Caenorhabditis elegans

35 known processes

let-19 (CELE_K08F8.6)

Protein LET-19

let-19 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
signaling GO:0023052 401 0.602
Human Fly
organelle organization GO:0006996 783 0.586
embryo development ending in birth or egg hatching GO:0009792 2992 0.582
developmental process involved in reproduction GO:0003006 1165 0.557
locomotion GO:0040011 1634 0.501
sex differentiation GO:0007548 909 0.483
regulation of vulval development GO:0040028 248 0.471
gonad development GO:0008406 840 0.405
multicellular organism reproduction GO:0032504 819 0.401
organ development GO:0048513 1102 0.363
cellular component morphogenesis GO:0032989 318 0.354
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.346
Human
reproductive structure development GO:0048608 850 0.340
regulation of multicellular organismal development GO:2000026 317 0.337
regulation of cellular component organization GO:0051128 248 0.331
hermaphrodite genitalia development GO:0040035 734 0.331
multicellular organismal reproductive behavior GO:0033057 384 0.319
body morphogenesis GO:0010171 620 0.317
embryo development GO:0009790 3052 0.305
negative regulation of vulval development GO:0040027 206 0.305
multi organism reproductive process GO:0044703 867 0.293
regulation of signaling GO:0023051 172 0.285
Fly
development of primary sexual characteristics GO:0045137 840 0.281
multi multicellular organism process GO:0044706 390 0.279
post embryonic development GO:0009791 2152 0.272
cell migration GO:0016477 306 0.271
cell cycle process GO:0022402 482 0.266
oviposition GO:0018991 364 0.255
positive regulation of locomotion GO:0040017 42 0.254
establishment of localization GO:0051234 1171 0.254
positive regulation of jnk cascade GO:0046330 3 0.246
transport GO:0006810 1093 0.245
multicellular organismal reproductive process GO:0048609 815 0.235
regulation of macromolecule metabolic process GO:0060255 421 0.230
Human Fly
reproductive behavior GO:0019098 387 0.212
regulation of nematode larval development GO:0061062 260 0.211
cell cycle GO:0007049 526 0.210
cell development GO:0048468 696 0.207
single organism reproductive process GO:0044702 1196 0.206
axon guidance GO:0007411 82 0.203
signal transduction GO:0007165 317 0.202
Human Fly
genitalia development GO:0048806 741 0.198
single organism transport GO:0044765 447 0.193
developmental growth GO:0048589 412 0.190
single organism signaling GO:0044700 401 0.180
Human Fly
endocytosis GO:0006897 819 0.177
protein complex subunit organization GO:0071822 280 0.171
regulation of metabolic process GO:0019222 478 0.171
Human Fly
gene expression GO:0010467 412 0.167
Human Fly
regulation of post embryonic development GO:0048580 260 0.166
transcription from rna polymerase ii promoter GO:0006366 149 0.163
Human Fly
regulation of developmental process GO:0050793 684 0.163
macromolecule localization GO:0033036 771 0.158
meiotic cell cycle GO:0051321 335 0.156
positive regulation of multicellular organismal process GO:0051240 417 0.152
multi organism behavior GO:0051705 389 0.150
neurogenesis GO:0022008 236 0.147
multi organism reproductive behavior GO:0044705 387 0.143
cell motility GO:0048870 313 0.139
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.139
skeletal muscle organ development GO:0060538 3 0.130
generation of neurons GO:0048699 235 0.126
post embryonic organ development GO:0048569 336 0.126
neuron differentiation GO:0030182 217 0.124
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.123
Human Fly
apoptotic process GO:0006915 478 0.122
cellular localization GO:0051641 360 0.122
cell projection organization GO:0030030 231 0.122
determination of adult lifespan GO:0008340 812 0.119
neuron projection development GO:0031175 187 0.119
cell projection morphogenesis GO:0048858 148 0.119
regulation of developmental growth GO:0048638 389 0.117
mitotic cell cycle process GO:1903047 194 0.116
regulation of biological quality GO:0065008 741 0.113
reproductive system development GO:0061458 850 0.112
macromolecular complex subunit organization GO:0043933 320 0.111
programmed cell death GO:0012501 500 0.110
cell surface receptor signaling pathway GO:0007166 149 0.109
Fly
multicellular organismal aging GO:0010259 812 0.107
response to chemical GO:0042221 356 0.106
cellular macromolecule biosynthetic process GO:0034645 247 0.106
Human Fly
cellular component biogenesis GO:0044085 297 0.105
regulation of gene expression GO:0010468 366 0.104
Human Fly
growth GO:0040007 562 0.104
mating behavior GO:0007617 32 0.103
sexual reproduction GO:0019953 546 0.103
vulval development GO:0040025 333 0.102
localization of cell GO:0051674 313 0.101
positive regulation of cellular metabolic process GO:0031325 178 0.101
Human
multicellular organism growth GO:0035264 385 0.100
positive regulation of cellular biosynthetic process GO:0031328 109 0.099
Human
positive regulation of developmental process GO:0051094 408 0.096
cellular component movement GO:0006928 388 0.094
cellular component assembly GO:0022607 293 0.093
regulation of multicellular organismal process GO:0051239 726 0.092
nucleic acid metabolic process GO:0090304 299 0.092
Human Fly
memory GO:0007613 3 0.091
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.090
response to organic substance GO:0010033 131 0.090
single organism localization GO:1902578 518 0.089
cellular component assembly involved in morphogenesis GO:0010927 183 0.089
lipid localization GO:0010876 573 0.087
single organism organelle organization GO:1902589 501 0.086
nucleic acid templated transcription GO:0097659 169 0.085
Human Fly
meiotic nuclear division GO:0007126 300 0.085
vesicle mediated transport GO:0016192 852 0.084
regulation of cell differentiation GO:0045595 81 0.083
negative regulation of nematode larval development GO:0061064 208 0.082
behavior GO:0007610 527 0.081
negative regulation of macromolecule metabolic process GO:0010605 229 0.078
regulation of multicellular organism growth GO:0040014 373 0.078
negative regulation of multicellular organismal process GO:0051241 236 0.078
macromolecular complex assembly GO:0065003 193 0.077
intracellular signal transduction GO:0035556 96 0.077
rna metabolic process GO:0016070 228 0.076
Human Fly
protein localization GO:0008104 205 0.075
regulation of response to stimulus GO:0048583 243 0.075
Fly
ras protein signal transduction GO:0007265 31 0.074
regulation of growth GO:0040008 409 0.073
transcription dna templated GO:0006351 168 0.072
Human Fly
actin filament based process GO:0030029 191 0.072
positive regulation of cell death GO:0010942 38 0.071
negative regulation of developmental process GO:0051093 227 0.070
positive regulation of cellular process GO:0048522 332 0.070
Human Fly
regulation of primary metabolic process GO:0080090 292 0.068
Human Fly
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.067
Human Fly
neuron development GO:0048666 199 0.067
maintenance of location GO:0051235 580 0.066
catabolic process GO:0009056 318 0.066
receptor mediated endocytosis GO:0006898 715 0.065
lipid storage GO:0019915 565 0.064
organelle assembly GO:0070925 214 0.063
regulation of signal transduction GO:0009966 135 0.063
Fly
cellular catabolic process GO:0044248 199 0.062
taxis GO:0042330 128 0.060
neuron projection guidance GO:0097485 82 0.060
anatomical structure formation involved in morphogenesis GO:0048646 250 0.060
negative regulation of metabolic process GO:0009892 240 0.059
response to wounding GO:0009611 4 0.059
cellular macromolecular complex assembly GO:0034622 184 0.058
negative regulation of bmp signaling pathway GO:0030514 1 0.057
negative regulation of cellular process GO:0048523 239 0.056
actomyosin structure organization GO:0031032 154 0.056
enzyme linked receptor protein signaling pathway GO:0007167 50 0.056
regulation of cell proliferation GO:0042127 105 0.055
positive regulation of nucleic acid templated transcription GO:1903508 102 0.054
Human
regulation of anatomical structure size GO:0090066 46 0.054
nervous system development GO:0007399 253 0.054
negative regulation of post embryonic development GO:0048581 208 0.053
regulation of cell communication GO:0010646 176 0.053
Fly
male anatomical structure morphogenesis GO:0090598 78 0.053
positive regulation of multicellular organism growth GO:0040018 352 0.052
cell morphogenesis involved in differentiation GO:0000904 112 0.052
organelle fission GO:0048285 363 0.052
regulation of cellular metabolic process GO:0031323 305 0.050
Human Fly
negative regulation of biological process GO:0048519 567 0.050
cellular protein metabolic process GO:0044267 279 0.049
establishment of localization in cell GO:0051649 318 0.049
single organism catabolic process GO:0044712 129 0.048
aromatic compound biosynthetic process GO:0019438 192 0.048
Human Fly
cell death GO:0008219 547 0.048
positive regulation of developmental growth GO:0048639 354 0.048
muscle structure development GO:0061061 191 0.048
head development GO:0060322 1 0.047
tube development GO:0035295 126 0.047
secretion by cell GO:0032940 138 0.047
regulation of localization GO:0032879 194 0.046
regulation of meiotic cell cycle GO:0051445 136 0.045
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.045
positive chemotaxis GO:0050918 3 0.045
death GO:0016265 547 0.044
molting cycle GO:0042303 281 0.043
cellular nitrogen compound biosynthetic process GO:0044271 192 0.043
Human Fly
regulation of development heterochronic GO:0040034 18 0.043
organic substance biosynthetic process GO:1901576 323 0.043
Human Fly
epithelial tube morphogenesis GO:0060562 1 0.042
cell proliferation GO:0008283 116 0.042
positive regulation of vulval development GO:0040026 52 0.042
protein metabolic process GO:0019538 422 0.041
macromolecule catabolic process GO:0009057 202 0.040
organic substance catabolic process GO:1901575 294 0.040
macromolecule biosynthetic process GO:0009059 250 0.040
Human Fly
aging GO:0007568 812 0.040
gamete generation GO:0007276 461 0.039
muscle tissue development GO:0060537 1 0.039
cellular protein complex assembly GO:0043623 178 0.039
regulation of behavior GO:0050795 97 0.039
tube morphogenesis GO:0035239 79 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.038
Human
response to external stimulus GO:0009605 289 0.038
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.037
positive regulation of rna biosynthetic process GO:1902680 102 0.037
Human
phosphorus metabolic process GO:0006793 232 0.037
cell part morphogenesis GO:0032990 152 0.036
axon development GO:0061564 163 0.036
neuromuscular junction development GO:0007528 2 0.035
response to endogenous stimulus GO:0009719 33 0.035
regulation of nervous system development GO:0051960 41 0.035
cellular macromolecule localization GO:0070727 75 0.034
cellular biosynthetic process GO:0044249 315 0.034
Human Fly
system process GO:0003008 136 0.034
dauer larval development GO:0040024 92 0.034
positive regulation of phosphorus metabolic process GO:0010562 56 0.033
nematode male tail tip morphogenesis GO:0045138 77 0.033
posttranscriptional gene silencing by rna GO:0035194 143 0.032
negative regulation of gene expression GO:0010629 217 0.032
positive regulation of neuron differentiation GO:0045666 4 0.032
dorsal ventral axon guidance GO:0033563 19 0.032
positive regulation of macromolecule metabolic process GO:0010604 149 0.031
Human
cellular response to organic substance GO:0071310 119 0.031
positive regulation of growth GO:0045927 369 0.031
regulation of cell cycle process GO:0010564 145 0.031
cell cell signaling GO:0007267 118 0.031
regulation of meiosis GO:0040020 94 0.031
regulation of locomotion GO:0040012 161 0.031
protein complex biogenesis GO:0070271 186 0.030
regulation of cellular protein metabolic process GO:0032268 75 0.030
cellular protein modification process GO:0006464 207 0.030
regulation of anatomical structure morphogenesis GO:0022603 51 0.029
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.029
Human
regulation of cytoplasmic transport GO:1903649 3 0.029
activation of jun kinase activity GO:0007257 3 0.028
regulation of bmp signaling pathway GO:0030510 3 0.028
cytoskeleton organization GO:0007010 339 0.028
cellular protein localization GO:0034613 75 0.028
regulation of gene expression epigenetic GO:0040029 163 0.028
cell type specific apoptotic process GO:0097285 4 0.028
regulation of organelle organization GO:0033043 164 0.028
cell division GO:0051301 262 0.027
membrane organization GO:0061024 135 0.027
striated muscle cell development GO:0055002 157 0.027
muscle cell development GO:0055001 158 0.027
regulation of mapk cascade GO:0043408 23 0.027
mapk cascade GO:0000165 31 0.026
sensory organ morphogenesis GO:0090596 2 0.026
mitotic nuclear division GO:0007067 89 0.026
negative regulation of cellular metabolic process GO:0031324 95 0.026
regulation of jun kinase activity GO:0043506 3 0.026
regulation of macromolecule biosynthetic process GO:0010556 189 0.026
Human Fly
regulation of cellular component size GO:0032535 40 0.026
nucleobase containing compound metabolic process GO:0006139 406 0.025
Human Fly
actin cytoskeleton organization GO:0030036 184 0.025
inductive cell migration GO:0040039 145 0.025
regulation of nucleic acid templated transcription GO:1903506 165 0.024
Human Fly
regulation of cell morphogenesis GO:0022604 40 0.024
organic cyclic compound biosynthetic process GO:1901362 195 0.024
Human Fly
kinetochore organization GO:0051383 7 0.024
axon extension GO:0048675 37 0.024
ribonucleoprotein complex assembly GO:0022618 4 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.024
Human
neuron projection morphogenesis GO:0048812 114 0.024
heterocycle biosynthetic process GO:0018130 187 0.024
Human Fly
macromolecule modification GO:0043412 218 0.024
chemotaxis GO:0006935 120 0.024
digestive system development GO:0055123 122 0.023
cell growth GO:0016049 44 0.023
regulation of ras protein signal transduction GO:0046578 41 0.023
cell projection assembly GO:0030031 35 0.023
cellular lipid metabolic process GO:0044255 40 0.023
cell substrate adhesion GO:0031589 1 0.022
positive regulation of neurogenesis GO:0050769 4 0.022
cellular response to nitrogen compound GO:1901699 24 0.022
developmental cell growth GO:0048588 39 0.022
negative regulation of nucleic acid templated transcription GO:1903507 53 0.022
regulation of neurotransmitter levels GO:0001505 36 0.022
positive regulation of transcription dna templated GO:0045893 102 0.022
Human
regulation of phosphorus metabolic process GO:0051174 81 0.022
neuron recognition GO:0008038 83 0.021
regulation of catabolic process GO:0009894 57 0.021
positive regulation of biosynthetic process GO:0009891 109 0.021
Human
regulation of reproductive process GO:2000241 66 0.021
regulation of cell projection organization GO:0031344 38 0.021
striated muscle cell differentiation GO:0051146 158 0.020
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.020
phosphate containing compound metabolic process GO:0006796 232 0.020
cognition GO:0050890 27 0.020
dosage compensation by hypoactivation of x chromosome GO:0042464 11 0.020
myofibril assembly GO:0030239 154 0.020
gene silencing by rna GO:0031047 143 0.020
myosin filament organization GO:0031033 138 0.019
regulation of neuron projection development GO:0010975 31 0.019
heterocycle catabolic process GO:0046700 119 0.019
regulation of small gtpase mediated signal transduction GO:0051056 41 0.019
positive regulation of metabolic process GO:0009893 187 0.019
Human
posttranscriptional gene silencing GO:0016441 143 0.018
synaptic transmission GO:0007268 106 0.018
tissue morphogenesis GO:0048729 65 0.018
positive regulation of mapk cascade GO:0043410 14 0.018
posttranscriptional regulation of gene expression GO:0010608 166 0.018
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.018
Human Fly
positive regulation of phosphate metabolic process GO:0045937 56 0.018
regulation of protein import into nucleus GO:0042306 3 0.018
response to acid chemical GO:0001101 4 0.018
bmp signaling pathway GO:0030509 3 0.018
positive regulation of nematode larval development GO:0061063 54 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.018
protein catabolic process GO:0030163 162 0.018
positive regulation of apoptotic process GO:0043065 17 0.017
axonogenesis GO:0007409 102 0.017
positive regulation of stem cell differentiation GO:2000738 1 0.017
mesodermal cell migration GO:0008078 9 0.017
purine nucleoside monophosphate metabolic process GO:0009126 43 0.017
neurotransmitter transport GO:0006836 32 0.017
regulation of transcription dna templated GO:0006355 164 0.017
Human Fly
positive regulation of molecular function GO:0044093 61 0.017
cellular response to chemical stimulus GO:0070887 129 0.017
protein complex assembly GO:0006461 186 0.017
regulation of multi organism process GO:0043900 69 0.017
tissue development GO:0009888 112 0.017
regulation of nucleocytoplasmic transport GO:0046822 3 0.017
cell morphogenesis GO:0000902 163 0.017
small gtpase mediated signal transduction GO:0007264 32 0.016
regulation of nuclear division GO:0051783 115 0.016
secretion GO:0046903 147 0.016
neurological system process GO:0050877 53 0.016
response to oxygen containing compound GO:1901700 44 0.016
small molecule metabolic process GO:0044281 186 0.016
synaptic growth at neuromuscular junction GO:0051124 1 0.016
regulation of biosynthetic process GO:0009889 189 0.016
Human Fly
digestive tract development GO:0048565 122 0.016
cellular amino acid metabolic process GO:0006520 15 0.016
myosin filament assembly GO:0031034 138 0.016
cellular nitrogen compound catabolic process GO:0044270 119 0.016
regulation of protein targeting GO:1903533 3 0.016
phosphorylation GO:0016310 116 0.016
gene silencing GO:0016458 143 0.016
positive regulation of cellular protein catabolic process GO:1903364 3 0.015
chromosome segregation GO:0007059 180 0.015
rna biosynthetic process GO:0032774 169 0.015
Human Fly
meiotic chromosome segregation GO:0045132 139 0.015
biosynthetic process GO:0009058 323 0.015
Human Fly
regulation of molecular function GO:0065009 89 0.015
regulation of apoptotic signaling pathway GO:2001233 1 0.015
carboxylic acid biosynthetic process GO:0046394 21 0.015
sterol transport GO:0015918 4 0.015
negative regulation of neurogenesis GO:0050768 4 0.015
mating GO:0007618 34 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.015
cellular response to stress GO:0033554 162 0.014
organic substance transport GO:0071702 113 0.014
regulation of nitrogen compound metabolic process GO:0051171 222 0.014
Human Fly
cytosolic calcium ion homeostasis GO:0051480 2 0.014
regulation of cell division GO:0051302 142 0.014
positive regulation of cell projection organization GO:0031346 4 0.014
neuron projection extension involved in neuron projection guidance GO:1902284 13 0.014
positive regulation of catabolic process GO:0009896 38 0.014
positive regulation of programmed cell death GO:0043068 27 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
positive regulation of cellular component organization GO:0051130 34 0.014
regulation of rna metabolic process GO:0051252 173 0.014
Human Fly
positive regulation of neuron projection development GO:0010976 4 0.014
regulation of cellular biosynthetic process GO:0031326 189 0.014
Human Fly
peptidyl serine modification GO:0018209 20 0.014
cellular response to endogenous stimulus GO:0071495 32 0.014
positive regulation of rna metabolic process GO:0051254 103 0.014
Human
negative regulation of signaling GO:0023057 61 0.013
regulation of cellular component movement GO:0051270 62 0.013
protein phosphorylation GO:0006468 85 0.013
regulation of cell development GO:0060284 49 0.013
positive regulation of protein modification process GO:0031401 29 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
regeneration GO:0031099 4 0.013
regulation of cell cycle GO:0051726 194 0.013
regulation of cell motility GO:2000145 57 0.013
nucleoside metabolic process GO:0009116 99 0.013
striated muscle myosin thick filament assembly GO:0071688 138 0.013
regulation of oviposition GO:0046662 43 0.013
cytokinetic cell separation GO:0000920 5 0.013
positive regulation of stress activated mapk cascade GO:0032874 3 0.013
axonal defasciculation GO:0007414 1 0.013
positive regulation of protein metabolic process GO:0051247 45 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
organ morphogenesis GO:0009887 67 0.013
Fly
response to organonitrogen compound GO:0010243 15 0.012
rna interference GO:0016246 137 0.012
positive regulation of proteasomal protein catabolic process GO:1901800 1 0.012
synaptic vesicle recycling GO:0036465 3 0.012
organonitrogen compound metabolic process GO:1901564 151 0.012
neuron projection extension GO:1990138 37 0.012
muscle cell differentiation GO:0042692 171 0.012
regulation of canonical wnt signaling pathway GO:0060828 1 0.012
regulation of phosphate metabolic process GO:0019220 81 0.012
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.012
cellular response to growth factor stimulus GO:0071363 18 0.012
positive regulation of gene expression GO:0010628 112 0.011
Human
negative regulation of rna metabolic process GO:0051253 53 0.011
cell recognition GO:0008037 85 0.011
p38mapk cascade GO:0038066 2 0.011
ribonucleoside catabolic process GO:0042454 77 0.011
single organism intracellular transport GO:1902582 70 0.011
protein transport GO:0015031 45 0.011
cuticle development GO:0042335 100 0.011
positive regulation of cell migration GO:0030335 3 0.011
neuron apoptotic process GO:0051402 4 0.011
positive regulation of signaling GO:0023056 66 0.011
Fly
regulation of programmed cell death GO:0043067 50 0.011
pigmentation GO:0043473 2 0.011
regulation of protein localization GO:0032880 50 0.011
cellular amine metabolic process GO:0044106 15 0.011
positive regulation of jun kinase activity GO:0043507 3 0.011
response to nitrogen compound GO:1901698 25 0.011
synapse organization GO:0050808 24 0.011
purine ribonucleoside catabolic process GO:0046130 75 0.011
regulation of protein stability GO:0031647 3 0.011
organophosphate catabolic process GO:0046434 81 0.010
single organism carbohydrate metabolic process GO:0044723 29 0.010
nucleobase containing small molecule metabolic process GO:0055086 115 0.010
male sex differentiation GO:0046661 86 0.010
peptidyl tyrosine modification GO:0018212 3 0.010
protein oligomerization GO:0051259 4 0.010
positive regulation of catalytic activity GO:0043085 59 0.010
organophosphate metabolic process GO:0019637 125 0.010
positive regulation of cell communication GO:0010647 69 0.010
Fly

let-19 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.019
epilepsy syndrome DOID:1826 0 0.012
central nervous system disease DOID:331 0 0.012
brain disease DOID:936 0 0.012
electroclinical syndrome DOID:0050701 0 0.012
neonatal period electroclinical syndrome DOID:0050702 0 0.012