Caenorhabditis elegans

67 known processes

spd-2 (CELE_F32H2.3)

Protein SPD-2

spd-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.864
embryo development ending in birth or egg hatching GO:0009792 2992 0.651
reproductive system development GO:0061458 850 0.629
cellular biosynthetic process GO:0044249 315 0.500
organ development GO:0048513 1102 0.498
cellular response to stress GO:0033554 162 0.417
single organism organelle organization GO:1902589 501 0.386
sex differentiation GO:0007548 909 0.378
organophosphate metabolic process GO:0019637 125 0.373
regulation of metabolic process GO:0019222 478 0.342
chromosome segregation GO:0007059 180 0.293
biosynthetic process GO:0009058 323 0.287
phosphate containing compound metabolic process GO:0006796 232 0.287
purine containing compound metabolic process GO:0072521 95 0.286
meiotic cell cycle process GO:1903046 170 0.281
nucleotide metabolic process GO:0009117 108 0.276
signaling GO:0023052 401 0.275
cell cycle process GO:0022402 482 0.267
aging GO:0007568 812 0.254
vesicle mediated transport GO:0016192 852 0.248
cell fate commitment GO:0045165 139 0.247
cellular component assembly GO:0022607 293 0.246
purine ribonucleotide metabolic process GO:0009150 95 0.234
phosphorus metabolic process GO:0006793 232 0.228
purine nucleotide catabolic process GO:0006195 75 0.215
endocytosis GO:0006897 819 0.212
locomotion GO:0040011 1634 0.210
organelle fission GO:0048285 363 0.208
organic substance biosynthetic process GO:1901576 323 0.207
cellular component biogenesis GO:0044085 297 0.204
establishment of localization GO:0051234 1171 0.204
cell migration GO:0016477 306 0.198
ribonucleotide metabolic process GO:0009259 99 0.198
determination of adult lifespan GO:0008340 812 0.198
cytoskeleton organization GO:0007010 339 0.194
regulation of biosynthetic process GO:0009889 189 0.190
small molecule metabolic process GO:0044281 186 0.182
meiotic nuclear division GO:0007126 300 0.180
nucleoside phosphate catabolic process GO:1901292 77 0.179
spindle organization GO:0007051 92 0.176
nucleobase containing small molecule metabolic process GO:0055086 115 0.176
multicellular organismal aging GO:0010259 812 0.174
nucleobase containing compound metabolic process GO:0006139 406 0.173
meiotic chromosome segregation GO:0045132 139 0.173
nucleobase containing compound biosynthetic process GO:0034654 184 0.171
genitalia development GO:0048806 741 0.171
regulation of response to stimulus GO:0048583 243 0.170
hermaphrodite genitalia development GO:0040035 734 0.167
ribonucleoside catabolic process GO:0042454 77 0.166
nucleoside catabolic process GO:0009164 78 0.161
cell surface receptor signaling pathway GO:0007166 149 0.158
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.154
regulation of primary metabolic process GO:0080090 292 0.153
purine nucleoside catabolic process GO:0006152 75 0.152
nuclear migration GO:0007097 54 0.151
regulation of organelle organization GO:0033043 164 0.149
nucleic acid metabolic process GO:0090304 299 0.147
purine nucleoside triphosphate metabolic process GO:0009144 87 0.143
reproductive structure development GO:0048608 850 0.143
ribonucleotide catabolic process GO:0009261 75 0.134
ribonucleoside triphosphate metabolic process GO:0009199 87 0.132
nucleoside triphosphate catabolic process GO:0009143 72 0.129
development of primary sexual characteristics GO:0045137 840 0.129
organelle organization GO:0006996 783 0.128
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.128
cell cycle GO:0007049 526 0.126
gonad development GO:0008406 840 0.124
macromolecular complex assembly GO:0065003 193 0.123
carbohydrate derivative catabolic process GO:1901136 82 0.122
regulation of nitrogen compound metabolic process GO:0051171 222 0.121
organophosphate catabolic process GO:0046434 81 0.121
transport GO:0006810 1093 0.120
positive regulation of cellular metabolic process GO:0031325 178 0.120
organonitrogen compound catabolic process GO:1901565 90 0.120
nucleoside triphosphate metabolic process GO:0009141 87 0.119
meiotic cell cycle GO:0051321 335 0.117
mitotic sister chromatid segregation GO:0000070 38 0.115
regulation of cellular metabolic process GO:0031323 305 0.115
regulation of cell cycle process GO:0010564 145 0.114
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.113
regulation of biological quality GO:0065008 741 0.110
signal transduction GO:0007165 317 0.110
tissue development GO:0009888 112 0.109
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.108
ribose phosphate metabolic process GO:0019693 99 0.108
developmental process involved in reproduction GO:0003006 1165 0.106
purine ribonucleoside catabolic process GO:0046130 75 0.106
negative regulation of metabolic process GO:0009892 240 0.105
receptor mediated endocytosis GO:0006898 715 0.104
mitotic cell cycle process GO:1903047 194 0.103
purine containing compound catabolic process GO:0072523 75 0.102
purine ribonucleoside metabolic process GO:0046128 92 0.100
meiosis i GO:0007127 19 0.100
cell division GO:0051301 262 0.100
single organism reproductive process GO:0044702 1196 0.096
purine nucleoside metabolic process GO:0042278 92 0.096
protein complex subunit organization GO:0071822 280 0.096
positive regulation of macromolecule metabolic process GO:0010604 149 0.093
ribonucleoside metabolic process GO:0009119 98 0.091
organelle localization GO:0051640 127 0.089
post embryonic development GO:0009791 2152 0.088
cellular macromolecule biosynthetic process GO:0034645 247 0.088
actin filament based process GO:0030029 191 0.087
guanosine containing compound catabolic process GO:1901069 48 0.085
lipid localization GO:0010876 573 0.084
single organism biosynthetic process GO:0044711 91 0.083
macromolecule biosynthetic process GO:0009059 250 0.083
maintenance of location GO:0051235 580 0.082
microtubule based process GO:0007017 182 0.082
nucleoside phosphate metabolic process GO:0006753 108 0.081
glycosyl compound metabolic process GO:1901657 100 0.081
nucleotide catabolic process GO:0009166 77 0.081
purine nucleotide metabolic process GO:0006163 95 0.081
cellular response to dna damage stimulus GO:0006974 41 0.078
macromolecule localization GO:0033036 771 0.077
cellular protein complex assembly GO:0043623 178 0.077
regulation of gene expression GO:0010468 366 0.076
lipid storage GO:0019915 565 0.075
dna repair GO:0006281 23 0.073
purine nucleoside triphosphate catabolic process GO:0009146 72 0.070
cellular localization GO:0051641 360 0.070
organic cyclic compound catabolic process GO:1901361 119 0.070
maintenance of protein location in cell GO:0032507 12 0.070
response to chemical GO:0042221 356 0.069
organic cyclic compound biosynthetic process GO:1901362 195 0.068
oviposition GO:0018991 364 0.067
protein complex biogenesis GO:0070271 186 0.065
glycosyl compound catabolic process GO:1901658 79 0.065
heterocycle biosynthetic process GO:0018130 187 0.064
nucleobase containing compound catabolic process GO:0034655 114 0.063
regulation of macromolecule biosynthetic process GO:0010556 189 0.062
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.062
multicellular organism growth GO:0035264 385 0.061
multi organism reproductive process GO:0044703 867 0.061
organonitrogen compound metabolic process GO:1901564 151 0.059
aromatic compound biosynthetic process GO:0019438 192 0.058
regulation of transcription dna templated GO:0006355 164 0.057
posttranscriptional regulation of gene expression GO:0010608 166 0.057
carbohydrate derivative metabolic process GO:1901135 141 0.056
single organism signaling GO:0044700 401 0.056
regulation of macromolecule metabolic process GO:0060255 421 0.055
aromatic compound catabolic process GO:0019439 116 0.054
cellular catabolic process GO:0044248 199 0.053
single organism localization GO:1902578 518 0.052
rna metabolic process GO:0016070 228 0.052
gene expression GO:0010467 412 0.052
chromosome organization involved in meiosis GO:0070192 25 0.051
body morphogenesis GO:0010171 620 0.049
regulation of cellular component organization GO:0051128 248 0.049
purine nucleoside monophosphate metabolic process GO:0009126 43 0.048
nucleoside monophosphate metabolic process GO:0009123 46 0.048
regulation of molecular function GO:0065009 89 0.047
cellular macromolecular complex assembly GO:0034622 184 0.047
dna metabolic process GO:0006259 74 0.047
female meiotic division GO:0007143 17 0.047
regulation of multicellular organism growth GO:0040014 373 0.047
regulation of vulval development GO:0040028 248 0.046
sister chromatid segregation GO:0000819 46 0.046
cellular component movement GO:0006928 388 0.046
purine ribonucleotide catabolic process GO:0009154 75 0.046
heterocycle catabolic process GO:0046700 119 0.045
single organism catabolic process GO:0044712 129 0.045
regulation of multicellular organismal development GO:2000026 317 0.044
regulation of nematode larval development GO:0061062 260 0.044
nucleoside metabolic process GO:0009116 99 0.044
regulation of protein localization GO:0032880 50 0.044
protein localization GO:0008104 205 0.044
cellular response to chemical stimulus GO:0070887 129 0.043
positive regulation of cellular biosynthetic process GO:0031328 109 0.043
establishment of organelle localization GO:0051656 123 0.043
pronuclear migration GO:0035046 51 0.042
regulation of catalytic activity GO:0050790 78 0.042
regulation of multicellular organismal process GO:0051239 726 0.042
cell death GO:0008219 547 0.041
membrane organization GO:0061024 135 0.041
death GO:0016265 547 0.040
sexual reproduction GO:0019953 546 0.040
multicellular organism reproduction GO:0032504 819 0.040
single organism transport GO:0044765 447 0.039
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.039
regulation of cell cycle GO:0051726 194 0.038
tissue morphogenesis GO:0048729 65 0.038
regulation of nucleic acid templated transcription GO:1903506 165 0.038
defense response GO:0006952 296 0.037
establishment of localization in cell GO:0051649 318 0.037
response to external stimulus GO:0009605 289 0.037
vulval development GO:0040025 333 0.037
posttranscriptional gene silencing GO:0016441 143 0.037
regulation of developmental process GO:0050793 684 0.036
dna recombination GO:0006310 19 0.036
ribonucleoside triphosphate catabolic process GO:0009203 72 0.036
post embryonic organ development GO:0048569 336 0.036
maintenance of protein location GO:0045185 15 0.035
regulation of rna metabolic process GO:0051252 173 0.035
regulation of growth GO:0040008 409 0.035
rna biosynthetic process GO:0032774 169 0.035
chromosome organization GO:0051276 104 0.034
synapsis GO:0007129 10 0.034
actin cytoskeleton organization GO:0030036 184 0.033
negative regulation of biological process GO:0048519 567 0.033
regulation of phosphorylation GO:0042325 45 0.033
negative regulation of gene expression GO:0010629 217 0.033
fertilization GO:0009566 63 0.033
small gtpase mediated signal transduction GO:0007264 32 0.033
negative regulation of cellular process GO:0048523 239 0.033
multi organism behavior GO:0051705 389 0.032
cell cycle g2 m phase transition GO:0044839 1 0.032
regulation of cell division GO:0051302 142 0.032
posttranscriptional gene silencing by rna GO:0035194 143 0.032
multicellular organismal reproductive process GO:0048609 815 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.031
oocyte differentiation GO:0009994 45 0.031
anatomical structure formation involved in morphogenesis GO:0048646 250 0.030
developmental growth GO:0048589 412 0.030
multicellular organismal reproductive behavior GO:0033057 384 0.030
catabolic process GO:0009056 318 0.030
mitotic nuclear division GO:0007067 89 0.030
regulation of post embryonic development GO:0048580 260 0.030
apoptotic process GO:0006915 478 0.029
organism emergence from protective structure GO:0071684 48 0.029
positive regulation of growth GO:0045927 369 0.029
cellular protein metabolic process GO:0044267 279 0.028
phosphorylation GO:0016310 116 0.028
cell motility GO:0048870 313 0.028
cellular nitrogen compound catabolic process GO:0044270 119 0.028
regulation of cellular biosynthetic process GO:0031326 189 0.028
response to organic substance GO:0010033 131 0.027
protein complex assembly GO:0006461 186 0.027
multi organism reproductive behavior GO:0044705 387 0.027
regulation of developmental growth GO:0048638 389 0.027
macromolecular complex subunit organization GO:0043933 320 0.027
gene silencing by rna GO:0031047 143 0.027
growth GO:0040007 562 0.026
cellular protein modification process GO:0006464 207 0.026
ribonucleoside monophosphate metabolic process GO:0009161 45 0.026
behavior GO:0007610 527 0.025
multi multicellular organism process GO:0044706 390 0.025
response to endoplasmic reticulum stress GO:0034976 71 0.025
maintenance of location in cell GO:0051651 12 0.025
localization of cell GO:0051674 313 0.025
regulation of meiotic cell cycle GO:0051445 136 0.025
positive regulation of developmental process GO:0051094 408 0.025
establishment of mitotic spindle orientation GO:0000132 28 0.025
guanosine containing compound metabolic process GO:1901068 49 0.024
endoplasmic reticulum unfolded protein response GO:0030968 66 0.024
regulation of phosphate metabolic process GO:0019220 81 0.024
mitotic spindle organization GO:0007052 81 0.024
establishment of spindle orientation GO:0051294 34 0.024
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.024
muscle structure development GO:0061061 191 0.023
programmed cell death GO:0012501 500 0.023
positive regulation of developmental growth GO:0048639 354 0.023
cellular response to inorganic substance GO:0071241 3 0.023
head development GO:0060322 1 0.023
macromolecule modification GO:0043412 218 0.023
negative regulation of biosynthetic process GO:0009890 65 0.023
response to temperature stimulus GO:0009266 66 0.023
establishment of nucleus localization GO:0040023 55 0.023
organic substance catabolic process GO:1901575 294 0.023
response to wounding GO:0009611 4 0.023
response to abiotic stimulus GO:0009628 152 0.022
positive regulation of multicellular organism growth GO:0040018 352 0.022
cell development GO:0048468 696 0.022
meiotic chromosome separation GO:0051307 5 0.022
atp metabolic process GO:0046034 42 0.021
positive regulation of multicellular organismal process GO:0051240 417 0.021
regulation of chromosome segregation GO:0051983 20 0.021
positive regulation of biosynthetic process GO:0009891 109 0.021
muscle tissue development GO:0060537 1 0.021
cell type specific apoptotic process GO:0097285 4 0.021
regulation of signaling GO:0023051 172 0.021
gtp catabolic process GO:0006184 46 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.020
regulation of signal transduction GO:0009966 135 0.020
gamete generation GO:0007276 461 0.020
atp catabolic process GO:0006200 27 0.020
regulation of nucleoside metabolic process GO:0009118 37 0.020
phagocytosis GO:0006909 115 0.019
purine nucleoside monophosphate catabolic process GO:0009128 28 0.019
protein oligomerization GO:0051259 4 0.019
regulation of rna biosynthetic process GO:2001141 165 0.019
regulation of meiosis GO:0040020 94 0.019
microtubule polymerization or depolymerization GO:0031109 22 0.019
spindle localization GO:0051653 51 0.019
regulation of mitotic cell cycle GO:0007346 76 0.019
ras protein signal transduction GO:0007265 31 0.019
regulation of purine nucleotide metabolic process GO:1900542 37 0.018
organic substance transport GO:0071702 113 0.018
regulation of phosphorus metabolic process GO:0051174 81 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 28 0.018
actomyosin structure organization GO:0031032 154 0.018
negative regulation of cellular biosynthetic process GO:0031327 65 0.018
secretion GO:0046903 147 0.018
reciprocal meiotic recombination GO:0007131 11 0.018
regulation of gene expression epigenetic GO:0040029 163 0.018
establishment of spindle localization GO:0051293 51 0.017
protein metabolic process GO:0019538 422 0.017
phagocytosis engulfment GO:0006911 98 0.017
single fertilization GO:0007338 61 0.017
reproductive behavior GO:0019098 387 0.017
system process GO:0003008 136 0.017
intracellular signal transduction GO:0035556 96 0.017
cellular ketone metabolic process GO:0042180 14 0.017
rna interference GO:0016246 137 0.017
inductive cell migration GO:0040039 145 0.016
cellular protein localization GO:0034613 75 0.016
establishment or maintenance of cell polarity GO:0007163 63 0.016
transcription dna templated GO:0006351 168 0.016
positive regulation of rna metabolic process GO:0051254 103 0.016
mitotic g2 m transition checkpoint GO:0044818 1 0.016
macromolecule catabolic process GO:0009057 202 0.016
positive regulation of post embryonic development GO:0048582 54 0.016
regulation of nuclear division GO:0051783 115 0.015
apoptotic cell clearance GO:0043277 111 0.015
regulation of dna catabolic process GO:1903624 1 0.015
positive regulation of metabolic process GO:0009893 187 0.015
gastrulation GO:0007369 58 0.015
axon development GO:0061564 163 0.015
carboxylic acid metabolic process GO:0019752 34 0.014
nucleic acid templated transcription GO:0097659 169 0.014
regulation of intracellular signal transduction GO:1902531 77 0.014
myofibril assembly GO:0030239 154 0.014
digestive system development GO:0055123 122 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.014
cellular macromolecule localization GO:0070727 75 0.014
organelle assembly GO:0070925 214 0.014
membrane invagination GO:0010324 98 0.014
establishment of mitotic spindle localization GO:0040001 41 0.014
cellular component morphogenesis GO:0032989 318 0.014
cellular nitrogen compound biosynthetic process GO:0044271 192 0.014
negative regulation of macromolecule metabolic process GO:0010605 229 0.014
protein modification process GO:0036211 207 0.014
taxis GO:0042330 128 0.014
positive regulation of gtpase activity GO:0043547 28 0.013
single organism cellular localization GO:1902580 72 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.013
germ cell development GO:0007281 351 0.013
nervous system development GO:0007399 253 0.013
cellular amine metabolic process GO:0044106 15 0.013
positive regulation of molecular function GO:0044093 61 0.013
defense response to bacterium GO:0042742 86 0.013
digestive tract morphogenesis GO:0048546 76 0.013
protein localization to organelle GO:0033365 37 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
embryonic morphogenesis GO:0048598 152 0.013
oogenesis GO:0048477 229 0.013
epithelium development GO:0060429 68 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.013
cell recognition GO:0008037 85 0.013
negative regulation of signal transduction GO:0009968 60 0.013
gtp metabolic process GO:0046039 46 0.012
response to heat GO:0009408 50 0.012
cellular response to organic substance GO:0071310 119 0.012
regulation of protein stability GO:0031647 3 0.012
wnt signaling pathway GO:0016055 27 0.012
regulation of cell communication GO:0010646 176 0.012
mitotic sister chromatid separation GO:0051306 13 0.012
nucleus localization GO:0051647 55 0.012
female gamete generation GO:0007292 254 0.012
cellular response to abiotic stimulus GO:0071214 4 0.012
dna duplex unwinding GO:0032508 3 0.011
tube development GO:0035295 126 0.011
ribonucleoside monophosphate catabolic process GO:0009158 28 0.011
regulation of cell death GO:0010941 65 0.011
assembly of actomyosin apparatus involved in cytokinesis GO:0000912 1 0.011
chemotaxis GO:0006935 120 0.011
cellular response to nitrogen compound GO:1901699 24 0.011
regulation of transferase activity GO:0051338 31 0.011
positive regulation of cellular process GO:0048522 332 0.011
collagen and cuticulin based cuticle development GO:0040002 99 0.011
rho protein signal transduction GO:0007266 2 0.011
negative regulation of cellular metabolic process GO:0031324 95 0.011
positive regulation of vulval development GO:0040026 52 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
epithelial tube morphogenesis GO:0060562 1 0.011
er nucleus signaling pathway GO:0006984 66 0.011
positive regulation of mitotic sister chromatid separation GO:1901970 1 0.011
regulation of gtpase activity GO:0043087 30 0.011
hatching GO:0035188 48 0.010
double strand break repair GO:0006302 5 0.010
gene silencing GO:0016458 143 0.010
regulation of localization GO:0032879 194 0.010
regulation of protein metabolic process GO:0051246 81 0.010
lipid metabolic process GO:0006629 77 0.010
protein transport GO:0015031 45 0.010
striated muscle cell development GO:0055002 157 0.010
axonal fasciculation GO:0007413 79 0.010
negative regulation of vulval development GO:0040027 206 0.010
organic acid metabolic process GO:0006082 47 0.010
enzyme linked receptor protein signaling pathway GO:0007167 50 0.010
positive regulation of catalytic activity GO:0043085 59 0.010
regulation of cell migration GO:0030334 55 0.010

spd-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
disease of cellular proliferation DOID:14566 0 0.013
cancer DOID:162 0 0.013
organ system benign neoplasm DOID:0060085 0 0.011
hair follicle neoplasm DOID:5375 0 0.011
benign neoplasm DOID:0060072 0 0.011
skin benign neoplasm DOID:3165 0 0.011
integumentary system benign neoplasm DOID:0060121 0 0.011
organ system cancer DOID:0050686 0 0.010