Caenorhabditis elegans

26 known processes

apb-1 (CELE_Y71H2B.10)

Protein APB-1

apb-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organ development GO:0048513 1102 0.600
establishment of localization GO:0051234 1171 0.529
embryo development GO:0009790 3052 0.528
transport GO:0006810 1093 0.461
post embryonic development GO:0009791 2152 0.423
gonad development GO:0008406 840 0.415
embryo development ending in birth or egg hatching GO:0009792 2992 0.408
regulation of multicellular organismal process GO:0051239 726 0.365
body morphogenesis GO:0010171 620 0.348
receptor mediated endocytosis GO:0006898 715 0.345
locomotion GO:0040011 1634 0.343
development of primary sexual characteristics GO:0045137 840 0.343
neuron differentiation GO:0030182 217 0.310
generation of neurons GO:0048699 235 0.297
regulation of developmental process GO:0050793 684 0.291
cell development GO:0048468 696 0.288
developmental process involved in reproduction GO:0003006 1165 0.259
negative regulation of biological process GO:0048519 567 0.257
single organism reproductive process GO:0044702 1196 0.253
establishment of localization in cell GO:0051649 318 0.244
reproductive structure development GO:0048608 850 0.243
neuron development GO:0048666 199 0.239
neurogenesis GO:0022008 236 0.232
neuron projection development GO:0031175 187 0.224
reproductive system development GO:0061458 850 0.223
single organism localization GO:1902578 518 0.212
tube morphogenesis GO:0035239 79 0.211
growth GO:0040007 562 0.210
genitalia development GO:0048806 741 0.204
vesicle mediated transport GO:0016192 852 0.190
cell projection organization GO:0030030 231 0.184
protein complex subunit organization GO:0071822 280 0.180
nervous system development GO:0007399 253 0.175
endocytosis GO:0006897 819 0.160
positive regulation of cellular process GO:0048522 332 0.154
regulation of macromolecule metabolic process GO:0060255 421 0.153
cellular component biogenesis GO:0044085 297 0.152
embryonic morphogenesis GO:0048598 152 0.152
sexual reproduction GO:0019953 546 0.150
negative regulation of gene expression GO:0010629 217 0.148
regulation of multicellular organismal development GO:2000026 317 0.146
epithelial tube morphogenesis GO:0060562 1 0.128
single organism transport GO:0044765 447 0.126
cell migration GO:0016477 306 0.126
regulation of neuron differentiation GO:0045664 40 0.125
nucleobase containing compound catabolic process GO:0034655 114 0.121
cell death GO:0008219 547 0.119
secretion GO:0046903 147 0.118
regulation of growth GO:0040008 409 0.118
hermaphrodite genitalia development GO:0040035 734 0.116
macromolecular complex subunit organization GO:0043933 320 0.115
behavior GO:0007610 527 0.115
cellular component morphogenesis GO:0032989 318 0.114
death GO:0016265 547 0.112
negative regulation of metabolic process GO:0009892 240 0.110
axon development GO:0061564 163 0.110
secretion by cell GO:0032940 138 0.106
developmental growth GO:0048589 412 0.103
sex differentiation GO:0007548 909 0.099
protein complex assembly GO:0006461 186 0.098
regulation of metabolic process GO:0019222 478 0.097
cell cycle process GO:0022402 482 0.095
multicellular organismal aging GO:0010259 812 0.093
organelle organization GO:0006996 783 0.092
multicellular organism reproduction GO:0032504 819 0.091
tube development GO:0035295 126 0.091
macromolecule localization GO:0033036 771 0.090
embryonic body morphogenesis GO:0010172 49 0.090
regulation of biological quality GO:0065008 741 0.089
negative regulation of cellular process GO:0048523 239 0.089
negative regulation of developmental process GO:0051093 227 0.088
germ cell development GO:0007281 351 0.087
cellular localization GO:0051641 360 0.086
signal transduction GO:0007165 317 0.084
regulation of multicellular organism growth GO:0040014 373 0.083
protein metabolic process GO:0019538 422 0.083
organic substance catabolic process GO:1901575 294 0.080
programmed cell death GO:0012501 500 0.079
cell cycle GO:0007049 526 0.077
single organism organelle organization GO:1902589 501 0.076
nucleobase containing compound metabolic process GO:0006139 406 0.076
cell morphogenesis GO:0000902 163 0.075
multicellular organism growth GO:0035264 385 0.075
cell cell signaling GO:0007267 118 0.074
cellular protein complex assembly GO:0043623 178 0.072
tissue development GO:0009888 112 0.072
aging GO:0007568 812 0.071
cellular component assembly GO:0022607 293 0.070
gene expression GO:0010467 412 0.070
positive regulation of multicellular organism growth GO:0040018 352 0.069
anatomical structure formation involved in morphogenesis GO:0048646 250 0.069
positive regulation of growth GO:0045927 369 0.069
purine containing compound catabolic process GO:0072523 75 0.068
positive regulation of multicellular organismal process GO:0051240 417 0.068
regulation of locomotion GO:0040012 161 0.068
positive regulation of developmental process GO:0051094 408 0.068
catabolic process GO:0009056 318 0.068
protein complex biogenesis GO:0070271 186 0.067
multi organism reproductive process GO:0044703 867 0.065
multicellular organismal reproductive process GO:0048609 815 0.064
nucleic acid metabolic process GO:0090304 299 0.064
single organism signaling GO:0044700 401 0.063
macromolecular complex assembly GO:0065003 193 0.063
gamete generation GO:0007276 461 0.063
regulation of localization GO:0032879 194 0.062
cell proliferation GO:0008283 116 0.061
lipid storage GO:0019915 565 0.059
determination of adult lifespan GO:0008340 812 0.058
purine ribonucleotide metabolic process GO:0009150 95 0.057
positive regulation of locomotion GO:0040017 42 0.057
lipid localization GO:0010876 573 0.057
maintenance of location GO:0051235 580 0.057
macromolecule catabolic process GO:0009057 202 0.057
response to abiotic stimulus GO:0009628 152 0.057
cell junction organization GO:0034330 18 0.056
organ morphogenesis GO:0009887 67 0.056
nucleotide metabolic process GO:0009117 108 0.056
regulation of transport GO:0051049 91 0.056
head development GO:0060322 1 0.056
sensory organ morphogenesis GO:0090596 2 0.056
negative regulation of macromolecule metabolic process GO:0010605 229 0.055
protein catabolic process GO:0030163 162 0.055
taxis GO:0042330 128 0.055
positive regulation of synaptic transmission GO:0050806 24 0.055
apoptotic process GO:0006915 478 0.054
cellular macromolecular complex assembly GO:0034622 184 0.054
heterocycle catabolic process GO:0046700 119 0.054
female gamete generation GO:0007292 254 0.054
aromatic compound catabolic process GO:0019439 116 0.054
regulation of developmental growth GO:0048638 389 0.053
response to external stimulus GO:0009605 289 0.053
signaling GO:0023052 401 0.052
regulation of cell division GO:0051302 142 0.052
muscle structure development GO:0061061 191 0.052
small molecule metabolic process GO:0044281 186 0.052
endosomal transport GO:0016197 26 0.051
neuron projection morphogenesis GO:0048812 114 0.050
response to chemical GO:0042221 356 0.048
glycosyl compound catabolic process GO:1901658 79 0.048
cellular protein metabolic process GO:0044267 279 0.048
organic cyclic compound catabolic process GO:1901361 119 0.047
regulation of cell communication GO:0010646 176 0.047
organelle fission GO:0048285 363 0.047
cellular nitrogen compound catabolic process GO:0044270 119 0.047
cellular catabolic process GO:0044248 199 0.046
protein localization GO:0008104 205 0.045
multi organism behavior GO:0051705 389 0.045
regulation of signal transduction GO:0009966 135 0.045
digestive tract development GO:0048565 122 0.045
neuron projection guidance GO:0097485 82 0.045
mrna catabolic process GO:0006402 16 0.045
epithelium development GO:0060429 68 0.044
posttranscriptional gene silencing GO:0016441 143 0.044
axon guidance GO:0007411 82 0.044
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.044
regulation of cell cycle process GO:0010564 145 0.044
cell part morphogenesis GO:0032990 152 0.043
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.043
purine ribonucleoside catabolic process GO:0046130 75 0.043
regulation of rna metabolic process GO:0051252 173 0.043
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.042
system process GO:0003008 136 0.042
regulation of cell morphogenesis GO:0022604 40 0.042
ribonucleoprotein complex assembly GO:0022618 4 0.042
rna metabolic process GO:0016070 228 0.041
golgi vesicle transport GO:0048193 3 0.041
nucleoside metabolic process GO:0009116 99 0.041
guanosine containing compound catabolic process GO:1901069 48 0.041
inductive cell migration GO:0040039 145 0.041
cell division GO:0051301 262 0.041
regulation of cellular component organization GO:0051128 248 0.040
neuromuscular junction development GO:0007528 2 0.040
molting cycle GO:0042303 281 0.040
neurotransmitter transport GO:0006836 32 0.040
organophosphate metabolic process GO:0019637 125 0.039
positive regulation of neurogenesis GO:0050769 4 0.039
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.039
cytoskeleton organization GO:0007010 339 0.038
oviposition GO:0018991 364 0.037
purine nucleoside triphosphate catabolic process GO:0009146 72 0.037
multi organism reproductive behavior GO:0044705 387 0.037
pattern specification process GO:0007389 59 0.037
posttranscriptional regulation of gene expression GO:0010608 166 0.037
reproductive behavior GO:0019098 387 0.037
biosynthetic process GO:0009058 323 0.037
negative regulation of nematode larval development GO:0061064 208 0.037
positive regulation of developmental growth GO:0048639 354 0.037
organonitrogen compound metabolic process GO:1901564 151 0.036
regulation of cell cycle GO:0051726 194 0.036
organophosphate catabolic process GO:0046434 81 0.035
negative regulation of post embryonic development GO:0048581 208 0.035
negative regulation of multicellular organismal process GO:0051241 236 0.035
mitotic nuclear division GO:0007067 89 0.035
purine nucleoside metabolic process GO:0042278 92 0.035
regulation of cell proliferation GO:0042127 105 0.034
purine nucleoside catabolic process GO:0006152 75 0.034
intracellular signal transduction GO:0035556 96 0.034
cytokinesis GO:0000910 80 0.034
regulation of cellular metabolic process GO:0031323 305 0.033
regulation of gene expression GO:0010468 366 0.033
organic cyclic compound biosynthetic process GO:1901362 195 0.033
organelle assembly GO:0070925 214 0.033
chemotaxis GO:0006935 120 0.032
digestive system development GO:0055123 122 0.032
regulation of response to stimulus GO:0048583 243 0.032
cell motility GO:0048870 313 0.032
purine ribonucleoside metabolic process GO:0046128 92 0.032
phosphate containing compound metabolic process GO:0006796 232 0.031
nucleoside catabolic process GO:0009164 78 0.031
protein modification process GO:0036211 207 0.031
transcription dna templated GO:0006351 168 0.031
oogenesis GO:0048477 229 0.031
nucleoside triphosphate metabolic process GO:0009141 87 0.030
regulation of cell differentiation GO:0045595 81 0.030
regulation of stem cell differentiation GO:2000736 1 0.030
single fertilization GO:0007338 61 0.029
multi multicellular organism process GO:0044706 390 0.029
striated muscle cell differentiation GO:0051146 158 0.029
nucleoside phosphate metabolic process GO:0006753 108 0.029
ribonucleotide catabolic process GO:0009261 75 0.029
cell projection morphogenesis GO:0048858 148 0.028
rna interference GO:0016246 137 0.028
small gtpase mediated signal transduction GO:0007264 32 0.028
regulation of intracellular signal transduction GO:1902531 77 0.028
membrane organization GO:0061024 135 0.028
purine nucleoside triphosphate metabolic process GO:0009144 87 0.028
regulation of primary metabolic process GO:0080090 292 0.027
posttranscriptional gene silencing by rna GO:0035194 143 0.027
purine nucleotide metabolic process GO:0006163 95 0.027
localization of cell GO:0051674 313 0.027
response to organic substance GO:0010033 131 0.027
multicellular organismal reproductive behavior GO:0033057 384 0.027
skeletal muscle organ development GO:0060538 3 0.027
actin filament based process GO:0030029 191 0.027
negative regulation of vulval development GO:0040027 206 0.027
purine containing compound metabolic process GO:0072521 95 0.027
purine nucleotide catabolic process GO:0006195 75 0.027
ribonucleoside catabolic process GO:0042454 77 0.027
aromatic compound biosynthetic process GO:0019438 192 0.026
response to wounding GO:0009611 4 0.026
nucleobase containing small molecule metabolic process GO:0055086 115 0.026
myofibril assembly GO:0030239 154 0.026
microtubule based process GO:0007017 182 0.026
single organism behavior GO:0044708 83 0.026
meiotic cell cycle GO:0051321 335 0.026
cellular macromolecule biosynthetic process GO:0034645 247 0.026
cellular component movement GO:0006928 388 0.025
regulation of endocytosis GO:0030100 25 0.025
actomyosin structure organization GO:0031032 154 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.025
cellular response to organic substance GO:0071310 119 0.025
dauer larval development GO:0040024 92 0.024
nucleotide catabolic process GO:0009166 77 0.024
regulation of signaling GO:0023051 172 0.024
regulation of gene expression epigenetic GO:0040029 163 0.024
myosin filament assembly GO:0031034 138 0.024
ribonucleoside metabolic process GO:0009119 98 0.024
ribonucleoside triphosphate catabolic process GO:0009203 72 0.024
cell type specific apoptotic process GO:0097285 4 0.024
response to temperature stimulus GO:0009266 66 0.024
gene silencing by rna GO:0031047 143 0.023
cell surface receptor signaling pathway GO:0007166 149 0.023
ribose phosphate metabolic process GO:0019693 99 0.023
positive regulation of transport GO:0051050 32 0.023
actin cytoskeleton organization GO:0030036 184 0.023
establishment of organelle localization GO:0051656 123 0.023
glycosyl compound metabolic process GO:1901657 100 0.022
single organism cellular localization GO:1902580 72 0.022
defense response GO:0006952 296 0.022
regulation of nematode larval development GO:0061062 260 0.022
regulation of post embryonic development GO:0048580 260 0.022
post embryonic organ development GO:0048569 336 0.021
cellular response to stress GO:0033554 162 0.021
muscle cell differentiation GO:0042692 171 0.021
single organism catabolic process GO:0044712 129 0.021
ion transport GO:0006811 113 0.021
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.021
negative regulation of signal transduction GO:0009968 60 0.021
rna localization GO:0006403 3 0.021
heterocycle biosynthetic process GO:0018130 187 0.021
cell morphogenesis involved in differentiation GO:0000904 112 0.021
tissue morphogenesis GO:0048729 65 0.020
positive regulation of metabolic process GO:0009893 187 0.020
cellular protein modification process GO:0006464 207 0.020
regulation of multi organism process GO:0043900 69 0.020
oocyte axis specification GO:0007309 2 0.020
muscle cell development GO:0055001 158 0.020
meiotic cell cycle process GO:1903046 170 0.020
regulation of vulval development GO:0040028 248 0.020
negative regulation of cellular metabolic process GO:0031324 95 0.019
organic substance biosynthetic process GO:1901576 323 0.019
carbohydrate derivative metabolic process GO:1901135 141 0.019
organonitrogen compound catabolic process GO:1901565 90 0.019
striated muscle myosin thick filament assembly GO:0071688 138 0.019
ribonucleoside triphosphate metabolic process GO:0009199 87 0.019
meiotic nuclear division GO:0007126 300 0.018
negative regulation of cellular biosynthetic process GO:0031327 65 0.018
regulation of neurotransmitter secretion GO:0046928 16 0.018
regulation of catalytic activity GO:0050790 78 0.018
regulation of hydrolase activity GO:0051336 45 0.018
macromolecule biosynthetic process GO:0009059 250 0.018
fertilization GO:0009566 63 0.018
negative regulation of response to stimulus GO:0048585 73 0.018
protein oligomerization GO:0051259 4 0.017
purine ribonucleotide catabolic process GO:0009154 75 0.017
notch signaling pathway GO:0007219 22 0.017
regulation of nervous system development GO:0051960 41 0.017
axonal fasciculation GO:0007413 79 0.017
axonogenesis GO:0007409 102 0.017
positive regulation of secretion GO:0051047 17 0.017
cell substrate adhesion GO:0031589 1 0.017
synaptic transmission GO:0007268 106 0.017
gene silencing GO:0016458 143 0.017
regulation of cell development GO:0060284 49 0.017
nucleoside triphosphate catabolic process GO:0009143 72 0.017
ribonucleotide metabolic process GO:0009259 99 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
regulation of mitosis GO:0007088 18 0.017
cellular biosynthetic process GO:0044249 315 0.016
memory GO:0007613 3 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
oocyte construction GO:0007308 2 0.016
regulation of molecular function GO:0065009 89 0.016
regulation of neurotransmitter levels GO:0001505 36 0.016
guanosine containing compound metabolic process GO:1901068 49 0.016
regulation of vesicle mediated transport GO:0060627 27 0.016
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.016
positive regulation of signaling GO:0023056 66 0.016
mrna metabolic process GO:0016071 31 0.016
cellular component assembly involved in morphogenesis GO:0010927 183 0.016
regulation of apoptotic signaling pathway GO:2001233 1 0.016
cellular macromolecule catabolic process GO:0044265 73 0.016
regulation of organ morphogenesis GO:2000027 4 0.016
regulation of synaptic transmission GO:0050804 34 0.016
regulation of organelle organization GO:0033043 164 0.016
mitotic cell cycle process GO:1903047 194 0.015
cellular amine metabolic process GO:0044106 15 0.015
regulation of anatomical structure morphogenesis GO:0022603 51 0.015
regionalization GO:0003002 31 0.015
phagocytosis GO:0006909 115 0.015
positive regulation of nucleotide catabolic process GO:0030813 28 0.015
neuron recognition GO:0008038 83 0.015
neurotransmitter secretion GO:0007269 26 0.015
regulation of nuclear division GO:0051783 115 0.015
ras protein signal transduction GO:0007265 31 0.015
positive regulation of cell communication GO:0010647 69 0.015
negative regulation of rna biosynthetic process GO:1902679 53 0.014
positive regulation of secretion by cell GO:1903532 14 0.014
collagen and cuticulin based cuticle development GO:0040002 99 0.014
canonical wnt signaling pathway GO:0060070 3 0.014
cuticle development GO:0042335 100 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.014
negative regulation of cell communication GO:0010648 61 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
dendrite development GO:0016358 42 0.013
positive regulation of nucleoside metabolic process GO:0045979 28 0.013
regulation of nitrogen compound metabolic process GO:0051171 222 0.013
establishment of protein localization GO:0045184 50 0.013
cellular response to chemical stimulus GO:0070887 129 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
regulation of secretion by cell GO:1903530 21 0.013
vulval development GO:0040025 333 0.013
cellular amino acid metabolic process GO:0006520 15 0.013
vesicle localization GO:0051648 24 0.013
innate immune response GO:0045087 190 0.013
regeneration GO:0031099 4 0.013
g protein coupled receptor signaling pathway GO:0007186 46 0.012
regulation of transcription dna templated GO:0006355 164 0.012
carbohydrate derivative catabolic process GO:1901136 82 0.012
striated muscle cell development GO:0055002 157 0.012
nitrogen compound transport GO:0071705 49 0.012
digestive tract morphogenesis GO:0048546 76 0.012
nucleoside phosphate catabolic process GO:1901292 77 0.012
pole plasm assembly GO:0007315 2 0.012
regulation of cell death GO:0010941 65 0.012
regulation of neurogenesis GO:0050767 40 0.012
response to heat GO:0009408 50 0.012
regulation of meiotic cell cycle GO:0051445 136 0.012
regulation of filopodium assembly GO:0051489 2 0.012
meiotic chromosome segregation GO:0045132 139 0.012
regulation of cellular component movement GO:0051270 62 0.012
macromolecule modification GO:0043412 218 0.012
regulation of phosphorus metabolic process GO:0051174 81 0.012
gtp metabolic process GO:0046039 46 0.012
phosphorylation GO:0016310 116 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.011
regulation of nucleoside metabolic process GO:0009118 37 0.011
oxoacid metabolic process GO:0043436 47 0.011
pigmentation GO:0043473 2 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.011
organic acid metabolic process GO:0006082 47 0.011
muscle fiber development GO:0048747 2 0.011
phosphorus metabolic process GO:0006793 232 0.011
establishment of protein localization to membrane GO:0090150 3 0.011
regulation of macromolecule biosynthetic process GO:0010556 189 0.011
regulation of catabolic process GO:0009894 57 0.011
myosin filament organization GO:0031033 138 0.011
carbohydrate metabolic process GO:0005975 34 0.011
gtp catabolic process GO:0006184 46 0.011
positive regulation of catabolic process GO:0009896 38 0.011
regulation of cellular protein metabolic process GO:0032268 75 0.011
negative regulation of rna metabolic process GO:0051253 53 0.011
cell growth GO:0016049 44 0.011
regulation of embryonic development GO:0045995 16 0.011
single organism membrane organization GO:0044802 35 0.011
negative regulation of biosynthetic process GO:0009890 65 0.011
regulation of ion transport GO:0043269 39 0.011
regulation of cell migration GO:0030334 55 0.011
necrotic cell death GO:0070265 29 0.010
regulation of cellular biosynthetic process GO:0031326 189 0.010
homeostatic process GO:0042592 51 0.010
regulation of programmed cell death GO:0043067 50 0.010
regulation of lipid metabolic process GO:0019216 4 0.010
signal release GO:0023061 28 0.010
amine metabolic process GO:0009308 15 0.010
negative regulation of translation GO:0017148 10 0.010
carboxylic acid metabolic process GO:0019752 34 0.010
positive regulation of cellular metabolic process GO:0031325 178 0.010
positive regulation of response to stimulus GO:0048584 55 0.010
regulation of phosphate metabolic process GO:0019220 81 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 28 0.010
response to topologically incorrect protein GO:0035966 82 0.010
organic substance transport GO:0071702 113 0.010
membrane invagination GO:0010324 98 0.010
regulation of rna biosynthetic process GO:2001141 165 0.010

apb-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.084
nervous system disease DOID:863 0 0.026