Caenorhabditis elegans

44 known processes

vars-2 (CELE_Y87G2A.5)

Protein VARS-2

vars-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.697
embryo development ending in birth or egg hatching GO:0009792 2992 0.674
post embryonic development GO:0009791 2152 0.475
gene expression GO:0010467 412 0.265
transport GO:0006810 1093 0.230
locomotion GO:0040011 1634 0.183
regulation of multicellular organismal process GO:0051239 726 0.164
receptor mediated endocytosis GO:0006898 715 0.150
establishment of localization GO:0051234 1171 0.144
single organism reproductive process GO:0044702 1196 0.142
regulation of gene expression GO:0010468 366 0.102
organ development GO:0048513 1102 0.099
organic substance biosynthetic process GO:1901576 323 0.097
death GO:0016265 547 0.096
positive regulation of developmental process GO:0051094 408 0.085
negative regulation of biological process GO:0048519 567 0.080
regulation of biological quality GO:0065008 741 0.078
organelle organization GO:0006996 783 0.072
growth GO:0040007 562 0.072
positive regulation of growth GO:0045927 369 0.070
positive regulation of cellular process GO:0048522 332 0.066
body morphogenesis GO:0010171 620 0.065
aging GO:0007568 812 0.061
sex differentiation GO:0007548 909 0.060
pronuclear migration GO:0035046 51 0.059
lipid storage GO:0019915 565 0.059
fertilization GO:0009566 63 0.058
maintenance of location GO:0051235 580 0.057
macromolecule localization GO:0033036 771 0.056
cellular component movement GO:0006928 388 0.056
lipid localization GO:0010876 573 0.056
posttranscriptional regulation of gene expression GO:0010608 166 0.056
actin filament based process GO:0030029 191 0.056
single organism transport GO:0044765 447 0.055
vesicle mediated transport GO:0016192 852 0.055
cell death GO:0008219 547 0.054
single organism signaling GO:0044700 401 0.053
positive regulation of developmental growth GO:0048639 354 0.053
multicellular organismal aging GO:0010259 812 0.053
regulation of cellular metabolic process GO:0031323 305 0.052
multi organism reproductive process GO:0044703 867 0.051
cellular localization GO:0051641 360 0.051
developmental growth GO:0048589 412 0.051
reproductive structure development GO:0048608 850 0.050
negative regulation of metabolic process GO:0009892 240 0.050
regulation of multicellular organism growth GO:0040014 373 0.049
regulation of metabolic process GO:0019222 478 0.048
reproductive behavior GO:0019098 387 0.048
cellular component assembly GO:0022607 293 0.047
positive regulation of multicellular organismal process GO:0051240 417 0.046
single fertilization GO:0007338 61 0.046
regulation of developmental process GO:0050793 684 0.046
response to chemical GO:0042221 356 0.045
regulation of growth GO:0040008 409 0.045
multicellular organism reproduction GO:0032504 819 0.045
gonad development GO:0008406 840 0.045
programmed cell death GO:0012501 500 0.044
endocytosis GO:0006897 819 0.044
macromolecular complex assembly GO:0065003 193 0.043
reproductive system development GO:0061458 850 0.043
developmental process involved in reproduction GO:0003006 1165 0.042
cell development GO:0048468 696 0.041
response to external stimulus GO:0009605 289 0.041
cellular protein metabolic process GO:0044267 279 0.041
phagocytosis GO:0006909 115 0.040
single organism localization GO:1902578 518 0.039
determination of adult lifespan GO:0008340 812 0.038
cellular component morphogenesis GO:0032989 318 0.038
defense response GO:0006952 296 0.038
biosynthetic process GO:0009058 323 0.037
development of primary sexual characteristics GO:0045137 840 0.037
signaling GO:0023052 401 0.037
apoptotic process GO:0006915 478 0.036
cellular component biogenesis GO:0044085 297 0.036
establishment of organelle localization GO:0051656 123 0.036
multi organism behavior GO:0051705 389 0.036
regulation of macromolecule metabolic process GO:0060255 421 0.035
behavior GO:0007610 527 0.035
gene silencing by rna GO:0031047 143 0.035
cellular biosynthetic process GO:0044249 315 0.034
secretion by cell GO:0032940 138 0.034
positive regulation of multicellular organism growth GO:0040018 352 0.034
molting cycle GO:0042303 281 0.034
multi organism reproductive behavior GO:0044705 387 0.034
macromolecular complex subunit organization GO:0043933 320 0.033
phosphorus metabolic process GO:0006793 232 0.033
protein complex subunit organization GO:0071822 280 0.033
multicellular organismal reproductive behavior GO:0033057 384 0.033
negative regulation of macromolecule metabolic process GO:0010605 229 0.032
sexual reproduction GO:0019953 546 0.032
establishment of localization in cell GO:0051649 318 0.031
cell cycle process GO:0022402 482 0.031
translation GO:0006412 37 0.031
muscle tissue development GO:0060537 1 0.030
cell division GO:0051301 262 0.030
macromolecule biosynthetic process GO:0009059 250 0.030
cellular macromolecular complex assembly GO:0034622 184 0.030
rna interference GO:0016246 137 0.030
immune response GO:0006955 192 0.030
striated muscle cell development GO:0055002 157 0.030
organelle fission GO:0048285 363 0.030
oviposition GO:0018991 364 0.029
cell migration GO:0016477 306 0.029
multi multicellular organism process GO:0044706 390 0.029
single organism organelle organization GO:1902589 501 0.029
gene silencing GO:0016458 143 0.029
multicellular organismal reproductive process GO:0048609 815 0.029
regulation of primary metabolic process GO:0080090 292 0.028
striated muscle cell differentiation GO:0051146 158 0.028
organelle localization GO:0051640 127 0.028
muscle structure development GO:0061061 191 0.028
posttranscriptional gene silencing GO:0016441 143 0.028
phosphate containing compound metabolic process GO:0006796 232 0.027
muscle cell differentiation GO:0042692 171 0.027
response to wounding GO:0009611 4 0.026
genitalia development GO:0048806 741 0.026
cellular component assembly involved in morphogenesis GO:0010927 183 0.026
generation of neurons GO:0048699 235 0.026
posttranscriptional gene silencing by rna GO:0035194 143 0.025
protein metabolic process GO:0019538 422 0.025
macromolecule catabolic process GO:0009057 202 0.025
regulation of multicellular organismal development GO:2000026 317 0.024
nucleobase containing compound metabolic process GO:0006139 406 0.024
regulation of developmental growth GO:0048638 389 0.024
protein complex biogenesis GO:0070271 186 0.024
signal transduction GO:0007165 317 0.024
anatomical structure formation involved in morphogenesis GO:0048646 250 0.024
apoptotic cell clearance GO:0043277 111 0.024
cell proliferation GO:0008283 116 0.024
cytoskeleton organization GO:0007010 339 0.023
epithelial tube morphogenesis GO:0060562 1 0.023
regulation of gene expression epigenetic GO:0040029 163 0.023
nervous system development GO:0007399 253 0.023
head development GO:0060322 1 0.023
small molecule metabolic process GO:0044281 186 0.023
innate immune response GO:0045087 190 0.023
neuron differentiation GO:0030182 217 0.023
cell motility GO:0048870 313 0.022
macromolecule modification GO:0043412 218 0.022
secretion GO:0046903 147 0.022
cell cycle GO:0007049 526 0.021
protein complex assembly GO:0006461 186 0.021
regulation of response to stimulus GO:0048583 243 0.021
oxoacid metabolic process GO:0043436 47 0.021
regulation of nitrogen compound metabolic process GO:0051171 222 0.020
cell morphogenesis GO:0000902 163 0.020
negative regulation of gene expression GO:0010629 217 0.020
organic acid metabolic process GO:0006082 47 0.019
regulation of cellular protein metabolic process GO:0032268 75 0.019
muscle cell development GO:0055001 158 0.019
regulation of post embryonic development GO:0048580 260 0.019
myosin filament organization GO:0031033 138 0.019
membrane invagination GO:0010324 98 0.019
myosin filament assembly GO:0031034 138 0.019
multicellular organism growth GO:0035264 385 0.019
transmembrane transport GO:0055085 110 0.019
regulation of cell proliferation GO:0042127 105 0.018
positive regulation of cell projection organization GO:0031346 4 0.018
membrane organization GO:0061024 135 0.018
establishment of nucleus localization GO:0040023 55 0.018
female gamete generation GO:0007292 254 0.017
cellular protein complex assembly GO:0043623 178 0.017
regulation of cellular biosynthetic process GO:0031326 189 0.017
localization of cell GO:0051674 313 0.017
organonitrogen compound metabolic process GO:1901564 151 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.016
protein oligomerization GO:0051259 4 0.016
positive regulation of cellular metabolic process GO:0031325 178 0.016
nucleic acid metabolic process GO:0090304 299 0.016
regulation of vulval development GO:0040028 248 0.016
negative regulation of nematode larval development GO:0061064 208 0.016
negative regulation of cellular process GO:0048523 239 0.015
regulation of lipid metabolic process GO:0019216 4 0.015
response to abiotic stimulus GO:0009628 152 0.015
cuticle development GO:0042335 100 0.015
engulfment of apoptotic cell GO:0043652 94 0.015
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.015
actomyosin structure organization GO:0031032 154 0.015
neurogenesis GO:0022008 236 0.015
myofibril assembly GO:0030239 154 0.015
cellular macromolecule biosynthetic process GO:0034645 247 0.015
vulval development GO:0040025 333 0.015
carboxylic acid metabolic process GO:0019752 34 0.015
mitotic nuclear division GO:0007067 89 0.014
organelle assembly GO:0070925 214 0.014
nuclear migration GO:0007097 54 0.014
epithelial cell proliferation GO:0050673 1 0.014
aromatic compound biosynthetic process GO:0019438 192 0.014
olfactory behavior GO:0042048 27 0.014
organic substance catabolic process GO:1901575 294 0.014
skeletal muscle organ development GO:0060538 3 0.014
cellular response to organic substance GO:0071310 119 0.013
chromosome segregation GO:0007059 180 0.013
striated muscle myosin thick filament assembly GO:0071688 138 0.013
embryonic morphogenesis GO:0048598 152 0.013
hermaphrodite genitalia development GO:0040035 734 0.013
negative regulation of vulval development GO:0040027 206 0.013
negative regulation of developmental process GO:0051093 227 0.013
regulation of synapse assembly GO:0051963 2 0.013
g protein coupled receptor signaling pathway GO:0007186 46 0.013
cell projection organization GO:0030030 231 0.012
phagocytosis engulfment GO:0006911 98 0.012
establishment of cell polarity GO:0030010 46 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.012
meiotic cell cycle GO:0051321 335 0.012
germ cell development GO:0007281 351 0.012
establishment or maintenance of cell polarity GO:0007163 63 0.012
establishment of protein localization to membrane GO:0090150 3 0.012
regulation of protein metabolic process GO:0051246 81 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
carbohydrate derivative metabolic process GO:1901135 141 0.012
catabolic process GO:0009056 318 0.012
axon development GO:0061564 163 0.012
meiotic nuclear division GO:0007126 300 0.011
positive regulation of protein metabolic process GO:0051247 45 0.011
positive regulation of metabolic process GO:0009893 187 0.011
ion transmembrane transport GO:0034220 91 0.011
actin cytoskeleton organization GO:0030036 184 0.011
tube development GO:0035295 126 0.011
regulation of protein stability GO:0031647 3 0.011
adult behavior GO:0030534 3 0.011
neuromuscular junction development GO:0007528 2 0.011
negative regulation of multicellular organismal process GO:0051241 236 0.011
cation transport GO:0006812 78 0.011
purine containing compound metabolic process GO:0072521 95 0.011
positive regulation of intracellular transport GO:0032388 2 0.010
regulation of macromolecule biosynthetic process GO:0010556 189 0.010
protein localization GO:0008104 205 0.010
response to external biotic stimulus GO:0043207 101 0.010
cell surface receptor signaling pathway GO:0007166 149 0.010

vars-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.124
nervous system disease DOID:863 0 0.023
musculoskeletal system disease DOID:17 0 0.018
neuromuscular disease DOID:440 0 0.012
neuropathy DOID:870 0 0.012