Caenorhabditis elegans

32 known processes

mlk-1 (CELE_K11D12.10)

Protein MLK-1

mlk-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of multicellular organismal process GO:0051239 726 0.397
Mouse Fly
regulation of multicellular organismal development GO:2000026 317 0.360
Mouse Fly
multicellular organism reproduction GO:0032504 819 0.322
Mouse Rat
regulation of gene expression GO:0010468 366 0.316
regulation of metabolic process GO:0019222 478 0.310
Human
signaling GO:0023052 401 0.277
Fly
positive regulation of rna biosynthetic process GO:1902680 102 0.267
regulation of macromolecule metabolic process GO:0060255 421 0.255
Human
multi organism reproductive process GO:0044703 867 0.238
Mouse Rat
regulation of developmental process GO:0050793 684 0.233
Mouse Fly
embryo development GO:0009790 3052 0.223
Fly
regulation of cellular metabolic process GO:0031323 305 0.223
Human
growth GO:0040007 562 0.223
Mouse Fly
multicellular organismal reproductive behavior GO:0033057 384 0.219
embryo development ending in birth or egg hatching GO:0009792 2992 0.217
Fly
locomotion GO:0040011 1634 0.209
gamete generation GO:0007276 461 0.203
Mouse Rat
sexual reproduction GO:0019953 546 0.187
Mouse Rat
post embryonic development GO:0009791 2152 0.182
Fly
multicellular organismal reproductive process GO:0048609 815 0.172
Mouse Rat
stress activated protein kinase signaling cascade GO:0031098 10 0.171
defense response GO:0006952 296 0.170
behavior GO:0007610 527 0.165
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.165
negative regulation of biological process GO:0048519 567 0.163
Human Fly
signal transduction GO:0007165 317 0.162
Fly
nucleobase containing compound biosynthetic process GO:0034654 184 0.160
organic substance biosynthetic process GO:1901576 323 0.157
sex differentiation GO:0007548 909 0.154
developmental process involved in reproduction GO:0003006 1165 0.153
gene expression GO:0010467 412 0.151
developmental growth GO:0048589 412 0.148
Mouse Fly
synaptic transmission GO:0007268 106 0.147
cellular macromolecule biosynthetic process GO:0034645 247 0.139
hermaphrodite genitalia development GO:0040035 734 0.138
macromolecule localization GO:0033036 771 0.128
multi organism reproductive behavior GO:0044705 387 0.128
regulation of nitrogen compound metabolic process GO:0051171 222 0.121
regulation of biological quality GO:0065008 741 0.119
Mouse
jnk cascade GO:0007254 8 0.119
cell death GO:0008219 547 0.116
positive regulation of nucleic acid templated transcription GO:1903508 102 0.115
cell cycle GO:0007049 526 0.114
oviposition GO:0018991 364 0.112
multicellular organismal aging GO:0010259 812 0.112
single organism reproductive process GO:0044702 1196 0.111
Mouse Rat
macromolecule modification GO:0043412 218 0.110
single organism signaling GO:0044700 401 0.109
Fly
cell development GO:0048468 696 0.108
Mouse Fly
transport GO:0006810 1093 0.108
multi multicellular organism process GO:0044706 390 0.107
response to chemical GO:0042221 356 0.105
establishment of localization GO:0051234 1171 0.100
regulation of signaling GO:0023051 172 0.096
Fly
nucleic acid metabolic process GO:0090304 299 0.096
organ development GO:0048513 1102 0.096
Fly
body morphogenesis GO:0010171 620 0.096
macromolecule biosynthetic process GO:0009059 250 0.091
lipid localization GO:0010876 573 0.088
reproductive behavior GO:0019098 387 0.088
receptor mediated endocytosis GO:0006898 715 0.084
organic cyclic compound biosynthetic process GO:1901362 195 0.084
gonad development GO:0008406 840 0.083
vesicle mediated transport GO:0016192 852 0.083
nucleobase containing compound metabolic process GO:0006139 406 0.083
regulation of primary metabolic process GO:0080090 292 0.082
Human
localization of cell GO:0051674 313 0.081
cellular biosynthetic process GO:0044249 315 0.080
reproductive structure development GO:0048608 850 0.078
positive regulation of cellular metabolic process GO:0031325 178 0.077
regulation of response to stimulus GO:0048583 243 0.077
Fly
positive regulation of cellular process GO:0048522 332 0.075
Human Mouse
heterocycle biosynthetic process GO:0018130 187 0.074
genitalia development GO:0048806 741 0.074
multicellular organism growth GO:0035264 385 0.073
regulation of growth GO:0040008 409 0.072
Mouse
innate immune response GO:0045087 190 0.071
apoptotic process GO:0006915 478 0.071
stress activated mapk cascade GO:0051403 10 0.071
maintenance of location GO:0051235 580 0.070
regulation of behavior GO:0050795 97 0.069
phosphorus metabolic process GO:0006793 232 0.068
programmed cell death GO:0012501 500 0.068
regulation of developmental growth GO:0048638 389 0.068
Mouse
regulation of transcription dna templated GO:0006355 164 0.068
protein modification process GO:0036211 207 0.067
regulation of multicellular organism growth GO:0040014 373 0.067
system process GO:0003008 136 0.066
cellular protein modification process GO:0006464 207 0.065
positive regulation of cell projection organization GO:0031346 4 0.065
Mouse
multi organism behavior GO:0051705 389 0.065
protein localization GO:0008104 205 0.065
reproductive system development GO:0061458 850 0.064
response to transition metal nanoparticle GO:1990267 18 0.064
regulation of nucleic acid templated transcription GO:1903506 165 0.063
negative regulation of metabolic process GO:0009892 240 0.062
Human
lipid storage GO:0019915 565 0.060
immune response GO:0006955 192 0.060
cellular response to organic substance GO:0071310 119 0.059
muscle tissue development GO:0060537 1 0.059
anatomical structure formation involved in morphogenesis GO:0048646 250 0.057
macromolecule catabolic process GO:0009057 202 0.056
aromatic compound biosynthetic process GO:0019438 192 0.056
regulation of cell communication GO:0010646 176 0.056
Fly
neurogenesis GO:0022008 236 0.055
Mouse Fly
positive regulation of multicellular organismal process GO:0051240 417 0.055
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.054
copulation GO:0007620 2 0.054
secretion by cell GO:0032940 138 0.054
positive regulation of developmental process GO:0051094 408 0.053
Mouse
development of primary sexual characteristics GO:0045137 840 0.053
ras protein signal transduction GO:0007265 31 0.053
regulation of multi organism process GO:0043900 69 0.052
cell cell signaling GO:0007267 118 0.052
response to wounding GO:0009611 4 0.051
response to external stimulus GO:0009605 289 0.051
Zebrafish
cellular component movement GO:0006928 388 0.050
positive regulation of gene expression GO:0010628 112 0.050
regulation of cell cycle GO:0051726 194 0.049
regulation of oviposition GO:0046662 43 0.049
cell division GO:0051301 262 0.048
protein metabolic process GO:0019538 422 0.048
oogenesis GO:0048477 229 0.048
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.048
phosphate containing compound metabolic process GO:0006796 232 0.048
positive regulation of phosphorus metabolic process GO:0010562 56 0.047
response to organic substance GO:0010033 131 0.047
negative regulation of macromolecule metabolic process GO:0010605 229 0.047
Human
nucleic acid templated transcription GO:0097659 169 0.047
intracellular signal transduction GO:0035556 96 0.046
aging GO:0007568 812 0.046
neuron differentiation GO:0030182 217 0.046
Mouse Fly
regulation of reproductive process GO:2000241 66 0.046
determination of adult lifespan GO:0008340 812 0.045
macromolecular complex subunit organization GO:0043933 320 0.045
Human Mouse Fly
positive regulation of protein kinase activity GO:0045860 18 0.045
regulation of catalytic activity GO:0050790 78 0.045
Human
organelle fission GO:0048285 363 0.044
negative regulation of cellular process GO:0048523 239 0.044
Human Fly
insemination GO:0007320 2 0.043
organelle organization GO:0006996 783 0.042
Human Mouse Rat Fly
positive regulation of multicellular organism growth GO:0040018 352 0.042
enzyme linked receptor protein signaling pathway GO:0007167 50 0.041
Fly
regeneration GO:0031099 4 0.041
regulation of neurotransmitter secretion GO:0046928 16 0.040
regulation of nervous system development GO:0051960 41 0.040
Mouse Fly
germ cell development GO:0007281 351 0.039
protein complex subunit organization GO:0071822 280 0.039
Human Mouse Fly
negative regulation of cell communication GO:0010648 61 0.039
Fly
regulation of cell development GO:0060284 49 0.038
Mouse Fly
cellular lipid metabolic process GO:0044255 40 0.038
response to abiotic stimulus GO:0009628 152 0.038
death GO:0016265 547 0.038
protein phosphorylation GO:0006468 85 0.037
cellular component morphogenesis GO:0032989 318 0.037
Mouse Fly
regulation of cell cycle process GO:0010564 145 0.037
positive regulation of developmental growth GO:0048639 354 0.037
Mouse
rna metabolic process GO:0016070 228 0.036
organic substance catabolic process GO:1901575 294 0.036
rna biosynthetic process GO:0032774 169 0.036
regulation of cell division GO:0051302 142 0.036
response to oxygen containing compound GO:1901700 44 0.036
meiotic nuclear division GO:0007126 300 0.036
cellular localization GO:0051641 360 0.036
cell migration GO:0016477 306 0.035
single organism transport GO:0044765 447 0.035
organelle localization GO:0051640 127 0.035
cellular response to abiotic stimulus GO:0071214 4 0.035
positive regulation of catalytic activity GO:0043085 59 0.034
regulation of biosynthetic process GO:0009889 189 0.034
rho protein signal transduction GO:0007266 2 0.034
establishment of localization in cell GO:0051649 318 0.034
regulation of rna metabolic process GO:0051252 173 0.033
negative regulation of gene expression GO:0010629 217 0.033
phosphorylation GO:0016310 116 0.033
positive regulation of cellular biosynthetic process GO:0031328 109 0.033
ribonucleoprotein complex assembly GO:0022618 4 0.033
establishment of organelle localization GO:0051656 123 0.033
regulation of signal transduction GO:0009966 135 0.032
Fly
neurotransmitter secretion GO:0007269 26 0.032
regulation of mapk cascade GO:0043408 23 0.032
positive regulation of growth GO:0045927 369 0.031
Mouse
regulation of macromolecule biosynthetic process GO:0010556 189 0.031
regulation of intracellular signal transduction GO:1902531 77 0.031
generation of neurons GO:0048699 235 0.031
Mouse Fly
endocytosis GO:0006897 819 0.030
regulation of rna biosynthetic process GO:2001141 165 0.030
cellular nitrogen compound biosynthetic process GO:0044271 192 0.030
catabolic process GO:0009056 318 0.029
small gtpase mediated signal transduction GO:0007264 32 0.029
single organism behavior GO:0044708 83 0.029
female gamete generation GO:0007292 254 0.029
activation of protein kinase activity GO:0032147 11 0.029
cell cycle process GO:0022402 482 0.029
regulation of neurotransmitter levels GO:0001505 36 0.029
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.028
cellular protein metabolic process GO:0044267 279 0.028
regulation of phosphate metabolic process GO:0019220 81 0.028
meiotic cell cycle GO:0051321 335 0.027
cell motility GO:0048870 313 0.027
carbohydrate biosynthetic process GO:0016051 4 0.027
embryonic body morphogenesis GO:0010172 49 0.027
asymmetric cell division GO:0008356 36 0.027
positive regulation of macromolecule metabolic process GO:0010604 149 0.026
regulation of cellular component organization GO:0051128 248 0.026
Human Mouse Fly
negative regulation of signal transduction GO:0009968 60 0.025
Fly
positive regulation of transcription dna templated GO:0045893 102 0.025
negative regulation of developmental process GO:0051093 227 0.025
Fly
neuromuscular junction development GO:0007528 2 0.025
Fly
regulation of phosphorylation GO:0042325 45 0.025
regulation of phosphorus metabolic process GO:0051174 81 0.025
regulation of localization GO:0032879 194 0.025
negative regulation of signaling GO:0023057 61 0.025
Fly
cell proliferation GO:0008283 116 0.024
protein catabolic process GO:0030163 162 0.024
cellular response to stress GO:0033554 162 0.024
positive regulation of neurotransmitter transport GO:0051590 11 0.024
regulation of nuclear division GO:0051783 115 0.024
mating GO:0007618 34 0.024
neuron development GO:0048666 199 0.024
Mouse Fly
mating behavior GO:0007617 32 0.024
regulation of nucleoside metabolic process GO:0009118 37 0.023
mapk cascade GO:0000165 31 0.023
regulation of cellular biosynthetic process GO:0031326 189 0.023
regulation of small gtpase mediated signal transduction GO:0051056 41 0.023
cellular component biogenesis GO:0044085 297 0.023
Human Mouse Rat Fly
single organism localization GO:1902578 518 0.023
secretion GO:0046903 147 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.023
macromolecular complex assembly GO:0065003 193 0.023
cellular protein complex assembly GO:0043623 178 0.023
regulation of meiotic cell cycle GO:0051445 136 0.023
positive regulation of metabolic process GO:0009893 187 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.022
transcription dna templated GO:0006351 168 0.022
positive regulation of phosphate metabolic process GO:0045937 56 0.022
biosynthetic process GO:0009058 323 0.022
establishment of mitotic spindle localization GO:0040001 41 0.022
regulation of cell proliferation GO:0042127 105 0.022
response to bacterium GO:0009617 86 0.022
muscle cell differentiation GO:0042692 171 0.022
regulation of organelle organization GO:0033043 164 0.022
Human Mouse
skeletal muscle organ development GO:0060538 3 0.021
single organism organelle organization GO:1902589 501 0.021
Human Mouse Rat Fly
small molecule metabolic process GO:0044281 186 0.021
regulation of molecular function GO:0065009 89 0.021
Human
cellular response to inorganic substance GO:0071241 3 0.021
establishment of spindle localization GO:0051293 51 0.020
post embryonic organ development GO:0048569 336 0.020
Fly
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.020
negative regulation of response to stimulus GO:0048585 73 0.020
Fly
positive regulation of intracellular transport GO:0032388 2 0.020
regulation of protein serine threonine kinase activity GO:0071900 18 0.020
aromatic compound catabolic process GO:0019439 116 0.020
regulation of map kinase activity GO:0043405 13 0.019
negative regulation of cellular metabolic process GO:0031324 95 0.019
Human
cytoskeleton organization GO:0007010 339 0.019
Human Mouse Rat Fly
positive regulation of transferase activity GO:0051347 21 0.019
organic substance transport GO:0071702 113 0.019
positive regulation of neurogenesis GO:0050769 4 0.019
Mouse
embryonic morphogenesis GO:0048598 152 0.019
inductive cell migration GO:0040039 145 0.019
head development GO:0060322 1 0.019
establishment or maintenance of cell polarity GO:0007163 63 0.019
cellular component assembly GO:0022607 293 0.019
Human Mouse Rat Fly
positive regulation of biosynthetic process GO:0009891 109 0.019
cell surface receptor signaling pathway GO:0007166 149 0.018
Fly
feminization of hermaphroditic germ line GO:0040022 34 0.018
carbohydrate derivative metabolic process GO:1901135 141 0.018
positive regulation of gtp catabolic process GO:0033126 28 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.018
chromosome organization GO:0051276 104 0.018
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.018
neurotransmitter transport GO:0006836 32 0.018
regulation of anatomical structure morphogenesis GO:0022603 51 0.018
Mouse Fly
cellular response to chemical stimulus GO:0070887 129 0.018
nitrogen compound transport GO:0071705 49 0.017
gtp catabolic process GO:0006184 46 0.017
single organism carbohydrate metabolic process GO:0044723 29 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.017
Fly
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 16 0.017
positive regulation of kinase activity GO:0033674 19 0.017
cellular response to growth factor stimulus GO:0071363 18 0.017
vulval development GO:0040025 333 0.017
protein complex biogenesis GO:0070271 186 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
regulation of neurogenesis GO:0050767 40 0.016
Mouse Fly
regulation of synaptic transmission GO:0050804 34 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.016
stem cell proliferation GO:0072089 9 0.016
cellular response to endogenous stimulus GO:0071495 32 0.016
posttranscriptional gene silencing by rna GO:0035194 143 0.016
muscle contraction GO:0006936 43 0.016
regulation of locomotion GO:0040012 161 0.016
regulation of kinase activity GO:0043549 29 0.016
oxoacid metabolic process GO:0043436 47 0.016
transcription from rna polymerase ii promoter GO:0006366 149 0.016
tissue development GO:0009888 112 0.016
Fly
nucleotide metabolic process GO:0009117 108 0.016
acetate ester transport GO:1901374 16 0.016
regulation of nucleotide metabolic process GO:0006140 37 0.015
positive regulation of cell cycle GO:0045787 55 0.015
regulation of transferase activity GO:0051338 31 0.015
Human
positive regulation of neuron differentiation GO:0045666 4 0.015
Mouse
muscle structure development GO:0061061 191 0.015
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.015
protein complex assembly GO:0006461 186 0.015
regulation of cellular protein metabolic process GO:0032268 75 0.015
Human
striated muscle cell development GO:0055002 157 0.015
signal transduction by phosphorylation GO:0023014 31 0.014
organic acid metabolic process GO:0006082 47 0.014
regulation of cell differentiation GO:0045595 81 0.014
Mouse Fly
oxidation reduction process GO:0055114 59 0.014
membrane organization GO:0061024 135 0.014
response to inorganic substance GO:0010035 50 0.014
cell morphogenesis GO:0000902 163 0.014
Mouse Fly
oocyte construction GO:0007308 2 0.014
negative regulation of neurogenesis GO:0050768 4 0.014
Fly
regulation of protein kinase activity GO:0045859 28 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
positive regulation of rna metabolic process GO:0051254 103 0.014
regulation of cell projection organization GO:0031344 38 0.014
Mouse Fly
cell projection organization GO:0030030 231 0.014
Mouse Fly
neuron projection development GO:0031175 187 0.013
Mouse Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
response to growth factor GO:0070848 18 0.013
mitotic cell cycle process GO:1903047 194 0.013
actin cytoskeleton organization GO:0030036 184 0.013
Human Mouse Rat Fly
response to other organism GO:0051707 101 0.013
Zebrafish
single organism biosynthetic process GO:0044711 91 0.013
chromosome segregation GO:0007059 180 0.013
oocyte development GO:0048599 44 0.013
male gamete generation GO:0048232 41 0.013
Mouse Rat
regulation of cytoplasmic transport GO:1903649 3 0.013
cellular catabolic process GO:0044248 199 0.013
regulation of epithelial cell differentiation GO:0030856 4 0.013
single organism cellular localization GO:1902580 72 0.012
posttranscriptional regulation of gene expression GO:0010608 166 0.012
cell type specific apoptotic process GO:0097285 4 0.012
oocyte differentiation GO:0009994 45 0.012
locomotory behavior GO:0007626 40 0.012
positive regulation of molecular function GO:0044093 61 0.012
regulation of neurotransmitter transport GO:0051588 16 0.012
negative regulation of post embryonic development GO:0048581 208 0.012
meiotic chromosome segregation GO:0045132 139 0.012
positive regulation of nucleotide metabolic process GO:0045981 28 0.012
purine nucleotide catabolic process GO:0006195 75 0.012
rna interference GO:0016246 137 0.012
regulation of gene expression epigenetic GO:0040029 163 0.012
negative regulation of bmp signaling pathway GO:0030514 1 0.012
regulation of meiosis GO:0040020 94 0.012
nucleoside triphosphate metabolic process GO:0009141 87 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 12 0.012
regulation of nucleotide catabolic process GO:0030811 35 0.012
single fertilization GO:0007338 61 0.011
feeding behavior GO:0007631 70 0.011
regulation of cellular component movement GO:0051270 62 0.011
response to heat GO:0009408 50 0.011
hermaphrodite germ line sex determination GO:0040021 48 0.011
neurological system process GO:0050877 53 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.011
somatic sex determination GO:0018993 5 0.011
cellular macromolecular complex assembly GO:0034622 184 0.011
positive regulation of mapk cascade GO:0043410 14 0.011
regulation of programmed cell death GO:0043067 50 0.011
epithelial cell proliferation GO:0050673 1 0.011
spicule insertion GO:0034609 2 0.011
membrane depolarization GO:0051899 1 0.011
response to peptide hormone GO:0043434 14 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.010
carbohydrate derivative catabolic process GO:1901136 82 0.010
molting cycle GO:0042303 281 0.010
purine ribonucleoside catabolic process GO:0046130 75 0.010
regulation of protein modification process GO:0031399 46 0.010
Human
fertilization GO:0009566 63 0.010
muscle system process GO:0003012 43 0.010
gene silencing by rna GO:0031047 143 0.010

mlk-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org