Caenorhabditis elegans

51 known processes

act-5 (CELE_T25C8.2)

Protein ACT-5

act-5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organ development GO:0048513 1102 0.817
single organism reproductive process GO:0044702 1196 0.626
gonad development GO:0008406 840 0.602
organelle fission GO:0048285 363 0.574
Worm
embryo development ending in birth or egg hatching GO:0009792 2992 0.569
post embryonic development GO:0009791 2152 0.558
meiotic nuclear division GO:0007126 300 0.523
Worm
microvillus organization GO:0032528 1 0.501
genitalia development GO:0048806 741 0.497
embryo development GO:0009790 3052 0.458
locomotion GO:0040011 1634 0.454
Worm
gamete generation GO:0007276 461 0.451
cell death GO:0008219 547 0.438
cell migration GO:0016477 306 0.393
Worm
development of primary sexual characteristics GO:0045137 840 0.391
developmental process involved in reproduction GO:0003006 1165 0.390
cellular component movement GO:0006928 388 0.388
Worm
molting cycle GO:0042303 281 0.350
death GO:0016265 547 0.346
receptor mediated endocytosis GO:0006898 715 0.334
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.334
transport GO:0006810 1093 0.331
signal transduction GO:0007165 317 0.327
localization of cell GO:0051674 313 0.310
Worm
establishment of localization GO:0051234 1171 0.310
programmed cell death GO:0012501 500 0.307
meiotic cell cycle GO:0051321 335 0.304
Yeast Worm
endocytosis GO:0006897 819 0.302
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.293
mitotic cell cycle process GO:1903047 194 0.277
Worm
vesicle mediated transport GO:0016192 852 0.276
reproductive system development GO:0061458 850 0.274
inductive cell migration GO:0040039 145 0.270
Worm
growth GO:0040007 562 0.270
Worm
sex differentiation GO:0007548 909 0.268
cell motility GO:0048870 313 0.268
Worm
multicellular organism reproduction GO:0032504 819 0.265
single organism organelle organization GO:1902589 501 0.264
Yeast Mouse Worm
cellular component assembly GO:0022607 293 0.226
sexual reproduction GO:0019953 546 0.214
Yeast
reproductive structure development GO:0048608 850 0.196
organelle organization GO:0006996 783 0.192
Human Yeast Mouse Worm
cellular component biogenesis GO:0044085 297 0.191
apoptotic process GO:0006915 478 0.183
signaling GO:0023052 401 0.182
regulation of multicellular organismal process GO:0051239 726 0.176
germ cell development GO:0007281 351 0.168
cell cycle process GO:0022402 482 0.165
Yeast Worm
positive regulation of developmental growth GO:0048639 354 0.161
multi organism reproductive process GO:0044703 867 0.160
Yeast
nervous system development GO:0007399 253 0.157
Human
macromolecule localization GO:0033036 771 0.157
Yeast
developmental growth GO:0048589 412 0.152
regulation of developmental growth GO:0048638 389 0.151
cell cycle GO:0007049 526 0.146
Yeast Worm
negative regulation of biological process GO:0048519 567 0.144
female gamete generation GO:0007292 254 0.141
positive regulation of multicellular organismal process GO:0051240 417 0.139
regulation of developmental process GO:0050793 684 0.134
positive regulation of multicellular organism growth GO:0040018 352 0.132
regulation of multicellular organism growth GO:0040014 373 0.126
muscle cell differentiation GO:0042692 171 0.119
Mouse Worm
cellular response to topologically incorrect protein GO:0035967 76 0.118
positive regulation of growth GO:0045927 369 0.117
microvillus assembly GO:0030033 1 0.115
ovulation GO:0030728 33 0.109
lipid localization GO:0010876 573 0.108
establishment of organelle localization GO:0051656 123 0.107
macromolecular complex subunit organization GO:0043933 320 0.106
Human Yeast Worm
tube formation GO:0035148 2 0.104
multicellular organismal reproductive process GO:0048609 815 0.103
protein complex subunit organization GO:0071822 280 0.102
Worm
multicellular organism growth GO:0035264 385 0.099
hermaphrodite genitalia development GO:0040035 734 0.099
cell development GO:0048468 696 0.098
Yeast Mouse Worm
positive regulation of cellular process GO:0048522 332 0.097
determination of adult lifespan GO:0008340 812 0.097
aging GO:0007568 812 0.093
Yeast
regulation of biological quality GO:0065008 741 0.093
Human
maintenance of location GO:0051235 580 0.093
gene expression GO:0010467 412 0.090
regulation of metabolic process GO:0019222 478 0.090
cellular response to chemical stimulus GO:0070887 129 0.090
Yeast
cellular protein complex assembly GO:0043623 178 0.090
Worm
response to chemical GO:0042221 356 0.089
Yeast
multicellular organismal aging GO:0010259 812 0.089
actin cytoskeleton organization GO:0030036 184 0.088
Mouse Worm
cell projection organization GO:0030030 231 0.087
lipid storage GO:0019915 565 0.084
cellular response to organic substance GO:0071310 119 0.082
response to topologically incorrect protein GO:0035966 82 0.081
striated muscle cell differentiation GO:0051146 158 0.079
Mouse Worm
reproductive behavior GO:0019098 387 0.076
tube development GO:0035295 126 0.075
single organism signaling GO:0044700 401 0.075
anatomical structure formation involved in morphogenesis GO:0048646 250 0.073
tube morphogenesis GO:0035239 79 0.070
organic substance biosynthetic process GO:1901576 323 0.069
oogenesis GO:0048477 229 0.067
nucleobase containing small molecule metabolic process GO:0055086 115 0.067
single organism localization GO:1902578 518 0.066
Yeast
positive regulation of developmental process GO:0051094 408 0.066
er nucleus signaling pathway GO:0006984 66 0.063
regulation of growth GO:0040008 409 0.063
response to endoplasmic reticulum stress GO:0034976 71 0.061
regulation of response to stimulus GO:0048583 243 0.060
cellular response to unfolded protein GO:0034620 71 0.060
cellular component assembly involved in morphogenesis GO:0010927 183 0.059
Yeast Mouse Worm
endoplasmic reticulum unfolded protein response GO:0030968 66 0.058
protein complex assembly GO:0006461 186 0.058
Worm
cytoskeleton organization GO:0007010 339 0.057
Mouse Worm
macromolecule biosynthetic process GO:0009059 250 0.057
biosynthetic process GO:0009058 323 0.057
striated muscle myosin thick filament assembly GO:0071688 138 0.055
Worm
organelle localization GO:0051640 127 0.054
system process GO:0003008 136 0.053
nuclear migration GO:0007097 54 0.052
small molecule biosynthetic process GO:0044283 38 0.052
membrane organization GO:0061024 135 0.051
macromolecular complex assembly GO:0065003 193 0.050
Worm
striated muscle cell development GO:0055002 157 0.050
Mouse Worm
protein complex biogenesis GO:0070271 186 0.049
Worm
regulation of macromolecule metabolic process GO:0060255 421 0.048
regulation of cell death GO:0010941 65 0.048
establishment of nucleus localization GO:0040023 55 0.048
multi organism reproductive behavior GO:0044705 387 0.047
small molecule metabolic process GO:0044281 186 0.047
cellular localization GO:0051641 360 0.046
Yeast
multicellular organismal reproductive behavior GO:0033057 384 0.045
neuron differentiation GO:0030182 217 0.045
glycosyl compound metabolic process GO:1901657 100 0.044
cellular macromolecule biosynthetic process GO:0034645 247 0.043
regulation of cell communication GO:0010646 176 0.042
behavior GO:0007610 527 0.041
cellular biosynthetic process GO:0044249 315 0.041
muscle cell development GO:0055001 158 0.041
Mouse Worm
cellular macromolecular complex assembly GO:0034622 184 0.041
Worm
multi multicellular organism process GO:0044706 390 0.038
generation of neurons GO:0048699 235 0.038
adult behavior GO:0030534 3 0.037
muscle organ development GO:0007517 26 0.037
Worm
muscle organ morphogenesis GO:0048644 4 0.037
head development GO:0060322 1 0.037
Human
transcription dna templated GO:0006351 168 0.036
body morphogenesis GO:0010171 620 0.035
muscle structure development GO:0061061 191 0.035
Mouse Worm
actin filament based process GO:0030029 191 0.035
Mouse Worm
sensory organ morphogenesis GO:0090596 2 0.035
nucleobase containing compound catabolic process GO:0034655 114 0.035
cellular macromolecule localization GO:0070727 75 0.035
cell recognition GO:0008037 85 0.035
rna metabolic process GO:0016070 228 0.034
organelle assembly GO:0070925 214 0.034
Mouse Worm
response to unfolded protein GO:0006986 71 0.034
myosin filament organization GO:0031033 138 0.033
Worm
mitotic nuclear division GO:0007067 89 0.033
single organism behavior GO:0044708 83 0.033
nuclear pore distribution GO:0031081 2 0.032
organ morphogenesis GO:0009887 67 0.032
regulation of primary metabolic process GO:0080090 292 0.031
protein metabolic process GO:0019538 422 0.031
Yeast
regulation of signal transduction GO:0009966 135 0.031
nucleobase containing compound metabolic process GO:0006139 406 0.030
Yeast
rna biosynthetic process GO:0032774 169 0.030
ion homeostasis GO:0050801 21 0.029
cell division GO:0051301 262 0.028
Yeast Worm
regulation of apoptotic signaling pathway GO:2001233 1 0.028
heterocycle biosynthetic process GO:0018130 187 0.028
myofibril assembly GO:0030239 154 0.027
Mouse Worm
phagocytosis GO:0006909 115 0.026
single organism transport GO:0044765 447 0.026
Yeast
cellular response to stress GO:0033554 162 0.025
Yeast
regulation of gene expression GO:0010468 366 0.025
carbohydrate derivative metabolic process GO:1901135 141 0.025
regulation of nucleocytoplasmic transport GO:0046822 3 0.024
apoptotic cell clearance GO:0043277 111 0.024
cell surface receptor signaling pathway GO:0007166 149 0.024
regulation of programmed cell death GO:0043067 50 0.024
ribonucleoside triphosphate catabolic process GO:0009203 72 0.024
epithelial tube morphogenesis GO:0060562 1 0.024
multi organism behavior GO:0051705 389 0.024
regulation of biosynthetic process GO:0009889 189 0.023
cellular protein metabolic process GO:0044267 279 0.023
Yeast
establishment of localization in cell GO:0051649 318 0.023
Yeast
regulation of signaling GO:0023051 172 0.023
positive regulation of cell death GO:0010942 38 0.023
myosin filament assembly GO:0031034 138 0.022
Worm
neurogenesis GO:0022008 236 0.022
nucleic acid metabolic process GO:0090304 299 0.022
Yeast
regulation of cellular component organization GO:0051128 248 0.022
actomyosin structure organization GO:0031032 154 0.022
Mouse Worm
regulation of lipid metabolic process GO:0019216 4 0.022
purine nucleoside metabolic process GO:0042278 92 0.022
negative regulation of cellular process GO:0048523 239 0.021
cellular homeostasis GO:0019725 22 0.021
negative regulation of metabolic process GO:0009892 240 0.021
negative regulation of macromolecule metabolic process GO:0010605 229 0.020
negative regulation of vulval development GO:0040027 206 0.020
cuticle development GO:0042335 100 0.020
regulation of cellular metabolic process GO:0031323 305 0.020
nucleobase containing compound biosynthetic process GO:0034654 184 0.019
cytokinesis GO:0000910 80 0.019
Yeast Worm
phagocytosis engulfment GO:0006911 98 0.019
nucleoside catabolic process GO:0009164 78 0.019
microtubule based process GO:0007017 182 0.018
nucleoside phosphate catabolic process GO:1901292 77 0.018
nucleoside metabolic process GO:0009116 99 0.018
regulation of cell proliferation GO:0042127 105 0.018
organophosphate metabolic process GO:0019637 125 0.018
positive regulation of signal transduction GO:0009967 40 0.018
aromatic compound biosynthetic process GO:0019438 192 0.018
axon development GO:0061564 163 0.018
negative regulation of multicellular organismal process GO:0051241 236 0.018
regulation of nitrogen compound metabolic process GO:0051171 222 0.018
establishment of spindle localization GO:0051293 51 0.018
cell proliferation GO:0008283 116 0.018
membrane invagination GO:0010324 98 0.017
intracellular transport GO:0046907 77 0.016
phosphorus metabolic process GO:0006793 232 0.016
regulation of locomotion GO:0040012 161 0.016
spindle localization GO:0051653 51 0.016
organic cyclic compound biosynthetic process GO:1901362 195 0.016
negative regulation of gene expression GO:0010629 217 0.016
organonitrogen compound metabolic process GO:1901564 151 0.016
negative regulation of developmental process GO:0051093 227 0.016
response to acid chemical GO:0001101 4 0.015
regulation of nematode larval development GO:0061062 260 0.015
chromosome segregation GO:0007059 180 0.015
organonitrogen compound catabolic process GO:1901565 90 0.015
protein localization GO:0008104 205 0.015
Yeast
regulation of transcription dna templated GO:0006355 164 0.015
oviposition GO:0018991 364 0.015
nucleic acid templated transcription GO:0097659 169 0.015
response to wounding GO:0009611 4 0.015
Human
cellular protein localization GO:0034613 75 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.015
gene silencing GO:0016458 143 0.015
purine nucleoside triphosphate metabolic process GO:0009144 87 0.014
organic acid biosynthetic process GO:0016053 21 0.014
cell projection assembly GO:0030031 35 0.014
neuron development GO:0048666 199 0.014
innate immune response GO:0045087 190 0.014
regulation of rna biosynthetic process GO:2001141 165 0.014
mitochondrion organization GO:0007005 20 0.014
regulation of localization GO:0032879 194 0.014
male sex differentiation GO:0046661 86 0.014
lipid metabolic process GO:0006629 77 0.014
organic substance transport GO:0071702 113 0.013
Yeast
tissue development GO:0009888 112 0.013
regulation of multicellular organismal development GO:2000026 317 0.013
regulation of protein localization GO:0032880 50 0.013
organic cyclic compound catabolic process GO:1901361 119 0.013
organic acid metabolic process GO:0006082 47 0.013
amine metabolic process GO:0009308 15 0.013
regulation of apoptotic process GO:0042981 36 0.013
regulation of vulval development GO:0040028 248 0.012
response to organic substance GO:0010033 131 0.012
transmembrane transport GO:0055085 110 0.012
positive regulation of macromolecule metabolic process GO:0010604 149 0.012
regulation of macromolecule biosynthetic process GO:0010556 189 0.012
engulfment of apoptotic cell GO:0043652 94 0.012
regulation of protein targeting GO:1903533 3 0.012
regulation of organelle organization GO:0033043 164 0.012
positive regulation of biosynthetic process GO:0009891 109 0.012
regulation of transport GO:0051049 91 0.012
positive regulation of cysteine type endopeptidase activity GO:2001056 3 0.012
neuron recognition GO:0008038 83 0.012
ribonucleotide catabolic process GO:0009261 75 0.012
regulation of post embryonic development GO:0048580 260 0.012
purine nucleotide catabolic process GO:0006195 75 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.011
hormone metabolic process GO:0042445 3 0.011
embryonic morphogenesis GO:0048598 152 0.011
regulation of cell motility GO:2000145 57 0.011
establishment or maintenance of cell polarity GO:0007163 63 0.011
Yeast
regulation of cellular amine metabolic process GO:0033238 0 0.011
cellular amine metabolic process GO:0044106 15 0.011
glycosyl compound catabolic process GO:1901658 79 0.010
response to other organism GO:0051707 101 0.010
nucleoside phosphate metabolic process GO:0006753 108 0.010
apoptotic mitochondrial changes GO:0008637 2 0.010
cellular hormone metabolic process GO:0034754 1 0.010

act-5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.059
muscular disease DOID:0080000 0 0.059
heart disease DOID:114 0 0.059
cardiomyopathy DOID:0050700 0 0.059
dilated cardiomyopathy DOID:12930 0 0.059
disease of anatomical entity DOID:7 0 0.059
Human
intrinsic cardiomyopathy DOID:0060036 0 0.059
cardiovascular system disease DOID:1287 0 0.059
musculoskeletal system disease DOID:17 0 0.059
muscle tissue disease DOID:66 0 0.059
congenital muscular dystrophy DOID:0050557 0 0.028
muscular dystrophy DOID:9884 0 0.028
nervous system disease DOID:863 0 0.018
Human
neuromuscular disease DOID:440 0 0.014
charcot marie tooth disease type 2 DOID:0050539 0 0.014
charcot marie tooth disease DOID:10595 0 0.014
neuropathy DOID:870 0 0.014
lipodystrophy DOID:811 0 0.013
skin disease DOID:37 0 0.013
integumentary system disease DOID:16 0 0.013
familial partial lipodystrophy DOID:0050440 0 0.013