Caenorhabditis elegans

34 known processes

rpb-2 (CELE_C26E6.4)

Protein RPB-2

rpb-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.937
embryo development ending in birth or egg hatching GO:0009792 2992 0.886
post embryonic development GO:0009791 2152 0.842
reproductive system development GO:0061458 850 0.821
gamete generation GO:0007276 461 0.808
germ cell development GO:0007281 351 0.723
sexual reproduction GO:0019953 546 0.714
development of primary sexual characteristics GO:0045137 840 0.633
genitalia development GO:0048806 741 0.627
organelle organization GO:0006996 783 0.622
single organism reproductive process GO:0044702 1196 0.588
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.565
locomotion GO:0040011 1634 0.543
cell cycle process GO:0022402 482 0.525
multicellular organism reproduction GO:0032504 819 0.511
establishment of localization GO:0051234 1171 0.477
developmental process involved in reproduction GO:0003006 1165 0.451
apoptotic process GO:0006915 478 0.447
meiotic cell cycle process GO:1903046 170 0.444
organ development GO:0048513 1102 0.442
single organism organelle organization GO:1902589 501 0.426
reproductive structure development GO:0048608 850 0.423
regulation of meiotic cell cycle GO:0051445 136 0.411
meiotic nuclear division GO:0007126 300 0.410
gonad development GO:0008406 840 0.401
cell migration GO:0016477 306 0.395
cell cycle GO:0007049 526 0.374
multi organism reproductive process GO:0044703 867 0.368
regulation of meiosis GO:0040020 94 0.352
localization of cell GO:0051674 313 0.339
regulation of nuclear division GO:0051783 115 0.319
hermaphrodite genitalia development GO:0040035 734 0.313
oogenesis GO:0048477 229 0.307
organelle fission GO:0048285 363 0.302
cellular component biogenesis GO:0044085 297 0.292
meiotic cell cycle GO:0051321 335 0.290
cell motility GO:0048870 313 0.289
female gamete generation GO:0007292 254 0.288
cellular component assembly GO:0022607 293 0.280
multicellular organismal reproductive process GO:0048609 815 0.269
rrna metabolic process GO:0016072 3 0.265
regulation of cellular component organization GO:0051128 248 0.262
macromolecule biosynthetic process GO:0009059 250 0.262
Human
transport GO:0006810 1093 0.262
regulation of organelle organization GO:0033043 164 0.240
sex differentiation GO:0007548 909 0.240
gene expression GO:0010467 412 0.227
Human
regulation of cell division GO:0051302 142 0.201
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.199
macromolecular complex subunit organization GO:0043933 320 0.198
protein complex subunit organization GO:0071822 280 0.194
endocytosis GO:0006897 819 0.177
vesicle mediated transport GO:0016192 852 0.176
inductive cell migration GO:0040039 145 0.173
molting cycle GO:0042303 281 0.166
single fertilization GO:0007338 61 0.162
establishment of localization in cell GO:0051649 318 0.160
nucleic acid metabolic process GO:0090304 299 0.156
Human
regulation of macromolecule metabolic process GO:0060255 421 0.155
death GO:0016265 547 0.153
cellular component movement GO:0006928 388 0.151
macromolecular complex assembly GO:0065003 193 0.145
establishment of organelle localization GO:0051656 123 0.144
neurogenesis GO:0022008 236 0.140
cellular macromolecule biosynthetic process GO:0034645 247 0.133
Human
cell division GO:0051301 262 0.131
rna biosynthetic process GO:0032774 169 0.130
Human
multicellular organismal aging GO:0010259 812 0.129
aging GO:0007568 812 0.125
neuron projection development GO:0031175 187 0.112
aromatic compound biosynthetic process GO:0019438 192 0.111
Human
programmed cell death GO:0012501 500 0.111
regulation of biological quality GO:0065008 741 0.109
cell development GO:0048468 696 0.109
nucleic acid templated transcription GO:0097659 169 0.109
Human
cellular localization GO:0051641 360 0.108
translational initiation GO:0006413 2 0.104
fertilization GO:0009566 63 0.103
body morphogenesis GO:0010171 620 0.102
neuron projection morphogenesis GO:0048812 114 0.101
protein metabolic process GO:0019538 422 0.100
regulation of cell cycle process GO:0010564 145 0.093
receptor mediated endocytosis GO:0006898 715 0.093
nucleobase containing compound metabolic process GO:0006139 406 0.091
Human
transcription dna templated GO:0006351 168 0.084
Human
vulval development GO:0040025 333 0.082
response to abiotic stimulus GO:0009628 152 0.082
mitotic cell cycle process GO:1903047 194 0.080
nervous system development GO:0007399 253 0.079
regulation of developmental process GO:0050793 684 0.079
protein complex assembly GO:0006461 186 0.079
macromolecule localization GO:0033036 771 0.077
growth GO:0040007 562 0.076
positive regulation of nucleic acid templated transcription GO:1903508 102 0.075
regulation of cellular metabolic process GO:0031323 305 0.074
positive regulation of multicellular organismal process GO:0051240 417 0.073
single organism transport GO:0044765 447 0.073
developmental growth GO:0048589 412 0.073
cell death GO:0008219 547 0.071
determination of adult lifespan GO:0008340 812 0.068
organelle localization GO:0051640 127 0.067
cellular biosynthetic process GO:0044249 315 0.066
Human
single organism localization GO:1902578 518 0.066
macromolecule modification GO:0043412 218 0.064
cellular protein metabolic process GO:0044267 279 0.064
negative regulation of gene expression GO:0010629 217 0.063
rrna processing GO:0006364 3 0.061
negative regulation of chromosome segregation GO:0051985 4 0.057
organic substance biosynthetic process GO:1901576 323 0.056
Human
catabolic process GO:0009056 318 0.056
nucleobase containing compound biosynthetic process GO:0034654 184 0.056
Human
cell part morphogenesis GO:0032990 152 0.055
cellular macromolecular complex assembly GO:0034622 184 0.055
mrna metabolic process GO:0016071 31 0.054
positive regulation of multicellular organism growth GO:0040018 352 0.053
regulation of nitrogen compound metabolic process GO:0051171 222 0.052
endonucleolytic cleavage involved in rrna processing GO:0000478 1 0.052
regulation of macromolecule biosynthetic process GO:0010556 189 0.052
lipid storage GO:0019915 565 0.051
regulation of cellular biosynthetic process GO:0031326 189 0.051
maintenance of location GO:0051235 580 0.049
gene silencing GO:0016458 143 0.049
regulation of cell cycle GO:0051726 194 0.049
cytoskeleton organization GO:0007010 339 0.049
mitotic spindle organization GO:0007052 81 0.049
phosphate containing compound metabolic process GO:0006796 232 0.049
positive regulation of cellular process GO:0048522 332 0.048
establishment of spindle localization GO:0051293 51 0.048
regulation of gene expression GO:0010468 366 0.047
posttranscriptional regulation of gene expression GO:0010608 166 0.047
microtubule based process GO:0007017 182 0.047
chromatin assembly or disassembly GO:0006333 1 0.046
regulation of primary metabolic process GO:0080090 292 0.046
regulation of multicellular organismal process GO:0051239 726 0.045
lipid localization GO:0010876 573 0.045
cellular component morphogenesis GO:0032989 318 0.044
positive regulation of macromolecule metabolic process GO:0010604 149 0.044
cellular protein complex assembly GO:0043623 178 0.044
axon development GO:0061564 163 0.044
positive regulation of transcription dna templated GO:0045893 102 0.043
embryonic morphogenesis GO:0048598 152 0.043
regulation of multicellular organismal development GO:2000026 317 0.043
negative regulation of nucleic acid templated transcription GO:1903507 53 0.043
head development GO:0060322 1 0.042
protein complex biogenesis GO:0070271 186 0.042
regulation of cell proliferation GO:0042127 105 0.042
macromolecule catabolic process GO:0009057 202 0.042
regulation of cell differentiation GO:0045595 81 0.041
establishment or maintenance of cell polarity GO:0007163 63 0.041
gene silencing by rna GO:0031047 143 0.041
spindle organization GO:0007051 92 0.041
negative regulation of vulval development GO:0040027 206 0.040
regulation of rna biosynthetic process GO:2001141 165 0.040
positive regulation of cellular metabolic process GO:0031325 178 0.040
dna templated transcription termination GO:0006353 1 0.040
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.040
negative regulation of macromolecule metabolic process GO:0010605 229 0.040
cell proliferation GO:0008283 116 0.040
ribosome biogenesis GO:0042254 4 0.039
negative regulation of cellular process GO:0048523 239 0.039
chromatin assembly GO:0031497 1 0.039
regulation of vulval development GO:0040028 248 0.039
rna metabolic process GO:0016070 228 0.038
Human
behavior GO:0007610 527 0.038
establishment of mitotic spindle localization GO:0040001 41 0.038
positive regulation of chromosome organization GO:2001252 2 0.037
response to heat GO:0009408 50 0.037
generation of neurons GO:0048699 235 0.037
negative regulation of developmental process GO:0051093 227 0.036
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.035
meiotic chromosome segregation GO:0045132 139 0.035
regulation of developmental growth GO:0048638 389 0.035
dna templated transcription elongation GO:0006354 1 0.034
muscle structure development GO:0061061 191 0.034
regulation of gene expression epigenetic GO:0040029 163 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.033
regulation of nucleic acid templated transcription GO:1903506 165 0.032
pronuclear migration GO:0035046 51 0.032
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.032
regulation of metabolic process GO:0019222 478 0.032
negative regulation of biosynthetic process GO:0009890 65 0.032
single organism signaling GO:0044700 401 0.032
spindle localization GO:0051653 51 0.032
axonogenesis GO:0007409 102 0.031
purine containing compound metabolic process GO:0072521 95 0.031
positive regulation of developmental process GO:0051094 408 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.031
biosynthetic process GO:0009058 323 0.031
Human
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.030
positive regulation of cellular biosynthetic process GO:0031328 109 0.030
regulation of rna metabolic process GO:0051252 173 0.030
neuron differentiation GO:0030182 217 0.030
mitotic sister chromatid segregation GO:0000070 38 0.029
negative regulation of gene expression epigenetic GO:0045814 2 0.029
positive regulation of nematode larval development GO:0061063 54 0.029
cell projection morphogenesis GO:0048858 148 0.028
signaling GO:0023052 401 0.028
positive regulation of metabolic process GO:0009893 187 0.028
chromatin remodeling GO:0006338 2 0.028
regulation of biosynthetic process GO:0009889 189 0.028
neuromuscular junction development GO:0007528 2 0.027
cellular catabolic process GO:0044248 199 0.027
regulation of neuron projection development GO:0010975 31 0.027
protein dna complex assembly GO:0065004 7 0.027
negative regulation of metabolic process GO:0009892 240 0.027
cleavage involved in rrna processing GO:0000469 2 0.026
multicellular organismal reproductive behavior GO:0033057 384 0.026
specification of axis polarity GO:0065001 13 0.025
reproductive behavior GO:0019098 387 0.025
dna metabolic process GO:0006259 74 0.025
cellular response to stress GO:0033554 162 0.025
oviposition GO:0018991 364 0.025
regulation of mitosis GO:0007088 18 0.025
regulation of growth GO:0040008 409 0.024
regulation of nematode larval development GO:0061062 260 0.024
regulation of anatomical structure size GO:0090066 46 0.024
phosphorus metabolic process GO:0006793 232 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.023
dna conformation change GO:0071103 11 0.023
organic substance catabolic process GO:1901575 294 0.023
oocyte development GO:0048599 44 0.023
negative regulation of rna biosynthetic process GO:1902679 53 0.023
regulation of cell motility GO:2000145 57 0.022
multi organism reproductive behavior GO:0044705 387 0.022
heterocycle catabolic process GO:0046700 119 0.022
regulation of post embryonic development GO:0048580 260 0.022
positive regulation of nucleoside metabolic process GO:0045979 28 0.022
purine nucleoside metabolic process GO:0042278 92 0.022
tube development GO:0035295 126 0.022
purine nucleoside triphosphate metabolic process GO:0009144 87 0.021
covalent chromatin modification GO:0016569 30 0.021
cell cycle phase transition GO:0044770 19 0.021
cell morphogenesis involved in differentiation GO:0000904 112 0.021
positive regulation of vulval development GO:0040026 52 0.021
positive regulation of developmental growth GO:0048639 354 0.021
multi multicellular organism process GO:0044706 390 0.021
ribose phosphate metabolic process GO:0019693 99 0.021
rna processing GO:0006396 34 0.021
regulation of multicellular organism growth GO:0040014 373 0.020
cellular nitrogen compound biosynthetic process GO:0044271 192 0.020
Human
organic cyclic compound biosynthetic process GO:1901362 195 0.020
Human
regulation of cellular component biogenesis GO:0044087 26 0.020
intracellular transport GO:0046907 77 0.020
posttranscriptional gene silencing GO:0016441 143 0.020
protein modification process GO:0036211 207 0.020
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.019
negative regulation of nematode larval development GO:0061064 208 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.019
protein catabolic process GO:0030163 162 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.019
myosin filament organization GO:0031033 138 0.019
mitotic sister chromatid separation GO:0051306 13 0.019
translation GO:0006412 37 0.019
tissue development GO:0009888 112 0.019
posttranscriptional gene silencing by rna GO:0035194 143 0.018
protein polymerization GO:0051258 26 0.018
embryonic body morphogenesis GO:0010172 49 0.018
negative regulation of cellular metabolic process GO:0031324 95 0.018
cellular protein modification process GO:0006464 207 0.018
rna interference GO:0016246 137 0.018
ncrna metabolic process GO:0034660 14 0.018
digestive tract development GO:0048565 122 0.017
response to external stimulus GO:0009605 289 0.017
regulation of transcription dna templated GO:0006355 164 0.017
actin filament based process GO:0030029 191 0.017
taxis GO:0042330 128 0.017
post embryonic organ development GO:0048569 336 0.017
neuron development GO:0048666 199 0.017
negative regulation of post embryonic development GO:0048581 208 0.017
multicellular organism growth GO:0035264 385 0.017
nucleoside phosphate metabolic process GO:0006753 108 0.017
response to temperature stimulus GO:0009266 66 0.017
secretion GO:0046903 147 0.016
actin cytoskeleton organization GO:0030036 184 0.016
cell type specific apoptotic process GO:0097285 4 0.016
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 4 0.016
negative regulation of biological process GO:0048519 567 0.016
negative regulation of transcription dna templated GO:0045892 53 0.016
dna geometric change GO:0032392 3 0.016
positive regulation of gene expression GO:0010628 112 0.016
muscle organ morphogenesis GO:0048644 4 0.016
signal transduction GO:0007165 317 0.016
regulation of nervous system development GO:0051960 41 0.016
regulation of mitotic cell cycle GO:0007346 76 0.015
secretion by cell GO:0032940 138 0.015
regulation of protein metabolic process GO:0051246 81 0.015
ubiquitin dependent protein catabolic process GO:0006511 32 0.015
multi organism behavior GO:0051705 389 0.015
glycosyl compound catabolic process GO:1901658 79 0.015
cellular component assembly involved in morphogenesis GO:0010927 183 0.015
chromosome organization GO:0051276 104 0.015
single organism behavior GO:0044708 83 0.015
cell morphogenesis GO:0000902 163 0.015
trna processing GO:0008033 3 0.015
myosin filament assembly GO:0031034 138 0.015
digestive system development GO:0055123 122 0.015
regulation of protein targeting GO:1903533 3 0.014
meiosis i GO:0007127 19 0.014
organic substance transport GO:0071702 113 0.014
positive regulation of rna biosynthetic process GO:1902680 102 0.014
modification dependent macromolecule catabolic process GO:0043632 32 0.014
negative regulation of rna metabolic process GO:0051253 53 0.014
negative regulation of cellular catabolic process GO:0031330 9 0.014
cell projection organization GO:0030030 231 0.014
g1 s transition of mitotic cell cycle GO:0000082 2 0.014
regulation of cellular protein metabolic process GO:0032268 75 0.013
rna localization GO:0006403 3 0.013
protein modification by small protein conjugation or removal GO:0070647 40 0.013
negative regulation of cellular protein metabolic process GO:0032269 27 0.013
ribonucleoprotein complex assembly GO:0022618 4 0.013
negative regulation of cellular protein catabolic process GO:1903363 4 0.013
nucleobase containing compound catabolic process GO:0034655 114 0.013
striated muscle myosin thick filament assembly GO:0071688 138 0.013
response to wounding GO:0009611 4 0.013
regulation of anatomical structure morphogenesis GO:0022603 51 0.013
negative regulation of multicellular organismal process GO:0051241 236 0.012
regulation of cell projection organization GO:0031344 38 0.012
regulation of cell migration GO:0030334 55 0.012
regulation of cell projection assembly GO:0060491 3 0.012
positive regulation of cell cycle GO:0045787 55 0.012
mrna splice site selection GO:0006376 1 0.012
sister chromatid segregation GO:0000819 46 0.012
regulation of cell development GO:0060284 49 0.012
single organism catabolic process GO:0044712 129 0.012
nuclear migration GO:0007097 54 0.012
negative regulation of cellular biosynthetic process GO:0031327 65 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.012
regeneration GO:0031099 4 0.012
heterocycle biosynthetic process GO:0018130 187 0.012
Human
phosphorylation GO:0016310 116 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.011
establishment of spindle orientation GO:0051294 34 0.011
dauer larval development GO:0040024 92 0.011
positive regulation of rna metabolic process GO:0051254 103 0.011
feminization of hermaphroditic germ line GO:0040022 34 0.011
positive regulation of growth GO:0045927 369 0.011
neurological system process GO:0050877 53 0.011
negative regulation of protein metabolic process GO:0051248 27 0.011
ribonucleotide metabolic process GO:0009259 99 0.011
cytokinesis GO:0000910 80 0.011
sensory organ morphogenesis GO:0090596 2 0.011
chromatin organization GO:0006325 32 0.011
negative regulation of cellular component organization GO:0051129 33 0.011
myofibril assembly GO:0030239 154 0.011
regulation of nucleocytoplasmic transport GO:0046822 3 0.011
protein deubiquitination GO:0016579 2 0.011
cell cycle g1 s phase transition GO:0044843 2 0.011
regulation of programmed cell death GO:0043067 50 0.011
ribonucleoside triphosphate metabolic process GO:0009199 87 0.011
negative regulation of proteasomal protein catabolic process GO:1901799 4 0.011
atp metabolic process GO:0046034 42 0.011
regulation of molecular function GO:0065009 89 0.011
internal peptidyl lysine acetylation GO:0018393 3 0.011
regulation of neurogenesis GO:0050767 40 0.011
modification dependent protein catabolic process GO:0019941 32 0.010
organ morphogenesis GO:0009887 67 0.010
protein localization to organelle GO:0033365 37 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.010
organonitrogen compound metabolic process GO:1901564 151 0.010
adult behavior GO:0030534 3 0.010
response to external biotic stimulus GO:0043207 101 0.010
regulation of locomotion GO:0040012 161 0.010
cellular response to abiotic stimulus GO:0071214 4 0.010
regulation of cellular component size GO:0032535 40 0.010

rpb-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
neuromuscular disease DOID:440 0 0.017
charcot marie tooth disease type 2 DOID:0050539 0 0.017
charcot marie tooth disease DOID:10595 0 0.017
nervous system disease DOID:863 0 0.017
neuropathy DOID:870 0 0.017
disease of metabolism DOID:0014667 0 0.011