Caenorhabditis elegans

29 known processes

efl-2 (CELE_Y48C3A.17)

Protein EFL-2

efl-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.218
Worm
organ development GO:0048513 1102 0.213
post embryonic organ development GO:0048569 336 0.200
multicellular organism reproduction GO:0032504 819 0.192
Worm Fly
regulation of multicellular organismal process GO:0051239 726 0.169
regulation of post embryonic development GO:0048580 260 0.167
regulation of nematode larval development GO:0061062 260 0.145
post embryonic development GO:0009791 2152 0.144
negative regulation of post embryonic development GO:0048581 208 0.144
negative regulation of nematode larval development GO:0061064 208 0.129
regulation of vulval development GO:0040028 248 0.125
multicellular organismal reproductive process GO:0048609 815 0.108
Worm Fly
multi organism reproductive process GO:0044703 867 0.105
Worm Fly
locomotion GO:0040011 1634 0.099
multi multicellular organism process GO:0044706 390 0.099
behavior GO:0007610 527 0.099
embryo development ending in birth or egg hatching GO:0009792 2992 0.095
Worm
positive regulation of cellular process GO:0048522 332 0.086
Human Mouse Fly
regulation of biological quality GO:0065008 741 0.085
Human
neuron projection development GO:0031175 187 0.084
Fly
vulval development GO:0040025 333 0.084
regulation of developmental process GO:0050793 684 0.084
reproductive structure development GO:0048608 850 0.083
oviposition GO:0018991 364 0.082
regulation of multicellular organismal development GO:2000026 317 0.080
single organism reproductive process GO:0044702 1196 0.080
Worm Fly
cellular component morphogenesis GO:0032989 318 0.079
Fly
negative regulation of biological process GO:0048519 567 0.077
reproductive behavior GO:0019098 387 0.077
transport GO:0006810 1093 0.076
positive regulation of rna metabolic process GO:0051254 103 0.076
Human Mouse Fly
developmental process involved in reproduction GO:0003006 1165 0.076
Fly
single organism transport GO:0044765 447 0.075
multi organism behavior GO:0051705 389 0.074
regulation of cellular biosynthetic process GO:0031326 189 0.073
Human Mouse Fly
multi organism reproductive behavior GO:0044705 387 0.073
cellular component movement GO:0006928 388 0.072
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.071
signaling GO:0023052 401 0.069
Human Mouse Worm
positive regulation of rna biosynthetic process GO:1902680 102 0.068
Human Mouse Fly
cell development GO:0048468 696 0.068
Fly
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.068
Human Mouse Fly
regulation of metabolic process GO:0019222 478 0.068
Human Mouse Fly
reproductive system development GO:0061458 850 0.065
aging GO:0007568 812 0.065
regulation of multicellular organism growth GO:0040014 373 0.064
development of primary sexual characteristics GO:0045137 840 0.063
establishment of localization GO:0051234 1171 0.062
positive regulation of developmental process GO:0051094 408 0.062
Fly
regulation of cell communication GO:0010646 176 0.061
Worm
maintenance of location GO:0051235 580 0.060
macromolecule localization GO:0033036 771 0.060
determination of adult lifespan GO:0008340 812 0.059
regulation of cellular metabolic process GO:0031323 305 0.058
Human Mouse Fly
multicellular organism growth GO:0035264 385 0.058
multicellular organismal reproductive behavior GO:0033057 384 0.058
lipid storage GO:0019915 565 0.057
lipid localization GO:0010876 573 0.057
protein metabolic process GO:0019538 422 0.056
positive regulation of multicellular organism growth GO:0040018 352 0.056
regulation of developmental growth GO:0048638 389 0.056
body morphogenesis GO:0010171 620 0.056
regulation of response to stimulus GO:0048583 243 0.055
Worm
nucleobase containing compound metabolic process GO:0006139 406 0.054
Human Mouse Fly
regulation of macromolecule biosynthetic process GO:0010556 189 0.053
Human Mouse Fly
regulation of biosynthetic process GO:0009889 189 0.053
Human Mouse Fly
sex differentiation GO:0007548 909 0.053
positive regulation of multicellular organismal process GO:0051240 417 0.053
Fly
regulation of locomotion GO:0040012 161 0.052
regulation of cellular component organization GO:0051128 248 0.051
negative regulation of macromolecule metabolic process GO:0010605 229 0.050
Human Fly
nervous system development GO:0007399 253 0.050
Mouse Fly
growth GO:0040007 562 0.048
cellular macromolecule biosynthetic process GO:0034645 247 0.047
Human Mouse Fly
tissue development GO:0009888 112 0.047
Fly
single organism signaling GO:0044700 401 0.046
Human Mouse Worm
positive regulation of growth GO:0045927 369 0.046
positive regulation of transcription dna templated GO:0045893 102 0.046
Human Mouse Fly
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.046
Human Mouse Fly
multicellular organismal aging GO:0010259 812 0.046
vesicle mediated transport GO:0016192 852 0.045
positive regulation of macromolecule metabolic process GO:0010604 149 0.045
Human Mouse Fly
genitalia development GO:0048806 741 0.045
gonad development GO:0008406 840 0.045
response to external stimulus GO:0009605 289 0.044
Fly
macromolecule biosynthetic process GO:0009059 250 0.044
Human Mouse Fly
ion transport GO:0006811 113 0.042
positive regulation of cellular metabolic process GO:0031325 178 0.042
Human Mouse Fly
cation transport GO:0006812 78 0.042
regulation of primary metabolic process GO:0080090 292 0.042
Human Mouse Fly
regulation of gene expression GO:0010468 366 0.042
Human Mouse Fly
single organism localization GO:1902578 518 0.041
cell part morphogenesis GO:0032990 152 0.041
Fly
response to chemical GO:0042221 356 0.041
developmental growth GO:0048589 412 0.041
positive regulation of biosynthetic process GO:0009891 109 0.040
Human Mouse Fly
regulation of signal transduction GO:0009966 135 0.040
Worm
cell morphogenesis involved in differentiation GO:0000904 112 0.040
Fly
gene expression GO:0010467 412 0.040
Human Mouse Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.039
Human Mouse Fly
cell motility GO:0048870 313 0.039
neurogenesis GO:0022008 236 0.038
Fly
organic substance catabolic process GO:1901575 294 0.038
positive regulation of developmental growth GO:0048639 354 0.038
head development GO:0060322 1 0.038
Mouse
ion transmembrane transport GO:0034220 91 0.038
negative regulation of metabolic process GO:0009892 240 0.037
Human Fly
neuron development GO:0048666 199 0.037
Fly
regulation of localization GO:0032879 194 0.037
catabolic process GO:0009056 318 0.037
molting cycle GO:0042303 281 0.036
nucleic acid templated transcription GO:0097659 169 0.035
Human Mouse Fly
response to other organism GO:0051707 101 0.035
Fly
hermaphrodite genitalia development GO:0040035 734 0.035
cuticle development GO:0042335 100 0.035
regulation of growth GO:0040008 409 0.035
cellular component assembly GO:0022607 293 0.035
cellular biosynthetic process GO:0044249 315 0.035
Human Mouse Fly
organic cyclic compound biosynthetic process GO:1901362 195 0.034
Human Mouse Fly
organelle organization GO:0006996 783 0.033
single organism organelle organization GO:1902589 501 0.033
transmembrane transport GO:0055085 110 0.033
organic substance biosynthetic process GO:1901576 323 0.032
Human Mouse Fly
nucleic acid metabolic process GO:0090304 299 0.032
Human Mouse Fly
muscle cell differentiation GO:0042692 171 0.032
collagen and cuticulin based cuticle development GO:0040002 99 0.032
cell fate commitment GO:0045165 139 0.031
localization of cell GO:0051674 313 0.031
positive regulation of locomotion GO:0040017 42 0.031
cation transmembrane transport GO:0098655 59 0.031
negative regulation of gene expression GO:0010629 217 0.031
Human Fly
regulation of macromolecule metabolic process GO:0060255 421 0.030
Human Mouse Fly
regulation of rna metabolic process GO:0051252 173 0.030
Human Mouse Fly
neuron differentiation GO:0030182 217 0.030
Fly
aromatic compound biosynthetic process GO:0019438 192 0.030
Human Mouse Fly
protein catabolic process GO:0030163 162 0.029
signal transduction GO:0007165 317 0.029
Human Mouse Worm
negative regulation of developmental process GO:0051093 227 0.029
defense response GO:0006952 296 0.029
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.029
Human Mouse Fly
regulation of signaling GO:0023051 172 0.028
Worm
transcription from rna polymerase ii promoter GO:0006366 149 0.028
Human Mouse Fly
receptor mediated endocytosis GO:0006898 715 0.028
cell projection organization GO:0030030 231 0.028
Fly
regulation of rna biosynthetic process GO:2001141 165 0.027
Human Mouse Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.027
Human Mouse Fly
regulation of behavior GO:0050795 97 0.027
heterocycle biosynthetic process GO:0018130 187 0.026
Human Mouse Fly
negative regulation of multicellular organismal process GO:0051241 236 0.026
homeostatic process GO:0042592 51 0.026
regulation of nucleic acid templated transcription GO:1903506 165 0.026
Human Mouse Fly
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.025
Human Mouse Fly
rna metabolic process GO:0016070 228 0.025
Human Mouse Fly
system process GO:0003008 136 0.025
embryonic morphogenesis GO:0048598 152 0.025
Worm
transcription dna templated GO:0006351 168 0.025
Human Mouse Fly
cell migration GO:0016477 306 0.024
regulation of reproductive process GO:2000241 66 0.024
Fly
positive regulation of metabolic process GO:0009893 187 0.023
Human Mouse Fly
regulation of transcription dna templated GO:0006355 164 0.023
Human Mouse Fly
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.023
Fly
endocytosis GO:0006897 819 0.022
protein complex subunit organization GO:0071822 280 0.022
eating behavior GO:0042755 59 0.022
cell morphogenesis GO:0000902 163 0.022
Fly
cellular component assembly involved in morphogenesis GO:0010927 183 0.022
epithelium development GO:0060429 68 0.022
response to organic substance GO:0010033 131 0.022
programmed cell death GO:0012501 500 0.021
Human Mouse Fly
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.021
Human Fly
muscle tissue development GO:0060537 1 0.021
Fly
generation of neurons GO:0048699 235 0.021
Fly
macromolecular complex subunit organization GO:0043933 320 0.021
cell death GO:0008219 547 0.020
Human Mouse Fly
cellular component biogenesis GO:0044085 297 0.020
negative regulation of vulval development GO:0040027 206 0.020
positive regulation of gene expression GO:0010628 112 0.020
Human Mouse Fly
macromolecule catabolic process GO:0009057 202 0.019
muscle system process GO:0003012 43 0.019
muscle structure development GO:0061061 191 0.019
response to biotic stimulus GO:0009607 101 0.019
Fly
striated muscle cell differentiation GO:0051146 158 0.019
negative regulation of cellular process GO:0048523 239 0.018
Human Worm Fly
cellular nitrogen compound biosynthetic process GO:0044271 192 0.018
Human Mouse Fly
posttranscriptional regulation of gene expression GO:0010608 166 0.017
Human
regulation of nitrogen compound metabolic process GO:0051171 222 0.017
Human Mouse Fly
intracellular receptor signaling pathway GO:0030522 2 0.017
cytoskeleton organization GO:0007010 339 0.017
negative regulation of cellular metabolic process GO:0031324 95 0.016
Human Fly
cell cycle process GO:0022402 482 0.016
Human Mouse Fly
actin cytoskeleton organization GO:0030036 184 0.016
negative regulation of cellular biosynthetic process GO:0031327 65 0.016
Human Fly
small molecule metabolic process GO:0044281 186 0.016
organelle assembly GO:0070925 214 0.016
death GO:0016265 547 0.016
Human Mouse Fly
organic cyclic compound catabolic process GO:1901361 119 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.016
Human Mouse Fly
regulation of cell differentiation GO:0045595 81 0.015
Fly
anatomical structure formation involved in morphogenesis GO:0048646 250 0.015
response to external biotic stimulus GO:0043207 101 0.015
Fly
acetylcholine transport GO:0015870 16 0.015
actin filament based process GO:0030029 191 0.015
adult behavior GO:0030534 3 0.015
biosynthetic process GO:0009058 323 0.015
Human Mouse Fly
organonitrogen compound metabolic process GO:1901564 151 0.015
organic substance transport GO:0071702 113 0.015
positive regulation of nucleic acid templated transcription GO:1903508 102 0.015
Human Mouse Fly
nucleobase containing compound biosynthetic process GO:0034654 184 0.015
Human Mouse Fly
axon development GO:0061564 163 0.015
rna interference GO:0016246 137 0.014
muscle cell development GO:0055001 158 0.014
cellular catabolic process GO:0044248 199 0.014
striated muscle cell development GO:0055002 157 0.014
regulation of multi organism process GO:0043900 69 0.014
Fly
cell cell signaling GO:0007267 118 0.014
single organism catabolic process GO:0044712 129 0.014
posttranscriptional gene silencing by rna GO:0035194 143 0.014
regulation of cell cycle GO:0051726 194 0.014
Human Mouse Fly
metal ion transport GO:0030001 49 0.014
cell proliferation GO:0008283 116 0.014
Human Mouse Fly
myofibril assembly GO:0030239 154 0.013
axonogenesis GO:0007409 102 0.013
regulation of cell proliferation GO:0042127 105 0.013
Human Mouse Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.013
Human Fly
gene silencing by rna GO:0031047 143 0.013
aromatic compound catabolic process GO:0019439 116 0.013
protein complex assembly GO:0006461 186 0.013
cellular protein complex assembly GO:0043623 178 0.013
adult locomotory behavior GO:0008344 1 0.013
small gtpase mediated signal transduction GO:0007264 32 0.013
Worm
regulation of feeding behavior GO:0060259 38 0.013
negative regulation of transcription dna templated GO:0045892 53 0.013
Human Fly
positive regulation of striated muscle contraction GO:0045989 2 0.013
protein complex biogenesis GO:0070271 186 0.013
nucleobase containing compound catabolic process GO:0034655 114 0.012
response to wounding GO:0009611 4 0.012
regulation of cell migration GO:0030334 55 0.012
ras protein signal transduction GO:0007265 31 0.012
Worm
gene silencing GO:0016458 143 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
regulation of meiotic cell cycle GO:0051445 136 0.012
cell division GO:0051301 262 0.012
organelle fission GO:0048285 363 0.012
negative regulation of biosynthetic process GO:0009890 65 0.012
Human Fly
meiotic chromosome segregation GO:0045132 139 0.012
regulation of cellular component movement GO:0051270 62 0.012
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.012
Fly
cell surface receptor signaling pathway GO:0007166 149 0.012
nitrogen compound transport GO:0071705 49 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.012
Human Fly
pharyngeal pumping GO:0043050 58 0.012
response to bacterium GO:0009617 86 0.012
macromolecular complex assembly GO:0065003 193 0.011
inductive cell migration GO:0040039 145 0.011
gamete generation GO:0007276 461 0.011
Worm Fly
actomyosin structure organization GO:0031032 154 0.011
sexual reproduction GO:0019953 546 0.011
Worm Fly
cellular response to chemical stimulus GO:0070887 129 0.011
positive regulation of cellular biosynthetic process GO:0031328 109 0.011
Human Mouse Fly
heterocycle catabolic process GO:0046700 119 0.011
carbohydrate derivative metabolic process GO:1901135 141 0.011
myosin filament organization GO:0031033 138 0.011
meiotic cell cycle GO:0051321 335 0.011
response to abiotic stimulus GO:0009628 152 0.011
feeding behavior GO:0007631 70 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.011
dendrite development GO:0016358 42 0.011
Fly
cellular macromolecular complex assembly GO:0034622 184 0.011
cellular response to organic substance GO:0071310 119 0.011
cellular response to abiotic stimulus GO:0071214 4 0.011
epithelial cell proliferation GO:0050673 1 0.011
regulation of epithelial cell proliferation GO:0050678 1 0.011
rna biosynthetic process GO:0032774 169 0.011
Human Mouse Fly
protein oligomerization GO:0051259 4 0.011
posttranscriptional gene silencing GO:0016441 143 0.011
negative regulation of rna biosynthetic process GO:1902679 53 0.011
Human Fly
regulation of cell motility GO:2000145 57 0.011
meiotic nuclear division GO:0007126 300 0.010
negative regulation of nucleic acid templated transcription GO:1903507 53 0.010
Human Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.010
Human Fly
cellular nitrogen compound catabolic process GO:0044270 119 0.010
sensory organ morphogenesis GO:0090596 2 0.010
positive regulation of cell death GO:0010942 38 0.010
Fly
defense response to bacterium GO:0042742 86 0.010
myosin filament assembly GO:0031034 138 0.010

efl-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012