Caenorhabditis elegans

45 known processes

unc-38 (CELE_F21F3.5)

Protein UNC-38

unc-38 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
acetate ester metabolic process GO:1900619 4 0.953
Worm
acetylcholine metabolic process GO:0008291 4 0.950
Worm
embryo development ending in birth or egg hatching GO:0009792 2992 0.688
Worm
neurotransmitter catabolic process GO:0042135 4 0.670
Worm
cell cell signaling GO:0007267 118 0.601
acetylcholine catabolic process GO:0006581 4 0.578
Worm
neurotransmitter metabolic process GO:0042133 6 0.523
Worm
locomotion GO:0040011 1634 0.449
transport GO:0006810 1093 0.409
embryo development GO:0009790 3052 0.406
Worm
synaptic transmission GO:0007268 106 0.355
cation transport GO:0006812 78 0.340
Worm
multicellular organism reproduction GO:0032504 819 0.319
regulation of striated muscle contraction GO:0006942 4 0.317
Worm
synaptic transmission cholinergic GO:0007271 21 0.300
Worm
vesicle mediated transport GO:0016192 852 0.290
Worm
ion transmembrane transport GO:0034220 91 0.283
establishment of localization GO:0051234 1171 0.277
regulation of feeding behavior GO:0060259 38 0.262
Worm
oviposition GO:0018991 364 0.257
positive regulation of striated muscle contraction GO:0045989 2 0.242
Worm
regulation of transport GO:0051049 91 0.229
Worm
system process GO:0003008 136 0.216
Worm
behavior GO:0007610 527 0.204
single organism localization GO:1902578 518 0.198
cell development GO:0048468 696 0.197
regulation of oviposition GO:0046662 43 0.189
single organism transport GO:0044765 447 0.187
regulation of response to stimulus GO:0048583 243 0.183
organic substance catabolic process GO:1901575 294 0.179
Worm
signaling GO:0023052 401 0.168
aging GO:0007568 812 0.162
Worm
determination of adult lifespan GO:0008340 812 0.162
Worm
post embryonic development GO:0009791 2152 0.159
Worm
regulation of localization GO:0032879 194 0.157
Worm
multi multicellular organism process GO:0044706 390 0.157
multicellular organismal aging GO:0010259 812 0.157
Worm
multicellular organismal reproductive process GO:0048609 815 0.157
regulation of developmental process GO:0050793 684 0.148
Worm
regulation of neurotransmitter levels GO:0001505 36 0.147
Worm
catabolic process GO:0009056 318 0.143
Worm
regulation of biological quality GO:0065008 741 0.133
Worm
organ development GO:0048513 1102 0.132
endocytosis GO:0006897 819 0.127
Worm
regulation of behavior GO:0050795 97 0.126
transmembrane transport GO:0055085 110 0.124
regulation of locomotion GO:0040012 161 0.117
Worm
regulation of developmental growth GO:0048638 389 0.117
Worm
positive regulation of multicellular organismal process GO:0051240 417 0.116
Worm
muscle contraction GO:0006936 43 0.113
Worm
growth GO:0040007 562 0.112
Worm
excretion GO:0007588 49 0.109
Worm
reproductive system development GO:0061458 850 0.108
regulation of cellular component organization GO:0051128 248 0.107
Worm
developmental growth GO:0048589 412 0.105
Worm
single organism signaling GO:0044700 401 0.101
multicellular organism growth GO:0035264 385 0.098
Worm
regulation of growth GO:0040008 409 0.096
Worm
multi organism behavior GO:0051705 389 0.093
striated muscle contraction GO:0006941 17 0.093
Worm
negative regulation of biological process GO:0048519 567 0.089
head development GO:0060322 1 0.088
macromolecule localization GO:0033036 771 0.086
regulation of pharyngeal pumping GO:0043051 36 0.084
Worm
neuromuscular synaptic transmission GO:0007274 6 0.084
pharyngeal pumping GO:0043050 58 0.084
Worm
regulation of multicellular organismal development GO:2000026 317 0.083
cellular catabolic process GO:0044248 199 0.083
Worm
organelle assembly GO:0070925 214 0.082
cellular localization GO:0051641 360 0.079
regulation of multi organism process GO:0043900 69 0.078
regulation of muscle contraction GO:0006937 20 0.076
Worm
sex differentiation GO:0007548 909 0.076
multi organism reproductive process GO:0044703 867 0.075
regulation of multicellular organism growth GO:0040014 373 0.074
Worm
regulation of multicellular organismal process GO:0051239 726 0.073
regulation of vesicle mediated transport GO:0060627 27 0.071
Worm
reproductive behavior GO:0019098 387 0.070
cation transmembrane transport GO:0098655 59 0.069
Worm
multicellular organismal reproductive behavior GO:0033057 384 0.069
protein complex subunit organization GO:0071822 280 0.066
muscle cell development GO:0055001 158 0.066
regulation of cellular metabolic process GO:0031323 305 0.066
multi organism reproductive behavior GO:0044705 387 0.065
muscle system process GO:0003012 43 0.064
Worm
cytoskeleton organization GO:0007010 339 0.063
organelle organization GO:0006996 783 0.063
eating behavior GO:0042755 59 0.062
Worm
maintenance of location GO:0051235 580 0.060
single organism reproductive process GO:0044702 1196 0.060
actin filament based process GO:0030029 191 0.058
cellular component morphogenesis GO:0032989 318 0.058
establishment of localization in cell GO:0051649 318 0.058
cell part morphogenesis GO:0032990 152 0.057
single organism catabolic process GO:0044712 129 0.056
Worm
positive regulation of metabolic process GO:0009893 187 0.056
anatomical structure formation involved in morphogenesis GO:0048646 250 0.056
lipid storage GO:0019915 565 0.055
neuron development GO:0048666 199 0.055
macromolecular complex subunit organization GO:0043933 320 0.054
actin cytoskeleton organization GO:0030036 184 0.054
cellular component biogenesis GO:0044085 297 0.053
cellular component assembly GO:0022607 293 0.053
single organism organelle organization GO:1902589 501 0.052
positive regulation of molecular function GO:0044093 61 0.052
lipid localization GO:0010876 573 0.051
cellular protein complex assembly GO:0043623 178 0.051
regulation of cell differentiation GO:0045595 81 0.050
protein metabolic process GO:0019538 422 0.050
localization of cell GO:0051674 313 0.050
gonad development GO:0008406 840 0.049
positive regulation of transcription from rna polymerase ii promoter involved in defense response to gram negative bacterium GO:1902097 4 0.045
axon development GO:0061564 163 0.045
cellular biosynthetic process GO:0044249 315 0.044
secretion by cell GO:0032940 138 0.042
body morphogenesis GO:0010171 620 0.042
regulation of metabolic process GO:0019222 478 0.042
generation of neurons GO:0048699 235 0.042
receptor mediated endocytosis GO:0006898 715 0.041
positive regulation of cellular process GO:0048522 332 0.041
striated muscle cell development GO:0055002 157 0.040
neuron differentiation GO:0030182 217 0.040
developmental process involved in reproduction GO:0003006 1165 0.038
ion transport GO:0006811 113 0.037
regulation of endocytosis GO:0030100 25 0.037
Worm
regulation of macromolecule metabolic process GO:0060255 421 0.037
protein complex assembly GO:0006461 186 0.037
cellular macromolecular complex assembly GO:0034622 184 0.036
germ cell development GO:0007281 351 0.036
muscle tissue development GO:0060537 1 0.036
phosphate containing compound metabolic process GO:0006796 232 0.036
muscle structure development GO:0061061 191 0.036
phosphorylation GO:0016310 116 0.035
skeletal muscle organ development GO:0060538 3 0.035
axon extension GO:0048675 37 0.035
apoptotic process GO:0006915 478 0.035
response to chemical GO:0042221 356 0.035
post embryonic organ development GO:0048569 336 0.034
cellular component assembly involved in morphogenesis GO:0010927 183 0.034
regulation of cellular component size GO:0032535 40 0.034
nucleobase containing compound metabolic process GO:0006139 406 0.034
regulation of nitrogen compound metabolic process GO:0051171 222 0.034
developmental growth involved in morphogenesis GO:0060560 37 0.033
cell migration GO:0016477 306 0.033
regulation of cell communication GO:0010646 176 0.033
neurotransmitter transport GO:0006836 32 0.033
regulation of phosphorus metabolic process GO:0051174 81 0.032
positive regulation of cell projection organization GO:0031346 4 0.032
reproductive structure development GO:0048608 850 0.032
organonitrogen compound metabolic process GO:1901564 151 0.032
sexual reproduction GO:0019953 546 0.031
acetylcholine transport GO:0015870 16 0.031
macromolecule modification GO:0043412 218 0.031
epithelial tube morphogenesis GO:0060562 1 0.031
signal transduction GO:0007165 317 0.031
positive regulation of phosphorus metabolic process GO:0010562 56 0.031
positive regulation of multicellular organism growth GO:0040018 352 0.031
cell projection morphogenesis GO:0048858 148 0.031
striated muscle cell differentiation GO:0051146 158 0.030
death GO:0016265 547 0.030
phosphorus metabolic process GO:0006793 232 0.030
regulation of primary metabolic process GO:0080090 292 0.029
myosin filament organization GO:0031033 138 0.029
cell cycle GO:0007049 526 0.029
macromolecular complex assembly GO:0065003 193 0.029
regulation of reproductive process GO:2000241 66 0.029
secretion GO:0046903 147 0.029
cell type specific apoptotic process GO:0097285 4 0.028
positive regulation of locomotion GO:0040017 42 0.028
regulation of acetylcholine secretion neurotransmission GO:0014056 9 0.027
cell death GO:0008219 547 0.027
acetate ester transport GO:1901374 16 0.027
cell projection organization GO:0030030 231 0.026
epithelium development GO:0060429 68 0.026
protein complex biogenesis GO:0070271 186 0.026
myosin filament assembly GO:0031034 138 0.026
carbohydrate derivative metabolic process GO:1901135 141 0.026
programmed cell death GO:0012501 500 0.026
muscle fiber development GO:0048747 2 0.026
regulation of synapse assembly GO:0051963 2 0.025
cellular protein modification process GO:0006464 207 0.025
myofibril assembly GO:0030239 154 0.025
feeding behavior GO:0007631 70 0.025
Worm
protein catabolic process GO:0030163 162 0.025
regulation of neuron differentiation GO:0045664 40 0.025
synaptic vesicle transport GO:0048489 21 0.024
cell morphogenesis GO:0000902 163 0.024
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.024
muscle cell differentiation GO:0042692 171 0.024
membrane organization GO:0061024 135 0.024
negative regulation of cellular process GO:0048523 239 0.024
neuron projection development GO:0031175 187 0.023
defecation GO:0030421 47 0.023
Worm
macromolecule catabolic process GO:0009057 202 0.023
gene expression GO:0010467 412 0.023
regulation of system process GO:0044057 27 0.023
Worm
cellular macromolecule localization GO:0070727 75 0.023
neurogenesis GO:0022008 236 0.023
single organism cellular localization GO:1902580 72 0.023
response to external stimulus GO:0009605 289 0.023
protein modification process GO:0036211 207 0.022
cellular component movement GO:0006928 388 0.022
positive regulation of growth GO:0045927 369 0.022
positive regulation of macromolecule metabolic process GO:0010604 149 0.022
macromolecule biosynthetic process GO:0009059 250 0.022
cell motility GO:0048870 313 0.021
gamete generation GO:0007276 461 0.021
regulation of neuron projection development GO:0010975 31 0.021
negative regulation of developmental process GO:0051093 227 0.020
positive regulation of neuron differentiation GO:0045666 4 0.020
organelle localization GO:0051640 127 0.020
neurotransmitter secretion GO:0007269 26 0.020
negative regulation of neurogenesis GO:0050768 4 0.020
small molecule metabolic process GO:0044281 186 0.020
transcription from rna polymerase ii promoter GO:0006366 149 0.020
taxis GO:0042330 128 0.020
purine containing compound metabolic process GO:0072521 95 0.020
nucleic acid metabolic process GO:0090304 299 0.020
positive regulation of developmental process GO:0051094 408 0.020
regulation of synaptic transmission dopaminergic GO:0032225 1 0.020
positive regulation of neurogenesis GO:0050769 4 0.020
organic substance transport GO:0071702 113 0.020
positive regulation of neuron projection development GO:0010976 4 0.019
regulation of neurogenesis GO:0050767 40 0.019
nervous system development GO:0007399 253 0.019
nitrogen compound transport GO:0071705 49 0.019
protein localization GO:0008104 205 0.019
regulation of cell projection organization GO:0031344 38 0.019
actomyosin structure organization GO:0031032 154 0.019
hermaphrodite genitalia development GO:0040035 734 0.019
protein phosphorylation GO:0006468 85 0.019
cellular protein localization GO:0034613 75 0.019
positive regulation of developmental growth GO:0048639 354 0.018
regulation of axon extension GO:0030516 20 0.018
positive regulation of protein kinase activity GO:0045860 18 0.018
organic substance biosynthetic process GO:1901576 323 0.018
regulation of cellular biosynthetic process GO:0031326 189 0.018
cellular protein metabolic process GO:0044267 279 0.018
intracellular signal transduction GO:0035556 96 0.018
cell division GO:0051301 262 0.018
rna metabolic process GO:0016070 228 0.018
regulation of neurotransmitter secretion GO:0046928 16 0.017
regulation of cellular localization GO:0060341 42 0.017
nucleotide metabolic process GO:0009117 108 0.017
small molecule biosynthetic process GO:0044283 38 0.017
striated muscle myosin thick filament assembly GO:0071688 138 0.017
microtubule based process GO:0007017 182 0.017
neuromuscular junction development GO:0007528 2 0.017
molting cycle GO:0042303 281 0.017
tissue morphogenesis GO:0048729 65 0.017
ribonucleotide metabolic process GO:0009259 99 0.017
biosynthetic process GO:0009058 323 0.017
positive regulation of cell migration GO:0030335 3 0.016
chemotaxis GO:0006935 120 0.016
nucleobase containing compound biosynthetic process GO:0034654 184 0.016
development of primary sexual characteristics GO:0045137 840 0.016
protein oligomerization GO:0051259 4 0.016
purine ribonucleotide metabolic process GO:0009150 95 0.016
multicellular organismal movement GO:0050879 2 0.016
regulation of signaling GO:0023051 172 0.015
tube development GO:0035295 126 0.015
positive regulation of cellular metabolic process GO:0031325 178 0.015
regulation of gene expression GO:0010468 366 0.015
regulation of phosphate metabolic process GO:0019220 81 0.015
regulation of extent of cell growth GO:0061387 20 0.015
sensory organ morphogenesis GO:0090596 2 0.015
cell morphogenesis involved in differentiation GO:0000904 112 0.015
regulation of macromolecule biosynthetic process GO:0010556 189 0.015
positive regulation of transport GO:0051050 32 0.015
regulation of neurotransmitter transport GO:0051588 16 0.015
nucleobase containing small molecule metabolic process GO:0055086 115 0.015
negative regulation of multicellular organismal process GO:0051241 236 0.015
rna localization GO:0006403 3 0.015
ribose phosphate metabolic process GO:0019693 99 0.015
cell growth GO:0016049 44 0.015
developmental cell growth GO:0048588 39 0.015
positive regulation of cell communication GO:0010647 69 0.014
monocarboxylic acid biosynthetic process GO:0072330 13 0.014
organophosphate metabolic process GO:0019637 125 0.014
establishment of organelle localization GO:0051656 123 0.014
nucleoside phosphate metabolic process GO:0006753 108 0.014
heterocycle biosynthetic process GO:0018130 187 0.014
regulation of muscle system process GO:0090257 20 0.014
Worm
defense response GO:0006952 296 0.014
nucleic acid templated transcription GO:0097659 169 0.014
intracellular transport GO:0046907 77 0.014
negative regulation of metabolic process GO:0009892 240 0.014
regulation of signal transduction GO:0009966 135 0.014
immune response GO:0006955 192 0.014
embryonic morphogenesis GO:0048598 152 0.014
regulation of biosynthetic process GO:0009889 189 0.014
ribonucleoside metabolic process GO:0009119 98 0.013
neuron projection extension GO:1990138 37 0.013
rna interference GO:0016246 137 0.013
ribonucleoside triphosphate catabolic process GO:0009203 72 0.013
negative regulation of gene expression GO:0010629 217 0.013
regulation of anatomical structure morphogenesis GO:0022603 51 0.013
posttranscriptional gene silencing GO:0016441 143 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
purine nucleotide metabolic process GO:0006163 95 0.013
regulation of anatomical structure size GO:0090066 46 0.013
negative regulation of macromolecule metabolic process GO:0010605 229 0.013
neuron projection morphogenesis GO:0048812 114 0.013
small gtpase mediated signal transduction GO:0007264 32 0.013
regulation of cell size GO:0008361 30 0.013
cell cycle process GO:0022402 482 0.013
establishment of vesicle localization GO:0051650 23 0.013
organic acid biosynthetic process GO:0016053 21 0.013
cell recognition GO:0008037 85 0.013
posttranscriptional gene silencing by rna GO:0035194 143 0.013
regulation of organelle organization GO:0033043 164 0.013
positive regulation of ion transport GO:0043270 10 0.012
axonal fasciculation GO:0007413 79 0.012
digestive tract morphogenesis GO:0048546 76 0.012
regulation of cellular catabolic process GO:0031329 51 0.012
negative regulation of axon extension GO:0030517 2 0.012
regulation of cellular component movement GO:0051270 62 0.012
regulation of cell motility GO:2000145 57 0.012
organelle fission GO:0048285 363 0.012
tube morphogenesis GO:0035239 79 0.012
regulation of cell projection assembly GO:0060491 3 0.012
regulation of catalytic activity GO:0050790 78 0.012
synapse organization GO:0050808 24 0.012
glycosyl compound metabolic process GO:1901657 100 0.012
positive regulation of response to stimulus GO:0048584 55 0.012
defense response to other organism GO:0098542 100 0.012
positive regulation of amine transport GO:0051954 8 0.012
acetylcholine secretion GO:0061526 11 0.012
aromatic compound catabolic process GO:0019439 116 0.012
motor neuron axon guidance GO:0008045 13 0.012
neuron neuron synaptic transmission GO:0007270 22 0.012
cell surface receptor signaling pathway GO:0007166 149 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.011
calcium ion transport GO:0006816 16 0.011
ras protein signal transduction GO:0007265 31 0.011
divalent inorganic cation transport GO:0072511 17 0.011
gene silencing by rna GO:0031047 143 0.011
organic cyclic compound catabolic process GO:1901361 119 0.011
establishment of protein localization to membrane GO:0090150 3 0.011
female gamete generation GO:0007292 254 0.011
actin filament based movement GO:0030048 4 0.011
organic acid metabolic process GO:0006082 47 0.011
tissue development GO:0009888 112 0.011
male sex differentiation GO:0046661 86 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.011
innate immune response GO:0045087 190 0.011
regulation of cellular protein metabolic process GO:0032268 75 0.011
positive regulation of protein transport GO:0051222 4 0.011
regulation of intracellular signal transduction GO:1902531 77 0.011
organic cyclic compound biosynthetic process GO:1901362 195 0.011
oxoacid metabolic process GO:0043436 47 0.011
regulation of nervous system development GO:0051960 41 0.011
positive regulation of jnk cascade GO:0046330 3 0.011
cellular amine metabolic process GO:0044106 15 0.011
single organism behavior GO:0044708 83 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.011
regulation of synaptic transmission GO:0050804 34 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.011
genitalia development GO:0048806 741 0.011
single organism membrane organization GO:0044802 35 0.011
oogenesis GO:0048477 229 0.011
regulation of cell morphogenesis GO:0022604 40 0.011
activation of protein kinase activity GO:0032147 11 0.010
synaptic vesicle localization GO:0097479 22 0.010
canonical wnt signaling pathway GO:0060070 3 0.010
membrane depolarization GO:0051899 1 0.010
synaptic vesicle endocytosis GO:0048488 3 0.010
cell proliferation GO:0008283 116 0.010
response to wounding GO:0009611 4 0.010
cellular nitrogen compound biosynthetic process GO:0044271 192 0.010
regulation of nucleic acid templated transcription GO:1903506 165 0.010

unc-38 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.018