Caenorhabditis elegans

87 known processes

hpl-1 (CELE_K08H2.6)

Protein HPL-1

hpl-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.350
embryo development ending in birth or egg hatching GO:0009792 2992 0.286
cell death GO:0008219 547 0.228
body morphogenesis GO:0010171 620 0.189
locomotion GO:0040011 1634 0.163
post embryonic development GO:0009791 2152 0.151
organ development GO:0048513 1102 0.143
single organism signaling GO:0044700 401 0.140
developmental process involved in reproduction GO:0003006 1165 0.130
signal transduction GO:0007165 317 0.107
multicellular organismal reproductive process GO:0048609 815 0.105
regulation of developmental process GO:0050793 684 0.101
death GO:0016265 547 0.096
apoptotic process GO:0006915 478 0.093
signaling GO:0023052 401 0.089
programmed cell death GO:0012501 500 0.088
cell migration GO:0016477 306 0.088
cell surface receptor signaling pathway GO:0007166 149 0.083
regulation of biological quality GO:0065008 741 0.080
Fly
multicellular organismal aging GO:0010259 812 0.080
multicellular organismal reproductive behavior GO:0033057 384 0.079
multi organism reproductive process GO:0044703 867 0.078
cell morphogenesis GO:0000902 163 0.076
multicellular organism reproduction GO:0032504 819 0.073
sex differentiation GO:0007548 909 0.072
macromolecule localization GO:0033036 771 0.071
multi organism reproductive behavior GO:0044705 387 0.067
multi multicellular organism process GO:0044706 390 0.067
lipid storage GO:0019915 565 0.067
localization of cell GO:0051674 313 0.066
determination of adult lifespan GO:0008340 812 0.066
negative regulation of biological process GO:0048519 567 0.065
single organism reproductive process GO:0044702 1196 0.064
reproductive structure development GO:0048608 850 0.062
axonogenesis GO:0007409 102 0.061
cell motility GO:0048870 313 0.061
cellular protein metabolic process GO:0044267 279 0.061
Fly
oviposition GO:0018991 364 0.059
meiotic nuclear division GO:0007126 300 0.058
regulation of localization GO:0032879 194 0.057
lipid localization GO:0010876 573 0.057
maintenance of location GO:0051235 580 0.056
post embryonic organ development GO:0048569 336 0.056
cell development GO:0048468 696 0.052
positive regulation of cellular process GO:0048522 332 0.052
Fly
cell morphogenesis involved in differentiation GO:0000904 112 0.051
developmental growth GO:0048589 412 0.049
Worm
response to chemical GO:0042221 356 0.049
Worm
cell type specific apoptotic process GO:0097285 4 0.048
protein modification process GO:0036211 207 0.046
Fly
growth GO:0040007 562 0.046
wnt signaling pathway GO:0016055 27 0.046
nucleic acid metabolic process GO:0090304 299 0.045
Human Mouse Fly
negative regulation of macromolecule metabolic process GO:0010605 229 0.045
Human Mouse Fly
meiotic cell cycle GO:0051321 335 0.044
establishment of localization in cell GO:0051649 318 0.043
aging GO:0007568 812 0.043
organelle organization GO:0006996 783 0.042
Fly
regulation of primary metabolic process GO:0080090 292 0.041
Human Mouse Fly
oxoacid metabolic process GO:0043436 47 0.040
regulation of developmental growth GO:0048638 389 0.040
Worm
neuron projection guidance GO:0097485 82 0.039
establishment of localization GO:0051234 1171 0.039
hermaphrodite genitalia development GO:0040035 734 0.039
transport GO:0006810 1093 0.039
multi organism behavior GO:0051705 389 0.038
regulation of cell communication GO:0010646 176 0.038
negative regulation of cellular process GO:0048523 239 0.038
axon development GO:0061564 163 0.038
regulation of locomotion GO:0040012 161 0.037
vesicle mediated transport GO:0016192 852 0.037
reproductive behavior GO:0019098 387 0.036
organelle fission GO:0048285 363 0.036
neurogenesis GO:0022008 236 0.036
Fly
regulation of cellular component organization GO:0051128 248 0.036
Fly
cellular component morphogenesis GO:0032989 318 0.036
biosynthetic process GO:0009058 323 0.036
Human Mouse Fly
negative regulation of multicellular organismal process GO:0051241 236 0.035
cell part morphogenesis GO:0032990 152 0.035
germ cell development GO:0007281 351 0.034
vulval development GO:0040025 333 0.034
regulation of gene expression GO:0010468 366 0.034
Human Mouse Fly
regulation of multicellular organismal process GO:0051239 726 0.034
regulation of metabolic process GO:0019222 478 0.033
Human Mouse Fly
cellular ketone metabolic process GO:0042180 14 0.033
multicellular organism growth GO:0035264 385 0.033
Worm
positive regulation of multicellular organism growth GO:0040018 352 0.033
Worm
negative regulation of developmental process GO:0051093 227 0.032
molting cycle GO:0042303 281 0.032
nucleobase containing compound metabolic process GO:0006139 406 0.032
Human Mouse Fly
neuron projection development GO:0031175 187 0.032
regulation of multicellular organism growth GO:0040014 373 0.031
Worm
macromolecule modification GO:0043412 218 0.031
Fly
canonical wnt signaling pathway GO:0060070 3 0.031
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.030
regulation of cellular ketone metabolic process GO:0010565 3 0.030
negative regulation of metabolic process GO:0009892 240 0.029
Human Mouse Fly
regulation of cellular metabolic process GO:0031323 305 0.028
Human Mouse Fly
cell projection organization GO:0030030 231 0.028
development of primary sexual characteristics GO:0045137 840 0.028
behavior GO:0007610 527 0.027
Worm
anatomical structure formation involved in morphogenesis GO:0048646 250 0.027
negative regulation of neurogenesis GO:0050768 4 0.027
reproductive system development GO:0061458 850 0.027
cellular component biogenesis GO:0044085 297 0.027
Fly
regulation of growth GO:0040008 409 0.027
neuron differentiation GO:0030182 217 0.026
oogenesis GO:0048477 229 0.026
Worm
cell cycle process GO:0022402 482 0.026
chemotaxis GO:0006935 120 0.026
gonad development GO:0008406 840 0.026
cellular protein modification process GO:0006464 207 0.026
Fly
single organism organelle organization GO:1902589 501 0.026
Fly
taxis GO:0042330 128 0.025
cytoskeleton organization GO:0007010 339 0.025
enzyme linked receptor protein signaling pathway GO:0007167 50 0.025
muscle structure development GO:0061061 191 0.025
cell cycle GO:0007049 526 0.025
positive regulation of metabolic process GO:0009893 187 0.024
Fly
sexual reproduction GO:0019953 546 0.024
endocytosis GO:0006897 819 0.024
neuron projection morphogenesis GO:0048812 114 0.024
gamete generation GO:0007276 461 0.024
negative regulation of vulval development GO:0040027 206 0.024
intracellular signal transduction GO:0035556 96 0.023
regulation of response to stimulus GO:0048583 243 0.023
cellular macromolecular complex assembly GO:0034622 184 0.023
nervous system development GO:0007399 253 0.023
Fly
gene expression GO:0010467 412 0.023
Human Mouse Fly
regulation of cell motility GO:2000145 57 0.022
receptor mediated endocytosis GO:0006898 715 0.022
phosphate containing compound metabolic process GO:0006796 232 0.022
tube development GO:0035295 126 0.022
positive regulation of developmental growth GO:0048639 354 0.022
Worm
positive regulation of secretion GO:0051047 17 0.022
macromolecular complex subunit organization GO:0043933 320 0.021
Fly
generation of neurons GO:0048699 235 0.021
striated muscle cell differentiation GO:0051146 158 0.021
phosphorus metabolic process GO:0006793 232 0.021
regulation of cellular protein metabolic process GO:0032268 75 0.021
Fly
protein metabolic process GO:0019538 422 0.021
Fly
neuron development GO:0048666 199 0.021
posttranscriptional gene silencing by rna GO:0035194 143 0.020
regulation of cellular component movement GO:0051270 62 0.020
regionalization GO:0003002 31 0.020
positive regulation of biosynthetic process GO:0009891 109 0.020
regulation of macromolecule metabolic process GO:0060255 421 0.020
Human Mouse Fly
macromolecular complex assembly GO:0065003 193 0.020
Fly
muscle cell differentiation GO:0042692 171 0.020
macromolecule biosynthetic process GO:0009059 250 0.020
Human Mouse Fly
posttranscriptional regulation of gene expression GO:0010608 166 0.020
cellular macromolecule biosynthetic process GO:0034645 247 0.020
Human Mouse Fly
regulation of canonical wnt signaling pathway GO:0060828 1 0.019
regulation of multicellular organismal development GO:2000026 317 0.019
gene silencing by rna GO:0031047 143 0.019
cellular component movement GO:0006928 388 0.019
cellular response to stress GO:0033554 162 0.019
transcription from rna polymerase ii promoter GO:0006366 149 0.019
organic substance catabolic process GO:1901575 294 0.019
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.018
catabolic process GO:0009056 318 0.018
embryonic pattern specification GO:0009880 21 0.018
rna interference GO:0016246 137 0.018
positive regulation of developmental process GO:0051094 408 0.018
Worm
regulation of signal transduction GO:0009966 135 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
secretion GO:0046903 147 0.017
cellular amine metabolic process GO:0044106 15 0.017
membrane organization GO:0061024 135 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.017
membrane invagination GO:0010324 98 0.017
female gamete generation GO:0007292 254 0.017
Worm
amine metabolic process GO:0009308 15 0.017
organelle assembly GO:0070925 214 0.016
cellular component assembly GO:0022607 293 0.016
Fly
cell projection morphogenesis GO:0048858 148 0.016
chromosome segregation GO:0007059 180 0.016
actin filament based process GO:0030029 191 0.016
regulation of gene expression epigenetic GO:0040029 163 0.016
Fly
regulation of phosphorus metabolic process GO:0051174 81 0.016
peptidyl tyrosine phosphorylation GO:0018108 2 0.016
regulation of post embryonic development GO:0048580 260 0.016
cellular localization GO:0051641 360 0.016
protein complex assembly GO:0006461 186 0.016
regulation of transport GO:0051049 91 0.016
response to organic substance GO:0010033 131 0.015
gene silencing GO:0016458 143 0.015
Fly
dna metabolic process GO:0006259 74 0.015
Fly
pharynx development GO:0060465 51 0.015
cellular biosynthetic process GO:0044249 315 0.015
Human Mouse Fly
cellular response to organic substance GO:0071310 119 0.015
protein complex subunit organization GO:0071822 280 0.015
head development GO:0060322 1 0.015
regulation of cell cycle process GO:0010564 145 0.015
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.015
axon guidance GO:0007411 82 0.015
cell recognition GO:0008037 85 0.015
regulation of cell division GO:0051302 142 0.015
positive regulation of cellular metabolic process GO:0031325 178 0.014
Fly
organonitrogen compound metabolic process GO:1901564 151 0.014
positive regulation of multicellular organismal process GO:0051240 417 0.014
Worm
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.014
cellular catabolic process GO:0044248 199 0.014
organic substance biosynthetic process GO:1901576 323 0.014
Human Mouse Fly
rna metabolic process GO:0016070 228 0.014
Human Mouse Fly
regulation of cell cycle GO:0051726 194 0.014
response to external stimulus GO:0009605 289 0.014
cellular protein complex assembly GO:0043623 178 0.014
regulation of organ morphogenesis GO:2000027 4 0.014
posttranscriptional gene silencing GO:0016441 143 0.014
regulation of cell proliferation GO:0042127 105 0.014
regulation of apoptotic signaling pathway GO:2001233 1 0.014
response to abiotic stimulus GO:0009628 152 0.014
asymmetric protein localization GO:0008105 35 0.014
genitalia development GO:0048806 741 0.013
positive regulation of growth GO:0045927 369 0.013
single organism transport GO:0044765 447 0.013
transcription dna templated GO:0006351 168 0.013
Human Mouse Fly
actin cytoskeleton organization GO:0030036 184 0.013
negative regulation of post embryonic development GO:0048581 208 0.013
regulation of response to wounding GO:1903034 1 0.013
organic acid metabolic process GO:0006082 47 0.013
single organism localization GO:1902578 518 0.013
cellular response to chemical stimulus GO:0070887 129 0.013
protein complex biogenesis GO:0070271 186 0.013
regulation of organelle organization GO:0033043 164 0.012
Fly
positive regulation of nucleic acid templated transcription GO:1903508 102 0.012
regulation of molecular function GO:0065009 89 0.012
cell cell signaling GO:0007267 118 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.012
Human Mouse Fly
regeneration GO:0031099 4 0.012
aromatic compound biosynthetic process GO:0019438 192 0.012
Human Mouse Fly
cell division GO:0051301 262 0.012
organic cyclic compound biosynthetic process GO:1901362 195 0.012
Human Mouse Fly
negative regulation of cell communication GO:0010648 61 0.012
defense response GO:0006952 296 0.012
regulation of epithelial cell proliferation GO:0050678 1 0.012
epithelial cell proliferation GO:0050673 1 0.012
neuron projection extension GO:1990138 37 0.012
positive regulation of rna biosynthetic process GO:1902680 102 0.011
macromolecule catabolic process GO:0009057 202 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.011
Human Mouse Fly
positive regulation of cell communication GO:0010647 69 0.011
muscle organ morphogenesis GO:0048644 4 0.011
regulation of nuclear division GO:0051783 115 0.011
digestive system development GO:0055123 122 0.011
neuron apoptotic process GO:0051402 4 0.011
heterocycle biosynthetic process GO:0018130 187 0.011
Human Mouse Fly
regulation of wnt signaling pathway GO:0030111 9 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.011
Fly
rna localization GO:0006403 3 0.011
negative regulation of biosynthetic process GO:0009890 65 0.011
Human Mouse Fly
chemosensory behavior GO:0007635 33 0.011
Worm
regulation of vulval development GO:0040028 248 0.011
cell growth GO:0016049 44 0.011
organelle localization GO:0051640 127 0.010
negative regulation of gene expression GO:0010629 217 0.010
Human Mouse Fly
protein catabolic process GO:0030163 162 0.010
regulation of meiosis GO:0040020 94 0.010
regulation of nitrogen compound metabolic process GO:0051171 222 0.010
Human Mouse Fly
regulation of phosphorylation GO:0042325 45 0.010
regulation of cell migration GO:0030334 55 0.010
phagocytosis engulfment GO:0006911 98 0.010
engulfment of apoptotic cell GO:0043652 94 0.010
small molecule biosynthetic process GO:0044283 38 0.010
positive regulation of gene expression GO:0010628 112 0.010
regulation of reproductive process GO:2000241 66 0.010
negative regulation of response to external stimulus GO:0032102 3 0.010
regulation of response to stress GO:0080134 28 0.010
positive regulation of transcription dna templated GO:0045893 102 0.010

hpl-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org