Caenorhabditis elegans

23 known processes

ptl-1 (CELE_F42G9.9)

Protein PTL-1

ptl-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.465
regulation of developmental process GO:0050793 684 0.329
regulation of multicellular organismal process GO:0051239 726 0.311
signaling GO:0023052 401 0.291
Fly
embryo development ending in birth or egg hatching GO:0009792 2992 0.251
cell development GO:0048468 696 0.198
multicellular organismal reproductive process GO:0048609 815 0.194
ion transmembrane transport GO:0034220 91 0.194
multicellular organism reproduction GO:0032504 819 0.193
locomotion GO:0040011 1634 0.192
single organism signaling GO:0044700 401 0.190
Fly
vesicle mediated transport GO:0016192 852 0.170
regulation of locomotion GO:0040012 161 0.145
negative regulation of biological process GO:0048519 567 0.139
regulation of cellular metabolic process GO:0031323 305 0.139
response to chemical GO:0042221 356 0.138
establishment of localization GO:0051234 1171 0.137
transport GO:0006810 1093 0.137
organic substance catabolic process GO:1901575 294 0.133
cell cell signaling GO:0007267 118 0.129
Fly
cellular component morphogenesis GO:0032989 318 0.128
behavior GO:0007610 527 0.125
regulation of response to stimulus GO:0048583 243 0.123
nucleobase containing compound metabolic process GO:0006139 406 0.123
catabolic process GO:0009056 318 0.122
multi organism reproductive process GO:0044703 867 0.116
single organism reproductive process GO:0044702 1196 0.113
organ development GO:0048513 1102 0.112
protein complex subunit organization GO:0071822 280 0.110
signal transduction GO:0007165 317 0.108
regulation of cellular biosynthetic process GO:0031326 189 0.107
regulation of neurotransmitter levels GO:0001505 36 0.104
regulation of gene expression GO:0010468 366 0.104
regulation of signaling GO:0023051 172 0.101
single organism organelle organization GO:1902589 501 0.097
organic substance biosynthetic process GO:1901576 323 0.097
system process GO:0003008 136 0.095
synaptic transmission GO:0007268 106 0.094
positive regulation of rna metabolic process GO:0051254 103 0.090
endocytosis GO:0006897 819 0.090
hermaphrodite genitalia development GO:0040035 734 0.089
gene expression GO:0010467 412 0.088
positive regulation of multicellular organismal process GO:0051240 417 0.088
regulation of primary metabolic process GO:0080090 292 0.087
heterocycle biosynthetic process GO:0018130 187 0.083
regulation of cellular component organization GO:0051128 248 0.082
regulation of macromolecule metabolic process GO:0060255 421 0.081
macromolecular complex assembly GO:0065003 193 0.079
regulation of metabolic process GO:0019222 478 0.078
positive regulation of cellular process GO:0048522 332 0.078
post embryonic development GO:0009791 2152 0.078
transcription from rna polymerase ii promoter GO:0006366 149 0.077
negative regulation of metabolic process GO:0009892 240 0.076
macromolecule localization GO:0033036 771 0.074
positive regulation of developmental process GO:0051094 408 0.074
macromolecular complex subunit organization GO:0043933 320 0.072
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.070
anatomical structure formation involved in morphogenesis GO:0048646 250 0.070
defense response GO:0006952 296 0.070
meiotic cell cycle GO:0051321 335 0.069
cell cycle GO:0007049 526 0.068
lipid localization GO:0010876 573 0.067
cellular component assembly GO:0022607 293 0.066
growth GO:0040007 562 0.065
multicellular organism growth GO:0035264 385 0.065
positive regulation of nucleic acid templated transcription GO:1903508 102 0.065
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.064
cytoskeleton organization GO:0007010 339 0.064
regulation of growth GO:0040008 409 0.064
regulation of biosynthetic process GO:0009889 189 0.063
regulation of biological quality GO:0065008 741 0.062
negative regulation of cellular process GO:0048523 239 0.062
developmental process involved in reproduction GO:0003006 1165 0.060
regulation of cell communication GO:0010646 176 0.060
single organism transport GO:0044765 447 0.060
determination of adult lifespan GO:0008340 812 0.060
single organism cellular localization GO:1902580 72 0.060
cell cycle process GO:0022402 482 0.059
single organism localization GO:1902578 518 0.059
protein complex biogenesis GO:0070271 186 0.059
cellular component biogenesis GO:0044085 297 0.059
maintenance of location GO:0051235 580 0.056
death GO:0016265 547 0.056
cellular protein localization GO:0034613 75 0.055
protein complex assembly GO:0006461 186 0.055
response to biotic stimulus GO:0009607 101 0.054
lipid storage GO:0019915 565 0.054
genitalia development GO:0048806 741 0.054
multicellular organismal aging GO:0010259 812 0.054
positive regulation of cell communication GO:0010647 69 0.053
regulation of developmental growth GO:0048638 389 0.052
immune response GO:0006955 192 0.052
regulation of neurogenesis GO:0050767 40 0.052
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.052
gamete generation GO:0007276 461 0.051
cellular response to chemical stimulus GO:0070887 129 0.051
regulation of cell morphogenesis GO:0022604 40 0.051
body morphogenesis GO:0010171 620 0.050
establishment of localization in cell GO:0051649 318 0.050
rna metabolic process GO:0016070 228 0.049
organelle organization GO:0006996 783 0.048
muscle structure development GO:0061061 191 0.047
positive regulation of cellular biosynthetic process GO:0031328 109 0.047
cell projection organization GO:0030030 231 0.046
regulation of synaptic transmission GO:0050804 34 0.046
carbohydrate derivative metabolic process GO:1901135 141 0.046
multi organism reproductive behavior GO:0044705 387 0.046
germ cell development GO:0007281 351 0.046
regulation of multicellular organismal development GO:2000026 317 0.046
neurogenesis GO:0022008 236 0.046
positive regulation of metabolic process GO:0009893 187 0.045
cell surface receptor signaling pathway GO:0007166 149 0.045
sex differentiation GO:0007548 909 0.044
cell fate commitment GO:0045165 139 0.044
Fly
regulation of transport GO:0051049 91 0.044
regulation of macromolecule biosynthetic process GO:0010556 189 0.044
pattern specification process GO:0007389 59 0.043
reproductive structure development GO:0048608 850 0.043
reproductive system development GO:0061458 850 0.043
regulation of cell differentiation GO:0045595 81 0.042
cellular response to organic substance GO:0071310 119 0.042
secretion by cell GO:0032940 138 0.042
positive regulation of growth GO:0045927 369 0.042
female gamete generation GO:0007292 254 0.042
cellular protein complex assembly GO:0043623 178 0.042
cellular localization GO:0051641 360 0.041
negative regulation of macromolecule metabolic process GO:0010605 229 0.041
regulation of cell cycle GO:0051726 194 0.041
cellular biosynthetic process GO:0044249 315 0.040
guanosine containing compound metabolic process GO:1901068 49 0.040
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.040
cellular catabolic process GO:0044248 199 0.040
protein metabolic process GO:0019538 422 0.039
ion transport GO:0006811 113 0.039
meiotic nuclear division GO:0007126 300 0.039
macromolecule biosynthetic process GO:0009059 250 0.039
neuron development GO:0048666 199 0.039
biosynthetic process GO:0009058 323 0.039
rna biosynthetic process GO:0032774 169 0.038
regulation of cell development GO:0060284 49 0.038
development of primary sexual characteristics GO:0045137 840 0.037
sexual reproduction GO:0019953 546 0.037
gonad development GO:0008406 840 0.037
embryonic morphogenesis GO:0048598 152 0.036
cell death GO:0008219 547 0.036
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.036
negative regulation of gene expression GO:0010629 217 0.035
regulation of nucleic acid templated transcription GO:1903506 165 0.035
cellular protein metabolic process GO:0044267 279 0.035
positive regulation of macromolecule metabolic process GO:0010604 149 0.035
nucleic acid metabolic process GO:0090304 299 0.035
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.034
response to other organism GO:0051707 101 0.034
transcription dna templated GO:0006351 168 0.034
positive regulation of cellular metabolic process GO:0031325 178 0.034
response to external biotic stimulus GO:0043207 101 0.034
developmental growth GO:0048589 412 0.033
innate immune response GO:0045087 190 0.032
reproductive behavior GO:0019098 387 0.032
phagocytosis GO:0006909 115 0.032
cellular nitrogen compound catabolic process GO:0044270 119 0.031
regulation of nitrogen compound metabolic process GO:0051171 222 0.031
tissue development GO:0009888 112 0.030
apoptotic process GO:0006915 478 0.030
regulation of nervous system development GO:0051960 41 0.030
regulation of multicellular organism growth GO:0040014 373 0.030
meiotic cell cycle process GO:1903046 170 0.030
oogenesis GO:0048477 229 0.030
positive regulation of neurogenesis GO:0050769 4 0.029
neuron differentiation GO:0030182 217 0.029
tube development GO:0035295 126 0.029
positive regulation of signaling GO:0023056 66 0.029
multicellular organismal reproductive behavior GO:0033057 384 0.029
cellular macromolecular complex assembly GO:0034622 184 0.029
response to wounding GO:0009611 4 0.028
cellular macromolecule biosynthetic process GO:0034645 247 0.028
protein catabolic process GO:0030163 162 0.028
cellular component movement GO:0006928 388 0.028
positive regulation of rna biosynthetic process GO:1902680 102 0.027
heterocycle catabolic process GO:0046700 119 0.027
organic cyclic compound biosynthetic process GO:1901362 195 0.027
organelle assembly GO:0070925 214 0.027
negative regulation of multicellular organismal process GO:0051241 236 0.027
aging GO:0007568 812 0.027
programmed cell death GO:0012501 500 0.027
nucleotide catabolic process GO:0009166 77 0.027
positive regulation of developmental growth GO:0048639 354 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.026
small molecule metabolic process GO:0044281 186 0.026
aromatic compound catabolic process GO:0019439 116 0.026
single organism catabolic process GO:0044712 129 0.026
eating behavior GO:0042755 59 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.026
regulation of pharyngeal pumping GO:0043051 36 0.026
cellular macromolecule localization GO:0070727 75 0.026
nucleobase containing small molecule metabolic process GO:0055086 115 0.025
organonitrogen compound catabolic process GO:1901565 90 0.025
response to organic substance GO:0010033 131 0.025
post embryonic organ development GO:0048569 336 0.025
small gtpase mediated signal transduction GO:0007264 32 0.025
regulation of transcription dna templated GO:0006355 164 0.025
digestive tract development GO:0048565 122 0.024
actin filament based process GO:0030029 191 0.024
epithelium development GO:0060429 68 0.024
defense response to other organism GO:0098542 100 0.024
organic substance transport GO:0071702 113 0.024
regulation of rna metabolic process GO:0051252 173 0.024
oviposition GO:0018991 364 0.024
intracellular signal transduction GO:0035556 96 0.024
regulation of anatomical structure morphogenesis GO:0022603 51 0.024
pharyngeal pumping GO:0043050 58 0.023
nucleoside triphosphate metabolic process GO:0009141 87 0.023
regulation of oviposition GO:0046662 43 0.023
organophosphate metabolic process GO:0019637 125 0.023
feeding behavior GO:0007631 70 0.023
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.023
organelle fission GO:0048285 363 0.023
transmembrane transport GO:0055085 110 0.023
multi organism behavior GO:0051705 389 0.023
generation of neurons GO:0048699 235 0.022
cell division GO:0051301 262 0.022
glycosyl compound metabolic process GO:1901657 100 0.022
gtp metabolic process GO:0046039 46 0.022
regulation of behavior GO:0050795 97 0.022
digestive system development GO:0055123 122 0.021
multi multicellular organism process GO:0044706 390 0.021
regulation of neuron differentiation GO:0045664 40 0.021
macromolecule modification GO:0043412 218 0.021
hormone transport GO:0009914 2 0.021
striated muscle cell differentiation GO:0051146 158 0.021
establishment of vesicle localization GO:0051650 23 0.021
organic cyclic compound catabolic process GO:1901361 119 0.021
phosphorus metabolic process GO:0006793 232 0.021
phosphate containing compound metabolic process GO:0006796 232 0.021
nucleobase containing compound catabolic process GO:0034655 114 0.021
receptor mediated endocytosis GO:0006898 715 0.021
regulation of cell cycle process GO:0010564 145 0.021
nucleoside triphosphate catabolic process GO:0009143 72 0.021
mitotic spindle organization GO:0007052 81 0.021
positive regulation of biosynthetic process GO:0009891 109 0.021
g protein coupled receptor signaling pathway GO:0007186 46 0.021
nucleic acid templated transcription GO:0097659 169 0.021
organonitrogen compound metabolic process GO:1901564 151 0.021
ectoderm development GO:0007398 3 0.020
cell motility GO:0048870 313 0.020
purine nucleoside triphosphate metabolic process GO:0009144 87 0.020
ribonucleoside triphosphate catabolic process GO:0009203 72 0.020
nucleobase containing compound biosynthetic process GO:0034654 184 0.020
tube morphogenesis GO:0035239 79 0.020
negative regulation of developmental process GO:0051093 227 0.020
cell migration GO:0016477 306 0.020
positive regulation of gene expression GO:0010628 112 0.020
regulation of signal transduction GO:0009966 135 0.020
protein localization GO:0008104 205 0.020
ribonucleoside metabolic process GO:0009119 98 0.020
actin cytoskeleton organization GO:0030036 184 0.020
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.020
regulation of cell proliferation GO:0042127 105 0.019
regulation of gtp catabolic process GO:0033124 32 0.019
positive regulation of gtpase activity GO:0043547 28 0.019
enzyme linked receptor protein signaling pathway GO:0007167 50 0.019
protein modification process GO:0036211 207 0.019
cell morphogenesis GO:0000902 163 0.019
regulation of molecular function GO:0065009 89 0.019
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.019
molting cycle GO:0042303 281 0.019
positive regulation of neuron differentiation GO:0045666 4 0.019
ras protein signal transduction GO:0007265 31 0.019
mechanosensory behavior GO:0007638 25 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.019
pigmentation GO:0043473 2 0.018
gtp catabolic process GO:0006184 46 0.018
head development GO:0060322 1 0.018
sensory organ morphogenesis GO:0090596 2 0.018
negative regulation of rna biosynthetic process GO:1902679 53 0.018
regulation of rna biosynthetic process GO:2001141 165 0.018
cation transport GO:0006812 78 0.018
rho protein signal transduction GO:0007266 2 0.018
secretion GO:0046903 147 0.018
posttranscriptional regulation of gene expression GO:0010608 166 0.018
protein oligomerization GO:0051259 4 0.018
establishment of organelle localization GO:0051656 123 0.018
regulation of gene expression epigenetic GO:0040029 163 0.017
membrane organization GO:0061024 135 0.017
purine ribonucleoside catabolic process GO:0046130 75 0.017
excretion GO:0007588 49 0.017
positive regulation of molecular function GO:0044093 61 0.017
collagen and cuticulin based cuticle development GO:0040002 99 0.017
regulation of localization GO:0032879 194 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.017
myosin filament assembly GO:0031034 138 0.017
regulation of exocytosis GO:0017157 1 0.017
regionalization GO:0003002 31 0.017
cellular nitrogen compound biosynthetic process GO:0044271 192 0.017
regulation of cellular catabolic process GO:0031329 51 0.017
positive regulation of cell cycle GO:0045787 55 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.016
striated muscle cell development GO:0055002 157 0.016
nucleoside metabolic process GO:0009116 99 0.016
peptide hormone secretion GO:0030072 2 0.016
regulation of gtpase activity GO:0043087 30 0.016
cuticle development GO:0042335 100 0.016
positive regulation of multicellular organism growth GO:0040018 352 0.016
cellular response to growth factor stimulus GO:0071363 18 0.016
neuromuscular junction development GO:0007528 2 0.016
positive regulation of signal transduction GO:0009967 40 0.016
cell part morphogenesis GO:0032990 152 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.016
myofibril assembly GO:0030239 154 0.016
neuron projection development GO:0031175 187 0.016
ribonucleoside catabolic process GO:0042454 77 0.016
negative regulation of cellular component organization GO:0051129 33 0.015
cellular response to abiotic stimulus GO:0071214 4 0.015
cellular component assembly involved in morphogenesis GO:0010927 183 0.015
cellular protein modification process GO:0006464 207 0.015
regulation of intracellular signal transduction GO:1902531 77 0.015
hormone secretion GO:0046879 2 0.015
synaptic vesicle transport GO:0048489 21 0.015
positive regulation of transcription dna templated GO:0045893 102 0.015
negative regulation of cellular biosynthetic process GO:0031327 65 0.015
macromolecule catabolic process GO:0009057 202 0.015
purine nucleotide catabolic process GO:0006195 75 0.015
neurotransmitter secretion GO:0007269 26 0.014
organelle localization GO:0051640 127 0.014
regulation of purine nucleotide metabolic process GO:1900542 37 0.014
negative regulation of cellular metabolic process GO:0031324 95 0.014
male sex differentiation GO:0046661 86 0.014
microtubule based process GO:0007017 182 0.014
response to mechanical stimulus GO:0009612 28 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 28 0.014
purine ribonucleotide catabolic process GO:0009154 75 0.014
chromosome segregation GO:0007059 180 0.014
actomyosin structure organization GO:0031032 154 0.013
hatching GO:0035188 48 0.013
vesicle localization GO:0051648 24 0.013
positive regulation of catalytic activity GO:0043085 59 0.013
purine containing compound catabolic process GO:0072523 75 0.013
nucleoside catabolic process GO:0009164 78 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.013
aromatic compound biosynthetic process GO:0019438 192 0.013
myosin filament organization GO:0031033 138 0.013
single organism intracellular transport GO:1902582 70 0.013
nervous system development GO:0007399 253 0.013
positive regulation of neurotransmitter transport GO:0051590 11 0.013
positive regulation of response to stimulus GO:0048584 55 0.013
negative regulation of cell communication GO:0010648 61 0.013
posttranscriptional gene silencing by rna GO:0035194 143 0.013
glycosyl compound catabolic process GO:1901658 79 0.013
digestive tract morphogenesis GO:0048546 76 0.013
purine ribonucleotide metabolic process GO:0009150 95 0.013
negative regulation of cell cycle GO:0045786 53 0.013
axon guidance GO:0007411 82 0.013
negative regulation of cell morphogenesis involved in differentiation GO:0010771 2 0.013
negative regulation of response to stimulus GO:0048585 73 0.013
ribonucleotide catabolic process GO:0009261 75 0.012
cell proliferation GO:0008283 116 0.012
exocytosis GO:0006887 15 0.012
establishment of cell polarity GO:0030010 46 0.012
muscle cell differentiation GO:0042692 171 0.012
negative regulation of biosynthetic process GO:0009890 65 0.012
tissue morphogenesis GO:0048729 65 0.012
guanosine containing compound catabolic process GO:1901069 48 0.012
regulation of neurotransmitter secretion GO:0046928 16 0.012
nucleoside phosphate catabolic process GO:1901292 77 0.012
purine nucleoside triphosphate catabolic process GO:0009146 72 0.012
epithelial cell proliferation GO:0050673 1 0.012
regulation of gastrulation GO:0010470 4 0.012
posttranscriptional gene silencing GO:0016441 143 0.012
cellular response to inorganic substance GO:0071241 3 0.012
positive regulation of synapse assembly GO:0051965 1 0.012
cell type specific apoptotic process GO:0097285 4 0.012
positive regulation of intracellular transport GO:0032388 2 0.012
regulation of hydrolase activity GO:0051336 45 0.012
proteolysis GO:0006508 61 0.011
cell projection morphogenesis GO:0048858 148 0.011
regulation of nucleoside metabolic process GO:0009118 37 0.011
vulval development GO:0040025 333 0.011
ribose phosphate metabolic process GO:0019693 99 0.011
organism emergence from protective structure GO:0071684 48 0.011
regulation of catabolic process GO:0009894 57 0.011
regulation of reproductive process GO:2000241 66 0.011
signal release GO:0023061 28 0.011
gene silencing by rna GO:0031047 143 0.011
regulation of organelle organization GO:0033043 164 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.011
organophosphate catabolic process GO:0046434 81 0.011
regulation of lipid metabolic process GO:0019216 4 0.011
regulation of nucleotide catabolic process GO:0030811 35 0.011
spindle organization GO:0007051 92 0.011
membrane invagination GO:0010324 98 0.011
ribonucleotide metabolic process GO:0009259 99 0.011
regulation of axon extension GO:0030516 20 0.010
synaptic vesicle localization GO:0097479 22 0.010
regulation of epithelial cell proliferation GO:0050678 1 0.010
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.010
mitotic cell cycle process GO:1903047 194 0.010
positive regulation of cellular catabolic process GO:0031331 35 0.010
positive regulation of ras gtpase activity GO:0032320 19 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.010
regulation of synaptic transmission glutamatergic GO:0051966 4 0.010
response to inorganic substance GO:0010035 50 0.010
intracellular transport GO:0046907 77 0.010
cellular macromolecule catabolic process GO:0044265 73 0.010

ptl-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
disease of anatomical entity DOID:7 0 0.015
organ system cancer DOID:0050686 0 0.013