Caenorhabditis elegans

13 known processes

pfs-2 (CELE_R06A4.9)

Protein PFS-2

pfs-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.806
embryo development ending in birth or egg hatching GO:0009792 2992 0.478
regulation of vulval development GO:0040028 248 0.271
negative regulation of vulval development GO:0040027 206 0.187
vulval development GO:0040025 333 0.162
regulation of nematode larval development GO:0061062 260 0.158
post embryonic development GO:0009791 2152 0.132
regulation of post embryonic development GO:0048580 260 0.127
regulation of metabolic process GO:0019222 478 0.121
receptor mediated endocytosis GO:0006898 715 0.110
locomotion GO:0040011 1634 0.106
determination of adult lifespan GO:0008340 812 0.101
organ development GO:0048513 1102 0.094
aging GO:0007568 812 0.093
endocytosis GO:0006897 819 0.091
vesicle mediated transport GO:0016192 852 0.086
negative regulation of biological process GO:0048519 567 0.080
nucleic acid metabolic process GO:0090304 299 0.077
positive regulation of metabolic process GO:0009893 187 0.077
body morphogenesis GO:0010171 620 0.074
cell cycle process GO:0022402 482 0.070
establishment of localization GO:0051234 1171 0.070
meiotic nuclear division GO:0007126 300 0.069
regulation of macromolecule metabolic process GO:0060255 421 0.069
macromolecule localization GO:0033036 771 0.066
gene expression GO:0010467 412 0.066
mitotic cell cycle process GO:1903047 194 0.066
negative regulation of nematode larval development GO:0061064 208 0.061
histone modification GO:0016570 30 0.060
regulation of multicellular organismal process GO:0051239 726 0.060
regulation of developmental growth GO:0048638 389 0.059
molting cycle GO:0042303 281 0.059
negative regulation of post embryonic development GO:0048581 208 0.057
negative regulation of macromolecule metabolic process GO:0010605 229 0.054
post embryonic organ development GO:0048569 336 0.054
regulation of biosynthetic process GO:0009889 189 0.054
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.053
establishment of localization in cell GO:0051649 318 0.053
cell cycle GO:0007049 526 0.053
gamete generation GO:0007276 461 0.052
organic substance catabolic process GO:1901575 294 0.052
maintenance of location GO:0051235 580 0.051
lipid storage GO:0019915 565 0.050
dna duplex unwinding GO:0032508 3 0.048
lipid localization GO:0010876 573 0.047
regulation of biological quality GO:0065008 741 0.046
nucleobase containing compound metabolic process GO:0006139 406 0.046
regulation of cellular metabolic process GO:0031323 305 0.045
organelle organization GO:0006996 783 0.045
macromolecular complex subunit organization GO:0043933 320 0.044
protein metabolic process GO:0019538 422 0.044
regulation of macromolecule biosynthetic process GO:0010556 189 0.043
multicellular organism growth GO:0035264 385 0.041
developmental process involved in reproduction GO:0003006 1165 0.041
rna metabolic process GO:0016070 228 0.040
multicellular organismal reproductive process GO:0048609 815 0.040
positive regulation of cellular metabolic process GO:0031325 178 0.040
covalent chromatin modification GO:0016569 30 0.039
positive regulation of multicellular organismal process GO:0051240 417 0.039
chromosome organization GO:0051276 104 0.039
regulation of rna metabolic process GO:0051252 173 0.039
mrna metabolic process GO:0016071 31 0.038
regulation of growth GO:0040008 409 0.038
sex differentiation GO:0007548 909 0.038
regulation of developmental process GO:0050793 684 0.037
dna metabolic process GO:0006259 74 0.037
single organism localization GO:1902578 518 0.037
negative regulation of multicellular organismal process GO:0051241 236 0.037
cellular protein modification process GO:0006464 207 0.037
signal transduction GO:0007165 317 0.036
multicellular organismal aging GO:0010259 812 0.036
developmental growth GO:0048589 412 0.035
gene silencing GO:0016458 143 0.035
macromolecule modification GO:0043412 218 0.034
negative regulation of metabolic process GO:0009892 240 0.033
nucleobase containing compound biosynthetic process GO:0034654 184 0.032
aromatic compound biosynthetic process GO:0019438 192 0.032
germ cell development GO:0007281 351 0.032
small molecule metabolic process GO:0044281 186 0.031
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.031
regulation of gene expression epigenetic GO:0040029 163 0.031
single organism organelle organization GO:1902589 501 0.031
head development GO:0060322 1 0.030
multi organism reproductive process GO:0044703 867 0.029
posttranscriptional gene silencing by rna GO:0035194 143 0.029
posttranscriptional regulation of gene expression GO:0010608 166 0.029
rna interference GO:0016246 137 0.028
transport GO:0006810 1093 0.028
regulation of multicellular organism growth GO:0040014 373 0.027
multicellular organism reproduction GO:0032504 819 0.027
macromolecule biosynthetic process GO:0009059 250 0.027
regulation of multicellular organismal development GO:2000026 317 0.027
cellular component assembly GO:0022607 293 0.027
cell development GO:0048468 696 0.027
chromatin modification GO:0016568 32 0.026
positive regulation of developmental process GO:0051094 408 0.026
negative regulation of developmental process GO:0051093 227 0.026
positive regulation of gene expression GO:0010628 112 0.026
catabolic process GO:0009056 318 0.025
cellular nitrogen compound catabolic process GO:0044270 119 0.025
cellular localization GO:0051641 360 0.025
positive regulation of developmental growth GO:0048639 354 0.024
biosynthetic process GO:0009058 323 0.024
cellular protein metabolic process GO:0044267 279 0.024
cuticle development GO:0042335 100 0.024
organic substance biosynthetic process GO:1901576 323 0.024
cellular catabolic process GO:0044248 199 0.024
positive regulation of growth GO:0045927 369 0.023
hermaphrodite genitalia development GO:0040035 734 0.023
reproductive structure development GO:0048608 850 0.023
positive regulation of multicellular organism growth GO:0040018 352 0.023
regulation of primary metabolic process GO:0080090 292 0.023
regulation of cellular component organization GO:0051128 248 0.022
regulation of meiosis GO:0040020 94 0.022
regulation of meiotic cell cycle GO:0051445 136 0.022
regulation of gene expression GO:0010468 366 0.021
development of primary sexual characteristics GO:0045137 840 0.021
positive regulation of macromolecule metabolic process GO:0010604 149 0.021
reproductive behavior GO:0019098 387 0.021
growth GO:0040007 562 0.021
cellular nitrogen compound biosynthetic process GO:0044271 192 0.021
cellular biosynthetic process GO:0044249 315 0.020
cellular component movement GO:0006928 388 0.020
protein localization GO:0008104 205 0.019
gonad development GO:0008406 840 0.019
cell division GO:0051301 262 0.019
negative regulation of gene expression GO:0010629 217 0.019
multi organism behavior GO:0051705 389 0.018
dna geometric change GO:0032392 3 0.018
heterocycle catabolic process GO:0046700 119 0.018
purine nucleoside triphosphate metabolic process GO:0009144 87 0.018
gene silencing by rna GO:0031047 143 0.018
secretion by cell GO:0032940 138 0.018
transcription from rna polymerase ii promoter GO:0006366 149 0.017
oviposition GO:0018991 364 0.017
cellular macromolecule biosynthetic process GO:0034645 247 0.017
neurogenesis GO:0022008 236 0.017
protein modification process GO:0036211 207 0.017
regulation of nitrogen compound metabolic process GO:0051171 222 0.017
organonitrogen compound metabolic process GO:1901564 151 0.017
regulation of cell division GO:0051302 142 0.017
transcription dna templated GO:0006351 168 0.017
sexual reproduction GO:0019953 546 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.016
nucleobase containing compound catabolic process GO:0034655 114 0.016
rna catabolic process GO:0006401 21 0.016
aromatic compound catabolic process GO:0019439 116 0.016
female gamete generation GO:0007292 254 0.016
chromatin organization GO:0006325 32 0.016
phagocytosis GO:0006909 115 0.016
regulation of nuclear division GO:0051783 115 0.015
cell proliferation GO:0008283 116 0.015
regulation of chromatin modification GO:1903308 2 0.015
internal peptidyl lysine acetylation GO:0018393 3 0.015
ribosome biogenesis GO:0042254 4 0.015
single organism transport GO:0044765 447 0.015
single organism reproductive process GO:0044702 1196 0.015
secretion GO:0046903 147 0.015
neuron differentiation GO:0030182 217 0.015
signaling GO:0023052 401 0.015
dna repair GO:0006281 23 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
programmed cell death GO:0012501 500 0.015
mrna catabolic process GO:0006402 16 0.014
nucleic acid templated transcription GO:0097659 169 0.014
organic cyclic compound catabolic process GO:1901361 119 0.014
heterocycle biosynthetic process GO:0018130 187 0.014
oogenesis GO:0048477 229 0.014
chromosome segregation GO:0007059 180 0.013
multi organism reproductive behavior GO:0044705 387 0.013
collagen and cuticulin based cuticle development GO:0040002 99 0.013
organelle fission GO:0048285 363 0.013
organic cyclic compound biosynthetic process GO:1901362 195 0.013
multi multicellular organism process GO:0044706 390 0.013
nucleoside monophosphate metabolic process GO:0009123 46 0.013
reproductive system development GO:0061458 850 0.013
regulation of organelle organization GO:0033043 164 0.013
genitalia development GO:0048806 741 0.013
cell fate commitment GO:0045165 139 0.013
positive regulation of biosynthetic process GO:0009891 109 0.013
ribonucleotide metabolic process GO:0009259 99 0.013
rna localization GO:0006403 3 0.012
rrna metabolic process GO:0016072 3 0.012
regulation of cell cycle GO:0051726 194 0.012
nucleobase containing small molecule metabolic process GO:0055086 115 0.012
behavior GO:0007610 527 0.012
purine nucleotide catabolic process GO:0006195 75 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.012
macromolecular complex assembly GO:0065003 193 0.012
sensory organ morphogenesis GO:0090596 2 0.012
posttranscriptional gene silencing GO:0016441 143 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.012
macromolecule catabolic process GO:0009057 202 0.012
peptidyl amino acid modification GO:0018193 58 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.011
carbohydrate derivative metabolic process GO:1901135 141 0.011
regulation of canonical wnt signaling pathway GO:0060828 1 0.011
cellular response to dna damage stimulus GO:0006974 41 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.011
nuclear transcribed mrna catabolic process GO:0000956 15 0.011
rna transport GO:0050658 3 0.011
regulation of transport GO:0051049 91 0.011
multicellular organismal reproductive behavior GO:0033057 384 0.011
organic acid metabolic process GO:0006082 47 0.011
embryonic morphogenesis GO:0048598 152 0.011
meiotic cell cycle GO:0051321 335 0.011
cell death GO:0008219 547 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
cell motility GO:0048870 313 0.011
cellular ketone metabolic process GO:0042180 14 0.010
carboxylic acid metabolic process GO:0019752 34 0.010
g1 s transition of mitotic cell cycle GO:0000082 2 0.010
positive regulation of chromosome organization GO:2001252 2 0.010
regulation of cellular amine metabolic process GO:0033238 0 0.010

pfs-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
disease of cellular proliferation DOID:14566 0 0.017
nervous system disease DOID:863 0 0.014
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.014