Caenorhabditis elegans

0 known processes

brp-1 (CELE_Y79H2A.1)

Protein BRP-1

brp-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell surface receptor signaling pathway GO:0007166 149 0.650
Worm
multicellular organismal reproductive behavior GO:0033057 384 0.577
embryo development ending in birth or egg hatching GO:0009792 2992 0.573
single organism reproductive process GO:0044702 1196 0.535
small molecule biosynthetic process GO:0044283 38 0.524
sexual reproduction GO:0019953 546 0.501
localization of cell GO:0051674 313 0.486
embryo development GO:0009790 3052 0.480
cell development GO:0048468 696 0.473
gene expression GO:0010467 412 0.451
multicellular organism reproduction GO:0032504 819 0.431
biosynthetic process GO:0009058 323 0.425
regulation of cellular metabolic process GO:0031323 305 0.378
regulation of locomotion GO:0040012 161 0.373
regulation of gene expression GO:0010468 366 0.371
multi organism reproductive behavior GO:0044705 387 0.362
regulation of cellular biosynthetic process GO:0031326 189 0.348
regulation of macromolecule metabolic process GO:0060255 421 0.344
oviposition GO:0018991 364 0.339
cellular biosynthetic process GO:0044249 315 0.339
cell migration GO:0016477 306 0.322
multicellular organismal reproductive process GO:0048609 815 0.315
behavior GO:0007610 527 0.313
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.313
cellular component movement GO:0006928 388 0.310
multi organism reproductive process GO:0044703 867 0.309
developmental process involved in reproduction GO:0003006 1165 0.297
organic substance biosynthetic process GO:1901576 323 0.289
germ cell development GO:0007281 351 0.274
regulation of nucleic acid templated transcription GO:1903506 165 0.273
nucleobase containing compound metabolic process GO:0006139 406 0.271
positive regulation of metabolic process GO:0009893 187 0.257
organ development GO:0048513 1102 0.255
lipid biosynthetic process GO:0008610 28 0.254
regulation of molecular function GO:0065009 89 0.243
anatomical structure formation involved in morphogenesis GO:0048646 250 0.238
regulation of macromolecule biosynthetic process GO:0010556 189 0.225
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.221
signal transduction GO:0007165 317 0.214
Worm
regulation of cell cycle GO:0051726 194 0.212
system process GO:0003008 136 0.212
regulation of cellular protein metabolic process GO:0032268 75 0.212
regulation of biological quality GO:0065008 741 0.211
neurogenesis GO:0022008 236 0.210
single organism signaling GO:0044700 401 0.209
Worm
regulation of metabolic process GO:0019222 478 0.201
reproductive behavior GO:0019098 387 0.199
multi multicellular organism process GO:0044706 390 0.196
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.196
post embryonic development GO:0009791 2152 0.195
positive regulation of cellular process GO:0048522 332 0.189
Worm
rna metabolic process GO:0016070 228 0.183
aromatic compound biosynthetic process GO:0019438 192 0.181
response to external stimulus GO:0009605 289 0.180
regulation of biosynthetic process GO:0009889 189 0.178
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.178
heterocycle biosynthetic process GO:0018130 187 0.177
negative regulation of macromolecule metabolic process GO:0010605 229 0.175
multi organism behavior GO:0051705 389 0.175
growth GO:0040007 562 0.175
transcription from rna polymerase ii promoter GO:0006366 149 0.173
regulation of primary metabolic process GO:0080090 292 0.170
regulation of mitotic cell cycle GO:0007346 76 0.163
tissue development GO:0009888 112 0.163
signaling GO:0023052 401 0.155
Worm
negative regulation of biological process GO:0048519 567 0.154
locomotion GO:0040011 1634 0.154
carboxylic acid biosynthetic process GO:0046394 21 0.153
regulation of cellular component movement GO:0051270 62 0.153
negative regulation of cellular process GO:0048523 239 0.149
regulation of rna metabolic process GO:0051252 173 0.146
transport GO:0006810 1093 0.146
muscle structure development GO:0061061 191 0.144
oogenesis GO:0048477 229 0.141
regulation of cell migration GO:0030334 55 0.141
cellular macromolecule biosynthetic process GO:0034645 247 0.140
regulation of developmental process GO:0050793 684 0.138
Worm
gamete generation GO:0007276 461 0.138
intracellular transport GO:0046907 77 0.136
generation of neurons GO:0048699 235 0.135
muscle contraction GO:0006936 43 0.133
nucleic acid templated transcription GO:0097659 169 0.130
regulation of response to stimulus GO:0048583 243 0.127
Worm
response to chemical GO:0042221 356 0.126
regulation of nitrogen compound metabolic process GO:0051171 222 0.125
nucleic acid metabolic process GO:0090304 299 0.125
cellular component assembly GO:0022607 293 0.124
macromolecular complex subunit organization GO:0043933 320 0.124
reproductive system development GO:0061458 850 0.123
multicellular organism growth GO:0035264 385 0.123
cell cycle GO:0007049 526 0.123
negative regulation of cellular protein metabolic process GO:0032269 27 0.121
muscle tissue development GO:0060537 1 0.116
multicellular organismal aging GO:0010259 812 0.116
developmental growth GO:0048589 412 0.113
negative regulation of gene expression GO:0010629 217 0.113
organic cyclic compound biosynthetic process GO:1901362 195 0.112
positive regulation of cellular biosynthetic process GO:0031328 109 0.109
positive regulation of growth GO:0045927 369 0.108
positive regulation of response to stimulus GO:0048584 55 0.107
Worm
cell motility GO:0048870 313 0.106
response to organic substance GO:0010033 131 0.104
negative regulation of multicellular organismal process GO:0051241 236 0.103
gonad development GO:0008406 840 0.102
regulation of protein metabolic process GO:0051246 81 0.102
monocarboxylic acid biosynthetic process GO:0072330 13 0.101
small molecule metabolic process GO:0044281 186 0.101
muscle cell differentiation GO:0042692 171 0.098
immune response GO:0006955 192 0.095
regulation of multicellular organismal process GO:0051239 726 0.095
regulation of developmental growth GO:0048638 389 0.093
muscle system process GO:0003012 43 0.092
enzyme linked receptor protein signaling pathway GO:0007167 50 0.092
fatty acid biosynthetic process GO:0006633 10 0.089
single organism biosynthetic process GO:0044711 91 0.089
positive regulation of multicellular organismal process GO:0051240 417 0.089
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.085
regulation of growth GO:0040008 409 0.084
striated muscle cell development GO:0055002 157 0.084
macromolecule localization GO:0033036 771 0.084
establishment of localization GO:0051234 1171 0.084
cellular component morphogenesis GO:0032989 318 0.083
sex differentiation GO:0007548 909 0.082
lipid localization GO:0010876 573 0.081
nucleobase containing compound biosynthetic process GO:0034654 184 0.080
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.080
organic acid biosynthetic process GO:0016053 21 0.079
regulation of multicellular organismal development GO:2000026 317 0.079
protein complex assembly GO:0006461 186 0.076
neuron differentiation GO:0030182 217 0.074
reproductive structure development GO:0048608 850 0.073
body morphogenesis GO:0010171 620 0.073
transcription dna templated GO:0006351 168 0.072
regulation of cellular component organization GO:0051128 248 0.072
regulation of multicellular organism growth GO:0040014 373 0.071
maintenance of location GO:0051235 580 0.070
regulation of cell proliferation GO:0042127 105 0.069
cellular response to organic substance GO:0071310 119 0.069
muscle cell development GO:0055001 158 0.068
positive regulation of developmental process GO:0051094 408 0.068
positive regulation of multicellular organism growth GO:0040018 352 0.066
lipid storage GO:0019915 565 0.066
single organism localization GO:1902578 518 0.066
cellular lipid metabolic process GO:0044255 40 0.065
post embryonic organ development GO:0048569 336 0.065
negative regulation of cell cycle GO:0045786 53 0.065
response to acid chemical GO:0001101 4 0.063
negative regulation of cellular biosynthetic process GO:0031327 65 0.062
regulation of cell motility GO:2000145 57 0.062
protein catabolic process GO:0030163 162 0.061
tube development GO:0035295 126 0.060
response to external biotic stimulus GO:0043207 101 0.060
cellular response to chemical stimulus GO:0070887 129 0.059
lipid metabolic process GO:0006629 77 0.059
catabolic process GO:0009056 318 0.056
cellular component biogenesis GO:0044085 297 0.056
rna biosynthetic process GO:0032774 169 0.056
cellular localization GO:0051641 360 0.055
digestive system development GO:0055123 122 0.054
development of primary sexual characteristics GO:0045137 840 0.054
regulation of transcription dna templated GO:0006355 164 0.054
cellular component assembly involved in morphogenesis GO:0010927 183 0.053
macromolecular complex assembly GO:0065003 193 0.053
nervous system development GO:0007399 253 0.052
endocytosis GO:0006897 819 0.052
intracellular signal transduction GO:0035556 96 0.052
receptor mediated endocytosis GO:0006898 715 0.051
negative regulation of metabolic process GO:0009892 240 0.051
macromolecule catabolic process GO:0009057 202 0.050
positive regulation of developmental growth GO:0048639 354 0.050
genitalia development GO:0048806 741 0.050
cellular protein modification process GO:0006464 207 0.049
regulation of rna biosynthetic process GO:2001141 165 0.049
oxoacid metabolic process GO:0043436 47 0.049
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.048
defense response GO:0006952 296 0.048
response to biotic stimulus GO:0009607 101 0.048
female gamete generation GO:0007292 254 0.047
negative regulation of developmental process GO:0051093 227 0.046
vesicle mediated transport GO:0016192 852 0.046
positive regulation of rna biosynthetic process GO:1902680 102 0.046
protein complex biogenesis GO:0070271 186 0.046
single fertilization GO:0007338 61 0.046
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.045
digestive tract development GO:0048565 122 0.045
embryonic morphogenesis GO:0048598 152 0.045
negative regulation of cellular metabolic process GO:0031324 95 0.045
death GO:0016265 547 0.044
regulation of neuron differentiation GO:0045664 40 0.043
regulation of localization GO:0032879 194 0.043
carboxylic acid metabolic process GO:0019752 34 0.043
protein modification process GO:0036211 207 0.043
regulation of transferase activity GO:0051338 31 0.042
positive regulation of cell cycle GO:0045787 55 0.042
negative regulation of protein metabolic process GO:0051248 27 0.042
regulation of catalytic activity GO:0050790 78 0.042
phosphorus metabolic process GO:0006793 232 0.041
cell cycle process GO:0022402 482 0.040
organelle organization GO:0006996 783 0.040
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.039
molting cycle GO:0042303 281 0.038
mitotic cell cycle process GO:1903047 194 0.038
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.038
cell type specific apoptotic process GO:0097285 4 0.038
organ morphogenesis GO:0009887 67 0.038
posttranscriptional regulation of gene expression GO:0010608 166 0.037
membrane organization GO:0061024 135 0.037
organic substance transport GO:0071702 113 0.037
cellular nitrogen compound biosynthetic process GO:0044271 192 0.036
epithelium development GO:0060429 68 0.036
phosphorylation GO:0016310 116 0.036
single organism intracellular transport GO:1902582 70 0.035
organelle assembly GO:0070925 214 0.035
positive regulation of transcription dna templated GO:0045893 102 0.035
organic acid metabolic process GO:0006082 47 0.035
neuron projection development GO:0031175 187 0.033
response to abiotic stimulus GO:0009628 152 0.033
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.033
vulval development GO:0040025 333 0.033
protein metabolic process GO:0019538 422 0.033
regulation of lipid metabolic process GO:0019216 4 0.033
rrna processing GO:0006364 3 0.033
skeletal muscle organ development GO:0060538 3 0.033
regulation of neurogenesis GO:0050767 40 0.032
protein localization GO:0008104 205 0.032
regulation of multi organism process GO:0043900 69 0.032
aging GO:0007568 812 0.032
tissue morphogenesis GO:0048729 65 0.032
collagen and cuticulin based cuticle development GO:0040002 99 0.031
intracellular receptor signaling pathway GO:0030522 2 0.031
negative regulation of cell communication GO:0010648 61 0.031
male sex differentiation GO:0046661 86 0.030
innate immune response GO:0045087 190 0.030
determination of adult lifespan GO:0008340 812 0.029
regulation of cell cell adhesion GO:0022407 1 0.029
macromolecule modification GO:0043412 218 0.029
actomyosin structure organization GO:0031032 154 0.029
positive regulation of gene expression GO:0010628 112 0.028
cell death GO:0008219 547 0.028
single organism organelle organization GO:1902589 501 0.028
protein phosphorylation GO:0006468 85 0.027
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.027
establishment of localization in cell GO:0051649 318 0.027
axon development GO:0061564 163 0.027
striated muscle cell differentiation GO:0051146 158 0.027
negative regulation of response to stimulus GO:0048585 73 0.027
macromolecule biosynthetic process GO:0009059 250 0.027
locomotory behavior GO:0007626 40 0.027
negative regulation of rna biosynthetic process GO:1902679 53 0.027
regulation of signal transduction GO:0009966 135 0.027
Worm
response to other organism GO:0051707 101 0.027
cellular protein complex assembly GO:0043623 178 0.027
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.026
organic substance catabolic process GO:1901575 294 0.026
negative regulation of nucleic acid templated transcription GO:1903507 53 0.026
head development GO:0060322 1 0.026
organelle fission GO:0048285 363 0.025
homeostatic process GO:0042592 51 0.025
ion transport GO:0006811 113 0.025
negative regulation of locomotion GO:0040013 21 0.025
cellular protein metabolic process GO:0044267 279 0.025
cellular amine metabolic process GO:0044106 15 0.025
regulation of cell development GO:0060284 49 0.025
single organism transport GO:0044765 447 0.025
protein oligomerization GO:0051259 4 0.025
regulation of cellular ketone metabolic process GO:0010565 3 0.024
hermaphrodite genitalia development GO:0040035 734 0.024
cell proliferation GO:0008283 116 0.024
positive regulation of biosynthetic process GO:0009891 109 0.024
positive regulation of neurogenesis GO:0050769 4 0.024
regulation of intracellular signal transduction GO:1902531 77 0.024
cuticle development GO:0042335 100 0.024
cytoskeleton organization GO:0007010 339 0.024
neuromuscular junction development GO:0007528 2 0.024
cell fate commitment GO:0045165 139 0.023
Worm
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.023
oxidation reduction process GO:0055114 59 0.023
cell division GO:0051301 262 0.023
positive regulation of nucleic acid templated transcription GO:1903508 102 0.023
membrane invagination GO:0010324 98 0.023
negative regulation of biosynthetic process GO:0009890 65 0.023
regulation of cell death GO:0010941 65 0.022
signal transduction by phosphorylation GO:0023014 31 0.022
myofibril assembly GO:0030239 154 0.022
regulation of nervous system development GO:0051960 41 0.022
myosin filament organization GO:0031033 138 0.022
response to oxygen containing compound GO:1901700 44 0.022
striated muscle myosin thick filament assembly GO:0071688 138 0.021
negative regulation of molecular function GO:0044092 20 0.021
muscle organ morphogenesis GO:0048644 4 0.021
positive regulation of neuron differentiation GO:0045666 4 0.021
ribonucleoprotein complex assembly GO:0022618 4 0.021
hormone metabolic process GO:0042445 3 0.021
regulation of signaling GO:0023051 172 0.021
Worm
positive regulation of cell death GO:0010942 38 0.020
proteolysis GO:0006508 61 0.020
apoptotic process GO:0006915 478 0.020
positive regulation of programmed cell death GO:0043068 27 0.020
cell morphogenesis GO:0000902 163 0.020
cellular macromolecular complex assembly GO:0034622 184 0.020
neurological system process GO:0050877 53 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.019
response to wounding GO:0009611 4 0.019
regulation of cell cycle process GO:0010564 145 0.019
negative regulation of neurogenesis GO:0050768 4 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
mesoderm morphogenesis GO:0048332 24 0.019
phagocytosis GO:0006909 115 0.019
actin filament based process GO:0030029 191 0.019
cellular catabolic process GO:0044248 199 0.019
nematode male tail tip morphogenesis GO:0045138 77 0.018
negative regulation of neuron differentiation GO:0045665 4 0.018
male anatomical structure morphogenesis GO:0090598 78 0.018
actin cytoskeleton organization GO:0030036 184 0.018
tube morphogenesis GO:0035239 79 0.018
positive regulation of macromolecule metabolic process GO:0010604 149 0.018
regulation of epithelial cell proliferation GO:0050678 1 0.018
regulation of system process GO:0044057 27 0.017
regulation of apoptotic process GO:0042981 36 0.017
response to bacterium GO:0009617 86 0.017
regulation of cellular component size GO:0032535 40 0.017
monocarboxylic acid metabolic process GO:0032787 22 0.017
regeneration GO:0031099 4 0.017
regulation of organelle organization GO:0033043 164 0.017
neuron development GO:0048666 199 0.017
positive regulation of signal transduction GO:0009967 40 0.016
Worm
positive regulation of catalytic activity GO:0043085 59 0.016
epithelial tube morphogenesis GO:0060562 1 0.016
protein tetramerization GO:0051262 1 0.016
regulation of anatomical structure size GO:0090066 46 0.016
negative regulation of response to external stimulus GO:0032102 3 0.016
regulation of response to wounding GO:1903034 1 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 5 0.015
epithelial cell proliferation GO:0050673 1 0.015
cellular response to endogenous stimulus GO:0071495 32 0.015
regulation of vulval development GO:0040028 248 0.015
bmp signaling pathway GO:0030509 3 0.015
embryonic body morphogenesis GO:0010172 49 0.015
regulation of post embryonic development GO:0048580 260 0.015
cell morphogenesis involved in differentiation GO:0000904 112 0.015
organonitrogen compound metabolic process GO:1901564 151 0.015
engulfment of apoptotic cell GO:0043652 94 0.015
cell projection morphogenesis GO:0048858 148 0.015
protein complex subunit organization GO:0071822 280 0.014
regulation of cell division GO:0051302 142 0.014
cellular response to abiotic stimulus GO:0071214 4 0.014
regulation of protein modification process GO:0031399 46 0.014
canonical wnt signaling pathway GO:0060070 3 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
cellular response to nitrogen compound GO:1901699 24 0.014
excretion GO:0007588 49 0.014
g1 s transition of mitotic cell cycle GO:0000082 2 0.014
regulation of apoptotic signaling pathway GO:2001233 1 0.014
cell part morphogenesis GO:0032990 152 0.014
regulation of protein kinase activity GO:0045859 28 0.014
cell cycle g1 s phase transition GO:0044843 2 0.014
positive regulation of cellular metabolic process GO:0031325 178 0.014
regulation of reproductive process GO:2000241 66 0.014
positive regulation of rna metabolic process GO:0051254 103 0.014
phagocytosis engulfment GO:0006911 98 0.014
defense response to fungus GO:0050832 19 0.014
chromatin assembly or disassembly GO:0006333 1 0.014
muscle fiber development GO:0048747 2 0.014
regulation of phosphorus metabolic process GO:0051174 81 0.014
defense response to other organism GO:0098542 100 0.014
endodermal cell differentiation GO:0035987 18 0.014
response to inorganic substance GO:0010035 50 0.014
negative regulation of signal transduction GO:0009968 60 0.014
mapk cascade GO:0000165 31 0.014
cell recognition GO:0008037 85 0.013
myosin filament assembly GO:0031034 138 0.013
regulation of organ morphogenesis GO:2000027 4 0.013
regulation of transport GO:0051049 91 0.013
negative regulation of post embryonic development GO:0048581 208 0.013
amine metabolic process GO:0009308 15 0.013
modification of morphology or physiology of other organism GO:0035821 2 0.013
response to endogenous stimulus GO:0009719 33 0.013
regulation of phosphate metabolic process GO:0019220 81 0.013
fertilization GO:0009566 63 0.013
regulation of stem cell differentiation GO:2000736 1 0.013
regulation of gene expression epigenetic GO:0040029 163 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.013
apoptotic cell clearance GO:0043277 111 0.012
cellular ketone metabolic process GO:0042180 14 0.012
regulation of cellular component biogenesis GO:0044087 26 0.012
neuron projection morphogenesis GO:0048812 114 0.012
cellular response to stress GO:0033554 162 0.012
metal ion transport GO:0030001 49 0.012
dendrite development GO:0016358 42 0.012
positive regulation of neuron projection development GO:0010976 4 0.012
regulation of cell communication GO:0010646 176 0.012
Worm
adult behavior GO:0030534 3 0.012
positive regulation of epithelial cell proliferation GO:0050679 1 0.012
meiotic nuclear division GO:0007126 300 0.012
spermatogenesis GO:0007283 41 0.012
rna interference GO:0016246 137 0.012
defense response to gram negative bacterium GO:0050829 64 0.012
regulation of phosphorylation GO:0042325 45 0.012
regulation of protein localization GO:0032880 50 0.012
positive regulation of cell communication GO:0010647 69 0.011
Worm
programmed cell death GO:0012501 500 0.011
cellular response to oxygen containing compound GO:1901701 21 0.011
positive regulation of molecular function GO:0044093 61 0.011
regulation of protein stability GO:0031647 3 0.011
dna metabolic process GO:0006259 74 0.011
negative regulation of rna metabolic process GO:0051253 53 0.011
muscle organ development GO:0007517 26 0.011
cell projection organization GO:0030030 231 0.011
ribose phosphate metabolic process GO:0019693 99 0.011
carbohydrate derivative metabolic process GO:1901135 141 0.011
male gamete generation GO:0048232 41 0.011
sensory organ morphogenesis GO:0090596 2 0.011
regulation of meiotic cell cycle GO:0051445 136 0.011
mrna metabolic process GO:0016071 31 0.010
phosphate containing compound metabolic process GO:0006796 232 0.010
detection of external stimulus GO:0009581 4 0.010
regulation of nucleocytoplasmic transport GO:0046822 3 0.010
rrna metabolic process GO:0016072 3 0.010
posttranscriptional gene silencing by rna GO:0035194 143 0.010
positive regulation of protein transport GO:0051222 4 0.010
pigment metabolic process GO:0042440 2 0.010

brp-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.010