Caenorhabditis elegans

32 known processes

vab-2 (CELE_Y37E11AR.6)

Protein VAB-2

vab-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.467
embryo development ending in birth or egg hatching GO:0009792 2992 0.393
locomotion GO:0040011 1634 0.307
Human Zebrafish Mouse Worm
organelle organization GO:0006996 783 0.240
Mouse
post embryonic development GO:0009791 2152 0.230
multi organism reproductive process GO:0044703 867 0.180
Worm
multicellular organism reproduction GO:0032504 819 0.164
Worm
regulation of cellular biosynthetic process GO:0031326 189 0.152
Mouse
organ development GO:0048513 1102 0.137
organic cyclic compound biosynthetic process GO:1901362 195 0.132
Mouse
gene expression GO:0010467 412 0.130
Mouse
cellular macromolecule biosynthetic process GO:0034645 247 0.113
Mouse
establishment of localization GO:0051234 1171 0.107
Mouse
single organism organelle organization GO:1902589 501 0.105
Mouse
nucleobase containing compound metabolic process GO:0006139 406 0.104
Mouse
regulation of biological quality GO:0065008 741 0.104
Mouse
phosphate containing compound metabolic process GO:0006796 232 0.103
Mouse
reproductive structure development GO:0048608 850 0.102
heterocycle biosynthetic process GO:0018130 187 0.100
Mouse
phosphorus metabolic process GO:0006793 232 0.097
Mouse
organic substance biosynthetic process GO:1901576 323 0.095
Mouse
transcription from rna polymerase ii promoter GO:0006366 149 0.093
Mouse
aromatic compound biosynthetic process GO:0019438 192 0.090
Mouse
regulation of multicellular organismal process GO:0051239 726 0.089
Mouse Worm
development of primary sexual characteristics GO:0045137 840 0.088
nucleobase containing compound biosynthetic process GO:0034654 184 0.088
Mouse
regulation of rna biosynthetic process GO:2001141 165 0.084
Mouse
negative regulation of biological process GO:0048519 567 0.081
Mouse Worm
endocytosis GO:0006897 819 0.081
cell motility GO:0048870 313 0.079
Human Zebrafish Mouse Worm
cellular biosynthetic process GO:0044249 315 0.079
Mouse
transport GO:0006810 1093 0.078
Mouse
macromolecular complex subunit organization GO:0043933 320 0.076
macromolecule localization GO:0033036 771 0.073
transcription dna templated GO:0006351 168 0.073
Mouse
programmed cell death GO:0012501 500 0.073
regulation of primary metabolic process GO:0080090 292 0.071
Mouse
aging GO:0007568 812 0.070
cell migration GO:0016477 306 0.070
Human Zebrafish Mouse Worm
multicellular organismal aging GO:0010259 812 0.069
determination of adult lifespan GO:0008340 812 0.069
cell cycle GO:0007049 526 0.069
macromolecule biosynthetic process GO:0009059 250 0.068
Mouse
rna biosynthetic process GO:0032774 169 0.067
Mouse
cytoskeleton organization GO:0007010 339 0.067
Mouse
cellular component movement GO:0006928 388 0.066
Human Zebrafish Mouse Worm
cell death GO:0008219 547 0.066
apoptotic process GO:0006915 478 0.066
regulation of gene expression GO:0010468 366 0.065
Mouse
lipid localization GO:0010876 573 0.065
cell cycle process GO:0022402 482 0.064
growth GO:0040007 562 0.062
regulation of biosynthetic process GO:0009889 189 0.062
Mouse
macromolecule modification GO:0043412 218 0.062
Mouse
gonad development GO:0008406 840 0.062
lipid storage GO:0019915 565 0.061
maintenance of location GO:0051235 580 0.061
regulation of metabolic process GO:0019222 478 0.060
Mouse
hermaphrodite genitalia development GO:0040035 734 0.060
signal transduction GO:0007165 317 0.060
regulation of macromolecule metabolic process GO:0060255 421 0.059
Mouse
protein metabolic process GO:0019538 422 0.059
Mouse
nucleic acid templated transcription GO:0097659 169 0.058
Mouse
female gamete generation GO:0007292 254 0.058
Worm
regulation of nucleic acid templated transcription GO:1903506 165 0.058
Mouse
positive regulation of catalytic activity GO:0043085 59 0.057
Mouse
nucleic acid metabolic process GO:0090304 299 0.056
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.055
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 192 0.055
Mouse
reproductive system development GO:0061458 850 0.054
receptor mediated endocytosis GO:0006898 715 0.054
cellular response to stress GO:0033554 162 0.054
sex differentiation GO:0007548 909 0.054
Worm
death GO:0016265 547 0.053
positive regulation of cellular process GO:0048522 332 0.053
Mouse
positive regulation of cellular metabolic process GO:0031325 178 0.053
Mouse
regulation of cellular metabolic process GO:0031323 305 0.053
Mouse
gamete generation GO:0007276 461 0.053
Worm
defense response GO:0006952 296 0.052
cellular protein metabolic process GO:0044267 279 0.052
Mouse
negative regulation of gene expression GO:0010629 217 0.051
Mouse
post embryonic organ development GO:0048569 336 0.051
regulation of rna metabolic process GO:0051252 173 0.051
Mouse
phosphorylation GO:0016310 116 0.050
Mouse
vesicle mediated transport GO:0016192 852 0.050
developmental process involved in reproduction GO:0003006 1165 0.050
Worm
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.049
regulation of developmental process GO:0050793 684 0.047
Mouse
single organism localization GO:1902578 518 0.047
Mouse
multi organism behavior GO:0051705 389 0.046
positive regulation of multicellular organismal process GO:0051240 417 0.045
Mouse
single organism reproductive process GO:0044702 1196 0.045
Worm
skeletal muscle organ development GO:0060538 3 0.044
positive regulation of gene expression GO:0010628 112 0.043
positive regulation of developmental process GO:0051094 408 0.042
Mouse
multicellular organismal reproductive process GO:0048609 815 0.042
Worm
localization of cell GO:0051674 313 0.042
Human Zebrafish Mouse Worm
vulval development GO:0040025 333 0.042
positive regulation of biosynthetic process GO:0009891 109 0.042
cell development GO:0048468 696 0.042
Zebrafish Mouse
genitalia development GO:0048806 741 0.041
biosynthetic process GO:0009058 323 0.039
Mouse
actin cytoskeleton organization GO:0030036 184 0.038
Mouse
catabolic process GO:0009056 318 0.038
Mouse
germ cell development GO:0007281 351 0.038
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.038
Mouse
regulation of multicellular organism growth GO:0040014 373 0.038
regulation of developmental growth GO:0048638 389 0.037
protein complex subunit organization GO:0071822 280 0.037
regulation of catalytic activity GO:0050790 78 0.037
Mouse
regulation of molecular function GO:0065009 89 0.037
Mouse
regulation of nitrogen compound metabolic process GO:0051171 222 0.037
Mouse
signaling GO:0023052 401 0.036
regulation of nematode larval development GO:0061062 260 0.036
organic substance catabolic process GO:1901575 294 0.036
Mouse
regulation of cellular component organization GO:0051128 248 0.036
Mouse
regulation of multicellular organismal development GO:2000026 317 0.036
Mouse
negative regulation of cellular process GO:0048523 239 0.036
Mouse
positive regulation of macromolecule metabolic process GO:0010604 149 0.035
Mouse
mitotic cell cycle process GO:1903047 194 0.035
regulation of cell cycle process GO:0010564 145 0.035
canonical wnt signaling pathway GO:0060070 3 0.035
muscle structure development GO:0061061 191 0.035
Mouse
behavior GO:0007610 527 0.035
Human Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.034
digestive tract morphogenesis GO:0048546 76 0.034
Worm
organelle fission GO:0048285 363 0.034
actin filament based process GO:0030029 191 0.034
Mouse
regulation of post embryonic development GO:0048580 260 0.033
organelle localization GO:0051640 127 0.033
regulation of organelle organization GO:0033043 164 0.033
Mouse
innate immune response GO:0045087 190 0.032
muscle tissue development GO:0060537 1 0.032
Mouse
regulation of vulval development GO:0040028 248 0.032
spindle organization GO:0007051 92 0.032
digestive tract development GO:0048565 122 0.032
Worm
synaptic target recognition GO:0008039 3 0.032
Zebrafish
protein phosphorylation GO:0006468 85 0.032
Mouse
oviposition GO:0018991 364 0.032
negative regulation of macromolecule metabolic process GO:0010605 229 0.032
Mouse
single organism transport GO:0044765 447 0.031
Mouse
tube morphogenesis GO:0035239 79 0.031
Worm
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.031
body morphogenesis GO:0010171 620 0.031
developmental growth GO:0048589 412 0.031
sexual reproduction GO:0019953 546 0.030
Worm
positive regulation of transcription dna templated GO:0045893 102 0.030
regulation of growth GO:0040008 409 0.030
intracellular signal transduction GO:0035556 96 0.029
Mouse
establishment of localization in cell GO:0051649 318 0.029
Mouse
multicellular organism growth GO:0035264 385 0.029
positive regulation of phosphorus metabolic process GO:0010562 56 0.028
Mouse
rna metabolic process GO:0016070 228 0.028
Mouse
response to chemical GO:0042221 356 0.027
Human Mouse
positive regulation of growth GO:0045927 369 0.027
establishment of organelle localization GO:0051656 123 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.027
Mouse
positive regulation of developmental growth GO:0048639 354 0.027
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.026
Mouse
protein localization GO:0008104 205 0.026
response to external stimulus GO:0009605 289 0.026
Human Mouse
regulation of phosphorus metabolic process GO:0051174 81 0.026
Mouse
positive regulation of metabolic process GO:0009893 187 0.026
Mouse
multi organism reproductive behavior GO:0044705 387 0.025
organonitrogen compound catabolic process GO:1901565 90 0.025
Mouse
response to wounding GO:0009611 4 0.025
positive regulation of phosphate metabolic process GO:0045937 56 0.025
Mouse
cellular component biogenesis GO:0044085 297 0.025
regulation of transport GO:0051049 91 0.025
Mouse
multicellular organismal reproductive behavior GO:0033057 384 0.025
phagocytosis GO:0006909 115 0.025
cellular nitrogen compound catabolic process GO:0044270 119 0.024
Mouse
head development GO:0060322 1 0.024
Zebrafish
positive regulation of multicellular organism growth GO:0040018 352 0.024
regulation of cell cycle GO:0051726 194 0.024
asymmetric protein localization GO:0008105 35 0.024
nucleoside triphosphate metabolic process GO:0009141 87 0.024
Mouse
protein complex biogenesis GO:0070271 186 0.024
regulation of transcription dna templated GO:0006355 164 0.024
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 87 0.023
Mouse
cell surface receptor signaling pathway GO:0007166 149 0.023
immune response GO:0006955 192 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.023
regulation of macromolecule biosynthetic process GO:0010556 189 0.023
Mouse
male sex differentiation GO:0046661 86 0.023
Worm
protein modification process GO:0036211 207 0.023
Mouse
regulation of localization GO:0032879 194 0.023
Mouse
epithelial tube morphogenesis GO:0060562 1 0.022
multi multicellular organism process GO:0044706 390 0.022
inductive cell migration GO:0040039 145 0.022
positive regulation of nucleic acid templated transcription GO:1903508 102 0.022
cellular component assembly GO:0022607 293 0.022
digestive system development GO:0055123 122 0.022
Worm
tube development GO:0035295 126 0.022
Worm
negative regulation of rna metabolic process GO:0051253 53 0.022
Mouse
cellular protein modification process GO:0006464 207 0.021
Mouse
macromolecular complex assembly GO:0065003 193 0.021
cellular protein complex assembly GO:0043623 178 0.021
cuticle development GO:0042335 100 0.021
apoptotic cell clearance GO:0043277 111 0.021
nucleobase containing compound catabolic process GO:0034655 114 0.021
Mouse
cell fate commitment GO:0045165 139 0.021
epithelium development GO:0060429 68 0.021
cellular localization GO:0051641 360 0.021
Mouse
negative regulation of transcription dna templated GO:0045892 53 0.021
Mouse
protein complex assembly GO:0006461 186 0.021
response to organic substance GO:0010033 131 0.021
Mouse
negative regulation of metabolic process GO:0009892 240 0.021
Mouse
regulation of signaling GO:0023051 172 0.021
Mouse
muscle cell development GO:0055001 158 0.021
single organism catabolic process GO:0044712 129 0.020
Mouse
purine nucleoside metabolic process GO:0042278 92 0.020
Mouse
cellular macromolecular complex assembly GO:0034622 184 0.020
sensory organ morphogenesis GO:0090596 2 0.020
wnt signaling pathway GO:0016055 27 0.020
positive regulation of cellular biosynthetic process GO:0031328 109 0.019
establishment of spindle localization GO:0051293 51 0.019
aromatic compound catabolic process GO:0019439 116 0.019
Mouse
carbohydrate derivative catabolic process GO:1901136 82 0.019
Mouse
oogenesis GO:0048477 229 0.019
meiotic cell cycle GO:0051321 335 0.019
embryonic morphogenesis GO:0048598 152 0.019
Mouse Worm
striated muscle cell development GO:0055002 157 0.019
negative regulation of biosynthetic process GO:0009890 65 0.019
Mouse
collagen and cuticulin based cuticle development GO:0040002 99 0.018
positive regulation of rna metabolic process GO:0051254 103 0.018
mitotic spindle organization GO:0007052 81 0.018
regulation of cell fate specification GO:0042659 22 0.018
carbohydrate derivative metabolic process GO:1901135 141 0.018
Mouse
cell division GO:0051301 262 0.018
adult behavior GO:0030534 3 0.018
Mouse
nucleoside metabolic process GO:0009116 99 0.018
Mouse
organophosphate metabolic process GO:0019637 125 0.018
Mouse
small molecule metabolic process GO:0044281 186 0.018
Mouse
regulation of cell communication GO:0010646 176 0.018
Mouse
regulation of cell motility GO:2000145 57 0.018
Mouse
cellular catabolic process GO:0044248 199 0.018
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 250 0.018
Human Zebrafish Mouse
nucleoside phosphate metabolic process GO:0006753 108 0.017
Mouse
spindle localization GO:0051653 51 0.017
regulation of protein metabolic process GO:0051246 81 0.017
Mouse
regulation of cell fate commitment GO:0010453 22 0.017
negative regulation of nematode larval development GO:0061064 208 0.017
ribonucleotide metabolic process GO:0009259 99 0.017
Mouse
macromolecule catabolic process GO:0009057 202 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.017
Mouse
regulation of cell division GO:0051302 142 0.017
reproductive behavior GO:0019098 387 0.017
regulation of cellular protein metabolic process GO:0032268 75 0.017
Mouse
negative regulation of post embryonic development GO:0048581 208 0.016
organonitrogen compound metabolic process GO:1901564 151 0.016
Mouse
cell cell signaling GO:0007267 118 0.016
Mouse
positive regulation of cell communication GO:0010647 69 0.016
Mouse
mapk cascade GO:0000165 31 0.016
Mouse
muscle organ morphogenesis GO:0048644 4 0.016
cellular response to chemical stimulus GO:0070887 129 0.016
Mouse
muscle cell differentiation GO:0042692 171 0.016
Mouse
oxoacid metabolic process GO:0043436 47 0.016
neuron projection development GO:0031175 187 0.016
Zebrafish Mouse
organic cyclic compound catabolic process GO:1901361 119 0.015
Mouse
response to other organism GO:0051707 101 0.015
glycosyl compound catabolic process GO:1901658 79 0.015
Mouse
signal transduction by phosphorylation GO:0023014 31 0.015
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 87 0.015
Mouse
organic substance transport GO:0071702 113 0.015
Mouse
posttranscriptional regulation of gene expression GO:0010608 166 0.015
striated muscle cell differentiation GO:0051146 158 0.015
Mouse
muscle fiber development GO:0048747 2 0.015
regeneration GO:0031099 4 0.015
ribonucleoside triphosphate catabolic process GO:0009203 72 0.015
Mouse
molting cycle GO:0042303 281 0.015
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.015
negative regulation of wnt signaling pathway GO:0030178 6 0.015
phagocytosis engulfment GO:0006911 98 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.015
chromosome organization GO:0051276 104 0.015
regulation of mitotic cell cycle GO:0007346 76 0.015
regulation of stem cell differentiation GO:2000736 1 0.015
Mouse
neuromuscular junction development GO:0007528 2 0.014
nucleoside catabolic process GO:0009164 78 0.014
Mouse
carboxylic acid metabolic process GO:0019752 34 0.014
myosin filament organization GO:0031033 138 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.014
Mouse
purine nucleotide metabolic process GO:0006163 95 0.014
Mouse
regulation of response to stimulus GO:0048583 243 0.014
Human Mouse
ribonucleotide catabolic process GO:0009261 75 0.014
Mouse
purine ribonucleoside catabolic process GO:0046130 75 0.014
Mouse
positive regulation of protein metabolic process GO:0051247 45 0.014
Mouse
myofibril assembly GO:0030239 154 0.014
purine containing compound metabolic process GO:0072521 95 0.014
Mouse
hormone transport GO:0009914 2 0.014
Mouse
cell cycle g1 s phase transition GO:0044843 2 0.014
regulation of wnt signaling pathway GO:0030111 9 0.014
cell type specific apoptotic process GO:0097285 4 0.013
cell substrate adhesion GO:0031589 1 0.013
meiotic nuclear division GO:0007126 300 0.013
intracellular receptor signaling pathway GO:0030522 2 0.013
regulation of transferase activity GO:0051338 31 0.013
Mouse
cell morphogenesis GO:0000902 163 0.013
Zebrafish Mouse
regulation of cell proliferation GO:0042127 105 0.013
Mouse
purine ribonucleoside metabolic process GO:0046128 92 0.013
Mouse
cell junction organization GO:0034330 18 0.013
glycosyl compound metabolic process GO:1901657 100 0.013
Mouse
regulation of organ morphogenesis GO:2000027 4 0.013
cellular component morphogenesis GO:0032989 318 0.013
Zebrafish Mouse
engulfment of apoptotic cell GO:0043652 94 0.013
microtubule based process GO:0007017 182 0.013
ribonucleoside metabolic process GO:0009119 98 0.013
Mouse
regulation of response to wounding GO:1903034 1 0.013
positive regulation of hydrolase activity GO:0051345 38 0.013
asymmetric cell division GO:0008356 36 0.013
system process GO:0003008 136 0.013
heterocycle catabolic process GO:0046700 119 0.012
Mouse
response to topologically incorrect protein GO:0035966 82 0.012
establishment or maintenance of cell polarity GO:0007163 63 0.012
mitotic nuclear division GO:0007067 89 0.012
positive regulation of cell migration GO:0030335 3 0.012
nucleotide catabolic process GO:0009166 77 0.012
Mouse
cell proliferation GO:0008283 116 0.012
Mouse
endoderm development GO:0007492 20 0.012
chromosome segregation GO:0007059 180 0.012
neuron recognition GO:0008038 83 0.012
Zebrafish Mouse
epidermis development GO:0008544 24 0.012
generation of neurons GO:0048699 235 0.012
Zebrafish Mouse
positive regulation of phosphorylation GO:0042327 27 0.012
Mouse
gene silencing by rna GO:0031047 143 0.012
nucleobase containing small molecule metabolic process GO:0055086 115 0.012
Mouse
negative regulation of vulval development GO:0040027 206 0.012
regulation of canonical wnt signaling pathway GO:0060828 1 0.012
establishment of mitotic spindle localization GO:0040001 41 0.012
negative regulation of rna biosynthetic process GO:1902679 53 0.012
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.012
Mouse
regulation of cellular ketone metabolic process GO:0010565 3 0.011
regulation of gene expression epigenetic GO:0040029 163 0.011
organelle assembly GO:0070925 214 0.011
negative regulation of developmental process GO:0051093 227 0.011
Mouse
response to abiotic stimulus GO:0009628 152 0.011
positive regulation of chromosome organization GO:2001252 2 0.011
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.011
organic acid metabolic process GO:0006082 47 0.011
single organism signaling GO:0044700 401 0.011
posttranscriptional gene silencing GO:0016441 143 0.011
posttranscriptional gene silencing by rna GO:0035194 143 0.011
regulation of locomotion GO:0040012 161 0.011
Human Mouse
regulation of gastrulation GO:0010470 4 0.011
negative regulation of cell communication GO:0010648 61 0.011
regulation of cytoskeleton organization GO:0051493 41 0.011
Mouse
negative regulation of multicellular organismal process GO:0051241 236 0.011
Mouse Worm
g1 s transition of mitotic cell cycle GO:0000082 2 0.011
mitotic sister chromatid segregation GO:0000070 38 0.011
axonal fasciculation GO:0007413 79 0.011
tube formation GO:0035148 2 0.011
gtp catabolic process GO:0006184 46 0.011
Mouse
purine ribonucleotide catabolic process GO:0009154 75 0.011
Mouse
cellular response to topologically incorrect protein GO:0035967 76 0.011
nematode male tail tip morphogenesis GO:0045138 77 0.011
Worm
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.011
Mouse
purine nucleoside catabolic process GO:0006152 75 0.011
Mouse
response to external biotic stimulus GO:0043207 101 0.011
neurogenesis GO:0022008 236 0.011
Zebrafish Mouse
pigmentation GO:0043473 2 0.010
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.010
nucleotide metabolic process GO:0009117 108 0.010
Mouse
striated muscle myosin thick filament assembly GO:0071688 138 0.010
regulation of signal transduction GO:0009966 135 0.010
Mouse
ribonucleoside catabolic process GO:0042454 77 0.010
Mouse
amine metabolic process GO:0009308 15 0.010
ribose phosphate metabolic process GO:0019693 99 0.010
Mouse
synaptic growth at neuromuscular junction GO:0051124 1 0.010
actomyosin structure organization GO:0031032 154 0.010
negative regulation of cellular metabolic process GO:0031324 95 0.010
Mouse
cellular ketone metabolic process GO:0042180 14 0.010
development of primary male sexual characteristics GO:0046546 4 0.010

vab-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011