Caenorhabditis elegans

51 known processes

gcs-1 (CELE_F37B12.2)

Protein GCS-1

gcs-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of localization GO:0051234 1171 0.486
vesicle mediated transport GO:0016192 852 0.372
developmental process involved in reproduction GO:0003006 1165 0.364
receptor mediated endocytosis GO:0006898 715 0.352
organelle organization GO:0006996 783 0.320
endocytosis GO:0006897 819 0.307
embryo development ending in birth or egg hatching GO:0009792 2992 0.304
cytoskeleton organization GO:0007010 339 0.260
organelle fission GO:0048285 363 0.247
post embryonic development GO:0009791 2152 0.240
meiotic nuclear division GO:0007126 300 0.225
cell development GO:0048468 696 0.208
reproductive structure development GO:0048608 850 0.206
single organism reproductive process GO:0044702 1196 0.185
embryo development GO:0009790 3052 0.179
locomotion GO:0040011 1634 0.177
protein complex subunit organization GO:0071822 280 0.162
transport GO:0006810 1093 0.160
aging GO:0007568 812 0.151
determination of adult lifespan GO:0008340 812 0.131
development of primary sexual characteristics GO:0045137 840 0.129
ovulation GO:0030728 33 0.129
gene expression GO:0010467 412 0.125
Human
cellular component morphogenesis GO:0032989 318 0.121
response to external stimulus GO:0009605 289 0.121
neurogenesis GO:0022008 236 0.119
gonad development GO:0008406 840 0.116
body morphogenesis GO:0010171 620 0.114
small molecule metabolic process GO:0044281 186 0.111
single organism localization GO:1902578 518 0.110
cellular biosynthetic process GO:0044249 315 0.105
taxis GO:0042330 128 0.104
multicellular organismal aging GO:0010259 812 0.103
biosynthetic process GO:0009058 323 0.102
macromolecule localization GO:0033036 771 0.101
single organism catabolic process GO:0044712 129 0.101
nervous system development GO:0007399 253 0.099
regulation of biological quality GO:0065008 741 0.095
Human
phosphorus metabolic process GO:0006793 232 0.095
sex differentiation GO:0007548 909 0.094
multicellular organismal reproductive process GO:0048609 815 0.092
organ development GO:0048513 1102 0.092
regulation of multicellular organismal process GO:0051239 726 0.091
germ cell development GO:0007281 351 0.090
multicellular organism reproduction GO:0032504 819 0.090
regulation of organelle organization GO:0033043 164 0.089
cell projection organization GO:0030030 231 0.087
cell death GO:0008219 547 0.085
Human
reproductive system development GO:0061458 850 0.084
neuron projection development GO:0031175 187 0.082
nucleobase containing compound metabolic process GO:0006139 406 0.081
Human
cell cycle GO:0007049 526 0.079
aromatic compound biosynthetic process GO:0019438 192 0.077
Human
multi organism reproductive process GO:0044703 867 0.077
maintenance of location GO:0051235 580 0.077
establishment of localization in cell GO:0051649 318 0.076
organic substance catabolic process GO:1901575 294 0.075
positive regulation of developmental process GO:0051094 408 0.075
system process GO:0003008 136 0.073
Human
oocyte differentiation GO:0009994 45 0.073
phosphate containing compound metabolic process GO:0006796 232 0.073
lipid storage GO:0019915 565 0.073
oxoacid metabolic process GO:0043436 47 0.072
actin cytoskeleton organization GO:0030036 184 0.070
single organism transport GO:0044765 447 0.069
gamete generation GO:0007276 461 0.067
behavior GO:0007610 527 0.067
neuron differentiation GO:0030182 217 0.066
regulation of cell cycle process GO:0010564 145 0.066
actin filament based process GO:0030029 191 0.065
apoptotic process GO:0006915 478 0.064
Human
sexual reproduction GO:0019953 546 0.064
cellular protein complex assembly GO:0043623 178 0.063
regulation of developmental process GO:0050793 684 0.063
positive regulation of cellular process GO:0048522 332 0.063
guanosine containing compound catabolic process GO:1901069 48 0.062
lipid localization GO:0010876 573 0.062
anatomical structure formation involved in morphogenesis GO:0048646 250 0.061
defense response to bacterium GO:0042742 86 0.061
hermaphrodite genitalia development GO:0040035 734 0.060
cellular response to stress GO:0033554 162 0.060
regulation of developmental growth GO:0048638 389 0.058
neuron development GO:0048666 199 0.057
carboxylic acid metabolic process GO:0019752 34 0.056
regulation of multicellular organismal development GO:2000026 317 0.055
endosomal transport GO:0016197 26 0.053
regulation of localization GO:0032879 194 0.053
muscle structure development GO:0061061 191 0.053
organonitrogen compound metabolic process GO:1901564 151 0.053
nucleotide metabolic process GO:0009117 108 0.052
cellular ketone metabolic process GO:0042180 14 0.052
death GO:0016265 547 0.051
Human
meiotic chromosome segregation GO:0045132 139 0.051
positive regulation of growth GO:0045927 369 0.051
single organism organelle organization GO:1902589 501 0.051
cytokinesis GO:0000910 80 0.050
heterocycle catabolic process GO:0046700 119 0.050
cellular nitrogen compound biosynthetic process GO:0044271 192 0.049
regulation of actin filament based process GO:0032970 22 0.049
golgi vesicle transport GO:0048193 3 0.049
positive regulation of multicellular organism growth GO:0040018 352 0.048
catabolic process GO:0009056 318 0.048
cellular component assembly GO:0022607 293 0.048
meiotic cell cycle process GO:1903046 170 0.048
protein metabolic process GO:0019538 422 0.047
female gamete generation GO:0007292 254 0.046
response to oxygen containing compound GO:1901700 44 0.046
developmental growth GO:0048589 412 0.045
chromosome segregation GO:0007059 180 0.044
protein complex assembly GO:0006461 186 0.044
growth GO:0040007 562 0.044
signal transduction GO:0007165 317 0.043
small gtpase mediated signal transduction GO:0007264 32 0.042
regulation of growth GO:0040008 409 0.042
negative regulation of vulval development GO:0040027 206 0.042
positive regulation of phosphate metabolic process GO:0045937 56 0.041
neuron recognition GO:0008038 83 0.041
rho protein signal transduction GO:0007266 2 0.041
cellular component biogenesis GO:0044085 297 0.040
striated muscle cell differentiation GO:0051146 158 0.040
macromolecular complex assembly GO:0065003 193 0.040
cellular macromolecule biosynthetic process GO:0034645 247 0.040
Human
regulation of intracellular signal transduction GO:1902531 77 0.040
negative regulation of biological process GO:0048519 567 0.039
Human
protein complex biogenesis GO:0070271 186 0.039
protein modification process GO:0036211 207 0.039
organophosphate metabolic process GO:0019637 125 0.038
multicellular organism growth GO:0035264 385 0.038
cellular protein modification process GO:0006464 207 0.038
regulation of cellular ketone metabolic process GO:0010565 3 0.038
genitalia development GO:0048806 741 0.037
immune response GO:0006955 192 0.037
regulation of transport GO:0051049 91 0.037
oogenesis GO:0048477 229 0.037
response to transition metal nanoparticle GO:1990267 18 0.037
cell migration GO:0016477 306 0.036
embryonic morphogenesis GO:0048598 152 0.036
regulation of locomotion GO:0040012 161 0.036
response to chemical GO:0042221 356 0.036
organelle assembly GO:0070925 214 0.035
positive regulation of multicellular organismal process GO:0051240 417 0.035
protein localization GO:0008104 205 0.035
intracellular transport GO:0046907 77 0.035
signaling GO:0023052 401 0.035
negative regulation of post embryonic development GO:0048581 208 0.035
chemotaxis GO:0006935 120 0.034
cell part morphogenesis GO:0032990 152 0.034
purine containing compound catabolic process GO:0072523 75 0.034
cell morphogenesis GO:0000902 163 0.034
multi multicellular organism process GO:0044706 390 0.033
positive regulation of cell projection organization GO:0031346 4 0.033
axonal fasciculation GO:0007413 79 0.033
meiotic cell cycle GO:0051321 335 0.032
positive regulation of developmental growth GO:0048639 354 0.032
organic substance biosynthetic process GO:1901576 323 0.032
muscle cell development GO:0055001 158 0.032
single organism intracellular transport GO:1902582 70 0.032
negative regulation of nematode larval development GO:0061064 208 0.031
purine nucleotide metabolic process GO:0006163 95 0.031
actomyosin structure organization GO:0031032 154 0.031
cell motility GO:0048870 313 0.031
cell projection morphogenesis GO:0048858 148 0.031
regulation of filopodium assembly GO:0051489 2 0.031
phagocytosis engulfment GO:0006911 98 0.030
oocyte development GO:0048599 44 0.030
amine metabolic process GO:0009308 15 0.030
cellular macromolecular complex assembly GO:0034622 184 0.030
oviposition GO:0018991 364 0.030
regulation of multicellular organism growth GO:0040014 373 0.030
reproductive behavior GO:0019098 387 0.029
cellular amine metabolic process GO:0044106 15 0.029
glycosyl compound catabolic process GO:1901658 79 0.029
intracellular signal transduction GO:0035556 96 0.029
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.028
localization of cell GO:0051674 313 0.028
myofibril assembly GO:0030239 154 0.028
nucleoside phosphate metabolic process GO:0006753 108 0.028
defense response GO:0006952 296 0.028
positive regulation of phosphorus metabolic process GO:0010562 56 0.028
peptidyl amino acid modification GO:0018193 58 0.028
nucleoside metabolic process GO:0009116 99 0.028
single organism signaling GO:0044700 401 0.028
regulation of cytoplasmic transport GO:1903649 3 0.027
purine ribonucleoside metabolic process GO:0046128 92 0.027
striated muscle myosin thick filament assembly GO:0071688 138 0.027
cellular component movement GO:0006928 388 0.027
myosin filament organization GO:0031033 138 0.027
cell division GO:0051301 262 0.027
nucleobase containing small molecule metabolic process GO:0055086 115 0.027
apoptotic cell clearance GO:0043277 111 0.027
organic acid metabolic process GO:0006082 47 0.026
regulation of anatomical structure size GO:0090066 46 0.026
Human
nucleotide catabolic process GO:0009166 77 0.026
regulation of cellular localization GO:0060341 42 0.026
cell proliferation GO:0008283 116 0.026
macromolecule modification GO:0043412 218 0.025
regulation of cytoskeleton organization GO:0051493 41 0.025
aromatic compound catabolic process GO:0019439 116 0.025
response to biotic stimulus GO:0009607 101 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.025
peptidyl tyrosine phosphorylation GO:0018108 2 0.025
membrane organization GO:0061024 135 0.025
organic substance transport GO:0071702 113 0.025
ras protein signal transduction GO:0007265 31 0.025
organic cyclic compound biosynthetic process GO:1901362 195 0.025
Human
inductive cell migration GO:0040039 145 0.024
protein phosphorylation GO:0006468 85 0.024
multi organism reproductive behavior GO:0044705 387 0.024
innate immune response GO:0045087 190 0.024
response to wounding GO:0009611 4 0.024
head development GO:0060322 1 0.024
regulation of cellular biosynthetic process GO:0031326 189 0.024
Human
regulation of gene expression GO:0010468 366 0.023
Human
response to heat GO:0009408 50 0.023
cellular protein metabolic process GO:0044267 279 0.023
nucleoside triphosphate catabolic process GO:0009143 72 0.023
cellular catabolic process GO:0044248 199 0.023
phagocytosis GO:0006909 115 0.023
multicellular organismal reproductive behavior GO:0033057 384 0.023
macromolecular complex subunit organization GO:0043933 320 0.023
cellular nitrogen compound catabolic process GO:0044270 119 0.023
carbohydrate derivative metabolic process GO:1901135 141 0.023
multi organism behavior GO:0051705 389 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
regulation of transcription dna templated GO:0006355 164 0.022
Human
neuromuscular junction development GO:0007528 2 0.022
regulation of cell projection assembly GO:0060491 3 0.022
negative regulation of cellular process GO:0048523 239 0.022
Human
ribonucleoside metabolic process GO:0009119 98 0.022
neuron projection guidance GO:0097485 82 0.022
regulation of post embryonic development GO:0048580 260 0.022
regulation of apoptotic signaling pathway GO:2001233 1 0.022
post embryonic organ development GO:0048569 336 0.022
vulval development GO:0040025 333 0.022
positive regulation of molecular function GO:0044093 61 0.021
phosphorylation GO:0016310 116 0.021
protein polymerization GO:0051258 26 0.021
membrane invagination GO:0010324 98 0.021
regulation of apoptotic process GO:0042981 36 0.021
Human
purine nucleotide catabolic process GO:0006195 75 0.021
glycosyl compound metabolic process GO:1901657 100 0.021
negative regulation of developmental process GO:0051093 227 0.021
ribonucleoside triphosphate catabolic process GO:0009203 72 0.020
cell recognition GO:0008037 85 0.020
single organism behavior GO:0044708 83 0.020
ribonucleoside triphosphate metabolic process GO:0009199 87 0.020
regulation of nucleocytoplasmic transport GO:0046822 3 0.020
regulation of phosphorus metabolic process GO:0051174 81 0.020
response to other organism GO:0051707 101 0.020
negative regulation of response to stimulus GO:0048585 73 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.020
macromolecule biosynthetic process GO:0009059 250 0.019
Human
guanosine containing compound metabolic process GO:1901068 49 0.019
dauer larval development GO:0040024 92 0.019
engulfment of apoptotic cell GO:0043652 94 0.019
muscle cell differentiation GO:0042692 171 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.019
myosin filament assembly GO:0031034 138 0.019
regulation of macromolecule metabolic process GO:0060255 421 0.019
Human
heterocycle biosynthetic process GO:0018130 187 0.019
Human
nitrogen compound transport GO:0071705 49 0.019
carbohydrate derivative catabolic process GO:1901136 82 0.019
defense response to gram negative bacterium GO:0050829 64 0.019
response to external biotic stimulus GO:0043207 101 0.019
posttranscriptional regulation of gene expression GO:0010608 166 0.019
positive regulation of gtpase activity GO:0043547 28 0.018
cellular protein localization GO:0034613 75 0.018
regulation of rna metabolic process GO:0051252 173 0.018
Human
cell growth GO:0016049 44 0.018
ribose phosphate metabolic process GO:0019693 99 0.018
nucleoside phosphate catabolic process GO:1901292 77 0.018
regulation of cellular metabolic process GO:0031323 305 0.018
Human
programmed cell death GO:0012501 500 0.018
Human
regulation of nuclear division GO:0051783 115 0.018
response to bacterium GO:0009617 86 0.018
defense response to other organism GO:0098542 100 0.018
cell cycle process GO:0022402 482 0.018
cell type specific apoptotic process GO:0097285 4 0.017
secretion by cell GO:0032940 138 0.017
regulation of response to stimulus GO:0048583 243 0.017
mitotic nuclear division GO:0007067 89 0.017
regulation of nematode larval development GO:0061062 260 0.017
gene silencing by rna GO:0031047 143 0.017
ribonucleotide metabolic process GO:0009259 99 0.017
cellular response to abiotic stimulus GO:0071214 4 0.017
purine ribonucleotide metabolic process GO:0009150 95 0.017
gtp metabolic process GO:0046039 46 0.017
regulation of oviposition GO:0046662 43 0.017
axon development GO:0061564 163 0.017
autophagy GO:0006914 29 0.017
striated muscle cell development GO:0055002 157 0.016
purine nucleoside metabolic process GO:0042278 92 0.016
spindle organization GO:0007051 92 0.016
lipid metabolic process GO:0006629 77 0.016
gtp catabolic process GO:0006184 46 0.016
purine nucleoside triphosphate metabolic process GO:0009144 87 0.016
organic cyclic compound catabolic process GO:1901361 119 0.016
cellular amino acid metabolic process GO:0006520 15 0.015
single organism carbohydrate metabolic process GO:0044723 29 0.015
regulation of cellular component organization GO:0051128 248 0.015
negative regulation of multicellular organismal process GO:0051241 236 0.015
rna localization GO:0006403 3 0.015
regulation of gtp catabolic process GO:0033124 32 0.015
actin filament bundle assembly GO:0051017 3 0.015
regulation of protein import into nucleus GO:0042306 3 0.015
cation transport GO:0006812 78 0.015
purine ribonucleotide catabolic process GO:0009154 75 0.015
purine containing compound metabolic process GO:0072521 95 0.015
cellular component assembly involved in morphogenesis GO:0010927 183 0.014
dendrite development GO:0016358 42 0.014
cognition GO:0050890 27 0.014
signal transduction by phosphorylation GO:0023014 31 0.014
regulation of signal transduction GO:0009966 135 0.014
cellular macromolecule localization GO:0070727 75 0.014
regulation of cell migration GO:0030334 55 0.014
nucleobase containing compound biosynthetic process GO:0034654 184 0.014
Human
regulation of reproductive process GO:2000241 66 0.014
memory GO:0007613 3 0.014
oocyte construction GO:0007308 2 0.014
nucleobase containing compound catabolic process GO:0034655 114 0.014
regulation of cellular component size GO:0032535 40 0.014
peptidyl tyrosine modification GO:0018212 3 0.014
posttranscriptional gene silencing GO:0016441 143 0.014
positive regulation of synaptic transmission GO:0050806 24 0.013
rna metabolic process GO:0016070 228 0.013
Human
macroautophagy GO:0016236 11 0.013
regulation of gtpase activity GO:0043087 30 0.013
regulation of response to wounding GO:1903034 1 0.013
nucleic acid metabolic process GO:0090304 299 0.013
Human
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.013
Human
cellular homeostasis GO:0019725 22 0.013
Human
regulation of vulval development GO:0040028 248 0.013
regulation of gene expression epigenetic GO:0040029 163 0.012
response to acid chemical GO:0001101 4 0.012
posttranscriptional gene silencing by rna GO:0035194 143 0.012
neurological system process GO:0050877 53 0.012
positive regulation of nematode larval development GO:0061063 54 0.012
positive regulation of phosphorylation GO:0042327 27 0.012
pigmentation GO:0043473 2 0.012
g1 s transition of mitotic cell cycle GO:0000082 2 0.012
regulation of catalytic activity GO:0050790 78 0.012
g protein coupled receptor signaling pathway GO:0007186 46 0.012
regulation of protein targeting GO:1903533 3 0.012
response to temperature stimulus GO:0009266 66 0.012
tube development GO:0035295 126 0.012
organophosphate catabolic process GO:0046434 81 0.012
response to metal ion GO:0010038 33 0.012
mapk cascade GO:0000165 31 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.012
regulation of multi organism process GO:0043900 69 0.012
filopodium assembly GO:0046847 2 0.012
regulation of cell differentiation GO:0045595 81 0.011
cellular localization GO:0051641 360 0.011
negative regulation of cell communication GO:0010648 61 0.011
regulation of nitrogen compound metabolic process GO:0051171 222 0.011
Human
developmental maturation GO:0021700 26 0.011
regulation of cellular component movement GO:0051270 62 0.011
organonitrogen compound biosynthetic process GO:1901566 44 0.011
response to endoplasmic reticulum stress GO:0034976 71 0.011
cellular lipid metabolic process GO:0044255 40 0.011
macromolecule glycosylation GO:0043413 18 0.011
muscle tissue development GO:0060537 1 0.011
regulation of cell communication GO:0010646 176 0.011
negative regulation of signaling GO:0023057 61 0.011
collagen and cuticulin based cuticle development GO:0040002 99 0.011
regulation of cell proliferation GO:0042127 105 0.011
rna interference GO:0016246 137 0.011
regulation of metabolic process GO:0019222 478 0.011
Human
positive regulation of catalytic activity GO:0043085 59 0.011
digestive tract development GO:0048565 122 0.010
regulation of kinase activity GO:0043549 29 0.010
ribonucleotide catabolic process GO:0009261 75 0.010
sensory organ morphogenesis GO:0090596 2 0.010
establishment of organelle localization GO:0051656 123 0.010
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.010
Human
rna biosynthetic process GO:0032774 169 0.010
Human
somatic muscle development GO:0007525 1 0.010
negative regulation of metabolic process GO:0009892 240 0.010
Human
purine nucleoside catabolic process GO:0006152 75 0.010

gcs-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.011