Caenorhabditis elegans

64 known processes

lin-23 (CELE_K10B2.1)

Protein LIN-23

lin-23 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organelle organization GO:0006996 783 0.665
Fly
transport GO:0006810 1093 0.524
cell migration GO:0016477 306 0.507
Fly
cell part morphogenesis GO:0032990 152 0.457
cell cycle process GO:0022402 482 0.403
Fly
locomotion GO:0040011 1634 0.392
programmed cell death GO:0012501 500 0.392
Fly
positive regulation of cellular process GO:0048522 332 0.382
Human Mouse Fly
cell morphogenesis GO:0000902 163 0.380
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.351
Mouse
aromatic compound biosynthetic process GO:0019438 192 0.350
Human Mouse
death GO:0016265 547 0.340
Fly
rna metabolic process GO:0016070 228 0.338
Human Mouse
neuron differentiation GO:0030182 217 0.333
regulation of nucleic acid templated transcription GO:1903506 165 0.326
Human Mouse
single organism signaling GO:0044700 401 0.321
Mouse Fly
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.320
Human Mouse Fly
protein metabolic process GO:0019538 422 0.319
Human Mouse Fly
single organism organelle organization GO:1902589 501 0.301
Fly
gene expression GO:0010467 412 0.292
Human Mouse
cellular protein modification process GO:0006464 207 0.287
Human Mouse Fly
regulation of rna metabolic process GO:0051252 173 0.280
Human Mouse
regulation of cellular component organization GO:0051128 248 0.279
Fly
rna biosynthetic process GO:0032774 169 0.278
Human Mouse
regulation of gene expression GO:0010468 366 0.271
Human Mouse
cell cycle GO:0007049 526 0.271
Mouse Fly
cellular component morphogenesis GO:0032989 318 0.268
regulation of cellular biosynthetic process GO:0031326 189 0.262
Human Mouse
receptor mediated endocytosis GO:0006898 715 0.257
cell motility GO:0048870 313 0.256
Fly
cell death GO:0008219 547 0.245
Fly
macromolecule modification GO:0043412 218 0.242
Human Mouse Fly
signaling GO:0023052 401 0.238
Mouse Fly
regulation of macromolecule metabolic process GO:0060255 421 0.234
Human Mouse Fly
cell morphogenesis involved in differentiation GO:0000904 112 0.231
Fly
single organism localization GO:1902578 518 0.231
Mouse Fly
positive regulation of nucleic acid templated transcription GO:1903508 102 0.229
Mouse
body morphogenesis GO:0010171 620 0.227
cell projection morphogenesis GO:0048858 148 0.226
regulation of macromolecule biosynthetic process GO:0010556 189 0.226
Human Mouse
positive regulation of macromolecule metabolic process GO:0010604 149 0.223
Human Mouse
single organism transport GO:0044765 447 0.221
Mouse Fly
nucleic acid templated transcription GO:0097659 169 0.220
Human Mouse
axonogenesis GO:0007409 102 0.219
generation of neurons GO:0048699 235 0.215
regulation of nitrogen compound metabolic process GO:0051171 222 0.215
Human Mouse Fly
post embryonic development GO:0009791 2152 0.214
apoptotic process GO:0006915 478 0.211
Fly
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.210
axon development GO:0061564 163 0.209
regulation of developmental process GO:0050793 684 0.208
Fly
mitotic cell cycle process GO:1903047 194 0.204
Fly
regulation of transcription dna templated GO:0006355 164 0.201
Human Mouse
cellular component assembly GO:0022607 293 0.201
Fly
localization of cell GO:0051674 313 0.196
Fly
regulation of multicellular organismal development GO:2000026 317 0.193
Fly
cellular protein metabolic process GO:0044267 279 0.191
Human Mouse Fly
positive regulation of cellular biosynthetic process GO:0031328 109 0.186
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.180
Mouse
neuron projection development GO:0031175 187 0.177
positive regulation of metabolic process GO:0009893 187 0.176
Human Mouse
protein localization GO:0008104 205 0.175
Mouse Fly
positive regulation of cellular metabolic process GO:0031325 178 0.173
Human Mouse
neuron development GO:0048666 199 0.167
negative regulation of cellular process GO:0048523 239 0.166
establishment of localization GO:0051234 1171 0.164
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.162
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.162
cellular component movement GO:0006928 388 0.160
Fly
protein modification process GO:0036211 207 0.159
Human Mouse Fly
aging GO:0007568 812 0.158
multi multicellular organism process GO:0044706 390 0.157
regulation of vulval development GO:0040028 248 0.155
negative regulation of biological process GO:0048519 567 0.148
regulation of primary metabolic process GO:0080090 292 0.148
Human Mouse Fly
positive regulation of transcription dna templated GO:0045893 102 0.145
Mouse
organic substance catabolic process GO:1901575 294 0.137
Human Mouse
organelle fission GO:0048285 363 0.131
Fly
cellular biosynthetic process GO:0044249 315 0.131
Human Mouse
transcription dna templated GO:0006351 168 0.131
Human Mouse
organ development GO:0048513 1102 0.128
response to external stimulus GO:0009605 289 0.128
embryo development GO:0009790 3052 0.125
heterocycle biosynthetic process GO:0018130 187 0.124
Human Mouse
vesicle mediated transport GO:0016192 852 0.124
meiotic cell cycle process GO:1903046 170 0.120
establishment of localization in cell GO:0051649 318 0.118
Mouse Fly
catabolic process GO:0009056 318 0.118
Human Mouse
neurogenesis GO:0022008 236 0.117
regulation of post embryonic development GO:0048580 260 0.116
nucleobase containing compound metabolic process GO:0006139 406 0.115
Human Mouse Fly
nucleic acid metabolic process GO:0090304 299 0.115
Human Mouse Fly
organic substance biosynthetic process GO:1901576 323 0.115
Human Mouse
cellular response to stress GO:0033554 162 0.112
determination of adult lifespan GO:0008340 812 0.111
regulation of biosynthetic process GO:0009889 189 0.110
Human Mouse
embryo development ending in birth or egg hatching GO:0009792 2992 0.109
multicellular organismal aging GO:0010259 812 0.108
neuron projection morphogenesis GO:0048812 114 0.108
protein catabolic process GO:0030163 162 0.107
Human Mouse
negative regulation of macromolecule metabolic process GO:0010605 229 0.107
Human
post embryonic organ development GO:0048569 336 0.105
macromolecular complex subunit organization GO:0043933 320 0.105
organic cyclic compound biosynthetic process GO:1901362 195 0.104
Human Mouse
chromosome segregation GO:0007059 180 0.103
endocytosis GO:0006897 819 0.101
cellular localization GO:0051641 360 0.100
Mouse Fly
regulation of multicellular organismal process GO:0051239 726 0.099
Fly
regulation of metabolic process GO:0019222 478 0.097
Human Mouse Fly
nucleobase containing compound biosynthetic process GO:0034654 184 0.096
Human Mouse
ribosome biogenesis GO:0042254 4 0.096
multi organism behavior GO:0051705 389 0.096
phosphorus metabolic process GO:0006793 232 0.094
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.092
Human Mouse
organelle assembly GO:0070925 214 0.092
Fly
regulation of transport GO:0051049 91 0.091
Mouse Fly
macromolecule localization GO:0033036 771 0.091
Mouse Fly
negative regulation of multicellular organismal process GO:0051241 236 0.090
Fly
regulation of response to stimulus GO:0048583 243 0.089
Mouse Fly
regulation of mitotic cell cycle GO:0007346 76 0.088
Fly
vulval development GO:0040025 333 0.088
regulation of biological quality GO:0065008 741 0.085
Human Fly
axon guidance GO:0007411 82 0.084
behavior GO:0007610 527 0.083
Fly
negative regulation of cell cycle GO:0045786 53 0.083
regulation of rna biosynthetic process GO:2001141 165 0.082
Human Mouse
negative regulation of nematode larval development GO:0061064 208 0.080
single organism membrane organization GO:0044802 35 0.080
negative regulation of post embryonic development GO:0048581 208 0.080
negative regulation of vulval development GO:0040027 206 0.079
growth GO:0040007 562 0.078
secretion by cell GO:0032940 138 0.078
neuron projection guidance GO:0097485 82 0.077
regulation of organelle organization GO:0033043 164 0.076
Fly
phosphate containing compound metabolic process GO:0006796 232 0.075
Mouse
cellular component biogenesis GO:0044085 297 0.075
Fly
regulation of protein metabolic process GO:0051246 81 0.075
Human Mouse
chromosome organization GO:0051276 104 0.074
Fly
macromolecule catabolic process GO:0009057 202 0.073
Human Mouse
canonical wnt signaling pathway GO:0060070 3 0.071
cellular macromolecule localization GO:0070727 75 0.071
Mouse Fly
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.067
Mouse
gonad development GO:0008406 840 0.067
regulation of molecular function GO:0065009 89 0.067
multicellular organismal reproductive process GO:0048609 815 0.066
Fly
single organism reproductive process GO:0044702 1196 0.065
negative regulation of metabolic process GO:0009892 240 0.065
Human
cell projection organization GO:0030030 231 0.065
multi organism reproductive process GO:0044703 867 0.064
Fly
regulation of cell differentiation GO:0045595 81 0.064
Fly
developmental process involved in reproduction GO:0003006 1165 0.062
nervous system development GO:0007399 253 0.062
biosynthetic process GO:0009058 323 0.061
Human Mouse
anatomical structure formation involved in morphogenesis GO:0048646 250 0.061
Zebrafish Fly
regulation of signaling GO:0023051 172 0.060
Mouse Fly
positive regulation of gene expression GO:0010628 112 0.058
Mouse
regulation of cell migration GO:0030334 55 0.058
oocyte construction GO:0007308 2 0.058
cellular nitrogen compound biosynthetic process GO:0044271 192 0.057
Human Mouse
maintenance of location GO:0051235 580 0.057
Fly
inductive cell migration GO:0040039 145 0.057
regulation of vesicle mediated transport GO:0060627 27 0.056
oviposition GO:0018991 364 0.055
regulation of growth GO:0040008 409 0.054
ubiquitin dependent protein catabolic process GO:0006511 32 0.053
Human Mouse
transcription from rna polymerase ii promoter GO:0006366 149 0.053
regulation of cellular metabolic process GO:0031323 305 0.052
Human Mouse Fly
regulation of nematode larval development GO:0061062 260 0.052
positive regulation of transport GO:0051050 32 0.051
Fly
cell proliferation GO:0008283 116 0.050
multicellular organismal reproductive behavior GO:0033057 384 0.050
positive regulation of rna metabolic process GO:0051254 103 0.050
Mouse
lipid storage GO:0019915 565 0.050
muscle tissue development GO:0060537 1 0.049
macromolecule biosynthetic process GO:0009059 250 0.049
Human Mouse
regulation of cellular protein metabolic process GO:0032268 75 0.049
Human Mouse
secretion GO:0046903 147 0.049
organonitrogen compound metabolic process GO:1901564 151 0.049
small molecule metabolic process GO:0044281 186 0.048
lipid localization GO:0010876 573 0.047
cell development GO:0048468 696 0.047
proteolysis GO:0006508 61 0.047
Human Mouse Fly
cellular component assembly involved in morphogenesis GO:0010927 183 0.046
Fly
regulation of developmental growth GO:0048638 389 0.046
organic substance transport GO:0071702 113 0.045
Mouse Fly
meiotic nuclear division GO:0007126 300 0.044
membrane organization GO:0061024 135 0.044
meiotic cell cycle GO:0051321 335 0.044
regulation of cytoskeleton organization GO:0051493 41 0.044
Fly
tissue development GO:0009888 112 0.044
Mouse Fly
tube morphogenesis GO:0035239 79 0.043
Mouse
positive regulation of biosynthetic process GO:0009891 109 0.043
Mouse
positive regulation of secretion GO:0051047 17 0.043
embryonic body morphogenesis GO:0010172 49 0.043
actin filament based process GO:0030029 191 0.043
response to other organism GO:0051707 101 0.043
head development GO:0060322 1 0.042
regulation of cell cycle process GO:0010564 145 0.042
Fly
regulation of cell communication GO:0010646 176 0.042
Mouse Fly
protein complex subunit organization GO:0071822 280 0.041
cellular macromolecule catabolic process GO:0044265 73 0.040
Human Mouse
multicellular organism reproduction GO:0032504 819 0.040
Fly
regulation of cell cycle GO:0051726 194 0.039
Mouse Fly
oocyte axis specification GO:0007309 2 0.039
protein phosphorylation GO:0006468 85 0.039
cell cell signaling GO:0007267 118 0.039
negative regulation of gene expression GO:0010629 217 0.039
Human
nucleotide metabolic process GO:0009117 108 0.039
reproductive structure development GO:0048608 850 0.039
positive regulation of multicellular organismal process GO:0051240 417 0.038
sex differentiation GO:0007548 909 0.038
gene silencing GO:0016458 143 0.038
female meiotic division GO:0007143 17 0.038
multicellular organism growth GO:0035264 385 0.037
multi organism reproductive behavior GO:0044705 387 0.037
cellular macromolecular complex assembly GO:0034622 184 0.037
small gtpase mediated signal transduction GO:0007264 32 0.037
actomyosin structure organization GO:0031032 154 0.036
macromolecular complex assembly GO:0065003 193 0.035
striated muscle cell development GO:0055002 157 0.035
chemotaxis GO:0006935 120 0.034
muscle cell development GO:0055001 158 0.034
muscle structure development GO:0061061 191 0.034
regulation of anatomical structure size GO:0090066 46 0.034
cellular protein catabolic process GO:0044257 37 0.033
Human Mouse
male anatomical structure morphogenesis GO:0090598 78 0.033
meiotic chromosome segregation GO:0045132 139 0.033
cellular macromolecule biosynthetic process GO:0034645 247 0.033
Human Mouse
negative regulation of cell communication GO:0010648 61 0.032
Mouse Fly
regulation of canonical wnt signaling pathway GO:0060828 1 0.032
wnt signaling pathway GO:0016055 27 0.032
Fly
posttranscriptional gene silencing by rna GO:0035194 143 0.032
cell division GO:0051301 262 0.031
Fly
phagocytosis GO:0006909 115 0.031
regulation of cellular localization GO:0060341 42 0.031
Mouse Fly
regulation of protein localization GO:0032880 50 0.031
Mouse Fly
negative regulation of developmental process GO:0051093 227 0.031
Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.031
Human Mouse
positive regulation of developmental growth GO:0048639 354 0.030
muscle cell differentiation GO:0042692 171 0.030
mitotic nuclear division GO:0007067 89 0.030
Fly
regulation of multicellular organism growth GO:0040014 373 0.030
striated muscle myosin thick filament assembly GO:0071688 138 0.030
positive regulation of cellular component organization GO:0051130 34 0.030
regulation of cell division GO:0051302 142 0.029
Fly
signal transduction GO:0007165 317 0.029
Mouse Fly
positive regulation of developmental process GO:0051094 408 0.029
dendrite development GO:0016358 42 0.029
negative regulation of response to stimulus GO:0048585 73 0.029
Mouse Fly
positive regulation of neurogenesis GO:0050769 4 0.029
regulation of cellular component size GO:0032535 40 0.028
intracellular signal transduction GO:0035556 96 0.028
Mouse Fly
glycosyl compound metabolic process GO:1901657 100 0.028
actin cytoskeleton organization GO:0030036 184 0.028
posttranscriptional regulation of gene expression GO:0010608 166 0.028
Human
reproductive behavior GO:0019098 387 0.028
male sex differentiation GO:0046661 86 0.027
tube development GO:0035295 126 0.027
Mouse
regulation of gene expression epigenetic GO:0040029 163 0.027
gene silencing by rna GO:0031047 143 0.027
regulation of programmed cell death GO:0043067 50 0.027
Fly
regulation of anatomical structure morphogenesis GO:0022603 51 0.027
collagen and cuticulin based cuticle development GO:0040002 99 0.026
posttranscriptional gene silencing GO:0016441 143 0.026
establishment of protein localization to membrane GO:0090150 3 0.026
taxis GO:0042330 128 0.026
organic cyclic compound catabolic process GO:1901361 119 0.026
regulation of localization GO:0032879 194 0.026
Mouse Fly
myofibril assembly GO:0030239 154 0.026
protein modification by small protein conjugation or removal GO:0070647 40 0.026
Human Mouse Fly
reproductive system development GO:0061458 850 0.026
ribonucleoprotein complex assembly GO:0022618 4 0.026
regulation of protein stability GO:0031647 3 0.025
Human
regulation of synapse assembly GO:0051963 2 0.025
defense response GO:0006952 296 0.025
cytoskeleton organization GO:0007010 339 0.024
Fly
defense response to other organism GO:0098542 100 0.024
regulation of nucleocytoplasmic transport GO:0046822 3 0.024
Mouse Fly
asymmetric cell division GO:0008356 36 0.024
regulation of cellular component movement GO:0051270 62 0.023
synaptic vesicle endocytosis GO:0048488 3 0.023
intracellular transport GO:0046907 77 0.023
Mouse Fly
regulation of catabolic process GO:0009894 57 0.023
Mouse
establishment of nucleus localization GO:0040023 55 0.023
single organism intracellular transport GO:1902582 70 0.023
Mouse Fly
development of primary sexual characteristics GO:0045137 840 0.023
synaptic transmission GO:0007268 106 0.022
cell surface receptor signaling pathway GO:0007166 149 0.022
Fly
endomembrane system organization GO:0010256 22 0.022
digestive tract development GO:0048565 122 0.022
striated muscle cell differentiation GO:0051146 158 0.022
carboxylic acid metabolic process GO:0019752 34 0.022
phagocytosis engulfment GO:0006911 98 0.022
response to external biotic stimulus GO:0043207 101 0.021
sensory organ morphogenesis GO:0090596 2 0.021
nucleoside phosphate metabolic process GO:0006753 108 0.021
gastrulation GO:0007369 58 0.021
purine ribonucleotide metabolic process GO:0009150 95 0.021
dna metabolic process GO:0006259 74 0.021
Fly
microtubule based process GO:0007017 182 0.021
Fly
spindle organization GO:0007051 92 0.020
nucleoside metabolic process GO:0009116 99 0.020
skeletal muscle organ development GO:0060538 3 0.020
regulation of cell motility GO:2000145 57 0.020
neuron recognition GO:0008038 83 0.020
covalent chromatin modification GO:0016569 30 0.019
vesicle organization GO:0016050 15 0.019
establishment of vesicle localization GO:0051650 23 0.019
positive regulation of molecular function GO:0044093 61 0.019
single organism catabolic process GO:0044712 129 0.019
cell type specific apoptotic process GO:0097285 4 0.019
Fly
digestive tract morphogenesis GO:0048546 76 0.019
negative regulation of rna metabolic process GO:0051253 53 0.019
Human
organic acid metabolic process GO:0006082 47 0.019
regulation of secretion GO:0051046 29 0.019
cuticle development GO:0042335 100 0.018
modification dependent macromolecule catabolic process GO:0043632 32 0.018
Human Mouse
protein complex biogenesis GO:0070271 186 0.018
cytokinesis GO:0000910 80 0.018
positive regulation of multicellular organism growth GO:0040018 352 0.018
ras protein signal transduction GO:0007265 31 0.018
defense response to bacterium GO:0042742 86 0.018
cellular response to dna damage stimulus GO:0006974 41 0.018
aromatic compound catabolic process GO:0019439 116 0.018
regulation of phosphate metabolic process GO:0019220 81 0.018
regulation of locomotion GO:0040012 161 0.017
molting cycle GO:0042303 281 0.017
positive regulation of growth GO:0045927 369 0.017
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.017
myosin filament organization GO:0031033 138 0.017
regulation of protein ubiquitination GO:0031396 3 0.017
myosin filament assembly GO:0031034 138 0.017
protein localization to plasma membrane GO:0072659 7 0.017
positive regulation of rna biosynthetic process GO:1902680 102 0.016
Mouse
regulation of filopodium assembly GO:0051489 2 0.016
phosphorylation GO:0016310 116 0.016
ribonucleoside triphosphate metabolic process GO:0009199 87 0.016
epithelial tube morphogenesis GO:0060562 1 0.016
Mouse
pattern specification process GO:0007389 59 0.016
rho protein signal transduction GO:0007266 2 0.016
regulation of signal transduction GO:0009966 135 0.016
Mouse Fly
regulation of secretion by cell GO:1903530 21 0.016
positive regulation of intracellular transport GO:0032388 2 0.016
Fly
nucleoside triphosphate metabolic process GO:0009141 87 0.016
nuclear migration GO:0007097 54 0.016
cellular protein complex assembly GO:0043623 178 0.016
nematode male tail tip morphogenesis GO:0045138 77 0.016
actin cytoskeleton reorganization GO:0031532 4 0.016
protein transport GO:0015031 45 0.016
Mouse Fly
protein modification by small protein conjugation GO:0032446 31 0.015
Human Mouse Fly
oxoacid metabolic process GO:0043436 47 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.015
Human
protein complex assembly GO:0006461 186 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 5 0.015
response to topologically incorrect protein GO:0035966 82 0.015
cellular amine metabolic process GO:0044106 15 0.015
mitotic sister chromatid segregation GO:0000070 38 0.015
regulation of cellular component biogenesis GO:0044087 26 0.015
Fly
apoptotic cell clearance GO:0043277 111 0.015
rna localization GO:0006403 3 0.015
cellular catabolic process GO:0044248 199 0.015
Human Mouse
regulation of catalytic activity GO:0050790 78 0.015
regulation of nervous system development GO:0051960 41 0.015
Fly
actin filament organization GO:0007015 21 0.015
regulation of cell proliferation GO:0042127 105 0.015
regeneration GO:0031099 4 0.015
negative regulation of cellular protein catabolic process GO:1903363 4 0.015
proteasomal protein catabolic process GO:0010498 20 0.015
Human Mouse
regulation of apoptotic signaling pathway GO:2001233 1 0.014
negative regulation of mitotic cell cycle GO:0045930 42 0.014
carbohydrate derivative metabolic process GO:1901135 141 0.014
purine ribonucleoside catabolic process GO:0046130 75 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
gamete generation GO:0007276 461 0.014
Fly
glycosyl compound catabolic process GO:1901658 79 0.014
amine metabolic process GO:0009308 15 0.014
cellular ketone metabolic process GO:0042180 14 0.014
muscle organ development GO:0007517 26 0.014
hermaphrodite genitalia development GO:0040035 734 0.014
response to chemical GO:0042221 356 0.014
Mouse Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.014
Fly
purine ribonucleoside metabolic process GO:0046128 92 0.014
cell matrix adhesion GO:0007160 1 0.014
response to abiotic stimulus GO:0009628 152 0.014
muscle fiber development GO:0048747 2 0.014
regulation of ras protein signal transduction GO:0046578 41 0.014
rna interference GO:0016246 137 0.013
regulation of cell projection assembly GO:0060491 3 0.013
spermatogenesis GO:0007283 41 0.013
negative regulation of signal transduction GO:0009968 60 0.013
Mouse Fly
negative regulation of neurogenesis GO:0050768 4 0.013
Fly
positive regulation of hydrolase activity GO:0051345 38 0.013
neuromuscular junction development GO:0007528 2 0.013
heterocycle catabolic process GO:0046700 119 0.013
activation of ras gtpase activity GO:0032856 3 0.013
regulation of hydrolase activity GO:0051336 45 0.013
lipid metabolic process GO:0006629 77 0.013
response to biotic stimulus GO:0009607 101 0.013
regulation of cell morphogenesis GO:0022604 40 0.013
female gamete generation GO:0007292 254 0.013
Fly
regulation of wnt signaling pathway GO:0030111 9 0.013
Fly
sexual reproduction GO:0019953 546 0.013
Fly
cell recognition GO:0008037 85 0.013
ectoderm development GO:0007398 3 0.013
positive regulation of neuron differentiation GO:0045666 4 0.013
embryonic morphogenesis GO:0048598 152 0.013
organophosphate catabolic process GO:0046434 81 0.012
modification dependent protein catabolic process GO:0019941 32 0.012
Human Mouse
negative regulation of cellular metabolic process GO:0031324 95 0.012
Human
positive regulation of apoptotic process GO:0043065 17 0.012
endosomal transport GO:0016197 26 0.012
organophosphate metabolic process GO:0019637 125 0.012
positive regulation of neuron projection development GO:0010976 4 0.012
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 4 0.012
response to wounding GO:0009611 4 0.012
intracellular receptor signaling pathway GO:0030522 2 0.012
positive regulation of protein transport GO:0051222 4 0.012
Fly
positive regulation of catalytic activity GO:0043085 59 0.012
sex determination GO:0007530 60 0.012
purine nucleoside catabolic process GO:0006152 75 0.012
adult behavior GO:0030534 3 0.012
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 4 0.012
neurological system process GO:0050877 53 0.012
Fly
negative regulation of signaling GO:0023057 61 0.012
Mouse Fly
ribonucleotide catabolic process GO:0009261 75 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.011
regulation of cell development GO:0060284 49 0.011
Fly
cytoskeleton dependent cytokinesis GO:0061640 35 0.011
positive regulation of cell cycle GO:0045787 55 0.011
meiotic cytokinesis GO:0033206 15 0.011
g1 s transition of mitotic cell cycle GO:0000082 2 0.011
nucleobase containing small molecule metabolic process GO:0055086 115 0.011
cell substrate adhesion GO:0031589 1 0.011
germ cell development GO:0007281 351 0.011
Fly
positive regulation of vulval development GO:0040026 52 0.011
actomyosin contractile ring organization GO:0044837 1 0.011
nucleoside triphosphate catabolic process GO:0009143 72 0.011
positive regulation of protein metabolic process GO:0051247 45 0.011
Human
neural precursor cell proliferation GO:0061351 9 0.011
negative regulation of proteasomal protein catabolic process GO:1901799 4 0.011
establishment or maintenance of cell polarity GO:0007163 63 0.011
regulation of cell death GO:0010941 65 0.011
Fly
purine nucleoside monophosphate metabolic process GO:0009126 43 0.011
protein localization to membrane GO:0072657 11 0.011
dna templated transcription initiation GO:0006352 3 0.011
positive regulation of secretion by cell GO:1903532 14 0.011
purine ribonucleotide catabolic process GO:0009154 75 0.011
mesodermal cell migration GO:0008078 9 0.011
regulation of endocytosis GO:0030100 25 0.011
divalent inorganic cation transport GO:0072511 17 0.011
regulation of neurogenesis GO:0050767 40 0.010
Fly
regulation of apoptotic process GO:0042981 36 0.010
Fly
cellular response to abiotic stimulus GO:0071214 4 0.010
cell cycle g1 s phase transition GO:0044843 2 0.010
dauer larval development GO:0040024 92 0.010
developmental growth GO:0048589 412 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.010
Human
bmp signaling pathway GO:0030509 3 0.010
organelle localization GO:0051640 127 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.010
homeostatic process GO:0042592 51 0.010
organ morphogenesis GO:0009887 67 0.010
Mouse

lin-23 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.040
disease of anatomical entity DOID:7 0 0.040
cancer DOID:162 0 0.017
nervous system disease DOID:863 0 0.016
organ system cancer DOID:0050686 0 0.016
cardiovascular system disease DOID:1287 0 0.013
musculoskeletal system disease DOID:17 0 0.010