Caenorhabditis elegans

102 known processes

nfi-1 (CELE_ZK1290.4)

Protein NFI-1

nfi-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism reproductive process GO:0044702 1196 0.746
embryo development ending in birth or egg hatching GO:0009792 2992 0.669
multicellular organism reproduction GO:0032504 819 0.545
gamete generation GO:0007276 461 0.479
positive regulation of cellular process GO:0048522 332 0.431
developmental process involved in reproduction GO:0003006 1165 0.410
sexual reproduction GO:0019953 546 0.379
genitalia development GO:0048806 741 0.373
post embryonic development GO:0009791 2152 0.372
nucleic acid templated transcription GO:0097659 169 0.368
post embryonic organ development GO:0048569 336 0.367
locomotion GO:0040011 1634 0.349
regulation of metabolic process GO:0019222 478 0.337
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.325
regulation of rna metabolic process GO:0051252 173 0.324
cell projection morphogenesis GO:0048858 148 0.318
Mouse
germ cell development GO:0007281 351 0.284
taxis GO:0042330 128 0.283
Mouse
cellular biosynthetic process GO:0044249 315 0.275
regulation of primary metabolic process GO:0080090 292 0.273
positive regulation of transcription dna templated GO:0045893 102 0.266
rna biosynthetic process GO:0032774 169 0.266
regulation of cellular metabolic process GO:0031323 305 0.252
vesicle mediated transport GO:0016192 852 0.250
cellular component morphogenesis GO:0032989 318 0.246
Mouse
regulation of cellular biosynthetic process GO:0031326 189 0.245
cell motility GO:0048870 313 0.235
organelle organization GO:0006996 783 0.233
rna metabolic process GO:0016070 228 0.231
cell development GO:0048468 696 0.226
Mouse
vulval development GO:0040025 333 0.213
positive regulation of rna biosynthetic process GO:1902680 102 0.209
negative regulation of nematode larval development GO:0061064 208 0.205
body morphogenesis GO:0010171 620 0.204
regulation of nematode larval development GO:0061062 260 0.201
regulation of vulval development GO:0040028 248 0.201
regulation of gene expression GO:0010468 366 0.200
transport GO:0006810 1093 0.194
aging GO:0007568 812 0.192
negative regulation of vulval development GO:0040027 206 0.191
cellular nitrogen compound biosynthetic process GO:0044271 192 0.188
organ morphogenesis GO:0009887 67 0.186
Mouse
regulation of macromolecule metabolic process GO:0060255 421 0.176
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.175
regulation of locomotion GO:0040012 161 0.174
embryo development GO:0009790 3052 0.170
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.170
protein metabolic process GO:0019538 422 0.169
regulation of nucleic acid templated transcription GO:1903506 165 0.169
cell part morphogenesis GO:0032990 152 0.168
Mouse
single organism organelle organization GO:1902589 501 0.164
cellular protein modification process GO:0006464 207 0.160
nucleobase containing compound biosynthetic process GO:0034654 184 0.159
multicellular organismal reproductive process GO:0048609 815 0.146
cell morphogenesis GO:0000902 163 0.146
Mouse
regulation of response to stimulus GO:0048583 243 0.145
transcription dna templated GO:0006351 168 0.142
gonad development GO:0008406 840 0.140
cell projection organization GO:0030030 231 0.139
Mouse
organ development GO:0048513 1102 0.137
Mouse
gene expression GO:0010467 412 0.136
anatomical structure formation involved in morphogenesis GO:0048646 250 0.134
Mouse
regulation of transcription dna templated GO:0006355 164 0.133
regulation of cellular component organization GO:0051128 248 0.132
response to external stimulus GO:0009605 289 0.130
Mouse
multicellular organismal aging GO:0010259 812 0.128
negative regulation of post embryonic development GO:0048581 208 0.128
defense response GO:0006952 296 0.127
axonogenesis GO:0007409 102 0.125
Mouse
cell migration GO:0016477 306 0.124
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.124
organelle fission GO:0048285 363 0.118
hermaphrodite genitalia development GO:0040035 734 0.116
aromatic compound biosynthetic process GO:0019438 192 0.113
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.111
macromolecule localization GO:0033036 771 0.108
positive regulation of gene expression GO:0010628 112 0.108
negative regulation of biological process GO:0048519 567 0.108
Human Mouse
establishment of localization GO:0051234 1171 0.107
meiotic cell cycle GO:0051321 335 0.106
endocytosis GO:0006897 819 0.106
nucleobase containing compound metabolic process GO:0006139 406 0.105
sex differentiation GO:0007548 909 0.104
development of primary sexual characteristics GO:0045137 840 0.103
regulation of post embryonic development GO:0048580 260 0.103
meiotic nuclear division GO:0007126 300 0.102
response to wounding GO:0009611 4 0.101
macromolecular complex subunit organization GO:0043933 320 0.099
regulation of multicellular organismal process GO:0051239 726 0.098
chemotaxis GO:0006935 120 0.097
Mouse
organic cyclic compound biosynthetic process GO:1901362 195 0.096
cellular component movement GO:0006928 388 0.093
Mouse
negative regulation of metabolic process GO:0009892 240 0.093
Human Mouse
nucleic acid metabolic process GO:0090304 299 0.091
phosphorus metabolic process GO:0006793 232 0.090
oviposition GO:0018991 364 0.090
organic substance catabolic process GO:1901575 294 0.090
organic substance biosynthetic process GO:1901576 323 0.089
regulation of biological quality GO:0065008 741 0.086
positive regulation of rna metabolic process GO:0051254 103 0.086
single organism localization GO:1902578 518 0.083
protein localization GO:0008104 205 0.083
heterocycle biosynthetic process GO:0018130 187 0.082
multi organism reproductive process GO:0044703 867 0.079
regulation of macromolecule biosynthetic process GO:0010556 189 0.079
axon development GO:0061564 163 0.078
Mouse
cellular protein metabolic process GO:0044267 279 0.075
inductive cell migration GO:0040039 145 0.074
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.073
Human Mouse
purine ribonucleotide metabolic process GO:0009150 95 0.073
regulation of nitrogen compound metabolic process GO:0051171 222 0.073
determination of adult lifespan GO:0008340 812 0.072
neuron projection guidance GO:0097485 82 0.071
Mouse
cellular component biogenesis GO:0044085 297 0.071
biosynthetic process GO:0009058 323 0.069
positive regulation of metabolic process GO:0009893 187 0.068
posttranscriptional regulation of gene expression GO:0010608 166 0.067
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.065
regulation of cell migration GO:0030334 55 0.065
generation of neurons GO:0048699 235 0.063
Mouse
multi organism reproductive behavior GO:0044705 387 0.063
regulation of anatomical structure morphogenesis GO:0022603 51 0.062
Mouse
cellular macromolecule biosynthetic process GO:0034645 247 0.061
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.061
axon guidance GO:0007411 82 0.061
Mouse
single organism transport GO:0044765 447 0.061
digestive tract morphogenesis GO:0048546 76 0.058
maintenance of location GO:0051235 580 0.057
phosphate containing compound metabolic process GO:0006796 232 0.057
neuron projection morphogenesis GO:0048812 114 0.054
Mouse
positive regulation of biosynthetic process GO:0009891 109 0.054
protein modification process GO:0036211 207 0.054
localization of cell GO:0051674 313 0.053
head development GO:0060322 1 0.053
Mouse
cell type specific apoptotic process GO:0097285 4 0.053
positive regulation of cell communication GO:0010647 69 0.052
lipid storage GO:0019915 565 0.052
regulation of localization GO:0032879 194 0.051
immune response GO:0006955 192 0.051
positive regulation of nucleic acid templated transcription GO:1903508 102 0.050
multi organism behavior GO:0051705 389 0.050
digestive system development GO:0055123 122 0.050
macromolecule modification GO:0043412 218 0.050
positive regulation of cellular biosynthetic process GO:0031328 109 0.049
negative regulation of developmental process GO:0051093 227 0.049
Mouse
cellular localization GO:0051641 360 0.049
lipid localization GO:0010876 573 0.049
phosphorylation GO:0016310 116 0.048
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.048
Human Mouse
response to biotic stimulus GO:0009607 101 0.048
digestive tract development GO:0048565 122 0.047
meiotic cell cycle process GO:1903046 170 0.046
multicellular organism growth GO:0035264 385 0.045
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.045
heterocycle catabolic process GO:0046700 119 0.045
response to abiotic stimulus GO:0009628 152 0.044
negative regulation of multicellular organismal process GO:0051241 236 0.044
Mouse
tube morphogenesis GO:0035239 79 0.043
positive regulation of signaling GO:0023056 66 0.043
transcription from rna polymerase ii promoter GO:0006366 149 0.043
cell death GO:0008219 547 0.043
organic cyclic compound catabolic process GO:1901361 119 0.043
multicellular organismal reproductive behavior GO:0033057 384 0.042
cell cycle process GO:0022402 482 0.041
regulation of multicellular organismal development GO:2000026 317 0.041
Mouse
female gamete generation GO:0007292 254 0.041
reproductive structure development GO:0048608 850 0.041
organonitrogen compound metabolic process GO:1901564 151 0.041
carboxylic acid metabolic process GO:0019752 34 0.040
receptor mediated endocytosis GO:0006898 715 0.039
positive regulation of multicellular organismal process GO:0051240 417 0.039
regulation of phosphorus metabolic process GO:0051174 81 0.038
positive regulation of developmental process GO:0051094 408 0.038
positive regulation of macromolecule metabolic process GO:0010604 149 0.038
oogenesis GO:0048477 229 0.038
negative regulation of cellular biosynthetic process GO:0031327 65 0.037
Human Mouse
protein phosphorylation GO:0006468 85 0.037
positive regulation of cellular metabolic process GO:0031325 178 0.037
cellular catabolic process GO:0044248 199 0.037
regulation of mitotic cell cycle GO:0007346 76 0.036
response to other organism GO:0051707 101 0.036
growth GO:0040007 562 0.036
cell cycle GO:0007049 526 0.036
regulation of cellular component movement GO:0051270 62 0.036
single organism cellular localization GO:1902580 72 0.035
spermatogenesis GO:0007283 41 0.035
sensory organ morphogenesis GO:0090596 2 0.035
regulation of cytoplasmic transport GO:1903649 3 0.035
positive regulation of multicellular organism growth GO:0040018 352 0.034
regulation of cell motility GO:2000145 57 0.034
negative regulation of gene expression GO:0010629 217 0.034
Human Mouse
tube development GO:0035295 126 0.034
Mouse
regulation of rna biosynthetic process GO:2001141 165 0.033
purine ribonucleoside catabolic process GO:0046130 75 0.033
neuron differentiation GO:0030182 217 0.033
Mouse
purine nucleoside metabolic process GO:0042278 92 0.033
neuron projection development GO:0031175 187 0.033
Mouse
regulation of nucleocytoplasmic transport GO:0046822 3 0.032
carbohydrate derivative metabolic process GO:1901135 141 0.032
regulation of signal transduction GO:0009966 135 0.032
positive regulation of nematode larval development GO:0061063 54 0.032
negative regulation of macromolecule metabolic process GO:0010605 229 0.032
Human Mouse
death GO:0016265 547 0.031
embryonic morphogenesis GO:0048598 152 0.031
regulation of response to wounding GO:1903034 1 0.031
positive regulation of phosphate metabolic process GO:0045937 56 0.031
reproductive system development GO:0061458 850 0.031
nucleoside triphosphate metabolic process GO:0009141 87 0.031
organophosphate metabolic process GO:0019637 125 0.029
regulation of biosynthetic process GO:0009889 189 0.029
behavior GO:0007610 527 0.029
organophosphate catabolic process GO:0046434 81 0.028
establishment of localization in cell GO:0051649 318 0.028
regulation of multicellular organism growth GO:0040014 373 0.028
protein complex subunit organization GO:0071822 280 0.028
positive regulation of neurogenesis GO:0050769 4 0.028
apoptotic process GO:0006915 478 0.028
catabolic process GO:0009056 318 0.028
covalent chromatin modification GO:0016569 30 0.028
neurogenesis GO:0022008 236 0.027
Mouse
response to chemical GO:0042221 356 0.027
Mouse
regulation of developmental growth GO:0048638 389 0.027
neuron development GO:0048666 199 0.027
Mouse
regulation of organelle organization GO:0033043 164 0.027
signaling GO:0023052 401 0.027
cell recognition GO:0008037 85 0.026
positive regulation of phosphorus metabolic process GO:0010562 56 0.026
small molecule metabolic process GO:0044281 186 0.026
multi multicellular organism process GO:0044706 390 0.026
cytoskeleton organization GO:0007010 339 0.026
phagocytosis GO:0006909 115 0.025
single organism biosynthetic process GO:0044711 91 0.025
nervous system development GO:0007399 253 0.025
Mouse
response to organic substance GO:0010033 131 0.025
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.025
Mouse
regulation of molecular function GO:0065009 89 0.025
Human
cellular response to chemical stimulus GO:0070887 129 0.025
cytoskeleton dependent cytokinesis GO:0061640 35 0.025
cell morphogenesis involved in differentiation GO:0000904 112 0.024
Mouse
embryonic pattern specification GO:0009880 21 0.024
positive regulation of developmental growth GO:0048639 354 0.024
cellular lipid metabolic process GO:0044255 40 0.024
cell division GO:0051301 262 0.024
positive regulation of phosphorylation GO:0042327 27 0.024
aromatic compound catabolic process GO:0019439 116 0.023
reproductive behavior GO:0019098 387 0.023
regulation of protein metabolic process GO:0051246 81 0.023
cellular component assembly GO:0022607 293 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.023
positive regulation of response to stimulus GO:0048584 55 0.023
regulation of developmental process GO:0050793 684 0.022
Mouse
macromolecule catabolic process GO:0009057 202 0.022
positive regulation of molecular function GO:0044093 61 0.022
regulation of protein stability GO:0031647 3 0.022
gastrulation GO:0007369 58 0.022
cell surface receptor signaling pathway GO:0007166 149 0.022
dendrite development GO:0016358 42 0.022
regulation of growth GO:0040008 409 0.022
chromosome segregation GO:0007059 180 0.021
oocyte differentiation GO:0009994 45 0.021
developmental growth GO:0048589 412 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
cellular response to abiotic stimulus GO:0071214 4 0.021
positive regulation of growth GO:0045927 369 0.020
cellular protein localization GO:0034613 75 0.020
cellular component assembly involved in morphogenesis GO:0010927 183 0.020
oxoacid metabolic process GO:0043436 47 0.020
canonical wnt signaling pathway GO:0060070 3 0.020
amine metabolic process GO:0009308 15 0.020
response to external biotic stimulus GO:0043207 101 0.020
regulation of protein localization GO:0032880 50 0.020
nucleobase containing compound catabolic process GO:0034655 114 0.020
organelle assembly GO:0070925 214 0.019
intracellular receptor signaling pathway GO:0030522 2 0.019
regulation of phosphate metabolic process GO:0019220 81 0.019
peptidyl amino acid modification GO:0018193 58 0.019
nucleoside phosphate metabolic process GO:0006753 108 0.019
programmed cell death GO:0012501 500 0.019
pattern specification process GO:0007389 59 0.019
neuron recognition GO:0008038 83 0.019
regulation of transport GO:0051049 91 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
response to temperature stimulus GO:0009266 66 0.019
cellular nitrogen compound catabolic process GO:0044270 119 0.019
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.018
cell adhesion GO:0007155 21 0.018
regulation of cell cycle GO:0051726 194 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.018
macromolecular complex assembly GO:0065003 193 0.018
protein complex assembly GO:0006461 186 0.017
signal transduction GO:0007165 317 0.017
regulation of cell communication GO:0010646 176 0.017
axis specification GO:0009798 23 0.017
microtubule based process GO:0007017 182 0.017
apoptotic cell clearance GO:0043277 111 0.017
internal peptidyl lysine acetylation GO:0018393 3 0.017
histone modification GO:0016570 30 0.016
dorsal ventral axon guidance GO:0033563 19 0.016
single organism catabolic process GO:0044712 129 0.016
chromosome organization GO:0051276 104 0.016
adult behavior GO:0030534 3 0.016
positive regulation of intracellular protein transport GO:0090316 2 0.016
organic acid metabolic process GO:0006082 47 0.016
phagocytosis engulfment GO:0006911 98 0.016
muscle cell differentiation GO:0042692 171 0.015
purine nucleotide catabolic process GO:0006195 75 0.015
cellular ketone metabolic process GO:0042180 14 0.015
nucleobase containing small molecule metabolic process GO:0055086 115 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.015
Human Mouse
male gamete generation GO:0048232 41 0.015
innate immune response GO:0045087 190 0.015
cellular response to stress GO:0033554 162 0.015
regulation of cell proliferation GO:0042127 105 0.015
Mouse
actin filament based process GO:0030029 191 0.015
ribose phosphate metabolic process GO:0019693 99 0.015
negative regulation of transcription dna templated GO:0045892 53 0.015
Human Mouse
single organism behavior GO:0044708 83 0.015
regulation of chromatin modification GO:1903308 2 0.015
organonitrogen compound catabolic process GO:1901565 90 0.015
epithelial tube morphogenesis GO:0060562 1 0.015
positive regulation of neuron projection development GO:0010976 4 0.015
intracellular transport GO:0046907 77 0.014
small gtpase mediated signal transduction GO:0007264 32 0.014
regulation of cell death GO:0010941 65 0.014
muscle structure development GO:0061061 191 0.014
actin cytoskeleton organization GO:0030036 184 0.014
cell proliferation GO:0008283 116 0.014
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 87 0.014
male anatomical structure morphogenesis GO:0090598 78 0.014
regeneration GO:0031099 4 0.014
positive regulation of signal transduction GO:0009967 40 0.014
nucleoside triphosphate catabolic process GO:0009143 72 0.014
posttranscriptional gene silencing by rna GO:0035194 143 0.013
cellular macromolecule localization GO:0070727 75 0.013
ribonucleoside catabolic process GO:0042454 77 0.013
chromatin modification GO:0016568 32 0.013
ribonucleotide metabolic process GO:0009259 99 0.013
gene silencing by rna GO:0031047 143 0.013
oocyte axis specification GO:0007309 2 0.013
cellular amino acid metabolic process GO:0006520 15 0.013
negative regulation of nucleic acid templated transcription GO:1903507 53 0.013
Human Mouse
rna interference GO:0016246 137 0.013
single organism signaling GO:0044700 401 0.013
striated muscle cell differentiation GO:0051146 158 0.013
chromatin remodeling GO:0006338 2 0.013
cell fate commitment GO:0045165 139 0.013
dauer larval development GO:0040024 92 0.013
regulation of cell morphogenesis GO:0022604 40 0.013
organism emergence from protective structure GO:0071684 48 0.013
chromatin organization GO:0006325 32 0.012
positive regulation of mapk cascade GO:0043410 14 0.012
regulation of signaling GO:0023051 172 0.012
ribonucleoside triphosphate metabolic process GO:0009199 87 0.012
cellular amine metabolic process GO:0044106 15 0.012
regulation of cellular localization GO:0060341 42 0.012
positive regulation of gtp catabolic process GO:0033126 28 0.012
nucleoside metabolic process GO:0009116 99 0.012
organic substance transport GO:0071702 113 0.012
ras protein signal transduction GO:0007265 31 0.012
lipid metabolic process GO:0006629 77 0.012
regulation of ras protein signal transduction GO:0046578 41 0.012
regulation of neurogenesis GO:0050767 40 0.012
axonal fasciculation GO:0007413 79 0.012
regulation of epithelial cell proliferation GO:0050678 1 0.011
Mouse
rna processing GO:0006396 34 0.011
positive regulation of cell migration GO:0030335 3 0.011
negative regulation of rna biosynthetic process GO:1902679 53 0.011
Human Mouse
posttranscriptional gene silencing GO:0016441 143 0.011
protein catabolic process GO:0030163 162 0.011
regulation of catabolic process GO:0009894 57 0.011
regulation of multi organism process GO:0043900 69 0.011
epithelial cell proliferation GO:0050673 1 0.011
Mouse
nucleoside phosphate catabolic process GO:1901292 77 0.011
internal protein amino acid acetylation GO:0006475 3 0.011
molting cycle GO:0042303 281 0.011
regulation of neuron projection development GO:0010975 31 0.011
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.010
ribonucleotide catabolic process GO:0009261 75 0.010
regulation of nucleoside metabolic process GO:0009118 37 0.010
regulation of cell development GO:0060284 49 0.010
positive regulation of intracellular transport GO:0032388 2 0.010
purine containing compound metabolic process GO:0072521 95 0.010
regulation of cellular catabolic process GO:0031329 51 0.010
meiosis i GO:0007127 19 0.010
mrna processing GO:0006397 13 0.010
regionalization GO:0003002 31 0.010
actomyosin structure organization GO:0031032 154 0.010
protein complex biogenesis GO:0070271 186 0.010

nfi-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.011