Caenorhabditis elegans

116 known processes

end-1 (CELE_F58E10.2)

Protein END-1

end-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.439
post embryonic development GO:0009791 2152 0.330
embryo development ending in birth or egg hatching GO:0009792 2992 0.307
hermaphrodite genitalia development GO:0040035 734 0.215
single organism reproductive process GO:0044702 1196 0.208
developmental process involved in reproduction GO:0003006 1165 0.182
multicellular organism reproduction GO:0032504 819 0.179
Worm
reproductive structure development GO:0048608 850 0.158
gonad development GO:0008406 840 0.154
reproductive system development GO:0061458 850 0.154
multicellular organismal reproductive process GO:0048609 815 0.154
Worm
organ development GO:0048513 1102 0.151
development of primary sexual characteristics GO:0045137 840 0.147
locomotion GO:0040011 1634 0.138
sex differentiation GO:0007548 909 0.135
multi multicellular organism process GO:0044706 390 0.127
Worm
body morphogenesis GO:0010171 620 0.125
Worm
regulation of metabolic process GO:0019222 478 0.121
oviposition GO:0018991 364 0.118
Worm
multi organism reproductive process GO:0044703 867 0.117
Worm
multicellular organismal reproductive behavior GO:0033057 384 0.106
Worm
regulation of biological quality GO:0065008 741 0.104
endocytosis GO:0006897 819 0.090
multi organism reproductive behavior GO:0044705 387 0.087
Worm
genitalia development GO:0048806 741 0.086
transport GO:0006810 1093 0.086
multicellular organismal aging GO:0010259 812 0.084
Worm
multi organism behavior GO:0051705 389 0.082
Worm
determination of adult lifespan GO:0008340 812 0.080
Worm
positive regulation of developmental process GO:0051094 408 0.080
Worm
reproductive behavior GO:0019098 387 0.076
Worm
localization of cell GO:0051674 313 0.076
vesicle mediated transport GO:0016192 852 0.074
macromolecule localization GO:0033036 771 0.072
regulation of cellular biosynthetic process GO:0031326 189 0.071
growth GO:0040007 562 0.070
Worm
regulation of multicellular organismal process GO:0051239 726 0.070
Worm
cell development GO:0048468 696 0.070
Worm
developmental growth GO:0048589 412 0.067
Worm
regulation of developmental process GO:0050793 684 0.067
Worm
receptor mediated endocytosis GO:0006898 715 0.067
head development GO:0060322 1 0.067
post embryonic organ development GO:0048569 336 0.065
cellular biosynthetic process GO:0044249 315 0.065
maintenance of location GO:0051235 580 0.064
lipid localization GO:0010876 573 0.064
behavior GO:0007610 527 0.064
Worm
lipid storage GO:0019915 565 0.062
negative regulation of metabolic process GO:0009892 240 0.062
nervous system development GO:0007399 253 0.061
aging GO:0007568 812 0.058
Worm
regulation of growth GO:0040008 409 0.057
Worm
cell death GO:0008219 547 0.056
vulval development GO:0040025 333 0.056
transcription from rna polymerase ii promoter GO:0006366 149 0.054
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.053
negative regulation of biological process GO:0048519 567 0.053
cell division GO:0051301 262 0.053
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.052
heterocycle biosynthetic process GO:0018130 187 0.051
positive regulation of macromolecule metabolic process GO:0010604 149 0.051
regulation of macromolecule metabolic process GO:0060255 421 0.051
macromolecule biosynthetic process GO:0009059 250 0.051
regulation of developmental growth GO:0048638 389 0.051
Worm
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.051
positive regulation of growth GO:0045927 369 0.051
Worm
transcription dna templated GO:0006351 168 0.050
organelle fission GO:0048285 363 0.049
establishment of localization GO:0051234 1171 0.049
regulation of nematode larval development GO:0061062 260 0.049
organelle organization GO:0006996 783 0.049
Worm
cellular component movement GO:0006928 388 0.049
regulation of rna metabolic process GO:0051252 173 0.048
negative regulation of gene expression GO:0010629 217 0.048
multicellular organism growth GO:0035264 385 0.048
Worm
regulation of gene expression GO:0010468 366 0.047
regulation of rna biosynthetic process GO:2001141 165 0.047
phosphorus metabolic process GO:0006793 232 0.047
germ cell development GO:0007281 351 0.046
nucleobase containing compound metabolic process GO:0006139 406 0.046
regulation of multicellular organism growth GO:0040014 373 0.046
Worm
cell motility GO:0048870 313 0.046
death GO:0016265 547 0.045
protein metabolic process GO:0019538 422 0.045
biosynthetic process GO:0009058 323 0.044
muscle tissue development GO:0060537 1 0.044
positive regulation of multicellular organismal process GO:0051240 417 0.042
Worm
neuron differentiation GO:0030182 217 0.042
positive regulation of multicellular organism growth GO:0040018 352 0.042
Worm
cell cycle process GO:0022402 482 0.041
regulation of cellular component organization GO:0051128 248 0.041
cellular macromolecule biosynthetic process GO:0034645 247 0.040
negative regulation of post embryonic development GO:0048581 208 0.040
cell migration GO:0016477 306 0.039
nucleic acid templated transcription GO:0097659 169 0.039
catabolic process GO:0009056 318 0.038
female gamete generation GO:0007292 254 0.038
apoptotic process GO:0006915 478 0.037
regulation of vulval development GO:0040028 248 0.037
response to wounding GO:0009611 4 0.037
neurogenesis GO:0022008 236 0.037
programmed cell death GO:0012501 500 0.037
regulation of nucleic acid templated transcription GO:1903506 165 0.036
regulation of locomotion GO:0040012 161 0.036
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.035
regulation of post embryonic development GO:0048580 260 0.035
gene expression GO:0010467 412 0.035
regulation of multicellular organismal development GO:2000026 317 0.034
Worm
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.034
response to external stimulus GO:0009605 289 0.034
Worm
nucleic acid metabolic process GO:0090304 299 0.034
cellular component assembly GO:0022607 293 0.034
Worm
cell cycle GO:0007049 526 0.033
protein complex subunit organization GO:0071822 280 0.033
Worm
organic cyclic compound biosynthetic process GO:1901362 195 0.033
macromolecular complex subunit organization GO:0043933 320 0.033
Worm
negative regulation of multicellular organismal process GO:0051241 236 0.033
positive regulation of developmental growth GO:0048639 354 0.032
Worm
oogenesis GO:0048477 229 0.032
response to abiotic stimulus GO:0009628 152 0.032
Worm
gamete generation GO:0007276 461 0.031
Worm
regulation of cellular metabolic process GO:0031323 305 0.031
regulation of nitrogen compound metabolic process GO:0051171 222 0.030
phosphate containing compound metabolic process GO:0006796 232 0.030
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.029
Worm
cell type specific apoptotic process GO:0097285 4 0.029
cellular component biogenesis GO:0044085 297 0.029
Worm
negative regulation of nematode larval development GO:0061064 208 0.028
response to chemical GO:0042221 356 0.028
molting cycle GO:0042303 281 0.028
Worm
meiotic nuclear division GO:0007126 300 0.028
negative regulation of biosynthetic process GO:0009890 65 0.028
rna metabolic process GO:0016070 228 0.028
negative regulation of vulval development GO:0040027 206 0.027
macromolecule modification GO:0043412 218 0.027
muscle organ morphogenesis GO:0048644 4 0.027
regulation of primary metabolic process GO:0080090 292 0.027
organic substance biosynthetic process GO:1901576 323 0.026
macromolecular complex assembly GO:0065003 193 0.026
Worm
cellular protein modification process GO:0006464 207 0.026
positive regulation of neurogenesis GO:0050769 4 0.025
sexual reproduction GO:0019953 546 0.025
Worm
regulation of cell cycle GO:0051726 194 0.024
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.024
single organism signaling GO:0044700 401 0.024
protein complex biogenesis GO:0070271 186 0.024
Worm
regulation of cell cycle process GO:0010564 145 0.023
rna biosynthetic process GO:0032774 169 0.023
system process GO:0003008 136 0.023
cellular nitrogen compound biosynthetic process GO:0044271 192 0.023
meiotic chromosome segregation GO:0045132 139 0.023
nucleobase containing compound biosynthetic process GO:0034654 184 0.023
ribonucleoprotein complex assembly GO:0022618 4 0.023
embryonic morphogenesis GO:0048598 152 0.022
positive regulation of rna metabolic process GO:0051254 103 0.022
regulation of organ morphogenesis GO:2000027 4 0.022
meiotic cell cycle GO:0051321 335 0.022
cellular protein metabolic process GO:0044267 279 0.022
digestive system development GO:0055123 122 0.022
neuron development GO:0048666 199 0.021
regulation of biosynthetic process GO:0009889 189 0.021
organic substance catabolic process GO:1901575 294 0.021
aromatic compound biosynthetic process GO:0019438 192 0.021
cellular catabolic process GO:0044248 199 0.021
regulation of signal transduction GO:0009966 135 0.021
protein modification process GO:0036211 207 0.021
anatomical structure formation involved in morphogenesis GO:0048646 250 0.021
positive regulation of metabolic process GO:0009893 187 0.020
signaling GO:0023052 401 0.020
regulation of mitotic cell cycle GO:0007346 76 0.020
regulation of localization GO:0032879 194 0.020
immune response GO:0006955 192 0.020
Worm
single organism localization GO:1902578 518 0.020
meiotic cell cycle process GO:1903046 170 0.020
regulation of response to stimulus GO:0048583 243 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.020
regulation of transcription dna templated GO:0006355 164 0.020
digestive tract development GO:0048565 122 0.020
regulation of anatomical structure size GO:0090066 46 0.020
protein complex assembly GO:0006461 186 0.020
Worm
regulation of behavior GO:0050795 97 0.020
cell projection organization GO:0030030 231 0.020
cellular component morphogenesis GO:0032989 318 0.019
Worm
cellular localization GO:0051641 360 0.019
cell recognition GO:0008037 85 0.019
posttranscriptional regulation of gene expression GO:0010608 166 0.019
small molecule metabolic process GO:0044281 186 0.019
inductive cell migration GO:0040039 145 0.019
generation of neurons GO:0048699 235 0.019
cellular macromolecular complex assembly GO:0034622 184 0.019
Worm
cell surface receptor signaling pathway GO:0007166 149 0.019
negative regulation of rna biosynthetic process GO:1902679 53 0.019
posttranscriptional gene silencing by rna GO:0035194 143 0.018
negative regulation of macromolecule metabolic process GO:0010605 229 0.018
mitotic cell cycle process GO:1903047 194 0.018
positive regulation of neuron differentiation GO:0045666 4 0.018
collagen and cuticulin based cuticle development GO:0040002 99 0.018
Worm
epithelium development GO:0060429 68 0.018
Worm
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.018
cell proliferation GO:0008283 116 0.018
macromolecule catabolic process GO:0009057 202 0.018
negative regulation of cellular metabolic process GO:0031324 95 0.018
sensory organ morphogenesis GO:0090596 2 0.018
regulation of organelle organization GO:0033043 164 0.017
positive regulation of nucleic acid templated transcription GO:1903508 102 0.017
memory GO:0007613 3 0.017
regulation of oviposition GO:0046662 43 0.017
cellular protein complex assembly GO:0043623 178 0.017
Worm
positive regulation of cellular metabolic process GO:0031325 178 0.017
gene silencing by rna GO:0031047 143 0.017
negative regulation of cellular biosynthetic process GO:0031327 65 0.017
defense response GO:0006952 296 0.016
Worm
regulation of lipid metabolic process GO:0019216 4 0.016
positive regulation of transcription dna templated GO:0045893 102 0.016
regulation of gene expression epigenetic GO:0040029 163 0.016
negative regulation of nucleic acid templated transcription GO:1903507 53 0.016
cellular response to stress GO:0033554 162 0.016
Worm
establishment of localization in cell GO:0051649 318 0.016
single organism organelle organization GO:1902589 501 0.016
Worm
chromosome segregation GO:0007059 180 0.016
organonitrogen compound metabolic process GO:1901564 151 0.016
muscle cell development GO:0055001 158 0.016
Worm
striated muscle cell differentiation GO:0051146 158 0.016
Worm
regulation of macromolecule biosynthetic process GO:0010556 189 0.016
cell fate commitment GO:0045165 139 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
single organism catabolic process GO:0044712 129 0.015
gene silencing GO:0016458 143 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.015
skeletal muscle organ development GO:0060538 3 0.015
regulation of reproductive process GO:2000241 66 0.015
posttranscriptional gene silencing GO:0016441 143 0.015
epithelial tube morphogenesis GO:0060562 1 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.015
digestive tract morphogenesis GO:0048546 76 0.015
negative regulation of developmental process GO:0051093 227 0.015
rna interference GO:0016246 137 0.014
axon development GO:0061564 163 0.014
positive regulation of cellular process GO:0048522 332 0.014
chemotaxis GO:0006935 120 0.014
tube morphogenesis GO:0035239 79 0.014
myosin filament organization GO:0031033 138 0.014
Worm
regulation of protein metabolic process GO:0051246 81 0.014
tissue development GO:0009888 112 0.014
fertilization GO:0009566 63 0.014
positive regulation of rna biosynthetic process GO:1902680 102 0.014
protein phosphorylation GO:0006468 85 0.014
oxoacid metabolic process GO:0043436 47 0.014
signal transduction GO:0007165 317 0.014
positive regulation of gene expression GO:0010628 112 0.014
cytoskeleton organization GO:0007010 339 0.013
Worm
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.013
regulation of cell proliferation GO:0042127 105 0.013
neuron projection development GO:0031175 187 0.013
single organism transport GO:0044765 447 0.013
cellular response to abiotic stimulus GO:0071214 4 0.013
Worm
striated muscle myosin thick filament assembly GO:0071688 138 0.013
Worm
muscle cell differentiation GO:0042692 171 0.013
Worm
regulation of cell division GO:0051302 142 0.013
cuticle development GO:0042335 100 0.012
Worm
response to acid chemical GO:0001101 4 0.012
myofibril assembly GO:0030239 154 0.012
Worm
positive regulation of cell cycle GO:0045787 55 0.012
actin filament based process GO:0030029 191 0.012
Worm
secretion GO:0046903 147 0.012
myosin filament assembly GO:0031034 138 0.012
Worm
intracellular receptor signaling pathway GO:0030522 2 0.012
cellular component assembly involved in morphogenesis GO:0010927 183 0.012
Worm
establishment of cell polarity GO:0030010 46 0.012
negative regulation of transcription dna templated GO:0045892 53 0.012
regulation of cytoplasmic transport GO:1903649 3 0.012
response to external biotic stimulus GO:0043207 101 0.012
Worm
regulation of cellular amine metabolic process GO:0033238 0 0.011
neuron recognition GO:0008038 83 0.011
regulation of cellular component size GO:0032535 40 0.011
regeneration GO:0031099 4 0.011
actin cytoskeleton organization GO:0030036 184 0.011
Worm
regulation of apoptotic signaling pathway GO:2001233 1 0.011
synaptic target recognition GO:0008039 3 0.011
regulation of gastrulation GO:0010470 4 0.011
muscle structure development GO:0061061 191 0.011
Worm
cytokinesis GO:0000910 80 0.011
cellular ketone metabolic process GO:0042180 14 0.011
regulation of cellular component movement GO:0051270 62 0.011
phosphorylation GO:0016310 116 0.011
negative regulation of neurogenesis GO:0050768 4 0.011
dna metabolic process GO:0006259 74 0.011
carboxylic acid metabolic process GO:0019752 34 0.011
response to organic substance GO:0010033 131 0.011
response to other organism GO:0051707 101 0.011
Worm
organic acid metabolic process GO:0006082 47 0.011
negative regulation of cell cycle GO:0045786 53 0.011
single fertilization GO:0007338 61 0.011
regulation of nuclear division GO:0051783 115 0.010
organelle localization GO:0051640 127 0.010
chromosome organization GO:0051276 104 0.010
chromatin assembly or disassembly GO:0006333 1 0.010
cellular amino acid metabolic process GO:0006520 15 0.010
mrna metabolic process GO:0016071 31 0.010
protein localization GO:0008104 205 0.010
regulation of response to wounding GO:1903034 1 0.010

end-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.011