Caenorhabditis elegans

29 known processes

lem-2 (CELE_W01G7.5)

Protein LEM-2

lem-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.191
embryo development ending in birth or egg hatching GO:0009792 2992 0.188
post embryonic development GO:0009791 2152 0.176
single organism reproductive process GO:0044702 1196 0.138
locomotion GO:0040011 1634 0.101
Mouse
death GO:0016265 547 0.097
multi organism reproductive process GO:0044703 867 0.087
organelle organization GO:0006996 783 0.084
Mouse
transport GO:0006810 1093 0.083
cell development GO:0048468 696 0.081
developmental process involved in reproduction GO:0003006 1165 0.080
establishment of localization GO:0051234 1171 0.078
endocytosis GO:0006897 819 0.078
regulation of biological quality GO:0065008 741 0.077
aging GO:0007568 812 0.076
macromolecule localization GO:0033036 771 0.074
regulation of developmental process GO:0050793 684 0.070
cell death GO:0008219 547 0.068
receptor mediated endocytosis GO:0006898 715 0.066
programmed cell death GO:0012501 500 0.066
development of primary sexual characteristics GO:0045137 840 0.066
regulation of metabolic process GO:0019222 478 0.066
Fly
multicellular organism reproduction GO:0032504 819 0.066
vesicle mediated transport GO:0016192 852 0.066
maintenance of location GO:0051235 580 0.066
lipid localization GO:0010876 573 0.065
multicellular organismal reproductive process GO:0048609 815 0.064
lipid storage GO:0019915 565 0.061
organ development GO:0048513 1102 0.060
Mouse
negative regulation of biological process GO:0048519 567 0.057
Fly
gonad development GO:0008406 840 0.057
multicellular organismal aging GO:0010259 812 0.056
cell cycle GO:0007049 526 0.056
regulation of multicellular organismal process GO:0051239 726 0.056
hermaphrodite genitalia development GO:0040035 734 0.055
determination of adult lifespan GO:0008340 812 0.054
apoptotic process GO:0006915 478 0.053
positive regulation of multicellular organismal process GO:0051240 417 0.053
single organism organelle organization GO:1902589 501 0.052
cellular component movement GO:0006928 388 0.051
Mouse
reproductive structure development GO:0048608 850 0.051
growth GO:0040007 562 0.050
sexual reproduction GO:0019953 546 0.050
oogenesis GO:0048477 229 0.049
protein metabolic process GO:0019538 422 0.049
behavior GO:0007610 527 0.049
gamete generation GO:0007276 461 0.048
protein complex subunit organization GO:0071822 280 0.048
reproductive behavior GO:0019098 387 0.047
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.047
body morphogenesis GO:0010171 620 0.046
positive regulation of developmental process GO:0051094 408 0.045
multi multicellular organism process GO:0044706 390 0.045
developmental growth GO:0048589 412 0.045
sex differentiation GO:0007548 909 0.045
regulation of developmental growth GO:0048638 389 0.044
positive regulation of growth GO:0045927 369 0.043
multicellular organism growth GO:0035264 385 0.042
cytoskeleton organization GO:0007010 339 0.041
reproductive system development GO:0061458 850 0.041
regulation of growth GO:0040008 409 0.041
nucleobase containing compound metabolic process GO:0006139 406 0.040
genitalia development GO:0048806 741 0.040
single organism localization GO:1902578 518 0.040
positive regulation of developmental growth GO:0048639 354 0.038
regulation of cellular metabolic process GO:0031323 305 0.038
Fly
female gamete generation GO:0007292 254 0.037
vulval development GO:0040025 333 0.037
post embryonic organ development GO:0048569 336 0.036
multi organism reproductive behavior GO:0044705 387 0.036
cellular component morphogenesis GO:0032989 318 0.036
gene expression GO:0010467 412 0.036
germ cell development GO:0007281 351 0.036
multi organism behavior GO:0051705 389 0.035
macromolecular complex subunit organization GO:0043933 320 0.035
regulation of cell communication GO:0010646 176 0.034
Fly
establishment of localization in cell GO:0051649 318 0.033
single organism transport GO:0044765 447 0.033
regulation of vulval development GO:0040028 248 0.032
response to external stimulus GO:0009605 289 0.032
multicellular organismal reproductive behavior GO:0033057 384 0.032
protein modification process GO:0036211 207 0.031
response to chemical GO:0042221 356 0.030
cellular component assembly GO:0022607 293 0.030
regulation of post embryonic development GO:0048580 260 0.030
cell division GO:0051301 262 0.030
oviposition GO:0018991 364 0.030
cell cycle process GO:0022402 482 0.030
cellular protein metabolic process GO:0044267 279 0.030
signaling GO:0023052 401 0.029
Fly
actin cytoskeleton organization GO:0030036 184 0.029
regulation of primary metabolic process GO:0080090 292 0.029
Fly
regulation of multicellular organism growth GO:0040014 373 0.029
localization of cell GO:0051674 313 0.028
Mouse
regulation of gene expression epigenetic GO:0040029 163 0.028
cell projection morphogenesis GO:0048858 148 0.028
regulation of response to stimulus GO:0048583 243 0.028
Fly
cellular protein modification process GO:0006464 207 0.028
protein complex biogenesis GO:0070271 186 0.027
cellular component assembly involved in morphogenesis GO:0010927 183 0.027
neuron differentiation GO:0030182 217 0.027
positive regulation of multicellular organism growth GO:0040018 352 0.027
regulation of macromolecule metabolic process GO:0060255 421 0.027
Fly
posttranscriptional gene silencing GO:0016441 143 0.026
actin filament based process GO:0030029 191 0.026
cellular localization GO:0051641 360 0.026
small molecule metabolic process GO:0044281 186 0.025
regulation of multicellular organismal development GO:2000026 317 0.025
regulation of nitrogen compound metabolic process GO:0051171 222 0.025
Fly
cell projection organization GO:0030030 231 0.025
meiotic nuclear division GO:0007126 300 0.025
regulation of cell cycle GO:0051726 194 0.024
Mouse
single organism signaling GO:0044700 401 0.024
Fly
nervous system development GO:0007399 253 0.024
response to abiotic stimulus GO:0009628 152 0.024
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.024
cellular component biogenesis GO:0044085 297 0.024
actomyosin structure organization GO:0031032 154 0.024
gene silencing GO:0016458 143 0.023
macromolecular complex assembly GO:0065003 193 0.023
macromolecule modification GO:0043412 218 0.023
gene silencing by rna GO:0031047 143 0.023
neuron projection development GO:0031175 187 0.023
striated muscle cell development GO:0055002 157 0.023
muscle cell development GO:0055001 158 0.023
posttranscriptional gene silencing by rna GO:0035194 143 0.022
cellular protein complex assembly GO:0043623 178 0.022
striated muscle cell differentiation GO:0051146 158 0.022
cellular biosynthetic process GO:0044249 315 0.022
negative regulation of gene expression GO:0010629 217 0.022
molting cycle GO:0042303 281 0.022
regulation of cellular component organization GO:0051128 248 0.022
Mouse
regulation of gene expression GO:0010468 366 0.021
Fly
striated muscle myosin thick filament assembly GO:0071688 138 0.021
negative regulation of post embryonic development GO:0048581 208 0.021
neurogenesis GO:0022008 236 0.021
regulation of meiotic cell cycle GO:0051445 136 0.021
rna interference GO:0016246 137 0.021
protein complex assembly GO:0006461 186 0.021
meiotic cell cycle GO:0051321 335 0.021
organelle fission GO:0048285 363 0.021
myosin filament assembly GO:0031034 138 0.021
negative regulation of metabolic process GO:0009892 240 0.020
phosphate containing compound metabolic process GO:0006796 232 0.020
organic substance biosynthetic process GO:1901576 323 0.020
phosphorus metabolic process GO:0006793 232 0.020
negative regulation of multicellular organismal process GO:0051241 236 0.019
negative regulation of developmental process GO:0051093 227 0.019
negative regulation of nematode larval development GO:0061064 208 0.019
anatomical structure formation involved in morphogenesis GO:0048646 250 0.019
Mouse
myofibril assembly GO:0030239 154 0.019
posttranscriptional regulation of gene expression GO:0010608 166 0.019
positive regulation of cellular process GO:0048522 332 0.019
nucleic acid metabolic process GO:0090304 299 0.019
neuron development GO:0048666 199 0.019
myosin filament organization GO:0031033 138 0.019
ras protein signal transduction GO:0007265 31 0.019
response to wounding GO:0009611 4 0.018
cellular macromolecular complex assembly GO:0034622 184 0.018
neuron projection guidance GO:0097485 82 0.018
cell part morphogenesis GO:0032990 152 0.018
cell migration GO:0016477 306 0.018
Mouse
carbohydrate derivative metabolic process GO:1901135 141 0.018
regulation of cell division GO:0051302 142 0.018
organelle localization GO:0051640 127 0.018
positive regulation of nematode larval development GO:0061063 54 0.018
regulation of cytoplasmic transport GO:1903649 3 0.018
regulation of meiosis GO:0040020 94 0.018
protein localization GO:0008104 205 0.017
muscle structure development GO:0061061 191 0.017
Mouse
small gtpase mediated signal transduction GO:0007264 32 0.017
sensory organ morphogenesis GO:0090596 2 0.017
negative regulation of vulval development GO:0040027 206 0.017
regulation of nematode larval development GO:0061062 260 0.017
biosynthetic process GO:0009058 323 0.017
generation of neurons GO:0048699 235 0.016
negative regulation of macromolecule metabolic process GO:0010605 229 0.016
positive regulation of vulval development GO:0040026 52 0.016
positive regulation of post embryonic development GO:0048582 54 0.016
negative regulation of cellular process GO:0048523 239 0.016
Fly
organelle assembly GO:0070925 214 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.016
axon development GO:0061564 163 0.016
signal transduction GO:0007165 317 0.016
Fly
chromosome segregation GO:0007059 180 0.016
organonitrogen compound metabolic process GO:1901564 151 0.015
regulation of signaling GO:0023051 172 0.015
Fly
macromolecule biosynthetic process GO:0009059 250 0.015
regulation of cell proliferation GO:0042127 105 0.015
neuron projection morphogenesis GO:0048812 114 0.015
skeletal muscle organ development GO:0060538 3 0.015
Mouse
regulation of cell cycle process GO:0010564 145 0.015
establishment of organelle localization GO:0051656 123 0.015
catabolic process GO:0009056 318 0.015
cell proliferation GO:0008283 116 0.014
neuromuscular junction development GO:0007528 2 0.014
regulation of synapse assembly GO:0051963 2 0.014
cellular macromolecule biosynthetic process GO:0034645 247 0.014
regulation of localization GO:0032879 194 0.014
intracellular signal transduction GO:0035556 96 0.014
cell motility GO:0048870 313 0.014
Mouse
regulation of organelle organization GO:0033043 164 0.014
fertilization GO:0009566 63 0.014
cell surface receptor signaling pathway GO:0007166 149 0.014
Fly
regulation of signal transduction GO:0009966 135 0.014
Fly
positive regulation of cellular metabolic process GO:0031325 178 0.014
positive regulation of metabolic process GO:0009893 187 0.013
axonogenesis GO:0007409 102 0.013
chemotaxis GO:0006935 120 0.013
regulation of phosphate metabolic process GO:0019220 81 0.013
meiotic cell cycle process GO:1903046 170 0.013
regulation of epithelial cell proliferation GO:0050678 1 0.013
rna localization GO:0006403 3 0.013
regulation of nuclear division GO:0051783 115 0.013
cellular response to stress GO:0033554 162 0.013
organic substance transport GO:0071702 113 0.013
head development GO:0060322 1 0.013
epithelial tube morphogenesis GO:0060562 1 0.013
organic cyclic compound biosynthetic process GO:1901362 195 0.013
tube development GO:0035295 126 0.013
epithelial cell proliferation GO:0050673 1 0.013
taxis GO:0042330 128 0.013
secretion GO:0046903 147 0.013
negative regulation of neurogenesis GO:0050768 4 0.013
positive regulation of neurogenesis GO:0050769 4 0.013
regulation of phosphorus metabolic process GO:0051174 81 0.012
membrane organization GO:0061024 135 0.012
regulation of nucleocytoplasmic transport GO:0046822 3 0.012
cell morphogenesis involved in differentiation GO:0000904 112 0.012
organic substance catabolic process GO:1901575 294 0.012
microtubule based process GO:0007017 182 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
neuron recognition GO:0008038 83 0.012
cell type specific apoptotic process GO:0097285 4 0.012
regulation of apoptotic signaling pathway GO:2001233 1 0.012
nucleobase containing compound biosynthetic process GO:0034654 184 0.012
macromolecule catabolic process GO:0009057 202 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
axon guidance GO:0007411 82 0.012
regulation of locomotion GO:0040012 161 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.011
organophosphate metabolic process GO:0019637 125 0.011
adult behavior GO:0030534 3 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
muscle cell differentiation GO:0042692 171 0.011
cell recognition GO:0008037 85 0.011
regulation of protein import into nucleus GO:0042306 3 0.011
organic acid metabolic process GO:0006082 47 0.011
cellular nitrogen compound biosynthetic process GO:0044271 192 0.011
cytokinesis GO:0000910 80 0.011
rna metabolic process GO:0016070 228 0.011
regulation of protein targeting GO:1903533 3 0.011
regeneration GO:0031099 4 0.011
aromatic compound biosynthetic process GO:0019438 192 0.011
cellular amine metabolic process GO:0044106 15 0.011
oxoacid metabolic process GO:0043436 47 0.011
positive regulation of protein transport GO:0051222 4 0.011
rho protein signal transduction GO:0007266 2 0.011
meiotic chromosome segregation GO:0045132 139 0.011
cellular protein localization GO:0034613 75 0.011
phosphorylation GO:0016310 116 0.010
cell morphogenesis GO:0000902 163 0.010
protein oligomerization GO:0051259 4 0.010
amine metabolic process GO:0009308 15 0.010
chromatin remodeling GO:0006338 2 0.010
regulation of organ morphogenesis GO:2000027 4 0.010
axonal fasciculation GO:0007413 79 0.010
response to temperature stimulus GO:0009266 66 0.010
cellular macromolecule localization GO:0070727 75 0.010
establishment of nucleus localization GO:0040023 55 0.010
membrane invagination GO:0010324 98 0.010
collagen and cuticulin based cuticle development GO:0040002 99 0.010

lem-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.011
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010