Caenorhabditis elegans

38 known processes

dlg-1 (CELE_C25F6.2)

Protein DLG-1

dlg-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organ development GO:0048513 1102 0.688
Mouse
protein metabolic process GO:0019538 422 0.594
Mouse
establishment of localization GO:0051234 1171 0.469
Human Mouse Rat Fly
cell development GO:0048468 696 0.442
Mouse Rat Fly
negative regulation of cellular process GO:0048523 239 0.360
Human Mouse Rat Fly
cell cycle process GO:0022402 482 0.330
Fly
embryo development GO:0009790 3052 0.308
endocytosis GO:0006897 819 0.307
Mouse Rat
single organism signaling GO:0044700 401 0.287
Mouse Rat Fly
multicellular organismal aging GO:0010259 812 0.286
determination of adult lifespan GO:0008340 812 0.280
cellular protein metabolic process GO:0044267 279 0.279
Mouse
phosphate containing compound metabolic process GO:0006796 232 0.259
Human Mouse
regulation of multicellular organismal process GO:0051239 726 0.256
Mouse Fly
receptor mediated endocytosis GO:0006898 715 0.255
Rat
regulation of developmental process GO:0050793 684 0.253
Mouse Fly
signal transduction GO:0007165 317 0.248
Mouse Rat Fly
embryo development ending in birth or egg hatching GO:0009792 2992 0.227
negative regulation of biological process GO:0048519 567 0.215
Human Mouse Rat Fly
regulation of response to stimulus GO:0048583 243 0.210
Mouse Rat Fly
vesicle mediated transport GO:0016192 852 0.206
Mouse Rat
organelle organization GO:0006996 783 0.196
Human Mouse Fly
neuron development GO:0048666 199 0.196
Mouse Rat
head development GO:0060322 1 0.190
Mouse
post embryonic development GO:0009791 2152 0.188
growth GO:0040007 562 0.187
Fly
nucleic acid metabolic process GO:0090304 299 0.182
Fly
transport GO:0006810 1093 0.180
Human Mouse Rat
macromolecule biosynthetic process GO:0009059 250 0.180
Fly
positive regulation of cell cycle GO:0045787 55 0.172
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.169
Fly
body morphogenesis GO:0010171 620 0.168
response to chemical GO:0042221 356 0.161
aging GO:0007568 812 0.157
neuron projection guidance GO:0097485 82 0.156
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.147
Mouse Rat
response to external stimulus GO:0009605 289 0.145
Fly
cellular component morphogenesis GO:0032989 318 0.138
Mouse Rat
developmental growth GO:0048589 412 0.136
Fly
macromolecule localization GO:0033036 771 0.133
Human Mouse Rat Fly
apoptotic process GO:0006915 478 0.132
regulation of multicellular organismal development GO:2000026 317 0.130
Mouse Fly
cellular nitrogen compound biosynthetic process GO:0044271 192 0.126
Fly
locomotion GO:0040011 1634 0.117
Fly
cell cycle GO:0007049 526 0.116
Human Fly
cell growth GO:0016049 44 0.116
cell morphogenesis GO:0000902 163 0.113
Mouse Rat
embryonic body morphogenesis GO:0010172 49 0.110
actin filament based process GO:0030029 191 0.109
Human Mouse
gene expression GO:0010467 412 0.104
Fly
cell surface receptor signaling pathway GO:0007166 149 0.103
Rat Fly
single organism transport GO:0044765 447 0.103
Human Mouse Rat
positive regulation of locomotion GO:0040017 42 0.100
regulation of biological quality GO:0065008 741 0.099
Human Mouse Rat Fly
regulation of cell size GO:0008361 30 0.098
regulation of transcription dna templated GO:0006355 164 0.097
Fly
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.097
regulation of primary metabolic process GO:0080090 292 0.096
Mouse Fly
chemotaxis GO:0006935 120 0.094
biosynthetic process GO:0009058 323 0.094
Fly
negative regulation of vulval development GO:0040027 206 0.093
genitalia development GO:0048806 741 0.093
regulation of anatomical structure size GO:0090066 46 0.093
Mouse
regulation of cell communication GO:0010646 176 0.091
Mouse Rat Fly
cellular protein modification process GO:0006464 207 0.088
Mouse
phosphorylation GO:0016310 116 0.087
Mouse
programmed cell death GO:0012501 500 0.086
cell motility GO:0048870 313 0.086
regulation of signal transduction GO:0009966 135 0.084
Mouse Rat Fly
rna metabolic process GO:0016070 228 0.083
Fly
cellular biosynthetic process GO:0044249 315 0.083
Fly
cellular component movement GO:0006928 388 0.083
nucleobase containing compound metabolic process GO:0006139 406 0.083
Fly
signaling GO:0023052 401 0.083
Mouse Rat Fly
axonogenesis GO:0007409 102 0.082
defense response GO:0006952 296 0.081
establishment of localization in cell GO:0051649 318 0.080
Mouse Fly
regulation of macromolecule metabolic process GO:0060255 421 0.079
Mouse Rat Fly
regulation of growth GO:0040008 409 0.079
Fly
multi organism reproductive process GO:0044703 867 0.078
regulation of cellular biosynthetic process GO:0031326 189 0.077
Fly
regulation of cellular component size GO:0032535 40 0.074
Mouse
organ morphogenesis GO:0009887 67 0.072
Mouse
behavior GO:0007610 527 0.072
Mouse Fly
oviposition GO:0018991 364 0.072
regulation of cell morphogenesis GO:0022604 40 0.072
regulation of anatomical structure morphogenesis GO:0022603 51 0.072
regulation of signaling GO:0023051 172 0.071
Mouse Rat Fly
multicellular organismal reproductive process GO:0048609 815 0.070
regulation of cellular metabolic process GO:0031323 305 0.070
Human Mouse Rat Fly
multi multicellular organism process GO:0044706 390 0.069
Fly
multicellular organism reproduction GO:0032504 819 0.069
cellular localization GO:0051641 360 0.068
Human Mouse Rat Fly
cellular macromolecule biosynthetic process GO:0034645 247 0.068
Fly
regulation of intracellular signal transduction GO:1902531 77 0.068
Mouse Fly
negative regulation of nematode larval development GO:0061064 208 0.067
taxis GO:0042330 128 0.066
Fly
aromatic compound biosynthetic process GO:0019438 192 0.066
Fly
lipid storage GO:0019915 565 0.066
negative regulation of post embryonic development GO:0048581 208 0.065
lipid localization GO:0010876 573 0.065
positive regulation of developmental process GO:0051094 408 0.064
Fly
protein modification process GO:0036211 207 0.064
Mouse
positive regulation of multicellular organismal process GO:0051240 417 0.063
Fly
maintenance of location GO:0051235 580 0.063
molting cycle GO:0042303 281 0.062
organic cyclic compound biosynthetic process GO:1901362 195 0.062
Fly
negative regulation of developmental process GO:0051093 227 0.061
posttranscriptional regulation of gene expression GO:0010608 166 0.059
regulation of developmental growth GO:0048638 389 0.059
Fly
cellular component biogenesis GO:0044085 297 0.058
regulation of locomotion GO:0040012 161 0.058
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.057
Fly
nucleus localization GO:0051647 55 0.056
negative regulation of bmp signaling pathway GO:0030514 1 0.056
cell cell signaling GO:0007267 118 0.055
Mouse Rat Fly
regulation of biosynthetic process GO:0009889 189 0.054
Fly
macromolecular complex subunit organization GO:0043933 320 0.053
Human Mouse
multi organism reproductive behavior GO:0044705 387 0.053
Fly
positive regulation of macromolecule metabolic process GO:0010604 149 0.053
Mouse
regulation of cellular component organization GO:0051128 248 0.051
Human Mouse Rat Fly
female gamete generation GO:0007292 254 0.051
regulation of nitrogen compound metabolic process GO:0051171 222 0.050
Fly
regulation of localization GO:0032879 194 0.049
Human Rat
death GO:0016265 547 0.049
cellular component assembly GO:0022607 293 0.048
positive regulation of cell communication GO:0010647 69 0.047
Rat
nucleic acid templated transcription GO:0097659 169 0.047
Fly
vulval development GO:0040025 333 0.047
regulation of multicellular organism growth GO:0040014 373 0.047
negative regulation of signaling GO:0023057 61 0.047
Mouse
gamete generation GO:0007276 461 0.047
secretion by cell GO:0032940 138 0.047
positive regulation of response to stimulus GO:0048584 55 0.046
axon guidance GO:0007411 82 0.046
establishment of nucleus localization GO:0040023 55 0.045
intracellular signal transduction GO:0035556 96 0.044
Mouse Fly
cell migration GO:0016477 306 0.044
organic substance biosynthetic process GO:1901576 323 0.044
Fly
regulation of mitotic cell cycle GO:0007346 76 0.043
Human
axon development GO:0061564 163 0.042
positive regulation of neurogenesis GO:0050769 4 0.042
regulation of gene expression GO:0010468 366 0.042
Fly
heterocycle biosynthetic process GO:0018130 187 0.042
Fly
regulation of metabolic process GO:0019222 478 0.041
Human Mouse Rat Fly
neuron projection development GO:0031175 187 0.041
Mouse Rat
negative regulation of macromolecule metabolic process GO:0010605 229 0.041
Rat Fly
single organism behavior GO:0044708 83 0.041
Mouse Fly
positive regulation of developmental growth GO:0048639 354 0.041
Fly
positive regulation of multicellular organism growth GO:0040018 352 0.041
reproductive structure development GO:0048608 850 0.040
Mouse
transcription dna templated GO:0006351 168 0.040
Fly
secretion GO:0046903 147 0.040
positive regulation of cellular process GO:0048522 332 0.039
Mouse Rat Fly
positive regulation of growth GO:0045927 369 0.039
Fly
translational initiation GO:0006413 2 0.038
muscle structure development GO:0061061 191 0.038
regulation of axon extension GO:0030516 20 0.037
ovulation GO:0030728 33 0.037
nervous system development GO:0007399 253 0.037
Mouse Rat Fly
negative regulation of cell cycle GO:0045786 53 0.037
Human
actin cytoskeleton organization GO:0030036 184 0.037
Human Mouse
protein complex subunit organization GO:0071822 280 0.036
Human Mouse
multicellular organism growth GO:0035264 385 0.036
regulation of translation GO:0006417 19 0.036
cell death GO:0008219 547 0.036
positive regulation of metabolic process GO:0009893 187 0.036
Mouse
multicellular organismal reproductive behavior GO:0033057 384 0.036
Fly
regulation of molecular function GO:0065009 89 0.035
Human Mouse Rat
reproductive system development GO:0061458 850 0.035
Mouse
negative regulation of multicellular organismal process GO:0051241 236 0.035
cell projection organization GO:0030030 231 0.035
Mouse Rat
neuron projection extension GO:1990138 37 0.035
embryonic morphogenesis GO:0048598 152 0.035
Mouse
regulation of actin filament based process GO:0032970 22 0.034
Mouse
negative regulation of cellular metabolic process GO:0031324 95 0.034
Human Rat Fly
muscle cell differentiation GO:0042692 171 0.033
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.033
muscle tissue development GO:0060537 1 0.033
Mouse
striated muscle cell differentiation GO:0051146 158 0.033
biological adhesion GO:0022610 21 0.033
Human Rat
lamellipodium organization GO:0097581 2 0.032
negative regulation of signal transduction GO:0009968 60 0.032
Mouse
carbohydrate derivative metabolic process GO:1901135 141 0.032
single organism organelle organization GO:1902589 501 0.032
Human Mouse Fly
positive regulation of stress activated mapk cascade GO:0032874 3 0.032
system process GO:0003008 136 0.032
Mouse
positive regulation of cell projection organization GO:0031346 4 0.031
gonad development GO:0008406 840 0.031
regulation of vulval development GO:0040028 248 0.031
regulation of neuron differentiation GO:0045664 40 0.031
sensory organ morphogenesis GO:0090596 2 0.031
response to abiotic stimulus GO:0009628 152 0.031
Fly
negative regulation of biosynthetic process GO:0009890 65 0.030
Fly
reproductive behavior GO:0019098 387 0.029
Fly
macromolecule catabolic process GO:0009057 202 0.029
tissue development GO:0009888 112 0.029
Mouse Fly
muscle cell development GO:0055001 158 0.029
organic substance catabolic process GO:1901575 294 0.029
regulation of rna biosynthetic process GO:2001141 165 0.029
Fly
single organism localization GO:1902578 518 0.029
Human Mouse Rat Fly
cell recognition GO:0008037 85 0.029
Mouse
protein phosphorylation GO:0006468 85 0.029
Mouse
nucleobase containing compound catabolic process GO:0034655 114 0.028
striated muscle cell development GO:0055002 157 0.028
neuron recognition GO:0008038 83 0.028
negative regulation of gene expression GO:0010629 217 0.027
Fly
developmental process involved in reproduction GO:0003006 1165 0.027
Mouse Fly
macromolecular complex assembly GO:0065003 193 0.027
Human Mouse
positive regulation of signal transduction GO:0009967 40 0.027
regulation of neuron projection development GO:0010975 31 0.027
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.026
Fly
negative regulation of cellular protein metabolic process GO:0032269 27 0.026
localization of cell GO:0051674 313 0.025
nitrogen compound transport GO:0071705 49 0.025
macromolecule modification GO:0043412 218 0.025
Mouse
sexual reproduction GO:0019953 546 0.025
single organism reproductive process GO:0044702 1196 0.025
adult behavior GO:0030534 3 0.025
sex differentiation GO:0007548 909 0.024
gene silencing GO:0016458 143 0.024
regulation of organelle organization GO:0033043 164 0.024
Mouse
transcription from rna polymerase ii promoter GO:0006366 149 0.024
Fly
regulation of rna metabolic process GO:0051252 173 0.024
Fly
ectoderm development GO:0007398 3 0.024
apical junction assembly GO:0043297 1 0.024
developmental growth involved in morphogenesis GO:0060560 37 0.024
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.024
regulation of nervous system development GO:0051960 41 0.023
Mouse Fly
cellular macromolecule catabolic process GO:0044265 73 0.023
negative regulation of cellular biosynthetic process GO:0031327 65 0.023
Fly
regulation of nematode larval development GO:0061062 260 0.023
positive regulation of signaling GO:0023056 66 0.023
Rat
regulation of phosphorus metabolic process GO:0051174 81 0.023
Human Mouse
response to biotic stimulus GO:0009607 101 0.023
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.023
positive regulation of cellular metabolic process GO:0031325 178 0.022
Mouse
neurogenesis GO:0022008 236 0.022
Mouse Rat
positive regulation of neuron projection development GO:0010976 4 0.022
small molecule metabolic process GO:0044281 186 0.021
myosin filament assembly GO:0031034 138 0.021
purine containing compound metabolic process GO:0072521 95 0.021
protein catabolic process GO:0030163 162 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.021
Fly
regulation of cellular protein metabolic process GO:0032268 75 0.021
Mouse
cellular nitrogen compound catabolic process GO:0044270 119 0.021
catabolic process GO:0009056 318 0.020
pattern specification process GO:0007389 59 0.020
Fly
multi organism behavior GO:0051705 389 0.020
Mouse Fly
dendrite development GO:0016358 42 0.020
Mouse Rat
immune response GO:0006955 192 0.020
Mouse
regulation of catalytic activity GO:0050790 78 0.020
Human Mouse
regulation of cell fate commitment GO:0010453 22 0.020
regulation of kinase activity GO:0043549 29 0.019
Mouse
cellular protein complex assembly GO:0043623 178 0.019
Mouse
regulation of apoptotic signaling pathway GO:2001233 1 0.019
cytokinesis GO:0000910 80 0.019
digestive tract development GO:0048565 122 0.018
regulation of bmp signaling pathway GO:0030510 3 0.018
regulation of nucleic acid templated transcription GO:1903506 165 0.018
Fly
post embryonic organ development GO:0048569 336 0.018
myosin filament organization GO:0031033 138 0.018
defense response to gram negative bacterium GO:0050829 64 0.018
regulation of phosphate metabolic process GO:0019220 81 0.018
Human Mouse
adult locomotory behavior GO:0008344 1 0.018
nuclear migration GO:0007097 54 0.018
regulation of protein metabolic process GO:0051246 81 0.018
Mouse
negative regulation of mitotic cell cycle GO:0045930 42 0.017
Human
positive regulation of phosphorus metabolic process GO:0010562 56 0.017
Mouse
tissue morphogenesis GO:0048729 65 0.017
Mouse Fly
meiotic cell cycle process GO:1903046 170 0.017
cellular catabolic process GO:0044248 199 0.017
regulation of meiotic cell cycle GO:0051445 136 0.017
single organism membrane organization GO:0044802 35 0.017
Human Mouse Rat
regulation of cell cycle GO:0051726 194 0.017
Human
chromatin remodeling GO:0006338 2 0.017
rna localization GO:0006403 3 0.017
meiotic cell cycle GO:0051321 335 0.017
regulation of cell cycle process GO:0010564 145 0.017
regulation of extent of cell growth GO:0061387 20 0.017
cell projection morphogenesis GO:0048858 148 0.017
Mouse Rat
negative regulation of response to stimulus GO:0048585 73 0.016
Mouse
skeletal muscle organ development GO:0060538 3 0.016
organic cyclic compound catabolic process GO:1901361 119 0.016
cellular component assembly involved in morphogenesis GO:0010927 183 0.016
canonical wnt signaling pathway GO:0060070 3 0.016
wnt signaling pathway GO:0016055 27 0.016
defense response to other organism GO:0098542 100 0.016
negative regulation of metabolic process GO:0009892 240 0.016
Human Rat Fly
regulation of cell proliferation GO:0042127 105 0.016
Mouse
cytoskeleton organization GO:0007010 339 0.015
Human Mouse Fly
hermaphrodite genitalia development GO:0040035 734 0.015
protein complex biogenesis GO:0070271 186 0.015
Human Mouse
epithelium development GO:0060429 68 0.015
Mouse Fly
phosphorus metabolic process GO:0006793 232 0.015
Human Mouse
filopodium assembly GO:0046847 2 0.015
cellular macromolecule localization GO:0070727 75 0.015
Human Rat
cellular response to stress GO:0033554 162 0.015
positive regulation of jnk cascade GO:0046330 3 0.015
protein localization to membrane GO:0072657 11 0.015
Human Rat
organelle fission GO:0048285 363 0.015
establishment of rna localization GO:0051236 3 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.015
Fly
mrna catabolic process GO:0006402 16 0.015
cell proliferation GO:0008283 116 0.014
Human Mouse
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 35 0.014
chromosome organization GO:0051276 104 0.014
cognition GO:0050890 27 0.014
organelle localization GO:0051640 127 0.014
Mouse Fly
mitotic cell cycle process GO:1903047 194 0.014
Fly
actomyosin structure organization GO:0031032 154 0.014
regulation of phosphorylation GO:0042325 45 0.014
Mouse
positive regulation of meiotic cell cycle GO:0051446 47 0.014
male sex differentiation GO:0046661 86 0.013
negative regulation of translational initiation GO:0045947 2 0.013
striated muscle myosin thick filament assembly GO:0071688 138 0.013
cellular macromolecular complex assembly GO:0034622 184 0.013
Mouse
response to other organism GO:0051707 101 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
synaptic transmission GO:0007268 106 0.013
Mouse Rat Fly
rna interference GO:0016246 137 0.013
heterocycle catabolic process GO:0046700 119 0.013
regulation of protein stability GO:0031647 3 0.013
negative regulation of cell communication GO:0010648 61 0.013
Mouse
negative regulation of neurogenesis GO:0050768 4 0.013
organic acid metabolic process GO:0006082 47 0.013
glycosyl compound metabolic process GO:1901657 100 0.013
defense response to bacterium GO:0042742 86 0.013
regulation of neurogenesis GO:0050767 40 0.013
protein complex assembly GO:0006461 186 0.013
Human Mouse
neuron differentiation GO:0030182 217 0.013
Mouse Rat
generation of neurons GO:0048699 235 0.013
Mouse Rat
response to external biotic stimulus GO:0043207 101 0.012
inductive cell migration GO:0040039 145 0.012
establishment or maintenance of cell polarity GO:0007163 63 0.012
Mouse Fly
negative regulation of rna metabolic process GO:0051253 53 0.012
Fly
neuromuscular process GO:0050905 1 0.012
Mouse
regulation of cell death GO:0010941 65 0.012
protein localization GO:0008104 205 0.012
Human Mouse Rat Fly
positive regulation of nucleic acid templated transcription GO:1903508 102 0.011
ribonucleoside triphosphate metabolic process GO:0009199 87 0.011
organonitrogen compound metabolic process GO:1901564 151 0.011
purine nucleotide metabolic process GO:0006163 95 0.011
nucleobase containing compound biosynthetic process GO:0034654 184 0.011
Fly
tube development GO:0035295 126 0.011
Mouse
regulation of cell development GO:0060284 49 0.011
regulation of cytoskeleton organization GO:0051493 41 0.011
Mouse
regulation of protein modification process GO:0031399 46 0.011
Mouse
positive regulation of organ growth GO:0046622 4 0.011
cell junction organization GO:0034330 18 0.011
axon cargo transport GO:0008088 7 0.011
rna biosynthetic process GO:0032774 169 0.011
Fly
mitotic nuclear division GO:0007067 89 0.011
myofibril assembly GO:0030239 154 0.010
actin filament bundle assembly GO:0051017 3 0.010
regulation of cell cell adhesion GO:0022407 1 0.010
oogenesis GO:0048477 229 0.010
Fly
response to bacterium GO:0009617 86 0.010
regulation of epithelial cell proliferation GO:0050678 1 0.010
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.010

dlg-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
epilepsy syndrome DOID:1826 0 0.016
central nervous system disease DOID:331 0 0.016
brain disease DOID:936 0 0.016
electroclinical syndrome DOID:0050701 0 0.016
neonatal period electroclinical syndrome DOID:0050702 0 0.016
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016