Caenorhabditis elegans

14 known processes

his-63 (CELE_F22B3.2)

Protein HIS-63

his-63 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gonad development GO:0008406 840 0.607
Worm
genitalia development GO:0048806 741 0.598
Worm
reproductive system development GO:0061458 850 0.592
Worm
reproductive structure development GO:0048608 850 0.536
Worm
development of primary sexual characteristics GO:0045137 840 0.525
Worm
digestive system development GO:0055123 122 0.524
Worm
hermaphrodite genitalia development GO:0040035 734 0.517
Worm
single organism reproductive process GO:0044702 1196 0.480
Worm
digestive tract development GO:0048565 122 0.476
Worm
locomotion GO:0040011 1634 0.471
Worm
developmental process involved in reproduction GO:0003006 1165 0.441
Worm
sex differentiation GO:0007548 909 0.437
Worm
post embryonic development GO:0009791 2152 0.427
embryo development GO:0009790 3052 0.405
embryo development ending in birth or egg hatching GO:0009792 2992 0.405
organ development GO:0048513 1102 0.393
Worm
pharynx development GO:0060465 51 0.379
Worm
tube development GO:0035295 126 0.378
Worm
defense response GO:0006952 296 0.323
multicellular organismal reproductive behavior GO:0033057 384 0.263
oviposition GO:0018991 364 0.255
multicellular organism reproduction GO:0032504 819 0.251
multicellular organismal reproductive process GO:0048609 815 0.224
cellular nitrogen compound biosynthetic process GO:0044271 192 0.211
transcription dna templated GO:0006351 168 0.207
cellular macromolecule biosynthetic process GO:0034645 247 0.202
meiotic cell cycle process GO:1903046 170 0.191
heterocycle biosynthetic process GO:0018130 187 0.187
chromosome organization GO:0051276 104 0.172
meiotic cell cycle GO:0051321 335 0.169
regulation of transcription dna templated GO:0006355 164 0.160
cellular biosynthetic process GO:0044249 315 0.156
organelle organization GO:0006996 783 0.154
rna biosynthetic process GO:0032774 169 0.149
nucleobase containing compound metabolic process GO:0006139 406 0.142
nucleic acid metabolic process GO:0090304 299 0.142
regulation of rna biosynthetic process GO:2001141 165 0.141
body morphogenesis GO:0010171 620 0.141
Worm
aromatic compound biosynthetic process GO:0019438 192 0.138
regulation of nitrogen compound metabolic process GO:0051171 222 0.136
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.131
cellular response to dna damage stimulus GO:0006974 41 0.128
organic cyclic compound biosynthetic process GO:1901362 195 0.127
behavior GO:0007610 527 0.125
multi organism behavior GO:0051705 389 0.124
multi organism reproductive process GO:0044703 867 0.124
multi organism reproductive behavior GO:0044705 387 0.124
negative regulation of gene expression epigenetic GO:0045814 2 0.123
negative regulation of macromolecule metabolic process GO:0010605 229 0.122
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.122
rna metabolic process GO:0016070 228 0.120
regulation of nucleic acid templated transcription GO:1903506 165 0.120
regulation of macromolecule metabolic process GO:0060255 421 0.108
nucleobase containing compound biosynthetic process GO:0034654 184 0.108
dna repair GO:0006281 23 0.105
vesicle mediated transport GO:0016192 852 0.104
multicellular organismal aging GO:0010259 812 0.103
Worm
multi multicellular organism process GO:0044706 390 0.103
transcription from rna polymerase ii promoter GO:0006366 149 0.102
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.101
negative regulation of nucleic acid templated transcription GO:1903507 53 0.099
macromolecular complex subunit organization GO:0043933 320 0.098
organic substance biosynthetic process GO:1901576 323 0.089
negative regulation of gene expression GO:0010629 217 0.088
chromatin assembly or disassembly GO:0006333 1 0.088
negative regulation of transcription dna templated GO:0045892 53 0.087
macromolecule localization GO:0033036 771 0.087
reproductive behavior GO:0019098 387 0.086
regulation of cellular biosynthetic process GO:0031326 189 0.084
regulation of biosynthetic process GO:0009889 189 0.084
regulation of gene expression GO:0010468 366 0.083
nucleic acid templated transcription GO:0097659 169 0.082
establishment of localization GO:0051234 1171 0.081
immune response GO:0006955 192 0.081
biosynthetic process GO:0009058 323 0.081
sexual reproduction GO:0019953 546 0.080
regulation of metabolic process GO:0019222 478 0.078
cell cycle process GO:0022402 482 0.077
regulation of rna metabolic process GO:0051252 173 0.077
dna metabolic process GO:0006259 74 0.077
negative regulation of rna biosynthetic process GO:1902679 53 0.075
determination of adult lifespan GO:0008340 812 0.074
Worm
cell cycle GO:0007049 526 0.073
negative regulation of biological process GO:0048519 567 0.072
macromolecule biosynthetic process GO:0009059 250 0.071
regulation of primary metabolic process GO:0080090 292 0.070
aging GO:0007568 812 0.070
Worm
cell death GO:0008219 547 0.070
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.069
maintenance of location GO:0051235 580 0.069
negative regulation of biosynthetic process GO:0009890 65 0.067
lipid storage GO:0019915 565 0.066
receptor mediated endocytosis GO:0006898 715 0.066
lipid localization GO:0010876 573 0.066
programmed cell death GO:0012501 500 0.065
transport GO:0006810 1093 0.063
gene expression GO:0010467 412 0.061
regulation of biological quality GO:0065008 741 0.060
negative regulation of metabolic process GO:0009892 240 0.059
endocytosis GO:0006897 819 0.057
chromatin organization GO:0006325 32 0.055
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.055
vulval development GO:0040025 333 0.054
negative regulation of cellular process GO:0048523 239 0.054
cell development GO:0048468 696 0.053
anatomical structure formation involved in morphogenesis GO:0048646 250 0.053
regulation of cellular metabolic process GO:0031323 305 0.052
negative regulation of cellular biosynthetic process GO:0031327 65 0.052
single organism transport GO:0044765 447 0.051
positive regulation of cellular metabolic process GO:0031325 178 0.050
single organism localization GO:1902578 518 0.049
single organism organelle organization GO:1902589 501 0.048
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.046
apoptotic process GO:0006915 478 0.046
cellular component morphogenesis GO:0032989 318 0.046
regulation of macromolecule biosynthetic process GO:0010556 189 0.046
post embryonic organ development GO:0048569 336 0.046
death GO:0016265 547 0.046
cellular response to stress GO:0033554 162 0.046
innate immune response GO:0045087 190 0.045
positive regulation of cellular biosynthetic process GO:0031328 109 0.044
cellular component biogenesis GO:0044085 297 0.044
establishment of localization in cell GO:0051649 318 0.044
regulation of gene expression epigenetic GO:0040029 163 0.043
positive regulation of metabolic process GO:0009893 187 0.042
head development GO:0060322 1 0.042
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.042
protein complex subunit organization GO:0071822 280 0.041
positive regulation of cellular process GO:0048522 332 0.040
cellular localization GO:0051641 360 0.039
cellular component assembly GO:0022607 293 0.039
positive regulation of biosynthetic process GO:0009891 109 0.037
protein metabolic process GO:0019538 422 0.036
organelle fission GO:0048285 363 0.036
gene silencing GO:0016458 143 0.036
macromolecule modification GO:0043412 218 0.036
cytoskeleton organization GO:0007010 339 0.036
organelle assembly GO:0070925 214 0.036
regulation of nematode larval development GO:0061062 260 0.035
nucleus organization GO:0006997 38 0.035
protein complex biogenesis GO:0070271 186 0.035
cellular macromolecular complex assembly GO:0034622 184 0.035
meiotic nuclear division GO:0007126 300 0.035
regulation of multicellular organismal process GO:0051239 726 0.035
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.035
actin filament based process GO:0030029 191 0.034
cellular protein metabolic process GO:0044267 279 0.034
negative regulation of nematode larval development GO:0061064 208 0.034
regulation of developmental process GO:0050793 684 0.034
muscle cell development GO:0055001 158 0.034
cellular component assembly involved in morphogenesis GO:0010927 183 0.033
macromolecular complex assembly GO:0065003 193 0.033
secretion by cell GO:0032940 138 0.033
actin cytoskeleton organization GO:0030036 184 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.032
negative regulation of rna metabolic process GO:0051253 53 0.032
developmental growth GO:0048589 412 0.032
cellular protein complex assembly GO:0043623 178 0.032
regulation of developmental growth GO:0048638 389 0.031
gamete generation GO:0007276 461 0.031
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.031
protein complex assembly GO:0006461 186 0.031
regulation of vulval development GO:0040028 248 0.031
positive regulation of rna metabolic process GO:0051254 103 0.030
negative regulation of vulval development GO:0040027 206 0.030
negative regulation of cellular metabolic process GO:0031324 95 0.029
regulation of multicellular organism growth GO:0040014 373 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.029
catabolic process GO:0009056 318 0.029
regulation of growth GO:0040008 409 0.029
actomyosin structure organization GO:0031032 154 0.029
myofibril assembly GO:0030239 154 0.028
cellular protein modification process GO:0006464 207 0.028
multicellular organism growth GO:0035264 385 0.028
regulation of cellular component organization GO:0051128 248 0.028
cell division GO:0051301 262 0.028
growth GO:0040007 562 0.027
protein modification process GO:0036211 207 0.027
molting cycle GO:0042303 281 0.027
positive regulation of multicellular organism growth GO:0040018 352 0.026
striated muscle cell differentiation GO:0051146 158 0.026
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.026
positive regulation of developmental process GO:0051094 408 0.026
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.026
striated muscle cell development GO:0055002 157 0.026
regulation of organelle organization GO:0033043 164 0.026
germ cell development GO:0007281 351 0.025
myosin filament organization GO:0031033 138 0.025
positive regulation of transcription dna templated GO:0045893 102 0.025
positive regulation of growth GO:0045927 369 0.025
positive regulation of developmental growth GO:0048639 354 0.024
positive regulation of rna biosynthetic process GO:1902680 102 0.024
striated muscle myosin thick filament assembly GO:0071688 138 0.024
secretion GO:0046903 147 0.024
regulation of multicellular organismal development GO:2000026 317 0.024
positive regulation of macromolecule metabolic process GO:0010604 149 0.023
myosin filament assembly GO:0031034 138 0.023
negative regulation of post embryonic development GO:0048581 208 0.023
muscle cell differentiation GO:0042692 171 0.023
muscle structure development GO:0061061 191 0.023
regulation of post embryonic development GO:0048580 260 0.023
localization of cell GO:0051674 313 0.022
regulation of meiotic cell cycle GO:0051445 136 0.022
meiotic chromosome segregation GO:0045132 139 0.022
negative regulation of developmental process GO:0051093 227 0.021
positive regulation of multicellular organismal process GO:0051240 417 0.021
chromosome segregation GO:0007059 180 0.021
response to topologically incorrect protein GO:0035966 82 0.021
small molecule metabolic process GO:0044281 186 0.021
cell migration GO:0016477 306 0.021
cellular component movement GO:0006928 388 0.021
organonitrogen compound metabolic process GO:1901564 151 0.020
regulation of cell cycle GO:0051726 194 0.020
macromolecule catabolic process GO:0009057 202 0.019
posttranscriptional regulation of gene expression GO:0010608 166 0.019
cell motility GO:0048870 313 0.018
single organism signaling GO:0044700 401 0.018
positive regulation of gene expression GO:0010628 112 0.018
chromatin modification GO:0016568 32 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.018
positive regulation of nucleic acid templated transcription GO:1903508 102 0.018
organic substance catabolic process GO:1901575 294 0.017
sensory organ morphogenesis GO:0090596 2 0.017
cellular catabolic process GO:0044248 199 0.017
negative regulation of multicellular organismal process GO:0051241 236 0.017
positive regulation of nematode larval development GO:0061063 54 0.017
response to external stimulus GO:0009605 289 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
oogenesis GO:0048477 229 0.016
cell type specific apoptotic process GO:0097285 4 0.016
response to chemical GO:0042221 356 0.016
female gamete generation GO:0007292 254 0.016
mitotic cell cycle process GO:1903047 194 0.015
heterocycle catabolic process GO:0046700 119 0.015
cellular nitrogen compound catabolic process GO:0044270 119 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
inductive cell migration GO:0040039 145 0.015
regulation of cell cycle process GO:0010564 145 0.015
dauer larval development GO:0040024 92 0.015
signaling GO:0023052 401 0.015
response to wounding GO:0009611 4 0.014
regulation of mitotic cell cycle GO:0007346 76 0.014
cellular response to topologically incorrect protein GO:0035967 76 0.014
posttranscriptional gene silencing GO:0016441 143 0.014
regulation of localization GO:0032879 194 0.014
regulation of nuclear division GO:0051783 115 0.014
histone modification GO:0016570 30 0.014
covalent chromatin modification GO:0016569 30 0.014
regulation of meiosis GO:0040020 94 0.014
cell morphogenesis GO:0000902 163 0.014
posttranscriptional gene silencing by rna GO:0035194 143 0.014
signal transduction GO:0007165 317 0.013
neuromuscular junction development GO:0007528 2 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
protein localization GO:0008104 205 0.013
defense response to other organism GO:0098542 100 0.013
regulation of cell division GO:0051302 142 0.013
gene silencing by rna GO:0031047 143 0.013
rna interference GO:0016246 137 0.013
cell proliferation GO:0008283 116 0.013
fertilization GO:0009566 63 0.013
response to abiotic stimulus GO:0009628 152 0.013
protein oligomerization GO:0051259 4 0.013
positive regulation of neuron differentiation GO:0045666 4 0.013
regulation of cytoplasmic transport GO:1903649 3 0.013
organic cyclic compound catabolic process GO:1901361 119 0.012
ribose phosphate metabolic process GO:0019693 99 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
microtubule based process GO:0007017 182 0.012
nucleobase containing compound catabolic process GO:0034655 114 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
cell projection organization GO:0030030 231 0.012
apoptotic cell clearance GO:0043277 111 0.012
amine metabolic process GO:0009308 15 0.012
regulation of apoptotic signaling pathway GO:2001233 1 0.012
regulation of lipid metabolic process GO:0019216 4 0.012
positive regulation of vulval development GO:0040026 52 0.012
cellular ketone metabolic process GO:0042180 14 0.012
protein catabolic process GO:0030163 162 0.012
establishment of organelle localization GO:0051656 123 0.011
single organism catabolic process GO:0044712 129 0.011
cell substrate adhesion GO:0031589 1 0.011
organic acid metabolic process GO:0006082 47 0.011
response to unfolded protein GO:0006986 71 0.011
feeding behavior GO:0007631 70 0.011
carboxylic acid metabolic process GO:0019752 34 0.011
cell morphogenesis involved in differentiation GO:0000904 112 0.011
phagocytosis GO:0006909 115 0.011
positive regulation of post embryonic development GO:0048582 54 0.011
oxoacid metabolic process GO:0043436 47 0.011
aromatic compound catabolic process GO:0019439 116 0.011
cellular amine metabolic process GO:0044106 15 0.011
positive regulation of neurogenesis GO:0050769 4 0.011
generation of neurons GO:0048699 235 0.011
regulation of response to stimulus GO:0048583 243 0.011
phosphorus metabolic process GO:0006793 232 0.011
system process GO:0003008 136 0.011
neuron projection development GO:0031175 187 0.011
pronuclear migration GO:0035046 51 0.011
embryonic morphogenesis GO:0048598 152 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.010
cuticle development GO:0042335 100 0.010
response to biotic stimulus GO:0009607 101 0.010
regulation of cell proliferation GO:0042127 105 0.010
ribosome biogenesis GO:0042254 4 0.010
response to external biotic stimulus GO:0043207 101 0.010
epithelial tube morphogenesis GO:0060562 1 0.010
ribonucleotide metabolic process GO:0009259 99 0.010
regulation of nucleocytoplasmic transport GO:0046822 3 0.010

his-63 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
nervous system disease DOID:863 0 0.010