Caenorhabditis elegans

50 known processes

cids-2 (CELE_F36A2.1)

Protein CIDS-2

cids-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.927
embryo development GO:0009790 3052 0.863
post embryonic development GO:0009791 2152 0.817
organ development GO:0048513 1102 0.605
reproductive structure development GO:0048608 850 0.581
single organism reproductive process GO:0044702 1196 0.580
developmental process involved in reproduction GO:0003006 1165 0.551
protein metabolic process GO:0019538 422 0.523
cell death GO:0008219 547 0.494
gene expression GO:0010467 412 0.492
nucleic acid metabolic process GO:0090304 299 0.465
multicellular organism reproduction GO:0032504 819 0.455
multicellular organismal reproductive process GO:0048609 815 0.417
regulation of primary metabolic process GO:0080090 292 0.381
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.370
rna metabolic process GO:0016070 228 0.359
organic substance biosynthetic process GO:1901576 323 0.357
regulation of macromolecule metabolic process GO:0060255 421 0.349
positive regulation of cellular process GO:0048522 332 0.331
meiotic nuclear division GO:0007126 300 0.329
development of primary sexual characteristics GO:0045137 840 0.322
cell surface receptor signaling pathway GO:0007166 149 0.306
vulval development GO:0040025 333 0.306
sex differentiation GO:0007548 909 0.304
locomotion GO:0040011 1634 0.303
cellular macromolecule biosynthetic process GO:0034645 247 0.298
negative regulation of metabolic process GO:0009892 240 0.272
negative regulation of macromolecule metabolic process GO:0010605 229 0.265
regulation of vulval development GO:0040028 248 0.264
programmed cell death GO:0012501 500 0.264
gonad development GO:0008406 840 0.262
establishment of localization GO:0051234 1171 0.261
negative regulation of vulval development GO:0040027 206 0.254
germ cell development GO:0007281 351 0.253
single organism localization GO:1902578 518 0.252
gamete generation GO:0007276 461 0.252
microtubule based process GO:0007017 182 0.241
regulation of gene expression GO:0010468 366 0.238
nucleobase containing compound biosynthetic process GO:0034654 184 0.235
protein modification process GO:0036211 207 0.232
reproductive system development GO:0061458 850 0.223
cell development GO:0048468 696 0.219
macromolecule biosynthetic process GO:0009059 250 0.219
apoptotic process GO:0006915 478 0.218
regulation of cytoplasmic transport GO:1903649 3 0.217
ribonucleoprotein complex assembly GO:0022618 4 0.215
cell projection organization GO:0030030 231 0.209
sexual reproduction GO:0019953 546 0.208
chromosome organization GO:0051276 104 0.208
regulation of metabolic process GO:0019222 478 0.208
hermaphrodite genitalia development GO:0040035 734 0.207
regulation of macromolecule biosynthetic process GO:0010556 189 0.207
vesicle mediated transport GO:0016192 852 0.202
post embryonic organ development GO:0048569 336 0.201
genitalia development GO:0048806 741 0.201
neurogenesis GO:0022008 236 0.196
negative regulation of biological process GO:0048519 567 0.192
oviposition GO:0018991 364 0.187
negative regulation of cellular metabolic process GO:0031324 95 0.187
cellular component assembly GO:0022607 293 0.183
regulation of cellular metabolic process GO:0031323 305 0.173
cellular localization GO:0051641 360 0.171
cell cycle process GO:0022402 482 0.168
multi organism reproductive process GO:0044703 867 0.164
nucleobase containing compound metabolic process GO:0006139 406 0.160
cellular protein metabolic process GO:0044267 279 0.159
organic cyclic compound biosynthetic process GO:1901362 195 0.158
regulation of nematode larval development GO:0061062 260 0.158
establishment of localization in cell GO:0051649 318 0.157
rna biosynthetic process GO:0032774 169 0.155
single organism organelle organization GO:1902589 501 0.154
regulation of gene expression epigenetic GO:0040029 163 0.154
axon development GO:0061564 163 0.153
macroautophagy GO:0016236 11 0.153
phosphorus metabolic process GO:0006793 232 0.153
regulation of nitrogen compound metabolic process GO:0051171 222 0.152
cell cycle GO:0007049 526 0.150
death GO:0016265 547 0.146
cell part morphogenesis GO:0032990 152 0.144
regulation of cellular biosynthetic process GO:0031326 189 0.139
biosynthetic process GO:0009058 323 0.139
oogenesis GO:0048477 229 0.138
gene silencing GO:0016458 143 0.137
cellular biosynthetic process GO:0044249 315 0.136
aromatic compound biosynthetic process GO:0019438 192 0.134
macromolecule localization GO:0033036 771 0.132
negative regulation of nematode larval development GO:0061064 208 0.129
single organism cellular localization GO:1902580 72 0.125
macromolecule modification GO:0043412 218 0.125
transcription dna templated GO:0006351 168 0.124
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.120
cellular nitrogen compound biosynthetic process GO:0044271 192 0.119
head development GO:0060322 1 0.116
regulation of multicellular organismal development GO:2000026 317 0.116
nucleic acid templated transcription GO:0097659 169 0.113
regulation of meiotic cell cycle GO:0051445 136 0.113
organic substance catabolic process GO:1901575 294 0.113
posttranscriptional regulation of gene expression GO:0010608 166 0.112
endocytosis GO:0006897 819 0.112
neuron projection development GO:0031175 187 0.112
regulation of rna biosynthetic process GO:2001141 165 0.111
cell morphogenesis GO:0000902 163 0.107
organelle fission GO:0048285 363 0.106
regulation of nucleocytoplasmic transport GO:0046822 3 0.106
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.106
negative regulation of gene expression GO:0010629 217 0.105
posttranscriptional gene silencing GO:0016441 143 0.105
regulation of meiosis GO:0040020 94 0.102
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.100
single organism behavior GO:0044708 83 0.100
negative regulation of multicellular organismal process GO:0051241 236 0.100
macromolecular complex subunit organization GO:0043933 320 0.098
regulation of nucleic acid templated transcription GO:1903506 165 0.097
regulation of rna metabolic process GO:0051252 173 0.093
negative regulation of cellular process GO:0048523 239 0.092
transport GO:0006810 1093 0.091
single organism transport GO:0044765 447 0.089
organelle assembly GO:0070925 214 0.089
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.089
regulation of multicellular organismal process GO:0051239 726 0.088
receptor mediated endocytosis GO:0006898 715 0.088
cell projection morphogenesis GO:0048858 148 0.088
enzyme linked receptor protein signaling pathway GO:0007167 50 0.087
neuron development GO:0048666 199 0.087
regulation of locomotion GO:0040012 161 0.085
gene silencing by rna GO:0031047 143 0.084
neuron projection morphogenesis GO:0048812 114 0.083
nervous system development GO:0007399 253 0.081
neuron projection guidance GO:0097485 82 0.081
neuron differentiation GO:0030182 217 0.081
spindle organization GO:0007051 92 0.080
heterocycle biosynthetic process GO:0018130 187 0.080
meiotic cell cycle GO:0051321 335 0.078
cellular component morphogenesis GO:0032989 318 0.078
regulation of developmental process GO:0050793 684 0.076
cellular component biogenesis GO:0044085 297 0.074
regulation of cell proliferation GO:0042127 105 0.073
regulation of biological quality GO:0065008 741 0.071
organelle organization GO:0006996 783 0.070
aging GO:0007568 812 0.069
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.069
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.068
mitotic spindle organization GO:0007052 81 0.067
transcription from rna polymerase ii promoter GO:0006366 149 0.066
cellular response to endogenous stimulus GO:0071495 32 0.065
rna interference GO:0016246 137 0.065
maintenance of location GO:0051235 580 0.062
purine nucleoside catabolic process GO:0006152 75 0.062
chromatin organization GO:0006325 32 0.062
positive regulation of developmental process GO:0051094 408 0.061
regulation of transcription dna templated GO:0006355 164 0.061
posttranscriptional gene silencing by rna GO:0035194 143 0.061
negative regulation of biosynthetic process GO:0009890 65 0.060
catabolic process GO:0009056 318 0.060
cellular response to chemical stimulus GO:0070887 129 0.060
multicellular organismal aging GO:0010259 812 0.060
protein phosphorylation GO:0006468 85 0.059
lipid localization GO:0010876 573 0.057
negative regulation of cellular biosynthetic process GO:0031327 65 0.057
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.057
positive regulation of cellular metabolic process GO:0031325 178 0.057
cell division GO:0051301 262 0.056
cellular response to dna damage stimulus GO:0006974 41 0.056
rna splicing GO:0008380 8 0.056
muscle structure development GO:0061061 191 0.056
lipid storage GO:0019915 565 0.055
growth GO:0040007 562 0.055
response to chemical GO:0042221 356 0.054
regulation of growth GO:0040008 409 0.053
behavior GO:0007610 527 0.053
protein localization GO:0008104 205 0.052
regulation of cell division GO:0051302 142 0.052
single organism catabolic process GO:0044712 129 0.051
single organism signaling GO:0044700 401 0.050
macromolecular complex assembly GO:0065003 193 0.050
regulation of organelle organization GO:0033043 164 0.050
heterocycle catabolic process GO:0046700 119 0.050
cell proliferation GO:0008283 116 0.049
regulation of cellular component organization GO:0051128 248 0.049
cellular macromolecular complex assembly GO:0034622 184 0.048
cytoskeleton organization GO:0007010 339 0.048
negative regulation of post embryonic development GO:0048581 208 0.047
oocyte construction GO:0007308 2 0.046
determination of adult lifespan GO:0008340 812 0.046
generation of neurons GO:0048699 235 0.045
macromolecule catabolic process GO:0009057 202 0.045
cellular protein modification process GO:0006464 207 0.045
regulation of mitotic cell cycle GO:0007346 76 0.045
mitotic cell cycle process GO:1903047 194 0.044
regulation of nuclear division GO:0051783 115 0.044
response to external stimulus GO:0009605 289 0.043
regulation of post embryonic development GO:0048580 260 0.043
regulation of phosphate metabolic process GO:0019220 81 0.042
regulation of localization GO:0032879 194 0.042
organic substance transport GO:0071702 113 0.041
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.040
digestive tract development GO:0048565 122 0.040
phosphate containing compound metabolic process GO:0006796 232 0.040
muscle cell differentiation GO:0042692 171 0.040
cell morphogenesis involved in differentiation GO:0000904 112 0.040
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.039
small molecule metabolic process GO:0044281 186 0.039
multi organism reproductive behavior GO:0044705 387 0.039
negative regulation of response to stimulus GO:0048585 73 0.039
multi multicellular organism process GO:0044706 390 0.038
phosphorylation GO:0016310 116 0.038
regulation of developmental growth GO:0048638 389 0.037
striated muscle cell differentiation GO:0051146 158 0.037
organonitrogen compound metabolic process GO:1901564 151 0.036
positive regulation of vulval development GO:0040026 52 0.036
secretion GO:0046903 147 0.036
positive regulation of multicellular organism growth GO:0040018 352 0.036
cellular protein complex assembly GO:0043623 178 0.036
axonogenesis GO:0007409 102 0.036
cell cell signaling GO:0007267 118 0.036
negative regulation of cell cycle GO:0045786 53 0.035
cellular catabolic process GO:0044248 199 0.035
multicellular organism growth GO:0035264 385 0.034
cellular protein catabolic process GO:0044257 37 0.034
mitotic nuclear division GO:0007067 89 0.034
regulation of apoptotic process GO:0042981 36 0.034
female gamete generation GO:0007292 254 0.034
regulation of cell cycle process GO:0010564 145 0.033
cellular macromolecule localization GO:0070727 75 0.033
regulation of programmed cell death GO:0043067 50 0.033
regulation of cell death GO:0010941 65 0.033
negative regulation of transcription dna templated GO:0045892 53 0.033
secretion by cell GO:0032940 138 0.033
system process GO:0003008 136 0.033
cell type specific apoptotic process GO:0097285 4 0.032
regulation of biosynthetic process GO:0009889 189 0.032
cell fate commitment GO:0045165 139 0.031
regulation of multicellular organism growth GO:0040014 373 0.031
reproductive behavior GO:0019098 387 0.031
cellular response to organic substance GO:0071310 119 0.031
ribonucleoside monophosphate metabolic process GO:0009161 45 0.030
positive regulation of developmental growth GO:0048639 354 0.030
protein complex subunit organization GO:0071822 280 0.029
cell migration GO:0016477 306 0.029
cellular protein localization GO:0034613 75 0.029
cell motility GO:0048870 313 0.029
tissue development GO:0009888 112 0.028
tube development GO:0035295 126 0.028
multicellular organismal reproductive behavior GO:0033057 384 0.028
oocyte axis specification GO:0007309 2 0.028
establishment of spindle localization GO:0051293 51 0.027
positive regulation of growth GO:0045927 369 0.027
anatomical structure formation involved in morphogenesis GO:0048646 250 0.027
cellular response to stress GO:0033554 162 0.027
regulation of cellular protein metabolic process GO:0032268 75 0.027
positive regulation of metabolic process GO:0009893 187 0.027
negative regulation of signaling GO:0023057 61 0.027
single organism intracellular transport GO:1902582 70 0.026
regulation of signaling GO:0023051 172 0.026
protein complex assembly GO:0006461 186 0.026
regulation of response to stimulus GO:0048583 243 0.026
cellular component movement GO:0006928 388 0.025
positive regulation of gene expression GO:0010628 112 0.025
response to organic substance GO:0010033 131 0.025
organic cyclic compound catabolic process GO:1901361 119 0.025
positive regulation of multicellular organismal process GO:0051240 417 0.025
organ morphogenesis GO:0009887 67 0.025
meiotic cell cycle process GO:1903046 170 0.025
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.025
dna metabolic process GO:0006259 74 0.025
regulation of protein import into nucleus GO:0042306 3 0.024
molting cycle GO:0042303 281 0.024
multi organism behavior GO:0051705 389 0.024
chromatin remodeling GO:0006338 2 0.024
positive regulation of rna biosynthetic process GO:1902680 102 0.024
sister chromatid segregation GO:0000819 46 0.023
ribonucleotide metabolic process GO:0009259 99 0.023
regulation of signal transduction GO:0009966 135 0.023
signaling GO:0023052 401 0.023
digestive system development GO:0055123 122 0.023
modification dependent protein catabolic process GO:0019941 32 0.023
negative regulation of developmental process GO:0051093 227 0.023
establishment of organelle localization GO:0051656 123 0.023
positive regulation of response to stimulus GO:0048584 55 0.023
body morphogenesis GO:0010171 620 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.022
glycosyl compound catabolic process GO:1901658 79 0.022
nucleobase containing compound catabolic process GO:0034655 114 0.022
cellular nitrogen compound catabolic process GO:0044270 119 0.021
ribonucleoside triphosphate metabolic process GO:0009199 87 0.021
regulation of cell differentiation GO:0045595 81 0.021
axon guidance GO:0007411 82 0.021
cytoplasmic transport GO:0016482 23 0.020
neurological system process GO:0050877 53 0.020
negative regulation of signal transduction GO:0009968 60 0.020
vesicle localization GO:0051648 24 0.020
myosin filament assembly GO:0031034 138 0.020
protein modification by small protein conjugation or removal GO:0070647 40 0.020
protein catabolic process GO:0030163 162 0.020
negative regulation of nucleic acid templated transcription GO:1903507 53 0.019
chromosome segregation GO:0007059 180 0.019
organelle localization GO:0051640 127 0.019
protein complex biogenesis GO:0070271 186 0.019
negative regulation of rna metabolic process GO:0051253 53 0.019
protein transport GO:0015031 45 0.019
purine nucleotide metabolic process GO:0006163 95 0.018
signal transduction GO:0007165 317 0.018
regulation of transport GO:0051049 91 0.018
localization of cell GO:0051674 313 0.018
purine ribonucleoside catabolic process GO:0046130 75 0.017
protein ubiquitination GO:0016567 25 0.017
axonal fasciculation GO:0007413 79 0.017
organophosphate metabolic process GO:0019637 125 0.017
positive regulation of signaling GO:0023056 66 0.017
mitotic sister chromatid segregation GO:0000070 38 0.017
positive regulation of cell communication GO:0010647 69 0.017
ribonucleotide catabolic process GO:0009261 75 0.016
carbohydrate derivative metabolic process GO:1901135 141 0.016
intracellular transport GO:0046907 77 0.016
regulation of phosphorylation GO:0042325 45 0.016
developmental growth GO:0048589 412 0.016
ribonucleoside catabolic process GO:0042454 77 0.016
negative regulation of cell cycle g2 m phase transition GO:1902750 1 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.016
oocyte differentiation GO:0009994 45 0.016
negative regulation of rna biosynthetic process GO:1902679 53 0.016
negative regulation of cell communication GO:0010648 61 0.016
regulation of cell communication GO:0010646 176 0.016
modification dependent macromolecule catabolic process GO:0043632 32 0.015
striated muscle cell development GO:0055002 157 0.015
regulation of cellular localization GO:0060341 42 0.015
meiotic chromosome segregation GO:0045132 139 0.015
nucleoside triphosphate catabolic process GO:0009143 72 0.015
histone modification GO:0016570 30 0.015
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.015
nucleoside triphosphate metabolic process GO:0009141 87 0.015
negative regulation of cellular protein metabolic process GO:0032269 27 0.015
regulation of protein targeting GO:1903533 3 0.015
negative regulation of mitotic cell cycle GO:0045930 42 0.015
aromatic compound catabolic process GO:0019439 116 0.015
regulation of apoptotic signaling pathway GO:2001233 1 0.015
chemotaxis GO:0006935 120 0.015
response to extracellular stimulus GO:0009991 38 0.015
proteolysis GO:0006508 61 0.015
nuclear migration GO:0007097 54 0.014
regulation of hydrolase activity GO:0051336 45 0.014
mitotic sister chromatid separation GO:0051306 13 0.014
phagocytosis engulfment GO:0006911 98 0.014
regulation of phosphorus metabolic process GO:0051174 81 0.014
cell cycle phase transition GO:0044770 19 0.014
cellular component assembly involved in morphogenesis GO:0010927 183 0.014
regulation of microtubule cytoskeleton organization GO:0070507 21 0.014
ribonucleoside triphosphate catabolic process GO:0009203 72 0.014
ribonucleoside metabolic process GO:0009119 98 0.013
nucleobase containing small molecule metabolic process GO:0055086 115 0.013
muscle cell development GO:0055001 158 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.013
carbohydrate derivative catabolic process GO:1901136 82 0.013
metaphase plate congression GO:0051310 5 0.013
cellular macromolecule catabolic process GO:0044265 73 0.013
regulation of catalytic activity GO:0050790 78 0.013
establishment or maintenance of cell polarity GO:0007163 63 0.012
positive regulation of nematode larval development GO:0061063 54 0.012
negative regulation of neurogenesis GO:0050768 4 0.012
response to nutrient levels GO:0031667 35 0.012
covalent chromatin modification GO:0016569 30 0.012
polar body extrusion after meiotic divisions GO:0040038 14 0.012
histone h3 acetylation GO:0043966 1 0.012
positive regulation of signal transduction GO:0009967 40 0.012
regulation of protein stability GO:0031647 3 0.012
rna localization GO:0006403 3 0.012
protein modification by small protein conjugation GO:0032446 31 0.012
cellular response to nutrient levels GO:0031669 13 0.012
neuron apoptotic process GO:0051402 4 0.011
response to abiotic stimulus GO:0009628 152 0.011
positive regulation of macromolecule metabolic process GO:0010604 149 0.011
nucleoside phosphate catabolic process GO:1901292 77 0.011
nucleoside catabolic process GO:0009164 78 0.011
regulation of molecular function GO:0065009 89 0.011
sensory organ morphogenesis GO:0090596 2 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
adult locomotory behavior GO:0008344 1 0.011
regulation of cellular component movement GO:0051270 62 0.011
negative regulation of gene expression epigenetic GO:0045814 2 0.011
negative regulation of mitotic metaphase anaphase transition GO:0045841 4 0.011
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 4 0.011
myosin filament organization GO:0031033 138 0.011
cell cycle g2 m phase transition GO:0044839 1 0.010
single organism biosynthetic process GO:0044711 91 0.010
regulation of chromosome organization GO:0033044 20 0.010
membrane invagination GO:0010324 98 0.010
positive regulation of protein transport GO:0051222 4 0.010
chromosome separation GO:0051304 19 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 28 0.010
regulation of sister chromatid segregation GO:0033045 16 0.010
actin cytoskeleton organization GO:0030036 184 0.010
chromatin assembly or disassembly GO:0006333 1 0.010
regulation of microtubule based process GO:0032886 21 0.010
positive regulation of rna metabolic process GO:0051254 103 0.010
rna splicing via transesterification reactions GO:0000375 8 0.010
purine nucleoside metabolic process GO:0042278 92 0.010
response to acid chemical GO:0001101 4 0.010
response to nitrogen compound GO:1901698 25 0.010
oocyte development GO:0048599 44 0.010

cids-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
gastrointestinal system cancer DOID:3119 0 0.015
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
disease of mental health DOID:150 0 0.012