Caenorhabditis elegans

82 known processes

lex-1 (CELE_F11A10.1)

Protein LEX-1

lex-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2152 0.830
organ development GO:0048513 1102 0.799
developmental process involved in reproduction GO:0003006 1165 0.794
embryo development ending in birth or egg hatching GO:0009792 2992 0.722
embryo development GO:0009790 3052 0.657
regulation of vulval development GO:0040028 248 0.655
receptor mediated endocytosis GO:0006898 715 0.584
positive regulation of vulval development GO:0040026 52 0.583
meiotic cell cycle GO:0051321 335 0.539
chromosome organization GO:0051276 104 0.500
endocytosis GO:0006897 819 0.497
nucleobase containing compound metabolic process GO:0006139 406 0.447
sex differentiation GO:0007548 909 0.402
multicellular organism reproduction GO:0032504 819 0.395
cell fate commitment GO:0045165 139 0.358
negative regulation of vulval development GO:0040027 206 0.354
locomotion GO:0040011 1634 0.349
reproductive structure development GO:0048608 850 0.349
organelle organization GO:0006996 783 0.340
development of primary sexual characteristics GO:0045137 840 0.318
meiotic cell cycle process GO:1903046 170 0.316
body morphogenesis GO:0010171 620 0.309
transport GO:0006810 1093 0.301
multicellular organismal reproductive process GO:0048609 815 0.292
regulation of metabolic process GO:0019222 478 0.287
negative regulation of biological process GO:0048519 567 0.280
Yeast
cell cycle GO:0007049 526 0.268
regulation of nematode larval development GO:0061062 260 0.266
gonad development GO:0008406 840 0.251
macromolecule biosynthetic process GO:0009059 250 0.250
Human Yeast
nucleobase containing compound biosynthetic process GO:0034654 184 0.234
Human Yeast
organelle fission GO:0048285 363 0.229
single organism reproductive process GO:0044702 1196 0.228
regulation of rna metabolic process GO:0051252 173 0.220
Human Yeast
regulation of post embryonic development GO:0048580 260 0.219
establishment of localization GO:0051234 1171 0.214
sexual reproduction GO:0019953 546 0.213
regulation of meiotic cell cycle GO:0051445 136 0.201
genitalia development GO:0048806 741 0.197
nucleic acid metabolic process GO:0090304 299 0.195
regulation of biological quality GO:0065008 741 0.191
hermaphrodite genitalia development GO:0040035 734 0.186
negative regulation of nematode larval development GO:0061064 208 0.181
positive regulation of rna metabolic process GO:0051254 103 0.181
Human Yeast
signaling GO:0023052 401 0.180
regulation of developmental process GO:0050793 684 0.174
rna metabolic process GO:0016070 228 0.169
Human Yeast
gene expression GO:0010467 412 0.168
Human Yeast
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.168
germ cell development GO:0007281 351 0.166
cell development GO:0048468 696 0.159
post embryonic organ development GO:0048569 336 0.156
vulval development GO:0040025 333 0.151
cell motility GO:0048870 313 0.149
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.146
Human Yeast
negative regulation of developmental process GO:0051093 227 0.145
dna metabolic process GO:0006259 74 0.144
organic substance biosynthetic process GO:1901576 323 0.139
Human Yeast
regulation of multicellular organismal development GO:2000026 317 0.133
gamete generation GO:0007276 461 0.132
biosynthetic process GO:0009058 323 0.132
Human Yeast
multicellular organismal reproductive behavior GO:0033057 384 0.131
meiotic nuclear division GO:0007126 300 0.126
signal transduction GO:0007165 317 0.124
regulation of gene expression GO:0010468 366 0.124
Human Yeast
cellular macromolecule biosynthetic process GO:0034645 247 0.122
Human Yeast
positive regulation of transcription dna templated GO:0045893 102 0.120
Human Yeast
meiotic chromosome segregation GO:0045132 139 0.114
negative regulation of post embryonic development GO:0048581 208 0.113
cellular protein modification process GO:0006464 207 0.111
vesicle mediated transport GO:0016192 852 0.107
regulation of transcription dna templated GO:0006355 164 0.107
Human Yeast
multi organism reproductive process GO:0044703 867 0.107
macromolecule localization GO:0033036 771 0.105
regulation of nuclear division GO:0051783 115 0.103
chromosome organization involved in meiosis GO:0070192 25 0.096
positive regulation of gene expression GO:0010628 112 0.094
Human Yeast
nucleic acid templated transcription GO:0097659 169 0.094
Human Yeast
regulation of cell cycle process GO:0010564 145 0.093
negative regulation of metabolic process GO:0009892 240 0.092
Yeast
growth GO:0040007 562 0.089
Yeast
aging GO:0007568 812 0.088
macromolecule catabolic process GO:0009057 202 0.088
organic cyclic compound biosynthetic process GO:1901362 195 0.087
Human Yeast
regulation of gene expression epigenetic GO:0040029 163 0.087
Yeast
single organism signaling GO:0044700 401 0.087
aromatic compound biosynthetic process GO:0019438 192 0.085
Human Yeast
protein metabolic process GO:0019538 422 0.084
reproductive system development GO:0061458 850 0.082
positive regulation of multicellular organismal process GO:0051240 417 0.082
cellular biosynthetic process GO:0044249 315 0.081
Human Yeast
organic substance catabolic process GO:1901575 294 0.081
Human
nuclear migration GO:0007097 54 0.079
regulation of meiosis GO:0040020 94 0.078
maintenance of location GO:0051235 580 0.077
cell cycle process GO:0022402 482 0.077
positive regulation of biosynthetic process GO:0009891 109 0.075
Human Yeast
regulation of macromolecule metabolic process GO:0060255 421 0.075
cellular nitrogen compound biosynthetic process GO:0044271 192 0.074
Human Yeast
programmed cell death GO:0012501 500 0.072
cuticle development GO:0042335 100 0.072
oogenesis GO:0048477 229 0.072
regulation of cellular metabolic process GO:0031323 305 0.071
dna templated transcription elongation GO:0006354 1 0.071
localization of cell GO:0051674 313 0.068
multi multicellular organism process GO:0044706 390 0.068
reproductive behavior GO:0019098 387 0.067
chromosome segregation GO:0007059 180 0.067
head development GO:0060322 1 0.066
lipid storage GO:0019915 565 0.064
response to external stimulus GO:0009605 289 0.064
oviposition GO:0018991 364 0.064
cell division GO:0051301 262 0.063
chromatin organization GO:0006325 32 0.063
lipid localization GO:0010876 573 0.063
multi organism reproductive behavior GO:0044705 387 0.063
cell death GO:0008219 547 0.063
neuron projection development GO:0031175 187 0.063
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.062
Yeast
single organism transport GO:0044765 447 0.061
transcription from rna polymerase ii promoter GO:0006366 149 0.059
Yeast
protein modification process GO:0036211 207 0.058
determination of adult lifespan GO:0008340 812 0.057
ras protein signal transduction GO:0007265 31 0.057
transcription dna templated GO:0006351 168 0.057
Human Yeast
cytoskeleton organization GO:0007010 339 0.057
macromolecule modification GO:0043412 218 0.055
gene silencing by rna GO:0031047 143 0.055
negative regulation of macromolecule metabolic process GO:0010605 229 0.054
Yeast
posttranscriptional gene silencing by rna GO:0035194 143 0.053
regulation of cell fate commitment GO:0010453 22 0.053
posttranscriptional regulation of gene expression GO:0010608 166 0.053
heterocycle biosynthetic process GO:0018130 187 0.052
Human Yeast
posttranscriptional gene silencing GO:0016441 143 0.052
single organism organelle organization GO:1902589 501 0.052
nervous system development GO:0007399 253 0.051
negative regulation of cellular process GO:0048523 239 0.051
Yeast
purine ribonucleoside catabolic process GO:0046130 75 0.050
Human
catabolic process GO:0009056 318 0.049
Human
protein modification by small protein conjugation or removal GO:0070647 40 0.049
rna biosynthetic process GO:0032774 169 0.049
Human Yeast
rna interference GO:0016246 137 0.048
regulation of cellular component organization GO:0051128 248 0.048
protein complex biogenesis GO:0070271 186 0.048
regulation of nitrogen compound metabolic process GO:0051171 222 0.048
neuron differentiation GO:0030182 217 0.047
cellular nitrogen compound catabolic process GO:0044270 119 0.047
Human
regulation of multicellular organismal process GO:0051239 726 0.047
negative regulation of gene expression epigenetic GO:0045814 2 0.046
Yeast
cellular response to stress GO:0033554 162 0.046
developmental growth GO:0048589 412 0.045
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.045
Yeast
macromolecular complex subunit organization GO:0043933 320 0.045
response to chemical GO:0042221 356 0.044
covalent chromatin modification GO:0016569 30 0.044
phosphate containing compound metabolic process GO:0006796 232 0.043
Human
cellular component biogenesis GO:0044085 297 0.043
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.042
female gamete generation GO:0007292 254 0.042
chromatin modification GO:0016568 32 0.041
regulation of cell differentiation GO:0045595 81 0.041
cellular component assembly GO:0022607 293 0.041
negative regulation of rna biosynthetic process GO:1902679 53 0.040
Yeast
positive regulation of growth GO:0045927 369 0.040
Yeast
cellular catabolic process GO:0044248 199 0.040
Human
cell projection morphogenesis GO:0048858 148 0.040
negative regulation of gene expression GO:0010629 217 0.038
Yeast
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.038
Human
regulation of cell cycle GO:0051726 194 0.037
regulation of organelle organization GO:0033043 164 0.037
positive regulation of macromolecule metabolic process GO:0010604 149 0.036
Human Yeast
dna conformation change GO:0071103 11 0.036
regulation of mitotic cell cycle GO:0007346 76 0.036
macromolecular complex assembly GO:0065003 193 0.036
single organism biosynthetic process GO:0044711 91 0.035
small molecule metabolic process GO:0044281 186 0.034
Human
negative regulation of nucleic acid templated transcription GO:1903507 53 0.034
Yeast
regulation of cellular biosynthetic process GO:0031326 189 0.034
Human Yeast
positive regulation of nucleic acid templated transcription GO:1903508 102 0.033
Human Yeast
regulation of macromolecule biosynthetic process GO:0010556 189 0.033
Human Yeast
carbohydrate derivative catabolic process GO:1901136 82 0.033
Human
positive regulation of multicellular organism growth GO:0040018 352 0.033
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.033
Yeast
positive regulation of developmental process GO:0051094 408 0.033
regulation of growth GO:0040008 409 0.033
Yeast
intracellular signal transduction GO:0035556 96 0.032
mitotic cell cycle checkpoint GO:0007093 5 0.032
multi organism behavior GO:0051705 389 0.032
inductive cell migration GO:0040039 145 0.032
taxis GO:0042330 128 0.032
mitotic cell cycle process GO:1903047 194 0.032
cellular component movement GO:0006928 388 0.031
striated muscle myosin thick filament assembly GO:0071688 138 0.031
multicellular organismal aging GO:0010259 812 0.031
multicellular organism growth GO:0035264 385 0.030
cellular protein complex assembly GO:0043623 178 0.030
cellular component morphogenesis GO:0032989 318 0.030
apoptotic process GO:0006915 478 0.030
regulation of cell proliferation GO:0042127 105 0.030
anatomical structure formation involved in morphogenesis GO:0048646 250 0.029
cell projection organization GO:0030030 231 0.029
cellular response to dna damage stimulus GO:0006974 41 0.028
oxoacid metabolic process GO:0043436 47 0.028
positive regulation of post embryonic development GO:0048582 54 0.028
digestive system development GO:0055123 122 0.028
organonitrogen compound metabolic process GO:1901564 151 0.028
Human
death GO:0016265 547 0.028
cell proliferation GO:0008283 116 0.027
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.027
Yeast
small gtpase mediated signal transduction GO:0007264 32 0.027
digestive tract development GO:0048565 122 0.027
cellular component maintenance GO:0043954 1 0.027
regulation of rna biosynthetic process GO:2001141 165 0.026
Human Yeast
behavior GO:0007610 527 0.026
negative regulation of rna metabolic process GO:0051253 53 0.026
Yeast
protein catabolic process GO:0030163 162 0.025
positive regulation of developmental growth GO:0048639 354 0.025
purine ribonucleoside metabolic process GO:0046128 92 0.025
Human
phagocytosis engulfment GO:0006911 98 0.025
histone modification GO:0016570 30 0.025
regulation of multicellular organism growth GO:0040014 373 0.025
negative regulation of transcription dna templated GO:0045892 53 0.025
Yeast
dna packaging GO:0006323 7 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.024
Yeast
cellular protein metabolic process GO:0044267 279 0.024
cellular localization GO:0051641 360 0.024
cellular response to organic substance GO:0071310 119 0.024
gene silencing GO:0016458 143 0.023
Yeast
cell migration GO:0016477 306 0.023
regulation of cell communication GO:0010646 176 0.023
regulation of ras protein signal transduction GO:0046578 41 0.023
negative regulation of cell cycle GO:0045786 53 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.022
Human Yeast
negative regulation of multicellular organismal process GO:0051241 236 0.022
regulation of developmental growth GO:0048638 389 0.022
nucleobase containing compound catabolic process GO:0034655 114 0.022
Human
muscle cell differentiation GO:0042692 171 0.022
protein localization GO:0008104 205 0.022
axon development GO:0061564 163 0.022
chromatin remodeling GO:0006338 2 0.022
regulation of nucleic acid templated transcription GO:1903506 165 0.022
Human Yeast
negative regulation of biosynthetic process GO:0009890 65 0.021
Yeast
single organism localization GO:1902578 518 0.020
positive regulation of cellular biosynthetic process GO:0031328 109 0.020
Human Yeast
protein complex subunit organization GO:0071822 280 0.020
generation of neurons GO:0048699 235 0.020
positive regulation of cellular metabolic process GO:0031325 178 0.020
Human Yeast
positive regulation of cellular process GO:0048522 332 0.020
Human Yeast
response to wounding GO:0009611 4 0.019
striated muscle cell development GO:0055002 157 0.019
collagen and cuticulin based cuticle development GO:0040002 99 0.019
establishment of localization in cell GO:0051649 318 0.019
nucleobase containing small molecule metabolic process GO:0055086 115 0.019
Human
microtubule based process GO:0007017 182 0.019
negative regulation of mitotic cell cycle GO:0045930 42 0.019
ubiquitin dependent protein catabolic process GO:0006511 32 0.018
regulation of cell division GO:0051302 142 0.018
organelle assembly GO:0070925 214 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.018
Yeast
glycosyl compound metabolic process GO:1901657 100 0.018
Human
regulation of small gtpase mediated signal transduction GO:0051056 41 0.018
system process GO:0003008 136 0.018
neuron development GO:0048666 199 0.018
dna geometric change GO:0032392 3 0.018
cellular macromolecular complex assembly GO:0034622 184 0.018
negative regulation of cellular biosynthetic process GO:0031327 65 0.018
Yeast
regulation of signaling GO:0023051 172 0.017
establishment of cell polarity GO:0030010 46 0.017
response to oxygen containing compound GO:1901700 44 0.017
cellular amino acid metabolic process GO:0006520 15 0.017
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.017
Human Yeast
oocyte differentiation GO:0009994 45 0.017
aromatic compound catabolic process GO:0019439 116 0.017
Human
mitotic g2 m transition checkpoint GO:0044818 1 0.017
positive regulation of rna biosynthetic process GO:1902680 102 0.016
Human Yeast
organonitrogen compound catabolic process GO:1901565 90 0.016
Human
organophosphate metabolic process GO:0019637 125 0.016
Human
myosin filament organization GO:0031033 138 0.016
response to endoplasmic reticulum stress GO:0034976 71 0.016
regulation of primary metabolic process GO:0080090 292 0.015
myosin filament assembly GO:0031034 138 0.015
embryonic morphogenesis GO:0048598 152 0.015
muscle structure development GO:0061061 191 0.015
single organism catabolic process GO:0044712 129 0.015
Human
sister chromatid segregation GO:0000819 46 0.015
nucleoside metabolic process GO:0009116 99 0.015
Human
regulation of biosynthetic process GO:0009889 189 0.015
Human Yeast
regulation of cellular ketone metabolic process GO:0010565 3 0.015
phosphorylation GO:0016310 116 0.015
protein oligomerization GO:0051259 4 0.014
tube development GO:0035295 126 0.014
cellular macromolecule catabolic process GO:0044265 73 0.014
membrane invagination GO:0010324 98 0.014
nucleotide metabolic process GO:0009117 108 0.014
Human
actin cytoskeleton organization GO:0030036 184 0.014
mitotic spindle organization GO:0007052 81 0.014
cell cycle phase transition GO:0044770 19 0.014
regulation of response to stimulus GO:0048583 243 0.014
response to organic substance GO:0010033 131 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
mrna catabolic process GO:0006402 16 0.014
protein complex assembly GO:0006461 186 0.013
phagocytosis GO:0006909 115 0.013
sensory organ morphogenesis GO:0090596 2 0.013
dendrite development GO:0016358 42 0.013
carbohydrate derivative metabolic process GO:1901135 141 0.013
Human
nucleus localization GO:0051647 55 0.013
muscle cell development GO:0055001 158 0.013
nucleoside phosphate metabolic process GO:0006753 108 0.013
Human
negative regulation of cellular metabolic process GO:0031324 95 0.013
Yeast
molting cycle GO:0042303 281 0.013
membrane organization GO:0061024 135 0.013
organic substance transport GO:0071702 113 0.013
cellular component assembly involved in morphogenesis GO:0010927 183 0.013
positive regulation of catabolic process GO:0009896 38 0.013
mitotic sister chromatid segregation GO:0000070 38 0.013
enzyme linked receptor protein signaling pathway GO:0007167 50 0.012
ribonucleotide catabolic process GO:0009261 75 0.012
Human
regulation of localization GO:0032879 194 0.012
regulation of signal transduction GO:0009966 135 0.012
secretion by cell GO:0032940 138 0.012
organic acid metabolic process GO:0006082 47 0.012
neuron recognition GO:0008038 83 0.012
tissue development GO:0009888 112 0.012
oocyte construction GO:0007308 2 0.012
regulation of intracellular signal transduction GO:1902531 77 0.012
digestive tract morphogenesis GO:0048546 76 0.012
internal peptidyl lysine acetylation GO:0018393 3 0.012
response to oxidative stress GO:0006979 42 0.012
organic cyclic compound catabolic process GO:1901361 119 0.012
Human
response to external biotic stimulus GO:0043207 101 0.012
cellular ketone metabolic process GO:0042180 14 0.012
amine metabolic process GO:0009308 15 0.011
cell cell signaling GO:0007267 118 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.011
Human Yeast
dna duplex unwinding GO:0032508 3 0.011
proteolysis GO:0006508 61 0.011
negative regulation of neurogenesis GO:0050768 4 0.011
nucleic acid transport GO:0050657 3 0.011
mrna metabolic process GO:0016071 31 0.011
striated muscle cell differentiation GO:0051146 158 0.011
neuron projection guidance GO:0097485 82 0.011
cell morphogenesis involved in differentiation GO:0000904 112 0.011
rna catabolic process GO:0006401 21 0.011
peptidyl amino acid modification GO:0018193 58 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
cell surface receptor signaling pathway GO:0007166 149 0.011
myofibril assembly GO:0030239 154 0.011
pronuclear migration GO:0035046 51 0.010
phosphorus metabolic process GO:0006793 232 0.010
Human
negative regulation of cell cycle process GO:0010948 12 0.010
internal protein amino acid acetylation GO:0006475 3 0.010
regulation of chromatin modification GO:1903308 2 0.010
purine nucleotide catabolic process GO:0006195 75 0.010
Human
intracellular transport GO:0046907 77 0.010
purine nucleoside monophosphate metabolic process GO:0009126 43 0.010
Human

lex-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013