Caenorhabditis elegans

38 known processes

unc-27 (CELE_ZK721.2)

Protein UNC-27

unc-27 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle organ development GO:0007517 26 0.842
Mouse
organ development GO:0048513 1102 0.777
Mouse Worm
embryo development GO:0009790 3052 0.720
Worm
locomotion GO:0040011 1634 0.668
system process GO:0003008 136 0.467
protein catabolic process GO:0030163 162 0.466
transport GO:0006810 1093 0.453
developmental process involved in reproduction GO:0003006 1165 0.445
Worm
embryo development ending in birth or egg hatching GO:0009792 2992 0.436
Worm
hermaphrodite genitalia development GO:0040035 734 0.406
Worm
post embryonic development GO:0009791 2152 0.401
Worm
cell migration GO:0016477 306 0.400
cellular component biogenesis GO:0044085 297 0.396
multicellular organismal reproductive behavior GO:0033057 384 0.391
Worm
genitalia development GO:0048806 741 0.337
Worm
reproductive structure development GO:0048608 850 0.334
Worm
skeletal muscle organ development GO:0060538 3 0.333
sarcomere organization GO:0045214 10 0.326
sex differentiation GO:0007548 909 0.320
Worm
organelle organization GO:0006996 783 0.319
gonad development GO:0008406 840 0.316
Worm
generation of neurons GO:0048699 235 0.314
Worm
establishment of localization GO:0051234 1171 0.301
vesicle mediated transport GO:0016192 852 0.289
cellular component assembly GO:0022607 293 0.279
reproductive system development GO:0061458 850 0.271
Worm
receptor mediated endocytosis GO:0006898 715 0.269
regulation of multicellular organismal process GO:0051239 726 0.260
Mouse
single organism organelle organization GO:1902589 501 0.254
cell motility GO:0048870 313 0.254
multicellular organism reproduction GO:0032504 819 0.245
Worm
single organism reproductive process GO:0044702 1196 0.244
Worm
development of primary sexual characteristics GO:0045137 840 0.240
Worm
positive regulation of multicellular organismal process GO:0051240 417 0.239
organelle assembly GO:0070925 214 0.239
multicellular organismal aging GO:0010259 812 0.232
behavior GO:0007610 527 0.227
Worm
muscle organ morphogenesis GO:0048644 4 0.225
Mouse
neurogenesis GO:0022008 236 0.220
Worm
cell development GO:0048468 696 0.217
muscle tissue development GO:0060537 1 0.212
Mouse
multicellular organismal reproductive process GO:0048609 815 0.209
Worm
determination of adult lifespan GO:0008340 812 0.208
muscle system process GO:0003012 43 0.200
Mouse Worm
macromolecule catabolic process GO:0009057 202 0.200
cellular component assembly involved in morphogenesis GO:0010927 183 0.192
nervous system development GO:0007399 253 0.177
Worm
striated muscle cell development GO:0055002 157 0.177
muscle structure development GO:0061061 191 0.170
actin cytoskeleton organization GO:0030036 184 0.169
muscle cell differentiation GO:0042692 171 0.154
actomyosin structure organization GO:0031032 154 0.149
cellular homeostasis GO:0019725 22 0.149
Mouse
organic substance catabolic process GO:1901575 294 0.148
multi organism behavior GO:0051705 389 0.143
Worm
myofibril assembly GO:0030239 154 0.141
response to external stimulus GO:0009605 289 0.138
pharyngeal pumping GO:0043050 58 0.132
Worm
catabolic process GO:0009056 318 0.131
neuron projection development GO:0031175 187 0.130
Worm
regulation of muscle system process GO:0090257 20 0.128
Mouse
oviposition GO:0018991 364 0.128
Worm
macromolecule localization GO:0033036 771 0.122
anatomical structure formation involved in morphogenesis GO:0048646 250 0.119
multi organism reproductive process GO:0044703 867 0.118
Worm
muscle cell development GO:0055001 158 0.117
protein complex subunit organization GO:0071822 280 0.115
cell part morphogenesis GO:0032990 152 0.115
Worm
protein metabolic process GO:0019538 422 0.113
multi organism reproductive behavior GO:0044705 387 0.111
Worm
macromolecular complex subunit organization GO:0043933 320 0.099
endocytosis GO:0006897 819 0.098
cellular component morphogenesis GO:0032989 318 0.096
actin filament based process GO:0030029 191 0.094
lipid localization GO:0010876 573 0.089
maintenance of location GO:0051235 580 0.087
cell projection morphogenesis GO:0048858 148 0.087
Worm
aging GO:0007568 812 0.086
regulation of developmental process GO:0050793 684 0.086
cytoskeleton organization GO:0007010 339 0.086
cell projection organization GO:0030030 231 0.084
Worm
striated muscle cell differentiation GO:0051146 158 0.082
lipid storage GO:0019915 565 0.081
protein complex biogenesis GO:0070271 186 0.080
striated muscle contraction GO:0006941 17 0.079
Mouse
regulation of system process GO:0044057 27 0.077
Mouse
regulation of biological quality GO:0065008 741 0.077
Mouse
organelle fission GO:0048285 363 0.076
axonogenesis GO:0007409 102 0.076
Worm
ion homeostasis GO:0050801 21 0.074
Mouse
neuron development GO:0048666 199 0.070
Worm
defense response GO:0006952 296 0.066
eating behavior GO:0042755 59 0.064
Worm
reproductive behavior GO:0019098 387 0.063
Worm
cellular protein complex assembly GO:0043623 178 0.063
cell division GO:0051301 262 0.062
asymmetric protein localization GO:0008105 35 0.061
axon development GO:0061564 163 0.059
Worm
directional locomotion GO:0033058 14 0.059
Worm
meiotic nuclear division GO:0007126 300 0.059
protein complex assembly GO:0006461 186 0.058
single organism localization GO:1902578 518 0.057
cell cycle process GO:0022402 482 0.056
cellular component movement GO:0006928 388 0.056
growth GO:0040007 562 0.053
cell cycle GO:0007049 526 0.052
multi multicellular organism process GO:0044706 390 0.052
Worm
cell morphogenesis GO:0000902 163 0.052
Worm
regulation of muscle contraction GO:0006937 20 0.052
Mouse
macromolecular complex assembly GO:0065003 193 0.051
negative regulation of nematode larval development GO:0061064 208 0.049
multicellular organism growth GO:0035264 385 0.047
feeding behavior GO:0007631 70 0.046
Worm
cell morphogenesis involved in differentiation GO:0000904 112 0.045
Worm
immune response GO:0006955 192 0.045
muscle contraction GO:0006936 43 0.045
Mouse Worm
negative regulation of developmental process GO:0051093 227 0.045
protein localization GO:0008104 205 0.044
response to chemical GO:0042221 356 0.044
positive regulation of multicellular organism growth GO:0040018 352 0.044
inductive cell migration GO:0040039 145 0.044
cellular nitrogen compound biosynthetic process GO:0044271 192 0.042
actin filament organization GO:0007015 21 0.042
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.042
regulation of growth GO:0040008 409 0.041
localization of cell GO:0051674 313 0.041
chemical homeostasis GO:0048878 29 0.040
Mouse
single organism transport GO:0044765 447 0.040
meiotic cell cycle GO:0051321 335 0.039
ovulation GO:0030728 33 0.039
molting cycle GO:0042303 281 0.039
neuron recognition GO:0008038 83 0.038
positive regulation of developmental growth GO:0048639 354 0.038
vulval development GO:0040025 333 0.038
response to wounding GO:0009611 4 0.038
regulation of multicellular organism growth GO:0040014 373 0.038
negative regulation of vulval development GO:0040027 206 0.038
cellular catabolic process GO:0044248 199 0.037
body morphogenesis GO:0010171 620 0.037
Worm
digestive system development GO:0055123 122 0.036
regulation of nematode larval development GO:0061062 260 0.036
innate immune response GO:0045087 190 0.036
defense response to other organism GO:0098542 100 0.036
cellular macromolecular complex assembly GO:0034622 184 0.035
gamete generation GO:0007276 461 0.034
biosynthetic process GO:0009058 323 0.034
positive regulation of developmental process GO:0051094 408 0.034
establishment or maintenance of cell polarity GO:0007163 63 0.034
cell fate commitment GO:0045165 139 0.033
neuron projection morphogenesis GO:0048812 114 0.032
Worm
regulation of multicellular organismal development GO:2000026 317 0.030
phagocytosis GO:0006909 115 0.030
skeletal muscle thin filament assembly GO:0030240 3 0.030
negative regulation of gene expression GO:0010629 217 0.030
excretion GO:0007588 49 0.029
neuron differentiation GO:0030182 217 0.029
Worm
positive regulation of growth GO:0045927 369 0.029
sexual reproduction GO:0019953 546 0.029
mitotic cell cycle process GO:1903047 194 0.028
post embryonic organ development GO:0048569 336 0.028
regulation of developmental growth GO:0048638 389 0.028
negative regulation of dna dependent dna replication GO:2000104 1 0.027
regulation of post embryonic development GO:0048580 260 0.027
regulation of vulval development GO:0040028 248 0.026
cell recognition GO:0008037 85 0.026
embryonic morphogenesis GO:0048598 152 0.026
negative regulation of post embryonic development GO:0048581 208 0.026
regulation of macromolecule metabolic process GO:0060255 421 0.025
taxis GO:0042330 128 0.025
regulation of localization GO:0032879 194 0.025
developmental growth GO:0048589 412 0.024
tissue development GO:0009888 112 0.024
Mouse
secretion by cell GO:0032940 138 0.024
membrane invagination GO:0010324 98 0.024
meiotic cell cycle process GO:1903046 170 0.024
cuticle development GO:0042335 100 0.023
nucleobase containing compound metabolic process GO:0006139 406 0.023
nucleic acid metabolic process GO:0090304 299 0.022
chemotaxis GO:0006935 120 0.022
tissue morphogenesis GO:0048729 65 0.021
Mouse
organic substance biosynthetic process GO:1901576 323 0.021
cytokinesis GO:0000910 80 0.021
gene expression GO:0010467 412 0.021
striated muscle myosin thick filament assembly GO:0071688 138 0.021
cell death GO:0008219 547 0.021
negative regulation of biological process GO:0048519 567 0.021
regulation of cell cycle GO:0051726 194 0.021
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.021
Worm
organonitrogen compound metabolic process GO:1901564 151 0.020
mitotic nuclear division GO:0007067 89 0.020
cellular response to unfolded protein GO:0034620 71 0.020
regulation of gene expression GO:0010468 366 0.020
positive regulation of cysteine type endopeptidase activity GO:2001056 3 0.019
cellular metal ion homeostasis GO:0006875 7 0.019
Mouse
regulation of response to stimulus GO:0048583 243 0.018
Mouse
regulation of cellular component organization GO:0051128 248 0.018
secretion GO:0046903 147 0.018
small molecule metabolic process GO:0044281 186 0.018
response to external biotic stimulus GO:0043207 101 0.017
regulation of feeding behavior GO:0060259 38 0.017
regulation of apoptotic signaling pathway GO:2001233 1 0.017
negative regulation of metabolic process GO:0009892 240 0.017
cellular ion homeostasis GO:0006873 11 0.017
Mouse
regulation of metabolic process GO:0019222 478 0.016
axonal fasciculation GO:0007413 79 0.016
myosin filament assembly GO:0031034 138 0.016
neuron projection guidance GO:0097485 82 0.016
response to biotic stimulus GO:0009607 101 0.016
single organism behavior GO:0044708 83 0.015
negative regulation of cellular process GO:0048523 239 0.015
organic cyclic compound catabolic process GO:1901361 119 0.015
engulfment of apoptotic cell GO:0043652 94 0.015
regulation of cellular component size GO:0032535 40 0.015
apoptotic cell clearance GO:0043277 111 0.015
regulation of behavior GO:0050795 97 0.015
embryonic body morphogenesis GO:0010172 49 0.015
regulation of locomotion GO:0040012 161 0.015
posttranscriptional regulation of gene expression GO:0010608 166 0.015
calcium ion homeostasis GO:0055074 6 0.015
Mouse
myosin filament organization GO:0031033 138 0.014
muscle fiber development GO:0048747 2 0.014
cellular biosynthetic process GO:0044249 315 0.014
collagen and cuticulin based cuticle development GO:0040002 99 0.014
signaling GO:0023052 401 0.014
actin filament bundle assembly GO:0051017 3 0.013
germ cell development GO:0007281 351 0.013
negative regulation of multicellular organismal process GO:0051241 236 0.013
death GO:0016265 547 0.013
regulation of cellular metabolic process GO:0031323 305 0.013
regulation of intrinsic apoptotic signaling pathway GO:2001242 1 0.013
regulation of cell motility GO:2000145 57 0.013
phagocytosis engulfment GO:0006911 98 0.013
defense response to gram negative bacterium GO:0050829 64 0.013
regulation of cell migration GO:0030334 55 0.012
cellular macromolecule biosynthetic process GO:0034645 247 0.012
heterocycle catabolic process GO:0046700 119 0.012
cellular localization GO:0051641 360 0.011
organ morphogenesis GO:0009887 67 0.011
Mouse
regulation of organelle organization GO:0033043 164 0.011
tube development GO:0035295 126 0.011
regulation of cell communication GO:0010646 176 0.011
single organism signaling GO:0044700 401 0.011
aromatic compound catabolic process GO:0019439 116 0.011
cellular response to stress GO:0033554 162 0.011
programmed cell death GO:0012501 500 0.011
meiotic cytokinesis GO:0033206 15 0.010
somatic muscle development GO:0007525 1 0.010
membrane organization GO:0061024 135 0.010
negative regulation of response to stimulus GO:0048585 73 0.010

unc-27 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
disease of mental health DOID:150 0 0.013
developmental disorder of mental health DOID:0060037 0 0.013
lipodystrophy DOID:811 0 0.013
skin disease DOID:37 0 0.013
integumentary system disease DOID:16 0 0.013
familial partial lipodystrophy DOID:0050440 0 0.013
heart disease DOID:114 0 0.012
cardiovascular system disease DOID:1287 0 0.012