Caenorhabditis elegans

70 known processes

unc-2 (CELE_T02C5.5)

Protein UNC-2

unc-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of localization GO:0051234 1171 0.329
Mouse Rat Worm Fly
multi organism reproductive process GO:0044703 867 0.321
Worm Fly
sexual reproduction GO:0019953 546 0.281
Fly
embryo development GO:0009790 3052 0.258
multicellular organismal reproductive process GO:0048609 815 0.231
Worm Fly
post embryonic development GO:0009791 2152 0.203
vesicle mediated transport GO:0016192 852 0.194
Mouse Fly
locomotion GO:0040011 1634 0.184
Mouse
neurotransmitter transport GO:0006836 32 0.180
Mouse Rat Fly
reproductive behavior GO:0019098 387 0.169
Worm Fly
developmental process involved in reproduction GO:0003006 1165 0.169
Worm
transport GO:0006810 1093 0.162
Mouse Rat Worm Fly
multicellular organism reproduction GO:0032504 819 0.161
Worm Fly
multi organism reproductive behavior GO:0044705 387 0.158
Worm Fly
body morphogenesis GO:0010171 620 0.157
g protein coupled receptor signaling pathway GO:0007186 46 0.153
Mouse
single organism signaling GO:0044700 401 0.141
multi multicellular organism process GO:0044706 390 0.140
Worm Fly
feeding behavior GO:0007631 70 0.133
Worm
embryo development ending in birth or egg hatching GO:0009792 2992 0.126
behavior GO:0007610 527 0.125
endocytosis GO:0006897 819 0.125
nucleoside triphosphate catabolic process GO:0009143 72 0.124
regulation of biological quality GO:0065008 741 0.113
oviposition GO:0018991 364 0.113
Worm
macromolecule localization GO:0033036 771 0.112
Mouse
multicellular organismal reproductive behavior GO:0033057 384 0.111
Worm Fly
purine nucleotide catabolic process GO:0006195 75 0.108
establishment of localization in cell GO:0051649 318 0.106
Mouse Rat Fly
death GO:0016265 547 0.104
Mouse
hermaphrodite genitalia development GO:0040035 734 0.099
Worm
synaptic transmission GO:0007268 106 0.099
organelle organization GO:0006996 783 0.096
microtubule based process GO:0007017 182 0.095
regulation of response to stimulus GO:0048583 243 0.093
single organism reproductive process GO:0044702 1196 0.091
Worm
cell cell signaling GO:0007267 118 0.089
glycosyl compound metabolic process GO:1901657 100 0.088
cell development GO:0048468 696 0.086
Mouse
single organism organelle organization GO:1902589 501 0.086
regulation of multicellular organismal process GO:0051239 726 0.086
Mouse Fly
organelle localization GO:0051640 127 0.083
ribonucleoside metabolic process GO:0009119 98 0.081
organonitrogen compound catabolic process GO:1901565 90 0.080
ribonucleoside catabolic process GO:0042454 77 0.080
multi organism behavior GO:0051705 389 0.079
Worm Fly
negative regulation of biological process GO:0048519 567 0.078
reproductive structure development GO:0048608 850 0.077
Worm
single organism localization GO:1902578 518 0.076
Mouse Rat Worm Fly
aromatic compound catabolic process GO:0019439 116 0.076
purine ribonucleotide catabolic process GO:0009154 75 0.075
purine containing compound catabolic process GO:0072523 75 0.075
protein complex subunit organization GO:0071822 280 0.074
maintenance of location GO:0051235 580 0.073
lipid localization GO:0010876 573 0.072
signaling GO:0023052 401 0.072
single organism transport GO:0044765 447 0.071
Mouse Rat Worm Fly
receptor mediated endocytosis GO:0006898 715 0.071
lipid storage GO:0019915 565 0.071
purine nucleoside triphosphate catabolic process GO:0009146 72 0.070
organic cyclic compound catabolic process GO:1901361 119 0.070
growth GO:0040007 562 0.066
Mouse Fly
catabolic process GO:0009056 318 0.065
establishment of organelle localization GO:0051656 123 0.065
cytoskeleton organization GO:0007010 339 0.065
organophosphate catabolic process GO:0046434 81 0.064
immune response GO:0006955 192 0.063
ribonucleotide catabolic process GO:0009261 75 0.063
regulation of locomotion GO:0040012 161 0.062
cellular localization GO:0051641 360 0.062
Mouse Rat Fly
ribonucleoside triphosphate metabolic process GO:0009199 87 0.062
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.061
regulation of neurotransmitter levels GO:0001505 36 0.061
carbohydrate derivative metabolic process GO:1901135 141 0.061
nucleoside catabolic process GO:0009164 78 0.061
nucleobase containing compound catabolic process GO:0034655 114 0.061
aging GO:0007568 812 0.060
synaptic vesicle localization GO:0097479 22 0.060
purine ribonucleoside catabolic process GO:0046130 75 0.059
nucleoside phosphate catabolic process GO:1901292 77 0.058
carbohydrate derivative catabolic process GO:1901136 82 0.058
cellular protein complex assembly GO:0043623 178 0.058
cell part morphogenesis GO:0032990 152 0.058
Mouse
regulation of cell communication GO:0010646 176 0.057
reproductive system development GO:0061458 850 0.057
Worm
taxis GO:0042330 128 0.057
phosphorus metabolic process GO:0006793 232 0.055
nucleoside triphosphate metabolic process GO:0009141 87 0.055
cell migration GO:0016477 306 0.053
synaptic vesicle transport GO:0048489 21 0.051
cellular component morphogenesis GO:0032989 318 0.051
Mouse
purine ribonucleoside metabolic process GO:0046128 92 0.051
programmed cell death GO:0012501 500 0.051
Mouse
positive regulation of synaptic transmission GO:0050806 24 0.051
Rat
single organism behavior GO:0044708 83 0.051
Mouse Fly
nucleobase containing compound metabolic process GO:0006139 406 0.050
nucleotide catabolic process GO:0009166 77 0.050
protein catabolic process GO:0030163 162 0.050
mating GO:0007618 34 0.049
Fly
purine nucleoside triphosphate metabolic process GO:0009144 87 0.049
purine nucleoside catabolic process GO:0006152 75 0.049
cellular component biogenesis GO:0044085 297 0.048
Mouse Fly
small molecule metabolic process GO:0044281 186 0.048
Mouse
nucleotide metabolic process GO:0009117 108 0.048
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.047
cellular component assembly GO:0022607 293 0.047
Mouse Fly
innate immune response GO:0045087 190 0.046
purine nucleotide metabolic process GO:0006163 95 0.046
regulation of multicellular organismal development GO:2000026 317 0.046
Mouse Fly
purine ribonucleotide metabolic process GO:0009150 95 0.046
phosphate containing compound metabolic process GO:0006796 232 0.046
heterocycle catabolic process GO:0046700 119 0.046
cellular macromolecular complex assembly GO:0034622 184 0.046
neuron projection morphogenesis GO:0048812 114 0.045
Mouse
organic substance catabolic process GO:1901575 294 0.045
developmental growth GO:0048589 412 0.045
Fly
response to external stimulus GO:0009605 289 0.043
gamete generation GO:0007276 461 0.043
sex differentiation GO:0007548 909 0.043
Worm
cellular component movement GO:0006928 388 0.043
Mouse
signal transduction GO:0007165 317 0.042
organelle assembly GO:0070925 214 0.042
axon development GO:0061564 163 0.041
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 72 0.041
cell death GO:0008219 547 0.040
Mouse
positive regulation of nucleoside metabolic process GO:0045979 28 0.040
regulation of growth GO:0040008 409 0.039
Fly
pattern specification process GO:0007389 59 0.039
regulation of developmental process GO:0050793 684 0.039
Mouse Fly
protein localization GO:0008104 205 0.038
Mouse
defense response GO:0006952 296 0.038
Mouse
development of primary sexual characteristics GO:0045137 840 0.038
Worm
regulation of purine nucleotide catabolic process GO:0033121 35 0.038
nucleoside metabolic process GO:0009116 99 0.037
gonad development GO:0008406 840 0.037
Worm
cell cycle GO:0007049 526 0.037
guanosine containing compound catabolic process GO:1901069 48 0.037
multicellular organismal aging GO:0010259 812 0.036
purine nucleoside metabolic process GO:0042278 92 0.036
multicellular organism growth GO:0035264 385 0.036
regulation of synaptic transmission glutamatergic GO:0051966 4 0.036
macromolecule catabolic process GO:0009057 202 0.035
purine containing compound metabolic process GO:0072521 95 0.035
macromolecular complex subunit organization GO:0043933 320 0.035
nucleoside phosphate metabolic process GO:0006753 108 0.035
regulation of developmental growth GO:0048638 389 0.034
Fly
membrane depolarization GO:0051899 1 0.034
Mouse
negative regulation of multicellular organismal process GO:0051241 236 0.034
regulation of phosphate metabolic process GO:0019220 81 0.034
regulation of cell morphogenesis GO:0022604 40 0.034
Mouse
cellular nitrogen compound catabolic process GO:0044270 119 0.034
pharyngeal pumping GO:0043050 58 0.034
Worm
regulation of feeding behavior GO:0060259 38 0.033
Worm
organ development GO:0048513 1102 0.033
Mouse Worm
protein complex assembly GO:0006461 186 0.033
positive regulation of growth GO:0045927 369 0.032
Fly
nucleobase containing small molecule metabolic process GO:0055086 115 0.032
regulation of behavior GO:0050795 97 0.032
Worm
regulation of multicellular organism growth GO:0040014 373 0.032
cellular component assembly involved in morphogenesis GO:0010927 183 0.031
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.031
membrane organization GO:0061024 135 0.031
Mouse
establishment of vesicle localization GO:0051650 23 0.031
axonogenesis GO:0007409 102 0.031
Mouse
ribonucleotide metabolic process GO:0009259 99 0.031
cell morphogenesis involved in differentiation GO:0000904 112 0.031
Mouse
guanosine containing compound metabolic process GO:1901068 49 0.031
actomyosin structure organization GO:0031032 154 0.031
regulation of signaling GO:0023051 172 0.031
system process GO:0003008 136 0.031
Mouse Rat Fly
secretion by cell GO:0032940 138 0.031
Mouse Rat Fly
striated muscle myosin thick filament assembly GO:0071688 138 0.030
organophosphate metabolic process GO:0019637 125 0.030
gtp metabolic process GO:0046039 46 0.030
actin cytoskeleton organization GO:0030036 184 0.030
anatomical structure formation involved in morphogenesis GO:0048646 250 0.030
Mouse
cell cycle process GO:0022402 482 0.030
regulation of localization GO:0032879 194 0.029
Mouse Rat Worm Fly
regulation of nucleoside metabolic process GO:0009118 37 0.029
glycosyl compound catabolic process GO:1901658 79 0.029
determination of adult lifespan GO:0008340 812 0.029
vesicle localization GO:0051648 24 0.028
organonitrogen compound metabolic process GO:1901564 151 0.028
Mouse
head development GO:0060322 1 0.028
Mouse
macromolecular complex assembly GO:0065003 193 0.027
protein metabolic process GO:0019538 422 0.027
phagocytosis GO:0006909 115 0.027
generation of neurons GO:0048699 235 0.026
Mouse
female gamete generation GO:0007292 254 0.026
regulation of metabolic process GO:0019222 478 0.026
Mouse
muscle structure development GO:0061061 191 0.026
germ cell development GO:0007281 351 0.025
actin filament based process GO:0030029 191 0.025
eating behavior GO:0042755 59 0.025
Worm
positive regulation of developmental growth GO:0048639 354 0.025
Fly
neurogenesis GO:0022008 236 0.024
Mouse
regulation of nervous system development GO:0051960 41 0.024
Mouse Fly
single organism catabolic process GO:0044712 129 0.024
turning behavior involved in mating GO:0034607 12 0.024
genitalia development GO:0048806 741 0.024
Worm
regulation of gene expression GO:0010468 366 0.024
neurological system process GO:0050877 53 0.024
Mouse Rat Fly
myosin filament assembly GO:0031034 138 0.024
gtp catabolic process GO:0006184 46 0.023
cell projection morphogenesis GO:0048858 148 0.023
Mouse
protein complex biogenesis GO:0070271 186 0.023
myosin filament organization GO:0031033 138 0.023
neuron neuron synaptic transmission GO:0007270 22 0.023
Mouse
regulation of phosphorus metabolic process GO:0051174 81 0.023
intracellular signal transduction GO:0035556 96 0.023
regulation of synaptic transmission GO:0050804 34 0.022
Mouse Rat Fly
memory GO:0007613 3 0.022
regulation of nucleotide catabolic process GO:0030811 35 0.022
mating behavior GO:0007617 32 0.022
Fly
regulation of purine nucleotide metabolic process GO:1900542 37 0.022
positive regulation of multicellular organism growth GO:0040018 352 0.022
secretion GO:0046903 147 0.022
Mouse Rat Fly
striated muscle cell development GO:0055002 157 0.021
neuromuscular junction development GO:0007528 2 0.021
Fly
regulation of cellular component organization GO:0051128 248 0.021
Mouse Fly
embryonic morphogenesis GO:0048598 152 0.021
molting cycle GO:0042303 281 0.021
positive regulation of signaling GO:0023056 66 0.021
Rat
regulation of transport GO:0051049 91 0.021
Mouse Rat Worm Fly
cellular catabolic process GO:0044248 199 0.021
response to wounding GO:0009611 4 0.020
ion transmembrane transport GO:0034220 91 0.020
Mouse Rat Worm Fly
myofibril assembly GO:0030239 154 0.020
positive regulation of gtpase activity GO:0043547 28 0.020
cell division GO:0051301 262 0.020
cell morphogenesis GO:0000902 163 0.020
Mouse
synaptic vesicle recycling GO:0036465 3 0.020
membrane invagination GO:0010324 98 0.020
neuron projection development GO:0031175 187 0.020
Mouse
tissue development GO:0009888 112 0.020
positive regulation of multicellular organismal process GO:0051240 417 0.019
Fly
post embryonic organ development GO:0048569 336 0.019
single organism cellular localization GO:1902580 72 0.019
Mouse
apoptotic process GO:0006915 478 0.019
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.019
Mouse
cellular biosynthetic process GO:0044249 315 0.019
Mouse
long term memory GO:0007616 2 0.019
learning or memory GO:0007611 27 0.018
Mouse
vulval development GO:0040025 333 0.018
cell motility GO:0048870 313 0.018
Mouse
apoptotic cell clearance GO:0043277 111 0.018
rna metabolic process GO:0016070 228 0.018
neuron recognition GO:0008038 83 0.018
establishment of synaptic vesicle localization GO:0097480 21 0.018
collagen and cuticulin based cuticle development GO:0040002 99 0.018
cuticle development GO:0042335 100 0.018
engulfment of apoptotic cell GO:0043652 94 0.017
oogenesis GO:0048477 229 0.017
chemotaxis GO:0006935 120 0.017
negative regulation of developmental process GO:0051093 227 0.017
neuron differentiation GO:0030182 217 0.017
Mouse
regulation of cytoskeleton organization GO:0051493 41 0.017
ion transport GO:0006811 113 0.017
Mouse Rat Worm Fly
organic substance transport GO:0071702 113 0.017
Mouse
regulation of nucleotide metabolic process GO:0006140 37 0.017
protein modification process GO:0036211 207 0.017
response to biotic stimulus GO:0009607 101 0.017
positive regulation of developmental process GO:0051094 408 0.016
Fly
regulation of macromolecule metabolic process GO:0060255 421 0.016
regulation of synaptic plasticity GO:0048167 1 0.016
positive regulation of cellular process GO:0048522 332 0.016
Rat Fly
cellular protein metabolic process GO:0044267 279 0.016
regulation of secretion GO:0051046 29 0.016
Mouse Rat Fly
male mating behavior GO:0060179 26 0.016
Fly
rna localization GO:0006403 3 0.016
phagocytosis engulfment GO:0006911 98 0.016
response to endoplasmic reticulum stress GO:0034976 71 0.016
signal release GO:0023061 28 0.016
Mouse Rat Fly
regulation of neurotransmitter transport GO:0051588 16 0.016
Mouse Rat Fly
cell recognition GO:0008037 85 0.016
developmental growth involved in morphogenesis GO:0060560 37 0.015
regulation of cellular metabolic process GO:0031323 305 0.015
Mouse
canonical wnt signaling pathway GO:0060070 3 0.015
nitrogen compound transport GO:0071705 49 0.015
Mouse
regulation of synapse assembly GO:0051963 2 0.015
Fly
response to chemical GO:0042221 356 0.015
regulation of gtp catabolic process GO:0033124 32 0.015
inductive cell migration GO:0040039 145 0.015
nucleic acid metabolic process GO:0090304 299 0.015
mitotic cell cycle process GO:1903047 194 0.015
cognition GO:0050890 27 0.015
Mouse
synaptic vesicle endocytosis GO:0048488 3 0.015
positive regulation of gtp catabolic process GO:0033126 28 0.015
sensory perception GO:0007600 27 0.015
Mouse Rat Fly
turning behavior GO:0035178 12 0.015
positive regulation of neurogenesis GO:0050769 4 0.014
cellular protein modification process GO:0006464 207 0.014
macromolecule modification GO:0043412 218 0.014
positive regulation of neuron differentiation GO:0045666 4 0.014
small gtpase mediated signal transduction GO:0007264 32 0.014
response to abiotic stimulus GO:0009628 152 0.014
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.014
organic acid metabolic process GO:0006082 47 0.014
Mouse
localization of cell GO:0051674 313 0.014
Mouse
hormone transport GO:0009914 2 0.014
Mouse
establishment of mitotic spindle localization GO:0040001 41 0.014
developmental cell growth GO:0048588 39 0.014
negative regulation of gene expression GO:0010629 217 0.014
biosynthetic process GO:0009058 323 0.014
Mouse
regulation of post embryonic development GO:0048580 260 0.014
axon guidance GO:0007411 82 0.013
regulation of exocytosis GO:0017157 1 0.013
Mouse
defense response to other organism GO:0098542 100 0.013
organic substance biosynthetic process GO:1901576 323 0.013
cation transport GO:0006812 78 0.013
Mouse Rat Worm Fly
regulation of neuron projection development GO:0010975 31 0.013
Mouse
positive regulation of molecular function GO:0044093 61 0.013
establishment of spindle localization GO:0051293 51 0.013
response to other organism GO:0051707 101 0.013
dauer larval development GO:0040024 92 0.013
positive regulation of phosphate metabolic process GO:0045937 56 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 28 0.013
regulation of nitrogen compound metabolic process GO:0051171 222 0.013
neuron development GO:0048666 199 0.013
Mouse
protein oligomerization GO:0051259 4 0.013
regulation of cell development GO:0060284 49 0.013
Mouse
regulation of vesicle mediated transport GO:0060627 27 0.012
Mouse
transmembrane transport GO:0055085 110 0.012
Mouse Rat Worm Fly
establishment of nucleus localization GO:0040023 55 0.012
establishment or maintenance of cell polarity GO:0007163 63 0.012
establishment of cell polarity GO:0030010 46 0.012
positive regulation of secretion by cell GO:1903532 14 0.012
Rat
regulation of gtpase activity GO:0043087 30 0.012
positive regulation of nucleotide catabolic process GO:0030813 28 0.012
ribose phosphate metabolic process GO:0019693 99 0.012
positive regulation of neurotransmitter transport GO:0051590 11 0.012
Rat
muscle cell development GO:0055001 158 0.012
tube development GO:0035295 126 0.012
posttranscriptional regulation of gene expression GO:0010608 166 0.012
regulation of catalytic activity GO:0050790 78 0.011
metal ion transport GO:0030001 49 0.011
Mouse Rat Worm Fly
regulation of molecular function GO:0065009 89 0.011
carboxylic acid metabolic process GO:0019752 34 0.011
Mouse
oxoacid metabolic process GO:0043436 47 0.011
Mouse
regulation of cell differentiation GO:0045595 81 0.011
Mouse
cellular macromolecule biosynthetic process GO:0034645 247 0.011
intracellular transport GO:0046907 77 0.011
regulation of protein stability GO:0031647 3 0.011
establishment of protein localization to membrane GO:0090150 3 0.011
amine metabolic process GO:0009308 15 0.011
regulation of cell division GO:0051302 142 0.011
male sex differentiation GO:0046661 86 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.011
cell fate commitment GO:0045165 139 0.011
regulation of g protein coupled receptor protein signaling pathway GO:0008277 4 0.011
regulation of signal transduction GO:0009966 135 0.011
ras protein signal transduction GO:0007265 31 0.011
regulation of cell cycle process GO:0010564 145 0.011
tissue morphogenesis GO:0048729 65 0.011
epithelial tube morphogenesis GO:0060562 1 0.011
single organism intracellular transport GO:1902582 70 0.011
regulation of actin filament based process GO:0032970 22 0.011
axon extension GO:0048675 37 0.011
regulation of pharyngeal pumping GO:0043051 36 0.011
Worm
transcription dna templated GO:0006351 168 0.010
spindle localization GO:0051653 51 0.010
nucleus localization GO:0051647 55 0.010
regulation of cellular localization GO:0060341 42 0.010
Mouse Rat Fly
regulation of vulval development GO:0040028 248 0.010
inorganic ion transmembrane transport GO:0098660 54 0.010
Mouse Rat Worm Fly
positive regulation of hydrolase activity GO:0051345 38 0.010
regulation of cellular biosynthetic process GO:0031326 189 0.010
Mouse

unc-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.011