Caenorhabditis elegans

49 known processes

cki-2 (CELE_T05A6.2)

Protein CKI-2

cki-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.877
positive regulation of cellular process GO:0048522 332 0.828
Worm
organelle organization GO:0006996 783 0.707
single organism signaling GO:0044700 401 0.577
signal transduction GO:0007165 317 0.565
response to chemical GO:0042221 356 0.516
post embryonic development GO:0009791 2152 0.483
single organism organelle organization GO:1902589 501 0.468
organ development GO:0048513 1102 0.461
negative regulation of biological process GO:0048519 567 0.423
establishment of localization GO:0051234 1171 0.343
single organism localization GO:1902578 518 0.341
catabolic process GO:0009056 318 0.335
locomotion GO:0040011 1634 0.321
Worm
cellular catabolic process GO:0044248 199 0.310
organic substance catabolic process GO:1901575 294 0.292
cell cycle process GO:0022402 482 0.281
axonogenesis GO:0007409 102 0.277
regulation of cellular metabolic process GO:0031323 305 0.264
cellular protein metabolic process GO:0044267 279 0.251
cellular component movement GO:0006928 388 0.242
positive regulation of response to stimulus GO:0048584 55 0.238
developmental process involved in reproduction GO:0003006 1165 0.235
Worm
regulation of metabolic process GO:0019222 478 0.234
positive regulation of cellular metabolic process GO:0031325 178 0.228
phosphorus metabolic process GO:0006793 232 0.221
nucleobase containing compound metabolic process GO:0006139 406 0.213
signaling GO:0023052 401 0.208
regulation of developmental process GO:0050793 684 0.198
protein modification process GO:0036211 207 0.197
neurogenesis GO:0022008 236 0.196
behavior GO:0007610 527 0.195
Worm
macromolecular complex subunit organization GO:0043933 320 0.192
transport GO:0006810 1093 0.185
axon development GO:0061564 163 0.174
cell migration GO:0016477 306 0.169
phosphate containing compound metabolic process GO:0006796 232 0.165
regulation of primary metabolic process GO:0080090 292 0.164
localization of cell GO:0051674 313 0.159
wnt signaling pathway GO:0016055 27 0.159
organelle localization GO:0051640 127 0.153
canonical wnt signaling pathway GO:0060070 3 0.153
organelle assembly GO:0070925 214 0.151
meiotic cell cycle GO:0051321 335 0.150
Worm
protein metabolic process GO:0019538 422 0.140
macromolecule modification GO:0043412 218 0.137
cellular protein modification process GO:0006464 207 0.135
cell fate commitment GO:0045165 139 0.135
cell death GO:0008219 547 0.133
regulation of catabolic process GO:0009894 57 0.133
protein complex subunit organization GO:0071822 280 0.130
regulation of signal transduction GO:0009966 135 0.130
growth GO:0040007 562 0.129
regulation of signaling GO:0023051 172 0.124
apoptotic process GO:0006915 478 0.123
cell development GO:0048468 696 0.123
body morphogenesis GO:0010171 620 0.122
Worm
neuron projection morphogenesis GO:0048812 114 0.122
regulation of cell communication GO:0010646 176 0.121
organic cyclic compound catabolic process GO:1901361 119 0.119
meiotic nuclear division GO:0007126 300 0.115
Worm
cell adhesion GO:0007155 21 0.115
nucleic acid metabolic process GO:0090304 299 0.114
macromolecule localization GO:0033036 771 0.114
embryo development GO:0009790 3052 0.112
regulation of organ morphogenesis GO:2000027 4 0.111
death GO:0016265 547 0.111
positive regulation of developmental process GO:0051094 408 0.110
regulation of biological quality GO:0065008 741 0.109
microtubule based process GO:0007017 182 0.105
multi organism reproductive process GO:0044703 867 0.104
Worm
neuron differentiation GO:0030182 217 0.103
cellular nitrogen compound catabolic process GO:0044270 119 0.103
cellular response to stress GO:0033554 162 0.101
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.100
regulation of localization GO:0032879 194 0.100
organelle fission GO:0048285 363 0.100
neuron projection guidance GO:0097485 82 0.097
cell motility GO:0048870 313 0.097
regulation of response to stimulus GO:0048583 243 0.095
regulation of protein metabolic process GO:0051246 81 0.095
programmed cell death GO:0012501 500 0.094
digestive tract development GO:0048565 122 0.094
regulation of phosphate metabolic process GO:0019220 81 0.094
macromolecule catabolic process GO:0009057 202 0.093
negative regulation of multicellular organismal process GO:0051241 236 0.093
establishment of organelle localization GO:0051656 123 0.091
tissue development GO:0009888 112 0.089
mapk cascade GO:0000165 31 0.089
positive regulation of metabolic process GO:0009893 187 0.088
regulation of macromolecule metabolic process GO:0060255 421 0.087
head development GO:0060322 1 0.086
protein catabolic process GO:0030163 162 0.086
negative regulation of developmental process GO:0051093 227 0.086
response to organic substance GO:0010033 131 0.085
multicellular organismal reproductive process GO:0048609 815 0.083
Worm
nervous system development GO:0007399 253 0.083
cellular biosynthetic process GO:0044249 315 0.082
small gtpase mediated signal transduction GO:0007264 32 0.082
regulation of intracellular signal transduction GO:1902531 77 0.082
regulation of nematode larval development GO:0061062 260 0.082
tissue morphogenesis GO:0048729 65 0.081
single organism behavior GO:0044708 83 0.080
lipid localization GO:0010876 573 0.080
cellular component morphogenesis GO:0032989 318 0.079
system process GO:0003008 136 0.078
regulation of attachment of spindle microtubules to kinetochore GO:0051988 2 0.078
regulation of locomotion GO:0040012 161 0.078
cellular response to chemical stimulus GO:0070887 129 0.077
generation of neurons GO:0048699 235 0.075
anatomical structure formation involved in morphogenesis GO:0048646 250 0.075
regulation of cellular component organization GO:0051128 248 0.074
Worm
cytoskeleton organization GO:0007010 339 0.072
ras protein signal transduction GO:0007265 31 0.071
positive regulation of multicellular organismal process GO:0051240 417 0.071
development of primary sexual characteristics GO:0045137 840 0.071
Worm
maintenance of location GO:0051235 580 0.070
nucleobase containing compound catabolic process GO:0034655 114 0.067
regulation of transport GO:0051049 91 0.066
response to external stimulus GO:0009605 289 0.066
post embryonic organ development GO:0048569 336 0.066
regulation of multicellular organismal process GO:0051239 726 0.066
positive regulation of neurogenesis GO:0050769 4 0.062
positive regulation of neuron differentiation GO:0045666 4 0.061
cell morphogenesis GO:0000902 163 0.060
cellular component biogenesis GO:0044085 297 0.060
cell projection organization GO:0030030 231 0.059
proteolysis GO:0006508 61 0.059
oviposition GO:0018991 364 0.058
Worm
lipid storage GO:0019915 565 0.058
negative regulation of cellular metabolic process GO:0031324 95 0.058
cell division GO:0051301 262 0.058
Worm
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.057
gastrulation GO:0007369 58 0.057
positive regulation of cellular biosynthetic process GO:0031328 109 0.056
regulation of cellular catabolic process GO:0031329 51 0.056
vulval development GO:0040025 333 0.056
intracellular signal transduction GO:0035556 96 0.056
regulation of cellular protein metabolic process GO:0032268 75 0.055
purine containing compound metabolic process GO:0072521 95 0.055
cellular response to inorganic substance GO:0071241 3 0.055
axon guidance GO:0007411 82 0.054
embryonic morphogenesis GO:0048598 152 0.053
sex differentiation GO:0007548 909 0.052
Worm
protein localization GO:0008104 205 0.052
cellular macromolecular complex assembly GO:0034622 184 0.052
protein complex assembly GO:0006461 186 0.051
neuron development GO:0048666 199 0.051
cell surface receptor signaling pathway GO:0007166 149 0.051
positive regulation of growth GO:0045927 369 0.050
single organism transport GO:0044765 447 0.050
regulation of neuron projection development GO:0010975 31 0.050
purine ribonucleotide metabolic process GO:0009150 95 0.049
positive regulation of cell differentiation GO:0045597 8 0.048
cellular component assembly GO:0022607 293 0.048
regulation of axonogenesis GO:0050770 24 0.048
macromolecular complex assembly GO:0065003 193 0.048
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.048
positive regulation of neuron projection development GO:0010976 4 0.047
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.046
multicellular organismal reproductive behavior GO:0033057 384 0.046
Worm
protein complex biogenesis GO:0070271 186 0.046
regulation of meiosis GO:0040020 94 0.045
Worm
regulation of multicellular organismal development GO:2000026 317 0.045
negative regulation of gene expression GO:0010629 217 0.045
organic substance transport GO:0071702 113 0.044
taxis GO:0042330 128 0.043
organonitrogen compound metabolic process GO:1901564 151 0.043
cellular component assembly involved in morphogenesis GO:0010927 183 0.042
mitotic cell cycle process GO:1903047 194 0.042
positive regulation of cell communication GO:0010647 69 0.041
regulation of behavior GO:0050795 97 0.041
mesoderm development GO:0007498 27 0.041
dna metabolic process GO:0006259 74 0.041
female gamete generation GO:0007292 254 0.040
regulation of gene expression GO:0010468 366 0.040
neuron projection extension involved in neuron projection guidance GO:1902284 13 0.040
positive regulation of macromolecule metabolic process GO:0010604 149 0.039
locomotory behavior GO:0007626 40 0.038
multi organism reproductive behavior GO:0044705 387 0.038
Worm
cell cycle GO:0007049 526 0.038
vesicle mediated transport GO:0016192 852 0.038
positive regulation of signaling GO:0023056 66 0.037
neuron projection development GO:0031175 187 0.037
biosynthetic process GO:0009058 323 0.037
carbohydrate derivative metabolic process GO:1901135 141 0.037
cellular localization GO:0051641 360 0.036
aging GO:0007568 812 0.036
rho protein signal transduction GO:0007266 2 0.036
autophagy GO:0006914 29 0.036
protein phosphorylation GO:0006468 85 0.035
cell cell signaling GO:0007267 118 0.035
single organism catabolic process GO:0044712 129 0.034
reproductive system development GO:0061458 850 0.034
Worm
polar body extrusion after meiotic divisions GO:0040038 14 0.034
regulation of growth GO:0040008 409 0.034
positive regulation of developmental growth GO:0048639 354 0.033
endocytosis GO:0006897 819 0.033
regulation of mapk cascade GO:0043408 23 0.033
regulation of anatomical structure size GO:0090066 46 0.033
cellular macromolecule localization GO:0070727 75 0.032
cellular protein localization GO:0034613 75 0.032
mitotic sister chromatid segregation GO:0000070 38 0.032
regulation of jun kinase activity GO:0043506 3 0.032
regulation of ras protein signal transduction GO:0046578 41 0.032
purine ribonucleotide catabolic process GO:0009154 75 0.031
gonad development GO:0008406 840 0.031
Worm
striated muscle cell differentiation GO:0051146 158 0.031
multi organism behavior GO:0051705 389 0.031
Worm
regulation of cytoplasmic transport GO:1903649 3 0.030
regulation of neuron differentiation GO:0045664 40 0.030
nucleoside phosphate metabolic process GO:0006753 108 0.030
posttranscriptional regulation of gene expression GO:0010608 166 0.030
aromatic compound catabolic process GO:0019439 116 0.029
regulation of molecular function GO:0065009 89 0.029
cell part morphogenesis GO:0032990 152 0.029
chemotaxis GO:0006935 120 0.029
negative regulation of signaling GO:0023057 61 0.029
cellular macromolecule catabolic process GO:0044265 73 0.029
carbohydrate derivative catabolic process GO:1901136 82 0.029
positive regulation of phosphate metabolic process GO:0045937 56 0.028
purine nucleotide metabolic process GO:0006163 95 0.028
sexual reproduction GO:0019953 546 0.028
regulation of phosphorus metabolic process GO:0051174 81 0.028
actin cytoskeleton organization GO:0030036 184 0.028
maintenance of location in cell GO:0051651 12 0.028
determination of adult lifespan GO:0008340 812 0.028
regulation of canonical wnt signaling pathway GO:0060828 1 0.027
cellular macromolecule biosynthetic process GO:0034645 247 0.027
regulation of mitotic cell cycle GO:0007346 76 0.027
Worm
protein oligomerization GO:0051259 4 0.027
regulation of protein localization GO:0032880 50 0.027
adult behavior GO:0030534 3 0.026
nucleoside triphosphate catabolic process GO:0009143 72 0.026
regulation of transcription dna templated GO:0006355 164 0.026
reproductive behavior GO:0019098 387 0.026
Worm
muscle structure development GO:0061061 191 0.026
regulation of nucleocytoplasmic transport GO:0046822 3 0.026
positive regulation of cell cycle GO:0045787 55 0.026
Worm
response to biotic stimulus GO:0009607 101 0.025
regulation of mitotic spindle organization GO:0060236 3 0.025
regulation of microtubule based process GO:0032886 21 0.025
heterocycle catabolic process GO:0046700 119 0.025
genitalia development GO:0048806 741 0.025
Worm
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.025
regulation of vulval development GO:0040028 248 0.025
myosin filament organization GO:0031033 138 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 20 0.024
regulation of nitrogen compound metabolic process GO:0051171 222 0.024
secretion GO:0046903 147 0.024
cell proliferation GO:0008283 116 0.024
Worm
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.024
nucleotide catabolic process GO:0009166 77 0.024
ubiquitin dependent protein catabolic process GO:0006511 32 0.024
regulation of developmental growth GO:0048638 389 0.023
negative regulation of response to stimulus GO:0048585 73 0.023
maintenance of protein location GO:0045185 15 0.023
positive regulation of rna metabolic process GO:0051254 103 0.023
cellular protein catabolic process GO:0044257 37 0.023
hermaphrodite genitalia development GO:0040035 734 0.023
Worm
regulation of cell morphogenesis GO:0022604 40 0.023
regulation of catalytic activity GO:0050790 78 0.023
actomyosin structure organization GO:0031032 154 0.023
covalent chromatin modification GO:0016569 30 0.023
small molecule metabolic process GO:0044281 186 0.023
notch signaling pathway GO:0007219 22 0.023
cytoskeleton dependent cytokinesis GO:0061640 35 0.023
regulation of protein catabolic process GO:0042176 13 0.022
cellular protein complex assembly GO:0043623 178 0.022
negative regulation of metabolic process GO:0009892 240 0.022
ovulation GO:0030728 33 0.022
defense response to other organism GO:0098542 100 0.022
ribonucleoside metabolic process GO:0009119 98 0.022
regulation of cell projection organization GO:0031344 38 0.022
response to wounding GO:0009611 4 0.022
cell recognition GO:0008037 85 0.022
regulation of response to stress GO:0080134 28 0.021
negative regulation of cellular process GO:0048523 239 0.021
purine ribonucleoside metabolic process GO:0046128 92 0.021
cellular protein complex localization GO:0034629 3 0.021
multi multicellular organism process GO:0044706 390 0.021
Worm
collagen and cuticulin based cuticle development GO:0040002 99 0.021
regulation of cell cycle GO:0051726 194 0.021
positive regulation of phosphorus metabolic process GO:0010562 56 0.020
lipid biosynthetic process GO:0008610 28 0.020
digestive system development GO:0055123 122 0.020
regulation of anatomical structure morphogenesis GO:0022603 51 0.020
muscle cell differentiation GO:0042692 171 0.020
myofibril assembly GO:0030239 154 0.020
cilium organization GO:0044782 32 0.019
mitotic nuclear division GO:0007067 89 0.019
gene silencing GO:0016458 143 0.019
aromatic compound biosynthetic process GO:0019438 192 0.019
striated muscle cell development GO:0055002 157 0.019
regulation of gene expression epigenetic GO:0040029 163 0.019
positive regulation of rna biosynthetic process GO:1902680 102 0.019
regulation of multicellular organism growth GO:0040014 373 0.019
positive regulation of multicellular organism growth GO:0040018 352 0.019
positive regulation of cell projection organization GO:0031346 4 0.019
positive regulation of protein metabolic process GO:0051247 45 0.019
positive regulation of transcription dna templated GO:0045893 102 0.019
regulation of organelle organization GO:0033043 164 0.019
Worm
purine nucleoside metabolic process GO:0042278 92 0.019
digestive tract morphogenesis GO:0048546 76 0.019
phosphorylation GO:0016310 116 0.019
developmental growth GO:0048589 412 0.019
single organism reproductive process GO:0044702 1196 0.018
Worm
nucleobase containing small molecule metabolic process GO:0055086 115 0.018
multicellular organismal aging GO:0010259 812 0.018
microtubule anchoring GO:0034453 8 0.018
nuclear migration GO:0007097 54 0.018
fertilization GO:0009566 63 0.018
gamete generation GO:0007276 461 0.018
establishment of localization in cell GO:0051649 318 0.018
positive regulation of phosphorylation GO:0042327 27 0.018
regulation of cellular biosynthetic process GO:0031326 189 0.017
macromolecule biosynthetic process GO:0009059 250 0.017
cellular protein complex disassembly GO:0043624 18 0.017
glycosyl compound catabolic process GO:1901658 79 0.017
gene silencing by rna GO:0031047 143 0.016
meiotic cell cycle process GO:1903046 170 0.016
cellular response to organic substance GO:0071310 119 0.016
positive regulation of intracellular transport GO:0032388 2 0.016
actin filament based process GO:0030029 191 0.016
signal transduction by phosphorylation GO:0023014 31 0.016
adult locomotory behavior GO:0008344 1 0.016
regulation of cell death GO:0010941 65 0.016
organic substance biosynthetic process GO:1901576 323 0.016
cuticle development GO:0042335 100 0.016
regulation of apoptotic process GO:0042981 36 0.016
regulation of cell proliferation GO:0042127 105 0.016
Worm
neuron recognition GO:0008038 83 0.016
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.016
regulation of apoptotic signaling pathway GO:2001233 1 0.016
cytokinesis GO:0000910 80 0.016
regulation of phosphorylation GO:0042325 45 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.016
spindle organization GO:0007051 92 0.016
protein localization to organelle GO:0033365 37 0.016
organophosphate metabolic process GO:0019637 125 0.016
mitotic spindle stabilization GO:0043148 2 0.016
positive regulation of intracellular protein transport GO:0090316 2 0.015
single organism cellular localization GO:1902580 72 0.015
developmental growth involved in morphogenesis GO:0060560 37 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.015
ion transport GO:0006811 113 0.015
chromatin modification GO:0016568 32 0.015
posttranscriptional gene silencing by rna GO:0035194 143 0.015
oocyte development GO:0048599 44 0.015
glycosyl compound metabolic process GO:1901657 100 0.015
positive regulation of proteasomal protein catabolic process GO:1901800 1 0.015
negative regulation of vulval development GO:0040027 206 0.015
striated muscle myosin thick filament assembly GO:0071688 138 0.014
maintenance of protein location in cell GO:0032507 12 0.014
positive regulation of protein transport GO:0051222 4 0.014
positive regulation of biosynthetic process GO:0009891 109 0.014
asymmetric protein localization GO:0008105 35 0.014
multicellular organism growth GO:0035264 385 0.014
cell projection morphogenesis GO:0048858 148 0.014
regulation of post embryonic development GO:0048580 260 0.014
modification dependent protein catabolic process GO:0019941 32 0.014
nucleoside phosphate catabolic process GO:1901292 77 0.014
regulation of meiotic cell cycle GO:0051445 136 0.014
Worm
regulation of cell division GO:0051302 142 0.014
Worm
pronuclear migration GO:0035046 51 0.013
myosin filament assembly GO:0031034 138 0.013
mitotic metaphase plate congression GO:0007080 5 0.013
regulation of gtpase activity GO:0043087 30 0.013
spindle checkpoint GO:0031577 4 0.013
secretion by cell GO:0032940 138 0.013
regulation of protein targeting GO:1903533 3 0.013
response to abiotic stimulus GO:0009628 152 0.013
spermatogenesis GO:0007283 41 0.013
ribonucleoprotein complex assembly GO:0022618 4 0.013
oocyte construction GO:0007308 2 0.013
epithelium development GO:0060429 68 0.013
regulation of cellular component size GO:0032535 40 0.013
transcription from rna polymerase ii promoter GO:0006366 149 0.013
chromosome localization GO:0050000 10 0.012
rna interference GO:0016246 137 0.012
protein modification by small protein conjugation or removal GO:0070647 40 0.012
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.012
neuromuscular junction development GO:0007528 2 0.012
guanosine containing compound catabolic process GO:1901069 48 0.012
mesoderm morphogenesis GO:0048332 24 0.012
positive regulation of catabolic process GO:0009896 38 0.012
sphingolipid biosynthetic process GO:0030148 2 0.012
organonitrogen compound catabolic process GO:1901565 90 0.012
proteasomal protein catabolic process GO:0010498 20 0.012
positive regulation of nucleic acid templated transcription GO:1903508 102 0.012
regionalization GO:0003002 31 0.012
regulation of reproductive process GO:2000241 66 0.012
synaptic transmission GO:0007268 106 0.012
tube morphogenesis GO:0035239 79 0.012
positive regulation of cellular catabolic process GO:0031331 35 0.012
defense response to fungus GO:0050832 19 0.012
regulation of macromolecule biosynthetic process GO:0010556 189 0.012
male anatomical structure morphogenesis GO:0090598 78 0.012
anatomical structure homeostasis GO:0060249 11 0.012
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.011
Worm
nucleoside triphosphate metabolic process GO:0009141 87 0.011
establishment of spindle localization GO:0051293 51 0.011
rna metabolic process GO:0016070 228 0.011
ribonucleoside triphosphate metabolic process GO:0009199 87 0.011
single fertilization GO:0007338 61 0.011
negative regulation of signal transduction GO:0009968 60 0.011
neuron apoptotic process GO:0051402 4 0.011
positive regulation of intracellular signal transduction GO:1902533 24 0.011
negative regulation of cell communication GO:0010648 61 0.011
purine nucleotide catabolic process GO:0006195 75 0.011
excretion GO:0007588 49 0.010
sensory organ morphogenesis GO:0090596 2 0.010
ribonucleotide metabolic process GO:0009259 99 0.010
cellular response to endogenous stimulus GO:0071495 32 0.010
regulation of lipid biosynthetic process GO:0046890 1 0.010
cellular response to abiotic stimulus GO:0071214 4 0.010
nucleoside catabolic process GO:0009164 78 0.010
regulation of cell development GO:0060284 49 0.010
spindle localization GO:0051653 51 0.010

cki-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.014
disease of cellular proliferation DOID:14566 0 0.011