 0.030
response to biotic stimulus GO:0009607 101 0.030
multi organism behavior GO:0051705 389 0.029
macromolecule biosynthetic process GO:0009059 250 0.029
ribonucleotide metabolic process GO:0009259 99 0.029
striated muscle cell differentiation GO:0051146 158 0.029
cell division GO:0051301 262 0.029
posttranscriptional gene silencing by rna GO:0035194 143 0.028
signal transduction GO:0007165 317 0.028
chromosome segregation GO:0007059 180 0.028
regulation of response to stimulus GO:0048583 243 0.028
intracellular transport GO:0046907 77 0.028
negative regulation of cellular metabolic process GO:0031324 95 0.028
Human
cellular lipid metabolic process GO:0044255 40 0.027
ubiquitin dependent protein catabolic process GO:0006511 32 0.027
response to other organism GO:0051707 101 0.027
neuron differentiation GO:0030182 217 0.026
cell migration GO:0016477 306 0.025
cell proliferation GO:0008283 116 0.025
negative regulation of response to stimulus GO:0048585 73 0.024
regulation of organelle organization GO:0033043 164 0.023
cell motility GO:0048870 313 0.023
purine nucleotide catabolic process GO:0006195 75 0.023
regulation of neurogenesis GO:0050767 40 0.023
organic cyclic compound catabolic process GO:1901361 119 0.023
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.023
regulation of localization GO:0032879 194 0.022
purine containing compound catabolic process GO:0072523 75 0.022
secretion GO:0046903 147 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.021
actin filament based process GO:0030029 191 0.021
nucleobase containing small molecule metabolic process GO:0055086 115 0.021
system process GO:0003008 136 0.021
ribonucleoside triphosphate metabolic process GO:0009199 87 0.020
spindle organization GO:0007051 92 0.020
meiotic cell cycle process GO:1903046 170 0.020
sister chromatid segregation GO:0000819 46 0.020
posttranscriptional gene silencing GO:0016441 143 0.020
mitotic cell cycle process GO:1903047 194 0.020
regulation of transcription dna templated GO:0006355 164 0.020
regulation of catabolic process GO:0009894 57 0.019
dauer larval development GO:0040024 92 0.019
regulation of cellular catabolic process GO:0031329 51 0.019
protein phosphorylation GO:0006468 85 0.019
Human Mouse
purine nucleoside triphosphate metabolic process GO:0009144 87 0.019
negative regulation of nucleic acid templated transcription GO:1903507 53 0.019
Human
defense response to other organism GO:0098542 100 0.019
negative regulation of cellular component organization GO:0051129 33 0.019
cell projection organization GO:0030030 231 0.019
meiotic chromosome segregation GO:0045132 139 0.018
membrane invagination GO:0010324 98 0.018
nucleoside phosphate catabolic process GO:1901292 77 0.018
dna repair GO:0006281 23 0.018
meiotic cell cycle GO:0051321 335 0.018
regulation of cell cycle process GO:0010564 145 0.018
positive regulation of protein metabolic process GO:0051247 45 0.017
signaling GO:0023052 401 0.017
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.017
cell morphogenesis GO:0000902 163 0.017
purine ribonucleoside catabolic process GO:0046130 75 0.017
organonitrogen compound catabolic process GO:1901565 90 0.017
single organism intracellular transport GO:1902582 70 0.017
regulation of rna metabolic process GO:0051252 173 0.017
regulation of rna biosynthetic process GO:2001141 165 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.016
negative regulation of rna biosynthetic process GO:1902679 53 0.016
Human
transcription from rna polymerase ii promoter GO:0006366 149 0.016
negative regulation of apoptotic process GO:0043066 17 0.016
organelle fission GO:0048285 363 0.016
cell part morphogenesis GO:0032990 152 0.016
carbohydrate derivative metabolic process GO:1901135 141 0.016
negative regulation of multicellular organismal process GO:0051241 236 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.016
rna catabolic process GO:0006401 21 0.015
Human
regulation of programmed cell death GO:0043067 50 0.015
nucleoside catabolic process GO:0009164 78 0.015
purine containing compound metabolic process GO:0072521 95 0.015
positive regulation of cell projection organization GO:0031346 4 0.015
ribonucleoside metabolic process GO:0009119 98 0.015
cellular nitrogen compound biosynthetic process GO:0044271 192 0.015
ribonucleoside catabolic process GO:0042454 77 0.015
negative regulation of signaling GO:0023057 61 0.015
regulation of cell death GO:0010941 65 0.015
regulation of protein import into nucleus GO:0042306 3 0.015
purine nucleotide metabolic process GO:0006163 95 0.014
dendrite development GO:0016358 42 0.014
response to bacterium GO:0009617 86 0.014
interspecies interaction between organisms GO:0044419 5 0.014
nucleotide catabolic process GO:0009166 77 0.014
oviposition GO:0018991 364 0.014
organic substance transport GO:0071702 113 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
single organism behavior GO:0044708 83 0.014
regulation of anatomical structure morphogenesis GO:0022603 51 0.014
regulation of signal transduction GO:0009966 135 0.014
neuron projection development GO:0031175 187 0.013
regulation of behavior GO:0050795 97 0.013
organophosphate catabolic process GO:0046434 81 0.013
regulation of nervous system development GO:0051960 41 0.013
axonal fasciculation GO:0007413 79 0.013
phosphorylation GO:0016310 116 0.013
Human Mouse
germ cell development GO:0007281 351 0.013
phagocytosis engulfment GO:0006911 98 0.013
negative regulation of rna metabolic process GO:0051253 53 0.013
Human
regulation of intracellular signal transduction GO:1902531 77 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
regulation of mitotic cell cycle GO:0007346 76 0.013
rna biosynthetic process GO:0032774 169 0.013
regulation of cell migration GO:0030334 55 0.012
cellular response to topologically incorrect protein GO:0035967 76 0.012
engulfment of apoptotic cell GO:0043652 94 0.012
regulation of protein targeting GO:1903533 3 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.012
Human
collagen and cuticulin based cuticle development GO:0040002 99 0.012
regulation of cell proliferation GO:0042127 105 0.012
small gtpase mediated signal transduction GO:0007264 32 0.012
phagocytosis GO:0006909 115 0.012
amine metabolic process GO:0009308 15 0.012
purine nucleoside triphosphate catabolic process GO:0009146 72 0.012
neuron recognition GO:0008038 83 0.012
cellular amine metabolic process GO:0044106 15 0.012
vulval development GO:0040025 333 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
apoptotic cell clearance GO:0043277 111 0.011
sex determination GO:0007530 60 0.011
glycosyl compound metabolic process GO:1901657 100 0.011
organic cyclic compound biosynthetic process GO:1901362 195 0.011
sexual reproduction GO:0019953 546 0.011
organic acid metabolic process GO:0006082 47 0.011
cellular response to organic substance GO:0071310 119 0.011
positive regulation of catalytic activity GO:0043085 59 0.011
negative regulation of post embryonic development GO:0048581 208 0.011
negative regulation of cell communication GO:0010648 61 0.010
glycosyl compound catabolic process GO:1901658 79 0.010
pigmentation GO:0043473 2 0.010
carboxylic acid metabolic process GO:0019752 34 0.010
head development GO:0060322 1 0.010
nucleotide metabolic process GO:0009117 108 0.010
response to mechanical stimulus GO:0009612 28 0.010
nucleoside triphosphate metabolic process GO:0009141 87 0.010
regulation of cellular component movement GO:0051270 62 0.010
post embryonic organ development GO:0048569 336 0.010

ire-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org