Caenorhabditis elegans

54 known processes

ntl-2 (CELE_B0286.4)

Protein NTL-2

ntl-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2152 0.484
organ development GO:0048513 1102 0.473
establishment of localization GO:0051234 1171 0.379
embryo development ending in birth or egg hatching GO:0009792 2992 0.353
regulation of primary metabolic process GO:0080090 292 0.317
Human Fly
hermaphrodite genitalia development GO:0040035 734 0.315
developmental process involved in reproduction GO:0003006 1165 0.308
gene expression GO:0010467 412 0.306
Human Fly
sex differentiation GO:0007548 909 0.296
single organism reproductive process GO:0044702 1196 0.294
embryo development GO:0009790 3052 0.263
regulation of macromolecule metabolic process GO:0060255 421 0.261
Human Fly
negative regulation of biological process GO:0048519 567 0.260
Human Fly
regulation of metabolic process GO:0019222 478 0.248
Human Fly
sexual reproduction GO:0019953 546 0.234
genitalia development GO:0048806 741 0.217
multicellular organismal reproductive process GO:0048609 815 0.211
organic cyclic compound catabolic process GO:1901361 119 0.210
Fly
negative regulation of translation GO:0017148 10 0.208
Fly
negative regulation of cellular process GO:0048523 239 0.203
Human Fly
nucleobase containing compound metabolic process GO:0006139 406 0.201
Human Fly
negative regulation of metabolic process GO:0009892 240 0.196
Human Fly
negative regulation of macromolecule metabolic process GO:0010605 229 0.195
Human Fly
vulval development GO:0040025 333 0.192
protein metabolic process GO:0019538 422 0.191
Fly
gamete generation GO:0007276 461 0.190
regulation of gene expression GO:0010468 366 0.183
Human Fly
reproductive structure development GO:0048608 850 0.176
regulation of translation GO:0006417 19 0.164
Fly
nucleobase containing compound catabolic process GO:0034655 114 0.158
Fly
macromolecule catabolic process GO:0009057 202 0.156
Fly
locomotion GO:0040011 1634 0.151
vesicle mediated transport GO:0016192 852 0.143
regulation of biosynthetic process GO:0009889 189 0.143
Human Fly
catabolic process GO:0009056 318 0.143
Fly
receptor mediated endocytosis GO:0006898 715 0.142
aging GO:0007568 812 0.137
regulation of macromolecule biosynthetic process GO:0010556 189 0.137
Human Fly
mitotic cell cycle process GO:1903047 194 0.136
Fly
translation GO:0006412 37 0.129
Fly
organelle organization GO:0006996 783 0.128
Human
cellular biosynthetic process GO:0044249 315 0.127
Human Fly
multicellular organism reproduction GO:0032504 819 0.125
regulation of vulval development GO:0040028 248 0.125
germ cell development GO:0007281 351 0.124
gonad development GO:0008406 840 0.124
transport GO:0006810 1093 0.123
regulation of multicellular organismal process GO:0051239 726 0.122
body morphogenesis GO:0010171 620 0.122
oviposition GO:0018991 364 0.119
cellular macromolecule biosynthetic process GO:0034645 247 0.119
Human Fly
cellular protein metabolic process GO:0044267 279 0.118
Fly
multi organism reproductive process GO:0044703 867 0.118
negative regulation of developmental process GO:0051093 227 0.117
Human
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.117
posttranscriptional regulation of gene expression GO:0010608 166 0.115
Fly
macromolecule biosynthetic process GO:0009059 250 0.114
Human Fly
regulation of nematode larval development GO:0061062 260 0.111
reproductive system development GO:0061458 850 0.109
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.108
Human Fly
head development GO:0060322 1 0.108
endocytosis GO:0006897 819 0.107
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.107
Human Fly
cellular component biogenesis GO:0044085 297 0.104
Human
regulation of cellular metabolic process GO:0031323 305 0.103
Human Fly
nucleic acid metabolic process GO:0090304 299 0.101
Human Fly
post embryonic organ development GO:0048569 336 0.101
nervous system development GO:0007399 253 0.098
heterocycle catabolic process GO:0046700 119 0.094
Fly
determination of adult lifespan GO:0008340 812 0.093
organic substance catabolic process GO:1901575 294 0.092
Fly
multicellular organismal aging GO:0010259 812 0.091
neurogenesis GO:0022008 236 0.090
cell motility GO:0048870 313 0.089
development of primary sexual characteristics GO:0045137 840 0.087
macromolecule localization GO:0033036 771 0.086
positive regulation of growth GO:0045927 369 0.086
female gamete generation GO:0007292 254 0.085
rna metabolic process GO:0016070 228 0.085
Human Fly
rna localization GO:0006403 3 0.084
cellular component movement GO:0006928 388 0.084
cellular catabolic process GO:0044248 199 0.082
Fly
muscle tissue development GO:0060537 1 0.082
regulation of mitotic cell cycle GO:0007346 76 0.081
Fly
regulation of stem cell differentiation GO:2000736 1 0.080
Human
striated muscle cell differentiation GO:0051146 158 0.077
cellular protein modification process GO:0006464 207 0.077
positive regulation of nucleic acid templated transcription GO:1903508 102 0.076
positive regulation of cellular process GO:0048522 332 0.076
Human
cell migration GO:0016477 306 0.076
oogenesis GO:0048477 229 0.074
regulation of developmental process GO:0050793 684 0.074
regulation of biological quality GO:0065008 741 0.073
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.072
behavior GO:0007610 527 0.071
single organism transport GO:0044765 447 0.070
multi organism behavior GO:0051705 389 0.069
negative regulation of vulval development GO:0040027 206 0.067
regulation of post embryonic development GO:0048580 260 0.067
cellular nitrogen compound catabolic process GO:0044270 119 0.066
Fly
establishment of localization in cell GO:0051649 318 0.065
muscle structure development GO:0061061 191 0.065
regulation of growth GO:0040008 409 0.064
regulation of multicellular organismal development GO:2000026 317 0.063
positive regulation of metabolic process GO:0009893 187 0.061
negative regulation of cellular protein metabolic process GO:0032269 27 0.061
Fly
lipid storage GO:0019915 565 0.061
growth GO:0040007 562 0.061
protein catabolic process GO:0030163 162 0.061
regulation of cellular biosynthetic process GO:0031326 189 0.060
Human Fly
maintenance of location GO:0051235 580 0.060
single organism organelle organization GO:1902589 501 0.060
localization of cell GO:0051674 313 0.059
positive regulation of cellular metabolic process GO:0031325 178 0.059
negative regulation of nematode larval development GO:0061064 208 0.058
multi multicellular organism process GO:0044706 390 0.058
positive regulation of cell cycle GO:0045787 55 0.058
lipid localization GO:0010876 573 0.056
negative regulation of gene expression GO:0010629 217 0.055
Human Fly
single fertilization GO:0007338 61 0.055
transcription dna templated GO:0006351 168 0.055
Human Fly
purine nucleotide catabolic process GO:0006195 75 0.054
negative regulation of protein metabolic process GO:0051248 27 0.053
Fly
cell cycle GO:0007049 526 0.053
Fly
cell morphogenesis GO:0000902 163 0.053
negative regulation of biosynthetic process GO:0009890 65 0.053
Human Fly
gtp catabolic process GO:0006184 46 0.053
negative regulation of post embryonic development GO:0048581 208 0.053
positive regulation of developmental growth GO:0048639 354 0.052
purine nucleoside triphosphate metabolic process GO:0009144 87 0.052
molting cycle GO:0042303 281 0.052
muscle cell differentiation GO:0042692 171 0.051
fertilization GO:0009566 63 0.051
meiotic cell cycle GO:0051321 335 0.051
single organism localization GO:1902578 518 0.051
protein complex subunit organization GO:0071822 280 0.051
cell development GO:0048468 696 0.051
Human
developmental growth GO:0048589 412 0.050
glycosyl compound metabolic process GO:1901657 100 0.050
signaling GO:0023052 401 0.050
Human Fly
organic substance biosynthetic process GO:1901576 323 0.049
Human Fly
epithelial tube morphogenesis GO:0060562 1 0.049
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.048
generation of neurons GO:0048699 235 0.047
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.047
cell death GO:0008219 547 0.046
regulation of locomotion GO:0040012 161 0.045
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.045
Human Fly
multicellular organism growth GO:0035264 385 0.045
establishment of mitotic spindle orientation GO:0000132 28 0.044
regulation of cellular protein metabolic process GO:0032268 75 0.044
Fly
biosynthetic process GO:0009058 323 0.044
Human Fly
positive regulation of multicellular organismal process GO:0051240 417 0.044
regulation of neuron differentiation GO:0045664 40 0.044
multicellular organismal reproductive behavior GO:0033057 384 0.043
rna processing GO:0006396 34 0.043
macromolecule modification GO:0043412 218 0.043
protein modification by small protein conjugation or removal GO:0070647 40 0.043
reproductive behavior GO:0019098 387 0.043
cellular macromolecule catabolic process GO:0044265 73 0.042
Fly
regulation of nitrogen compound metabolic process GO:0051171 222 0.042
Human Fly
regulation of cellular component organization GO:0051128 248 0.042
Human
purine nucleoside triphosphate catabolic process GO:0009146 72 0.042
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.042
cell cell signaling GO:0007267 118 0.041
Fly
cell cycle process GO:0022402 482 0.039
Fly
gene silencing by rna GO:0031047 143 0.038
positive regulation of multicellular organism growth GO:0040018 352 0.038
establishment of spindle localization GO:0051293 51 0.038
proteolysis GO:0006508 61 0.037
regulation of rna biosynthetic process GO:2001141 165 0.037
Human Fly
negative regulation of neurogenesis GO:0050768 4 0.037
ribonucleotide catabolic process GO:0009261 75 0.037
regulation of developmental growth GO:0048638 389 0.037
nucleoside triphosphate catabolic process GO:0009143 72 0.037
positive regulation of transcription dna templated GO:0045893 102 0.036
cell division GO:0051301 262 0.036
regulation of rna metabolic process GO:0051252 173 0.036
Human Fly
cellular localization GO:0051641 360 0.036
small molecule metabolic process GO:0044281 186 0.036
single organism signaling GO:0044700 401 0.035
Human Fly
meiotic nuclear division GO:0007126 300 0.035
ribonucleoside triphosphate catabolic process GO:0009203 72 0.035
purine containing compound catabolic process GO:0072523 75 0.035
protein localization GO:0008104 205 0.035
positive regulation of macromolecule metabolic process GO:0010604 149 0.034
aromatic compound catabolic process GO:0019439 116 0.034
Fly
gene silencing GO:0016458 143 0.034
anatomical structure formation involved in morphogenesis GO:0048646 250 0.034
regulation of protein metabolic process GO:0051246 81 0.034
Fly
establishment of cell polarity GO:0030010 46 0.034
posttranscriptional gene silencing GO:0016441 143 0.034
regulation of nucleic acid templated transcription GO:1903506 165 0.034
Human Fly
regulation of meiotic cell cycle GO:0051445 136 0.033
negative regulation of multicellular organismal process GO:0051241 236 0.033
regulation of cell cycle GO:0051726 194 0.032
Fly
cell fate commitment GO:0045165 139 0.032
Fly
purine ribonucleotide catabolic process GO:0009154 75 0.032
multi organism reproductive behavior GO:0044705 387 0.032
regulation of response to stimulus GO:0048583 243 0.032
Human
nucleotide catabolic process GO:0009166 77 0.032
response to chemical GO:0042221 356 0.032
positive regulation of developmental process GO:0051094 408 0.032
regulation of cell communication GO:0010646 176 0.031
Human
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.031
Human Fly
ribonucleoside triphosphate metabolic process GO:0009199 87 0.031
regulation of multicellular organism growth GO:0040014 373 0.031
regulation of localization GO:0032879 194 0.031
ribonucleoside catabolic process GO:0042454 77 0.030
aromatic compound biosynthetic process GO:0019438 192 0.030
Human Fly
regulation of signaling GO:0023051 172 0.030
Human
posttranscriptional gene silencing by rna GO:0035194 143 0.030
chemotaxis GO:0006935 120 0.030
purine ribonucleoside metabolic process GO:0046128 92 0.029
nucleic acid templated transcription GO:0097659 169 0.029
Human Fly
macromolecular complex subunit organization GO:0043933 320 0.028
Human
nucleotide metabolic process GO:0009117 108 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.028
cellular component morphogenesis GO:0032989 318 0.028
organonitrogen compound metabolic process GO:1901564 151 0.028
male gamete generation GO:0048232 41 0.028
spermatogenesis GO:0007283 41 0.028
cellular component assembly GO:0022607 293 0.028
Human
neuron differentiation GO:0030182 217 0.028
mitotic spindle organization GO:0007052 81 0.027
regulation of cell division GO:0051302 142 0.027
organophosphate catabolic process GO:0046434 81 0.027
establishment of mitotic spindle localization GO:0040001 41 0.026
regulation of transcription dna templated GO:0006355 164 0.025
Human Fly
carbohydrate derivative metabolic process GO:1901135 141 0.025
regulation of cellular component movement GO:0051270 62 0.025
neuron projection development GO:0031175 187 0.025
organelle localization GO:0051640 127 0.024
development of primary male sexual characteristics GO:0046546 4 0.024
purine containing compound metabolic process GO:0072521 95 0.024
modification dependent protein catabolic process GO:0019941 32 0.024
skeletal muscle organ development GO:0060538 3 0.024
single organism catabolic process GO:0044712 129 0.024
modification dependent macromolecule catabolic process GO:0043632 32 0.023
regulation of gene expression epigenetic GO:0040029 163 0.023
spindle localization GO:0051653 51 0.023
positive regulation of gene expression GO:0010628 112 0.023
actin filament based process GO:0030029 191 0.023
response to external stimulus GO:0009605 289 0.022
carbohydrate derivative catabolic process GO:1901136 82 0.022
positive regulation of neuron differentiation GO:0045666 4 0.022
nucleobase containing small molecule metabolic process GO:0055086 115 0.022
positive regulation of cell projection organization GO:0031346 4 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.022
ubiquitin dependent protein catabolic process GO:0006511 32 0.022
protein modification process GO:0036211 207 0.022
striated muscle cell development GO:0055002 157 0.022
cellular protein catabolic process GO:0044257 37 0.022
regulation of cell development GO:0060284 49 0.022
Human
nucleoside phosphate metabolic process GO:0006753 108 0.021
rna interference GO:0016246 137 0.021
ribose phosphate metabolic process GO:0019693 99 0.021
rna biosynthetic process GO:0032774 169 0.021
Human Fly
axon guidance GO:0007411 82 0.021
cytoskeleton organization GO:0007010 339 0.021
neuron development GO:0048666 199 0.021
cell proliferation GO:0008283 116 0.021
nucleoside catabolic process GO:0009164 78 0.021
establishment of spindle orientation GO:0051294 34 0.021
cell projection organization GO:0030030 231 0.021
epithelial cell proliferation GO:0050673 1 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.020
pattern specification process GO:0007389 59 0.020
ribonucleotide metabolic process GO:0009259 99 0.020
negative regulation of cellular metabolic process GO:0031324 95 0.020
Human Fly
phosphorus metabolic process GO:0006793 232 0.020
glycosyl compound catabolic process GO:1901658 79 0.020
establishment of organelle localization GO:0051656 123 0.019
regulation of cell fate commitment GO:0010453 22 0.019
programmed cell death GO:0012501 500 0.019
positive regulation of rna metabolic process GO:0051254 103 0.019
cellular nitrogen compound biosynthetic process GO:0044271 192 0.019
Human Fly
regulation of endocytosis GO:0030100 25 0.019
positive regulation of signaling GO:0023056 66 0.019
nucleoside triphosphate metabolic process GO:0009141 87 0.019
purine nucleotide metabolic process GO:0006163 95 0.019
organelle assembly GO:0070925 214 0.018
Human
cellular component assembly involved in morphogenesis GO:0010927 183 0.018
purine ribonucleoside catabolic process GO:0046130 75 0.018
intracellular receptor signaling pathway GO:0030522 2 0.018
Human
oocyte axis specification GO:0007309 2 0.018
nucleoside phosphate catabolic process GO:1901292 77 0.018
neuron projection guidance GO:0097485 82 0.018
spindle organization GO:0007051 92 0.018
heterocycle biosynthetic process GO:0018130 187 0.018
Human Fly
muscle cell development GO:0055001 158 0.018
gastrulation GO:0007369 58 0.018
mrna processing GO:0006397 13 0.018
protein complex biogenesis GO:0070271 186 0.018
ribonucleoside metabolic process GO:0009119 98 0.018
positive regulation of vulval development GO:0040026 52 0.018
regulation of gtp catabolic process GO:0033124 32 0.018
purine nucleoside catabolic process GO:0006152 75 0.018
regulation of apoptotic signaling pathway GO:2001233 1 0.017
engulfment of apoptotic cell GO:0043652 94 0.017
regulation of cell migration GO:0030334 55 0.017
positive regulation of catabolic process GO:0009896 38 0.017
actin cytoskeleton organization GO:0030036 184 0.017
regulation of mrna splicing via spliceosome GO:0048024 7 0.017
regulation of cell differentiation GO:0045595 81 0.017
Human
purine ribonucleotide metabolic process GO:0009150 95 0.016
positive regulation of neurogenesis GO:0050769 4 0.016
secretion GO:0046903 147 0.016
regulation of behavior GO:0050795 97 0.016
locomotory behavior GO:0007626 40 0.016
regulation of epithelial cell proliferation GO:0050678 1 0.016
regeneration GO:0031099 4 0.016
neuron projection morphogenesis GO:0048812 114 0.016
ribosome biogenesis GO:0042254 4 0.016
regulation of organelle organization GO:0033043 164 0.016
Human
mating GO:0007618 34 0.015
positive regulation of stem cell differentiation GO:2000738 1 0.015
organelle fission GO:0048285 363 0.015
regulation of axonogenesis GO:0050770 24 0.015
adult locomotory behavior GO:0008344 1 0.015
regulation of cell cycle process GO:0010564 145 0.015
Fly
digestive tract morphogenesis GO:0048546 76 0.015
organophosphate metabolic process GO:0019637 125 0.015
synaptic transmission GO:0007268 106 0.015
cell recognition GO:0008037 85 0.015
cell part morphogenesis GO:0032990 152 0.015
nucleobase containing compound biosynthetic process GO:0034654 184 0.014
Human Fly
myofibril assembly GO:0030239 154 0.014
nucleoside metabolic process GO:0009116 99 0.014
signal transduction GO:0007165 317 0.014
Human
phagocytosis engulfment GO:0006911 98 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.014
positive regulation of cellular biosynthetic process GO:0031328 109 0.014
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.014
striated muscle myosin thick filament assembly GO:0071688 138 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.014
macromolecular complex assembly GO:0065003 193 0.014
Human
cell morphogenesis involved in differentiation GO:0000904 112 0.014
dendrite development GO:0016358 42 0.014
cellular protein complex assembly GO:0043623 178 0.014
tube development GO:0035295 126 0.014
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.014
cell growth GO:0016049 44 0.014
sensory organ morphogenesis GO:0090596 2 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.014
Human
mrna metabolic process GO:0016071 31 0.014
Fly
negative regulation of cellular biosynthetic process GO:0031327 65 0.014
Human Fly
neuronal stem cell division GO:0036445 9 0.014
taxis GO:0042330 128 0.014
protein complex assembly GO:0006461 186 0.013
regulation of cell proliferation GO:0042127 105 0.013
asymmetric cell division GO:0008356 36 0.013
oocyte construction GO:0007308 2 0.013
purine nucleoside metabolic process GO:0042278 92 0.013
regulation of response to wounding GO:1903034 1 0.013
nitrogen compound transport GO:0071705 49 0.013
regulation of cell motility GO:2000145 57 0.013
chromatin remodeling GO:0006338 2 0.013
single organism behavior GO:0044708 83 0.013
positive regulation of biosynthetic process GO:0009891 109 0.013
regulation of transport GO:0051049 91 0.013
membrane invagination GO:0010324 98 0.013
regulation of organ morphogenesis GO:2000027 4 0.013
organic cyclic compound biosynthetic process GO:1901362 195 0.013
Human Fly
regulation of catalytic activity GO:0050790 78 0.013
myosin filament organization GO:0031033 138 0.013
intracellular transport GO:0046907 77 0.013
phagocytosis GO:0006909 115 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.012
oocyte differentiation GO:0009994 45 0.012
positive regulation of epithelial cell proliferation GO:0050679 1 0.012
regulation of synapse assembly GO:0051963 2 0.012
death GO:0016265 547 0.012
regulation of axon extension GO:0030516 20 0.012
positive regulation of phosphorus metabolic process GO:0010562 56 0.012
secretion by cell GO:0032940 138 0.012
regulation of signal transduction GO:0009966 135 0.012
Human
mrna catabolic process GO:0006402 16 0.012
Fly
microtubule based process GO:0007017 182 0.012
axonal fasciculation GO:0007413 79 0.012
establishment of nucleus localization GO:0040023 55 0.012
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 2 0.012
canonical wnt signaling pathway GO:0060070 3 0.012
establishment or maintenance of cell polarity GO:0007163 63 0.012
tissue development GO:0009888 112 0.012
meiotic cell cycle process GO:1903046 170 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.012
rna catabolic process GO:0006401 21 0.012
Fly
apical junction assembly GO:0043297 1 0.012
positive regulation of cell communication GO:0010647 69 0.012
muscle organ development GO:0007517 26 0.012
cellular response to unfolded protein GO:0034620 71 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
notch signaling pathway GO:0007219 22 0.011
translational initiation GO:0006413 2 0.011
response to wounding GO:0009611 4 0.011
muscle fiber development GO:0048747 2 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
axon development GO:0061564 163 0.011
positive regulation of meiotic cell cycle GO:0051446 47 0.011
digestive system development GO:0055123 122 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
myosin filament assembly GO:0031034 138 0.011
organic substance transport GO:0071702 113 0.011
regulation of rna splicing GO:0043484 7 0.011
organonitrogen compound catabolic process GO:1901565 90 0.011
signal release GO:0023061 28 0.011
phosphorylation GO:0016310 116 0.010
actomyosin structure organization GO:0031032 154 0.010
cellular response to stress GO:0033554 162 0.010
Fly
embryonic morphogenesis GO:0048598 152 0.010
mrna splice site selection GO:0006376 1 0.010
apoptotic process GO:0006915 478 0.010
meiotic chromosome segregation GO:0045132 139 0.010
positive regulation of rna biosynthetic process GO:1902680 102 0.010
regulation of canonical wnt signaling pathway GO:0060828 1 0.010

ntl-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.072
nervous system disease DOID:863 0 0.017
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012