Caenorhabditis elegans

136 known processes

pmk-1 (CELE_B0218.3)

Protein PMK-1

pmk-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell cycle process GO:0022402 482 0.849
Yeast Mouse
sexual reproduction GO:0019953 546 0.848
Yeast Worm
cell cycle GO:0007049 526 0.821
Yeast Mouse Rat Worm
multicellular organism reproduction GO:0032504 819 0.815
Worm
organelle organization GO:0006996 783 0.750
Worm
transport GO:0006810 1093 0.704
Mouse Worm
signaling GO:0023052 401 0.701
developmental process involved in reproduction GO:0003006 1165 0.692
Yeast Worm
regulation of cellular metabolic process GO:0031323 305 0.673
multi organism reproductive process GO:0044703 867 0.670
Yeast Worm
multicellular organismal reproductive process GO:0048609 815 0.657
Worm
regulation of transcription dna templated GO:0006355 164 0.651
regulation of multicellular organismal process GO:0051239 726 0.640
Human Mouse Fly
embryo development ending in birth or egg hatching GO:0009792 2992 0.621
Worm
programmed cell death GO:0012501 500 0.583
positive regulation of cellular metabolic process GO:0031325 178 0.570
organ development GO:0048513 1102 0.566
Mouse Worm Fly
embryo development GO:0009790 3052 0.566
Worm
regulation of primary metabolic process GO:0080090 292 0.556
negative regulation of cellular process GO:0048523 239 0.547
Yeast Mouse Rat
cell development GO:0048468 696 0.541
Yeast Mouse Worm
response to organic substance GO:0010033 131 0.523
Human Mouse Rat Fly
cellular nitrogen compound biosynthetic process GO:0044271 192 0.519
organic cyclic compound biosynthetic process GO:1901362 195 0.519
mitotic cell cycle process GO:1903047 194 0.515
positive regulation of cellular process GO:0048522 332 0.515
regulation of macromolecule metabolic process GO:0060255 421 0.509
regulation of nucleic acid templated transcription GO:1903506 165 0.507
single organism reproductive process GO:0044702 1196 0.506
Yeast Worm
aging GO:0007568 812 0.504
Human Worm Fly
single organism signaling GO:0044700 401 0.496
organic substance catabolic process GO:1901575 294 0.496
growth GO:0040007 562 0.494
Mouse Fly
negative regulation of biological process GO:0048519 567 0.490
Yeast Mouse Rat Fly
heterocycle biosynthetic process GO:0018130 187 0.482
gene expression GO:0010467 412 0.479
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.478
cell death GO:0008219 547 0.470
post embryonic development GO:0009791 2152 0.467
Worm Fly
rna metabolic process GO:0016070 228 0.465
protein metabolic process GO:0019538 422 0.460
female gamete generation GO:0007292 254 0.451
Worm
catabolic process GO:0009056 318 0.444
regulation of rna metabolic process GO:0051252 173 0.439
regulation of metabolic process GO:0019222 478 0.436
regulation of nitrogen compound metabolic process GO:0051171 222 0.422
gamete generation GO:0007276 461 0.422
Worm
cellular macromolecule biosynthetic process GO:0034645 247 0.417
apoptotic process GO:0006915 478 0.416
Worm
organelle fission GO:0048285 363 0.396
Worm
transcription dna templated GO:0006351 168 0.385
determination of adult lifespan GO:0008340 812 0.379
Worm Fly
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.378
Worm
developmental growth GO:0048589 412 0.369
Mouse Fly
gonad development GO:0008406 840 0.352
Worm
macromolecule modification GO:0043412 218 0.346
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.344
meiotic nuclear division GO:0007126 300 0.326
Worm
germ cell development GO:0007281 351 0.322
Worm
regulation of cellular component organization GO:0051128 248 0.317
Mouse Worm Fly
regulation of gene expression GO:0010468 366 0.312
regulation of developmental process GO:0050793 684 0.309
Yeast Mouse Fly
death GO:0016265 547 0.305
multi organism reproductive behavior GO:0044705 387 0.302
regulation of cellular biosynthetic process GO:0031326 189 0.296
nucleobase containing compound biosynthetic process GO:0034654 184 0.292
cellular localization GO:0051641 360 0.291
positive regulation of multicellular organismal process GO:0051240 417 0.289
Human Mouse Fly
protein complex subunit organization GO:0071822 280 0.289
Worm
regulation of biosynthetic process GO:0009889 189 0.287
neuron differentiation GO:0030182 217 0.287
regulation of signal transduction GO:0009966 135 0.285
Mouse Fly
organic substance biosynthetic process GO:1901576 323 0.282
response to abiotic stimulus GO:0009628 152 0.281
axonogenesis GO:0007409 102 0.278
behavior GO:0007610 527 0.278
protein modification process GO:0036211 207 0.257
multicellular organismal aging GO:0010259 812 0.248
Worm Fly
cell division GO:0051301 262 0.248
cell morphogenesis GO:0000902 163 0.242
Mouse
positive regulation of developmental growth GO:0048639 354 0.239
Fly
regulation of growth GO:0040008 409 0.239
Fly
development of primary sexual characteristics GO:0045137 840 0.236
Worm
multi multicellular organism process GO:0044706 390 0.229
positive regulation of rna metabolic process GO:0051254 103 0.229
positive regulation of rna biosynthetic process GO:1902680 102 0.226
oviposition GO:0018991 364 0.221
innate immune response GO:0045087 190 0.220
regulation of multicellular organism growth GO:0040014 373 0.218
Fly
meiotic cell cycle GO:0051321 335 0.217
Yeast Worm
regulation of cell cycle process GO:0010564 145 0.216
Yeast
biosynthetic process GO:0009058 323 0.213
aromatic compound biosynthetic process GO:0019438 192 0.211
positive regulation of metabolic process GO:0009893 187 0.210
cellular biosynthetic process GO:0044249 315 0.210
regulation of cell communication GO:0010646 176 0.210
Mouse Fly
reproductive behavior GO:0019098 387 0.205
transcription from rna polymerase ii promoter GO:0006366 149 0.205
positive regulation of gene expression GO:0010628 112 0.204
regulation of rna biosynthetic process GO:2001141 165 0.202
chromosome segregation GO:0007059 180 0.200
response to wounding GO:0009611 4 0.199
Mouse
multicellular organismal reproductive behavior GO:0033057 384 0.197
hermaphrodite genitalia development GO:0040035 734 0.195
Worm
system process GO:0003008 136 0.191
cellular protein modification process GO:0006464 207 0.189
nucleic acid metabolic process GO:0090304 299 0.186
endocytosis GO:0006897 819 0.185
regulation of cytoplasmic transport GO:1903649 3 0.182
Mouse
neuron projection morphogenesis GO:0048812 114 0.181
positive regulation of nucleic acid templated transcription GO:1903508 102 0.179
vesicle mediated transport GO:0016192 852 0.179
regulation of developmental growth GO:0048638 389 0.176
Fly
signal transduction GO:0007165 317 0.174
reproductive system development GO:0061458 850 0.174
Worm
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.172
regulation of biological quality GO:0065008 741 0.172
Mouse Worm Fly
neuron projection development GO:0031175 187 0.171
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.167
nucleobase containing compound metabolic process GO:0006139 406 0.167
positive regulation of transcription dna templated GO:0045893 102 0.164
regulation of multicellular organismal development GO:2000026 317 0.164
Mouse Fly
cell part morphogenesis GO:0032990 152 0.161
oogenesis GO:0048477 229 0.161
Worm
single organism localization GO:1902578 518 0.160
Mouse Worm
cellular response to organic substance GO:0071310 119 0.152
Human Mouse Fly
cellular protein metabolic process GO:0044267 279 0.151
body morphogenesis GO:0010171 620 0.151
multicellular organism growth GO:0035264 385 0.150
Fly
nucleic acid templated transcription GO:0097659 169 0.148
establishment of localization in cell GO:0051649 318 0.147
Mouse Worm
nervous system development GO:0007399 253 0.146
positive regulation of cellular biosynthetic process GO:0031328 109 0.146
receptor mediated endocytosis GO:0006898 715 0.144
multi organism behavior GO:0051705 389 0.143
single organism cellular localization GO:1902580 72 0.142
Mouse Worm
generation of neurons GO:0048699 235 0.142
regulation of cell cycle GO:0051726 194 0.140
Yeast Rat
cellular response to chemical stimulus GO:0070887 129 0.140
Human Mouse Fly
protein localization GO:0008104 205 0.139
response to external stimulus GO:0009605 289 0.138
neuron projection guidance GO:0097485 82 0.138
immune response GO:0006955 192 0.138
positive regulation of macromolecule metabolic process GO:0010604 149 0.135
positive regulation of multicellular organism growth GO:0040018 352 0.134
Fly
muscle structure development GO:0061061 191 0.132
Human Mouse Worm
response to biotic stimulus GO:0009607 101 0.132
regulation of phosphorus metabolic process GO:0051174 81 0.129
Fly
cellular catabolic process GO:0044248 199 0.128
response to endogenous stimulus GO:0009719 33 0.126
Mouse Fly
positive regulation of developmental process GO:0051094 408 0.124
Mouse Fly
cellular component morphogenesis GO:0032989 318 0.122
Yeast Mouse Worm
establishment of localization GO:0051234 1171 0.121
Mouse Worm
response to chemical GO:0042221 356 0.121
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.120
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.120
single organism behavior GO:0044708 83 0.119
positive regulation of growth GO:0045927 369 0.116
Fly
cell growth GO:0016049 44 0.114
cell surface receptor signaling pathway GO:0007166 149 0.113
Human Mouse Fly
cellular component movement GO:0006928 388 0.113
Worm
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.112
regulation of macromolecule biosynthetic process GO:0010556 189 0.111
muscle tissue development GO:0060537 1 0.109
Mouse
regulation of molecular function GO:0065009 89 0.107
cellular response to abiotic stimulus GO:0071214 4 0.106
Human Yeast
neuron development GO:0048666 199 0.105
axon development GO:0061564 163 0.103
regulation of cell differentiation GO:0045595 81 0.101
Yeast Mouse
regulation of phosphate metabolic process GO:0019220 81 0.100
Fly
neurogenesis GO:0022008 236 0.100
macromolecular complex assembly GO:0065003 193 0.098
Worm
cell type specific apoptotic process GO:0097285 4 0.098
actin filament based process GO:0030029 191 0.098
Worm
small molecule metabolic process GO:0044281 186 0.098
Mouse
organonitrogen compound metabolic process GO:1901564 151 0.098
cellular protein localization GO:0034613 75 0.098
mitotic nuclear division GO:0007067 89 0.097
positive regulation of intracellular transport GO:0032388 2 0.095
Mouse
rna biosynthetic process GO:0032774 169 0.094
protein complex biogenesis GO:0070271 186 0.094
Worm
single organism transport GO:0044765 447 0.094
Mouse Worm
positive regulation of signal transduction GO:0009967 40 0.094
tissue development GO:0009888 112 0.091
Mouse
regulation of cellular protein metabolic process GO:0032268 75 0.090
Fly
macromolecule localization GO:0033036 771 0.090
response to external biotic stimulus GO:0043207 101 0.090
sex differentiation GO:0007548 909 0.088
Worm
spindle organization GO:0007051 92 0.087
head development GO:0060322 1 0.087
positive regulation of cell communication GO:0010647 69 0.087
response to oxygen containing compound GO:1901700 44 0.087
negative regulation of developmental process GO:0051093 227 0.086
Yeast
phosphorus metabolic process GO:0006793 232 0.086
striated muscle cell development GO:0055002 157 0.085
Mouse Worm
protein phosphorylation GO:0006468 85 0.085
locomotion GO:0040011 1634 0.081
regulation of bmp signaling pathway GO:0030510 3 0.079
Fly
macromolecule biosynthetic process GO:0009059 250 0.079
macromolecular complex subunit organization GO:0043933 320 0.079
Worm
microtubule based process GO:0007017 182 0.078
regulation of signaling GO:0023051 172 0.078
Mouse Fly
regulation of protein metabolic process GO:0051246 81 0.075
Fly
phosphorylation GO:0016310 116 0.075
reproductive structure development GO:0048608 850 0.074
Worm
cell motility GO:0048870 313 0.074
purine ribonucleotide metabolic process GO:0009150 95 0.073
organelle localization GO:0051640 127 0.073
Worm
muscle cell development GO:0055001 158 0.073
Mouse Worm
cellular component biogenesis GO:0044085 297 0.071
Yeast Worm
secretion GO:0046903 147 0.071
membrane organization GO:0061024 135 0.071
negative regulation of cell cycle GO:0045786 53 0.069
Rat
organelle assembly GO:0070925 214 0.069
Worm
regulation of cell division GO:0051302 142 0.068
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.068
Human
chemotaxis GO:0006935 120 0.067
cytoskeleton organization GO:0007010 339 0.067
Worm
defense response GO:0006952 296 0.067
cellular component assembly GO:0022607 293 0.067
Yeast Worm
cell proliferation GO:0008283 116 0.065
lipid storage GO:0019915 565 0.065
protein complex assembly GO:0006461 186 0.065
Worm
cell projection organization GO:0030030 231 0.065
regulation of organelle organization GO:0033043 164 0.065
lipid localization GO:0010876 573 0.065
defense response to gram negative bacterium GO:0050829 64 0.063
maintenance of location GO:0051235 580 0.063
regulation of nuclear division GO:0051783 115 0.063
mitotic spindle organization GO:0007052 81 0.062
anatomical structure homeostasis GO:0060249 11 0.061
establishment of organelle localization GO:0051656 123 0.061
Worm
response to starvation GO:0042594 26 0.059
Fly
jnk cascade GO:0007254 8 0.058
Worm
muscle cell differentiation GO:0042692 171 0.058
Human Mouse Worm
response to other organism GO:0051707 101 0.058
translation GO:0006412 37 0.057
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.057
signal transduction by phosphorylation GO:0023014 31 0.057
positive regulation of molecular function GO:0044093 61 0.057
response to nutrient levels GO:0031667 35 0.056
Fly
response to heat GO:0009408 50 0.055
Yeast Worm Fly
negative regulation of metabolic process GO:0009892 240 0.055
regulation of neuron differentiation GO:0045664 40 0.055
response to extracellular stimulus GO:0009991 38 0.055
Fly
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.054
cell cell signaling GO:0007267 118 0.054
Worm Fly
defense response to other organism GO:0098542 100 0.053
oocyte development GO:0048599 44 0.053
Worm
anatomical structure formation involved in morphogenesis GO:0048646 250 0.053
Yeast Mouse Worm
intracellular transport GO:0046907 77 0.053
Mouse
striated muscle cell differentiation GO:0051146 158 0.052
Mouse Worm
defense response to bacterium GO:0042742 86 0.052
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.052
purine nucleoside triphosphate metabolic process GO:0009144 87 0.051
ribonucleoside triphosphate metabolic process GO:0009199 87 0.051
cell migration GO:0016477 306 0.049
cell substrate adhesion GO:0031589 1 0.048
positive regulation of signaling GO:0023056 66 0.048
cellular macromolecular complex assembly GO:0034622 184 0.047
Worm
regulation of multi organism process GO:0043900 69 0.047
Fly
autophagy GO:0006914 29 0.047
myofibril assembly GO:0030239 154 0.046
Worm
phosphate containing compound metabolic process GO:0006796 232 0.046
positive regulation of catalytic activity GO:0043085 59 0.046
stress activated mapk cascade GO:0051403 10 0.044
regulation of localization GO:0032879 194 0.044
mapk cascade GO:0000165 31 0.044
homeostatic process GO:0042592 51 0.044
Mouse
axon guidance GO:0007411 82 0.044
establishment or maintenance of cell polarity GO:0007163 63 0.043
actomyosin structure organization GO:0031032 154 0.043
Worm
regulation of translation GO:0006417 19 0.042
spindle localization GO:0051653 51 0.042
macroautophagy GO:0016236 11 0.042
positive regulation of biosynthetic process GO:0009891 109 0.041
regulation of cellular component size GO:0032535 40 0.041
Fly
macromolecule catabolic process GO:0009057 202 0.041
actin cytoskeleton organization GO:0030036 184 0.041
Worm
cellular response to stress GO:0033554 162 0.041
regulation of apoptotic process GO:0042981 36 0.040
positive regulation of cell cycle GO:0045787 55 0.040
skeletal muscle organ development GO:0060538 3 0.040
Mouse
genitalia development GO:0048806 741 0.039
Worm
cellular response to oxygen containing compound GO:1901701 21 0.038
Human Mouse Fly
regulation of muscle cell differentiation GO:0051147 1 0.038
Mouse
regulation of apoptotic signaling pathway GO:2001233 1 0.038
development of primary male sexual characteristics GO:0046546 4 0.037
molting cycle GO:0042303 281 0.037
Fly
cytokinesis GO:0000910 80 0.037
cellular amine metabolic process GO:0044106 15 0.036
male sex differentiation GO:0046661 86 0.036
cell morphogenesis involved in differentiation GO:0000904 112 0.036
localization of cell GO:0051674 313 0.036
meiotic cell cycle process GO:1903046 170 0.036
Yeast
regulation of post embryonic development GO:0048580 260 0.035
cellular protein complex assembly GO:0043623 178 0.035
Worm
posttranscriptional regulation of gene expression GO:0010608 166 0.035
vesicle localization GO:0051648 24 0.034
Worm
intracellular signal transduction GO:0035556 96 0.034
cell projection morphogenesis GO:0048858 148 0.034
regulation of mitotic cell cycle GO:0007346 76 0.034
positive regulation of transport GO:0051050 32 0.034
Mouse
regulation of intracellular signal transduction GO:1902531 77 0.033
embryonic morphogenesis GO:0048598 152 0.033
positive regulation of response to stimulus GO:0048584 55 0.033
establishment of mitotic spindle localization GO:0040001 41 0.033
aromatic compound catabolic process GO:0019439 116 0.033
response to endoplasmic reticulum stress GO:0034976 71 0.033
Worm
positive regulation of neuron differentiation GO:0045666 4 0.032
nucleoside catabolic process GO:0009164 78 0.032
regulation of cell proliferation GO:0042127 105 0.031
positive regulation of neurogenesis GO:0050769 4 0.031
secretion by cell GO:0032940 138 0.031
organic cyclic compound catabolic process GO:1901361 119 0.031
protein catabolic process GO:0030163 162 0.031
regeneration GO:0031099 4 0.031
Mouse
regulation of cell death GO:0010941 65 0.030
single organism catabolic process GO:0044712 129 0.029
regulation of neurotransmitter levels GO:0001505 36 0.029
peptidyl serine modification GO:0018209 20 0.029
single organism intracellular transport GO:1902582 70 0.029
Mouse
post embryonic organ development GO:0048569 336 0.029
Fly
striated muscle myosin thick filament assembly GO:0071688 138 0.028
Worm
regulation of immune response GO:0050776 10 0.028
Fly
carbohydrate derivative metabolic process GO:1901135 141 0.028
protein localization to organelle GO:0033365 37 0.028
response to fungus GO:0009620 20 0.027
Fly
positive regulation of transcription from rna polymerase ii promoter involved in defense response to gram negative bacterium GO:1902097 4 0.027
positive regulation of protein modification process GO:0031401 29 0.027
Fly
single organism organelle organization GO:1902589 501 0.027
Worm
oxoacid metabolic process GO:0043436 47 0.027
Mouse
single organism membrane organization GO:0044802 35 0.027
nucleoside phosphate metabolic process GO:0006753 108 0.026
purine ribonucleoside metabolic process GO:0046128 92 0.026
developmental maturation GO:0021700 26 0.026
Worm Fly
myosin filament organization GO:0031033 138 0.026
Worm
regulation of catalytic activity GO:0050790 78 0.026
male gamete generation GO:0048232 41 0.025
regulation of cell size GO:0008361 30 0.025
Fly
negative regulation of signal transduction GO:0009968 60 0.025
Mouse
sensory organ morphogenesis GO:0090596 2 0.024
negative regulation of gene expression GO:0010629 217 0.024
nucleoside triphosphate metabolic process GO:0009141 87 0.024
neurological system process GO:0050877 53 0.024
organophosphate metabolic process GO:0019637 125 0.024
negative regulation of post embryonic development GO:0048581 208 0.024
locomotory behavior GO:0007626 40 0.024
muscle fiber development GO:0048747 2 0.024
Mouse
response to transition metal nanoparticle GO:1990267 18 0.023
Worm
regulation of protein localization GO:0032880 50 0.023
defense response to fungus GO:0050832 19 0.023
Fly
apoptotic cell clearance GO:0043277 111 0.023
engulfment of apoptotic cell GO:0043652 94 0.023
cellular response to inorganic substance GO:0071241 3 0.023
Fly
positive regulation of cell death GO:0010942 38 0.023
cellular response to nutrient levels GO:0031669 13 0.023
stress activated protein kinase signaling cascade GO:0031098 10 0.023
cell cycle phase transition GO:0044770 19 0.023
establishment of spindle localization GO:0051293 51 0.023
ribonucleoside metabolic process GO:0009119 98 0.022
protein modification by small protein conjugation or removal GO:0070647 40 0.022
cellular lipid metabolic process GO:0044255 40 0.022
Mouse
response to nitrogen compound GO:1901698 25 0.022
Mouse
establishment of mitotic spindle orientation GO:0000132 28 0.022
negative regulation of cell communication GO:0010648 61 0.022
Mouse
regulation of programmed cell death GO:0043067 50 0.021
vulval development GO:0040025 333 0.021
tissue morphogenesis GO:0048729 65 0.021
carboxylic acid metabolic process GO:0019752 34 0.021
Mouse
chromosome organization GO:0051276 104 0.021
amine metabolic process GO:0009308 15 0.020
cellular amino acid metabolic process GO:0006520 15 0.020
regulation of protein import into nucleus GO:0042306 3 0.020
Mouse
regulation of catabolic process GO:0009894 57 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
peptidyl amino acid modification GO:0018193 58 0.020
heterocycle catabolic process GO:0046700 119 0.019
dauer larval development GO:0040024 92 0.019
spermatogenesis GO:0007283 41 0.019
organophosphate catabolic process GO:0046434 81 0.019
positive regulation of immune response GO:0050778 7 0.019
positive regulation of hydrolase activity GO:0051345 38 0.019
response to temperature stimulus GO:0009266 66 0.019
Yeast Worm Fly
intraspecies interaction between organisms GO:0051703 3 0.019
nitrogen compound transport GO:0071705 49 0.018
myosin filament assembly GO:0031034 138 0.018
Worm
female meiotic division GO:0007143 17 0.018
Worm
establishment of vesicle localization GO:0051650 23 0.018
Worm
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 16 0.018
Mouse Fly
phagocytosis engulfment GO:0006911 98 0.018
organelle fusion GO:0048284 8 0.018
small gtpase mediated signal transduction GO:0007264 32 0.018
proteolysis GO:0006508 61 0.018
neuromuscular junction development GO:0007528 2 0.018
pigment metabolic process GO:0042440 2 0.018
inductive cell migration GO:0040039 145 0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 12 0.017
Fly
sister chromatid segregation GO:0000819 46 0.017
bmp signaling pathway GO:0030509 3 0.017
Fly
gtp catabolic process GO:0006184 46 0.017
cellular homeostasis GO:0019725 22 0.017
response to metal ion GO:0010038 33 0.017
Worm Fly
regulation of cell development GO:0060284 49 0.017
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.017
regulation of neuron projection development GO:0010975 31 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
purine nucleotide metabolic process GO:0006163 95 0.017
ribose phosphate metabolic process GO:0019693 99 0.017
purine nucleoside catabolic process GO:0006152 75 0.017
cellular nitrogen compound catabolic process GO:0044270 119 0.017
regulation of response to stress GO:0080134 28 0.016
Fly
positive regulation of chromosome organization GO:2001252 2 0.016
ribonucleotide metabolic process GO:0009259 99 0.016
oocyte differentiation GO:0009994 45 0.016
Worm
regulation of neurotransmitter secretion GO:0046928 16 0.016
positive regulation of locomotion GO:0040017 42 0.016
microtubule polymerization or depolymerization GO:0031109 22 0.016
response to oxidative stress GO:0006979 42 0.016
positive regulation of protein transport GO:0051222 4 0.016
Mouse
positive regulation of programmed cell death GO:0043068 27 0.016
neurotransmitter transport GO:0006836 32 0.016
neuron recognition GO:0008038 83 0.016
pigmentation GO:0043473 2 0.016
Fly
regulation of cytoskeleton organization GO:0051493 41 0.016
organic acid metabolic process GO:0006082 47 0.016
Mouse
regulation of protein targeting GO:1903533 3 0.015
Mouse
cellular component assembly involved in morphogenesis GO:0010927 183 0.015
Yeast Worm
oxidation reduction process GO:0055114 59 0.015
Mouse
cellular response to topologically incorrect protein GO:0035967 76 0.015
purine containing compound metabolic process GO:0072521 95 0.015
apoptotic mitochondrial changes GO:0008637 2 0.015
purine nucleoside metabolic process GO:0042278 92 0.015
rna localization GO:0006403 3 0.015
cell matrix adhesion GO:0007160 1 0.015
cellular ketone metabolic process GO:0042180 14 0.015
immune response regulating signaling pathway GO:0002764 1 0.015
glycosyl compound metabolic process GO:1901657 100 0.015
regulation of anatomical structure morphogenesis GO:0022603 51 0.015
Yeast Mouse
nucleobase containing compound catabolic process GO:0034655 114 0.015
protein oligomerization GO:0051259 4 0.015
establishment of protein localization to membrane GO:0090150 3 0.015
nucleoside triphosphate catabolic process GO:0009143 72 0.014
neuron apoptotic process GO:0051402 4 0.014
regulation of nematode larval development GO:0061062 260 0.014
nucleoside metabolic process GO:0009116 99 0.014
lipid metabolic process GO:0006629 77 0.014
Mouse
positive regulation of cellular component organization GO:0051130 34 0.014
Mouse
dendrite development GO:0016358 42 0.014
mitotic cell cycle phase transition GO:0044772 13 0.014
negative regulation of multicellular organismal process GO:0051241 236 0.014
regulation of response to stimulus GO:0048583 243 0.014
Mouse Fly
taxis GO:0042330 128 0.014
glycoprotein metabolic process GO:0009100 29 0.014
carbohydrate derivative biosynthetic process GO:1901137 46 0.014
rna interference GO:0016246 137 0.014
cellular macromolecule localization GO:0070727 75 0.014
regulation of gtp catabolic process GO:0033124 32 0.013
nucleus organization GO:0006997 38 0.013
regulation of nucleocytoplasmic transport GO:0046822 3 0.013
Mouse
golgi vesicle transport GO:0048193 3 0.013
filopodium assembly GO:0046847 2 0.013
regulation of cellular component movement GO:0051270 62 0.013
mitochondrion organization GO:0007005 20 0.013
positive regulation of apoptotic process GO:0043065 17 0.013
cellular response to nitrogen compound GO:1901699 24 0.013
establishment of spindle orientation GO:0051294 34 0.013
protein localization to nucleus GO:0034504 11 0.013
regulation of vulval development GO:0040028 248 0.013
nematode male tail tip morphogenesis GO:0045138 77 0.013
secondary metabolic process GO:0019748 3 0.013
enzyme linked receptor protein signaling pathway GO:0007167 50 0.013
Human Mouse Fly
defense response to gram positive bacterium GO:0050830 31 0.013
cell adhesion GO:0007155 21 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
nucleoside phosphate catabolic process GO:1901292 77 0.012
response to osmotic stress GO:0006970 29 0.012
regulation of meiotic cell cycle GO:0051445 136 0.012
positive regulation of phosphorus metabolic process GO:0010562 56 0.012
Fly
single organism carbohydrate metabolic process GO:0044723 29 0.012
Mouse
establishment of protein localization GO:0045184 50 0.012
Mouse
g1 s transition of mitotic cell cycle GO:0000082 2 0.012
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.012
monosaccharide metabolic process GO:0005996 2 0.012
Mouse
negative regulation of response to stimulus GO:0048585 73 0.012
Mouse Fly
ras protein signal transduction GO:0007265 31 0.012
glycosyl compound catabolic process GO:1901658 79 0.012
axonal fasciculation GO:0007413 79 0.012
meiotic chromosome segregation GO:0045132 139 0.012
regulation of phosphorylation GO:0042325 45 0.012
Fly
response to bacterium GO:0009617 86 0.012
neurotransmitter secretion GO:0007269 26 0.012
epithelium development GO:0060429 68 0.012
nucleobase containing small molecule metabolic process GO:0055086 115 0.012
positive regulation of cell migration GO:0030335 3 0.012
cytoskeleton dependent cytokinesis GO:0061640 35 0.012

pmk-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.023
disease of cellular proliferation DOID:14566 0 0.023
organ system cancer DOID:0050686 0 0.023