Caenorhabditis elegans

148 known processes

cdc-48.2 (CELE_C41C4.8)

Protein CDC-48.2

cdc-48.2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.785
embryo development ending in birth or egg hatching GO:0009792 2992 0.743
macromolecule catabolic process GO:0009057 202 0.550
centrosomal and pronuclear rotation GO:0035047 6 0.464
post embryonic development GO:0009791 2152 0.428
establishment of localization GO:0051234 1171 0.389
Human Yeast Rat
cellular macromolecule biosynthetic process GO:0034645 247 0.362
Human
gamete generation GO:0007276 461 0.315
organelle organization GO:0006996 783 0.310
locomotion GO:0040011 1634 0.309
cellular nitrogen compound biosynthetic process GO:0044271 192 0.299
Human
organic substance biosynthetic process GO:1901576 323 0.288
Human
single fertilization GO:0007338 61 0.259
apoptotic process GO:0006915 478 0.258
Mouse
sexual reproduction GO:0019953 546 0.255
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.225
multi organism reproductive process GO:0044703 867 0.225
aging GO:0007568 812 0.220
organelle fission GO:0048285 363 0.211
determination of adult lifespan GO:0008340 812 0.205
regulation of metabolic process GO:0019222 478 0.203
Human Yeast Zebrafish Mouse Rat
regulation of nucleic acid templated transcription GO:1903506 165 0.199
single organism reproductive process GO:0044702 1196 0.192
protein catabolic process GO:0030163 162 0.191
regulation of primary metabolic process GO:0080090 292 0.188
Human Yeast Zebrafish Mouse Rat
cell death GO:0008219 547 0.187
Mouse
cellular protein catabolic process GO:0044257 37 0.182
meiotic cell cycle process GO:1903046 170 0.179
multicellular organism reproduction GO:0032504 819 0.178
regulation of nitrogen compound metabolic process GO:0051171 222 0.172
cellular protein metabolic process GO:0044267 279 0.169
transcription dna templated GO:0006351 168 0.165
developmental process involved in reproduction GO:0003006 1165 0.163
death GO:0016265 547 0.161
Mouse
meiotic cell cycle GO:0051321 335 0.159
fertilization GO:0009566 63 0.155
programmed cell death GO:0012501 500 0.155
Mouse
macromolecule biosynthetic process GO:0009059 250 0.154
Human
macromolecule localization GO:0033036 771 0.153
Human Yeast
cell cycle process GO:0022402 482 0.150
Yeast
multicellular organismal reproductive process GO:0048609 815 0.150
single organism organelle organization GO:1902589 501 0.148
Yeast
multicellular organismal aging GO:0010259 812 0.144
regulation of gene expression GO:0010468 366 0.144
female gamete generation GO:0007292 254 0.144
germ cell development GO:0007281 351 0.141
protein targeting to mitochondrion GO:0006626 2 0.140
regulation of macromolecule metabolic process GO:0060255 421 0.127
Human Yeast Zebrafish Mouse Rat
pronuclear migration GO:0035046 51 0.122
macromolecular complex subunit organization GO:0043933 320 0.122
Human Yeast Rat
modification dependent macromolecule catabolic process GO:0043632 32 0.122
aromatic compound biosynthetic process GO:0019438 192 0.121
Human
gonad development GO:0008406 840 0.118
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.116
positive regulation of rna biosynthetic process GO:1902680 102 0.116
cellular catabolic process GO:0044248 199 0.111
gene expression GO:0010467 412 0.107
Mouse
meiotic nuclear division GO:0007126 300 0.105
nucleobase containing compound metabolic process GO:0006139 406 0.098
cellular response to unfolded protein GO:0034620 71 0.095
body morphogenesis GO:0010171 620 0.092
vesicle mediated transport GO:0016192 852 0.090
Rat
sex differentiation GO:0007548 909 0.089
cellular biosynthetic process GO:0044249 315 0.087
Human
oogenesis GO:0048477 229 0.083
hermaphrodite genitalia development GO:0040035 734 0.082
cellular component movement GO:0006928 388 0.081
cellular response to stress GO:0033554 162 0.081
transport GO:0006810 1093 0.079
Human Yeast Rat
growth GO:0040007 562 0.079
Worm
lipid localization GO:0010876 573 0.078
positive regulation of cellular metabolic process GO:0031325 178 0.077
Human Yeast Mouse Rat
maintenance of location GO:0051235 580 0.076
Yeast
heterocycle catabolic process GO:0046700 119 0.075
negative regulation of biological process GO:0048519 567 0.074
proteolysis GO:0006508 61 0.073
rna metabolic process GO:0016070 228 0.073
Yeast
positive regulation of metabolic process GO:0009893 187 0.073
Human Yeast Mouse Rat
organic substance catabolic process GO:1901575 294 0.071
development of primary sexual characteristics GO:0045137 840 0.070
regulation of cellular metabolic process GO:0031323 305 0.069
Human Yeast Zebrafish Mouse Rat
receptor mediated endocytosis GO:0006898 715 0.069
nucleic acid templated transcription GO:0097659 169 0.069
chromosome segregation GO:0007059 180 0.068
Yeast
response to endoplasmic reticulum stress GO:0034976 71 0.067
mitotic spindle organization GO:0007052 81 0.067
Yeast
positive regulation of multicellular organismal process GO:0051240 417 0.066
Worm
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.066
multicellular organismal reproductive behavior GO:0033057 384 0.064
negative regulation of gene expression GO:0010629 217 0.064
positive regulation of catalytic activity GO:0043085 59 0.064
Human Mouse
nucleobase containing compound biosynthetic process GO:0034654 184 0.063
Human
ubiquitin dependent protein catabolic process GO:0006511 32 0.063
negative regulation of cellular process GO:0048523 239 0.062
catabolic process GO:0009056 318 0.062
lipid storage GO:0019915 565 0.062
regulation of cellular biosynthetic process GO:0031326 189 0.060
single organism transport GO:0044765 447 0.060
Human Yeast Rat
regulation of biosynthetic process GO:0009889 189 0.059
regulation of biological quality GO:0065008 741 0.059
Yeast
organic cyclic compound biosynthetic process GO:1901362 195 0.059
Human
response to wounding GO:0009611 4 0.058
nucleus localization GO:0051647 55 0.058
cell migration GO:0016477 306 0.057
molting cycle GO:0042303 281 0.057
reproductive structure development GO:0048608 850 0.055
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.055
biosynthetic process GO:0009058 323 0.054
Human
cellular localization GO:0051641 360 0.054
Human Yeast Rat
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 20 0.054
positive regulation of molecular function GO:0044093 61 0.054
Human Mouse
cellular macromolecule catabolic process GO:0044265 73 0.054
cellular response to chemical stimulus GO:0070887 129 0.054
heterocycle biosynthetic process GO:0018130 187 0.053
Human
oviposition GO:0018991 364 0.052
cell motility GO:0048870 313 0.051
protein metabolic process GO:0019538 422 0.050
cellular response to topologically incorrect protein GO:0035967 76 0.050
spermatogenesis GO:0007283 41 0.048
protein complex biogenesis GO:0070271 186 0.048
Human Rat
ribonucleotide catabolic process GO:0009261 75 0.048
regulation of rna metabolic process GO:0051252 173 0.047
proteasome assembly GO:0043248 1 0.046
response to abiotic stimulus GO:0009628 152 0.046
genitalia development GO:0048806 741 0.046
positive regulation of cellular process GO:0048522 332 0.045
Human Yeast Mouse Rat
inductive cell migration GO:0040039 145 0.044
microtubule based process GO:0007017 182 0.043
Yeast
nucleic acid metabolic process GO:0090304 299 0.041
Human Yeast
regulation of multicellular organismal process GO:0051239 726 0.041
Worm
male gamete generation GO:0048232 41 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.040
modification dependent protein catabolic process GO:0019941 32 0.040
negative regulation of macromolecule metabolic process GO:0010605 229 0.040
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.040
multi organism reproductive behavior GO:0044705 387 0.039
regulation of transcription dna templated GO:0006355 164 0.039
positive regulation of developmental process GO:0051094 408 0.039
Worm
organ development GO:0048513 1102 0.039
regulation of cellular catabolic process GO:0031329 51 0.039
Human Zebrafish Rat
negative regulation of metabolic process GO:0009892 240 0.039
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.038
behavior GO:0007610 527 0.038
cytoskeleton organization GO:0007010 339 0.037
Yeast
intracellular protein transmembrane import GO:0044743 3 0.036
positive regulation of transcription dna templated GO:0045893 102 0.036
rna biosynthetic process GO:0032774 169 0.036
cellular protein modification process GO:0006464 207 0.035
Human Yeast Zebrafish
positive regulation of cellular protein catabolic process GO:1903364 3 0.035
Human Rat
protein modification by small protein conjugation or removal GO:0070647 40 0.035
Human Yeast Zebrafish
positive regulation of cellular catabolic process GO:0031331 35 0.035
Human Rat
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.035
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.035
mitotic nuclear division GO:0007067 89 0.034
Yeast
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.034
positive regulation of hydrolase activity GO:0051345 38 0.034
Human Mouse
meiotic chromosome segregation GO:0045132 139 0.033
ribonucleoprotein complex assembly GO:0022618 4 0.033
response to heat GO:0009408 50 0.032
intracellular protein transmembrane transport GO:0065002 4 0.032
response to external stimulus GO:0009605 289 0.031
Yeast
positive regulation of macromolecule metabolic process GO:0010604 149 0.031
Human Yeast Mouse Rat
organonitrogen compound metabolic process GO:1901564 151 0.031
protein transmembrane transport GO:0071806 4 0.031
regulation of growth GO:0040008 409 0.030
Worm
negative regulation of vulval development GO:0040027 206 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.030
regulation of macromolecule biosynthetic process GO:0010556 189 0.030
vulval development GO:0040025 333 0.029
endocytosis GO:0006897 819 0.029
response to topologically incorrect protein GO:0035966 82 0.029
glycosylation GO:0070085 20 0.029
Human
multi organism behavior GO:0051705 389 0.028
regulation of multicellular organism growth GO:0040014 373 0.028
Worm
neuron development GO:0048666 199 0.028
developmental growth GO:0048589 412 0.028
Worm
regulation of rna biosynthetic process GO:2001141 165 0.028
spindle organization GO:0007051 92 0.028
Yeast
oocyte construction GO:0007308 2 0.027
cell type specific apoptotic process GO:0097285 4 0.027
dna templated transcription elongation GO:0006354 1 0.027
transcription from rna polymerase ii promoter GO:0006366 149 0.026
proteasomal protein catabolic process GO:0010498 20 0.026
oocyte axis specification GO:0007309 2 0.026
regulation of catalytic activity GO:0050790 78 0.026
Human Yeast Mouse
negative regulation of nematode larval development GO:0061064 208 0.026
positive regulation of nucleic acid templated transcription GO:1903508 102 0.026
single organism catabolic process GO:0044712 129 0.026
establishment of protein localization to membrane GO:0090150 3 0.026
positive regulation of biosynthetic process GO:0009891 109 0.025
signaling GO:0023052 401 0.025
regulation of protein catabolic process GO:0042176 13 0.025
Human Zebrafish Rat
head development GO:0060322 1 0.025
protein complex assembly GO:0006461 186 0.025
Human Rat
defense response GO:0006952 296 0.025
establishment of localization in cell GO:0051649 318 0.025
Human Yeast Rat
negative regulation of cellular metabolic process GO:0031324 95 0.025
positive regulation of rna metabolic process GO:0051254 103 0.025
cell cycle GO:0007049 526 0.024
positive regulation of intracellular transport GO:0032388 2 0.024
single organism cellular localization GO:1902580 72 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.024
muscle tissue development GO:0060537 1 0.024
positive regulation of multicellular organism growth GO:0040018 352 0.024
Worm
protein complex subunit organization GO:0071822 280 0.024
Human Yeast Rat
protein localization to nucleus GO:0034504 11 0.024
Yeast
mitotic cell cycle process GO:1903047 194 0.024
Yeast
regulation of molecular function GO:0065009 89 0.024
Human Yeast Mouse
cellular protein complex assembly GO:0043623 178 0.023
intracellular transport GO:0046907 77 0.023
Human Yeast Rat
regulation of protein metabolic process GO:0051246 81 0.022
Human Yeast Zebrafish Mouse Rat
cellular macromolecular complex assembly GO:0034622 184 0.022
carbohydrate derivative metabolic process GO:1901135 141 0.022
cellular response to metal ion GO:0071248 3 0.022
Yeast
transmembrane transport GO:0055085 110 0.022
cell development GO:0048468 696 0.022
regulation of localization GO:0032879 194 0.022
Yeast
signal transduction GO:0007165 317 0.021
negative regulation of developmental process GO:0051093 227 0.021
reproductive behavior GO:0019098 387 0.021
protein modification process GO:0036211 207 0.020
Human Yeast Zebrafish
nuclear migration GO:0007097 54 0.020
nucleoside monophosphate metabolic process GO:0009123 46 0.020
phosphate containing compound metabolic process GO:0006796 232 0.020
positive regulation of developmental growth GO:0048639 354 0.020
Worm
er associated ubiquitin dependent protein catabolic process GO:0030433 6 0.019
macromolecular complex assembly GO:0065003 193 0.019
Human Rat
cellular macromolecule localization GO:0070727 75 0.019
Human Yeast
response to chemical GO:0042221 356 0.019
regulation of cell death GO:0010941 65 0.019
Mouse
regulation of protein localization GO:0032880 50 0.019
Yeast
small molecule metabolic process GO:0044281 186 0.019
localization of cell GO:0051674 313 0.019
regulation of apoptotic signaling pathway GO:2001233 1 0.019
protein ubiquitination GO:0016567 25 0.018
Human Yeast Zebrafish
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.018
regulation of cell cycle process GO:0010564 145 0.018
multicellular organism growth GO:0035264 385 0.018
Worm
neuron projection development GO:0031175 187 0.018
ribonucleoside triphosphate metabolic process GO:0009199 87 0.018
protein refolding GO:0042026 1 0.018
positive regulation of ligase activity GO:0051351 2 0.018
phagocytosis GO:0006909 115 0.018
nucleobase containing compound catabolic process GO:0034655 114 0.018
organic substance transport GO:0071702 113 0.018
Human Yeast
response to organic substance GO:0010033 131 0.017
single organism intracellular transport GO:1902582 70 0.017
Human Yeast Rat
phosphorus metabolic process GO:0006793 232 0.017
rna interference GO:0016246 137 0.017
aromatic compound catabolic process GO:0019439 116 0.016
positive regulation of proteasomal protein catabolic process GO:1901800 1 0.016
Human Rat
regulation of cell proliferation GO:0042127 105 0.016
organic cyclic compound catabolic process GO:1901361 119 0.016
organic acid metabolic process GO:0006082 47 0.016
nucleotide catabolic process GO:0009166 77 0.016
multi multicellular organism process GO:0044706 390 0.016
nucleoside phosphate catabolic process GO:1901292 77 0.016
protein localization to organelle GO:0033365 37 0.016
Yeast
regulation of gene expression epigenetic GO:0040029 163 0.016
macromolecule modification GO:0043412 218 0.016
Human Yeast Zebrafish
gene silencing GO:0016458 143 0.015
regulation of response to stimulus GO:0048583 243 0.015
single organism localization GO:1902578 518 0.015
Human Yeast Rat
regulation of cell cycle GO:0051726 194 0.015
membrane invagination GO:0010324 98 0.015
Yeast
cellular response to inorganic substance GO:0071241 3 0.015
Yeast
regulation of cellular protein metabolic process GO:0032268 75 0.015
Human Yeast Zebrafish Mouse Rat
immune response GO:0006955 192 0.015
generation of neurons GO:0048699 235 0.015
regulation of hydrolase activity GO:0051336 45 0.015
Human Mouse
ribonucleoside catabolic process GO:0042454 77 0.015
regulation of cellular component organization GO:0051128 248 0.015
Human Yeast
establishment of nucleus localization GO:0040023 55 0.015
membrane organization GO:0061024 135 0.014
Yeast
cellular response to organic substance GO:0071310 119 0.014
organelle localization GO:0051640 127 0.014
Yeast
cellular protein localization GO:0034613 75 0.014
Human Yeast
cellular component biogenesis GO:0044085 297 0.014
Human Mouse Rat
secretion by cell GO:0032940 138 0.014
positive regulation of growth GO:0045927 369 0.014
Worm
response to inorganic substance GO:0010035 50 0.014
Yeast
purine nucleotide metabolic process GO:0006163 95 0.013
endoplasmic reticulum unfolded protein response GO:0030968 66 0.013
purine nucleoside metabolic process GO:0042278 92 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 9 0.013
Human Yeast Zebrafish
nuclear pore organization GO:0006999 2 0.013
nucleoside catabolic process GO:0009164 78 0.013
regulation of developmental growth GO:0048638 389 0.013
Worm
intracellular receptor signaling pathway GO:0030522 2 0.013
positive regulation of intracellular protein transport GO:0090316 2 0.013
ribonucleoside monophosphate metabolic process GO:0009161 45 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
Yeast Zebrafish
cellular response to abiotic stimulus GO:0071214 4 0.013
cellular response to dna damage stimulus GO:0006974 41 0.013
Human
purine nucleoside monophosphate catabolic process GO:0009128 28 0.013
nucleoside triphosphate catabolic process GO:0009143 72 0.013
cell proliferation GO:0008283 116 0.013
regulation of cytoplasmic transport GO:1903649 3 0.013
posttranscriptional gene silencing GO:0016441 143 0.013
positive regulation of protein transport GO:0051222 4 0.012
organophosphate metabolic process GO:0019637 125 0.012
atp catabolic process GO:0006200 27 0.012
posttranscriptional gene silencing by rna GO:0035194 143 0.012
purine ribonucleotide metabolic process GO:0009150 95 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.012
autophagy GO:0006914 29 0.012
Yeast
hermaphrodite germ line sex determination GO:0040021 48 0.012
cellular component assembly GO:0022607 293 0.012
Human Mouse Rat
positive regulation of protein localization to nucleus GO:1900182 2 0.012
Yeast
negative regulation of response to stimulus GO:0048585 73 0.012
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.011
regulation of programmed cell death GO:0043067 50 0.011
Mouse
posttranscriptional regulation of gene expression GO:0010608 166 0.011
myosin filament assembly GO:0031034 138 0.011
protein localization GO:0008104 205 0.011
Human Yeast
regulation of phosphate metabolic process GO:0019220 81 0.011
dna templated transcription initiation GO:0006352 3 0.011
small gtpase mediated signal transduction GO:0007264 32 0.011
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.011
Human Rat
gene silencing by rna GO:0031047 143 0.011
regulation of post embryonic development GO:0048580 260 0.011
response to temperature stimulus GO:0009266 66 0.011
tissue development GO:0009888 112 0.011
glycosyl compound metabolic process GO:1901657 100 0.011
carboxylic acid metabolic process GO:0019752 34 0.011
purine containing compound metabolic process GO:0072521 95 0.011
establishment of protein localization to mitochondrion GO:0072655 2 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
regulation of signal transduction GO:0009966 135 0.011
purine nucleoside catabolic process GO:0006152 75 0.011
protein transport GO:0015031 45 0.011
Human Yeast
regulation of vulval development GO:0040028 248 0.011
muscle structure development GO:0061061 191 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.011
regulation of developmental process GO:0050793 684 0.011
Worm
striated muscle myosin thick filament assembly GO:0071688 138 0.011
sex determination GO:0007530 60 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 5 0.010
Human Zebrafish Rat
phosphorylation GO:0016310 116 0.010
positive regulation of gene expression GO:0010628 112 0.010
protein oligomerization GO:0051259 4 0.010
Rat
response to nutrient levels GO:0031667 35 0.010
Yeast
regulation of nucleocytoplasmic transport GO:0046822 3 0.010

cdc-48.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.052
Human
nervous system disease DOID:863 0 0.018
Human
neuromuscular disease DOID:440 0 0.014
charcot marie tooth disease type 2 DOID:0050539 0 0.014
charcot marie tooth disease DOID:10595 0 0.014
neuropathy DOID:870 0 0.014