Caenorhabditis elegans

23 known processes

lin-48 (CELE_F34D10.5)

Protein LIN-48

lin-48 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of metabolic process GO:0009893 187 0.509
Mouse Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.392
Mouse Fly
neuron projection development GO:0031175 187 0.307
regulation of response to stimulus GO:0048583 243 0.278
regulation of nitrogen compound metabolic process GO:0051171 222 0.244
Mouse Fly
regulation of primary metabolic process GO:0080090 292 0.208
Mouse Fly
sex differentiation GO:0007548 909 0.172
neuron development GO:0048666 199 0.167
head development GO:0060322 1 0.164
reproductive structure development GO:0048608 850 0.161
Mouse
positive regulation of macromolecule metabolic process GO:0010604 149 0.160
Mouse Fly
single organism reproductive process GO:0044702 1196 0.158
Mouse
regulation of cellular biosynthetic process GO:0031326 189 0.151
Mouse Fly
gonad development GO:0008406 840 0.149
positive regulation of cellular process GO:0048522 332 0.149
Mouse Fly
regulation of metabolic process GO:0019222 478 0.146
Mouse Fly
cellular macromolecule biosynthetic process GO:0034645 247 0.133
Mouse Fly
regulation of cellular metabolic process GO:0031323 305 0.130
Mouse Fly
reproductive system development GO:0061458 850 0.127
Mouse
embryo development GO:0009790 3052 0.117
Mouse
regulation of macromolecule metabolic process GO:0060255 421 0.116
Mouse Fly
organ development GO:0048513 1102 0.115
Mouse Fly
development of primary sexual characteristics GO:0045137 840 0.111
developmental process involved in reproduction GO:0003006 1165 0.104
regulation of signal transduction GO:0009966 135 0.103
cell projection organization GO:0030030 231 0.101
Fly
negative regulation of cellular process GO:0048523 239 0.092
Mouse Fly
regulation of biological quality GO:0065008 741 0.091
Fly
regulation of localization GO:0032879 194 0.091
hermaphrodite genitalia development GO:0040035 734 0.090
regulation of developmental process GO:0050793 684 0.089
Mouse Fly
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.087
Mouse Fly
genitalia development GO:0048806 741 0.086
post embryonic organ development GO:0048569 336 0.085
Fly
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.081
axon development GO:0061564 163 0.080
regulation of multicellular organismal process GO:0051239 726 0.078
Mouse
positive regulation of cellular metabolic process GO:0031325 178 0.077
Mouse Fly
macromolecule localization GO:0033036 771 0.075
negative regulation of biological process GO:0048519 567 0.072
Mouse Fly
lipid localization GO:0010876 573 0.070
negative regulation of biosynthetic process GO:0009890 65 0.070
Mouse Fly
cell fate commitment GO:0045165 139 0.070
biosynthetic process GO:0009058 323 0.067
Mouse Fly
determination of adult lifespan GO:0008340 812 0.067
maintenance of location GO:0051235 580 0.066
behavior GO:0007610 527 0.066
Fly
multicellular organismal aging GO:0010259 812 0.065
aging GO:0007568 812 0.065
positive regulation of multicellular organismal process GO:0051240 417 0.064
neuron differentiation GO:0030182 217 0.064
Fly
cellular biosynthetic process GO:0044249 315 0.063
Mouse Fly
catabolic process GO:0009056 318 0.062
body morphogenesis GO:0010171 620 0.062
response to other organism GO:0051707 101 0.062
nucleobase containing compound metabolic process GO:0006139 406 0.060
Mouse Fly
dauer larval development GO:0040024 92 0.060
regulation of nematode larval development GO:0061062 260 0.058
locomotion GO:0040011 1634 0.057
Mouse
lipid storage GO:0019915 565 0.057
regulation of multicellular organismal development GO:2000026 317 0.057
Mouse
generation of neurons GO:0048699 235 0.057
Fly
regulation of cell communication GO:0010646 176 0.056
gene expression GO:0010467 412 0.056
Mouse Fly
multi organism behavior GO:0051705 389 0.055
signaling GO:0023052 401 0.054
multicellular organism reproduction GO:0032504 819 0.054
Mouse
embryo development ending in birth or egg hatching GO:0009792 2992 0.053
Mouse
positive regulation of catalytic activity GO:0043085 59 0.052
vulval development GO:0040025 333 0.052
rho protein signal transduction GO:0007266 2 0.052
guanosine containing compound catabolic process GO:1901069 48 0.052
transport GO:0006810 1093 0.052
neurogenesis GO:0022008 236 0.050
Fly
single organism signaling GO:0044700 401 0.049
digestive system development GO:0055123 122 0.049
oviposition GO:0018991 364 0.048
regulation of cellular component organization GO:0051128 248 0.047
Mouse Fly
cellular component movement GO:0006928 388 0.047
Mouse
tube development GO:0035295 126 0.047
multi organism reproductive process GO:0044703 867 0.046
Mouse
defense response GO:0006952 296 0.046
cell morphogenesis GO:0000902 163 0.045
Mouse Fly
positive regulation of gtp catabolic process GO:0033126 28 0.045
cell death GO:0008219 547 0.045
organic substance catabolic process GO:1901575 294 0.045
negative regulation of metabolic process GO:0009892 240 0.044
Mouse Fly
positive regulation of cellular catabolic process GO:0031331 35 0.044
cellular component morphogenesis GO:0032989 318 0.043
Mouse Fly
positive regulation of gene expression GO:0010628 112 0.043
Mouse Fly
regulation of biosynthetic process GO:0009889 189 0.043
Mouse Fly
post embryonic development GO:0009791 2152 0.043
Fly
organonitrogen compound metabolic process GO:1901564 151 0.042
growth GO:0040007 562 0.042
positive regulation of biosynthetic process GO:0009891 109 0.042
Mouse Fly
reproductive behavior GO:0019098 387 0.041
regulation of neuron differentiation GO:0045664 40 0.040
digestive tract development GO:0048565 122 0.039
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.039
Mouse Fly
cell development GO:0048468 696 0.039
Mouse
apoptotic process GO:0006915 478 0.039
negative regulation of cellular biosynthetic process GO:0031327 65 0.038
Mouse Fly
programmed cell death GO:0012501 500 0.038
heterocycle biosynthetic process GO:0018130 187 0.038
Mouse Fly
endocytosis GO:0006897 819 0.038
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.038
Mouse Fly
regulation of rna metabolic process GO:0051252 173 0.037
Mouse Fly
vesicle mediated transport GO:0016192 852 0.037
macromolecule catabolic process GO:0009057 202 0.037
ribonucleoside metabolic process GO:0009119 98 0.036
signal transduction GO:0007165 317 0.036
epithelial tube morphogenesis GO:0060562 1 0.036
Mouse
regulation of cell fate specification GO:0042659 22 0.035
protein complex assembly GO:0006461 186 0.035
transcription dna templated GO:0006351 168 0.035
Mouse Fly
neuron recognition GO:0008038 83 0.035
regulation of cell differentiation GO:0045595 81 0.035
Mouse
neuron projection morphogenesis GO:0048812 114 0.035
positive regulation of developmental process GO:0051094 408 0.035
ribonucleotide metabolic process GO:0009259 99 0.035
positive regulation of nucleic acid templated transcription GO:1903508 102 0.035
Mouse Fly
axonogenesis GO:0007409 102 0.034
macromolecule biosynthetic process GO:0009059 250 0.034
Mouse Fly
positive regulation of nucleoside metabolic process GO:0045979 28 0.034
negative regulation of cell communication GO:0010648 61 0.033
purine nucleoside catabolic process GO:0006152 75 0.033
small molecule metabolic process GO:0044281 186 0.032
ras protein signal transduction GO:0007265 31 0.032
organic cyclic compound catabolic process GO:1901361 119 0.032
aromatic compound biosynthetic process GO:0019438 192 0.032
Mouse Fly
purine ribonucleotide metabolic process GO:0009150 95 0.032
nucleic acid metabolic process GO:0090304 299 0.032
Mouse Fly
positive regulation of gtpase activity GO:0043547 28 0.031
gtp metabolic process GO:0046039 46 0.031
secretion GO:0046903 147 0.030
ribonucleoside catabolic process GO:0042454 77 0.030
regulation of signaling GO:0023051 172 0.030
negative regulation of response to stimulus GO:0048585 73 0.030
positive regulation of growth GO:0045927 369 0.029
protein metabolic process GO:0019538 422 0.029
multicellular organismal reproductive process GO:0048609 815 0.029
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 192 0.028
Mouse Fly
regulation of rna biosynthetic process GO:2001141 165 0.028
Mouse Fly
rna metabolic process GO:0016070 228 0.028
Mouse Fly
regulation of gene expression GO:0010468 366 0.028
Mouse Fly
positive regulation of purine nucleotide metabolic process GO:1900544 28 0.027
aromatic compound catabolic process GO:0019439 116 0.027
positive regulation of neuron differentiation GO:0045666 4 0.027
positive regulation of neurogenesis GO:0050769 4 0.027
cellular protein complex assembly GO:0043623 178 0.027
establishment of localization GO:0051234 1171 0.027
multicellular organism growth GO:0035264 385 0.027
receptor mediated endocytosis GO:0006898 715 0.027
organic cyclic compound biosynthetic process GO:1901362 195 0.026
Mouse Fly
guanosine containing compound metabolic process GO:1901068 49 0.026
single organism localization GO:1902578 518 0.026
membrane depolarization GO:0051899 1 0.026
response to chemical GO:0042221 356 0.026
single organism transport GO:0044765 447 0.026
cellular component biogenesis GO:0044085 297 0.025
regulation of cell morphogenesis GO:0022604 40 0.025
Mouse Fly
protein complex subunit organization GO:0071822 280 0.025
regulation of catabolic process GO:0009894 57 0.025
multi organism reproductive behavior GO:0044705 387 0.025
regulation of purine nucleotide catabolic process GO:0033121 35 0.025
regulation of nucleotide catabolic process GO:0030811 35 0.025
response to external stimulus GO:0009605 289 0.025
regulation of nervous system development GO:0051960 41 0.024
regulation of multicellular organism growth GO:0040014 373 0.024
multicellular organismal reproductive behavior GO:0033057 384 0.024
positive regulation of nucleotide metabolic process GO:0045981 28 0.024
regulation of purine nucleotide metabolic process GO:1900542 37 0.024
nervous system development GO:0007399 253 0.024
Mouse Fly
protein complex biogenesis GO:0070271 186 0.024
regulation of ras gtpase activity GO:0032318 21 0.023
cell proliferation GO:0008283 116 0.023
Mouse
organophosphate catabolic process GO:0046434 81 0.023
protein catabolic process GO:0030163 162 0.023
regulation of gtp catabolic process GO:0033124 32 0.023
positive regulation of nucleotide catabolic process GO:0030813 28 0.023
regulation of neurogenesis GO:0050767 40 0.023
glycosyl compound catabolic process GO:1901658 79 0.023
multi multicellular organism process GO:0044706 390 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.023
Mouse Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.023
Fly
ribonucleotide catabolic process GO:0009261 75 0.023
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 2 0.022
cell migration GO:0016477 306 0.022
Mouse
macromolecular complex assembly GO:0065003 193 0.022
gtp catabolic process GO:0006184 46 0.022
cell motility GO:0048870 313 0.022
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 250 0.021
Mouse
localization of cell GO:0051674 313 0.021
Mouse
response to biotic stimulus GO:0009607 101 0.021
intracellular signal transduction GO:0035556 96 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.021
Mouse Fly
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.021
positive regulation of multicellular organism growth GO:0040018 352 0.021
positive regulation of developmental growth GO:0048639 354 0.021
regulation of developmental growth GO:0048638 389 0.021
axonal fasciculation GO:0007413 79 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.021
Mouse Fly
developmental growth GO:0048589 412 0.021
purine nucleotide catabolic process GO:0006195 75 0.020
purine nucleoside triphosphate metabolic process GO:0009144 87 0.020
nucleobase containing small molecule metabolic process GO:0055086 115 0.020
nucleoside triphosphate metabolic process GO:0009141 87 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.020
Mouse Fly
regulation of vulval development GO:0040028 248 0.020
nucleoside phosphate catabolic process GO:1901292 77 0.020
small gtpase mediated signal transduction GO:0007264 32 0.020
nucleobase containing compound catabolic process GO:0034655 114 0.020
regulation of anatomical structure morphogenesis GO:0022603 51 0.020
Mouse Fly
regulation of secretion GO:0051046 29 0.020
protein localization GO:0008104 205 0.020
hindgut development GO:0061525 3 0.020
regulation of cell proliferation GO:0042127 105 0.020
Mouse
response to temperature stimulus GO:0009266 66 0.020
nucleoside metabolic process GO:0009116 99 0.020
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.019
macromolecular complex subunit organization GO:0043933 320 0.019
cellular response to chemical stimulus GO:0070887 129 0.019
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.019
organic substance biosynthetic process GO:1901576 323 0.019
Mouse Fly
regulation of growth GO:0040008 409 0.019
negative regulation of signal transduction GO:0009968 60 0.019
cell type specific apoptotic process GO:0097285 4 0.019
cellular component assembly GO:0022607 293 0.018
cellular nitrogen compound catabolic process GO:0044270 119 0.018
positive regulation of rna biosynthetic process GO:1902680 102 0.018
Mouse Fly
regulation of nucleotide metabolic process GO:0006140 37 0.018
purine nucleotide metabolic process GO:0006163 95 0.018
nucleobase containing compound biosynthetic process GO:0034654 184 0.018
Mouse Fly
molting cycle GO:0042303 281 0.018
negative regulation of gene expression GO:0010629 217 0.018
Mouse Fly
purine containing compound metabolic process GO:0072521 95 0.018
regulation of locomotion GO:0040012 161 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 28 0.018
purine ribonucleoside metabolic process GO:0046128 92 0.018
regulation of behavior GO:0050795 97 0.018
pattern specification process GO:0007389 59 0.018
Mouse Fly
nucleoside triphosphate catabolic process GO:0009143 72 0.018
negative regulation of post embryonic development GO:0048581 208 0.017
positive regulation of phosphorus metabolic process GO:0010562 56 0.017
response to endoplasmic reticulum stress GO:0034976 71 0.017
ribonucleoside triphosphate catabolic process GO:0009203 72 0.017
axon guidance GO:0007411 82 0.017
neuron projection guidance GO:0097485 82 0.017
regulation of ras protein signal transduction GO:0046578 41 0.017
homeostatic process GO:0042592 51 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.017
Mouse
single organism catabolic process GO:0044712 129 0.017
purine containing compound catabolic process GO:0072523 75 0.017
carbohydrate derivative metabolic process GO:1901135 141 0.017
protein oligomerization GO:0051259 4 0.016
regulation of hormone secretion GO:0046883 2 0.016
female gamete generation GO:0007292 254 0.016
purine nucleoside metabolic process GO:0042278 92 0.016
cuticle development GO:0042335 100 0.016
Fly
nucleoside phosphate metabolic process GO:0006753 108 0.016
positive regulation of cellular biosynthetic process GO:0031328 109 0.016
Mouse Fly
cellular macromolecular complex assembly GO:0034622 184 0.016
negative regulation of cellular metabolic process GO:0031324 95 0.016
Mouse Fly
organonitrogen compound catabolic process GO:1901565 90 0.016
negative regulation of signaling GO:0023057 61 0.016
response to external biotic stimulus GO:0043207 101 0.015
positive regulation of response to stimulus GO:0048584 55 0.015
regulation of gtpase activity GO:0043087 30 0.015
oogenesis GO:0048477 229 0.015
epithelial cell proliferation GO:0050673 1 0.015
Mouse
regulation of post embryonic development GO:0048580 260 0.015
nucleoside catabolic process GO:0009164 78 0.015
hormone transport GO:0009914 2 0.015
ion transmembrane transport GO:0034220 91 0.015
ribose phosphate metabolic process GO:0019693 99 0.015
nitrogen compound transport GO:0071705 49 0.014
gastrulation GO:0007369 58 0.014
negative regulation of macromolecule metabolic process GO:0010605 229 0.014
Mouse Fly
intracellular receptor signaling pathway GO:0030522 2 0.014
regulation of transcription dna templated GO:0006355 164 0.014
Mouse Fly
organic substance transport GO:0071702 113 0.014
organophosphate metabolic process GO:0019637 125 0.014
gamete generation GO:0007276 461 0.014
Mouse
nucleotide metabolic process GO:0009117 108 0.014
sensory organ morphogenesis GO:0090596 2 0.014
organelle organization GO:0006996 783 0.014
Fly
muscle tissue development GO:0060537 1 0.014
phosphate containing compound metabolic process GO:0006796 232 0.014
chromosome organization GO:0051276 104 0.014
muscle structure development GO:0061061 191 0.013
regulation of mesoderm development GO:2000380 2 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.013
cell morphogenesis involved in differentiation GO:0000904 112 0.013
Mouse
negative regulation of developmental process GO:0051093 227 0.013
Mouse
peptide hormone secretion GO:0030072 2 0.013
nucleotide catabolic process GO:0009166 77 0.013
death GO:0016265 547 0.013
regulation of cellular catabolic process GO:0031329 51 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
heterocycle catabolic process GO:0046700 119 0.012
secretion by cell GO:0032940 138 0.012
positive regulation of neuron projection development GO:0010976 4 0.012
cellular response to abiotic stimulus GO:0071214 4 0.012
establishment of organelle localization GO:0051656 123 0.012
insulin secretion GO:0030073 2 0.012
ribonucleoside triphosphate metabolic process GO:0009199 87 0.012
eating behavior GO:0042755 59 0.012
embryonic morphogenesis GO:0048598 152 0.012
Mouse
dendrite development GO:0016358 42 0.012
response to acid chemical GO:0001101 4 0.012
negative regulation of multicellular organismal process GO:0051241 236 0.012
Mouse
regulation of catalytic activity GO:0050790 78 0.012
negative regulation of locomotion GO:0040013 21 0.011
membrane organization GO:0061024 135 0.011
positive regulation of molecular function GO:0044093 61 0.011
epithelial cell morphogenesis GO:0003382 2 0.011
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.011
mating behavior GO:0007617 32 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
hormone metabolic process GO:0042445 3 0.011
Fly
innate immune response GO:0045087 190 0.011
rna biosynthetic process GO:0032774 169 0.011
Mouse Fly
male mating behavior GO:0060179 26 0.011
negative regulation of vulval development GO:0040027 206 0.011
embryonic pattern specification GO:0009880 21 0.011
cell part morphogenesis GO:0032990 152 0.010
regulation of protein import into nucleus GO:0042306 3 0.010
cell recognition GO:0008037 85 0.010
positive regulation of hydrolase activity GO:0051345 38 0.010
cellular catabolic process GO:0044248 199 0.010
neurotransmitter transport GO:0006836 32 0.010
positive regulation of cellular protein catabolic process GO:1903364 3 0.010
pharyngeal pumping GO:0043050 58 0.010
germ cell development GO:0007281 351 0.010
response to wounding GO:0009611 4 0.010
regulation of pharyngeal pumping GO:0043051 36 0.010

lin-48 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.049
cardiovascular system disease DOID:1287 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
nervous system disease DOID:863 0 0.011