Caenorhabditis elegans

22 known processes

cars-1 (CELE_Y23H5A.7)

Protein CARS-1

cars-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.830
embryo development ending in birth or egg hatching GO:0009792 2992 0.824
organ development GO:0048513 1102 0.471
developmental process involved in reproduction GO:0003006 1165 0.409
reproductive system development GO:0061458 850 0.382
gene expression GO:0010467 412 0.346
protein metabolic process GO:0019538 422 0.338
regulation of gene expression GO:0010468 366 0.303
establishment of localization GO:0051234 1171 0.287
cellular protein metabolic process GO:0044267 279 0.272
gonad development GO:0008406 840 0.262
macromolecule biosynthetic process GO:0009059 250 0.261
sex differentiation GO:0007548 909 0.258
meiotic nuclear division GO:0007126 300 0.247
cellular macromolecule biosynthetic process GO:0034645 247 0.230
multicellular organismal reproductive process GO:0048609 815 0.215
transport GO:0006810 1093 0.214
rna metabolic process GO:0016070 228 0.208
post embryonic development GO:0009791 2152 0.207
single organism reproductive process GO:0044702 1196 0.204
regulation of biosynthetic process GO:0009889 189 0.200
cell cycle GO:0007049 526 0.191
biosynthetic process GO:0009058 323 0.173
multicellular organism reproduction GO:0032504 819 0.164
positive regulation of biosynthetic process GO:0009891 109 0.164
cell death GO:0008219 547 0.162
hermaphrodite genitalia development GO:0040035 734 0.162
multicellular organismal aging GO:0010259 812 0.159
locomotion GO:0040011 1634 0.159
regulation of macromolecule metabolic process GO:0060255 421 0.158
nervous system development GO:0007399 253 0.154
meiotic cell cycle GO:0051321 335 0.153
chromosome organization GO:0051276 104 0.152
sexual reproduction GO:0019953 546 0.151
negative regulation of macromolecule metabolic process GO:0010605 229 0.150
vesicle mediated transport GO:0016192 852 0.150
regulation of cellular biosynthetic process GO:0031326 189 0.149
reproductive structure development GO:0048608 850 0.146
positive regulation of macromolecule metabolic process GO:0010604 149 0.143
regulation of organelle organization GO:0033043 164 0.143
negative regulation of gene expression GO:0010629 217 0.142
regulation of rna biosynthetic process GO:2001141 165 0.139
cell development GO:0048468 696 0.136
nucleobase containing compound metabolic process GO:0006139 406 0.132
cellular biosynthetic process GO:0044249 315 0.132
gamete generation GO:0007276 461 0.130
death GO:0016265 547 0.128
endocytosis GO:0006897 819 0.127
multi organism reproductive process GO:0044703 867 0.122
chromatin organization GO:0006325 32 0.122
regulation of metabolic process GO:0019222 478 0.117
positive regulation of nucleic acid templated transcription GO:1903508 102 0.117
neuron differentiation GO:0030182 217 0.116
nucleic acid metabolic process GO:0090304 299 0.115
regulation of meiotic cell cycle GO:0051445 136 0.115
determination of adult lifespan GO:0008340 812 0.114
organic substance biosynthetic process GO:1901576 323 0.108
regulation of primary metabolic process GO:0080090 292 0.107
organic substance catabolic process GO:1901575 294 0.106
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.104
regulation of macromolecule biosynthetic process GO:0010556 189 0.103
macromolecule modification GO:0043412 218 0.099
neurogenesis GO:0022008 236 0.098
regulation of nuclear division GO:0051783 115 0.098
macromolecule localization GO:0033036 771 0.095
cellular protein modification process GO:0006464 207 0.095
posttranscriptional regulation of gene expression GO:0010608 166 0.091
genitalia development GO:0048806 741 0.091
regulation of cellular metabolic process GO:0031323 305 0.091
multi multicellular organism process GO:0044706 390 0.090
positive regulation of transcription dna templated GO:0045893 102 0.089
negative regulation of biological process GO:0048519 567 0.089
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.088
aging GO:0007568 812 0.088
organelle organization GO:0006996 783 0.088
development of primary sexual characteristics GO:0045137 840 0.087
regulation of rna metabolic process GO:0051252 173 0.084
aromatic compound biosynthetic process GO:0019438 192 0.083
body morphogenesis GO:0010171 620 0.083
regulation of meiosis GO:0040020 94 0.082
regulation of biological quality GO:0065008 741 0.082
cellular component assembly GO:0022607 293 0.081
nucleobase containing compound biosynthetic process GO:0034654 184 0.081
regulation of nitrogen compound metabolic process GO:0051171 222 0.080
cellular component biogenesis GO:0044085 297 0.079
cell migration GO:0016477 306 0.078
generation of neurons GO:0048699 235 0.077
regulation of nucleic acid templated transcription GO:1903506 165 0.076
protein modification process GO:0036211 207 0.076
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.075
heterocycle biosynthetic process GO:0018130 187 0.074
positive regulation of cellular metabolic process GO:0031325 178 0.074
cell projection organization GO:0030030 231 0.073
chromosome segregation GO:0007059 180 0.073
regulation of cellular component organization GO:0051128 248 0.071
macromolecular complex subunit organization GO:0043933 320 0.070
positive regulation of gene expression GO:0010628 112 0.069
cellular response to stress GO:0033554 162 0.068
positive regulation of rna biosynthetic process GO:1902680 102 0.068
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.067
maintenance of location GO:0051235 580 0.065
multi organism reproductive behavior GO:0044705 387 0.065
lipid localization GO:0010876 573 0.064
regulation of cellular protein metabolic process GO:0032268 75 0.064
germ cell development GO:0007281 351 0.064
catabolic process GO:0009056 318 0.064
receptor mediated endocytosis GO:0006898 715 0.063
lipid storage GO:0019915 565 0.062
cellular catabolic process GO:0044248 199 0.062
negative regulation of biosynthetic process GO:0009890 65 0.061
negative regulation of developmental process GO:0051093 227 0.061
apoptotic process GO:0006915 478 0.061
multicellular organismal reproductive behavior GO:0033057 384 0.060
regulation of multicellular organismal development GO:2000026 317 0.059
organelle fission GO:0048285 363 0.059
positive regulation of metabolic process GO:0009893 187 0.059
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.058
macromolecule catabolic process GO:0009057 202 0.058
single organism localization GO:1902578 518 0.057
regulation of cell cycle process GO:0010564 145 0.057
oviposition GO:0018991 364 0.057
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.055
multi organism behavior GO:0051705 389 0.055
heterocycle catabolic process GO:0046700 119 0.055
regulation of cell division GO:0051302 142 0.054
growth GO:0040007 562 0.054
rrna metabolic process GO:0016072 3 0.053
protein catabolic process GO:0030163 162 0.053
regulation of growth GO:0040008 409 0.053
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.053
behavior GO:0007610 527 0.051
dna metabolic process GO:0006259 74 0.050
reproductive behavior GO:0019098 387 0.050
positive regulation of cellular biosynthetic process GO:0031328 109 0.050
aromatic compound catabolic process GO:0019439 116 0.049
head development GO:0060322 1 0.047
meiotic chromosome segregation GO:0045132 139 0.047
nucleic acid templated transcription GO:0097659 169 0.047
cellular nitrogen compound biosynthetic process GO:0044271 192 0.046
female gamete generation GO:0007292 254 0.045
cellular macromolecular complex assembly GO:0034622 184 0.044
programmed cell death GO:0012501 500 0.044
regulation of transcription dna templated GO:0006355 164 0.043
negative regulation of metabolic process GO:0009892 240 0.043
organic cyclic compound biosynthetic process GO:1901362 195 0.042
multicellular organism growth GO:0035264 385 0.042
cellular protein complex assembly GO:0043623 178 0.042
rna biosynthetic process GO:0032774 169 0.042
cell cycle process GO:0022402 482 0.041
positive regulation of multicellular organism growth GO:0040018 352 0.040
regulation of multicellular organismal process GO:0051239 726 0.040
defense response GO:0006952 296 0.040
positive regulation of cellular process GO:0048522 332 0.040
positive regulation of growth GO:0045927 369 0.039
regulation of developmental growth GO:0048638 389 0.038
protein complex subunit organization GO:0071822 280 0.038
neuron projection development GO:0031175 187 0.038
oogenesis GO:0048477 229 0.037
single organism organelle organization GO:1902589 501 0.037
nucleoside phosphate metabolic process GO:0006753 108 0.037
single organism catabolic process GO:0044712 129 0.036
developmental growth GO:0048589 412 0.036
positive regulation of rna metabolic process GO:0051254 103 0.036
cell recognition GO:0008037 85 0.036
neuron development GO:0048666 199 0.036
nucleobase containing compound catabolic process GO:0034655 114 0.036
response to external stimulus GO:0009605 289 0.036
anatomical structure formation involved in morphogenesis GO:0048646 250 0.036
transcription from rna polymerase ii promoter GO:0006366 149 0.035
response to abiotic stimulus GO:0009628 152 0.035
negative regulation of cellular biosynthetic process GO:0031327 65 0.035
membrane organization GO:0061024 135 0.035
regulation of multicellular organism growth GO:0040014 373 0.035
cell division GO:0051301 262 0.035
organic cyclic compound catabolic process GO:1901361 119 0.035
macromolecular complex assembly GO:0065003 193 0.034
response to chemical GO:0042221 356 0.034
transcription dna templated GO:0006351 168 0.034
actomyosin structure organization GO:0031032 154 0.033
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.032
cellular nitrogen compound catabolic process GO:0044270 119 0.032
rna localization GO:0006403 3 0.030
regulation of vulval development GO:0040028 248 0.030
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.029
regulation of gene expression epigenetic GO:0040029 163 0.029
negative regulation of post embryonic development GO:0048581 208 0.029
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.029
histone modification GO:0016570 30 0.029
chromatin modification GO:0016568 32 0.028
protein complex biogenesis GO:0070271 186 0.028
cellular component morphogenesis GO:0032989 318 0.028
covalent chromatin modification GO:0016569 30 0.028
cellular component movement GO:0006928 388 0.028
negative regulation of cellular metabolic process GO:0031324 95 0.028
axon development GO:0061564 163 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.028
actin cytoskeleton organization GO:0030036 184 0.027
meiotic cell cycle process GO:1903046 170 0.027
cytoskeleton organization GO:0007010 339 0.027
negative regulation of nematode larval development GO:0061064 208 0.027
single organism signaling GO:0044700 401 0.027
signaling GO:0023052 401 0.027
phosphorus metabolic process GO:0006793 232 0.027
engulfment of apoptotic cell GO:0043652 94 0.026
positive regulation of multicellular organismal process GO:0051240 417 0.026
sensory organ morphogenesis GO:0090596 2 0.026
embryonic morphogenesis GO:0048598 152 0.026
vulval development GO:0040025 333 0.026
negative regulation of multicellular organismal process GO:0051241 236 0.026
single organism transport GO:0044765 447 0.026
post embryonic organ development GO:0048569 336 0.026
regulation of developmental process GO:0050793 684 0.025
posttranscriptional gene silencing GO:0016441 143 0.025
immune response GO:0006955 192 0.024
actin filament based process GO:0030029 191 0.024
gene silencing GO:0016458 143 0.024
positive regulation of developmental growth GO:0048639 354 0.024
regulation of protein metabolic process GO:0051246 81 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.024
regulation of cell cycle GO:0051726 194 0.024
translation GO:0006412 37 0.024
chromosome organization involved in meiosis GO:0070192 25 0.023
regulation of post embryonic development GO:0048580 260 0.023
purine ribonucleotide catabolic process GO:0009154 75 0.023
organelle assembly GO:0070925 214 0.022
cell proliferation GO:0008283 116 0.022
phagocytosis GO:0006909 115 0.022
rna catabolic process GO:0006401 21 0.022
neuron recognition GO:0008038 83 0.022
negative regulation of gene expression epigenetic GO:0045814 2 0.022
collagen and cuticulin based cuticle development GO:0040002 99 0.022
ncrna metabolic process GO:0034660 14 0.021
muscle structure development GO:0061061 191 0.021
nucleotide metabolic process GO:0009117 108 0.021
negative regulation of rna metabolic process GO:0051253 53 0.021
regulation of synapse assembly GO:0051963 2 0.021
apoptotic cell clearance GO:0043277 111 0.021
regulation of nematode larval development GO:0061062 260 0.021
purine containing compound metabolic process GO:0072521 95 0.021
glycosyl compound metabolic process GO:1901657 100 0.020
response to organic substance GO:0010033 131 0.020
molting cycle GO:0042303 281 0.020
guanosine containing compound metabolic process GO:1901068 49 0.020
fertilization GO:0009566 63 0.019
positive regulation of neurogenesis GO:0050769 4 0.019
nucleobase containing small molecule metabolic process GO:0055086 115 0.019
sister chromatid segregation GO:0000819 46 0.019
tube development GO:0035295 126 0.019
ribonucleoside metabolic process GO:0009119 98 0.019
translational initiation GO:0006413 2 0.019
positive regulation of developmental process GO:0051094 408 0.019
posttranscriptional gene silencing by rna GO:0035194 143 0.019
mitotic sister chromatid segregation GO:0000070 38 0.019
digestive tract morphogenesis GO:0048546 76 0.018
small molecule metabolic process GO:0044281 186 0.018
gastrulation GO:0007369 58 0.018
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.018
gene silencing by rna GO:0031047 143 0.018
cellular response to chemical stimulus GO:0070887 129 0.018
digestive system development GO:0055123 122 0.018
response to external biotic stimulus GO:0043207 101 0.018
neuromuscular junction development GO:0007528 2 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.018
organophosphate catabolic process GO:0046434 81 0.018
regulation of cell proliferation GO:0042127 105 0.017
cellular macromolecule catabolic process GO:0044265 73 0.017
myosin filament organization GO:0031033 138 0.017
defense response to bacterium GO:0042742 86 0.017
signal transduction GO:0007165 317 0.017
purine nucleotide metabolic process GO:0006163 95 0.017
ribonucleotide metabolic process GO:0009259 99 0.017
cellular localization GO:0051641 360 0.017
establishment of organelle localization GO:0051656 123 0.017
glycosyl compound catabolic process GO:1901658 79 0.017
guanosine containing compound catabolic process GO:1901069 48 0.017
tissue development GO:0009888 112 0.017
regulation of signal transduction GO:0009966 135 0.017
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.017
striated muscle myosin thick filament assembly GO:0071688 138 0.016
response to other organism GO:0051707 101 0.016
transmembrane transport GO:0055085 110 0.016
proteolysis GO:0006508 61 0.016
organophosphate metabolic process GO:0019637 125 0.016
regulation of apoptotic signaling pathway GO:2001233 1 0.016
nucleoside metabolic process GO:0009116 99 0.016
axonal fasciculation GO:0007413 79 0.016
membrane invagination GO:0010324 98 0.016
rna interference GO:0016246 137 0.016
organonitrogen compound metabolic process GO:1901564 151 0.016
cellular protein catabolic process GO:0044257 37 0.016
ribonucleoside catabolic process GO:0042454 77 0.016
cellular response to dna damage stimulus GO:0006974 41 0.016
adult behavior GO:0030534 3 0.016
purine nucleoside triphosphate metabolic process GO:0009144 87 0.015
cell morphogenesis GO:0000902 163 0.015
organonitrogen compound catabolic process GO:1901565 90 0.015
phosphate containing compound metabolic process GO:0006796 232 0.015
ribonucleotide catabolic process GO:0009261 75 0.015
ribonucleoside triphosphate catabolic process GO:0009203 72 0.015
protein folding GO:0006457 7 0.015
ribonucleoside triphosphate metabolic process GO:0009199 87 0.015
synaptonemal complex organization GO:0070193 8 0.015
response to bacterium GO:0009617 86 0.015
negative regulation of vulval development GO:0040027 206 0.015
purine containing compound catabolic process GO:0072523 75 0.015
positive regulation of cellular component organization GO:0051130 34 0.014
cell motility GO:0048870 313 0.014
cell morphogenesis involved in differentiation GO:0000904 112 0.014
male sex differentiation GO:0046661 86 0.014
myosin filament assembly GO:0031034 138 0.014
modification dependent macromolecule catabolic process GO:0043632 32 0.014
chromatin remodeling GO:0006338 2 0.014
negative regulation of nucleic acid templated transcription GO:1903507 53 0.014
cleavage involved in rrna processing GO:0000469 2 0.014
protein localization GO:0008104 205 0.014
response to biotic stimulus GO:0009607 101 0.014
cellular component assembly involved in morphogenesis GO:0010927 183 0.014
localization of cell GO:0051674 313 0.014
dna repair GO:0006281 23 0.014
regulation of cell morphogenesis GO:0022604 40 0.014
regulation of cellular component biogenesis GO:0044087 26 0.014
regulation of molecular function GO:0065009 89 0.013
defense response to gram negative bacterium GO:0050829 64 0.013
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 1 0.013
negative regulation of rna biosynthetic process GO:1902679 53 0.013
protein complex assembly GO:0006461 186 0.013
organic acid metabolic process GO:0006082 47 0.013
gtp metabolic process GO:0046039 46 0.013
mitotic cell cycle process GO:1903047 194 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.013
muscle cell development GO:0055001 158 0.013
cuticle development GO:0042335 100 0.013
purine ribonucleoside catabolic process GO:0046130 75 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
neuron projection morphogenesis GO:0048812 114 0.013
striated muscle cell differentiation GO:0051146 158 0.013
nucleoside triphosphate metabolic process GO:0009141 87 0.013
nematode male tail tip morphogenesis GO:0045138 77 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
meiosis i GO:0007127 19 0.012
single fertilization GO:0007338 61 0.012
phagocytosis engulfment GO:0006911 98 0.012
cell type specific apoptotic process GO:0097285 4 0.012
nucleotide catabolic process GO:0009166 77 0.012
male anatomical structure morphogenesis GO:0090598 78 0.012
purine nucleotide catabolic process GO:0006195 75 0.012
synapsis GO:0007129 10 0.012
muscle cell differentiation GO:0042692 171 0.012
nucleoside triphosphate catabolic process GO:0009143 72 0.012
regulation of protein targeting GO:1903533 3 0.012
carbohydrate derivative metabolic process GO:1901135 141 0.012
cellular amino acid metabolic process GO:0006520 15 0.011
myofibril assembly GO:0030239 154 0.011
modification dependent protein catabolic process GO:0019941 32 0.011
response to wounding GO:0009611 4 0.011
positive regulation of intracellular transport GO:0032388 2 0.011
regulation of protein import into nucleus GO:0042306 3 0.011
negative regulation of neurogenesis GO:0050768 4 0.011
negative regulation of protein metabolic process GO:0051248 27 0.011
regulation of neurogenesis GO:0050767 40 0.011
spermatogenesis GO:0007283 41 0.011
regulation of bmp signaling pathway GO:0030510 3 0.011
nucleoside catabolic process GO:0009164 78 0.011
response to temperature stimulus GO:0009266 66 0.011
cellular response to abiotic stimulus GO:0071214 4 0.011
dna templated transcription initiation GO:0006352 3 0.011
chromatin assembly or disassembly GO:0006333 1 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.010
purine ribonucleoside metabolic process GO:0046128 92 0.010
regulation of reproductive process GO:2000241 66 0.010
striated muscle cell development GO:0055002 157 0.010
cellular macromolecule localization GO:0070727 75 0.010
positive regulation of intracellular signal transduction GO:1902533 24 0.010
innate immune response GO:0045087 190 0.010
carbohydrate derivative catabolic process GO:1901136 82 0.010
nucleoside phosphate catabolic process GO:1901292 77 0.010

cars-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
disease of metabolism DOID:0014667 0 0.014
nervous system disease DOID:863 0 0.012
neuromuscular disease DOID:440 0 0.011
charcot marie tooth disease type 2 DOID:0050539 0 0.011
charcot marie tooth disease DOID:10595 0 0.011
neuropathy DOID:870 0 0.011