Caenorhabditis elegans

84 known processes

lin-35 (CELE_C32F10.2)

Protein LIN-35

lin-35 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of rna biosynthetic process GO:2001141 165 0.995
Human Mouse Fly
single organism reproductive process GO:0044702 1196 0.994
regulation of cellular biosynthetic process GO:0031326 189 0.990
Human Mouse Fly
regulation of biosynthetic process GO:0009889 189 0.988
Human Mouse Fly
regulation of transcription dna templated GO:0006355 164 0.981
Human Mouse Fly
rna metabolic process GO:0016070 228 0.976
Human Mouse Fly
transcription dna templated GO:0006351 168 0.968
Human Mouse Fly
hermaphrodite genitalia development GO:0040035 734 0.963
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.957
Mouse
genitalia development GO:0048806 741 0.956
gene expression GO:0010467 412 0.954
Human Mouse Fly
regulation of nucleic acid templated transcription GO:1903506 165 0.953
Human Mouse Fly
sex differentiation GO:0007548 909 0.950
reproductive system development GO:0061458 850 0.941
nucleic acid templated transcription GO:0097659 169 0.936
Human Mouse Fly
regulation of gene expression GO:0010468 366 0.935
Human Mouse Fly
regulation of macromolecule biosynthetic process GO:0010556 189 0.921
Human Mouse Fly
gonad development GO:0008406 840 0.910
reproductive structure development GO:0048608 850 0.910
oviposition GO:0018991 364 0.904
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.876
Mouse Fly
positive regulation of transcription dna templated GO:0045893 102 0.871
Mouse
regulation of rna metabolic process GO:0051252 173 0.863
Human Mouse Fly
aromatic compound biosynthetic process GO:0019438 192 0.826
Human Mouse Fly
cellular macromolecule biosynthetic process GO:0034645 247 0.811
Human Mouse Fly
regulation of vulval development GO:0040028 248 0.802
regulation of macromolecule metabolic process GO:0060255 421 0.801
Human Mouse Fly
organic cyclic compound biosynthetic process GO:1901362 195 0.780
Human Mouse Fly
regulation of nitrogen compound metabolic process GO:0051171 222 0.775
Human Mouse Fly
positive regulation of rna biosynthetic process GO:1902680 102 0.742
Mouse
development of primary sexual characteristics GO:0045137 840 0.739
cellular nitrogen compound biosynthetic process GO:0044271 192 0.718
Human Mouse Fly
transcription from rna polymerase ii promoter GO:0006366 149 0.717
Mouse Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.711
Human Mouse Fly
heterocycle biosynthetic process GO:0018130 187 0.667
Human Mouse Fly
multicellular organism reproduction GO:0032504 819 0.666
negative regulation of nematode larval development GO:0061064 208 0.637
programmed cell death GO:0012501 500 0.580
rna biosynthetic process GO:0032774 169 0.572
Human Mouse Fly
developmental process involved in reproduction GO:0003006 1165 0.571
multi organism reproductive process GO:0044703 867 0.507
single fertilization GO:0007338 61 0.500
multicellular organismal reproductive process GO:0048609 815 0.493
regulation of metabolic process GO:0019222 478 0.492
Human Mouse Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.489
Mouse
sexual reproduction GO:0019953 546 0.484
positive regulation of nucleic acid templated transcription GO:1903508 102 0.481
Mouse
fertilization GO:0009566 63 0.442
negative regulation of vulval development GO:0040027 206 0.424
nucleobase containing compound metabolic process GO:0006139 406 0.412
Human Mouse Fly
organ development GO:0048513 1102 0.399
multi organism behavior GO:0051705 389 0.388
positive regulation of rna metabolic process GO:0051254 103 0.376
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.369
Mouse
multi organism reproductive behavior GO:0044705 387 0.356
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.345
negative regulation of macromolecule metabolic process GO:0010605 229 0.341
Human Mouse Fly
meiotic cell cycle GO:0051321 335 0.333
pronuclear migration GO:0035046 51 0.327
body morphogenesis GO:0010171 620 0.324
vulval development GO:0040025 333 0.322
macromolecule biosynthetic process GO:0009059 250 0.309
Human Mouse Fly
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.301
Human Mouse Fly
regulation of developmental growth GO:0048638 389 0.294
chromatin modification GO:0016568 32 0.294
posttranscriptional regulation of gene expression GO:0010608 166 0.293
death GO:0016265 547 0.281
chromosome organization GO:0051276 104 0.281
Human Fly
negative regulation of biosynthetic process GO:0009890 65 0.278
Human Mouse Fly
reproductive behavior GO:0019098 387 0.275
post embryonic organ development GO:0048569 336 0.274
nucleobase containing compound biosynthetic process GO:0034654 184 0.269
Human Mouse Fly
nucleic acid metabolic process GO:0090304 299 0.269
Human Mouse Fly
negative regulation of gene expression GO:0010629 217 0.268
Human Mouse Fly
positive regulation of cellular biosynthetic process GO:0031328 109 0.268
Mouse
chromatin organization GO:0006325 32 0.263
positive regulation of gene expression GO:0010628 112 0.260
Mouse
multicellular organismal aging GO:0010259 812 0.257
germ cell development GO:0007281 351 0.252
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.238
Human Mouse Fly
meiotic nuclear division GO:0007126 300 0.233
multi multicellular organism process GO:0044706 390 0.232
multicellular organismal reproductive behavior GO:0033057 384 0.232
negative regulation of cellular process GO:0048523 239 0.224
positive regulation of biosynthetic process GO:0009891 109 0.211
Mouse
cell motility GO:0048870 313 0.197
biosynthetic process GO:0009058 323 0.187
Human Mouse Fly
negative regulation of developmental process GO:0051093 227 0.186
cellular response to stress GO:0033554 162 0.184
Fly
oogenesis GO:0048477 229 0.181
regulation of gene expression epigenetic GO:0040029 163 0.169
cellular component assembly GO:0022607 293 0.168
positive regulation of cellular process GO:0048522 332 0.166
Human Mouse
gamete generation GO:0007276 461 0.162
negative regulation of cellular biosynthetic process GO:0031327 65 0.143
Human Mouse Fly
determination of adult lifespan GO:0008340 812 0.137
dendrite development GO:0016358 42 0.135
regulation of developmental process GO:0050793 684 0.133
posttranscriptional gene silencing GO:0016441 143 0.130
regulation of meiotic cell cycle GO:0051445 136 0.120
behavior GO:0007610 527 0.118
regulation of cellular metabolic process GO:0031323 305 0.111
Human Mouse Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.105
Human Mouse Fly
positive regulation of developmental process GO:0051094 408 0.102
cellular protein metabolic process GO:0044267 279 0.101
Human
growth GO:0040007 562 0.097
positive regulation of vulval development GO:0040026 52 0.097
gene silencing GO:0016458 143 0.093
embryo development GO:0009790 3052 0.091
chromatin remodeling GO:0006338 2 0.091
localization of cell GO:0051674 313 0.088
positive regulation of nematode larval development GO:0061063 54 0.085
epidermis development GO:0008544 24 0.083
regulation of organelle organization GO:0033043 164 0.081
Human Fly
establishment of nucleus localization GO:0040023 55 0.080
regulation of meiosis GO:0040020 94 0.079
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.078
Human Mouse Fly
posttranscriptional gene silencing by rna GO:0035194 143 0.077
female gamete generation GO:0007292 254 0.076
chromosome segregation GO:0007059 180 0.076
Human Fly
regulation of multicellular organismal development GO:2000026 317 0.076
aging GO:0007568 812 0.076
gene silencing by rna GO:0031047 143 0.074
receptor mediated endocytosis GO:0006898 715 0.074
embryo development ending in birth or egg hatching GO:0009792 2992 0.073
negative regulation of biological process GO:0048519 567 0.072
organelle organization GO:0006996 783 0.072
Human Fly
regulation of nematode larval development GO:0061062 260 0.072
nuclear migration GO:0007097 54 0.072
catabolic process GO:0009056 318 0.071
Human
regulation of primary metabolic process GO:0080090 292 0.071
Human Mouse Fly
positive regulation of multicellular organism growth GO:0040018 352 0.070
negative regulation of post embryonic development GO:0048581 208 0.068
positive regulation of intracellular transport GO:0032388 2 0.065
protein catabolic process GO:0030163 162 0.062
Human
negative regulation of rna biosynthetic process GO:1902679 53 0.061
Human Mouse Fly
regulation of multicellular organismal process GO:0051239 726 0.060
negative regulation of cellular metabolic process GO:0031324 95 0.059
Human Mouse Fly
rna interference GO:0016246 137 0.059
internal peptidyl lysine acetylation GO:0018393 3 0.056
cell death GO:0008219 547 0.054
response to biotic stimulus GO:0009607 101 0.054
macromolecular complex assembly GO:0065003 193 0.053
spermatogenesis GO:0007283 41 0.051
negative regulation of transcription dna templated GO:0045892 53 0.050
Human Mouse Fly
symbiosis encompassing mutualism through parasitism GO:0044403 5 0.050
macromolecular complex subunit organization GO:0043933 320 0.049
negative regulation of rna metabolic process GO:0051253 53 0.048
Human Mouse Fly
rna processing GO:0006396 34 0.048
head development GO:0060322 1 0.047
developmental growth GO:0048589 412 0.046
lipid storage GO:0019915 565 0.045
positive regulation of neurogenesis GO:0050769 4 0.044
maintenance of location GO:0051235 580 0.044
Human
covalent chromatin modification GO:0016569 30 0.044
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.044
Mouse Fly
cellular component assembly involved in morphogenesis GO:0010927 183 0.043
response to external stimulus GO:0009605 289 0.043
regeneration GO:0031099 4 0.041
dna metabolic process GO:0006259 74 0.041
Fly
chromatin assembly or disassembly GO:0006333 1 0.040
nucleus localization GO:0051647 55 0.040
regulation of biological quality GO:0065008 741 0.040
Human Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.039
Mouse
response to other organism GO:0051707 101 0.039
regulation of multi organism process GO:0043900 69 0.038
mrna metabolic process GO:0016071 31 0.038
regulation of apoptotic signaling pathway GO:2001233 1 0.038
regulation of locomotion GO:0040012 161 0.037
positive regulation of signal transduction GO:0009967 40 0.037
organic substance catabolic process GO:1901575 294 0.036
Human
cellular component biogenesis GO:0044085 297 0.035
male gamete generation GO:0048232 41 0.035
multicellular organism growth GO:0035264 385 0.035
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.035
Human Mouse Fly
negative regulation of metabolic process GO:0009892 240 0.034
Human Mouse Fly
positive regulation of growth GO:0045927 369 0.034
protein complex subunit organization GO:0071822 280 0.034
protein polymerization GO:0051258 26 0.033
defense response GO:0006952 296 0.033
intracellular receptor signaling pathway GO:0030522 2 0.033
regulation of programmed cell death GO:0043067 50 0.032
Fly
regulation of cytoplasmic transport GO:1903649 3 0.032
muscle tissue development GO:0060537 1 0.031
Mouse
cell migration GO:0016477 306 0.031
digestive tract development GO:0048565 122 0.031
regulation of growth GO:0040008 409 0.031
cellular macromolecular complex assembly GO:0034622 184 0.029
positive regulation of developmental growth GO:0048639 354 0.029
dna conformation change GO:0071103 11 0.029
inductive cell migration GO:0040039 145 0.027
positive regulation of response to stimulus GO:0048584 55 0.027
regulation of apoptotic process GO:0042981 36 0.027
Fly
molting cycle GO:0042303 281 0.024
transport GO:0006810 1093 0.023
negative regulation of nucleic acid templated transcription GO:1903507 53 0.023
Human Mouse Fly
positive regulation of cell communication GO:0010647 69 0.023
cell growth GO:0016049 44 0.023
cellular component movement GO:0006928 388 0.023
regulation of nucleocytoplasmic transport GO:0046822 3 0.023
locomotion GO:0040011 1634 0.023
regulation of protein import into nucleus GO:0042306 3 0.023
protein modification process GO:0036211 207 0.022
Human
lipid localization GO:0010876 573 0.022
ribosome biogenesis GO:0042254 4 0.021
striated muscle cell differentiation GO:0051146 158 0.021
Mouse
response to wounding GO:0009611 4 0.020
regulation of multicellular organism growth GO:0040014 373 0.020
cell cycle GO:0007049 526 0.019
cytoskeleton organization GO:0007010 339 0.019
Human
cell part morphogenesis GO:0032990 152 0.019
macromolecule catabolic process GO:0009057 202 0.019
Human
chromatin assembly GO:0031497 1 0.019
negative regulation of neurogenesis GO:0050768 4 0.019
meiotic cell cycle process GO:1903046 170 0.018
protein dna complex assembly GO:0065004 7 0.018
cell cycle process GO:0022402 482 0.018
response to external biotic stimulus GO:0043207 101 0.018
microtubule polymerization or depolymerization GO:0031109 22 0.017
positive regulation of multicellular organismal process GO:0051240 417 0.017
alternative mrna splicing via spliceosome GO:0000380 7 0.017
meiotic chromosome segregation GO:0045132 139 0.017
regulation of cell cycle GO:0051726 194 0.017
heterocycle catabolic process GO:0046700 119 0.017
dauer larval development GO:0040024 92 0.016
rrna processing GO:0006364 3 0.016
response to abiotic stimulus GO:0009628 152 0.016
dna templated transcription elongation GO:0006354 1 0.016
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.016
phagocytosis GO:0006909 115 0.016
positive regulation of macromolecule metabolic process GO:0010604 149 0.016
Human Mouse
negative regulation of gene expression epigenetic GO:0045814 2 0.016
cell projection organization GO:0030030 231 0.015
Mouse
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
canonical wnt signaling pathway GO:0060070 3 0.015
regulation of chromatin modification GO:1903308 2 0.015
negative regulation of mitotic cell cycle GO:0045930 42 0.015
Mouse Fly
establishment of mitotic spindle orientation GO:0000132 28 0.015
dendrite morphogenesis GO:0048813 9 0.015
aromatic compound catabolic process GO:0019439 116 0.015
embryonic morphogenesis GO:0048598 152 0.014
dna packaging GO:0006323 7 0.014
cell surface receptor signaling pathway GO:0007166 149 0.014
Mouse
protein complex assembly GO:0006461 186 0.014
regulation of signaling GO:0023051 172 0.014
Mouse
regulation of cell proliferation GO:0042127 105 0.014
Mouse Fly
post embryonic development GO:0009791 2152 0.014
purine containing compound catabolic process GO:0072523 75 0.014
apoptotic process GO:0006915 478 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.013
g1 s transition of mitotic cell cycle GO:0000082 2 0.013
Mouse Fly
positive regulation of post embryonic development GO:0048582 54 0.013
endocytosis GO:0006897 819 0.013
positive regulation of cell cycle GO:0045787 55 0.013
Human
cell fate commitment GO:0045165 139 0.013
interspecies interaction between organisms GO:0044419 5 0.013
nucleus organization GO:0006997 38 0.013
organic substance biosynthetic process GO:1901576 323 0.013
Human Mouse Fly
regulation of mitotic cell cycle GO:0007346 76 0.013
Human Mouse Fly
modification of morphology or physiology of other organism GO:0035821 2 0.012
positive regulation of signaling GO:0023056 66 0.012
regulation of mitochondrion organization GO:0010821 1 0.012
axonal fasciculation GO:0007413 79 0.012
muscle structure development GO:0061061 191 0.012
Human Mouse
male anatomical structure morphogenesis GO:0090598 78 0.012
protein modification by small protein conjugation or removal GO:0070647 40 0.012
organelle fission GO:0048285 363 0.012
Human Fly
negative regulation of multicellular organismal process GO:0051241 236 0.012
glycosyl compound catabolic process GO:1901658 79 0.012
protein metabolic process GO:0019538 422 0.012
Human
negative regulation of apoptotic process GO:0043066 17 0.012
Fly
cellular nitrogen compound catabolic process GO:0044270 119 0.012
protein dna complex subunit organization GO:0071824 7 0.012
digestive system development GO:0055123 122 0.011
regulation of localization GO:0032879 194 0.011
Human Fly
striated muscle cell development GO:0055002 157 0.011
establishment of organelle localization GO:0051656 123 0.011
Human
regulation of cellular amine metabolic process GO:0033238 0 0.011
skeletal muscle organ development GO:0060538 3 0.011
Mouse
notch signaling pathway GO:0007219 22 0.011
regulation of cellular component movement GO:0051270 62 0.011
skin development GO:0043588 24 0.011
regulation of canonical wnt signaling pathway GO:0060828 1 0.010
protein complex biogenesis GO:0070271 186 0.010
tube development GO:0035295 126 0.010
cell cycle g1 s phase transition GO:0044843 2 0.010
Mouse Fly
muscle cell differentiation GO:0042692 171 0.010
Human Mouse
immune response GO:0006955 192 0.010

lin-35 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.023
Human
disease of cellular proliferation DOID:14566 0 0.023
Human