Caenorhabditis elegans

23 known processes

toe-1 (CELE_ZK430.1)

Protein TOE-1

toe-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.859
gonad development GO:0008406 840 0.801
rrna metabolic process GO:0016072 3 0.761
Yeast Zebrafish
sex differentiation GO:0007548 909 0.758
locomotion GO:0040011 1634 0.746
hermaphrodite genitalia development GO:0040035 734 0.744
multicellular organism reproduction GO:0032504 819 0.694
vesicle mediated transport GO:0016192 852 0.690
post embryonic development GO:0009791 2152 0.685
genitalia development GO:0048806 741 0.645
development of primary sexual characteristics GO:0045137 840 0.632
embryo development GO:0009790 3052 0.625
gamete generation GO:0007276 461 0.619
single organism reproductive process GO:0044702 1196 0.602
reproductive structure development GO:0048608 850 0.598
ribosome biogenesis GO:0042254 4 0.574
Yeast Zebrafish
reproductive system development GO:0061458 850 0.556
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.547
developmental process involved in reproduction GO:0003006 1165 0.533
organ development GO:0048513 1102 0.531
rrna processing GO:0006364 3 0.519
Yeast Zebrafish
cell cycle GO:0007049 526 0.442
gene expression GO:0010467 412 0.440
Yeast Zebrafish
receptor mediated endocytosis GO:0006898 715 0.433
germ cell development GO:0007281 351 0.426
endocytosis GO:0006897 819 0.415
negative regulation of vulval development GO:0040027 206 0.383
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 1 0.376
Yeast
meiotic cell cycle GO:0051321 335 0.373
transport GO:0006810 1093 0.338
establishment of localization GO:0051234 1171 0.321
sexual reproduction GO:0019953 546 0.288
multicellular organismal reproductive process GO:0048609 815 0.272
cell cycle process GO:0022402 482 0.246
macromolecular complex subunit organization GO:0043933 320 0.233
cellular component biogenesis GO:0044085 297 0.218
Yeast Zebrafish
meiotic nuclear division GO:0007126 300 0.176
organelle organization GO:0006996 783 0.173
protein complex subunit organization GO:0071822 280 0.168
meiotic cell cycle process GO:1903046 170 0.159
oviposition GO:0018991 364 0.156
chromosome organization involved in meiosis GO:0070192 25 0.150
regulation of nematode larval development GO:0061062 260 0.149
vulval development GO:0040025 333 0.144
aging GO:0007568 812 0.139
ribonucleoprotein complex assembly GO:0022618 4 0.138
cellular macromolecular complex assembly GO:0034622 184 0.136
single organism organelle organization GO:1902589 501 0.135
determination of adult lifespan GO:0008340 812 0.129
macromolecule localization GO:0033036 771 0.125
multi organism reproductive process GO:0044703 867 0.124
regulation of developmental process GO:0050793 684 0.121
cleavage involved in rrna processing GO:0000469 2 0.118
Yeast
maturation of 5 8s rrna GO:0000460 1 0.118
Yeast
multicellular organismal reproductive behavior GO:0033057 384 0.113
regulation of multicellular organismal process GO:0051239 726 0.110
nucleic acid metabolic process GO:0090304 299 0.106
Yeast Zebrafish
ribonucleoprotein complex biogenesis GO:0022613 8 0.103
Yeast Zebrafish
organelle assembly GO:0070925 214 0.100
cell division GO:0051301 262 0.097
embryonic morphogenesis GO:0048598 152 0.095
negative regulation of nematode larval development GO:0061064 208 0.093
body morphogenesis GO:0010171 620 0.091
rna metabolic process GO:0016070 228 0.091
Yeast Zebrafish
establishment of organelle localization GO:0051656 123 0.090
organelle localization GO:0051640 127 0.088
regulation of gene expression GO:0010468 366 0.088
Yeast Zebrafish
regulation of meiotic cell cycle GO:0051445 136 0.085
oogenesis GO:0048477 229 0.082
localization of cell GO:0051674 313 0.081
negative regulation of post embryonic development GO:0048581 208 0.076
regulation of multicellular organismal development GO:2000026 317 0.075
meiotic chromosome segregation GO:0045132 139 0.075
cell development GO:0048468 696 0.074
regulation of post embryonic development GO:0048580 260 0.071
nervous system development GO:0007399 253 0.071
Fly
lipid localization GO:0010876 573 0.069
cellular component assembly GO:0022607 293 0.067
lipid storage GO:0019915 565 0.067
endonucleolytic cleavage involved in rrna processing GO:0000478 1 0.066
Yeast
regulation of metabolic process GO:0019222 478 0.065
Yeast Zebrafish
establishment of localization in cell GO:0051649 318 0.064
organelle fission GO:0048285 363 0.064
molting cycle GO:0042303 281 0.063
multicellular organismal aging GO:0010259 812 0.062
protein complex assembly GO:0006461 186 0.061
nucleobase containing compound metabolic process GO:0006139 406 0.060
Yeast Zebrafish
negative regulation of multicellular organismal process GO:0051241 236 0.060
digestive system development GO:0055123 122 0.059
regulation of nuclear division GO:0051783 115 0.058
protein complex biogenesis GO:0070271 186 0.057
signaling GO:0023052 401 0.057
microtubule based process GO:0007017 182 0.056
actin cytoskeleton organization GO:0030036 184 0.056
single organism transport GO:0044765 447 0.055
maintenance of location GO:0051235 580 0.053
pronuclear migration GO:0035046 51 0.053
regulation of biological quality GO:0065008 741 0.053
Zebrafish
inductive cell migration GO:0040039 145 0.052
negative regulation of macromolecule metabolic process GO:0010605 229 0.052
cell death GO:0008219 547 0.052
Zebrafish
female gamete generation GO:0007292 254 0.052
multi organism reproductive behavior GO:0044705 387 0.050
macromolecule biosynthetic process GO:0009059 250 0.049
Yeast
signal transduction GO:0007165 317 0.049
post embryonic organ development GO:0048569 336 0.049
positive regulation of cellular process GO:0048522 332 0.048
Yeast
rna processing GO:0006396 34 0.047
Yeast Zebrafish
apoptotic process GO:0006915 478 0.046
Zebrafish
muscle structure development GO:0061061 191 0.046
chromosome segregation GO:0007059 180 0.046
cellular protein complex assembly GO:0043623 178 0.046
fertilization GO:0009566 63 0.046
negative regulation of biological process GO:0048519 567 0.044
Zebrafish
cellular component movement GO:0006928 388 0.044
spindle organization GO:0007051 92 0.043
single fertilization GO:0007338 61 0.043
negative regulation of metabolic process GO:0009892 240 0.042
macromolecular complex assembly GO:0065003 193 0.042
dna templated transcription elongation GO:0006354 1 0.042
anatomical structure formation involved in morphogenesis GO:0048646 250 0.042
cytoskeleton organization GO:0007010 339 0.041
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.041
negative regulation of developmental process GO:0051093 227 0.040
single organism localization GO:1902578 518 0.040
myosin filament assembly GO:0031034 138 0.038
actin filament based process GO:0030029 191 0.038
regulation of meiosis GO:0040020 94 0.038
single organism signaling GO:0044700 401 0.035
regulation of developmental growth GO:0048638 389 0.035
reproductive behavior GO:0019098 387 0.035
programmed cell death GO:0012501 500 0.035
Zebrafish
multi multicellular organism process GO:0044706 390 0.035
regulation of cellular metabolic process GO:0031323 305 0.034
Yeast
gastrulation GO:0007369 58 0.034
organic substance biosynthetic process GO:1901576 323 0.034
Yeast
cell surface receptor signaling pathway GO:0007166 149 0.034
regulation of cell division GO:0051302 142 0.033
biosynthetic process GO:0009058 323 0.033
Yeast
multi organism behavior GO:0051705 389 0.032
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.031
death GO:0016265 547 0.031
Zebrafish
posttranscriptional gene silencing by rna GO:0035194 143 0.031
purine nucleoside triphosphate metabolic process GO:0009144 87 0.030
cellular localization GO:0051641 360 0.030
positive regulation of multicellular organismal process GO:0051240 417 0.030
protein metabolic process GO:0019538 422 0.029
cellular macromolecule biosynthetic process GO:0034645 247 0.029
Yeast
digestive tract development GO:0048565 122 0.029
regulation of gene expression epigenetic GO:0040029 163 0.029
myofibril assembly GO:0030239 154 0.029
cellular component morphogenesis GO:0032989 318 0.028
regulation of multicellular organism growth GO:0040014 373 0.028
developmental growth GO:0048589 412 0.028
regulation of vulval development GO:0040028 248 0.028
positive regulation of multicellular organism growth GO:0040018 352 0.027
rna interference GO:0016246 137 0.027
positive regulation of developmental process GO:0051094 408 0.027
striated muscle myosin thick filament assembly GO:0071688 138 0.026
cytokinesis GO:0000910 80 0.026
muscle cell differentiation GO:0042692 171 0.026
regulation of primary metabolic process GO:0080090 292 0.025
Yeast
gene silencing GO:0016458 143 0.025
oocyte development GO:0048599 44 0.025
establishment of chromosome localization GO:0051303 10 0.025
myosin filament organization GO:0031033 138 0.024
behavior GO:0007610 527 0.024
positive regulation of developmental growth GO:0048639 354 0.024
cell migration GO:0016477 306 0.023
regulation of nitrogen compound metabolic process GO:0051171 222 0.022
Yeast
regulation of cell cycle GO:0051726 194 0.022
negative regulation of gene expression GO:0010629 217 0.022
mitotic spindle organization GO:0007052 81 0.022
macromolecule modification GO:0043412 218 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.022
tube morphogenesis GO:0035239 79 0.022
gene silencing by rna GO:0031047 143 0.021
posttranscriptional regulation of gene expression GO:0010608 166 0.021
Zebrafish
positive regulation of rna metabolic process GO:0051254 103 0.021
Yeast
regulation of cellular component organization GO:0051128 248 0.021
ncrna metabolic process GO:0034660 14 0.020
Yeast Zebrafish
regulation of cell communication GO:0010646 176 0.020
synaptonemal complex assembly GO:0007130 6 0.020
cell motility GO:0048870 313 0.020
positive regulation of cellular metabolic process GO:0031325 178 0.020
Yeast
regulation of growth GO:0040008 409 0.020
regulation of response to stimulus GO:0048583 243 0.020
striated muscle cell differentiation GO:0051146 158 0.020
phosphorylation GO:0016310 116 0.020
negative regulation of cellular process GO:0048523 239 0.019
Zebrafish
actomyosin structure organization GO:0031032 154 0.019
nucleobase containing compound catabolic process GO:0034655 114 0.018
synaptonemal complex organization GO:0070193 8 0.018
posttranscriptional gene silencing GO:0016441 143 0.018
regulation of cell proliferation GO:0042127 105 0.018
multicellular organism growth GO:0035264 385 0.018
microtubule polymerization or depolymerization GO:0031109 22 0.017
chromosome organization GO:0051276 104 0.017
growth GO:0040007 562 0.017
water homeostasis GO:0030104 5 0.017
regulation of organelle organization GO:0033043 164 0.017
glycosyl compound metabolic process GO:1901657 100 0.017
defense response to gram negative bacterium GO:0050829 64 0.017
cellular nitrogen compound biosynthetic process GO:0044271 192 0.016
Yeast
regulation of rna metabolic process GO:0051252 173 0.016
Yeast
cell proliferation GO:0008283 116 0.016
oocyte differentiation GO:0009994 45 0.016
nucleic acid phosphodiester bond hydrolysis GO:0090305 28 0.016
Yeast
cellular component assembly involved in morphogenesis GO:0010927 183 0.016
phosphate containing compound metabolic process GO:0006796 232 0.015
cell projection morphogenesis GO:0048858 148 0.015
organic cyclic compound catabolic process GO:1901361 119 0.015
small molecule metabolic process GO:0044281 186 0.015
negative regulation of protein metabolic process GO:0051248 27 0.015
regulation of cell cycle process GO:0010564 145 0.015
striated muscle cell development GO:0055002 157 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.014
Yeast
canonical wnt signaling pathway GO:0060070 3 0.014
mitotic nuclear division GO:0007067 89 0.014
regulation of canonical wnt signaling pathway GO:0060828 1 0.014
cell morphogenesis GO:0000902 163 0.013
purine ribonucleoside metabolic process GO:0046128 92 0.013
purine nucleoside metabolic process GO:0042278 92 0.013
mitotic cell cycle process GO:1903047 194 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.013
Yeast
synapsis GO:0007129 10 0.013
male gamete generation GO:0048232 41 0.013
nucleobase containing compound biosynthetic process GO:0034654 184 0.013
Yeast
oocyte axis specification GO:0007309 2 0.013
regulation of anatomical structure morphogenesis GO:0022603 51 0.013
organic cyclic compound biosynthetic process GO:1901362 195 0.013
Yeast
phagocytosis GO:0006909 115 0.012
single organism catabolic process GO:0044712 129 0.012
regulation of macromolecule metabolic process GO:0060255 421 0.012
Yeast Zebrafish
regulation of microtubule cytoskeleton organization GO:0070507 21 0.012
nucleoside phosphate metabolic process GO:0006753 108 0.012
purine containing compound metabolic process GO:0072521 95 0.012
purine nucleotide metabolic process GO:0006163 95 0.012
neuron development GO:0048666 199 0.012
digestive tract morphogenesis GO:0048546 76 0.011
feminization of hermaphroditic germ line GO:0040022 34 0.011
trna processing GO:0008033 3 0.011
phosphorus metabolic process GO:0006793 232 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.011
Yeast
establishment or maintenance of cell polarity GO:0007163 63 0.010
ribonucleoside metabolic process GO:0009119 98 0.010
ncrna processing GO:0034470 11 0.010
Yeast Zebrafish
aromatic compound biosynthetic process GO:0019438 192 0.010
Yeast
chromosome localization GO:0050000 10 0.010
spermatogenesis GO:0007283 41 0.010
regulation of molecular function GO:0065009 89 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.010
sex determination GO:0007530 60 0.010

toe-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.010
nervous system disease DOID:863 0 0.010