Caenorhabditis elegans

29 known processes

nhr-2 (CELE_C32F10.6)

Protein NHR-2

nhr-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.991
regulation of nucleic acid templated transcription GO:1903506 165 0.925
embryo development ending in birth or egg hatching GO:0009792 2992 0.920
rna metabolic process GO:0016070 228 0.899
heterocycle biosynthetic process GO:0018130 187 0.889
organic cyclic compound biosynthetic process GO:1901362 195 0.887
regulation of transcription dna templated GO:0006355 164 0.861
post embryonic development GO:0009791 2152 0.859
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.849
regulation of multicellular organismal process GO:0051239 726 0.843
cell fate commitment GO:0045165 139 0.843
regulation of rna metabolic process GO:0051252 173 0.841
gene expression GO:0010467 412 0.815
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.786
regulation of developmental process GO:0050793 684 0.776
regulation of nitrogen compound metabolic process GO:0051171 222 0.775
rna biosynthetic process GO:0032774 169 0.761
aromatic compound biosynthetic process GO:0019438 192 0.739
organic substance biosynthetic process GO:1901576 323 0.729
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.729
apoptotic process GO:0006915 478 0.714
locomotion GO:0040011 1634 0.700
regulation of primary metabolic process GO:0080090 292 0.678
transcription from rna polymerase ii promoter GO:0006366 149 0.670
transcription dna templated GO:0006351 168 0.654
regulation of macromolecule metabolic process GO:0060255 421 0.654
establishment of localization GO:0051234 1171 0.647
neuroblast fate determination GO:0007400 1 0.636
neuron projection guidance GO:0097485 82 0.636
developmental growth GO:0048589 412 0.632
regulation of cellular biosynthetic process GO:0031326 189 0.630
mesodermal cell differentiation GO:0048333 15 0.624
cellular nitrogen compound biosynthetic process GO:0044271 192 0.618
regulation of gene expression GO:0010468 366 0.613
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.610
regulation of rna biosynthetic process GO:2001141 165 0.594
nucleobase containing compound metabolic process GO:0006139 406 0.594
negative regulation of gene expression GO:0010629 217 0.585
transport GO:0006810 1093 0.582
nucleic acid templated transcription GO:0097659 169 0.576
macromolecular complex subunit organization GO:0043933 320 0.568
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.557
positive regulation of rna metabolic process GO:0051254 103 0.543
vesicle mediated transport GO:0016192 852 0.541
growth GO:0040007 562 0.526
cell death GO:0008219 547 0.519
positive regulation of multicellular organismal process GO:0051240 417 0.498
positive regulation of nucleic acid templated transcription GO:1903508 102 0.493
positive regulation of rna biosynthetic process GO:1902680 102 0.490
regulation of metabolic process GO:0019222 478 0.474
regulation of biosynthetic process GO:0009889 189 0.472
nucleic acid metabolic process GO:0090304 299 0.469
genitalia development GO:0048806 741 0.464
positive regulation of transcription dna templated GO:0045893 102 0.450
cellular biosynthetic process GO:0044249 315 0.447
regulation of cell division GO:0051302 142 0.439
regulation of meiosis GO:0040020 94 0.435
death GO:0016265 547 0.432
multicellular organismal reproductive behavior GO:0033057 384 0.432
biosynthetic process GO:0009058 323 0.430
multicellular organism reproduction GO:0032504 819 0.425
tissue development GO:0009888 112 0.408
regulation of nematode larval development GO:0061062 260 0.408
multi organism reproductive process GO:0044703 867 0.405
negative regulation of post embryonic development GO:0048581 208 0.403
multicellular organism growth GO:0035264 385 0.400
negative regulation of macromolecule metabolic process GO:0010605 229 0.396
behavior GO:0007610 527 0.396
regulation of cellular metabolic process GO:0031323 305 0.394
positive regulation of cellular process GO:0048522 332 0.391
axon guidance GO:0007411 82 0.390
regulation of meiotic cell cycle GO:0051445 136 0.389
secretion GO:0046903 147 0.385
nervous system development GO:0007399 253 0.384
taxis GO:0042330 128 0.380
multicellular organismal reproductive process GO:0048609 815 0.375
regulation of macromolecule biosynthetic process GO:0010556 189 0.372
nucleobase containing compound biosynthetic process GO:0034654 184 0.367
regulation of transcription from rna polymerase ii promoter in response to osmotic stress GO:0061392 1 0.366
negative regulation of vulval development GO:0040027 206 0.363
programmed cell death GO:0012501 500 0.360
neurogenesis GO:0022008 236 0.357
endocytosis GO:0006897 819 0.357
receptor mediated endocytosis GO:0006898 715 0.356
negative regulation of cellular biosynthetic process GO:0031327 65 0.352
positive regulation of multicellular organism growth GO:0040018 352 0.349
negative regulation of transcription dna templated GO:0045892 53 0.346
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.343
development of primary sexual characteristics GO:0045137 840 0.340
single organism reproductive process GO:0044702 1196 0.339
organ development GO:0048513 1102 0.331
cell development GO:0048468 696 0.329
regulation of developmental growth GO:0048638 389 0.320
negative regulation of rna biosynthetic process GO:1902679 53 0.304
positive regulation of growth GO:0045927 369 0.291
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.284
cellular macromolecule biosynthetic process GO:0034645 247 0.282
aging GO:0007568 812 0.273
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.272
regulation of post embryonic development GO:0048580 260 0.268
regulation of biological quality GO:0065008 741 0.267
negative regulation of biosynthetic process GO:0009890 65 0.265
meiotic cell cycle GO:0051321 335 0.265
developmental process involved in reproduction GO:0003006 1165 0.263
reproductive structure development GO:0048608 850 0.262
cellular component morphogenesis GO:0032989 318 0.257
neuroblast fate specification GO:0014018 4 0.257
vulval development GO:0040025 333 0.249
regulation of multicellular organismal development GO:2000026 317 0.246
regulation of cell differentiation GO:0045595 81 0.241
hermaphrodite genitalia development GO:0040035 734 0.241
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.239
negative regulation of nematode larval development GO:0061064 208 0.239
cell migration GO:0016477 306 0.237
calcium mediated signaling GO:0019722 3 0.236
regulation of neuron differentiation GO:0045664 40 0.235
regulation of vulval development GO:0040028 248 0.234
post embryonic organ development GO:0048569 336 0.234
gonad development GO:0008406 840 0.234
positive regulation of macromolecule metabolic process GO:0010604 149 0.233
reproductive system development GO:0061458 850 0.230
cell proliferation GO:0008283 116 0.230
regulation of growth GO:0040008 409 0.229
axon development GO:0061564 163 0.228
body morphogenesis GO:0010171 620 0.226
anatomical structure formation involved in morphogenesis GO:0048646 250 0.224
single organism localization GO:1902578 518 0.224
secretion by cell GO:0032940 138 0.214
cell cycle process GO:0022402 482 0.214
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.212
cell motility GO:0048870 313 0.212
mesoderm morphogenesis GO:0048332 24 0.207
positive regulation of developmental growth GO:0048639 354 0.206
regulation of multicellular organism growth GO:0040014 373 0.205
oviposition GO:0018991 364 0.205
neuron projection development GO:0031175 187 0.197
generation of neurons GO:0048699 235 0.193
cell projection organization GO:0030030 231 0.188
system process GO:0003008 136 0.187
regulation of locomotion GO:0040012 161 0.186
neuron differentiation GO:0030182 217 0.186
regulation of cell development GO:0060284 49 0.185
digestive system development GO:0055123 122 0.179
positive regulation of metabolic process GO:0009893 187 0.178
negative regulation of developmental process GO:0051093 227 0.177
neuron development GO:0048666 199 0.177
negative regulation of metabolic process GO:0009892 240 0.175
negative regulation of nucleic acid templated transcription GO:1903507 53 0.167
gamete generation GO:0007276 461 0.166
multi organism reproductive behavior GO:0044705 387 0.165
striated muscle cell development GO:0055002 157 0.161
sexual reproduction GO:0019953 546 0.160
chemotaxis GO:0006935 120 0.155
single organism transport GO:0044765 447 0.154
establishment of localization in cell GO:0051649 318 0.152
positive regulation of developmental process GO:0051094 408 0.151
positive regulation of transcription from rna polymerase ii promoter in response to increased salt GO:0061404 1 0.148
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.146
mesodermal cell fate specification GO:0007501 13 0.146
negative regulation of cellular process GO:0048523 239 0.145
macromolecule localization GO:0033036 771 0.144
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.139
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.138
neuron recognition GO:0008038 83 0.136
negative regulation of cellular metabolic process GO:0031324 95 0.136
sensory organ morphogenesis GO:0090596 2 0.136
protein complex subunit organization GO:0071822 280 0.135
multi multicellular organism process GO:0044706 390 0.135
macromolecular complex assembly GO:0065003 193 0.133
reproductive behavior GO:0019098 387 0.132
multi organism behavior GO:0051705 389 0.128
organelle organization GO:0006996 783 0.126
regulation of nuclear division GO:0051783 115 0.125
negative regulation of biological process GO:0048519 567 0.121
regulation of neurogenesis GO:0050767 40 0.119
protein localization GO:0008104 205 0.119
regulation of cell cycle process GO:0010564 145 0.118
negative regulation of multicellular organismal process GO:0051241 236 0.117
macromolecule biosynthetic process GO:0009059 250 0.115
myofibril assembly GO:0030239 154 0.114
cellular localization GO:0051641 360 0.113
axonogenesis GO:0007409 102 0.106
organelle localization GO:0051640 127 0.106
cell division GO:0051301 262 0.104
protein metabolic process GO:0019538 422 0.103
membrane organization GO:0061024 135 0.100
membrane fusion GO:0061025 16 0.100
positive regulation of cellular metabolic process GO:0031325 178 0.099
multicellular organismal aging GO:0010259 812 0.098
positive regulation of cellular biosynthetic process GO:0031328 109 0.098
muscle cell development GO:0055001 158 0.097
positive regulation of biosynthetic process GO:0009891 109 0.097
embryonic morphogenesis GO:0048598 152 0.093
determination of adult lifespan GO:0008340 812 0.093
response to wounding GO:0009611 4 0.092
maintenance of location GO:0051235 580 0.092
striated muscle myosin thick filament assembly GO:0071688 138 0.084
chromosome segregation GO:0007059 180 0.083
sex differentiation GO:0007548 909 0.083
cellular component movement GO:0006928 388 0.081
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.081
organelle assembly GO:0070925 214 0.079
epithelial cell proliferation GO:0050673 1 0.079
lipid localization GO:0010876 573 0.079
oocyte development GO:0048599 44 0.078
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 2 0.077
germ cell development GO:0007281 351 0.077
positive regulation of transcription from rna polymerase ii promoter involved in defense response to fungus GO:1901244 1 0.076
lipid storage GO:0019915 565 0.076
neuroblast fate commitment GO:0014017 5 0.074
asymmetric cell division GO:0008356 36 0.074
tube development GO:0035295 126 0.074
cellular component assembly involved in morphogenesis GO:0010927 183 0.073
cell cycle GO:0007049 526 0.071
mitotic cell cycle process GO:1903047 194 0.071
positive regulation of epithelial cell proliferation GO:0050679 1 0.070
meiotic nuclear division GO:0007126 300 0.068
meiotic cell cycle process GO:1903046 170 0.066
actin cytoskeleton organization GO:0030036 184 0.066
regulation of cell proliferation GO:0042127 105 0.064
neuron fate specification GO:0048665 8 0.063
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 2 0.063
cellular macromolecular complex assembly GO:0034622 184 0.062
covalent chromatin modification GO:0016569 30 0.061
chromatin modification GO:0016568 32 0.061
cell type specific apoptotic process GO:0097285 4 0.061
inductive cell migration GO:0040039 145 0.059
protein modification process GO:0036211 207 0.059
regulation of mitotic cell cycle GO:0007346 76 0.055
striated muscle cell differentiation GO:0051146 158 0.054
regulation of cellular component organization GO:0051128 248 0.053
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.052
positive regulation of transcription from rna polymerase ii promoter in response to osmotic stress GO:0061393 1 0.052
positive regulation of apoptotic process GO:0043065 17 0.052
response to external stimulus GO:0009605 289 0.052
regulation of programmed cell death GO:0043067 50 0.051
chromatin organization GO:0006325 32 0.051
intracellular signal transduction GO:0035556 96 0.051
protein complex assembly GO:0006461 186 0.050
endodermal cell fate determination GO:0007493 2 0.049
cellular macromolecule localization GO:0070727 75 0.049
axonal fasciculation GO:0007413 79 0.049
cell recognition GO:0008037 85 0.047
cellular hyperosmotic salinity response GO:0071475 1 0.047
negative regulation of bmp signaling pathway GO:0030514 1 0.046
mesoderm development GO:0007498 27 0.045
phosphorylation GO:0016310 116 0.044
axon extension involved in axon guidance GO:0048846 13 0.044
regulation of localization GO:0032879 194 0.044
cellular response to abiotic stimulus GO:0071214 4 0.044
muscle cell differentiation GO:0042692 171 0.043
cell part morphogenesis GO:0032990 152 0.042
protein complex biogenesis GO:0070271 186 0.042
cellular protein complex assembly GO:0043623 178 0.042
regulation of epithelial cell proliferation GO:0050678 1 0.042
gastrulation GO:0007369 58 0.042
organic substance transport GO:0071702 113 0.041
neuron projection extension GO:1990138 37 0.041
cellular protein metabolic process GO:0044267 279 0.041
organelle fission GO:0048285 363 0.040
proximal distal pattern formation GO:0009954 6 0.040
negative regulation of rna metabolic process GO:0051253 53 0.040
female gamete generation GO:0007292 254 0.039
single organism organelle organization GO:1902589 501 0.039
negative regulation of neurogenesis GO:0050768 4 0.039
epithelial tube morphogenesis GO:0060562 1 0.038
actomyosin structure organization GO:0031032 154 0.038
muscle tissue development GO:0060537 1 0.036
histone modification GO:0016570 30 0.036
epithelial cell differentiation GO:0030855 17 0.036
regulation of reproductive process GO:2000241 66 0.036
regulation of epithelial cell differentiation GO:0030856 4 0.036
positive regulation of gene expression GO:0010628 112 0.035
small molecule metabolic process GO:0044281 186 0.035
meiotic chromosome segregation GO:0045132 139 0.035
regulation of development heterochronic GO:0040034 18 0.035
cellular component biogenesis GO:0044085 297 0.034
neuron projection morphogenesis GO:0048812 114 0.034
response to abiotic stimulus GO:0009628 152 0.034
posttranscriptional regulation of gene expression GO:0010608 166 0.033
nematode male tail tip morphogenesis GO:0045138 77 0.032
epithelium development GO:0060429 68 0.031
intracellular transport GO:0046907 77 0.031
regulation of transcription from rna polymerase ii promoter in response to salt stress GO:0061416 1 0.031
digestive tract morphogenesis GO:0048546 76 0.030
negative regulation of signaling GO:0023057 61 0.030
epidermal cell fate specification GO:0009957 5 0.030
regulation of gene expression epigenetic GO:0040029 163 0.030
regulation of response to stimulus GO:0048583 243 0.030
positive regulation of embryonic development GO:0040019 3 0.028
cytoskeleton organization GO:0007010 339 0.028
cellular component assembly GO:0022607 293 0.028
response to chemical GO:0042221 356 0.028
organ morphogenesis GO:0009887 67 0.028
homeostatic process GO:0042592 51 0.027
cell projection morphogenesis GO:0048858 148 0.027
regulation of apoptotic process GO:0042981 36 0.027
cell cell signaling GO:0007267 118 0.026
muscle structure development GO:0061061 191 0.026
negative regulation of response to stimulus GO:0048585 73 0.025
macromolecule modification GO:0043412 218 0.025
sex determination GO:0007530 60 0.025
phosphorus metabolic process GO:0006793 232 0.025
regulation of cell cycle GO:0051726 194 0.024
cellular protein modification process GO:0006464 207 0.024
regulation of cytoplasmic transport GO:1903649 3 0.023
positive regulation of transcription from rna polymerase ii promoter in response to salt stress GO:0036251 1 0.023
regulation of cell communication GO:0010646 176 0.023
regulation of organelle organization GO:0033043 164 0.023
oogenesis GO:0048477 229 0.023
neurological system process GO:0050877 53 0.023
gene silencing GO:0016458 143 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.022
myosin filament organization GO:0031033 138 0.022
pharynx development GO:0060465 51 0.022
regulation of signaling GO:0023051 172 0.022
actin filament based process GO:0030029 191 0.021
dosage compensation by hypoactivation of x chromosome GO:0042464 11 0.021
regulation of cell migration GO:0030334 55 0.021
regulation of phosphate metabolic process GO:0019220 81 0.020
negative regulation of signal transduction GO:0009968 60 0.020
single organism membrane organization GO:0044802 35 0.020
positive regulation of cell death GO:0010942 38 0.020
excretion GO:0007588 49 0.019
spermatogenesis GO:0007283 41 0.019
microtubule based process GO:0007017 182 0.019
regulation of system process GO:0044057 27 0.019
myosin filament assembly GO:0031034 138 0.018
head development GO:0060322 1 0.018
anterior posterior pattern specification GO:0009952 27 0.018
regulation of intracellular signal transduction GO:1902531 77 0.018
immune response GO:0006955 192 0.017
digestive tract development GO:0048565 122 0.017
regulation of embryonic development GO:0045995 16 0.017
ectoderm development GO:0007398 3 0.017
response to metal ion GO:0010038 33 0.017
dauer larval development GO:0040024 92 0.016
embryonic body morphogenesis GO:0010172 49 0.016
negative regulation of cell communication GO:0010648 61 0.016
rna interference GO:0016246 137 0.016
positive regulation of programmed cell death GO:0043068 27 0.016
negative regulation of cell cycle g2 m phase transition GO:1902750 1 0.016
response to inorganic substance GO:0010035 50 0.015
regulation of molecular function GO:0065009 89 0.015
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.015
nucleus localization GO:0051647 55 0.015
pronuclear migration GO:0035046 51 0.015
development of primary male sexual characteristics GO:0046546 4 0.015
cell morphogenesis involved in differentiation GO:0000904 112 0.014
pattern specification process GO:0007389 59 0.014
cellular protein localization GO:0034613 75 0.014
regulation of multi organism process GO:0043900 69 0.014
defecation GO:0030421 47 0.014
organonitrogen compound biosynthetic process GO:1901566 44 0.014
male sex differentiation GO:0046661 86 0.014
phagocytosis engulfment GO:0006911 98 0.014
signaling GO:0023052 401 0.014
eating behavior GO:0042755 59 0.014
cell growth GO:0016049 44 0.013
canonical wnt signaling pathway GO:0060070 3 0.013
cellular ketone metabolic process GO:0042180 14 0.013
regulation of cell death GO:0010941 65 0.013
defecation rhythm GO:0035882 3 0.013
regulation of oviposition GO:0046662 43 0.013
muscle fiber development GO:0048747 2 0.013
male anatomical structure morphogenesis GO:0090598 78 0.013
positive regulation of neuron differentiation GO:0045666 4 0.013
response to extracellular stimulus GO:0009991 38 0.013
endomembrane system organization GO:0010256 22 0.012
defense response GO:0006952 296 0.012
regulation of behavior GO:0050795 97 0.012
skeletal muscle organ development GO:0060538 3 0.012
organic substance catabolic process GO:1901575 294 0.012
chemosensory behavior GO:0007635 33 0.011
feeding behavior GO:0007631 70 0.011
axon extension GO:0048675 37 0.011
localization of cell GO:0051674 313 0.011
male gonad development GO:0008584 4 0.011
catabolic process GO:0009056 318 0.011
regulation of cellular component movement GO:0051270 62 0.011
regulation of cell fate specification GO:0042659 22 0.011
protein oligomerization GO:0051259 4 0.011
response to drug GO:0042493 14 0.011
negative regulation of apoptotic process GO:0043066 17 0.011
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.011
regulation of dna templated transcription in response to stress GO:0043620 3 0.011
phagocytosis GO:0006909 115 0.011
muscle system process GO:0003012 43 0.010
bmp signaling pathway GO:0030509 3 0.010
regulation of transport GO:0051049 91 0.010
regulation of nervous system development GO:0051960 41 0.010
posttranscriptional gene silencing by rna GO:0035194 143 0.010
cellular response to nutrient levels GO:0031669 13 0.010
positive regulation of cell communication GO:0010647 69 0.010

nhr-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.016
large intestine cancer DOID:5672 0 0.014
gastrointestinal system cancer DOID:3119 0 0.014
intestinal cancer DOID:10155 0 0.014
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
disease of anatomical entity DOID:7 0 0.011